Rank | Gene Set | Z-score |
---|---|---|
1 | intestinal absorption (GO:0050892) | 8.59523085 |
2 | intestinal cholesterol absorption (GO:0030299) | 7.79201545 |
3 | angiotensin maturation (GO:0002003) | 7.46256328 |
4 | regulation of guanylate cyclase activity (GO:0031282) | 6.71151621 |
5 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 6.44177680 |
6 | NADH metabolic process (GO:0006734) | 5.57587332 |
7 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 5.41995206 |
8 | epoxygenase P450 pathway (GO:0019373) | 5.33657115 |
9 | positive regulation of guanylate cyclase activity (GO:0031284) | 5.00762763 |
10 | L-fucose catabolic process (GO:0042355) | 4.95081636 |
11 | fucose catabolic process (GO:0019317) | 4.95081636 |
12 | L-fucose metabolic process (GO:0042354) | 4.95081636 |
13 | actin filament depolymerization (GO:0030042) | 4.93172401 |
14 | vitamin A metabolic process (GO:0006776) | 4.92171558 |
15 | cellular glucuronidation (GO:0052695) | 4.85312920 |
16 | regulation of cellular extravasation (GO:0002691) | 4.85267536 |
17 | positive regulation of respiratory burst (GO:0060267) | 4.84031463 |
18 | glucuronate metabolic process (GO:0019585) | 4.76910427 |
19 | uronic acid metabolic process (GO:0006063) | 4.76910427 |
20 | thrombin receptor signaling pathway (GO:0070493) | 4.68514328 |
21 | hepatocyte apoptotic process (GO:0097284) | 4.60212256 |
22 | regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044) | 4.58474977 |
23 | endocrine process (GO:0050886) | 4.58474977 |
24 | regulation of systemic arterial blood pressure by hormone (GO:0001990) | 4.58474977 |
25 | fat-soluble vitamin biosynthetic process (GO:0042362) | 4.53710693 |
26 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 4.47973692 |
27 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 4.47973692 |
28 | flavonoid metabolic process (GO:0009812) | 4.47770456 |
29 | urea cycle (GO:0000050) | 4.45710852 |
30 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.43102295 |
31 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.43102295 |
32 | glucose 6-phosphate metabolic process (GO:0051156) | 4.30902158 |
33 | regulation of RIG-I signaling pathway (GO:0039535) | 4.29069900 |
34 | urea metabolic process (GO:0019627) | 4.27093017 |
35 | receptor guanylyl cyclase signaling pathway (GO:0007168) | 4.23983788 |
36 | peptide hormone processing (GO:0016486) | 4.23962233 |
37 | regulation of systemic arterial blood pressure (GO:0003073) | 4.18609990 |
38 | lipoprotein transport (GO:0042953) | 4.17519240 |
39 | regulation of cGMP biosynthetic process (GO:0030826) | 4.12812733 |
40 | hormone catabolic process (GO:0042447) | 4.12809118 |
41 | drug metabolic process (GO:0017144) | 4.11606750 |
42 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 4.11335800 |
43 | diacylglycerol metabolic process (GO:0046339) | 4.04010428 |
44 | sulfate transmembrane transport (GO:1902358) | 4.00886311 |
45 | positive regulation of pseudopodium assembly (GO:0031274) | 3.97599153 |
46 | ribosomal small subunit assembly (GO:0000028) | 3.97339672 |
47 | phospholipid scrambling (GO:0017121) | 3.94655457 |
48 | glomerular filtration (GO:0003094) | 3.92543577 |
49 | nitrogen cycle metabolic process (GO:0071941) | 3.91483193 |
50 | hemidesmosome assembly (GO:0031581) | 3.89753165 |
51 | thyroid hormone metabolic process (GO:0042403) | 3.88045519 |
52 | ethanol oxidation (GO:0006069) | 3.86491309 |
53 | bile acid and bile salt transport (GO:0015721) | 3.85592990 |
54 | * digestive system process (GO:0022600) | 3.84337132 |
55 | fructose metabolic process (GO:0006000) | 3.81387871 |
56 | renal system process involved in regulation of blood volume (GO:0001977) | 3.80148052 |
57 | regulation of vitamin metabolic process (GO:0030656) | 3.77586155 |
58 | arginine metabolic process (GO:0006525) | 3.77091764 |
59 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 3.76113619 |
60 | auditory receptor cell differentiation (GO:0042491) | 3.73458952 |
61 | purine nucleotide salvage (GO:0032261) | 3.65969122 |
62 | intestinal epithelial cell development (GO:0060576) | 3.65733094 |
63 | transcytosis (GO:0045056) | 3.64164600 |
