MTUS2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cardiac myofibril assembly (GO:0055003)6.11961078
2regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO5.91423225
3negative regulation of potassium ion transmembrane transporter activity (GO:1901017)5.57059897
4regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)5.54857840
5sarcomere organization (GO:0045214)5.54420968
6cell communication by electrical coupling involved in cardiac conduction (GO:0086064)5.42822277
7negative regulation of potassium ion transmembrane transport (GO:1901380)5.41629638
8regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)5.32111070
9positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)5.24380691
10cardiac muscle contraction (GO:0060048)5.07352052
11myofibril assembly (GO:0030239)5.02239060
12cell communication by electrical coupling (GO:0010644)4.90930837
13cell communication involved in cardiac conduction (GO:0086065)4.72607862
14regulation of membrane repolarization (GO:0060306)4.71351035
15regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.64925182
16ventricular cardiac muscle cell action potential (GO:0086005)4.60333235
17membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.52589734
18negative regulation of cytosolic calcium ion concentration (GO:0051481)4.49999335
19regulation of actin filament-based movement (GO:1903115)4.36424930
20regulation of cell communication by electrical coupling (GO:0010649)4.34494458
21regulation of sarcomere organization (GO:0060297)4.34338154
22cardiac muscle cell development (GO:0055013)4.31848087
23regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.28679092
24cardiac muscle hypertrophy (GO:0003300)4.23969004
25regulation of relaxation of muscle (GO:1901077)4.19081476
26positive regulation of potassium ion transmembrane transporter activity (GO:1901018)4.15182680
27tricarboxylic acid cycle (GO:0006099)4.14985110
28positive regulation of potassium ion transmembrane transport (GO:1901381)4.08563840
29cardiac cell development (GO:0055006)4.00403539
30striated muscle hypertrophy (GO:0014897)4.00255798
31adult heart development (GO:0007512)3.88014883
32ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.80264294
33vocalization behavior (GO:0071625)3.76589476
34regulation of the force of heart contraction (GO:0002026)3.76431055
35cardiac muscle tissue morphogenesis (GO:0055008)3.76143039
36cardiac conduction (GO:0061337)3.74483888
37plasma membrane repair (GO:0001778)3.73010452
38regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.71120524
39striated muscle contraction (GO:0006941)3.70536737
40cardiac muscle cell action potential (GO:0086001)3.70187260
41sarcoplasmic reticulum calcium ion transport (GO:0070296)3.68844481
42regulation of striated muscle contraction (GO:0006942)3.68062068
43actomyosin structure organization (GO:0031032)3.67584165
44cardiac muscle cell action potential involved in contraction (GO:0086002)3.67496668
45regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.66707128
46detection of calcium ion (GO:0005513)3.65165878
47regulation of heart rate by cardiac conduction (GO:0086091)3.65140246
48regulation of short-term neuronal synaptic plasticity (GO:0048172)3.61773496
49dendritic spine morphogenesis (GO:0060997)3.61426503
50relaxation of cardiac muscle (GO:0055119)3.59845906
51regulation of acyl-CoA biosynthetic process (GO:0050812)3.56239769
52positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.55790204
53regulation of cardiac muscle contraction (GO:0055117)3.53788644
54muscle filament sliding (GO:0030049)3.53542839
55actin-myosin filament sliding (GO:0033275)3.53542839
56positive regulation of synapse maturation (GO:0090129)3.51960731
57cardiac chamber formation (GO:0003207)3.49176341
58regulation of cardiac muscle cell contraction (GO:0086004)3.48582997
59regulation of synapse structural plasticity (GO:0051823)3.47896009
60positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.46273926
61potassium ion export (GO:0071435)3.45785761
62positive regulation of action potential (GO:0045760)3.44484167
63muscle hypertrophy (GO:0014896)3.43452721
64regulation of heart rate (GO:0002027)3.42815357
65positive regulation of heart rate (GO:0010460)3.41359826
66regulation of calcium ion transmembrane transport (GO:1903169)3.41339218
67regulation of calcium ion transmembrane transporter activity (GO:1901019)3.41339218
68negative regulation of potassium ion transport (GO:0043267)3.39600533
69negative regulation of cardiac muscle cell apoptotic process (GO:0010667)3.36571118
70G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.35269604
71synaptic vesicle exocytosis (GO:0016079)3.35133332
72regulation of cofactor metabolic process (GO:0051193)3.33627262
73regulation of coenzyme metabolic process (GO:0051196)3.33627262
74positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.33045729
