

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | detection of molecule of bacterial origin (GO:0032490) | 5.86944917 |
| 2 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.81626781 |
| 3 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 5.78417485 |
| 4 | microglial cell activation (GO:0001774) | 5.63322301 |
| 5 | cellular response to ethanol (GO:0071361) | 5.45096706 |
| 6 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.25145600 |
| 7 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.25145600 |
| 8 | modulation by symbiont of host immune response (GO:0052553) | 5.25145600 |
| 9 | positive regulation by symbiont of host defense response (GO:0052509) | 5.25145600 |
| 10 | modulation by symbiont of host defense response (GO:0052031) | 5.25145600 |
| 11 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.25145600 |
| 12 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.85658936 |
| 13 | macrophage activation involved in immune response (GO:0002281) | 4.81018463 |
| 14 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.46581564 |
| 15 | macrophage activation (GO:0042116) | 4.45302735 |
| 16 | regulation of gamma-delta T cell activation (GO:0046643) | 4.44313900 |
| 17 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.37374793 |
| 18 | response to host immune response (GO:0052572) | 4.37374793 |
| 19 | histone H3-K36 demethylation (GO:0070544) | 4.23039377 |
| 20 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.13638368 |
| 21 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.12705203 |
| 22 | negative regulation of interleukin-12 production (GO:0032695) | 4.08978682 |
| 23 | detection of external biotic stimulus (GO:0098581) | 4.05728219 |
| 24 | response to host (GO:0075136) | 4.03345012 |
| 25 | response to host defenses (GO:0052200) | 4.03345012 |
| 26 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 4.03345012 |
| 27 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.95484806 |
| 28 | negative regulation of cell killing (GO:0031342) | 3.95484806 |
| 29 | positive regulation of interferon-alpha production (GO:0032727) | 3.93592952 |
| 30 | cellular extravasation (GO:0045123) | 3.90495762 |
| 31 | myeloid leukocyte mediated immunity (GO:0002444) | 3.89660982 |
| 32 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.88850387 |
| 33 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.87363047 |
| 34 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.87307313 |
| 35 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.83810732 |
| 36 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.82097520 |
| 37 | regulation of interferon-alpha production (GO:0032647) | 3.69901519 |
| 38 | protein K48-linked deubiquitination (GO:0071108) | 3.64785244 |
| 39 | neutrophil mediated immunity (GO:0002446) | 3.59547763 |
| 40 | B cell receptor signaling pathway (GO:0050853) | 3.59103935 |
| 41 | hepatocyte apoptotic process (GO:0097284) | 3.57868877 |
| 42 | detection of other organism (GO:0098543) | 3.55310112 |
| 43 | protein K11-linked deubiquitination (GO:0035871) | 3.50761767 |
| 44 | response to type I interferon (GO:0034340) | 3.50538091 |
| 45 | detection of biotic stimulus (GO:0009595) | 3.44186693 |
| 46 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.43105741 |
| 47 | positive regulation of interferon-beta production (GO:0032728) | 3.42941525 |
| 48 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.40955448 |
| 49 | cellular response to type I interferon (GO:0071357) | 3.40315941 |
| 50 | type I interferon signaling pathway (GO:0060337) | 3.40315941 |
| 51 | negative T cell selection (GO:0043383) | 3.39837015 |
| 52 | myeloid cell activation involved in immune response (GO:0002275) | 3.37548716 |
| 53 | negative thymic T cell selection (GO:0045060) | 3.36934670 |
| 54 | regulation of necroptotic process (GO:0060544) | 3.31952383 |
| 55 | histone mRNA catabolic process (GO:0071044) | 3.30730951 |
| 56 | dosage compensation (GO:0007549) | 3.30170501 |
| 57 | response to peptidoglycan (GO:0032494) | 3.26761207 |
| 58 | protein K63-linked deubiquitination (GO:0070536) | 3.22130087 |
| 59 | T-helper 1 type immune response (GO:0042088) | 3.20356718 |
| 60 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.18504175 |
| 61 | neutrophil activation involved in immune response (GO:0002283) | 3.18147648 |
