

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 9.44599695 |
| 2 | negative regulation of glucose transport (GO:0010829) | 8.90760918 |
| 3 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 8.69401121 |
| 4 | interleukin-6-mediated signaling pathway (GO:0070102) | 6.91129315 |
| 5 | ER overload response (GO:0006983) | 6.42634420 |
| 6 | signal peptide processing (GO:0006465) | 6.19652068 |
| 7 | cellular response to ethanol (GO:0071361) | 5.80917643 |
| 8 | GDP-mannose metabolic process (GO:0019673) | 5.32437716 |
| 9 | protein maturation by protein folding (GO:0022417) | 4.86516923 |
| 10 | histone-serine phosphorylation (GO:0035404) | 4.78449366 |
| 11 | histone H3-K4 trimethylation (GO:0080182) | 4.72252678 |
| 12 | negative regulation of cellular response to insulin stimulus (GO:1900077) | 4.58405346 |
| 13 | regulation of energy homeostasis (GO:2000505) | 4.56775865 |
| 14 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 4.37984258 |
| 15 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 4.37984258 |
| 16 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 4.36745791 |
| 17 | lipopolysaccharide biosynthetic process (GO:0009103) | 4.20401369 |
| 18 | cellular response to glucose starvation (GO:0042149) | 4.18709291 |
| 19 | ER-associated ubiquitin-dependent protein catabolic process (GO:0030433) | 4.12467322 |
| 20 | rRNA catabolic process (GO:0016075) | 3.97805249 |
| 21 | mannose metabolic process (GO:0006013) | 3.97150813 |
| 22 | negative regulation of glycogen biosynthetic process (GO:0045719) | 3.95071263 |
| 23 | lipopolysaccharide metabolic process (GO:0008653) | 3.94749233 |
| 24 | hepatocyte apoptotic process (GO:0097284) | 3.92443150 |
| 25 | proline transport (GO:0015824) | 3.83711855 |
| 26 | cellular response to exogenous dsRNA (GO:0071360) | 3.82875035 |
| 27 | nucleotide-sugar biosynthetic process (GO:0009226) | 3.82718808 |
| 28 | regulation of fibroblast apoptotic process (GO:2000269) | 3.79681412 |
| 29 | definitive hemopoiesis (GO:0060216) | 3.74520998 |
| 30 | peptidyl-lysine trimethylation (GO:0018023) | 3.74388633 |
| 31 | positive regulation of protein homooligomerization (GO:0032464) | 3.71275914 |
| 32 | embryonic process involved in female pregnancy (GO:0060136) | 3.70125103 |
| 33 | natural killer cell activation involved in immune response (GO:0002323) | 3.68066012 |
| 34 | regulation of MHC class I biosynthetic process (GO:0045343) | 3.66132702 |
| 35 | regulation of B cell proliferation (GO:0030888) | 3.63225096 |
| 36 | positive regulation of phosphatase activity (GO:0010922) | 3.63057871 |
| 37 | indolalkylamine metabolic process (GO:0006586) | 3.58857502 |
| 38 | regulation of DNA endoreduplication (GO:0032875) | 3.57681249 |
| 39 | labyrinthine layer development (GO:0060711) | 3.53610420 |
| 40 | NIK/NF-kappaB signaling (GO:0038061) | 3.48054543 |
| 41 | positive regulation of histone H3-K4 methylation (GO:0051571) | 3.47842697 |
| 42 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.42039829 |
| 43 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.42039829 |
| 44 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.42039829 |
| 45 | cobalamin metabolic process (GO:0009235) | 3.41267639 |
| 46 | response to hydroperoxide (GO:0033194) | 3.30740490 |
| 47 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.22227910 |
| 48 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 3.20796425 |
| 49 | positive regulation of glycolytic process (GO:0045821) | 3.13925873 |
| 50 | cytokine biosynthetic process (GO:0042089) | 3.13236732 |
| 51 | folic acid metabolic process (GO:0046655) | 3.11902431 |
| 52 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.10323498 |
| 53 | positive regulation of steroid biosynthetic process (GO:0010893) | 3.08810388 |
| 54 | rRNA methylation (GO:0031167) | 3.07201069 |
| 55 | nucleotide-sugar metabolic process (GO:0009225) | 3.07095826 |
| 56 | fatty acid homeostasis (GO:0055089) | 3.06491993 |
| 57 | pseudouridine synthesis (GO:0001522) | 3.05105488 |
| 58 | cellular response to interleukin-6 (GO:0071354) | 3.02053693 |
| 59 | I-kappaB kinase/NF-kappaB signaling (GO:0007249) | 3.02004138 |
| 60 | methionine biosynthetic process (GO:0009086) | 2.96714256 |
| 61 | negative regulation of glycogen metabolic process (GO:0070874) | 2.96463705 |
| 62 | nucleoside diphosphate catabolic process (GO:0009134) | 2.95448812 |