75membrane repolarization during cardiac muscle cell action potential (GO:0086013)3.31544145
76regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.31071564
77muscle tissue morphogenesis (GO:0060415)3.29539323
78synaptic vesicle maturation (GO:0016188)3.29220313
79heart trabecula formation (GO:0060347)3.27748104
80negative regulation of protein localization to cell surface (GO:2000009)3.22570309
81positive regulation of potassium ion transport (GO:0043268)3.21347315
82membrane depolarization during action potential (GO:0086010)3.20220870
83sodium ion export (GO:0071436)3.20068730
84regulation of potassium ion transmembrane transport (GO:1901379)3.19971003
85cardiac muscle hypertrophy in response to stress (GO:0014898)3.19955981
86muscle hypertrophy in response to stress (GO:0003299)3.19955981
87cardiac muscle adaptation (GO:0014887)3.19955981
88cardiac ventricle formation (GO:0003211)3.18688525
89cellular potassium ion homeostasis (GO:0030007)3.18153052
90regulation of ATP catabolic process (GO:1903289)3.17339949
91regulation of ATPase activity (GO:0043462)3.17339949
92regulation of heart contraction (GO:0008016)3.17300507
93heart process (GO:0003015)3.16335732
94heart contraction (GO:0060047)3.16335732
95bundle of His cell to Purkinje myocyte communication (GO:0086069)3.16271978
96activation of protein kinase A activity (GO:0034199)3.15345099
97regulation of potassium ion transmembrane transporter activity (GO:1901016)3.15037051
98positive regulation of ATPase activity (GO:0032781)3.14203883
99positive regulation of ATP catabolic process (GO:1903291)3.14203883
100striatum development (GO:0021756)3.10580629
101membrane repolarization (GO:0086009)3.09889112
102neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.08817353
103protein localization to synapse (GO:0035418)3.08577123
104adrenergic receptor signaling pathway (GO:0071875)3.08056776
105chemosensory behavior (GO:0007635)3.07722483
106regulation of glutamate receptor signaling pathway (GO:1900449)3.06227870
107positive regulation of cation channel activity (GO:2001259)3.05504154
108regulation of voltage-gated calcium channel activity (GO:1901385)3.03086550
109neuronal ion channel clustering (GO:0045161)3.02066000
110membrane repolarization during action potential (GO:0086011)3.01256450
111actin-mediated cell contraction (GO:0070252)3.00456072
112regulation of action potential (GO:0098900)2.99756906
113urinary tract smooth muscle contraction (GO:0014848)2.99414551
114positive regulation of sodium ion transport (GO:0010765)2.97652264
115multicellular organismal signaling (GO:0035637)2.97584177
116synaptic vesicle docking involved in exocytosis (GO:0016081)2.97348236
117regulation of synapse maturation (GO:0090128)2.95786800
118positive regulation of ion transmembrane transporter activity (GO:0032414)2.94396276
119negative regulation of heart rate (GO:0010459)2.92405135
120regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.86955554
121action potential (GO:0001508)2.81155391
122regulation of cardioblast differentiation (GO:0051890)2.78468622
123insulin secretion (GO:0030073)2.76263998
124neuronal action potential (GO:0019228)2.72964889
125positive regulation of heart contraction (GO:0045823)2.71865470
126negative regulation of hormone biosynthetic process (GO:0032353)2.67030791
127cAMP biosynthetic process (GO:0006171)2.64079836
128positive regulation of membrane potential (GO:0045838)2.62927725
129regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.57636500
130desmosome organization (GO:0002934)2.57585689
131presynaptic membrane organization (GO:0097090)2.57564198
132positive regulation of cardiac muscle cell differentiation (GO:2000727)2.57544552
133adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.56372373
134glutamate secretion (GO:0014047)2.55924317
135regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.55266010
136regulation of postsynaptic membrane potential (GO:0060078)2.55058557
137righting reflex (GO:0060013)2.53655371

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.17185714
2GBX2_23144817_ChIP-Seq_PC3_Human3.15621497
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.71730245
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.64697980
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.63769462
6EP300_21415370_ChIP-Seq_HL-1_Mouse2.44287575
7ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.42715397
8DROSHA_22980978_ChIP-Seq_HELA_Human2.42583517
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.41511001
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.41511001
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.34434941
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.33248921
13* REST_21632747_ChIP-Seq_MESCs_Mouse2.21453062
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.19060001
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.16625924