64 | sulfation (GO:0051923) | 3.64002935 |
65 | complement activation, classical pathway (GO:0006958) | 3.63058570 |
66 | regulation of respiratory burst (GO:0060263) | 3.62957999 |
67 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 3.58147981 |
68 | regulation of pseudopodium assembly (GO:0031272) | 3.57963390 |
69 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.57307910 |
70 | renal filtration (GO:0097205) | 3.57148695 |
71 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 3.54726332 |
72 | glycosphingolipid catabolic process (GO:0046479) | 3.53134116 |
73 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.52795025 |
74 | * O-glycan processing (GO:0016266) | 3.52276243 |
75 | glycolipid catabolic process (GO:0019377) | 3.51470964 |
76 | hydrogen peroxide catabolic process (GO:0042744) | 3.50204690 |
77 | response to hepatocyte growth factor (GO:0035728) | 3.46742546 |
78 | cellular response to hepatocyte growth factor stimulus (GO:0035729) | 3.46742546 |
79 | drug catabolic process (GO:0042737) | 3.46372165 |
80 | nucleotide-sugar metabolic process (GO:0009225) | 3.45607179 |
81 | vitamin transmembrane transport (GO:0035461) | 3.42463511 |
82 | regulation of cholesterol homeostasis (GO:2000188) | 3.41117793 |
83 | antimicrobial humoral response (GO:0019730) | 3.40034510 |
84 | antibacterial humoral response (GO:0019731) | 3.39367222 |
85 | regulation of cGMP metabolic process (GO:0030823) | 3.37193285 |
86 | oligosaccharide biosynthetic process (GO:0009312) | 3.34094590 |
87 | adhesion of symbiont to host cell (GO:0044650) | 3.32126209 |
88 | virion attachment to host cell (GO:0019062) | 3.32126209 |
89 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.31087452 |
90 | regulation of viral entry into host cell (GO:0046596) | 3.26262441 |
91 | regulation of bile acid biosynthetic process (GO:0070857) | 3.24367168 |
92 | sulfate transport (GO:0008272) | 3.24094571 |
93 | sulfur compound transport (GO:0072348) | 3.22829645 |
94 | regulation of actin nucleation (GO:0051125) | 3.22159708 |
95 | definitive hemopoiesis (GO:0060216) | 3.21555981 |
96 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 3.21130031 |
97 | regulation of viral release from host cell (GO:1902186) | 3.21099937 |
98 | digestion (GO:0007586) | 3.19976975 |
99 | positive regulation of glycoprotein metabolic process (GO:1903020) | 3.19805578 |
100 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.18809292 |
101 | fucose metabolic process (GO:0006004) | 3.18782828 |
102 | galactose catabolic process (GO:0019388) | 3.18665325 |
103 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.16547478 |
104 | actin nucleation (GO:0045010) | 3.16314152 |
105 | GDP-mannose metabolic process (GO:0019673) | 3.14907688 |
106 | eosinophil chemotaxis (GO:0048245) | 3.14531817 |
107 | mature B cell differentiation involved in immune response (GO:0002313) | 3.14227659 |
108 | nucleoside diphosphate biosynthetic process (GO:0009133) | 3.13648186 |
109 | striated muscle atrophy (GO:0014891) | 3.13092755 |
110 | sperm capacitation (GO:0048240) | 3.12852799 |
111 | ethanol metabolic process (GO:0006067) | 3.12840756 |
112 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 3.12409929 |
113 | regulation of extracellular matrix disassembly (GO:0010715) | 3.12172197 |
114 | vitamin transport (GO:0051180) | 3.11698745 |
115 | phospholipid efflux (GO:0033700) | 3.11101998 |
116 | glutamine family amino acid biosynthetic process (GO:0009084) | 3.10748850 |
117 | glycosylceramide metabolic process (GO:0006677) | 3.05623876 |
118 | modified amino acid transport (GO:0072337) | 3.05293773 |
119 | drug transmembrane transport (GO:0006855) | 3.03714975 |
120 | alkaloid metabolic process (GO:0009820) | 3.02016125 |
121 | negative regulation of viral entry into host cell (GO:0046597) | 3.01951668 |
122 | plasma lipoprotein particle assembly (GO:0034377) | 3.01828926 |
123 | exogenous drug catabolic process (GO:0042738) | 2.99348464 |
124 | bile acid metabolic process (GO:0008206) | 2.98696746 |
125 | sphingolipid catabolic process (GO:0030149) | 2.98359607 |
