

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cellular response to cadmium ion (GO:0071276) | 5.98712356 |
| 2 | synaptic vesicle exocytosis (GO:0016079) | 5.60836403 |
| 3 | central nervous system myelination (GO:0022010) | 5.44924179 |
| 4 | axon ensheathment in central nervous system (GO:0032291) | 5.44924179 |
| 5 | glutamate secretion (GO:0014047) | 5.34258423 |
| 6 | regulation of response to food (GO:0032095) | 5.20244731 |
| 7 | cellular response to nitric oxide (GO:0071732) | 5.19827327 |
| 8 | cellular potassium ion homeostasis (GO:0030007) | 5.19394637 |
| 9 | potassium ion homeostasis (GO:0055075) | 5.06349082 |
| 10 | potassium ion import (GO:0010107) | 5.06324761 |
| 11 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 5.03062217 |
| 12 | cellular response to leptin stimulus (GO:0044320) | 4.99134252 |
| 13 | response to leptin (GO:0044321) | 4.86249628 |
| 14 | regulation of protein glycosylation (GO:0060049) | 4.81001984 |
| 15 | regulation of female receptivity (GO:0045924) | 4.54706951 |
| 16 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 4.39438359 |
| 17 | cholesterol catabolic process (GO:0006707) | 4.19707785 |
| 18 | sterol catabolic process (GO:0016127) | 4.19707785 |
| 19 | regulation of oxidative phosphorylation (GO:0002082) | 4.04750016 |
| 20 | gamma-aminobutyric acid transport (GO:0015812) | 4.04456630 |
| 21 | cellular response to zinc ion (GO:0071294) | 3.98057142 |
| 22 | neurotransmitter secretion (GO:0007269) | 3.97453439 |
| 23 | cellular response to reactive nitrogen species (GO:1902170) | 3.95090398 |
| 24 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.92918099 |
| 25 | female mating behavior (GO:0060180) | 3.92249812 |
| 26 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.89392008 |
| 27 | regulation of sensory perception of pain (GO:0051930) | 3.86458479 |
| 28 | regulation of sensory perception (GO:0051931) | 3.86458479 |
| 29 | response to nitric oxide (GO:0071731) | 3.81878197 |
| 30 | neurotransmitter uptake (GO:0001504) | 3.80066575 |
| 31 | postsynaptic membrane organization (GO:0001941) | 3.74281621 |
| 32 | L-amino acid import (GO:0043092) | 3.70838857 |
| 33 | negative regulation of response to food (GO:0032096) | 3.65840662 |
| 34 | negative regulation of appetite (GO:0032099) | 3.65840662 |
| 35 | cellular zinc ion homeostasis (GO:0006882) | 3.63259007 |
| 36 | cellular response to superoxide (GO:0071451) | 3.62655515 |
| 37 | cellular response to oxygen radical (GO:0071450) | 3.62655515 |
| 38 | removal of superoxide radicals (GO:0019430) | 3.62655515 |
| 39 | auditory behavior (GO:0031223) | 3.61417613 |
| 40 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.55228839 |
| 41 | regulation of synapse structural plasticity (GO:0051823) | 3.53310963 |
| 42 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.48808883 |
| 43 | calcium ion-dependent exocytosis (GO:0017156) | 3.42415478 |
| 44 | activation of protein kinase B activity (GO:0032148) | 3.41484100 |
| 45 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 3.41291515 |
| 46 | respiratory electron transport chain (GO:0022904) | 3.39969946 |
| 47 | positive regulation of synapse maturation (GO:0090129) | 3.35716875 |
| 48 | sleep (GO:0030431) | 3.34904625 |
| 49 | detection of calcium ion (GO:0005513) | 3.34794342 |
| 50 | cellular response to electrical stimulus (GO:0071257) | 3.34586570 |
| 51 | electron transport chain (GO:0022900) | 3.34436622 |
| 52 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 3.31943841 |
| 53 | astrocyte development (GO:0014002) | 3.31403375 |
| 54 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.29645916 |
| 55 | regulation of cell communication by electrical coupling (GO:0010649) | 3.25509896 |
| 56 | positive regulation of dendritic spine development (GO:0060999) | 3.24656536 |
| 57 | insulin secretion (GO:0030073) | 3.24575085 |
| 58 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.24062106 |
| 59 | regulation of neurotransmitter levels (GO:0001505) | 3.23492593 |
| 60 | positive regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030949) | 3.23119668 |
| 61 | negative regulation of reactive oxygen species metabolic process (GO:2000378) | 3.21966868 |
| 62 | response to histamine (GO:0034776) | 3.21489533 |
| 63 | sodium ion export (GO:0071436) | 3.20008267 |