| 62 | positive T cell selection (GO:0043368) | 3.16418228 |
| 63 | T cell migration (GO:0072678) | 3.15483427 |
| 64 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.14971572 |
| 65 | immunoglobulin mediated immune response (GO:0016064) | 3.11576107 |
| 66 | positive thymic T cell selection (GO:0045059) | 3.10482275 |
| 67 | negative regulation of B cell mediated immunity (GO:0002713) | 3.10290898 |
| 68 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.10290898 |
| 69 | positive regulation of granulocyte differentiation (GO:0030854) | 3.08595617 |
| 70 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.07273530 |
| 71 | negative regulation of T cell mediated immunity (GO:0002710) | 3.06867462 |
| 72 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.06725598 |
| 73 | negative regulation of B cell proliferation (GO:0030889) | 3.04721150 |
| 74 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.04689744 |
| 75 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.04355328 |
| 76 | regulation of MHC class I biosynthetic process (GO:0045343) | 3.03991455 |
| 77 | defense response to protozoan (GO:0042832) | 3.01861755 |
| 78 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 3.00885367 |
| 79 | histone H3-K4 trimethylation (GO:0080182) | 2.94003982 |
| 80 | phagocytosis, recognition (GO:0006910) | 2.92021104 |
| 81 | regulation of interferon-beta production (GO:0032648) | 2.91738292 |
| 82 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.89336163 |
| 83 | establishment of protein localization to Golgi (GO:0072600) | 2.82006341 |
| 84 | interferon-gamma secretion (GO:0072643) | 2.80201948 |
| 85 | regulation of regulatory T cell differentiation (GO:0045589) | 2.80140721 |
| 86 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.79674061 |
| 87 | response to interferon-alpha (GO:0035455) | 2.79605219 |
| 88 | negative regulation of interleukin-17 production (GO:0032700) | 2.79276038 |
| 89 | eosinophil chemotaxis (GO:0048245) | 2.77705242 |
| 90 | detection of bacterium (GO:0016045) | 2.76881005 |
| 91 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.76736483 |
| 92 | negative regulation of complement activation (GO:0045916) | 2.75451768 |
| 93 | regulation of RIG-I signaling pathway (GO:0039535) | 2.75206625 |
| 94 | regulation of hypersensitivity (GO:0002883) | 2.74729858 |
| 95 | cytokine secretion (GO:0050663) | 2.74204930 |
| 96 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 2.70788095 |
| 97 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 2.70788095 |
| 98 | protein targeting to Golgi (GO:0000042) | 2.70340072 |
| 99 | B cell mediated immunity (GO:0019724) | 2.69223975 |
| 100 | necrotic cell death (GO:0070265) | 2.68298587 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.85868656 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.03347158 |
| 3 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 4.00369878 |
| 4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.97661899 |
| 5 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.96283872 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.53723977 |
| 7 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.25351366 |
| 8 | GATA1_22025678_ChIP-Seq_K562_Human | 3.05971686 |
| 9 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.94653517 |
| 10 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.93520848 |
| 11 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.85464614 |
| 12 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.77778709 |
| 13 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.69702985 |
| 14 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.69420959 |
| 15 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.56272012 |
| 16 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.38255798 |
| 17 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.23997066 |
| 18 | MYB_26560356_Chip-Seq_TH2_Human | 2.23098084 |
| 19 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.19652501 |
| 20 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.12705008 |
| 21 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.11378328 |
| 22 | SPI1_23127762_ChIP-Seq_K562_Human | 1.89402739 |
| 23 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.84769876 |
| 24 | MYB_26560356_Chip-Seq_TH1_Human | 1.80287641 |