| 63 | snRNA transcription (GO:0009301) | 2.88853658 |
| 64 | glycosylceramide metabolic process (GO:0006677) | 2.88438829 |
| 65 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 2.87673533 |
| 66 | tyrosine phosphorylation of STAT protein (GO:0007260) | 2.87361663 |
| 67 | transcytosis (GO:0045056) | 2.87229832 |
| 68 | N-terminal protein amino acid acetylation (GO:0006474) | 2.86360037 |
| 69 | natural killer cell differentiation (GO:0001779) | 2.86226250 |
| 70 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 2.85491774 |
| 71 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.85454363 |
| 72 | positive regulation of steroid hormone secretion (GO:2000833) | 2.83777235 |
| 73 | regulation of triglyceride catabolic process (GO:0010896) | 2.80221603 |
| 74 | transcription from mitochondrial promoter (GO:0006390) | 2.78545249 |
| 75 | histone deubiquitination (GO:0016578) | 2.78470867 |
| 76 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.77026077 |
| 77 | developmental pigmentation (GO:0048066) | 2.73584049 |
| 78 | positive regulation of alcohol biosynthetic process (GO:1902932) | 2.72975730 |
| 79 | intrinsic apoptotic signaling pathway in response to oxidative stress (GO:0008631) | 2.71958252 |
| 80 | negative regulation of lipid catabolic process (GO:0050995) | 2.71827976 |
| 81 | glycolipid catabolic process (GO:0019377) | 2.71254734 |
| 82 | regulation of Rac protein signal transduction (GO:0035020) | 2.70076166 |
| 83 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.66636582 |
| 84 | peptidyl-lysine methylation (GO:0018022) | 2.65970252 |
| 85 | negative regulation by host of viral transcription (GO:0043922) | 2.65496376 |
| 86 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.64178810 |
| 87 | cellular response to unfolded protein (GO:0034620) | 2.64132631 |
| 88 | response to caffeine (GO:0031000) | 2.63263365 |
| 89 | positive regulation of autophagy (GO:0010508) | 2.63056050 |
| 90 | regulation of cellular extravasation (GO:0002691) | 2.62997112 |
| 91 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.61800483 |
| 92 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.61606791 |
| 93 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.61606791 |
| 94 | cytokine metabolic process (GO:0042107) | 2.60309440 |
| 95 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.59941523 |
| 96 | inositol metabolic process (GO:0006020) | 2.58828965 |
| 97 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 2.58112098 |
| 98 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.57196696 |
| 99 | cellular response to dsRNA (GO:0071359) | 2.56968937 |
| 100 | negative regulation of glucose import (GO:0046325) | 10.1013500 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.53939627 |
| 2 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 3.48290257 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.22448270 |
| 4 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.98482886 |
| 5 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.59149056 |
| 6 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.46022033 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.25993718 |
| 8 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.23624801 |
| 9 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.06298792 |
| 10 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.03602780 |
| 11 | ER_23166858_ChIP-Seq_MCF-7_Human | 2.02565327 |
| 12 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.91517954 |
| 13 | GATA3_26560356_Chip-Seq_TH2_Human | 1.87862717 |
| 14 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.83458047 |
| 15 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.81644662 |
| 16 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.78171867 |
| 17 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.67913069 |
| 18 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.64469545 |
| 19 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.63471885 |
| 20 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.58456052 |
| 21 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.57948305 |
| 22 | MYB_26560356_Chip-Seq_TH2_Human | 1.55711712 |
| 23 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.55188319 |
| 24 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.53081226 |
| 25 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.51386167 |
| 26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.51167676 |