16* EZH2_27294783_Chip-Seq_ESCs_Mouse2.11907416
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.09449059
18* RARB_27405468_Chip-Seq_BRAIN_Mouse2.07594188
19SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.05053327
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.03255847
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.98521846
22RNF2_27304074_Chip-Seq_ESCs_Mouse1.96348857
23SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.96077246
24REST_18959480_ChIP-ChIP_MESCs_Mouse1.89853433
25IGF1R_20145208_ChIP-Seq_DFB_Human1.89102076
26SUZ12_27294783_Chip-Seq_ESCs_Mouse1.88373530
27EED_16625203_ChIP-ChIP_MESCs_Mouse1.85960612
28AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.75960089
29CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.66525525
30EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.64355225
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.64080899
32* SMAD4_21799915_ChIP-Seq_A2780_Human1.62711197
33AR_21572438_ChIP-Seq_LNCaP_Human1.60965620
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.60570424
35MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.59210450
36CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.57666269
37* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.56525728
38BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.52818112
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.51663665
40NR3C1_23031785_ChIP-Seq_PC12_Mouse1.48922953
41ZNF274_21170338_ChIP-Seq_K562_Hela1.48785527
42TAF15_26573619_Chip-Seq_HEK293_Human1.47975995
43CDX2_19796622_ChIP-Seq_MESCs_Mouse1.47290722
44RNF2_27304074_Chip-Seq_NSC_Mouse1.44599952
45RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.41854202
46SOX2_21211035_ChIP-Seq_LN229_Gbm1.40270919
47CTBP1_25329375_ChIP-Seq_LNCAP_Human1.38354149
48RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.38350636
49ESR1_20079471_ChIP-ChIP_T-47D_Human1.37593422
50FUS_26573619_Chip-Seq_HEK293_Human1.35592945
51ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.35559004
52GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.34560629
53PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.34104826
54HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.33815469
55OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33610434
56TBX20_22328084_ChIP-Seq_HEART_Mouse1.32040436
57TBX20_22080862_ChIP-Seq_HEART_Mouse1.32040436
58MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.26866589
59PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.26458762
60VDR_22108803_ChIP-Seq_LS180_Human1.25589789
61AR_19668381_ChIP-Seq_PC3_Human1.25340021
62ZFP57_27257070_Chip-Seq_ESCs_Mouse1.25014269
63RING1B_27294783_Chip-Seq_ESCs_Mouse1.24946154
64SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.23250352
65TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.22003907
66SMAD3_21741376_ChIP-Seq_EPCs_Human1.20907735
67SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.19784110
68EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.19721288
69CBX2_27304074_Chip-Seq_ESCs_Mouse1.18385821
70* NANOG_18555785_Chip-Seq_ESCs_Mouse1.18324899
71MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.16475844
72TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.15909677
73STAT3_23295773_ChIP-Seq_U87_Human1.15272466
74* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14538021
75MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.13601848
76P300_19829295_ChIP-Seq_ESCs_Human1.11920621
77* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.11865528
78HTT_18923047_ChIP-ChIP_STHdh_Human1.11279416
79POU3F2_20337985_ChIP-ChIP_501MEL_Human1.11220653
80TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10987370
81SMAD4_21741376_ChIP-Seq_EPCs_Human1.10721133
82* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.10457759
83TCF4_23295773_ChIP-Seq_U87_Human1.09265510
84SMAD3_21741376_ChIP-Seq_HESCs_Human1.09088609
85P53_22127205_ChIP-Seq_FIBROBLAST_Human1.08695262
86* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08610376
87CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08149142
88SMAD4_21741376_ChIP-Seq_HESCs_Human1.07956768
89PIAS1_25552417_ChIP-Seq_VCAP_Human1.07423819
90TOP2B_26459242_ChIP-Seq_MCF-7_Human1.07153949
91TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06386581
92BMI1_23680149_ChIP-Seq_NPCS_Mouse1.06155378
93AR_25329375_ChIP-Seq_VCAP_Human1.05446109
94FLI1_27457419_Chip-Seq_LIVER_Mouse1.04775256
95ER_23166858_ChIP-Seq_MCF-7_Human1.04680016
96CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.04572923
97YAP1_20516196_ChIP-Seq_MESCs_Mouse1.04539949
98* RUNX2_22187159_ChIP-Seq_PCA_Human1.02461935
99TAL1_26923725_Chip-Seq_HPCs_Mouse1.02452804
100CTCF_27219007_Chip-Seq_Bcells_Human1.01410423
101* TBL1_22424771_ChIP-Seq_293T_Human1.01199372
102UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.01059105
103IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.00410957
104CBP_20019798_ChIP-Seq_JUKART_Human1.00410957
105EWS_26573619_Chip-Seq_HEK293_Human0.99433013
106EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.99116998
107TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.98690910
108P53_22387025_ChIP-Seq_ESCs_Mouse0.98663384
109EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.98218511
110STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.98196320
111NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97954361
112IKZF1_21737484_ChIP-ChIP_HCT116_Human0.97886359
113AHR_22903824_ChIP-Seq_MCF-7_Human0.95674756
114KDM2B_26808549_Chip-Seq_K562_Human0.95565883
115ARNT_22903824_ChIP-Seq_MCF-7_Human0.95361632
116RING1B_27294783_Chip-Seq_NPCs_Mouse0.94962618
117SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.94793435
118ISL1_27105846_Chip-Seq_CPCs_Mouse0.94361547
119BCAT_22108803_ChIP-Seq_LS180_Human0.93887304
120RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.91044250
121SMAD_19615063_ChIP-ChIP_OVARY_Human0.90682800
122EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.89969439
123TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.89606906
124DNAJC2_21179169_ChIP-ChIP_NT2_Human0.89340931
125TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89139690
126POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.89139690
127ZFP281_18757296_ChIP-ChIP_E14_Mouse0.88945321
128ZNF217_24962896_ChIP-Seq_MCF-7_Human0.88450998

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis5.30858619
2MP0004084_abnormal_cardiac_muscle4.52755423
3MP0003646_muscle_fatigue4.21425954
4MP0004215_abnormal_myocardial_fiber4.17824331
5MP0000751_myopathy3.96541990
6MP0004036_abnormal_muscle_relaxation3.37017694
7MP0004859_abnormal_synaptic_plasticity3.22300817
8MP0003137_abnormal_impulse_conducting2.76944184
9MP0003880_abnormal_central_pattern2.73119150
10MP0005330_cardiomyopathy2.71169804
11MP0002972_abnormal_cardiac_muscle2.51022881
12MP0008775_abnormal_heart_ventricle2.48274990
13MP0000749_muscle_degeneration2.47946694
14MP0003283_abnormal_digestive_organ2.34417100
15MP0003635_abnormal_synaptic_transmissio2.28442488
16MP0004085_abnormal_heartbeat2.23198616
17MP0004145_abnormal_muscle_electrophysio2.20595292
18MP0004484_altered_response_of2.20036669
19MP0005620_abnormal_muscle_contractility2.19054836
20MP0004087_abnormal_muscle_fiber2.04164118
21MP0009046_muscle_twitch1.99701917
22MP0003195_calcinosis1.99172369
23MP0004270_analgesia1.92585847
24MP0005385_cardiovascular_system_phenoty1.89512536
25MP0001544_abnormal_cardiovascular_syste1.89512536
26MP0009745_abnormal_behavioral_response1.80578394
27MP0006138_congestive_heart_failure1.80201798
28MP0002063_abnormal_learning/memory/cond1.79757329
29MP0004233_abnormal_muscle_weight1.77704524
30MP0002106_abnormal_muscle_physiology1.74085682
31MP0002822_catalepsy1.72472465
32MP0002064_seizures1.68642202
33MP0010630_abnormal_cardiac_muscle1.63889278
34MP0008877_abnormal_DNA_methylation1.63437756
35MP0002272_abnormal_nervous_system1.61765417
36MP0004510_myositis1.60093600
37MP0002734_abnormal_mechanical_nocicepti1.55896314
38MP0001968_abnormal_touch/_nociception1.55391978
39MP0002127_abnormal_cardiovascular_syste1.53185867
40MP0000750_abnormal_muscle_regeneration1.51616479
41MP0002269_muscular_atrophy1.49350892
42MP0002572_abnormal_emotion/affect_behav1.49079607
43MP0004130_abnormal_muscle_cell1.47198964
44MP0003121_genomic_imprinting1.47126509
45MP0001486_abnormal_startle_reflex1.43304205
46MP0005423_abnormal_somatic_nervous1.42417816
47MP0000569_abnormal_digit_pigmentation1.40835826
48MP0005369_muscle_phenotype1.40102502
49MP0002735_abnormal_chemical_nociception1.38364391
50MP0005386_behavior/neurological_phenoty1.37289684
51MP0004924_abnormal_behavior1.37289684
52MP0005551_abnormal_eye_electrophysiolog1.33830999
53MP0006276_abnormal_autonomic_nervous1.33332956
54MP0002067_abnormal_sensory_capabilities1.32038523
55MP0003221_abnormal_cardiomyocyte_apopto1.31809747
56MP0002909_abnormal_adrenal_gland1.30274567
57MP0001440_abnormal_grooming_behavior1.29878552
58MP0000759_abnormal_skeletal_muscle1.29377482
59MP0006072_abnormal_retinal_apoptosis1.28272007
60MP0002234_abnormal_pharynx_morphology1.27069019
61MP0001984_abnormal_olfaction1.26874340
62MP0003123_paternal_imprinting1.26562412
63MP0008569_lethality_at_weaning1.25128656
64MP0002184_abnormal_innervation1.25071190
65MP0000747_muscle_weakness1.23510633
66MP0001944_abnormal_pancreas_morphology1.22361452
67MP0001970_abnormal_pain_threshold1.12689788
68MP0002736_abnormal_nociception_after1.10783137
69MP0001529_abnormal_vocalization1.10176320
70MP0002332_abnormal_exercise_endurance1.09716815
71MP0003950_abnormal_plasma_membrane1.09588000
72MP0003828_pulmonary_edema1.09573366
73MP0002693_abnormal_pancreas_physiology1.08095464
74MP0002638_abnormal_pupillary_reflex1.06774326
