MUC13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intestinal absorption (GO:0050892)8.59523085
2intestinal cholesterol absorption (GO:0030299)7.79201545
3angiotensin maturation (GO:0002003)7.46256328
4regulation of guanylate cyclase activity (GO:0031282)6.71151621
5UDP-N-acetylglucosamine metabolic process (GO:0006047)6.44177680
6NADH metabolic process (GO:0006734)5.57587332
7bundle of His cell to Purkinje myocyte communication (GO:0086069)5.41995206
8epoxygenase P450 pathway (GO:0019373)5.33657115
9positive regulation of guanylate cyclase activity (GO:0031284)5.00762763
10L-fucose catabolic process (GO:0042355)4.95081636
11fucose catabolic process (GO:0019317)4.95081636
12L-fucose metabolic process (GO:0042354)4.95081636
13actin filament depolymerization (GO:0030042)4.93172401
14vitamin A metabolic process (GO:0006776)4.92171558
15cellular glucuronidation (GO:0052695)4.85312920
16regulation of cellular extravasation (GO:0002691)4.85267536
17positive regulation of respiratory burst (GO:0060267)4.84031463
18uronic acid metabolic process (GO:0006063)4.76910427
19glucuronate metabolic process (GO:0019585)4.76910427
20thrombin receptor signaling pathway (GO:0070493)4.68514328
21hepatocyte apoptotic process (GO:0097284)4.60212256
22regulation of systemic arterial blood pressure by hormone (GO:0001990)4.58474977
23regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)4.58474977
24endocrine process (GO:0050886)4.58474977
25fat-soluble vitamin biosynthetic process (GO:0042362)4.53710693
263-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)4.47973692
27purine ribonucleoside bisphosphate metabolic process (GO:0034035)4.47973692
28flavonoid metabolic process (GO:0009812)4.47770456
29urea cycle (GO:0000050)4.45710852
30antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.43102295
31antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.43102295
32glucose 6-phosphate metabolic process (GO:0051156)4.30902158
33regulation of RIG-I signaling pathway (GO:0039535)4.29069900
34urea metabolic process (GO:0019627)4.27093017
35receptor guanylyl cyclase signaling pathway (GO:0007168)4.23983788
36peptide hormone processing (GO:0016486)4.23962233
37regulation of systemic arterial blood pressure (GO:0003073)4.18609990
38lipoprotein transport (GO:0042953)4.17519240
39regulation of cGMP biosynthetic process (GO:0030826)4.12812733
40hormone catabolic process (GO:0042447)4.12809118
41drug metabolic process (GO:0017144)4.11606750
42regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)4.11335800
43diacylglycerol metabolic process (GO:0046339)4.04010428
44sulfate transmembrane transport (GO:1902358)4.00886311
45positive regulation of pseudopodium assembly (GO:0031274)3.97599153
46ribosomal small subunit assembly (GO:0000028)3.97339672
47phospholipid scrambling (GO:0017121)3.94655457
48glomerular filtration (GO:0003094)3.92543577
49nitrogen cycle metabolic process (GO:0071941)3.91483193
50hemidesmosome assembly (GO:0031581)3.89753165
51thyroid hormone metabolic process (GO:0042403)3.88045519
52ethanol oxidation (GO:0006069)3.86491309
53bile acid and bile salt transport (GO:0015721)3.85592990
54* digestive system process (GO:0022600)3.84337132
55fructose metabolic process (GO:0006000)3.81387871
56renal system process involved in regulation of blood volume (GO:0001977)3.80148052
57regulation of vitamin metabolic process (GO:0030656)3.77586155
58arginine metabolic process (GO:0006525)3.77091764
59phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.76113619
60auditory receptor cell differentiation (GO:0042491)3.73458952
61purine nucleotide salvage (GO:0032261)3.65969122
62intestinal epithelial cell development (GO:0060576)3.65733094
63transcytosis (GO:0045056)3.64164600
64sulfation (GO:0051923)3.64002935
65complement activation, classical pathway (GO:0006958)3.63058570
66regulation of respiratory burst (GO:0060263)3.62957999
67calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.58147981
68regulation of pseudopodium assembly (GO:0031272)3.57963390
69antigen processing and presentation of endogenous antigen (GO:0019883)3.57307910
70renal filtration (GO:0097205)3.57148695
71regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)3.54726332
72glycosphingolipid catabolic process (GO:0046479)3.53134116
73very-low-density lipoprotein particle assembly (GO:0034379)3.52795025
74* O-glycan processing (GO:0016266)3.52276243
75glycolipid catabolic process (GO:0019377)3.51470964
76hydrogen peroxide catabolic process (GO:0042744)3.50204690
77response to hepatocyte growth factor (GO:0035728)3.46742546
78cellular response to hepatocyte growth factor stimulus (GO:0035729)3.46742546
79drug catabolic process (GO:0042737)3.46372165
80nucleotide-sugar metabolic process (GO:0009225)3.45607179
81vitamin transmembrane transport (GO:0035461)3.42463511
82regulation of cholesterol homeostasis (GO:2000188)3.41117793
83antimicrobial humoral response (GO:0019730)3.40034510
84antibacterial humoral response (GO:0019731)3.39367222
85regulation of cGMP metabolic process (GO:0030823)3.37193285
86oligosaccharide biosynthetic process (GO:0009312)3.34094590
87adhesion of symbiont to host cell (GO:0044650)3.32126209
88virion attachment to host cell (GO:0019062)3.32126209
89production of molecular mediator involved in inflammatory response (GO:0002532)3.31087452
90regulation of viral entry into host cell (GO:0046596)3.26262441
91regulation of bile acid biosynthetic process (GO:0070857)3.24367168
92sulfate transport (GO:0008272)3.24094571
93sulfur compound transport (GO:0072348)3.22829645
94regulation of actin nucleation (GO:0051125)3.22159708