| 64 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.18967524 |
| 65 | neurotransmitter transport (GO:0006836) | 3.15405552 |
| 66 | membrane repolarization (GO:0086009) | 3.14607265 |
| 67 | cAMP-mediated signaling (GO:0019933) | 3.12981389 |
| 68 | zinc ion homeostasis (GO:0055069) | 3.12832611 |
| 69 | ATP synthesis coupled proton transport (GO:0015986) | 3.10684191 |
| 70 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.10684191 |
| 71 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.06983326 |
| 72 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.00315193 |
| 73 | positive regulation of potassium ion transport (GO:0043268) | 2.98688671 |
| 74 | substrate-independent telencephalic tangential migration (GO:0021826) | 2.98400023 |
| 75 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 2.98400023 |
| 76 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.96505310 |
| 77 | neurofilament cytoskeleton organization (GO:0060052) | 2.92985823 |
| 78 | positive regulation of meiosis (GO:0045836) | 2.92900185 |
| 79 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.90908742 |
| 80 | negative regulation of necrotic cell death (GO:0060547) | 2.90300637 |
| 81 | response to superoxide (GO:0000303) | 2.90117649 |
| 82 | response to auditory stimulus (GO:0010996) | 2.87974820 |
| 83 | membrane hyperpolarization (GO:0060081) | 2.86564403 |
| 84 | synaptic vesicle maturation (GO:0016188) | 2.85018645 |
| 85 | startle response (GO:0001964) | 2.84496836 |
| 86 | steroid catabolic process (GO:0006706) | 2.79407804 |
| 87 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.79347736 |
| 88 | amino acid import (GO:0043090) | 2.78552505 |
| 89 | relaxation of smooth muscle (GO:0044557) | 2.78506491 |
| 90 | glutamate receptor signaling pathway (GO:0007215) | 2.78460397 |
| 91 | cellular sodium ion homeostasis (GO:0006883) | 2.77201643 |
| 92 | regulation of synapse maturation (GO:0090128) | 2.77104647 |
| 93 | regulation of cellular respiration (GO:0043457) | 2.77084208 |
| 94 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 2.76263561 |
| 95 | L-phenylalanine catabolic process (GO:0006559) | 2.76263561 |
| 96 | one-carbon compound transport (GO:0019755) | 2.74142388 |
| 97 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.73345944 |
| 98 | synaptic transmission, glutamatergic (GO:0035249) | 2.72656174 |
| 99 | urinary tract smooth muscle contraction (GO:0014848) | 2.72271642 |
| 100 | transmission of nerve impulse (GO:0019226) | 2.70995897 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 7.01442430 |
| 2 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.76690031 |
| 3 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.63104430 |
| 4 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.62242470 |
| 5 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.57797561 |
| 6 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.55265456 |
| 7 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.46953825 |
| 8 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.45756444 |
| 9 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.33347784 |
| 10 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.25921661 |
| 11 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.24078957 |
| 12 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.18577425 |
| 13 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.13339847 |
| 14 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.11849076 |
| 15 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.02580615 |
| 16 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.00946505 |
| 17 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.00926047 |
| 18 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.98696744 |
| 19 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.95980292 |
| 20 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.91065017 |
| 21 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.91043342 |
| 22 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.91043342 |
| 23 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.89641220 |
| 24 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.89393207 |
| 25 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.86514747 |
| 26 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.84984615 |