75MP0005084_abnormal_gallbladder_morpholo1.05410430
76MP0000778_abnormal_nervous_system1.04737073
77MP0002102_abnormal_ear_morphology1.04319791
78MP0001986_abnormal_taste_sensitivity1.02058021
79MP0001502_abnormal_circadian_rhythm1.01548628
80MP0010234_abnormal_vibrissa_follicle0.98597425
81MP0002733_abnormal_thermal_nociception0.98517688
82MP0003879_abnormal_hair_cell0.98035975
83MP0010386_abnormal_urinary_bladder0.95424100
84MP0005645_abnormal_hypothalamus_physiol0.95184037
85MP0001501_abnormal_sleep_pattern0.93938150
86MP0006036_abnormal_mitochondrial_physio0.92203923
87MP0003122_maternal_imprinting0.91198296
88MP0002557_abnormal_social/conspecific_i0.90982749
89MP0006035_abnormal_mitochondrial_morpho0.89779111
90MP0008961_abnormal_basal_metabolism0.89322740
91MP0005379_endocrine/exocrine_gland_phen0.87368388
92MP0002882_abnormal_neuron_morphology0.87249671
93MP0004811_abnormal_neuron_physiology0.86995815
94MP0004147_increased_porphyrin_level0.86705082
95MP0002078_abnormal_glucose_homeostasis0.85203334
96MP0004858_abnormal_nervous_system0.84961467
97MP0002928_abnormal_bile_duct0.84831955
98MP0002066_abnormal_motor_capabilities/c0.84261151
99MP0003119_abnormal_digestive_system0.83789676
100MP0004133_heterotaxia0.83699378
101MP0003890_abnormal_embryonic-extraembry0.82091790
102MP0004885_abnormal_endolymph0.81619840
103MP0002090_abnormal_vision0.80231646
104MP0003787_abnormal_imprinting0.77470349
105MP0001485_abnormal_pinna_reflex0.76887103
106MP0003329_amyloid_beta_deposits0.75976308
107MP0005646_abnormal_pituitary_gland0.75495288
108MP0000266_abnormal_heart_morphology0.75197114
109MP0000955_abnormal_spinal_cord0.75179276
110MP0003567_abnormal_fetal_cardiomyocyte0.73016031
111MP0002160_abnormal_reproductive_system0.71484579
112MP0002229_neurodegeneration0.71308658
113MP0005187_abnormal_penis_morphology0.71024385
114MP0004142_abnormal_muscle_tone0.70934507
115MP0000230_abnormal_systemic_arterial0.70672557
116MP0009780_abnormal_chondrocyte_physiolo0.68850097
117MP0005253_abnormal_eye_physiology0.68669376
118MP0005623_abnormal_meninges_morphology0.66384894
119MP0002752_abnormal_somatic_nervous0.62630470
120MP0002152_abnormal_brain_morphology0.61459926
121MP0004043_abnormal_pH_regulation0.61169209
122MP0001905_abnormal_dopamine_level0.59755121
123MP0003633_abnormal_nervous_system0.58205988
124MP0005535_abnormal_body_temperature0.57021629

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)7.16250992
2Atrial fibrillation (HP:0005110)5.97336687
3Primary atrial arrhythmia (HP:0001692)5.69769128
4Supraventricular tachycardia (HP:0004755)5.45755809
5Supraventricular arrhythmia (HP:0005115)5.31929086
6Ventricular tachycardia (HP:0004756)5.22453858
7Syncope (HP:0001279)5.22103428
8Prolonged QT interval (HP:0001657)4.93992189
9Calf muscle hypertrophy (HP:0008981)4.78455613
10Ventricular fibrillation (HP:0001663)4.60956673
11Exercise-induced myalgia (HP:0003738)4.38483150
12Muscle hypertrophy of the lower extremities (HP:0008968)4.32636080
13Bundle branch block (HP:0011710)4.32303423
14Abnormality of the calf musculature (HP:0001430)4.30741377
15Lipoatrophy (HP:0100578)4.05768852
16Hypoglycemic coma (HP:0001325)4.02947685
17Subaortic stenosis (HP:0001682)3.98859472
18Abnormality of the left ventricular outflow tract (HP:0011103)3.98859472
19Exercise-induced muscle cramps (HP:0003710)3.95103687
20Ventricular arrhythmia (HP:0004308)3.93832416
21Focal motor seizures (HP:0011153)3.90987100
22Abnormal EKG (HP:0003115)3.90694650
23Hypoglycemic seizures (HP:0002173)3.80351138
24Palpitations (HP:0001962)3.69447631
25Hyperinsulinemic hypoglycemia (HP:0000825)3.64139819
26Right ventricular cardiomyopathy (HP:0011663)3.58379857
27Muscle fiber splitting (HP:0003555)3.49975931
28Central scotoma (HP:0000603)3.33235988
29Left ventricular hypertrophy (HP:0001712)3.31042265
30Heart block (HP:0012722)3.27960676
31Dilated cardiomyopathy (HP:0001644)3.26691530
32Myokymia (HP:0002411)3.20133786
33Myoglobinuria (HP:0002913)3.05958048
34Hyporeflexia of lower limbs (HP:0002600)3.05430878
35Atrioventricular block (HP:0001678)3.03932781
36Focal seizures (HP:0007359)3.02069631
37Visual hallucinations (HP:0002367)3.00139401
38Abnormal atrioventricular conduction (HP:0005150)2.99690792
39Dysmetric saccades (HP:0000641)2.97880541
40Asymmetric septal hypertrophy (HP:0001670)2.91085142
41EMG: myopathic abnormalities (HP:0003458)2.91068967
42Myotonia (HP:0002486)2.89844293
43Pheochromocytoma (HP:0002666)2.89809494
44Epileptiform EEG discharges (HP:0011182)2.86445592
45Hyperglycemia (HP:0003074)2.84672961
46EEG with generalized epileptiform discharges (HP:0011198)2.79621791
47Hypothermia (HP:0002045)2.73839307
48Epileptic encephalopathy (HP:0200134)2.72676646
49Febrile seizures (HP:0002373)2.70105455
50Hypsarrhythmia (HP:0002521)2.66358339
51Abnormal mitochondria in muscle tissue (HP:0008316)2.63584067