95definitive hemopoiesis (GO:0060216)3.21555981
96activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO3.21130031
97regulation of viral release from host cell (GO:1902186)3.21099937
98digestion (GO:0007586)3.19976975
99positive regulation of glycoprotein metabolic process (GO:1903020)3.19805578
100antigen processing and presentation via MHC class Ib (GO:0002475)3.18809292
101fucose metabolic process (GO:0006004)3.18782828
102galactose catabolic process (GO:0019388)3.18665325
103Arp2/3 complex-mediated actin nucleation (GO:0034314)3.16547478
104actin nucleation (GO:0045010)3.16314152
105GDP-mannose metabolic process (GO:0019673)3.14907688
106eosinophil chemotaxis (GO:0048245)3.14531817
107mature B cell differentiation involved in immune response (GO:0002313)3.14227659
108nucleoside diphosphate biosynthetic process (GO:0009133)3.13648186
109striated muscle atrophy (GO:0014891)3.13092755
110sperm capacitation (GO:0048240)3.12852799
111ethanol metabolic process (GO:0006067)3.12840756
112fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.12409929
113regulation of extracellular matrix disassembly (GO:0010715)3.12172197
114vitamin transport (GO:0051180)3.11698745
115phospholipid efflux (GO:0033700)3.11101998
116glutamine family amino acid biosynthetic process (GO:0009084)3.10748850
117glycosylceramide metabolic process (GO:0006677)3.05623876
118modified amino acid transport (GO:0072337)3.05293773
119drug transmembrane transport (GO:0006855)3.03714975
120alkaloid metabolic process (GO:0009820)3.02016125
121negative regulation of viral entry into host cell (GO:0046597)3.01951668
122plasma lipoprotein particle assembly (GO:0034377)3.01828926
123exogenous drug catabolic process (GO:0042738)2.99348464
124bile acid metabolic process (GO:0008206)2.98696746
125sphingolipid catabolic process (GO:0030149)2.98359607
126cGMP-mediated signaling (GO:0019934)2.95915243
127drug transport (GO:0015893)2.95492334
128hexose catabolic process (GO:0019320)2.94907187
129positive regulation of cGMP biosynthetic process (GO:0030828)2.94334047
130positive regulation of lipid catabolic process (GO:0050996)2.92485798
131arginine catabolic process (GO:0006527)2.91595735
132ceramide catabolic process (GO:0046514)2.90650288
133complement activation (GO:0006956)2.90016820
134nucleotide salvage (GO:0043173)2.87167959
135regulation of triglyceride catabolic process (GO:0010896)2.86295772
136viral transcription (GO:0019083)2.84930734
137phenylpropanoid metabolic process (GO:0009698)2.84859312
138regulation of membrane lipid distribution (GO:0097035)2.84321437
139hydrogen peroxide metabolic process (GO:0042743)2.82210863
140nucleotide-sugar biosynthetic process (GO:0009226)2.81689948
141histamine transport (GO:0051608)2.81223309
142antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.81128136
143protein-lipid complex assembly (GO:0065005)2.80538224
144membrane lipid catabolic process (GO:0046466)2.79752975
145midgut development (GO:0007494)2.79128530
146renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)2.78930327
147peptide catabolic process (GO:0043171)2.76379016
148detection of bacterium (GO:0016045)2.76351966
149positive regulation of glycoprotein biosynthetic process (GO:0010560)2.75368070
150* maintenance of gastrointestinal epithelium (GO:0030277)2.75118782
151lipoprotein metabolic process (GO:0042157)2.74652322
152muscle atrophy (GO:0014889)2.73302779
153response to hydroperoxide (GO:0033194)2.72454419
154sphingomyelin metabolic process (GO:0006684)2.71417876
155positive regulation of lipoprotein lipase activity (GO:0051006)2.69972173
156positive regulation of triglyceride lipase activity (GO:0061365)2.69972173
157translational termination (GO:0006415)2.69676412
158regulation of proton transport (GO:0010155)2.69289564
159negative regulation of T cell receptor signaling pathway (GO:0050860)2.67787247
160adhesion of symbiont to host (GO:0044406)2.64956978
161innate immune response in mucosa (GO:0002227)2.64762835
162regulation of T cell receptor signaling pathway (GO:0050856)2.64631235
163lipopolysaccharide biosynthetic process (GO:0009103)2.63665678
164execution phase of apoptosis (GO:0097194)2.62452300
165skeletal muscle adaptation (GO:0043501)2.62193259
166mucosal-associated lymphoid tissue development (GO:0048537)2.60202244
167Peyers patch development (GO:0048541)2.60202244

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human6.10963424
2* CDX2_20551321_ChIP-Seq_CACO-2_Human4.36531350
3E2F7_22180533_ChIP-Seq_HELA_Human4.14702942
4SOX2_27498859_Chip-Seq_STOMACH_Mouse3.02080729
5GATA1_22025678_ChIP-Seq_K562_Human2.88835124
6IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.82691240
7SCL_19346495_ChIP-Seq_HPC-7_Human2.76733677
8* HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.65508518
9* GATA4_25053715_ChIP-Seq_YYC3_Human2.58226682
10IRF8_22096565_ChIP-ChIP_GC-B_Human2.57670791
11LXR_22158963_ChIP-Seq_LIVER_Mouse2.54523229
12TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.49734531
13* GATA6_25053715_ChIP-Seq_YYC3_Human2.44454381
14CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.41877363
15RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.37091917
16* SOX2_20726797_ChIP-Seq_SW620_Human2.23026510
17STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.22979945
18TRIM28_21343339_ChIP-Seq_HEK293_Human2.20898090
19* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.19230842
20SRY_22984422_ChIP-ChIP_TESTIS_Rat2.13995525
21CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.12068085
22MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.12020753
23FOXO3_23340844_ChIP-Seq_DLD1_Human2.09699009
24RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.07736046
25FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.03817051
26SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.03724265
27LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.91757558
28EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.91590286
29GATA1_22383799_ChIP-Seq_G1ME_Mouse1.88477117
30SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.87869184
31VDR_21846776_ChIP-Seq_THP-1_Human1.84734778
32RUNX1_22412390_ChIP-Seq_EML_Mouse1.81203581
33VDR_24763502_ChIP-Seq_THP-1_Human1.79987020
34AR_21909140_ChIP-Seq_LNCAP_Human1.79124174
35BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.77026926
36TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.75771771
37ESR1_21235772_ChIP-Seq_MCF-7_Human1.70719571
38LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.67636774
39* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.64533058
40AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.64381520
41RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.63132220
42SPI1_23547873_ChIP-Seq_NB4_Human1.59016873
43KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.56878621
44PPARA_22158963_ChIP-Seq_LIVER_Mouse1.55866939
45PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.55357503
46ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.54307684
47ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.49955523
48ESR2_21235772_ChIP-Seq_MCF-7_Human1.48543497
49* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.47741567
50FOXA1_25552417_ChIP-Seq_VCAP_Human1.46650407
51IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.45835678
52GATA2_19941826_ChIP-Seq_K562_Human1.44816070
53FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.43042160
54THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.42768549
55FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.41364294
56ELF1_17652178_ChIP-ChIP_JURKAT_Human1.40429027
57LXR_22292898_ChIP-Seq_THP-1_Human1.39670330
58FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.37997982
59TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.37414849
60PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.34711834
61HNF4A_19822575_ChIP-Seq_HepG2_Human1.33663887
62* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.32965848
63TCF7_22412390_ChIP-Seq_EML_Mouse1.31291440
64FOXA2_19822575_ChIP-Seq_HepG2_Human1.31089179
65NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.30741218
66STAT4_19710469_ChIP-ChIP_TH1__Mouse1.29388953
67BP1_19119308_ChIP-ChIP_Hs578T_Human1.29199152
68* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.29025383
69GATA1_19941827_ChIP-Seq_MEL_Mouse1.28526006
70CDX2_22108803_ChIP-Seq_LS180_Human1.28318597
71ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.28206462
72PPAR_26484153_Chip-Seq_NCI-H1993_Human1.24119920
73ATF3_27146783_Chip-Seq_COLON_Human1.22515986
74SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.22435283
75CLOCK_20551151_ChIP-Seq_293T_Human1.21377548
76FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.21315632
77NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.20766667
78NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.19871584
79RACK7_27058665_Chip-Seq_MCF-7_Human1.19560553
80MYB_26560356_Chip-Seq_TH2_Human1.19364559
81MAF_26560356_Chip-Seq_TH1_Human1.19199307
82RUNX1_27514584_Chip-Seq_MCF-7_Human1.18834947
83SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.17911401
84UTX_26944678_Chip-Seq_JUKART_Human1.17175392
85KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.17166721
86STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.17086116
87ZNF263_19887448_ChIP-Seq_K562_Human1.16348519
88KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.15884745
89STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.15217869
90CDX2_19796622_ChIP-Seq_MESCs_Mouse1.13957102
91NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.13650686
92* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.13489583
93* KLF5_25053715_ChIP-Seq_YYC3_Human1.13397106
94SPI1_23127762_ChIP-Seq_K562_Human1.12988063
95SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.12979733
96ELF5_23300383_ChIP-Seq_T47D_Human1.11947458
97EGR1_23403033_ChIP-Seq_LIVER_Mouse1.10263255
98P63_26484246_Chip-Seq_KERATINOCYTES_Human1.10247046
99RXR_22158963_ChIP-Seq_LIVER_Mouse1.09647343
100MYB_26560356_Chip-Seq_TH1_Human1.09497681
101STAT3_1855785_ChIP-Seq_MESCs_Mouse1.09309339
102PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.08893183
103BCL6_27268052_Chip-Seq_Bcells_Human1.08785429
104ERG_20887958_ChIP-Seq_HPC-7_Mouse1.07126875
105E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.06822808
106MYC_18555785_ChIP-Seq_MESCs_Mouse1.06343692
107PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.04625441
108DROSHA_22980978_ChIP-Seq_HELA_Human1.04613744
109* EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.04559693
110ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.04208676
111MYC_22102868_ChIP-Seq_BL_Human1.03085366
112GATA2_21666600_ChIP-Seq_HMVEC_Human1.02618381
113BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.02130042
114SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.01870183
115SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.01870183
116GATA3_24758297_ChIP-Seq_MCF-7_Human1.01734486
117MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.00198052
118GATA1_19941826_ChIP-Seq_K562_Human0.99867170
119HOXB4_20404135_ChIP-ChIP_EML_Mouse0.98007918
120EGR1_19374776_ChIP-ChIP_THP-1_Human0.97225129
121SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97056750
122IRF8_21731497_ChIP-ChIP_J774_Mouse0.97020878
123JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.96313991
124TCF4_18268006_ChIP-ChIP_LS174T_Human0.96036769
125CEBPB_22108803_ChIP-Seq_LS180_Human0.95260146
126ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.94930927
127FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.94580750
128SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.92819812
129ELK3_25401928_ChIP-Seq_HUVEC_Human0.92255918
130SA1_27219007_Chip-Seq_Bcells_Human0.90990706
131BCOR_27268052_Chip-Seq_Bcells_Human0.90926469
132NANOG_20526341_ChIP-Seq_ESCs_Human0.90749987
133CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90585077
134RARG_19884340_ChIP-ChIP_MEFs_Mouse0.89706983
135IRF8_27001747_Chip-Seq_BMDM_Mouse0.88931918
136RAD21_21589869_ChIP-Seq_MESCs_Mouse0.87161527
137SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.86957804
138ZNF217_24962896_ChIP-Seq_MCF-7_Human0.86916238
139TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.85923947
140TET1_21451524_ChIP-Seq_MESCs_Mouse0.85183620
141STAT1_20625510_ChIP-Seq_HELA_Human0.84832326
142CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.82332578
143Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.82198120
144FOXA1_21572438_ChIP-Seq_LNCaP_Human0.80933671
145CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.80785331
146CTCF_27219007_Chip-Seq_Bcells_Human0.80321980
147BCAT_22108803_ChIP-Seq_LS180_Human0.79989364
148EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.77761299
149CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.76981611
150VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.76321222
151* PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.73874221
152* TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.73555822
153TP63_22573176_ChIP-Seq_HFKS_Human0.72750294
154FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.71734110
155TP63_23658742_ChIP-Seq_EP156T_Human0.69203411
156KAP1_22055183_ChIP-Seq_ESCs_Mouse0.68709115

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis5.41983182
2MP0010234_abnormal_vibrissa_follicle4.99667028
3MP0001666_abnormal_nutrient_absorption4.46173365
4MP0003866_abnormal_defecation4.09798151
5MP0004264_abnormal_extraembryonic_tissu4.00015880
6MP0001873_stomach_inflammation3.21738887
7MP0004147_increased_porphyrin_level3.10108494
8MP0010155_abnormal_intestine_physiology3.01657395
9MP0000490_abnormal_crypts_of2.98982036
10MP0000462_abnormal_digestive_system2.75010488
11MP0001663_abnormal_digestive_system2.61481943
12MP0006054_spinal_hemorrhage2.41507216
13MP0005085_abnormal_gallbladder_physiolo2.39241475
14MP0005381_digestive/alimentary_phenotyp2.28157116
15MP0010352_gastrointestinal_tract_polyps2.27141104
16MP0003183_abnormal_peptide_metabolism2.21062519
17MP0000477_abnormal_intestine_morphology2.11346091
18MP0009379_abnormal_foot_pigmentation2.05151388
19MP0008875_abnormal_xenobiotic_pharmacok2.04496680
20MP0002138_abnormal_hepatobiliary_system2.03761095
21MP0009840_abnormal_foam_cell1.98117128
22MP0002396_abnormal_hematopoietic_system1.93553541
23MP0005332_abnormal_amino_acid1.91891605
24MP0003252_abnormal_bile_duct1.86589653
25MP0000465_gastrointestinal_hemorrhage1.85644150
26MP0002822_catalepsy1.85058656
27MP0001664_abnormal_digestion1.80077293
28MP0005409_darkened_coat_color1.79618249
29MP0002139_abnormal_hepatobiliary_system1.70502586
30MP0003300_gastrointestinal_ulcer1.68412592
31MP0009785_altered_susceptibility_to1.66105040
32MP0005464_abnormal_platelet_physiology1.65594089
33MP0004782_abnormal_surfactant_physiolog1.62672805
34MP0003878_abnormal_ear_physiology1.61190112
35MP0005377_hearing/vestibular/ear_phenot1.61190112
36MP0000537_abnormal_urethra_morphology1.59279552
37MP0010329_abnormal_lipoprotein_level1.58104764
38MP0005174_abnormal_tail_pigmentation1.57607723
39MP0003693_abnormal_embryo_hatching1.51027993
40MP0005365_abnormal_bile_salt1.47284741
41MP0004858_abnormal_nervous_system1.41412079
42MP0004947_skin_inflammation1.33887830
43MP0001756_abnormal_urination1.33276678
44MP0005025_abnormal_response_to1.29290980
45MP0003724_increased_susceptibility_to1.29144669
46MP0003879_abnormal_hair_cell1.27351886
47MP0000678_abnormal_parathyroid_gland1.26583632
48MP0005397_hematopoietic_system_phenotyp1.24446200
49MP0001545_abnormal_hematopoietic_system1.24446200
50MP0002136_abnormal_kidney_physiology1.24412678
51MP0002876_abnormal_thyroid_physiology1.23161195
52MP0005084_abnormal_gallbladder_morpholo1.22608867
53MP0002118_abnormal_lipid_homeostasis1.21868546
54MP0001849_ear_inflammation1.16511130
55MP0003191_abnormal_cellular_cholesterol1.16449054
56MP0000538_abnormal_urinary_bladder1.16222619
57MP0010678_abnormal_skin_adnexa1.15997175
58MP0001835_abnormal_antigen_presentation1.10699948
59MP0002166_altered_tumor_susceptibility1.07533294
60MP0005671_abnormal_response_to1.06108743
61MP0005167_abnormal_blood-brain_barrier1.04936362
62MP0002148_abnormal_hypersensitivity_rea1.03642445
63MP0003868_abnormal_feces_composition1.02905580
64MP0005058_abnormal_lysosome_morphology1.02746705
65MP0008872_abnormal_physiological_respon1.02011597
66MP0001501_abnormal_sleep_pattern1.01902436
67MP0005670_abnormal_white_adipose1.01896622
68MP0005166_decreased_susceptibility_to1.01446373
69MP0005451_abnormal_body_composition0.98189258
70MP0001845_abnormal_inflammatory_respons0.97762526
71MP0004270_analgesia0.97600397
72MP0009333_abnormal_splenocyte_physiolog0.97578715
73MP0001765_abnormal_ion_homeostasis0.96800561
74MP0003806_abnormal_nucleotide_metabolis0.96244062
75MP0004043_abnormal_pH_regulation0.95648567
76MP0001819_abnormal_immune_cell0.94477230
77MP0009643_abnormal_urine_homeostasis0.93642692
78MP0005310_abnormal_salivary_gland0.93636882