| 27 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.78837899 |
| 28 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.76875944 |
| 29 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.73014666 |
| 30 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.69654307 |
| 31 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.68658767 |
| 32 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.58367146 |
| 33 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.57864216 |
| 34 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.52240565 |
| 35 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.44834482 |
| 36 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.36891849 |
| 37 | P300_19829295_ChIP-Seq_ESCs_Human | 1.34242434 |
| 38 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.34119039 |
| 39 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.33056225 |
| 40 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.32146183 |
| 41 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.30084246 |
| 42 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.24991015 |
| 43 | AR_25329375_ChIP-Seq_VCAP_Human | 1.24220497 |
| 44 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.19437160 |
| 45 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.17363322 |
| 46 | TCF4_23295773_ChIP-Seq_U87_Human | 1.16450407 |
| 47 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.14906965 |
| 48 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.13619841 |
| 49 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.13485757 |
| 50 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.12321980 |
| 51 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.11049711 |
| 52 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.09397512 |
| 53 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.09201968 |
| 54 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.08222315 |
| 55 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.08061586 |
| 56 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.07689934 |
| 57 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.07177325 |
| 58 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.06887772 |
| 59 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.05189505 |
| 60 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.05186668 |
| 61 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.04586267 |
| 62 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.04449657 |
| 63 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.04322229 |
| 64 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.04146205 |
| 65 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.01018561 |
| 66 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.01018561 |
| 67 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.98905229 |
| 68 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.97944536 |
| 69 | FUS_26573619_Chip-Seq_HEK293_Human | 0.97765985 |
| 70 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.96991269 |
| 71 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.96928532 |
| 72 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.96522973 |
| 73 | VDR_22108803_ChIP-Seq_LS180_Human | 0.96356104 |
| 74 | STAT3_23295773_ChIP-Seq_U87_Human | 0.95077874 |
| 75 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.93858552 |
| 76 | AR_19668381_ChIP-Seq_PC3_Human | 0.93738682 |
| 77 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.90964004 |
| 78 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.90326272 |
| 79 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.89212682 |
| 80 | RXR_22108803_ChIP-Seq_LS180_Human | 0.89140215 |
| 81 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.89066466 |
| 82 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.89034730 |
| 83 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.88678641 |
| 84 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.88177439 |
| 85 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.87309879 |
| 86 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.86752168 |
| 87 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.86559362 |
| 88 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.86559362 |
| 89 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.85657312 |
| 90 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.85064061 |