| 27 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.50892599 |
| 28 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.50449889 |
| 29 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.45419544 |
| 30 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.45196228 |
| 31 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.44848564 |
| 32 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.44276836 |
| 33 | EWS_26573619_Chip-Seq_HEK293_Human | 1.43945702 |
| 34 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.43366408 |
| 35 | GATA1_22025678_ChIP-Seq_K562_Human | 1.43088486 |
| 36 | P300_19829295_ChIP-Seq_ESCs_Human | 1.42541666 |
| 37 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.41153215 |
| 38 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.39860962 |
| 39 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.39803618 |
| 40 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.39187911 |
| 41 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.38687015 |
| 42 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.37585589 |
| 43 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.35978561 |
| 44 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.35475118 |
| 45 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.35075971 |
| 46 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.35075971 |
| 47 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.31669918 |
| 48 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.31387760 |
| 49 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.28858875 |
| 50 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.28230748 |
| 51 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.28115455 |
| 52 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.28058263 |
| 53 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.26212158 |
| 54 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.26020556 |
| 55 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.25787324 |
| 56 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.24295085 |
| 57 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.23547126 |
| 58 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.22038006 |
| 59 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21027500 |
| 60 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.20465213 |
| 61 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.20264393 |
| 62 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.19856259 |
| 63 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.17412845 |
| 64 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.14720523 |
| 65 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.14432467 |
| 66 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.14369392 |
| 67 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.14369392 |
| 68 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.14144949 |
| 69 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.13662830 |
| 70 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.12102863 |
| 71 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.11681434 |
| 72 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.11363993 |
| 73 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.10658285 |
| 74 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.10558127 |
| 75 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.09790349 |
| 76 | AR_25329375_ChIP-Seq_VCAP_Human | 1.08725719 |
| 77 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.07406281 |
| 78 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 1.06114918 |
| 79 | TCF4_23295773_ChIP-Seq_U87_Human | 1.05737493 |
| 80 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.05579161 |
| 81 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.05544241 |
| 82 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.05044397 |
| 83 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.03497709 |
| 84 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.03386496 |
| 85 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.03268430 |
| 86 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.03174794 |
| 87 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.02944222 |
| 88 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.02767560 |
| 89 | GATA3_26560356_Chip-Seq_TH1_Human | 0.99768542 |
| 90 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.99475099 |