52Acute necrotizing encephalopathy (HP:0006965)2.62497583
53Late onset (HP:0003584)2.61250658
54Abnormality of calcium-phosphate metabolism (HP:0100530)2.57210173
55Large for gestational age (HP:0001520)2.53977039
56Progressive cerebellar ataxia (HP:0002073)2.53746641
57Neuroendocrine neoplasm (HP:0100634)2.49727392
58Insulin-resistant diabetes mellitus (HP:0000831)2.46984253
59Absence seizures (HP:0002121)2.41262139
60Congenital stationary night blindness (HP:0007642)2.41137159
61Limb dystonia (HP:0002451)2.38864318
62Proximal tubulopathy (HP:0000114)2.34660001
63Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.32760128
64Abnormality of alanine metabolism (HP:0010916)2.32760128
65Hyperalaninemia (HP:0003348)2.32760128
66Progressive macrocephaly (HP:0004481)2.30935176
67Ketosis (HP:0001946)2.30623870
68Increased circulating renin level (HP:0000848)2.29108803
69Hemiparesis (HP:0001269)2.26080650
70Atonic seizures (HP:0010819)2.25898011
71Dysdiadochokinesis (HP:0002075)2.24382488
72Abnormality of urine glucose concentration (HP:0011016)2.22557206
73Glycosuria (HP:0003076)2.22557206
74Difficulty running (HP:0009046)2.21529765
75Abnormal pancreas size (HP:0012094)2.19072330
76Broad-based gait (HP:0002136)2.18906773
77Abnormality of endocrine pancreas physiology (HP:0012093)2.16659858
78Abnormality of the pancreatic islet cells (HP:0006476)2.16659858
79Scotoma (HP:0000575)2.15531964
80Mitochondrial inheritance (HP:0001427)2.15285597
81Dialeptic seizures (HP:0011146)2.14947800
82Generalized tonic-clonic seizures (HP:0002069)2.13881116
83Drooling (HP:0002307)2.12088816
84Congenital malformation of the right heart (HP:0011723)2.11367451
85Double outlet right ventricle (HP:0001719)2.11367451
86Hepatocellular necrosis (HP:0001404)2.09708724
87Hepatic necrosis (HP:0002605)2.04834047
88Symptomatic seizures (HP:0011145)2.02955046
89Poor eye contact (HP:0000817)2.01659205
90Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.00591698
91Acute encephalopathy (HP:0006846)1.98079267
92Athetosis (HP:0002305)1.96883962
93Palmoplantar keratoderma (HP:0000982)1.96443554
94Tinnitus (HP:0000360)1.96252816
95Hamartoma of the eye (HP:0010568)1.96140069
96Gaze-evoked nystagmus (HP:0000640)1.95804415
97Impaired social interactions (HP:0000735)1.95687875
98Abnormal social behavior (HP:0012433)1.95687875
99Osteomalacia (HP:0002749)1.94280758
100Rhabdomyolysis (HP:0003201)1.93815863
101Increased CSF lactate (HP:0002490)1.93115972
102Action tremor (HP:0002345)1.93032130
103Hypomagnesemia (HP:0002917)1.91860316
104Genetic anticipation (HP:0003743)1.90323470
105Bradycardia (HP:0001662)1.90269594
106Hyperventilation (HP:0002883)1.89067485
107Ketoacidosis (HP:0001993)1.88399139
108Hyperphosphaturia (HP:0003109)1.88192709
109Excessive salivation (HP:0003781)1.87874754
110Generalized myoclonic seizures (HP:0002123)1.87431308
111Ragged-red muscle fibers (HP:0003200)1.84885102
112Anxiety (HP:0000739)1.84110134
113Depression (HP:0000716)1.80850515
114Tachypnea (HP:0002789)1.79984568
115EMG: neuropathic changes (HP:0003445)1.78900122
116Testicular neoplasm (HP:0010788)1.77993491
117Limb-girdle muscle atrophy (HP:0003797)1.77324303
118Increased connective tissue (HP:0009025)1.77233386
119Enlarged penis (HP:0000040)1.76240192
120Increased intramyocellular lipid droplets (HP:0012240)1.75876016
121Difficulty climbing stairs (HP:0003551)1.75458613
122Polyuria (HP:0000103)1.75062954
123Optic disc pallor (HP:0000543)1.74587307
124Lymphangioma (HP:0100764)1.74364003
125Increased muscle lipid content (HP:0009058)1.73132498
126Sudden cardiac death (HP:0001645)1.73115170
127Neoplasm of the adrenal gland (HP:0100631)1.71806780
128Abnormality of the foot musculature (HP:0001436)1.71601754
129Polydipsia (HP:0001959)1.71397827
130Abnormal drinking behavior (HP:0030082)1.71397827
131Prominent metopic ridge (HP:0005487)1.67524980
132Exercise intolerance (HP:0003546)1.67235522
133Dysmetria (HP:0001310)1.67020164
134Amblyopia (HP:0000646)1.66916716
135Abnormality of macular pigmentation (HP:0008002)1.64714585
136Agitation (HP:0000713)1.64281988
137Muscular hypotonia of the trunk (HP:0008936)1.64281040
138Polyphagia (HP:0002591)1.63755820
139Lactic acidosis (HP:0003128)1.63711578
140Metaphyseal dysplasia (HP:0100255)1.63440500
141Truncal ataxia (HP:0002078)1.61597408
142Disproportionate short-trunk short stature (HP:0003521)1.61107800
143Unsteady gait (HP:0002317)1.60490535
144Hypoplastic left heart (HP:0004383)1.60095006
145Increased variability in muscle fiber diameter (HP:0003557)1.59696016
146Increased serum pyruvate (HP:0003542)1.59366013
147Abnormality of glycolysis (HP:0004366)1.59366013
148Tongue fasciculations (HP:0001308)1.58981409

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.19998203
2PHKG23.39205177
3PHKG13.39205177
4MARK12.79880317
5MYLK2.78158401
6LMTK22.74425267
7MAP3K42.54852125
8TTN2.53894985