126 | cGMP-mediated signaling (GO:0019934) | 2.95915243 |
127 | drug transport (GO:0015893) | 2.95492334 |
128 | hexose catabolic process (GO:0019320) | 2.94907187 |
129 | positive regulation of cGMP biosynthetic process (GO:0030828) | 2.94334047 |
130 | positive regulation of lipid catabolic process (GO:0050996) | 2.92485798 |
131 | arginine catabolic process (GO:0006527) | 2.91595735 |
132 | ceramide catabolic process (GO:0046514) | 2.90650288 |
133 | complement activation (GO:0006956) | 2.90016820 |
134 | nucleotide salvage (GO:0043173) | 2.87167959 |
135 | regulation of triglyceride catabolic process (GO:0010896) | 2.86295772 |
136 | viral transcription (GO:0019083) | 2.84930734 |
137 | phenylpropanoid metabolic process (GO:0009698) | 2.84859312 |
138 | regulation of membrane lipid distribution (GO:0097035) | 2.84321437 |
139 | hydrogen peroxide metabolic process (GO:0042743) | 2.82210863 |
140 | nucleotide-sugar biosynthetic process (GO:0009226) | 2.81689948 |
141 | histamine transport (GO:0051608) | 2.81223309 |
142 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.81128136 |
143 | protein-lipid complex assembly (GO:0065005) | 2.80538224 |
144 | membrane lipid catabolic process (GO:0046466) | 2.79752975 |
145 | midgut development (GO:0007494) | 2.79128530 |
146 | renal system process involved in regulation of systemic arterial blood pressure (GO:0003071) | 2.78930327 |
147 | peptide catabolic process (GO:0043171) | 2.76379016 |
148 | detection of bacterium (GO:0016045) | 2.76351966 |
149 | positive regulation of glycoprotein biosynthetic process (GO:0010560) | 2.75368070 |
150 | * maintenance of gastrointestinal epithelium (GO:0030277) | 2.75118782 |
151 | lipoprotein metabolic process (GO:0042157) | 2.74652322 |
152 | muscle atrophy (GO:0014889) | 2.73302779 |
153 | response to hydroperoxide (GO:0033194) | 2.72454419 |
154 | sphingomyelin metabolic process (GO:0006684) | 2.71417876 |
155 | positive regulation of lipoprotein lipase activity (GO:0051006) | 2.69972173 |
156 | positive regulation of triglyceride lipase activity (GO:0061365) | 2.69972173 |
157 | translational termination (GO:0006415) | 2.69676412 |
158 | regulation of proton transport (GO:0010155) | 2.69289564 |
159 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 2.67787247 |
160 | adhesion of symbiont to host (GO:0044406) | 2.64956978 |
161 | innate immune response in mucosa (GO:0002227) | 2.64762835 |
162 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.64631235 |
163 | lipopolysaccharide biosynthetic process (GO:0009103) | 2.63665678 |
164 | execution phase of apoptosis (GO:0097194) | 2.62452300 |
165 | skeletal muscle adaptation (GO:0043501) | 2.62193259 |
166 | Peyers patch development (GO:0048541) | 2.60202244 |
167 | mucosal-associated lymphoid tissue development (GO:0048537) | 2.60202244 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 6.10963424 |
2 | * CDX2_20551321_ChIP-Seq_CACO-2_Human | 4.36531350 |
3 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.14702942 |
4 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 3.02080729 |
5 | GATA1_22025678_ChIP-Seq_K562_Human | 2.88835124 |
6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.82691240 |
7 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.76733677 |
8 | * HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 2.65508518 |
9 | * GATA4_25053715_ChIP-Seq_YYC3_Human | 2.58226682 |
10 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.57670791 |
11 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.54523229 |
12 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.49734531 |
13 | * GATA6_25053715_ChIP-Seq_YYC3_Human | 2.44454381 |
14 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.41877363 |
15 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.37091917 |
16 | * SOX2_20726797_ChIP-Seq_SW620_Human | 2.23026510 |
17 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 2.22979945 |
18 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.20898090 |
19 | * MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.19230842 |
20 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 2.13995525 |