| 25 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.78023450 |
| 26 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.68380081 |
| 27 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.61108897 |
| 28 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.56162092 |
| 29 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.53645735 |
| 30 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.51457054 |
| 31 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.51000089 |
| 32 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.48091907 |
| 33 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.46953299 |
| 34 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.45186591 |
| 35 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.40487939 |
| 36 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.38938982 |
| 37 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.38172716 |
| 38 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.37518936 |
| 39 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.36705590 |
| 40 | GATA3_26560356_Chip-Seq_TH2_Human | 1.34606755 |
| 41 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.33343611 |
| 42 | MAF_26560356_Chip-Seq_TH1_Human | 1.29889294 |
| 43 | TP53_16413492_ChIP-PET_HCT116_Human | 1.22721670 |
| 44 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.20933987 |
| 45 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.20917629 |
| 46 | GATA2_19941826_ChIP-Seq_K562_Human | 1.20435432 |
| 47 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.20265666 |
| 48 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.19757901 |
| 49 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.19417293 |
| 50 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.18856651 |
| 51 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.16931675 |
| 52 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.16486805 |
| 53 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.15629128 |
| 54 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.12692500 |
| 55 | GATA1_19941826_ChIP-Seq_K562_Human | 1.12260111 |
| 56 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.11018055 |
| 57 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.10901518 |
| 58 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.10369212 |
| 59 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 1.10302304 |
| 60 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.09472960 |
| 61 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.08940356 |
| 62 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.08854899 |
| 63 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.08686037 |
| 64 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.07600827 |
| 65 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.07048570 |
| 66 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.02927173 |
| 67 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.02792161 |
| 68 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.02127786 |
| 69 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.96676780 |
| 70 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.95990172 |
| 71 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.95494475 |
| 72 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 0.95236928 |
| 73 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.94546900 |
| 74 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.93193419 |
| 75 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92979062 |
| 76 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.92919090 |
| 77 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.92261732 |
| 78 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92261732 |
| 79 | STAT3_23295773_ChIP-Seq_U87_Human | 0.92066519 |
| 80 | UTX_26944678_Chip-Seq_JUKART_Human | 0.91831189 |
| 81 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.91499942 |
| 82 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.91152049 |
| 83 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.90406050 |
| 84 | MAF_26560356_Chip-Seq_TH2_Human | 0.89219968 |
| 85 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.86304264 |
| 86 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.86002614 |
| 87 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.85651536 |
| 88 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.84814280 |