| 91 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.97788827 |
| 92 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.97636398 |
| 93 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.97553117 |
| 94 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.97310293 |
| 95 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.96326681 |
| 96 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.95914121 |
| 97 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.95569788 |
| 98 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.94650981 |
| 99 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.92840766 |
| 100 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.92164329 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000015_abnormal_ear_pigmentation | 5.26037207 |
| 2 | MP0000569_abnormal_digit_pigmentation | 3.70171958 |
| 3 | MP0003950_abnormal_plasma_membrane | 3.19405510 |
| 4 | MP0010386_abnormal_urinary_bladder | 2.98509854 |
| 5 | MP0003656_abnormal_erythrocyte_physiolo | 2.97696561 |
| 6 | MP0003195_calcinosis | 2.95399318 |
| 7 | MP0002254_reproductive_system_inflammat | 2.77558389 |
| 8 | MP0004036_abnormal_muscle_relaxation | 2.67583068 |
| 9 | MP0002653_abnormal_ependyma_morphology | 2.61002251 |
| 10 | MP0005671_abnormal_response_to | 2.55272647 |
| 11 | MP0001529_abnormal_vocalization | 2.54441914 |
| 12 | MP0004084_abnormal_cardiac_muscle | 2.37398006 |
| 13 | MP0003718_maternal_effect | 2.35319443 |
| 14 | MP0002148_abnormal_hypersensitivity_rea | 2.29725845 |
| 15 | MP0004145_abnormal_muscle_electrophysio | 2.19323556 |
| 16 | MP0008877_abnormal_DNA_methylation | 2.18507780 |
| 17 | MP0003045_fibrosis | 2.15580122 |
| 18 | MP0001800_abnormal_humoral_immune | 2.09445223 |
| 19 | MP0002095_abnormal_skin_pigmentation | 2.02689985 |
| 20 | MP0001666_abnormal_nutrient_absorption | 1.78434424 |
| 21 | MP0005174_abnormal_tail_pigmentation | 1.77175452 |
| 22 | MP0005332_abnormal_amino_acid | 1.76048437 |
| 23 | MP0001835_abnormal_antigen_presentation | 1.74777856 |
| 24 | MP0004808_abnormal_hematopoietic_stem | 1.69155856 |
| 25 | MP0005464_abnormal_platelet_physiology | 1.67981868 |
| 26 | MP0004130_abnormal_muscle_cell | 1.65592994 |
| 27 | MP0003868_abnormal_feces_composition | 1.62985520 |
| 28 | MP0002277_abnormal_respiratory_mucosa | 1.62245929 |
| 29 | MP0005395_other_phenotype | 1.56567821 |
| 30 | MP0002452_abnormal_antigen_presenting | 1.55714857 |
| 31 | MP0001501_abnormal_sleep_pattern | 1.51125746 |
| 32 | MP0008872_abnormal_physiological_respon | 1.49585440 |
| 33 | MP0005000_abnormal_immune_tolerance | 1.46983852 |
| 34 | MP0005397_hematopoietic_system_phenotyp | 1.37028052 |
| 35 | MP0001545_abnormal_hematopoietic_system | 1.37028052 |
| 36 | MP0002723_abnormal_immune_serum | 1.36443024 |
| 37 | MP0002168_other_aberrant_phenotype | 1.29533171 |
| 38 | MP0002102_abnormal_ear_morphology | 1.23287769 |
| 39 | MP0008007_abnormal_cellular_replicative | 1.22969130 |
| 40 | MP0002693_abnormal_pancreas_physiology | 1.22498025 |
| 41 | MP0001873_stomach_inflammation | 1.21892038 |
| 42 | MP0005551_abnormal_eye_electrophysiolog | 1.20895745 |
| 43 | MP0005171_absent_coat_pigmentation | 1.20378022 |
| 44 | MP0002420_abnormal_adaptive_immunity | 1.20347540 |
| 45 | MP0004142_abnormal_muscle_tone | 1.18932026 |
| 46 | MP0001819_abnormal_immune_cell | 1.18708137 |
| 47 | MP0002398_abnormal_bone_marrow | 1.15357380 |
| 48 | MP0000689_abnormal_spleen_morphology | 1.14369007 |
| 49 | MP0009764_decreased_sensitivity_to | 1.12596102 |
| 50 | MP0005167_abnormal_blood-brain_barrier | 1.12122569 |
| 51 | MP0000371_diluted_coat_color | 1.09213658 |
| 52 | MP0005386_behavior/neurological_phenoty | 1.08149929 |
| 53 | MP0004924_abnormal_behavior | 1.08149929 |
| 54 | MP0001919_abnormal_reproductive_system | 1.07119708 |
| 55 | MP0002138_abnormal_hepatobiliary_system | 1.06382129 |
| 56 | MP0002396_abnormal_hematopoietic_system | 1.06103231 |
| 57 | MP0008875_abnormal_xenobiotic_pharmacok | 1.03388050 |
| 58 | MP0005365_abnormal_bile_salt | 1.00391957 |
| 59 | MP0002132_abnormal_respiratory_system | 0.99635531 |
| 60 | MP0001191_abnormal_skin_condition | 0.98591249 |
| 61 | MP0000716_abnormal_immune_system | 0.96994836 |
| 62 | MP0000685_abnormal_immune_system | 0.94919433 |
| 63 | MP0002136_abnormal_kidney_physiology | 0.93427381 |
| 64 | MP0004742_abnormal_vestibular_system | 0.92979281 |