21 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.12068085 |
22 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.12020753 |
23 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 2.09699009 |
24 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.07736046 |
25 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 2.03817051 |
26 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 2.03724265 |
27 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.91757558 |
28 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.91590286 |
29 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.88477117 |
30 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.87869184 |
31 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.84734778 |
32 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.81203581 |
33 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.79987020 |
34 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.79124174 |
35 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.77026926 |
36 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.75771771 |
37 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.70719571 |
38 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.67636774 |
39 | * GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.64533058 |
40 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.64381520 |
41 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.63132220 |
42 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.59016873 |
43 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.56878621 |
44 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.55866939 |
45 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.55357503 |
46 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.54307684 |
47 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.49955523 |
48 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.48543497 |
49 | * GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.47741567 |
50 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 1.46650407 |
51 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.45835678 |
52 | GATA2_19941826_ChIP-Seq_K562_Human | 1.44816070 |
53 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.43042160 |
54 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.42768549 |
55 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.41364294 |
56 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.40429027 |
57 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.39670330 |
58 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.37997982 |
59 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.37414849 |
60 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.34711834 |
61 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.33663887 |
62 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.32965848 |
63 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.31291440 |
64 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.31089179 |
65 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.30741218 |
66 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.29388953 |
67 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.29199152 |
68 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29025383 |
69 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.28526006 |
70 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.28318597 |
71 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.28206462 |
72 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.24119920 |
73 | ATF3_27146783_Chip-Seq_COLON_Human | 1.22515986 |
74 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.22435283 |
75 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.21377548 |
76 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.21315632 |
77 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.20766667 |
78 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.19871584 |
79 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.19560553 |
80 | MYB_26560356_Chip-Seq_TH2_Human | 1.19364559 |
81 | MAF_26560356_Chip-Seq_TH1_Human | 1.19199307 |