| 91 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.85000975 |
| 92 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.84878476 |
| 93 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.84056566 |
| 94 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.84027229 |
| 95 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.83568820 |
| 96 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.83227651 |
| 97 | JUN_21703547_ChIP-Seq_K562_Human | 0.83022857 |
| 98 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.82786229 |
| 99 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.82731349 |
| 100 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.82475559 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004885_abnormal_endolymph | 4.23732827 |
| 2 | MP0003880_abnormal_central_pattern | 3.87456772 |
| 3 | MP0004043_abnormal_pH_regulation | 3.81413448 |
| 4 | MP0004859_abnormal_synaptic_plasticity | 3.77097242 |
| 5 | MP0003787_abnormal_imprinting | 3.63739297 |
| 6 | MP0002064_seizures | 3.17614961 |
| 7 | MP0003635_abnormal_synaptic_transmissio | 2.93380519 |
| 8 | MP0009379_abnormal_foot_pigmentation | 2.88636511 |
| 9 | MP0004270_analgesia | 2.83962842 |
| 10 | MP0009780_abnormal_chondrocyte_physiolo | 2.82092977 |
| 11 | MP0009745_abnormal_behavioral_response | 2.78445420 |
| 12 | MP0002272_abnormal_nervous_system | 2.65886333 |
| 13 | MP0008877_abnormal_DNA_methylation | 2.48244175 |
| 14 | MP0005646_abnormal_pituitary_gland | 2.47055203 |
| 15 | MP0001485_abnormal_pinna_reflex | 2.41996480 |
| 16 | MP0001486_abnormal_startle_reflex | 2.34107191 |
| 17 | MP0003879_abnormal_hair_cell | 2.07828390 |
| 18 | MP0001501_abnormal_sleep_pattern | 2.07477993 |
| 19 | MP0009046_muscle_twitch | 2.04596630 |
| 20 | MP0002063_abnormal_learning/memory/cond | 2.04225184 |
| 21 | MP0001968_abnormal_touch/_nociception | 2.01492491 |
| 22 | MP0002734_abnormal_mechanical_nocicepti | 1.99273676 |
| 23 | MP0002572_abnormal_emotion/affect_behav | 1.89142498 |
| 24 | MP0005423_abnormal_somatic_nervous | 1.87066516 |
| 25 | MP0001440_abnormal_grooming_behavior | 1.84483800 |
| 26 | MP0001905_abnormal_dopamine_level | 1.82649950 |
| 27 | MP0005551_abnormal_eye_electrophysiolog | 1.76360667 |
| 28 | MP0001970_abnormal_pain_threshold | 1.75002656 |
| 29 | MP0001984_abnormal_olfaction | 1.70117444 |
| 30 | MP0010386_abnormal_urinary_bladder | 1.69933133 |
| 31 | MP0002733_abnormal_thermal_nociception | 1.69661133 |
| 32 | MP0001188_hyperpigmentation | 1.60618851 |
| 33 | MP0003633_abnormal_nervous_system | 1.57615112 |
| 34 | MP0003123_paternal_imprinting | 1.55035691 |
| 35 | MP0008569_lethality_at_weaning | 1.54985879 |
| 36 | MP0002557_abnormal_social/conspecific_i | 1.54222226 |
| 37 | MP0003690_abnormal_glial_cell | 1.54074260 |
| 38 | MP0006276_abnormal_autonomic_nervous | 1.49996215 |
| 39 | MP0001963_abnormal_hearing_physiology | 1.45875897 |
| 40 | MP0002736_abnormal_nociception_after | 1.44203276 |
| 41 | MP0006036_abnormal_mitochondrial_physio | 1.42362303 |
| 42 | MP0002876_abnormal_thyroid_physiology | 1.41098978 |
| 43 | MP0002909_abnormal_adrenal_gland | 1.38710948 |
| 44 | MP0002837_dystrophic_cardiac_calcinosis | 1.38642053 |
| 45 | MP0008872_abnormal_physiological_respon | 1.36237178 |
| 46 | MP0000955_abnormal_spinal_cord | 1.32623882 |
| 47 | MP0004147_increased_porphyrin_level | 1.31479007 |
| 48 | MP0002067_abnormal_sensory_capabilities | 1.28231271 |
| 49 | MP0001502_abnormal_circadian_rhythm | 1.20700026 |
| 50 | MP0002229_neurodegeneration | 1.20551898 |
| 51 | MP0003878_abnormal_ear_physiology | 1.15680295 |
| 52 | MP0005377_hearing/vestibular/ear_phenot | 1.15680295 |
| 53 | MP0006072_abnormal_retinal_apoptosis | 1.15544205 |
| 54 | MP0003283_abnormal_digestive_organ | 1.14325939 |
| 55 | MP0002066_abnormal_motor_capabilities/c | 1.13643021 |
| 56 | MP0004742_abnormal_vestibular_system | 1.11819005 |
| 57 | MP0002882_abnormal_neuron_morphology | 1.11416127 |
| 58 | MP0005645_abnormal_hypothalamus_physiol | 1.11171303 |
| 59 | MP0003631_nervous_system_phenotype | 1.11083453 |
| 60 | MP0002735_abnormal_chemical_nociception | 1.09539614 |
| 61 | MP0000026_abnormal_inner_ear | 1.08314379 |
| 62 | MP0003121_genomic_imprinting | 1.07844853 |
| 63 | MP0005670_abnormal_white_adipose | 1.05814271 |
| 64 | MP0005636_abnormal_mineral_homeostasis | 1.05367418 |