79MP0002796_impaired_skin_barrier0.93452087
80MP0005584_abnormal_enzyme/coenzyme_acti0.91731982
81MP0004019_abnormal_vitamin_homeostasis0.91711369
82MP0003436_decreased_susceptibility_to0.91124910
83MP0002089_abnormal_postnatal_growth/wei0.90967960
84MP0002971_abnormal_brown_adipose0.90861880
85MP0002452_abnormal_antigen_presenting0.90084165
86MP0000230_abnormal_systemic_arterial0.90007935
87MP0002420_abnormal_adaptive_immunity0.90004273
88MP0004808_abnormal_hematopoietic_stem0.89064073
89MP0000013_abnormal_adipose_tissue0.87115333
90MP0004957_abnormal_blastocyst_morpholog0.85976831
91MP0003329_amyloid_beta_deposits0.85315864
92MP0005501_abnormal_skin_physiology0.84773471
93MP0002006_tumorigenesis0.84595633
94MP0005636_abnormal_mineral_homeostasis0.83337585
95MP0002398_abnormal_bone_marrow0.82832033
96MP0001800_abnormal_humoral_immune0.82016657
97MP0008873_increased_physiological_sensi0.81777979
98MP0000467_abnormal_esophagus_morphology0.81665206
99MP0002132_abnormal_respiratory_system0.80811461
100MP0000470_abnormal_stomach_morphology0.80723126
101MP0002909_abnormal_adrenal_gland0.80679461
102MP0005535_abnormal_body_temperature0.79546677
103MP0003315_abnormal_perineum_morphology0.79156685
104MP0002723_abnormal_immune_serum0.75697477
105MP0005319_abnormal_enzyme/_coenzyme0.75543667
106MP0009780_abnormal_chondrocyte_physiolo0.75530421
107MP0003763_abnormal_thymus_physiology0.75433283
108MP0009697_abnormal_copulation0.75320126
109MP0002429_abnormal_blood_cell0.75238079
110MP0002419_abnormal_innate_immunity0.75220619
111MP0001216_abnormal_epidermal_layer0.74797667
112MP0002896_abnormal_bone_mineralization0.74576498
113MP0001188_hyperpigmentation0.73804662
114MP0006082_CNS_inflammation0.73735802
115MP0000609_abnormal_liver_physiology0.72827619
116MP0000685_abnormal_immune_system0.72776342
117MP0000604_amyloidosis0.72660320
118MP0009642_abnormal_blood_homeostasis0.72656456
119MP0002078_abnormal_glucose_homeostasis0.72474328
120MP0008469_abnormal_protein_level0.72395039
121MP0000716_abnormal_immune_system0.72176873
122MP0010307_abnormal_tumor_latency0.72161069
123MP0001764_abnormal_homeostasis0.70973108
124MP0003705_abnormal_hypodermis_morpholog0.69601198
125MP0002722_abnormal_immune_system0.69189103
126MP0005448_abnormal_energy_balance0.69147759
127MP0003303_peritoneal_inflammation0.68923605
128MP0005165_increased_susceptibility_to0.68430700
129MP0001485_abnormal_pinna_reflex0.68427436
130MP0002098_abnormal_vibrissa_morphology0.67068772
131MP0001790_abnormal_immune_system0.66928654
132MP0005387_immune_system_phenotype0.66928654
133MP0003953_abnormal_hormone_level0.66820493
134MP0009115_abnormal_fat_cell0.65724726
135MP0003453_abnormal_keratinocyte_physiol0.64646708
136MP0003283_abnormal_digestive_organ0.58013434
137MP0008004_abnormal_stomach_pH0.56815015
138MP0001881_abnormal_mammary_gland0.56149091
139MP0000566_synostosis0.54721214
140MP0003045_fibrosis0.54244858
141MP0003075_altered_response_to0.53862554

Predicted human phenotypes

RankGene SetZ-score
1Ileus (HP:0002595)6.54254203
2Right ventricular cardiomyopathy (HP:0011663)5.06678204
3Acanthocytosis (HP:0001927)4.90767981
4Decreased circulating renin level (HP:0003351)4.59425615
5Petechiae (HP:0000967)4.53829121
6Systemic lupus erythematosus (HP:0002725)4.24216785
7Abnormality of monocarboxylic acid metabolism (HP:0010996)4.17311880
8Chronic diarrhea (HP:0002028)4.06056626
9Abnormality of renin-angiotensin system (HP:0000847)4.00881806
10Malnutrition (HP:0004395)3.96097391
11Alkalosis (HP:0001948)3.93530597
12Pustule (HP:0200039)3.90896363
13Abnormality of glutamine family amino acid metabolism (HP:0010902)3.83618249
14Conjugated hyperbilirubinemia (HP:0002908)3.74562536
15Autoimmune thrombocytopenia (HP:0001973)3.71374856
16Abnormality of vitamin metabolism (HP:0100508)3.66052930
17Onycholysis (HP:0001806)3.64120527
18Abnormality of small intestinal villus morphology (HP:0011472)3.58189344
19Villous atrophy (HP:0011473)3.58189344
20Abdominal distention (HP:0003270)3.55662409
21Milia (HP:0001056)3.52585363
22Hypobetalipoproteinemia (HP:0003563)3.49466827
23Thrombocytosis (HP:0001894)3.49083024
24Congenital sensorineural hearing impairment (HP:0008527)3.45534880
25Widely patent fontanelles and sutures (HP:0004492)3.44872368
26Flat acetabular roof (HP:0003180)3.34036726
27Autoimmune hemolytic anemia (HP:0001890)3.32051519
28Reduced antithrombin III activity (HP:0001976)3.23674413
29Poikilocytosis (HP:0004447)3.05909692
30Abnormal platelet function (HP:0011869)3.01967328
31Impaired platelet aggregation (HP:0003540)3.01967328
32Proximal tubulopathy (HP:0000114)3.00832400
33Hyperactive renin-angiotensin system (HP:0000841)2.97282701
34Cupped ribs (HP:0000887)2.95407912
35Glomerulonephritis (HP:0000099)2.94842664
36Aplastic anemia (HP:0001915)2.94049510
37Xanthomatosis (HP:0000991)2.93125396
38Woolly hair (HP:0002224)2.90112068
39Confusion (HP:0001289)2.89762028
40Hydroxyprolinuria (HP:0003080)2.87402129
41Abnormality of proline metabolism (HP:0010907)2.87402129
42Hemorrhage of the eye (HP:0011885)2.87103520
43Microretrognathia (HP:0000308)2.84928307
44Thin bony cortex (HP:0002753)2.82529636
45Fragile nails (HP:0001808)2.81506049
46Fat malabsorption (HP:0002630)2.81391286
47Dehydration (HP:0001944)2.80058538
48Palpitations (HP:0001962)2.79256017
49Pili torti (HP:0003777)2.79049081
50Increased mean platelet volume (HP:0011877)2.77836777
51Abnormal platelet volume (HP:0011876)2.74535007
52Chronic otitis media (HP:0000389)2.71448806
53Hyperammonemia (HP:0001987)2.71116191
54Hypotension (HP:0002615)2.67492260
55Gout (HP:0001997)2.64170259
56Gastrointestinal dysmotility (HP:0002579)2.63957888