82 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.18834947 |
83 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.17911401 |
84 | UTX_26944678_Chip-Seq_JUKART_Human | 1.17175392 |
85 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.17166721 |
86 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.17086116 |
87 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.16348519 |
88 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.15884745 |
89 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.15217869 |
90 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.13957102 |
91 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.13650686 |
92 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.13489583 |
93 | * KLF5_25053715_ChIP-Seq_YYC3_Human | 1.13397106 |
94 | SPI1_23127762_ChIP-Seq_K562_Human | 1.12988063 |
95 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.12979733 |
96 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.11947458 |
97 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.10263255 |
98 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.10247046 |
99 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.09647343 |
100 | MYB_26560356_Chip-Seq_TH1_Human | 1.09497681 |
101 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.09309339 |
102 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.08893183 |
103 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.08785429 |
104 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.07126875 |
105 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.06822808 |
106 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.06343692 |
107 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.04625441 |
108 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.04613744 |
109 | * EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.04559693 |
110 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.04208676 |
111 | MYC_22102868_ChIP-Seq_BL_Human | 1.03085366 |
112 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.02618381 |
113 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.02130042 |
114 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.01870183 |
115 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.01870183 |
116 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.01734486 |
117 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.00198052 |
118 | GATA1_19941826_ChIP-Seq_K562_Human | 0.99867170 |
119 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.98007918 |
120 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.97225129 |
121 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.97056750 |
122 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.97020878 |
123 | JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 0.96313991 |
124 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.96036769 |
125 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.95260146 |
126 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.94930927 |
127 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.94580750 |
128 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.92819812 |
129 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.92255918 |
130 | SA1_27219007_Chip-Seq_Bcells_Human | 0.90990706 |
131 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.90926469 |
132 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.90749987 |
133 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.90585077 |
134 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.89706983 |
135 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 0.88931918 |
136 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.87161527 |
137 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.86957804 |
138 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.86916238 |
139 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.85923947 |
140 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.85183620 |
141 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.84832326 |
142 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.82332578 |
143 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.82198120 |