| 65 | MP0002876_abnormal_thyroid_physiology | 0.92920676 |
| 66 | MP0002419_abnormal_innate_immunity | 0.92870612 |
| 67 | MP0003252_abnormal_bile_duct | 0.92381932 |
| 68 | MP0001845_abnormal_inflammatory_respons | 0.90673353 |
| 69 | MP0004270_analgesia | 0.90043042 |
| 70 | MP0005085_abnormal_gallbladder_physiolo | 0.89831667 |
| 71 | MP0002933_joint_inflammation | 0.89688128 |
| 72 | MP0000372_irregular_coat_pigmentation | 0.88941131 |
| 73 | MP0002295_abnormal_pulmonary_circulatio | 0.87022708 |
| 74 | MP0001986_abnormal_taste_sensitivity | 0.86061633 |
| 75 | MP0005075_abnormal_melanosome_morpholog | 0.86010616 |
| 76 | MP0001727_abnormal_embryo_implantation | 0.85684599 |
| 77 | MP0001764_abnormal_homeostasis | 0.84305465 |
| 78 | MP0000427_abnormal_hair_cycle | 0.84086292 |
| 79 | MP0002127_abnormal_cardiovascular_syste | 0.84034164 |
| 80 | MP0002722_abnormal_immune_system | 0.83744679 |
| 81 | MP0004885_abnormal_endolymph | 0.80641334 |
| 82 | MP0000639_abnormal_adrenal_gland | 0.79286812 |
| 83 | MP0002429_abnormal_blood_cell | 0.78748930 |
| 84 | MP0005448_abnormal_energy_balance | 0.76109289 |
| 85 | MP0009697_abnormal_copulation | 0.75862088 |
| 86 | MP0001765_abnormal_ion_homeostasis | 0.72960964 |
| 87 | MP0003646_muscle_fatigue | 0.70732011 |
| 88 | MP0005645_abnormal_hypothalamus_physiol | 0.70445739 |
| 89 | MP0004043_abnormal_pH_regulation | 0.69014864 |
| 90 | MP0003763_abnormal_thymus_physiology | 0.66529478 |
| 91 | MP0003943_abnormal_hepatobiliary_system | 0.66243460 |
| 92 | MP0004134_abnormal_chest_morphology | 0.64397136 |
| 93 | MP0001348_abnormal_lacrimal_gland | 0.63434661 |
| 94 | MP0009745_abnormal_behavioral_response | 0.62338486 |
| 95 | MP0004484_altered_response_of | 0.61991475 |
| 96 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.61286940 |
| 97 | MP0005389_reproductive_system_phenotype | 0.60175348 |
| 98 | MP0003303_peritoneal_inflammation | 0.59156205 |
| 99 | MP0000538_abnormal_urinary_bladder | 0.58908737 |
| 100 | MP0000470_abnormal_stomach_morphology | 0.58215302 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nonimmune hydrops fetalis (HP:0001790) | 7.46538479 |
| 2 | Type I transferrin isoform profile (HP:0003642) | 5.88893260 |
| 3 | Reduced antithrombin III activity (HP:0001976) | 5.55662774 |
| 4 | Hypoplasia of the pons (HP:0012110) | 5.31511303 |
| 5 | Abnormality of the pons (HP:0007361) | 5.01126232 |
| 6 | Spastic paraparesis (HP:0002313) | 4.43500501 |
| 7 | Abnormal protein glycosylation (HP:0012346) | 4.27969289 |
| 8 | Abnormal glycosylation (HP:0012345) | 4.27969289 |
| 9 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 4.27969289 |
| 10 | Abnormal protein N-linked glycosylation (HP:0012347) | 4.27969289 |
| 11 | Thrombocytosis (HP:0001894) | 4.23726018 |
| 12 | Megaloblastic anemia (HP:0001889) | 4.16170918 |
| 13 | Testicular atrophy (HP:0000029) | 4.08579687 |
| 14 | Global brain atrophy (HP:0002283) | 3.96934457 |
| 15 | Abnormality of the intrinsic pathway (HP:0010989) | 3.71089404 |
| 16 | Cutaneous melanoma (HP:0012056) | 3.68300333 |
| 17 | Glucose intolerance (HP:0000833) | 3.65970875 |
| 18 | Acute hepatic failure (HP:0006554) | 3.64999260 |
| 19 | Prolonged partial thromboplastin time (HP:0003645) | 3.58279227 |
| 20 | Abnormality of homocysteine metabolism (HP:0010919) | 3.42533505 |
| 21 | Homocystinuria (HP:0002156) | 3.42533505 |
| 22 | Nuclear cataract (HP:0100018) | 3.34570047 |
| 23 | Chronic sinusitis (HP:0011109) | 3.18571988 |
| 24 | Hypokinesia (HP:0002375) | 3.09786021 |
| 25 | Follicular hyperkeratosis (HP:0007502) | 3.07582233 |
| 26 | Albinism (HP:0001022) | 3.05970406 |
| 27 | Abnormal albumin level (HP:0012116) | 3.02607905 |
| 28 | Hypoalbuminemia (HP:0003073) | 3.02607905 |
| 29 | Vacuolated lymphocytes (HP:0001922) | 2.91214155 |
| 30 | Agammaglobulinemia (HP:0004432) | 2.90602500 |
| 31 | Curly hair (HP:0002212) | 2.83240147 |
| 32 | Gingival bleeding (HP:0000225) | 2.82565284 |
| 33 | IgA deficiency (HP:0002720) | 2.82517774 |
| 34 | Paraparesis (HP:0002385) | 2.81269658 |
| 35 | Hyperglycinuria (HP:0003108) | 2.80310507 |
| 36 | Hydroxyprolinuria (HP:0003080) | 2.75864038 |
| 37 | Abnormality of proline metabolism (HP:0010907) | 2.75864038 |
| 38 | Stomatitis (HP:0010280) | 2.63966248 |
| 39 | Poor eye contact (HP:0000817) | 2.59764667 |
| 40 | Abnormal glucose tolerance (HP:0001952) | 2.57503381 |