57Increased purine levels (HP:0004368)2.63009613
58Hyperuricemia (HP:0002149)2.63009613
59Focal segmental glomerulosclerosis (HP:0000097)2.60891646
60Ureteral stenosis (HP:0000071)2.60422724
61Prostate neoplasm (HP:0100787)2.59935294
62Complement deficiency (HP:0004431)2.58099412
63Hyperaldosteronism (HP:0000859)2.57529147
64Increased IgE level (HP:0003212)2.56358363
65Hyperphosphatemia (HP:0002905)2.53977887
66Hyperglycinuria (HP:0003108)2.53317121
67Abnormality of complement system (HP:0005339)2.52358840
68Nausea (HP:0002018)2.51791786
69Micronodular cirrhosis (HP:0001413)2.50710106
70Steatorrhea (HP:0002570)2.48582015
71Nephrolithiasis (HP:0000787)2.47739293
72Abnormal biliary tract morphology (HP:0012440)2.46736464
73Hyperparathyroidism (HP:0000843)2.46586551
74Abnormality of cells of the erythroid lineage (HP:0012130)2.44543385
75Atrophic scars (HP:0001075)2.44201970
76Eczematoid dermatitis (HP:0000976)2.44109252
77Wide cranial sutures (HP:0010537)2.43139743
78Abnormal number of erythroid precursors (HP:0012131)2.42464768
79Goiter (HP:0000853)2.42033333
80Late onset (HP:0003584)2.41643675
81Hypophosphatemia (HP:0002148)2.38881164
82Abnormal tarsal ossification (HP:0008369)2.38561976
83Ureteral obstruction (HP:0006000)2.38004443
84IgM deficiency (HP:0002850)2.34805023
85Nephritis (HP:0000123)2.33656323
86B lymphocytopenia (HP:0010976)2.30599740
87Abnormality of B cell number (HP:0010975)2.30599740
88Rectal prolapse (HP:0002035)2.30580134
89Protuberant abdomen (HP:0001538)2.29442066
90Abnormality of the gastric mucosa (HP:0004295)2.28654924
91Abnormality of serine family amino acid metabolism (HP:0010894)2.28393575
92Abnormality of glycine metabolism (HP:0010895)2.28393575
93Biliary tract neoplasm (HP:0100574)2.26922073
94Prolonged bleeding time (HP:0003010)2.25201521
95Neoplasm of the rectum (HP:0100743)2.23836418
96Elevated erythrocyte sedimentation rate (HP:0003565)2.22457544
97Cheilitis (HP:0100825)2.22206360
98Abnormal protein glycosylation (HP:0012346)2.21993131
99Abnormal glycosylation (HP:0012345)2.21993131
100Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.21993131
101Abnormal protein N-linked glycosylation (HP:0012347)2.21993131
102Hypokalemia (HP:0002900)2.21360035
103Abnormality of purine metabolism (HP:0004352)2.20927962
104Type I transferrin isoform profile (HP:0003642)2.20614439
105Neoplasm of the small intestine (HP:0100833)2.19794713
106Pigmentary retinal degeneration (HP:0001146)2.19776763
107Abnormality of the 1st metacarpal (HP:0010009)2.19509915
108Abnormality of nucleobase metabolism (HP:0010932)2.17868810
109Abnormality of dicarboxylic acid metabolism (HP:0010995)2.16751464
110Dicarboxylic aciduria (HP:0003215)2.16751464
111Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.16598898
112Plantar hyperkeratosis (HP:0007556)2.16351380
113Potter facies (HP:0002009)2.16214023
114Facial shape deformation (HP:0011334)2.16214023
115Poikiloderma (HP:0001029)2.15880323
116Abnormal glucose tolerance (HP:0001952)2.15688922
117Abnormality of the prostate (HP:0008775)2.14335234
118Glomerulosclerosis (HP:0000096)2.14295132
119Hypolipoproteinemia (HP:0010981)2.12366051
120Vascular calcification (HP:0004934)2.11481456
121Abnormality of pyrimidine metabolism (HP:0004353)2.11194295
122Abnormality of the vitamin B12 metabolism (HP:0004341)2.10772215
123Abnormality of chloride homeostasis (HP:0011422)2.10257427
124Mildly elevated creatine phosphokinase (HP:0008180)2.09988419
125Mesangial abnormality (HP:0001966)2.09957422
126Growth hormone excess (HP:0000845)2.09350870
127Abnormality of T cell physiology (HP:0011840)2.08572046
128Abnormal foot bone ossification (HP:0010675)2.08202672
129Inflammation of the large intestine (HP:0002037)2.06991922
130Abnormality of potassium homeostasis (HP:0011042)2.05202853
131Pancreatitis (HP:0001733)2.04960698
132Metabolic acidosis (HP:0001942)2.04668574
133Cerebral palsy (HP:0100021)2.03853794
134Fatigue (HP:0012378)2.03130958
135Hyponatremia (HP:0002902)2.02616006
136Glycosuria (HP:0003076)2.02523362
137Abnormality of urine glucose concentration (HP:0011016)2.02523362
138Abnormal hair laboratory examination (HP:0003328)2.02430674
139Enlarged epiphyses (HP:0010580)2.02070931
140Recurrent viral infections (HP:0004429)2.01417263
141Syncope (HP:0001279)1.99264168
142Hypoproteinemia (HP:0003075)1.98554670
143Posterior subcapsular cataract (HP:0007787)1.97642644
144Hyperphosphaturia (HP:0003109)1.94538096
145Abnormal urine phosphate concentration (HP:0012599)1.94112651
146Gastrointestinal inflammation (HP:0004386)1.92478283
147Abnormality of the distal phalanx of the thumb (HP:0009617)1.89803713
148Intrahepatic cholestasis (HP:0001406)1.89696807
149Reticulocytopenia (HP:0001896)1.89263218
150Abnormality of vitamin B metabolism (HP:0004340)1.88652785
151Metabolic alkalosis (HP:0200114)1.87245845
152Renal tubular acidosis (HP:0001947)1.87146811
153Progressive hearing impairment (HP:0001730)1.84797646
154Hoarse voice (HP:0001609)1.84785631
155Megaloblastic anemia (HP:0001889)1.83432255
156Symptomatic seizures (HP:0011145)1.82642418
157Cardiovascular calcification (HP:0011915)1.82259769
158Delayed epiphyseal ossification (HP:0002663)1.81724888
159Irritability (HP:0000737)1.81590547
160Severe combined immunodeficiency (HP:0004430)1.81254015
161Vacuolated lymphocytes (HP:0001922)1.80083175
162Abnormal albumin level (HP:0012116)1.79981786
163Hypoalbuminemia (HP:0003073)1.79981786
164Progressive sensorineural hearing impairment (HP:0000408)1.79448360
165Recurrent fungal infections (HP:0002841)1.79321176
166Abnormality of the nasal mucosa (HP:0000433)1.78548192