| 89 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.84734636 |
| 90 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.84673860 |
| 91 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.84663792 |
| 92 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.83781691 |
| 93 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.79477094 |
| 94 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.79477094 |
| 95 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.78644527 |
| 96 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.78031798 |
| 97 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.77784457 |
| 98 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.77123853 |
| 99 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.77052732 |
| 100 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.76923535 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000569_abnormal_digit_pigmentation | 6.65940329 |
| 2 | MP0003724_increased_susceptibility_to | 4.54965505 |
| 3 | MP0008260_abnormal_autophagy | 3.92591326 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.65559269 |
| 5 | MP0003787_abnormal_imprinting | 2.67214113 |
| 6 | MP0003172_abnormal_lysosome_physiology | 2.60089648 |
| 7 | MP0003656_abnormal_erythrocyte_physiolo | 2.49759398 |
| 8 | MP0001800_abnormal_humoral_immune | 2.49655741 |
| 9 | MP0005174_abnormal_tail_pigmentation | 2.43963158 |
| 10 | MP0009785_altered_susceptibility_to | 2.35210221 |
| 11 | MP0000015_abnormal_ear_pigmentation | 2.33266361 |
| 12 | MP0000685_abnormal_immune_system | 2.32473621 |
| 13 | MP0005451_abnormal_body_composition | 2.28688251 |
| 14 | MP0008877_abnormal_DNA_methylation | 2.23864748 |
| 15 | MP0008057_abnormal_DNA_replication | 2.19563452 |
| 16 | MP0004381_abnormal_hair_follicle | 2.17391072 |
| 17 | MP0003303_peritoneal_inflammation | 2.15967882 |
| 18 | MP0002419_abnormal_innate_immunity | 2.10699649 |
| 19 | MP0002166_altered_tumor_susceptibility | 2.06719654 |
| 20 | MP0006082_CNS_inflammation | 2.05396926 |
| 21 | MP0002452_abnormal_antigen_presenting | 2.01947444 |
| 22 | MP0005025_abnormal_response_to | 2.01894462 |
| 23 | MP0002723_abnormal_immune_serum | 2.01351985 |
| 24 | MP0005000_abnormal_immune_tolerance | 2.00064459 |
| 25 | MP0004883_abnormal_blood_vessel | 1.99357891 |
| 26 | MP0003221_abnormal_cardiomyocyte_apopto | 1.97364392 |
| 27 | MP0005310_abnormal_salivary_gland | 1.92394498 |
| 28 | MP0005671_abnormal_response_to | 1.89143026 |
| 29 | MP0005387_immune_system_phenotype | 1.87383806 |
| 30 | MP0001790_abnormal_immune_system | 1.87383806 |
| 31 | MP0003191_abnormal_cellular_cholesterol | 1.83307838 |
| 32 | MP0002420_abnormal_adaptive_immunity | 1.82045688 |
| 33 | MP0001819_abnormal_immune_cell | 1.80599177 |
| 34 | MP0003436_decreased_susceptibility_to | 1.78904720 |
| 35 | MP0002148_abnormal_hypersensitivity_rea | 1.71179531 |
| 36 | MP0003763_abnormal_thymus_physiology | 1.68351184 |
| 37 | MP0002332_abnormal_exercise_endurance | 1.63676126 |
| 38 | MP0002398_abnormal_bone_marrow | 1.57487437 |
| 39 | MP0005164_abnormal_response_to | 1.55327289 |
| 40 | MP0003183_abnormal_peptide_metabolism | 1.53665842 |
| 41 | MP0000716_abnormal_immune_system | 1.52459440 |
| 42 | MP0004484_altered_response_of | 1.51278984 |
| 43 | MP0002396_abnormal_hematopoietic_system | 1.48456276 |
| 44 | MP0005075_abnormal_melanosome_morpholog | 1.46380585 |
| 45 | MP0002006_tumorigenesis | 1.40781588 |
| 46 | MP0005464_abnormal_platelet_physiology | 1.40542769 |
| 47 | MP0003828_pulmonary_edema | 1.37681600 |
| 48 | MP0003690_abnormal_glial_cell | 1.37273519 |
| 49 | MP0002405_respiratory_system_inflammati | 1.36881953 |
| 50 | MP0001545_abnormal_hematopoietic_system | 1.33665914 |
| 51 | MP0005397_hematopoietic_system_phenotyp | 1.33665914 |
| 52 | MP0004808_abnormal_hematopoietic_stem | 1.33417345 |
| 53 | MP0000689_abnormal_spleen_morphology | 1.29881160 |
| 54 | MP0002722_abnormal_immune_system | 1.27860559 |
| 55 | MP0001845_abnormal_inflammatory_respons | 1.27674909 |
| 56 | MP0004947_skin_inflammation | 1.26694023 |
| 57 | MP0003632_abnormal_nervous_system | 1.26550323 |
| 58 | MP0003300_gastrointestinal_ulcer | 1.21157170 |
| 59 | MP0006054_spinal_hemorrhage | 1.20799299 |
| 60 | MP0002429_abnormal_blood_cell | 1.17039770 |
| 61 | MP0003091_abnormal_cell_migration | 1.14949584 |