| 41 | Spontaneous abortion (HP:0005268) | 2.54202332 |
| 42 | Pancreatic cysts (HP:0001737) | 2.51624656 |
| 43 | Proximal tubulopathy (HP:0000114) | 2.44402002 |
| 44 | Keratoconus (HP:0000563) | 2.43831211 |
| 45 | Increased corneal curvature (HP:0100692) | 2.43831211 |
| 46 | Abnormality of methionine metabolism (HP:0010901) | 2.38253225 |
| 47 | Hypothermia (HP:0002045) | 2.37324817 |
| 48 | IgG deficiency (HP:0004315) | 2.37181601 |
| 49 | Gastrointestinal infarctions (HP:0005244) | 2.33732425 |
| 50 | Entropion (HP:0000621) | 2.31034845 |
| 51 | Verrucae (HP:0200043) | 2.30686738 |
| 52 | Papilloma (HP:0012740) | 2.30686738 |
| 53 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.29389795 |
| 54 | Recurrent pneumonia (HP:0006532) | 2.28696383 |
| 55 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.27259100 |
| 56 | Progressive sensorineural hearing impairment (HP:0000408) | 2.22330153 |
| 57 | Exocrine pancreatic insufficiency (HP:0001738) | 2.19074225 |
| 58 | Keratitis (HP:0000491) | 2.17408275 |
| 59 | Severe visual impairment (HP:0001141) | 2.17259666 |
| 60 | Chronic hepatic failure (HP:0100626) | 2.14873669 |
| 61 | Vertebral compression fractures (HP:0002953) | 2.13710482 |
| 62 | Abnormality of vitamin B metabolism (HP:0004340) | 2.12591699 |
| 63 | Neutropenia (HP:0001875) | 2.08355196 |
| 64 | Abnormality of the prostate (HP:0008775) | 2.05694415 |
| 65 | Abnormal social behavior (HP:0012433) | 2.03459819 |
| 66 | Impaired social interactions (HP:0000735) | 2.03459819 |
| 67 | Portal hypertension (HP:0001409) | 2.01345283 |
| 68 | Congenital stationary night blindness (HP:0007642) | 1.99666405 |
| 69 | Cerebral hemorrhage (HP:0001342) | 1.99326189 |
| 70 | Peritonitis (HP:0002586) | 1.98711004 |
| 71 | Poikiloderma (HP:0001029) | 1.96608990 |
| 72 | Abnormality of the pericardium (HP:0001697) | 1.96292766 |
| 73 | Deep philtrum (HP:0002002) | 1.94877450 |
| 74 | Vascular calcification (HP:0004934) | 1.92608957 |
| 75 | Microvesicular hepatic steatosis (HP:0001414) | 1.91783003 |
| 76 | Pancreatic fibrosis (HP:0100732) | 1.91767981 |
| 77 | Metaphyseal dysplasia (HP:0100255) | 1.91628904 |
| 78 | Stroke (HP:0001297) | 1.90914802 |
| 79 | Myocardial infarction (HP:0001658) | 1.89465382 |
| 80 | Chest pain (HP:0100749) | 1.88387954 |
| 81 | Abnormality of the hepatic vasculature (HP:0006707) | 1.87969011 |
| 82 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.85346248 |
| 83 | Abnormality of glycine metabolism (HP:0010895) | 1.83315725 |
| 84 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.83315725 |
| 85 | Generalized hypopigmentation of hair (HP:0011358) | 1.82847368 |
| 86 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.82078323 |
| 87 | True hermaphroditism (HP:0010459) | 1.78683667 |
| 88 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.77682376 |
| 89 | Pulmonary infiltrates (HP:0002113) | 1.77552278 |
| 90 | Epistaxis (HP:0000421) | 1.76333648 |
| 91 | Asymmetry of the thorax (HP:0001555) | 1.76013974 |
| 92 | Esotropia (HP:0000565) | 1.75018171 |
| 93 | Diminished movement (HP:0002374) | 1.73746142 |
| 94 | Exertional dyspnea (HP:0002875) | 1.71224514 |
| 95 | Hypoproteinemia (HP:0003075) | 1.70884630 |
| 96 | Decreased circulating renin level (HP:0003351) | 1.70398033 |
| 97 | Abnormality of subcutaneous fat tissue (HP:0001001) | 1.69326867 |
| 98 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.68900514 |
| 99 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.68900514 |
| 100 | Abnormality of glycolipid metabolism (HP:0010969) | 1.68900514 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CAMKK2 | 7.09858939 |
| 2 | BRSK2 | 6.60149706 |
| 3 | PKN2 | 5.27814340 |
| 4 | FLT3 | 4.24110789 |
| 5 | AKT3 | 3.54565806 |
| 6 | CAMKK1 | 3.34718354 |
| 7 | BRSK1 | 2.64728145 |
| 8 | IRAK2 | 2.58887043 |
| 9 | IRAK1 | 2.35555977 |
| 10 | IRAK4 | 2.32762841 |
| 11 | EIF2AK3 | 2.31166680 |
| 12 | PIK3CG | 2.28785077 |
| 13 | TEC | 1.99526624 |
| 14 | BMPR1B | 1.88817520 |
| 15 | FRK | 1.60181045 |
| 16 | TLK1 | 1.34593230 |
| 17 | MET | 1.32756594 |
| 18 | MAPKAPK5 | 1.29754811 |
| 19 | ITK | 1.26932598 |
| 20 | ACVR1B | 1.26651851 |
| 21 | PASK | 1.20733280 |
| 22 | LATS1 | 1.18742348 |
| 23 | BTK | 1.15799869 |
| 24 | NUAK1 | 1.12966227 |
| 25 | TAOK3 | 1.09062185 |
| 26 | TYK2 | 1.04259119 |
| 27 | WNK4 | 1.02702286 |
| 28 | MAP3K9 | 1.02459592 |
| 29 | PAK3 | 1.00522718 |
| 30 | MKNK2 | 0.99647831 |