144 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.80933671 |
145 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.80785331 |
146 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.80321980 |
147 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.79989364 |
148 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.77761299 |
149 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.76981611 |
150 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.76321222 |
151 | * PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.73874221 |
152 | * TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 0.73555822 |
153 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.72750294 |
154 | FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.71734110 |
155 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.69203411 |
156 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.68709115 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005360_urolithiasis | 5.41983182 |
2 | MP0010234_abnormal_vibrissa_follicle | 4.99667028 |
3 | MP0001666_abnormal_nutrient_absorption | 4.46173365 |
4 | MP0003866_abnormal_defecation | 4.09798151 |
5 | MP0004264_abnormal_extraembryonic_tissu | 4.00015880 |
6 | MP0001873_stomach_inflammation | 3.21738887 |
7 | MP0004147_increased_porphyrin_level | 3.10108494 |
8 | MP0010155_abnormal_intestine_physiology | 3.01657395 |
9 | MP0000490_abnormal_crypts_of | 2.98982036 |
10 | MP0000462_abnormal_digestive_system | 2.75010488 |
11 | MP0001663_abnormal_digestive_system | 2.61481943 |
12 | MP0006054_spinal_hemorrhage | 2.41507216 |
13 | MP0005085_abnormal_gallbladder_physiolo | 2.39241475 |
14 | MP0005381_digestive/alimentary_phenotyp | 2.28157116 |
15 | MP0010352_gastrointestinal_tract_polyps | 2.27141104 |
16 | MP0003183_abnormal_peptide_metabolism | 2.21062519 |
17 | MP0000477_abnormal_intestine_morphology | 2.11346091 |
18 | MP0009379_abnormal_foot_pigmentation | 2.05151388 |
19 | MP0008875_abnormal_xenobiotic_pharmacok | 2.04496680 |
20 | MP0002138_abnormal_hepatobiliary_system | 2.03761095 |
21 | MP0009840_abnormal_foam_cell | 1.98117128 |
22 | MP0002396_abnormal_hematopoietic_system | 1.93553541 |
23 | MP0005332_abnormal_amino_acid | 1.91891605 |
24 | MP0003252_abnormal_bile_duct | 1.86589653 |
25 | MP0000465_gastrointestinal_hemorrhage | 1.85644150 |
26 | MP0002822_catalepsy | 1.85058656 |
27 | MP0001664_abnormal_digestion | 1.80077293 |
28 | MP0005409_darkened_coat_color | 1.79618249 |
29 | MP0002139_abnormal_hepatobiliary_system | 1.70502586 |
30 | MP0003300_gastrointestinal_ulcer | 1.68412592 |
31 | MP0009785_altered_susceptibility_to | 1.66105040 |
32 | MP0005464_abnormal_platelet_physiology | 1.65594089 |
33 | MP0004782_abnormal_surfactant_physiolog | 1.62672805 |
34 | MP0005377_hearing/vestibular/ear_phenot | 1.61190112 |
35 | MP0003878_abnormal_ear_physiology | 1.61190112 |
36 | MP0000537_abnormal_urethra_morphology | 1.59279552 |
37 | MP0010329_abnormal_lipoprotein_level | 1.58104764 |
38 | MP0005174_abnormal_tail_pigmentation | 1.57607723 |
39 | MP0003693_abnormal_embryo_hatching | 1.51027993 |
40 | MP0005365_abnormal_bile_salt | 1.47284741 |
41 | MP0004858_abnormal_nervous_system | 1.41412079 |
42 | MP0004947_skin_inflammation | 1.33887830 |
43 | MP0001756_abnormal_urination | 1.33276678 |
44 | MP0005025_abnormal_response_to | 1.29290980 |
45 | MP0003724_increased_susceptibility_to | 1.29144669 |
46 | MP0003879_abnormal_hair_cell | 1.27351886 |
47 | MP0000678_abnormal_parathyroid_gland | 1.26583632 |
48 | MP0005397_hematopoietic_system_phenotyp | 1.24446200 |
49 | MP0001545_abnormal_hematopoietic_system | 1.24446200 |
50 | MP0002136_abnormal_kidney_physiology | 1.24412678 |
51 | MP0002876_abnormal_thyroid_physiology | 1.23161195 |
52 | MP0005084_abnormal_gallbladder_morpholo | 1.22608867 |
53 | MP0002118_abnormal_lipid_homeostasis | 1.21868546 |
54 | MP0001849_ear_inflammation | 1.16511130 |
55 | MP0003191_abnormal_cellular_cholesterol | 1.16449054 |
56 | MP0000538_abnormal_urinary_bladder | 1.16222619 |
57 | MP0010678_abnormal_skin_adnexa | 1.15997175 |