| 65 | MP0005332_abnormal_amino_acid | 1.01929171 |
| 66 | MP0001765_abnormal_ion_homeostasis | 1.01769531 |
| 67 | MP0003329_amyloid_beta_deposits | 0.98063398 |
| 68 | MP0004811_abnormal_neuron_physiology | 0.93730153 |
| 69 | MP0000013_abnormal_adipose_tissue | 0.92873147 |
| 70 | MP0005386_behavior/neurological_phenoty | 0.90841971 |
| 71 | MP0004924_abnormal_behavior | 0.90841971 |
| 72 | MP0004142_abnormal_muscle_tone | 0.90291200 |
| 73 | MP0005360_urolithiasis | 0.88577318 |
| 74 | MP0004145_abnormal_muscle_electrophysio | 0.87830245 |
| 75 | MP0001664_abnormal_digestion | 0.87671584 |
| 76 | MP0004019_abnormal_vitamin_homeostasis | 0.87350049 |
| 77 | MP0010329_abnormal_lipoprotein_level | 0.87121748 |
| 78 | MP0002184_abnormal_innervation | 0.86668131 |
| 79 | MP0003122_maternal_imprinting | 0.84530564 |
| 80 | MP0000778_abnormal_nervous_system | 0.84259621 |
| 81 | MP0002089_abnormal_postnatal_growth/wei | 0.84221109 |
| 82 | MP0005535_abnormal_body_temperature | 0.82180022 |
| 83 | MP0000230_abnormal_systemic_arterial | 0.81688311 |
| 84 | MP0005253_abnormal_eye_physiology | 0.80292384 |
| 85 | MP0003195_calcinosis | 0.79977251 |
| 86 | MP0002752_abnormal_somatic_nervous | 0.78896704 |
| 87 | MP0000920_abnormal_myelination | 0.78381156 |
| 88 | MP0001756_abnormal_urination | 0.78364296 |
| 89 | MP0001986_abnormal_taste_sensitivity | 0.74174149 |
| 90 | MP0000631_abnormal_neuroendocrine_gland | 0.72105864 |
| 91 | MP0004215_abnormal_myocardial_fiber | 0.70687644 |
| 92 | MP0003866_abnormal_defecation | 0.69883682 |
| 93 | MP0003011_delayed_dark_adaptation | 0.69256796 |
| 94 | MP0005166_decreased_susceptibility_to | 0.68346080 |
| 95 | MP0002693_abnormal_pancreas_physiology | 0.68096125 |
| 96 | MP0003632_abnormal_nervous_system | 0.67994020 |
| 97 | MP0004085_abnormal_heartbeat | 0.66793806 |
| 98 | MP0002069_abnormal_eating/drinking_beha | 0.64958323 |
| 99 | MP0002163_abnormal_gland_morphology | 0.63124784 |
| 100 | MP0003075_altered_response_to | 0.62027340 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nonprogressive disorder (HP:0003680) | 5.62749867 |
| 2 | Increased circulating renin level (HP:0000848) | 4.90838746 |
| 3 | Focal motor seizures (HP:0011153) | 4.62010820 |
| 4 | Focal seizures (HP:0007359) | 4.53474545 |
| 5 | Abnormality of binocular vision (HP:0011514) | 4.41925660 |
| 6 | Diplopia (HP:0000651) | 4.41925660 |
| 7 | Myokymia (HP:0002411) | 4.21390486 |
| 8 | Metabolic alkalosis (HP:0200114) | 3.99042391 |
| 9 | Acute necrotizing encephalopathy (HP:0006965) | 3.89650631 |
| 10 | Abnormal eating behavior (HP:0100738) | 3.86846592 |
| 11 | Action tremor (HP:0002345) | 3.74047921 |
| 12 | Epileptic encephalopathy (HP:0200134) | 3.60868496 |
| 13 | Progressive macrocephaly (HP:0004481) | 3.38403291 |
| 14 | Febrile seizures (HP:0002373) | 3.32431667 |
| 15 | Hypomagnesemia (HP:0002917) | 3.30317830 |
| 16 | Absence seizures (HP:0002121) | 3.29564753 |
| 17 | Dialeptic seizures (HP:0011146) | 3.29374597 |
| 18 | Abnormality of magnesium homeostasis (HP:0004921) | 3.27059580 |
| 19 | Hemiparesis (HP:0001269) | 3.26935762 |
| 20 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.25844591 |
| 21 | Atonic seizures (HP:0010819) | 3.22711945 |
| 22 | Peripheral hypomyelination (HP:0007182) | 3.09579242 |
| 23 | Acute encephalopathy (HP:0006846) | 3.09082756 |
| 24 | Abnormal drinking behavior (HP:0030082) | 2.96273490 |
| 25 | Polydipsia (HP:0001959) | 2.96273490 |
| 26 | Ankle clonus (HP:0011448) | 2.89818396 |
| 27 | Progressive cerebellar ataxia (HP:0002073) | 2.89411858 |
| 28 | Papilledema (HP:0001085) | 2.88365955 |
| 29 | Hypokalemic alkalosis (HP:0001949) | 2.87843453 |
| 30 | Generalized tonic-clonic seizures (HP:0002069) | 2.83904071 |
| 31 | Limb dystonia (HP:0002451) | 2.83262957 |
| 32 | Abnormality of renin-angiotensin system (HP:0000847) | 2.74753032 |
| 33 | Polyphagia (HP:0002591) | 2.72871271 |
| 34 | Epileptiform EEG discharges (HP:0011182) | 2.72333046 |
| 35 | Mitochondrial inheritance (HP:0001427) | 2.64916839 |
| 36 | Intention tremor (HP:0002080) | 2.54251411 |
| 37 | Status epilepticus (HP:0002133) | 2.52911379 |
| 38 | Ventricular fibrillation (HP:0001663) | 2.46183500 |
| 39 | Confusion (HP:0001289) | 2.44631499 |
| 40 | Anxiety (HP:0000739) | 2.40236674 |