| 62 | MP0000703_abnormal_thymus_morphology | 1.13714547 |
| 63 | MP0009764_decreased_sensitivity_to | 1.13525247 |
| 64 | MP0009278_abnormal_bone_marrow | 1.10022197 |
| 65 | MP0001533_abnormal_skeleton_physiology | 1.07279659 |
| 66 | MP0000604_amyloidosis | 1.07132767 |
| 67 | MP0004130_abnormal_muscle_cell | 0.99633241 |
| 68 | MP0005076_abnormal_cell_differentiation | 0.97904005 |
| 69 | MP0000371_diluted_coat_color | 0.97714532 |
| 70 | MP0003646_muscle_fatigue | 0.93030436 |
| 71 | MP0000858_altered_metastatic_potential | 0.92888345 |
| 72 | MP0002277_abnormal_respiratory_mucosa | 0.92474974 |
| 73 | MP0008469_abnormal_protein_level | 0.90680038 |
| 74 | MP0003866_abnormal_defecation | 0.86106973 |
| 75 | MP0002009_preneoplasia | 0.85315473 |
| 76 | MP0002909_abnormal_adrenal_gland | 0.85297830 |
| 77 | MP0000427_abnormal_hair_cycle | 0.84662419 |
| 78 | MP0003195_calcinosis | 0.83832780 |
| 79 | MP0005376_homeostasis/metabolism_phenot | 0.82857165 |
| 80 | MP0010155_abnormal_intestine_physiology | 0.81869424 |
| 81 | MP0005266_abnormal_metabolism | 0.78329261 |
| 82 | MP0009765_abnormal_xenobiotic_induced | 0.77943071 |
| 83 | MP0002132_abnormal_respiratory_system | 0.76868323 |
| 84 | MP0009763_increased_sensitivity_to | 0.76430174 |
| 85 | MP0002998_abnormal_bone_remodeling | 0.74107677 |
| 86 | MP0008874_decreased_physiological_sensi | 0.74015214 |
| 87 | MP0010307_abnormal_tumor_latency | 0.72112856 |
| 88 | MP0005621_abnormal_cell_physiology | 0.69265480 |
| 89 | MP0003121_genomic_imprinting | 0.68175161 |
| 90 | MP0001851_eye_inflammation | 0.67278529 |
| 91 | MP0000249_abnormal_blood_vessel | 0.67084234 |
| 92 | MP0004043_abnormal_pH_regulation | 0.66643047 |
| 93 | MP0003045_fibrosis | 0.66075389 |
| 94 | MP0003631_nervous_system_phenotype | 0.65534848 |
| 95 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.64514544 |
| 96 | MP0003329_amyloid_beta_deposits | 0.62792226 |
| 97 | MP0003448_altered_tumor_morphology | 0.62546575 |
| 98 | MP0005410_abnormal_fertilization | 0.62251319 |
| 99 | MP0002019_abnormal_tumor_incidence | 0.61928891 |
| 100 | MP0005409_darkened_coat_color | 0.61666931 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Recurrent bacterial skin infections (HP:0005406) | 6.61182654 |
| 2 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 6.41767644 |
| 3 | Recurrent abscess formation (HP:0002722) | 5.41299012 |
| 4 | Postural instability (HP:0002172) | 4.64646302 |
| 5 | T lymphocytopenia (HP:0005403) | 4.62536883 |
| 6 | Abnormality of T cell number (HP:0011839) | 4.57938667 |
| 7 | Retrobulbar optic neuritis (HP:0100654) | 4.54665011 |
| 8 | Optic neuritis (HP:0100653) | 4.54665011 |
| 9 | Gastrointestinal infarctions (HP:0005244) | 4.43401574 |
| 10 | Recurrent skin infections (HP:0001581) | 4.29837131 |
| 11 | Eczematoid dermatitis (HP:0000976) | 4.24665827 |
| 12 | Orchitis (HP:0100796) | 4.10999295 |
| 13 | Recurrent cutaneous fungal infections (HP:0011370) | 4.10086604 |
| 14 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.10086604 |
| 15 | Gingivitis (HP:0000230) | 4.04923757 |
| 16 | Peritonitis (HP:0002586) | 3.98765849 |
| 17 | Recurrent fungal infections (HP:0002841) | 3.95781318 |
| 18 | Myositis (HP:0100614) | 3.91570147 |
| 19 | Genetic anticipation (HP:0003743) | 3.87522870 |
| 20 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.56844140 |
| 21 | Resting tremor (HP:0002322) | 3.41474893 |
| 22 | Visual hallucinations (HP:0002367) | 3.34284233 |
| 23 | Gingival bleeding (HP:0000225) | 3.28171345 |
| 24 | Arterial thrombosis (HP:0004420) | 3.22844441 |
| 25 | Keratoconjunctivitis sicca (HP:0001097) | 3.15460446 |
| 26 | Recurrent viral infections (HP:0004429) | 3.10543366 |
| 27 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.02240035 |
| 28 | Periodontitis (HP:0000704) | 3.01633446 |
| 29 | Abnormality of T cells (HP:0002843) | 2.99165573 |
| 30 | Encephalitis (HP:0002383) | 2.97606959 |
| 31 | Slow saccadic eye movements (HP:0000514) | 2.83136454 |
| 32 | Keratoconjunctivitis (HP:0001096) | 2.80938202 |
| 33 | Mediastinal lymphadenopathy (HP:0100721) | 2.80198414 |
| 34 | Stomatitis (HP:0010280) | 2.75632673 |
| 35 | Meningitis (HP:0001287) | 2.75078257 |
| 36 | Hemoptysis (HP:0002105) | 2.73563057 |
| 37 | Abnormality of the fingertips (HP:0001211) | 2.70380031 |