58 | MP0001835_abnormal_antigen_presentation | 1.10699948 |
59 | MP0002166_altered_tumor_susceptibility | 1.07533294 |
60 | MP0005671_abnormal_response_to | 1.06108743 |
61 | MP0005167_abnormal_blood-brain_barrier | 1.04936362 |
62 | MP0002148_abnormal_hypersensitivity_rea | 1.03642445 |
63 | MP0003868_abnormal_feces_composition | 1.02905580 |
64 | MP0005058_abnormal_lysosome_morphology | 1.02746705 |
65 | MP0008872_abnormal_physiological_respon | 1.02011597 |
66 | MP0001501_abnormal_sleep_pattern | 1.01902436 |
67 | MP0005670_abnormal_white_adipose | 1.01896622 |
68 | MP0005166_decreased_susceptibility_to | 1.01446373 |
69 | MP0005451_abnormal_body_composition | 0.98189258 |
70 | MP0001845_abnormal_inflammatory_respons | 0.97762526 |
71 | MP0004270_analgesia | 0.97600397 |
72 | MP0009333_abnormal_splenocyte_physiolog | 0.97578715 |
73 | MP0001765_abnormal_ion_homeostasis | 0.96800561 |
74 | MP0003806_abnormal_nucleotide_metabolis | 0.96244062 |
75 | MP0004043_abnormal_pH_regulation | 0.95648567 |
76 | MP0001819_abnormal_immune_cell | 0.94477230 |
77 | MP0009643_abnormal_urine_homeostasis | 0.93642692 |
78 | MP0005310_abnormal_salivary_gland | 0.93636882 |
79 | MP0002796_impaired_skin_barrier | 0.93452087 |
80 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.91731982 |
81 | MP0004019_abnormal_vitamin_homeostasis | 0.91711369 |
82 | MP0003436_decreased_susceptibility_to | 0.91124910 |
83 | MP0002089_abnormal_postnatal_growth/wei | 0.90967960 |
84 | MP0002971_abnormal_brown_adipose | 0.90861880 |
85 | MP0002452_abnormal_antigen_presenting | 0.90084165 |
86 | MP0000230_abnormal_systemic_arterial | 0.90007935 |
87 | MP0002420_abnormal_adaptive_immunity | 0.90004273 |
88 | MP0004808_abnormal_hematopoietic_stem | 0.89064073 |
89 | MP0000013_abnormal_adipose_tissue | 0.87115333 |
90 | MP0004957_abnormal_blastocyst_morpholog | 0.85976831 |
91 | MP0003329_amyloid_beta_deposits | 0.85315864 |
92 | MP0005501_abnormal_skin_physiology | 0.84773471 |
93 | MP0002006_tumorigenesis | 0.84595633 |
94 | MP0005636_abnormal_mineral_homeostasis | 0.83337585 |
95 | MP0002398_abnormal_bone_marrow | 0.82832033 |
96 | MP0001800_abnormal_humoral_immune | 0.82016657 |
97 | MP0008873_increased_physiological_sensi | 0.81777979 |
98 | MP0000467_abnormal_esophagus_morphology | 0.81665206 |
99 | MP0002132_abnormal_respiratory_system | 0.80811461 |
100 | MP0000470_abnormal_stomach_morphology | 0.80723126 |
101 | MP0002909_abnormal_adrenal_gland | 0.80679461 |
102 | MP0005535_abnormal_body_temperature | 0.79546677 |
103 | MP0003315_abnormal_perineum_morphology | 0.79156685 |
104 | MP0002723_abnormal_immune_serum | 0.75697477 |
105 | MP0005319_abnormal_enzyme/_coenzyme | 0.75543667 |
106 | MP0009780_abnormal_chondrocyte_physiolo | 0.75530421 |
107 | MP0003763_abnormal_thymus_physiology | 0.75433283 |
108 | MP0009697_abnormal_copulation | 0.75320126 |
109 | MP0002429_abnormal_blood_cell | 0.75238079 |
110 | MP0002419_abnormal_innate_immunity | 0.75220619 |
111 | MP0001216_abnormal_epidermal_layer | 0.74797667 |
112 | MP0002896_abnormal_bone_mineralization | 0.74576498 |
113 | MP0001188_hyperpigmentation | 0.73804662 |
114 | MP0006082_CNS_inflammation | 0.73735802 |
115 | MP0000609_abnormal_liver_physiology | 0.72827619 |
116 | MP0000685_abnormal_immune_system | 0.72776342 |
117 | MP0000604_amyloidosis | 0.72660320 |
118 | MP0009642_abnormal_blood_homeostasis | 0.72656456 |
119 | MP0002078_abnormal_glucose_homeostasis | 0.72474328 |
120 | MP0008469_abnormal_protein_level | 0.72395039 |
121 | MP0000716_abnormal_immune_system | 0.72176873 |
122 | MP0010307_abnormal_tumor_latency | 0.72161069 |
123 | MP0001764_abnormal_homeostasis | 0.70973108 |
124 | MP0003705_abnormal_hypodermis_morpholog | 0.69601198 |
125 | MP0002722_abnormal_immune_system | 0.69189103 |
126 | MP0005448_abnormal_energy_balance | 0.69147759 |
127 | MP0003303_peritoneal_inflammation | 0.68923605 |
128 | MP0005165_increased_susceptibility_to | 0.68430700 |
129 | MP0001485_abnormal_pinna_reflex | 0.68427436 |
130 | MP0002098_abnormal_vibrissa_morphology | 0.67068772 |
131 | MP0001790_abnormal_immune_system | 0.66928654 |