| 41 | Metaphyseal dysplasia (HP:0100255) | 2.40013583 |
| 42 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.37262462 |
| 43 | Cerebral edema (HP:0002181) | 2.33699979 |
| 44 | Hyperaldosteronism (HP:0000859) | 2.27271072 |
| 45 | Broad-based gait (HP:0002136) | 2.22005823 |
| 46 | Abnormality of cochlea (HP:0000375) | 2.20435652 |
| 47 | Increased CSF lactate (HP:0002490) | 2.18954178 |
| 48 | Syncope (HP:0001279) | 2.16750837 |
| 49 | Hyperventilation (HP:0002883) | 2.16307932 |
| 50 | Hyperthyroidism (HP:0000836) | 2.15743240 |
| 51 | Abnormality of midbrain morphology (HP:0002418) | 2.14356471 |
| 52 | Molar tooth sign on MRI (HP:0002419) | 2.14356471 |
| 53 | Dysdiadochokinesis (HP:0002075) | 2.13969757 |
| 54 | Visual hallucinations (HP:0002367) | 2.09865099 |
| 55 | Pigmentary retinal degeneration (HP:0001146) | 2.09841276 |
| 56 | Sleep apnea (HP:0010535) | 2.06626474 |
| 57 | EEG with generalized epileptiform discharges (HP:0011198) | 2.06278315 |
| 58 | Gaze-evoked nystagmus (HP:0000640) | 2.04184337 |
| 59 | Obstructive sleep apnea (HP:0002870) | 2.04008449 |
| 60 | Leukodystrophy (HP:0002415) | 2.03258018 |
| 61 | Alkalosis (HP:0001948) | 2.02741161 |
| 62 | Morphological abnormality of the inner ear (HP:0011390) | 2.02510044 |
| 63 | Renal salt wasting (HP:0000127) | 2.00512226 |
| 64 | Delayed CNS myelination (HP:0002188) | 1.98597700 |
| 65 | Congenital stationary night blindness (HP:0007642) | 1.97719500 |
| 66 | Bundle branch block (HP:0011710) | 1.96579441 |
| 67 | Polyuria (HP:0000103) | 1.94998818 |
| 68 | Abnormality of renal excretion (HP:0011036) | 1.92825542 |
| 69 | Hyperphosphatemia (HP:0002905) | 1.92779932 |
| 70 | Megalencephaly (HP:0001355) | 1.91822497 |
| 71 | Pancreatic fibrosis (HP:0100732) | 1.91524145 |
| 72 | Hyperparathyroidism (HP:0000843) | 1.89227856 |
| 73 | Nephronophthisis (HP:0000090) | 1.85543834 |
| 74 | Abnormal urine output (HP:0012590) | 1.83956826 |
| 75 | Hepatic necrosis (HP:0002605) | 1.82552528 |
| 76 | Neurofibrillary tangles (HP:0002185) | 1.81773257 |
| 77 | Agitation (HP:0000713) | 1.81078647 |
| 78 | 3-Methylglutaconic aciduria (HP:0003535) | 1.80542568 |
| 79 | Congenital, generalized hypertrichosis (HP:0004540) | 1.80132987 |
| 80 | Medial flaring of the eyebrow (HP:0010747) | 1.79808969 |
| 81 | Focal dystonia (HP:0004373) | 1.78376832 |
| 82 | Hyperphosphaturia (HP:0003109) | 1.78248866 |
| 83 | Hypsarrhythmia (HP:0002521) | 1.77336773 |
| 84 | Hypoplastic left heart (HP:0004383) | 1.76990293 |
| 85 | Torticollis (HP:0000473) | 1.76750442 |
| 86 | Glycosuria (HP:0003076) | 1.76529190 |
| 87 | Abnormality of urine glucose concentration (HP:0011016) | 1.76529190 |
| 88 | Supranuclear gaze palsy (HP:0000605) | 1.75753243 |
| 89 | Optic disc pallor (HP:0000543) | 1.75160865 |
| 90 | Ulnar claw (HP:0001178) | 1.74735494 |
| 91 | Postural tremor (HP:0002174) | 1.74590145 |
| 92 | Clumsiness (HP:0002312) | 1.74553715 |
| 93 | Truncal ataxia (HP:0002078) | 1.73872138 |
| 94 | Hemiplegia (HP:0002301) | 1.73715048 |
| 95 | Prolonged QT interval (HP:0001657) | 1.72895218 |
| 96 | Delusions (HP:0000746) | 1.71544879 |
| 97 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 1.70042472 |
| 98 | Abnormality of renal resorption (HP:0011038) | 1.69499807 |
| 99 | Genetic anticipation (HP:0003743) | 1.68539905 |
| 100 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.66660853 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NTRK3 | 3.30616422 |
| 2 | DMPK | 3.27022838 |
| 3 | PINK1 | 3.23277539 |
| 4 | RIPK4 | 2.79796970 |
| 5 | MARK1 | 2.65423469 |
| 6 | PAK3 | 2.65287045 |
| 7 | PAK6 | 2.52304815 |
| 8 | BMPR2 | 2.43712885 |
| 9 | FRK | 2.42218055 |
| 10 | UHMK1 | 2.04483403 |
| 11 | MINK1 | 2.03462166 |
| 12 | PHKG2 | 1.87614142 |
| 13 | PHKG1 | 1.87614142 |
| 14 | PLK2 | 1.86748523 |
| 15 | GRK5 | 1.83601998 |
| 16 | PRKD3 | 1.80539875 |
| 17 | DAPK2 | 1.76355292 |
| 18 | NTRK2 | 1.72036825 |
| 19 | TAOK3 | 1.69859752 |
| 20 | TLK1 | 1.66037472 |
| 21 | CAMKK1 | 1.61190823 |
| 22 | MAP3K12 | 1.47153825 |
| 23 | LIMK1 | 1.45786969 |
| 24 | GRK1 | 1.41496278 |
| 25 | PRKCG | 1.41016471 |
| 26 | MAPK13 | 1.40153897 |
| 27 | CAMK2A | 1.37745963 |
| 28 | CASK | 1.33937077 |
| 29 | TNK2 | 1.30448700 |
| 30 | ADRBK2 | 1.24417539 |
| 31 | SGK1 | 1.21253247 |
| 32 | CAMK1 | 1.21110230 |
| 33 | MAPKAPK3 | 1.19496527 |