9NTRK32.41950513
10EPHA42.34184491
11DMPK2.33681553
12NEK12.30398298
13MAP3K92.24804918
14PAK62.16482167
15STK392.14300632
16PDK32.11516623
17PDK42.11516623
18FGFR22.08970503
19OBSCN2.08828261
20MAP2K71.79819874
21PINK11.79406312
22MINK11.75898062
23MUSK1.75802818
24PAK31.69655648
25OXSR11.68116541
26PKN21.66669583
27STK381.66132075
28STK241.55082093
29CAMK2D1.44670179
30MAP2K41.44260527
31BMPR1B1.42584468
32GRK71.41844238
33CSNK1G21.27905158
34CDC42BPA1.27834539
35DAPK21.27512296
36KSR11.25974322
37CAMK11.24625657
38CAMK2A1.24524079
39PIK3CA1.24422820
40TRIM281.23978202
41STK38L1.21263486
42CASK1.20444849
43PRPF4B1.17344254
44PDK21.16481817
45KSR21.14284994
46CSNK1G11.13312708
47INSRR1.12669063
48PRKD31.11819931
49LATS21.11050952
50NTRK21.10954465
51MAPK131.09960486
52CSNK1G31.05661668
53ACVR1B1.05267449
54CAMK40.99968319
55PASK0.98686075
56RIPK10.98417111
57CAMKK10.97221623
58PRKAA10.95066199
59MAP3K60.93971199
60UHMK10.93881754
61CDK50.91819785
62GRK50.88229749
63SGK20.86697802
64ROCK10.85825607
65ADRBK20.85217322
66PLK20.84375622
67LIMK10.84090969
68SGK2230.83433138
69SGK4940.83433138
70PRKD10.82551955
71STK30.82007432
72MAPK120.80770111
73DAPK30.78933316
74PRKCE0.78877029
75CSNK1A1L0.78017947
76NLK0.76815915
77GRK10.76679379
78ROCK20.76517613
79TIE10.74274548
80MAP3K70.72761090
81BCR0.71766929
82PTK2B0.70844928
83MAP3K120.69335851
84TRPM70.68974331
85MAP3K50.68838406
86NTRK10.68505386
87PNCK0.67297957
88WNK30.66040544
89PKN10.65517769
90SGK30.65313835
91WNK10.64826711
92PRKCH0.64260874
93RET0.64163749
94PRKCG0.63382846
95DYRK1A0.62501405
96CAMKK20.62457033
97ILK0.62111668
98MARK20.60884301
99DAPK10.57240309
100ERBB30.56144212
101STK110.56077765
102PRKACA0.55990591
103SGK10.54548147
104PRKACB0.52762574
105NME10.52707110
106CAMK2G0.52257634
107AKT30.52182990
108FER0.51896029
109DYRK20.50963836
110WNK40.50527019
111CAMK2B0.49637698
112BCKDK0.48456488
113TRIB30.46418267
114RPS6KA30.45163889
115BMPR20.45044101
116PRKCZ0.45029622
117MST40.44854588
118MAP2K60.44538206
119MAP4K20.44377444
120SIK20.44015296
121TNIK0.43303542
122PRKG10.42059099
123MAP2K10.41040963
124HIPK20.39354785
125CDK180.39298842
126ADRBK10.39129489
127PDK10.39012248
128PRKACG0.39009007
129PRKAA20.38906466
130PRKCA0.38787180
131CAMK1G0.38498218
132MKNK20.38056707

Predicted pathways (KEGG)

RankGene SetZ-score
1Cardiac muscle contraction_Homo sapiens_hsa042603.63600437
2Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.59069579
3Dilated cardiomyopathy_Homo sapiens_hsa054142.91405378
4Maturity onset diabetes of the young_Homo sapiens_hsa049502.86495304
5Nicotine addiction_Homo sapiens_hsa050332.78200856
6Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.60677807
72-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.45835846
8Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042612.26458759
9Circadian entrainment_Homo sapiens_hsa047132.19237548
10Parkinsons disease_Homo sapiens_hsa050122.15144111
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.14817978
12Oxidative phosphorylation_Homo sapiens_hsa001902.14675769
13Synaptic vesicle cycle_Homo sapiens_hsa047212.10606776
14GABAergic synapse_Homo sapiens_hsa047272.07143569
15Olfactory transduction_Homo sapiens_hsa047401.99343460
16Morphine addiction_Homo sapiens_hsa050321.96548462
17Glutamatergic synapse_Homo sapiens_hsa047241.93352231
18Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.91979169
19Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.89708617
20Alzheimers disease_Homo sapiens_hsa050101.80201068
21Insulin secretion_Homo sapiens_hsa049111.72081846
22Long-term potentiation_Homo sapiens_hsa047201.69229867
23Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.59174876
24Oxytocin signaling pathway_Homo sapiens_hsa049211.58625380
25Calcium signaling pathway_Homo sapiens_hsa040201.55599022
26Taste transduction_Homo sapiens_hsa047421.54468176
27Salivary secretion_Homo sapiens_hsa049701.52842884
28Cholinergic synapse_Homo sapiens_hsa047251.51096670
29Dopaminergic synapse_Homo sapiens_hsa047281.50790191
30Amphetamine addiction_Homo sapiens_hsa050311.50133825
31Huntingtons disease_Homo sapiens_hsa050161.47483499
32cGMP-PKG signaling pathway_Homo sapiens_hsa040221.46274707
33Renin secretion_Homo sapiens_hsa049241.45303424
34Aldosterone synthesis and secretion_Homo sapiens_hsa049251.38375631
35Gastric acid secretion_Homo sapiens_hsa049711.30442621
36Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.27120884
37Serotonergic synapse_Homo sapiens_hsa047261.22990933
38Type II diabetes mellitus_Homo sapiens_hsa049301.20746261
39cAMP signaling pathway_Homo sapiens_hsa040241.19844882
40Gap junction_Homo sapiens_hsa045401.12421362
41Propanoate metabolism_Homo sapiens_hsa006401.10995131
42Circadian rhythm_Homo sapiens_hsa047101.07672617
43Carbon metabolism_Homo sapiens_hsa012001.07296826
44GnRH signaling pathway_Homo sapiens_hsa049121.06650942