| 38 | Chest pain (HP:0100749) | 2.65465947 |
| 39 | Progressive cerebellar ataxia (HP:0002073) | 2.61890334 |
| 40 | Viral hepatitis (HP:0006562) | 2.61760010 |
| 41 | Colitis (HP:0002583) | 2.60890359 |
| 42 | Inflammation of the large intestine (HP:0002037) | 2.58938295 |
| 43 | Recurrent bronchitis (HP:0002837) | 2.53850193 |
| 44 | Gaze-evoked nystagmus (HP:0000640) | 2.51729541 |
| 45 | Acute hepatic failure (HP:0006554) | 2.51152133 |
| 46 | Abnormality of macrophages (HP:0004311) | 2.50336462 |
| 47 | Leukocytosis (HP:0001974) | 2.49853005 |
| 48 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.49285453 |
| 49 | Vasculitis (HP:0002633) | 2.47257556 |
| 50 | Spontaneous hematomas (HP:0007420) | 2.47086912 |
| 51 | Abnormality of the peritoneum (HP:0002585) | 2.45395505 |
| 52 | Autoimmune thrombocytopenia (HP:0001973) | 2.44551881 |
| 53 | Acute myeloid leukemia (HP:0004808) | 2.42897984 |
| 54 | Autoimmune hemolytic anemia (HP:0001890) | 2.41145965 |
| 55 | Poikilocytosis (HP:0004447) | 2.40644978 |
| 56 | Pustule (HP:0200039) | 2.35265122 |
| 57 | Panhypogammaglobulinemia (HP:0003139) | 2.32821203 |
| 58 | Gastrointestinal inflammation (HP:0004386) | 2.31079919 |
| 59 | Urticaria (HP:0001025) | 2.29575776 |
| 60 | Epistaxis (HP:0000421) | 2.28417757 |
| 61 | Eosinophilia (HP:0001880) | 2.26290360 |
| 62 | Dysmetric saccades (HP:0000641) | 2.19953748 |
| 63 | Abnormality of the endocardium (HP:0004306) | 2.18565780 |
| 64 | Subacute progressive viral hepatitis (HP:0006572) | 2.17886157 |
| 65 | Pulmonary infiltrates (HP:0002113) | 2.14854417 |
| 66 | Cellulitis (HP:0100658) | 2.13140066 |
| 67 | IgA deficiency (HP:0002720) | 2.09079326 |
| 68 | Truncal obesity (HP:0001956) | 2.08829629 |
| 69 | Abnormality of T cell physiology (HP:0011840) | 2.08518251 |
| 70 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.07712544 |
| 71 | Chronic otitis media (HP:0000389) | 2.07633216 |
| 72 | Cheilitis (HP:0100825) | 2.06444341 |
| 73 | Anorexia (HP:0002039) | 2.05814802 |
| 74 | Cerebral inclusion bodies (HP:0100314) | 2.01121850 |
| 75 | Gangrene (HP:0100758) | 1.93795155 |
| 76 | Chronic obstructive pulmonary disease (HP:0006510) | 1.93267990 |
| 77 | Obstructive lung disease (HP:0006536) | 1.93267990 |
| 78 | Granulocytopenia (HP:0001913) | 1.92901187 |
| 79 | Ocular albinism (HP:0001107) | 1.91482999 |
| 80 | Tinnitus (HP:0000360) | 1.88156409 |
| 81 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.86625304 |
| 82 | Fatigue (HP:0012378) | 1.86192943 |
| 83 | Pulmonary embolism (HP:0002204) | 1.86023553 |
| 84 | Stomach cancer (HP:0012126) | 1.84753862 |
| 85 | Prolonged bleeding time (HP:0003010) | 1.84503177 |
| 86 | Bradykinesia (HP:0002067) | 1.83703309 |
| 87 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.81920203 |
| 88 | Prominent nose (HP:0000448) | 1.81135159 |
| 89 | Abnormality of eosinophils (HP:0001879) | 1.79443344 |
| 90 | Amyotrophic lateral sclerosis (HP:0007354) | 1.77242358 |
| 91 | Osteomyelitis (HP:0002754) | 1.75525489 |
| 92 | Hyperkalemia (HP:0002153) | 1.71797840 |
| 93 | Keratitis (HP:0000491) | 1.71791031 |
| 94 | Dysautonomia (HP:0002459) | 1.70699034 |
| 95 | Chronic diarrhea (HP:0002028) | 1.70133888 |
| 96 | Absent speech (HP:0001344) | 1.70060241 |
| 97 | Papillary thyroid carcinoma (HP:0002895) | 1.68266802 |
| 98 | Choroideremia (HP:0001139) | 1.68023234 |
| 99 | Conjunctival telangiectasia (HP:0000524) | 1.67948033 |
| 100 | Myocardial infarction (HP:0001658) | 1.67656589 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BLK | 5.22478855 |
| 2 | RIPK4 | 3.39546388 |
| 3 | FGR | 2.46117700 |
| 4 | IKBKE | 2.43651898 |
| 5 | FRK | 2.38085212 |
| 6 | JAK1 | 2.31683395 |
| 7 | GRK6 | 2.27406492 |
| 8 | IRAK4 | 2.23218366 |
| 9 | CSK | 2.19512626 |
| 10 | JAK3 | 2.09610997 |
| 11 | PIK3CG | 2.08722729 |
| 12 | WNK1 | 2.06034124 |
| 13 | CDK12 | 2.04453955 |
| 14 | TYK2 | 1.95618591 |
| 15 | MAP3K14 | 1.93458757 |
| 16 | TXK | 1.92230144 |
| 17 | SYK | 1.89447197 |
| 18 | PTK2B | 1.75046892 |
| 19 | MAP2K3 | 1.69321723 |
| 20 | FES | 1.65198690 |
| 21 | FGFR3 | 1.61991310 |
| 22 | ACVR1B | 1.60697351 |
| 23 | BMPR2 | 1.57188730 |
| 24 | MAP4K1 | 1.53457559 |
| 25 | MAP3K6 | 1.52387417 |
| 26 | MAP3K2 | 1.48495632 |
| 27 | BTK | 1.46764096 |
| 28 | TAOK3 | 1.45431437 |
| 29 | TEC | 1.45153598 |
| 30 | SGK2 | 1.41396574 |