| 34 | BMPR1B | 1.19123337 |
| 35 | SGK223 | 1.17306005 |
| 36 | SGK494 | 1.17306005 |
| 37 | CDK5 | 1.15942166 |
| 38 | ACVR1B | 1.15826620 |
| 39 | WNK4 | 1.13711274 |
| 40 | TNIK | 1.10684254 |
| 41 | CAMK2B | 1.07480181 |
| 42 | SGK2 | 1.06807096 |
| 43 | MAP3K4 | 1.02984137 |
| 44 | CAMK2G | 1.02821299 |
| 45 | ABL2 | 1.02425664 |
| 46 | STK39 | 0.97053070 |
| 47 | EPHA4 | 0.96515391 |
| 48 | WNK1 | 0.95088166 |
| 49 | CDK14 | 0.92685363 |
| 50 | CDK11A | 0.92599342 |
| 51 | PKN1 | 0.92338989 |
| 52 | CSNK1E | 0.91664543 |
| 53 | NUAK1 | 0.90700004 |
| 54 | MAP2K4 | 0.89490721 |
| 55 | CDK19 | 0.86486300 |
| 56 | PRKG1 | 0.86368305 |
| 57 | INSRR | 0.86046181 |
| 58 | MAP2K6 | 0.84778526 |
| 59 | PTK2B | 0.83861182 |
| 60 | CDK15 | 0.83850635 |
| 61 | MAPK12 | 0.83612130 |
| 62 | CAMK2D | 0.81346308 |
| 63 | NTRK1 | 0.80913591 |
| 64 | MAP2K7 | 0.77333184 |
| 65 | RPS6KA3 | 0.76969863 |
| 66 | PRKCQ | 0.76127717 |
| 67 | TEC | 0.75970141 |
| 68 | CDK18 | 0.74994602 |
| 69 | TESK1 | 0.70998926 |
| 70 | MYLK | 0.69481841 |
| 71 | OXSR1 | 0.69114121 |
| 72 | PRKCA | 0.69059352 |
| 73 | STK38 | 0.68270867 |
| 74 | STK16 | 0.67134940 |
| 75 | PRKACA | 0.65595791 |
| 76 | PRKCZ | 0.65064975 |
| 77 | ADRBK1 | 0.64687953 |
| 78 | PIK3CA | 0.64227494 |
| 79 | STK11 | 0.62423694 |
| 80 | TYRO3 | 0.61050206 |
| 81 | CSNK1A1 | 0.55829044 |
| 82 | PRKCH | 0.53885727 |
| 83 | SIK2 | 0.53832521 |
| 84 | MAPK4 | 0.53605332 |
| 85 | MAPK10 | 0.53017594 |
| 86 | PRKCE | 0.52783483 |
| 87 | MAP3K2 | 0.49415993 |
| 88 | FES | 0.49315020 |
| 89 | SGK3 | 0.49145276 |
| 90 | MST4 | 0.48402106 |
| 91 | PRKD1 | 0.47517143 |
| 92 | CDC7 | 0.44661495 |
| 93 | PRKCI | 0.44115442 |
| 94 | PRKG2 | 0.43835428 |
| 95 | MARK2 | 0.42989517 |
| 96 | PRKACG | 0.41521650 |
| 97 | PRKACB | 0.41309270 |
| 98 | HIPK2 | 0.41088984 |
| 99 | SYK | 0.40571211 |
| 100 | ROCK1 | 0.38679594 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.50297315 |
| 2 | Insulin secretion_Homo sapiens_hsa04911 | 3.26993931 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.77934687 |
| 4 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.75587044 |
| 5 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.37998301 |
| 6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.35439375 |
| 7 | Morphine addiction_Homo sapiens_hsa05032 | 2.18606395 |
| 8 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.15731175 |
| 9 | GABAergic synapse_Homo sapiens_hsa04727 | 2.15421697 |
| 10 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.14411202 |
| 11 | Gastric acid secretion_Homo sapiens_hsa04971 | 2.11033155 |
| 12 | Mineral absorption_Homo sapiens_hsa04978 | 2.09643545 |
| 13 | Long-term potentiation_Homo sapiens_hsa04720 | 2.07033458 |
| 14 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.02629711 |
| 15 | Salivary secretion_Homo sapiens_hsa04970 | 2.01457124 |
| 16 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.91496442 |
| 17 | Parkinsons disease_Homo sapiens_hsa05012 | 1.88047346 |
| 18 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.85038730 |
| 19 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.82755651 |
| 20 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.80602485 |
| 21 | Alzheimers disease_Homo sapiens_hsa05010 | 1.77893148 |
| 22 | Renin secretion_Homo sapiens_hsa04924 | 1.62458886 |
| 23 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.57860661 |
| 24 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.50040999 |
| 25 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.47544637 |
| 26 | Phototransduction_Homo sapiens_hsa04744 | 1.45196897 |
| 27 | Cocaine addiction_Homo sapiens_hsa05030 | 1.43809558 |
| 28 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.43121982 |
| 29 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.40515148 |
| 30 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.40227472 |
| 31 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.34729587 |
| 32 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.34696126 |
| 33 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.32011176 |
| 34 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.31511549 |
| 35 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.27884643 |
| 36 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.26088367 |