| 31 | TXK | 0.99401520 |
| 32 | MST4 | 0.95003310 |
| 33 | SIK3 | 0.92217754 |
| 34 | STK38L | 0.88275023 |
| 35 | IKBKE | 0.87908268 |
| 36 | SYK | 0.86027064 |
| 37 | PDK2 | 0.85355268 |
| 38 | JAK3 | 0.83064206 |
| 39 | HCK | 0.80565568 |
| 40 | MAP3K14 | 0.78737673 |
| 41 | PRKAA2 | 0.76990578 |
| 42 | STK24 | 0.76961930 |
| 43 | MAPKAPK3 | 0.76150098 |
| 44 | CAMK1D | 0.74777592 |
| 45 | MAPK11 | 0.71803584 |
| 46 | MKNK1 | 0.68946666 |
| 47 | INSRR | 0.68514600 |
| 48 | PKN1 | 0.67657202 |
| 49 | TBK1 | 0.63478427 |
| 50 | CAMK1 | 0.63440792 |
| 51 | STK3 | 0.61574485 |
| 52 | IGF1R | 0.61080658 |
| 53 | TIE1 | 0.59193522 |
| 54 | MAP3K12 | 0.58237043 |
| 55 | ERBB3 | 0.57431246 |
| 56 | STK11 | 0.57128123 |
| 57 | GRK1 | 0.55218087 |
| 58 | IKBKB | 0.54057296 |
| 59 | STK4 | 0.41685574 |
| 60 | BLK | 0.41470575 |
| 61 | TRPM7 | 0.37964153 |
| 62 | JAK2 | 0.37805927 |
| 63 | CHUK | 0.37237104 |
| 64 | OXSR1 | 0.37098302 |
| 65 | BUB1 | 0.37088641 |
| 66 | PRKCQ | 0.36659377 |
| 67 | CAMK1G | 0.35394035 |
| 68 | MAPK13 | 0.34350523 |
| 69 | FGFR1 | 0.34312985 |
| 70 | BRD4 | 0.31241107 |
| 71 | MAP3K5 | 0.31240157 |
| 72 | PRKAA1 | 0.31066364 |
| 73 | ABL1 | 0.30778385 |
| 74 | EIF2AK2 | 0.30511294 |
| 75 | BCKDK | 0.28727316 |
| 76 | PNCK | 0.27837493 |
| 77 | KIT | 0.26796403 |
| 78 | MELK | 0.23488901 |
| 79 | CHEK1 | 0.21126799 |
| 80 | RPS6KB2 | 0.19197690 |
| 81 | ADRBK2 | 0.19155998 |
| 82 | WNK1 | 0.15885921 |
| 83 | CAMK4 | 0.15394062 |
| 84 | ADRBK1 | 0.15385544 |
| 85 | MAPK3 | 0.14137375 |
| 86 | SGK2 | 0.13533506 |
| 87 | BMPR2 | 0.13255670 |
| 88 | MAP3K6 | 0.13125506 |
| 89 | GRK7 | 0.12541890 |
| 90 | CAMK2B | 0.12394932 |
| 91 | VRK2 | 0.11404542 |
| 92 | PDK1 | 0.11279945 |
| 93 | TRIM28 | 0.11255847 |
| 94 | STK39 | 0.11250513 |
| 95 | LYN | 0.10503526 |
| 96 | TGFBR1 | 0.10416250 |
| 97 | RET | 0.10071979 |
| 98 | GRK5 | 0.08561198 |
| 99 | MAPK1 | 0.08451474 |
| 100 | VRK1 | 0.08441827 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Protein export_Homo sapiens_hsa03060 | 5.85884819 |
| 2 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.90186859 |
| 3 | Asthma_Homo sapiens_hsa05310 | 3.27112986 |
| 4 | Basal transcription factors_Homo sapiens_hsa03022 | 2.80404819 |
| 5 | Regulation of autophagy_Homo sapiens_hsa04140 | 2.75390868 |
| 6 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 2.46662154 |
| 7 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.33916801 |
| 8 | Pancreatic secretion_Homo sapiens_hsa04972 | 2.30072506 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.07807204 |
| 10 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.06895138 |
| 11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.96356066 |
| 12 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.95239767 |
| 13 | Circadian rhythm_Homo sapiens_hsa04710 | 1.88235628 |
| 14 | RNA degradation_Homo sapiens_hsa03018 | 1.76391188 |
| 15 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.74298141 |
| 16 | Olfactory transduction_Homo sapiens_hsa04740 | 1.73766104 |
| 17 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.71858538 |
| 18 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.70097686 |
| 19 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.64343881 |
| 20 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.64026288 |
| 21 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.47860889 |
| 22 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.46378398 |
| 23 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.29494712 |
| 24 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.28261354 |
| 25 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.22012589 |
| 26 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.20669057 |
| 27 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.18589740 |
| 28 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.15775191 |
| 29 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.11426348 |
| 30 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.09261767 |
| 31 | RNA polymerase_Homo sapiens_hsa03020 | 1.07969901 |
| 32 | Phototransduction_Homo sapiens_hsa04744 | 1.05923704 |
| 33 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.02965245 |
| 34 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.98964517 |
| 35 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.95976134 |
| 36 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.91679176 |