167Hyperbilirubinemia (HP:0002904)1.77594780
168Fragile skin (HP:0001030)1.76715074
169Abnormality of carpal bone ossification (HP:0006257)1.74922885

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST1R5.19910292
2FRK4.46978726
3MST43.98865148
4LMTK23.54157723
5PIK3CA3.19992645
6PRKG23.08388232
7NME12.80938998
8MAP2K22.62685596
9STK392.49805081
10MATK2.18329198
11FGFR42.13503669
12TAOK32.12203372
13EEF2K2.11903604
14MAP3K122.03086735
15GRK61.94123037
16STK241.93490209
17TNIK1.89785244
18EPHA31.88680928
19KIT1.81894887
20OXSR11.81826491
21PIM21.80216236
22MYLK1.79007966
23RIPK11.73367429
24EPHA21.71812528
25MAP3K101.60049053
26MAP3K21.57465052
27TESK11.45631627
28PTK61.43267188
29SCYL21.41499365
30RPS6KB21.39401630
31FGFR31.39348174
32TGFBR11.38609847
33ACVR1B1.32613585
34MAP2K61.28059245
35PAK41.25503156
36MAP2K31.22758514
37MAP4K11.20697974
38TEC1.19211813
39FER1.18142981
40CDK191.12036078
41STK161.10119830
42PDK21.09800628
43CDC42BPA1.08280381
44MET1.07252094
45TBK11.06490498
46DDR21.03533564
47ERN11.03206501
48STK101.03017881
49FLT31.00767344
50BTK0.99450296
51MAPKAPK30.95611673
52EPHB20.94585605
53TAOK10.93992035
54MAP3K80.93881854
55TESK20.92375894
56PRPF4B0.89600452
57PDPK10.88266494
58PKN20.86434225
59IRAK10.84716917
60NUAK10.84403131
61MAP3K110.84103930
62WNK40.83472194
63LRRK20.82339904
64RIPK40.80607462
65MAP3K70.79006009
66AURKB0.78967463
67YES10.75452071
68TIE10.73543975
69NLK0.72483872
70PIK3CG0.71019599
71MAPK110.70989701
72CDK70.68131935
73KSR20.68102697
74MUSK0.67686916
75TYK20.66582823
76NME20.66469665
77MAPKAPK50.65880254
78MAP3K60.65316994
79MAP3K10.65302868
80CDK80.65081466
81MAP2K10.64693283
82PRKCI0.61251224
83PDK10.60071706
84PRKAA20.59545722
85ERBB20.58847248
86TTK0.58235231
87IKBKE0.56760104
88BLK0.55441148
89BMPR20.55076686
90JAK10.53745331
91PRKACG0.53432908
92PTK20.52872914
93KDR0.50366949
94PRKCA0.50346258
95BRSK20.50123734
96CASK0.48995899
97PIM10.47200331
98WEE10.46931255
99SRC0.44075140
100MAP3K30.43753267
101PRKCZ0.43419598
102DAPK20.42900647
103JAK30.40879082
104TRPM70.40402751
105VRK10.39262754
106DYRK1B0.38173101
107BMX0.38030230
108BMPR1B0.37043725
109ABL20.35990528
110LYN0.34865384
111AKT30.32728827
112IRAK30.32341911
113CDK90.32120673
114PAK20.31871248
115RAF10.31839825
116EPHA40.31716262
117EPHB10.31405807
118ITK0.31325023
119CSF1R0.30555185
120MAPKAPK20.30120404
121LCK0.30001068
122FYN0.29734298
123ZAP700.29458035
124MAP3K140.28473680
125CAMK2G0.28362926
126DYRK30.28168100
127CAMK2D0.27924883
128CDK60.27837964
129GRK10.27325144
130MAPK40.27249433
131PASK0.26960492
132CSK0.26740338
133JAK20.26393682
134SYK0.25843763
135RET0.25351439
136PRKCD0.23687813
137CSNK1A10.23059269
138PDGFRA0.20954298
139IGF1R0.20382214
140ADRBK20.19645436
141PRKCQ0.18503804
142NEK60.18307771
143PRKCE0.17758175
144PRKD20.14605651
145PHKG10.13095130
146PHKG20.13095130

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005244.59217805
2Fat digestion and absorption_Homo sapiens_hsa049754.27078242
3Mineral absorption_Homo sapiens_hsa049783.89592979
4Renin-angiotensin system_Homo sapiens_hsa046143.61350887
5Caffeine metabolism_Homo sapiens_hsa002323.60974394
6Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006013.53927792
7Sulfur metabolism_Homo sapiens_hsa009203.23142149
8Galactose metabolism_Homo sapiens_hsa000522.94109993
9Arginine biosynthesis_Homo sapiens_hsa002202.81021845
10Vitamin digestion and absorption_Homo sapiens_hsa049772.74795269
11Folate biosynthesis_Homo sapiens_hsa007902.38411306
12Carbohydrate digestion and absorption_Homo sapiens_hsa049732.18607434
13Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.13887911
14Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005202.11667999
15Fructose and mannose metabolism_Homo sapiens_hsa000512.01866833
16Starch and sucrose metabolism_Homo sapiens_hsa005001.99154935
17Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.99135105
18Retinol metabolism_Homo sapiens_hsa008301.94791229
19Bile secretion_Homo sapiens_hsa049761.78146839
20Steroid hormone biosynthesis_Homo sapiens_hsa001401.58591405
21Maturity onset diabetes of the young_Homo sapiens_hsa049501.55727134
22Protein digestion and absorption_Homo sapiens_hsa049741.54080634
23Histidine metabolism_Homo sapiens_hsa003401.49601233
24Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.39247998
25Ribosome_Homo sapiens_hsa030101.34950122
26Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.29681572
27DNA replication_Homo sapiens_hsa030301.29226693
28Thyroid cancer_Homo sapiens_hsa052161.28742079
29Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.24898546
30Glutathione metabolism_Homo sapiens_hsa004801.23551361
31Pentose phosphate pathway_Homo sapiens_hsa000301.17535198
32Pentose and glucuronate interconversions_Homo sapiens_hsa000401.04950539
33Asthma_Homo sapiens_hsa053101.04866241
34N-Glycan biosynthesis_Homo sapiens_hsa005101.03600200
35Nitrogen metabolism_Homo sapiens_hsa009101.03439797
36Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.02240975
37Intestinal immune network for IgA production_Homo sapiens_hsa046721.01202618
38Cyanoamino acid metabolism_Homo sapiens_hsa004600.99236803
39Ether lipid metabolism_Homo sapiens_hsa005650.96883630
40Salmonella infection_Homo sapiens_hsa051320.92492396
41Hematopoietic cell lineage_Homo sapiens_hsa046400.90106845
42Phenylalanine metabolism_Homo sapiens_hsa003600.89080272
43Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.86657895
44Sphingolipid metabolism_Homo sapiens_hsa006000.86130488
45ABC transporters_Homo sapiens_hsa020100.85419864
46Drug metabolism - other enzymes_Homo sapiens_hsa009830.85325058
47Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.85115750
48Type I diabetes mellitus_Homo sapiens_hsa049400.84646275
49RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.82612065
50Staphylococcus aureus infection_Homo sapiens_hsa051500.81997635
51Thyroid hormone synthesis_Homo sapiens_hsa049180.81087769
52Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.79662604
53Glycerolipid metabolism_Homo sapiens_hsa005610.77781482
54Allograft rejection_Homo sapiens_hsa053300.75406164
55Hepatitis C_Homo sapiens_hsa051600.73627023
56Leishmaniasis_Homo sapiens_hsa051400.73239291
57Autoimmune thyroid disease_Homo sapiens_hsa053200.72900853
58Tryptophan metabolism_Homo sapiens_hsa003800.71875229
59Leukocyte transendothelial migration_Homo sapiens_hsa046700.71197422
60Peroxisome_Homo sapiens_hsa041460.70556602
61NOD-like receptor signaling pathway_Homo sapiens_hsa046210.68776844
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.68139429
63Pertussis_Homo sapiens_hsa051330.67269331
64Sulfur relay system_Homo sapiens_hsa041220.66735267
65Pyrimidine metabolism_Homo sapiens_hsa002400.65213433
66Influenza A_Homo sapiens_hsa051640.64423724
67Mismatch repair_Homo sapiens_hsa034300.64380659
68Toxoplasmosis_Homo sapiens_hsa051450.63755794
69African trypanosomiasis_Homo sapiens_hsa051430.63675781
70Graft-versus-host disease_Homo sapiens_hsa053320.63197710
71Fatty acid metabolism_Homo sapiens_hsa012120.59751266
72Legionellosis_Homo sapiens_hsa051340.57276571
73Purine metabolism_Homo sapiens_hsa002300.56386632
74Platelet activation_Homo sapiens_hsa046110.55983568
75PPAR signaling pathway_Homo sapiens_hsa033200.55695684
76Primary immunodeficiency_Homo sapiens_hsa053400.55201326
77Pancreatic secretion_Homo sapiens_hsa049720.54223116
78alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.53038285
79Arachidonic acid metabolism_Homo sapiens_hsa005900.50600221
80Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.50318078
81Complement and coagulation cascades_Homo sapiens_hsa046100.50275578
82Shigellosis_Homo sapiens_hsa051310.49671936
83Fatty acid degradation_Homo sapiens_hsa000710.49564698
84Renin secretion_Homo sapiens_hsa049240.49050563
85Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.48753827
86Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.47630082
87Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.46906777
88Base excision repair_Homo sapiens_hsa034100.46764956
89Other glycan degradation_Homo sapiens_hsa005110.46573277
90Tyrosine metabolism_Homo sapiens_hsa003500.46133744
91Primary bile acid biosynthesis_Homo sapiens_hsa001200.45371238
92Small cell lung cancer_Homo sapiens_hsa052220.44491790
93Acute myeloid leukemia_Homo sapiens_hsa052210.42788948
94Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.41890953
95Butanoate metabolism_Homo sapiens_hsa006500.41682005
96Arginine and proline metabolism_Homo sapiens_hsa003300.41033577
97Herpes simplex infection_Homo sapiens_hsa051680.40696224
98Tight junction_Homo sapiens_hsa045300.40490475
99Carbon metabolism_Homo sapiens_hsa012000.40260251
100Insulin secretion_Homo sapiens_hsa049110.37144292
101Apoptosis_Homo sapiens_hsa042100.35994817
102Insulin resistance_Homo sapiens_hsa049310.35667999
103Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.35233134
104Linoleic acid metabolism_Homo sapiens_hsa005910.34635081
105Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.34244138
106Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.32954110
107Transcriptional misregulation in cancer_Homo sapiens_hsa052020.32823943
108Bladder cancer_Homo sapiens_hsa052190.32635372
109Metabolic pathways_Homo sapiens_hsa011000.32601276
110Selenocompound metabolism_Homo sapiens_hsa004500.32025001
111Fatty acid biosynthesis_Homo sapiens_hsa000610.31726977
112Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.30703073
113Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.30558125
114Vibrio cholerae infection_Homo sapiens_hsa051100.28380715
115Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.28019199
1162-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.28005600
117TNF signaling pathway_Homo sapiens_hsa046680.27699500
118Adipocytokine signaling pathway_Homo sapiens_hsa049200.24725963
119Central carbon metabolism in cancer_Homo sapiens_hsa052300.24656681
120Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.23108827
121Glycerophospholipid metabolism_Homo sapiens_hsa005640.22154061
122Antigen processing and presentation_Homo sapiens_hsa046120.21929086
123Hepatitis B_Homo sapiens_hsa051610.21472794
124beta-Alanine metabolism_Homo sapiens_hsa004100.21301712
125Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.20884591
126Glucagon signaling pathway_Homo sapiens_hsa049220.20715401
127Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.19309927
128B cell receptor signaling pathway_Homo sapiens_hsa046620.19237242
129Propanoate metabolism_Homo sapiens_hsa006400.18640116
130Toll-like receptor signaling pathway_Homo sapiens_hsa046200.18603181
131Chemical carcinogenesis_Homo sapiens_hsa052040.18186655
132Chronic myeloid leukemia_Homo sapiens_hsa052200.17517319
133HIF-1 signaling pathway_Homo sapiens_hsa040660.16781841
134Pyruvate metabolism_Homo sapiens_hsa006200.16511298
135Glycosaminoglycan degradation_Homo sapiens_hsa005310.16010932
136Fatty acid elongation_Homo sapiens_hsa000620.14957848
137Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.12759756
138Cocaine addiction_Homo sapiens_hsa050300.11218786
139Biosynthesis of amino acids_Homo sapiens_hsa012300.10826516
140Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.08387579

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