| 37 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.24260221 |
| 38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.24122991 |
| 39 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.23736487 |
| 40 | Histidine metabolism_Homo sapiens_hsa00340 | 1.21651065 |
| 41 | Olfactory transduction_Homo sapiens_hsa04740 | 1.19145991 |
| 42 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.18652179 |
| 43 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.13313127 |
| 44 | Taste transduction_Homo sapiens_hsa04742 | 1.11751157 |
| 45 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.10618522 |
| 46 | Long-term depression_Homo sapiens_hsa04730 | 1.06779914 |
| 47 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.04972267 |
| 48 | Huntingtons disease_Homo sapiens_hsa05016 | 1.00952122 |
| 49 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.00767235 |
| 50 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.99484985 |
| 51 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.98584631 |
| 52 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.93745351 |
| 53 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.89963367 |
| 54 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.89943806 |
| 55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.89324018 |
| 56 | Bile secretion_Homo sapiens_hsa04976 | 0.86458243 |
| 57 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.84603381 |
| 58 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.84258382 |
| 59 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.83009302 |
| 60 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.78833696 |
| 61 | Asthma_Homo sapiens_hsa05310 | 0.76672984 |
| 62 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.75147619 |
| 63 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.72883908 |
| 64 | Sulfur relay system_Homo sapiens_hsa04122 | 0.68784932 |
| 65 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.68322971 |
| 66 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.68130496 |
| 67 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.67844895 |
| 68 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.63803860 |
| 69 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.57022923 |
| 70 | Protein export_Homo sapiens_hsa03060 | 0.55366488 |
| 71 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.54868522 |
| 72 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.51103816 |
| 73 | Melanogenesis_Homo sapiens_hsa04916 | 0.51059800 |
| 74 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.48097686 |
| 75 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.46852926 |
| 76 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.46129209 |
| 77 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.45786050 |
| 78 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.44693914 |
| 79 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.43620901 |
| 80 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.43047603 |
| 81 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.42768808 |
| 82 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.41771260 |
| 83 | Ribosome_Homo sapiens_hsa03010 | 0.39134836 |
| 84 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.38134467 |
| 85 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.37822446 |
| 86 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.35960069 |
| 87 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.35427378 |
| 88 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.34477729 |
| 89 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.34301469 |
| 90 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.34160276 |
| 91 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.33421872 |
| 92 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.32230854 |
| 93 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.32112445 |
| 94 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.31653535 |
| 95 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.31409061 |
| 96 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.30654270 |
| 97 | Gap junction_Homo sapiens_hsa04540 | 0.30527402 |
| 98 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.30249565 |
| 99 | Retinol metabolism_Homo sapiens_hsa00830 | 0.29884798 |
| 100 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.29625050 |