| 31 | IRAK1 | 1.38919018 |
| 32 | STK4 | 1.31565266 |
| 33 | JAK2 | 1.29198738 |
| 34 | ERBB2 | 1.27395416 |
| 35 | GRK5 | 1.22829459 |
| 36 | LYN | 1.20398726 |
| 37 | CAMK1D | 1.20213354 |
| 38 | KSR1 | 1.16539224 |
| 39 | ITK | 1.15952910 |
| 40 | CAMK1G | 1.14393720 |
| 41 | ZAP70 | 1.12815166 |
| 42 | KIT | 1.12420722 |
| 43 | HCK | 1.07367966 |
| 44 | PLK2 | 1.05795786 |
| 45 | FGFR4 | 1.05395111 |
| 46 | YES1 | 1.01527633 |
| 47 | SGK3 | 0.98470440 |
| 48 | MAP3K1 | 0.98254952 |
| 49 | IRAK2 | 0.97078003 |
| 50 | TRPM7 | 0.96272178 |
| 51 | MAP3K13 | 0.96033242 |
| 52 | LCK | 0.90614257 |
| 53 | LRRK2 | 0.90075624 |
| 54 | TBK1 | 0.89851859 |
| 55 | EPHA3 | 0.89511735 |
| 56 | CAMKK2 | 0.85935625 |
| 57 | IKBKB | 0.84101952 |
| 58 | CSF1R | 0.83450672 |
| 59 | NLK | 0.82996462 |
| 60 | BCR | 0.82840895 |
| 61 | AKT3 | 0.80638033 |
| 62 | PKN2 | 0.80363403 |
| 63 | CDC42BPA | 0.79049400 |
| 64 | KSR2 | 0.77345572 |
| 65 | SGK223 | 0.76142397 |
| 66 | SGK494 | 0.76142397 |
| 67 | MARK2 | 0.75747492 |
| 68 | PIM1 | 0.74107391 |
| 69 | CHUK | 0.72464481 |
| 70 | MATK | 0.70086600 |
| 71 | NEK6 | 0.65191954 |
| 72 | SGK1 | 0.63219839 |
| 73 | BRD4 | 0.60041267 |
| 74 | TNK2 | 0.59264393 |
| 75 | MARK3 | 0.58761932 |
| 76 | STK38 | 0.57729280 |
| 77 | MAP3K5 | 0.57436093 |
| 78 | RET | 0.55197033 |
| 79 | EGFR | 0.55095753 |
| 80 | BMPR1B | 0.54539936 |
| 81 | EPHB1 | 0.53407390 |
| 82 | MAP2K4 | 0.53205677 |
| 83 | RAF1 | 0.52623839 |
| 84 | MELK | 0.52139440 |
| 85 | DYRK1A | 0.50204909 |
| 86 | CLK1 | 0.48052815 |
| 87 | ADRBK1 | 0.47711967 |
| 88 | PDK1 | 0.47466168 |
| 89 | CDK4 | 0.46317721 |
| 90 | PRKAA2 | 0.45557763 |
| 91 | CAMK4 | 0.45421782 |
| 92 | TRIB3 | 0.42910234 |
| 93 | FYN | 0.41655531 |
| 94 | STK11 | 0.40717224 |
| 95 | MAP2K6 | 0.39406384 |
| 96 | CDK6 | 0.38883292 |
| 97 | NEK9 | 0.37675824 |
| 98 | MAP3K4 | 0.37212731 |
| 99 | PDGFRB | 0.37051129 |
| 100 | CDK3 | 0.36092075 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Leishmaniasis_Homo sapiens_hsa05140 | 3.06477450 |
| 2 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.74735966 |
| 3 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.33122192 |
| 4 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.25141013 |
| 5 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.23839162 |
| 6 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.20570470 |
| 7 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.17007152 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.13699158 |
| 9 | Tuberculosis_Homo sapiens_hsa05152 | 2.05429233 |
| 10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.97387623 |
| 11 | Allograft rejection_Homo sapiens_hsa05330 | 1.95440796 |
| 12 | Influenza A_Homo sapiens_hsa05164 | 1.92910472 |
| 13 | Measles_Homo sapiens_hsa05162 | 1.90995982 |
| 14 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.83574016 |
| 15 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.82020722 |
| 16 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.80508612 |
| 17 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.77230206 |
| 18 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.73756641 |
| 19 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.62086264 |
| 20 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.60836888 |
| 21 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.58922817 |
| 22 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.56091478 |
| 23 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.51666834 |
| 24 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.48151553 |
| 25 | Malaria_Homo sapiens_hsa05144 | 1.45307806 |
| 26 | Legionellosis_Homo sapiens_hsa05134 | 1.42718277 |
| 27 | Asthma_Homo sapiens_hsa05310 | 1.40962574 |
| 28 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.40846586 |
| 29 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.39913395 |
| 30 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.37367203 |
| 31 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.37268482 |
| 32 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.36290599 |
| 33 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.30080455 |
| 34 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.27670406 |
| 35 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.26684228 |
| 36 | Hepatitis C_Homo sapiens_hsa05160 | 1.25601097 |