| 37 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.91553016 |
| 38 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.91474861 |
| 39 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.90664444 |
| 40 | Proteasome_Homo sapiens_hsa03050 | 0.90087623 |
| 41 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.89840034 |
| 42 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.85856490 |
| 43 | Viral myocarditis_Homo sapiens_hsa05416 | 0.85024283 |
| 44 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.84375269 |
| 45 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.84335992 |
| 46 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.83635916 |
| 47 | Leishmaniasis_Homo sapiens_hsa05140 | 0.82976493 |
| 48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.82452963 |
| 49 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.80962207 |
| 50 | Other glycan degradation_Homo sapiens_hsa00511 | 0.80317903 |
| 51 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.79323962 |
| 52 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.72559241 |
| 53 | Influenza A_Homo sapiens_hsa05164 | 0.70379332 |
| 54 | Homologous recombination_Homo sapiens_hsa03440 | 0.69171149 |
| 55 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.68294420 |
| 56 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.67424037 |
| 57 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.64717015 |
| 58 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.63669142 |
| 59 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.62338703 |
| 60 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.61768441 |
| 61 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.61377837 |
| 62 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.61304899 |
| 63 | Legionellosis_Homo sapiens_hsa05134 | 0.61199189 |
| 64 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.60675242 |
| 65 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.59823238 |
| 66 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.59096582 |
| 67 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.57148479 |
| 68 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.53129502 |
| 69 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.52871969 |
| 70 | Tuberculosis_Homo sapiens_hsa05152 | 0.50246753 |
| 71 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.50017027 |
| 72 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.45579599 |
| 73 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.44620518 |
| 74 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.44310340 |
| 75 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.43819014 |
| 76 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.43715624 |
| 77 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.43591346 |
| 78 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.41875594 |
| 79 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.40538444 |
| 80 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.40405048 |
| 81 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.39710122 |
| 82 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.39071465 |
| 83 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.38361807 |
| 84 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.36849659 |
| 85 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.36539567 |
| 86 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.36144473 |
| 87 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.34752064 |
| 88 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.34602909 |
| 89 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.34271017 |
| 90 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.33978061 |
| 91 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.31184363 |
| 92 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.30474970 |
| 93 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.29450546 |
| 94 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.28628856 |
| 95 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.27659024 |
| 96 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.27092646 |
| 97 | Taste transduction_Homo sapiens_hsa04742 | 0.26837410 |
| 98 | Salivary secretion_Homo sapiens_hsa04970 | 0.26348927 |
| 99 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.25563684 |
| 100 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.23807823 |