45Long-term depression_Homo sapiens_hsa047301.04535147
46Vascular smooth muscle contraction_Homo sapiens_hsa042701.04237068
47Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.02397767
48Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.98231319
49Regulation of autophagy_Homo sapiens_hsa041400.93476533
50Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.92684588
51Cocaine addiction_Homo sapiens_hsa050300.90128481
52Glucagon signaling pathway_Homo sapiens_hsa049220.88959182
53Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.88670649
54Phototransduction_Homo sapiens_hsa047440.85431033
55Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.82418751
56Bile secretion_Homo sapiens_hsa049760.81914010
57Thyroid hormone signaling pathway_Homo sapiens_hsa049190.80153212
58Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.79806290
59Ether lipid metabolism_Homo sapiens_hsa005650.79033145
60Linoleic acid metabolism_Homo sapiens_hsa005910.77696592
61Pyruvate metabolism_Homo sapiens_hsa006200.76792419
62Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.73189654
63Estrogen signaling pathway_Homo sapiens_hsa049150.72925151
64Axon guidance_Homo sapiens_hsa043600.72262818
65Phosphatidylinositol signaling system_Homo sapiens_hsa040700.71279561
66Collecting duct acid secretion_Homo sapiens_hsa049660.71059329
67Fatty acid degradation_Homo sapiens_hsa000710.69997365
68Butanoate metabolism_Homo sapiens_hsa006500.69676427
69Insulin signaling pathway_Homo sapiens_hsa049100.68616061
70Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.67007753
71Viral myocarditis_Homo sapiens_hsa054160.65771249
72Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.65540898
73Pancreatic secretion_Homo sapiens_hsa049720.64079472
74Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.63614944
75Fatty acid metabolism_Homo sapiens_hsa012120.61463906
76Melanogenesis_Homo sapiens_hsa049160.58372547
77Tryptophan metabolism_Homo sapiens_hsa003800.56887612
78Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56847192
79alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.55950665
80ErbB signaling pathway_Homo sapiens_hsa040120.55711803
81Oocyte meiosis_Homo sapiens_hsa041140.55453863
82Longevity regulating pathway - mammal_Homo sapiens_hsa042110.55186759
83Phospholipase D signaling pathway_Homo sapiens_hsa040720.54499499
84Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.54110314
85Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.53938139
86HIF-1 signaling pathway_Homo sapiens_hsa040660.53710735
87mTOR signaling pathway_Homo sapiens_hsa041500.53668491
88Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.53470477
89Dorso-ventral axis formation_Homo sapiens_hsa043200.51619628
90Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.51209581
91VEGF signaling pathway_Homo sapiens_hsa043700.50941164
92MAPK signaling pathway_Homo sapiens_hsa040100.50016734
93Central carbon metabolism in cancer_Homo sapiens_hsa052300.49352143
94Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48306785
95Glioma_Homo sapiens_hsa052140.47410915
96Hedgehog signaling pathway_Homo sapiens_hsa043400.46650693
97Ovarian steroidogenesis_Homo sapiens_hsa049130.46295161
98Biosynthesis of amino acids_Homo sapiens_hsa012300.45907883
99Fatty acid elongation_Homo sapiens_hsa000620.45221022
100Mineral absorption_Homo sapiens_hsa049780.44847840
101Renal cell carcinoma_Homo sapiens_hsa052110.44754641
102ABC transporters_Homo sapiens_hsa020100.44184303
103Choline metabolism in cancer_Homo sapiens_hsa052310.43861566
104Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.42630828
105Inositol phosphate metabolism_Homo sapiens_hsa005620.41112040
106Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.40494782
107AMPK signaling pathway_Homo sapiens_hsa041520.40478686
108Tight junction_Homo sapiens_hsa045300.40306666
109Insulin resistance_Homo sapiens_hsa049310.40272934
110beta-Alanine metabolism_Homo sapiens_hsa004100.39743079
111Endometrial cancer_Homo sapiens_hsa052130.36352391
112Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.34420214
113Vitamin B6 metabolism_Homo sapiens_hsa007500.33845026
114Hippo signaling pathway_Homo sapiens_hsa043900.33751803
115Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.33247060
116Peroxisome_Homo sapiens_hsa041460.31633551
117Ras signaling pathway_Homo sapiens_hsa040140.31527313
118Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31250211
119Protein digestion and absorption_Homo sapiens_hsa049740.30458923
120Rap1 signaling pathway_Homo sapiens_hsa040150.28877149
121Carbohydrate digestion and absorption_Homo sapiens_hsa049730.28698423
122Thyroid hormone synthesis_Homo sapiens_hsa049180.28136566
123Focal adhesion_Homo sapiens_hsa045100.27370545
124Vibrio cholerae infection_Homo sapiens_hsa051100.25770607

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