| 37 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.20693233 |
| 38 | Hepatitis B_Homo sapiens_hsa05161 | 1.19967107 |
| 39 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.16454053 |
| 40 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.14477500 |
| 41 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.13204583 |
| 42 | Platelet activation_Homo sapiens_hsa04611 | 1.11907448 |
| 43 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.11321543 |
| 44 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.06255210 |
| 45 | Phagosome_Homo sapiens_hsa04145 | 1.04026666 |
| 46 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.02906943 |
| 47 | Viral myocarditis_Homo sapiens_hsa05416 | 1.02445522 |
| 48 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.01593650 |
| 49 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.93533642 |
| 50 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.92582351 |
| 51 | Apoptosis_Homo sapiens_hsa04210 | 0.91952131 |
| 52 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.89085013 |
| 53 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.85083138 |
| 54 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.83276709 |
| 55 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.81800359 |
| 56 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.81264921 |
| 57 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.80351188 |
| 58 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.79914243 |
| 59 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.78810394 |
| 60 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.75587687 |
| 61 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.73207780 |
| 62 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.71544265 |
| 63 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.69935502 |
| 64 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.69572848 |
| 65 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.66716889 |
| 66 | Endometrial cancer_Homo sapiens_hsa05213 | 0.66657513 |
| 67 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.64853541 |
| 68 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.64507501 |
| 69 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.64374768 |
| 70 | Insulin resistance_Homo sapiens_hsa04931 | 0.62151935 |
| 71 | ABC transporters_Homo sapiens_hsa02010 | 0.61934693 |
| 72 | Pertussis_Homo sapiens_hsa05133 | 0.59807155 |
| 73 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.57806118 |
| 74 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.55796643 |
| 75 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.55761506 |
| 76 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.55464665 |
| 77 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.55191049 |
| 78 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.54044163 |
| 79 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.52668042 |
| 80 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.52628646 |
| 81 | Prostate cancer_Homo sapiens_hsa05215 | 0.52135798 |
| 82 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.51869166 |
| 83 | Lysine degradation_Homo sapiens_hsa00310 | 0.51074229 |
| 84 | Glioma_Homo sapiens_hsa05214 | 0.50291784 |
| 85 | Shigellosis_Homo sapiens_hsa05131 | 0.50145456 |
| 86 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.49599545 |
| 87 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.47881502 |
| 88 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.47226705 |
| 89 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.46559783 |
| 90 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.46141903 |
| 91 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.44334700 |
| 92 | Long-term potentiation_Homo sapiens_hsa04720 | 0.43584067 |
| 93 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.42495863 |
| 94 | Circadian rhythm_Homo sapiens_hsa04710 | 0.42210069 |
| 95 | Salmonella infection_Homo sapiens_hsa05132 | 0.41623020 |
| 96 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.40232409 |
| 97 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.39824913 |
| 98 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.38882809 |
| 99 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.38323449 |
| 100 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.38141470 |