132 | MP0005387_immune_system_phenotype | 0.66928654 |
133 | MP0003953_abnormal_hormone_level | 0.66820493 |
134 | MP0009115_abnormal_fat_cell | 0.65724726 |
135 | MP0003453_abnormal_keratinocyte_physiol | 0.64646708 |
136 | MP0003283_abnormal_digestive_organ | 0.58013434 |
137 | MP0008004_abnormal_stomach_pH | 0.56815015 |
138 | MP0001881_abnormal_mammary_gland | 0.56149091 |
139 | MP0000566_synostosis | 0.54721214 |
140 | MP0003045_fibrosis | 0.54244858 |
141 | MP0003075_altered_response_to | 0.53862554 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ileus (HP:0002595) | 6.54254203 |
2 | Right ventricular cardiomyopathy (HP:0011663) | 5.06678204 |
3 | Acanthocytosis (HP:0001927) | 4.90767981 |
4 | Decreased circulating renin level (HP:0003351) | 4.59425615 |
5 | Petechiae (HP:0000967) | 4.53829121 |
6 | Systemic lupus erythematosus (HP:0002725) | 4.24216785 |
7 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 4.17311880 |
8 | Chronic diarrhea (HP:0002028) | 4.06056626 |
9 | Abnormality of renin-angiotensin system (HP:0000847) | 4.00881806 |
10 | Malnutrition (HP:0004395) | 3.96097391 |
11 | Alkalosis (HP:0001948) | 3.93530597 |
12 | Pustule (HP:0200039) | 3.90896363 |
13 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 3.83618249 |
14 | Conjugated hyperbilirubinemia (HP:0002908) | 3.74562536 |
15 | Autoimmune thrombocytopenia (HP:0001973) | 3.71374856 |
16 | Abnormality of vitamin metabolism (HP:0100508) | 3.66052930 |
17 | Onycholysis (HP:0001806) | 3.64120527 |
18 | Abnormality of small intestinal villus morphology (HP:0011472) | 3.58189344 |
19 | Villous atrophy (HP:0011473) | 3.58189344 |
20 | Abdominal distention (HP:0003270) | 3.55662409 |
21 | Milia (HP:0001056) | 3.52585363 |
22 | Hypobetalipoproteinemia (HP:0003563) | 3.49466827 |
23 | Thrombocytosis (HP:0001894) | 3.49083024 |
24 | Congenital sensorineural hearing impairment (HP:0008527) | 3.45534880 |
25 | Widely patent fontanelles and sutures (HP:0004492) | 3.44872368 |
26 | Flat acetabular roof (HP:0003180) | 3.34036726 |
27 | Autoimmune hemolytic anemia (HP:0001890) | 3.32051519 |
28 | Reduced antithrombin III activity (HP:0001976) | 3.23674413 |
29 | Poikilocytosis (HP:0004447) | 3.05909692 |
30 | Abnormal platelet function (HP:0011869) | 3.01967328 |
31 | Impaired platelet aggregation (HP:0003540) | 3.01967328 |
32 | Proximal tubulopathy (HP:0000114) | 3.00832400 |
33 | Hyperactive renin-angiotensin system (HP:0000841) | 2.97282701 |
34 | Cupped ribs (HP:0000887) | 2.95407912 |
35 | Glomerulonephritis (HP:0000099) | 2.94842664 |
36 | Aplastic anemia (HP:0001915) | 2.94049510 |
37 | Xanthomatosis (HP:0000991) | 2.93125396 |
38 | Woolly hair (HP:0002224) | 2.90112068 |
39 | Confusion (HP:0001289) | 2.89762028 |
40 | Hydroxyprolinuria (HP:0003080) | 2.87402129 |
41 | Abnormality of proline metabolism (HP:0010907) | 2.87402129 |
42 | Hemorrhage of the eye (HP:0011885) | 2.87103520 |
43 | Microretrognathia (HP:0000308) | 2.84928307 |
44 | Thin bony cortex (HP:0002753) | 2.82529636 |
45 | Fragile nails (HP:0001808) | 2.81506049 |
46 | Fat malabsorption (HP:0002630) | 2.81391286 |
47 | Dehydration (HP:0001944) | 2.80058538 |
48 | Palpitations (HP:0001962) | 2.79256017 |
49 | Pili torti (HP:0003777) | 2.79049081 |
50 | Increased mean platelet volume (HP:0011877) | 2.77836777 |
51 | Abnormal platelet volume (HP:0011876) | 2.74535007 |
52 | Chronic otitis media (HP:0000389) | 2.71448806 |
53 | Hyperammonemia (HP:0001987) | 2.71116191 |
54 | Hypotension (HP:0002615) | 2.67492260 |
55 | Gout (HP:0001997) | 2.64170259 |
56 | Gastrointestinal dysmotility (HP:0002579) | 2.63957888 |
57 | Increased purine levels (HP:0004368) | 2.63009613 |
58 | Hyperuricemia (HP:0002149) | 2.63009613 |
59 | Focal segmental glomerulosclerosis (HP:0000097) | 2.60891646 |
60 | Ureteral stenosis (HP:0000071) | 2.60422724 |
61 | Prostate neoplasm (HP:0100787) | 2.59935294 |
62 | Complement deficiency (HP:0004431) | 2.58099412 |
63 | Hyperaldosteronism (HP:0000859) | 2.57529147 |
64 | Increased IgE level (HP:0003212) | 2.56358363 |
65 | Hyperphosphatemia (HP:0002905) | 2.53977887 |
66 | Hyperglycinuria (HP:0003108) | 2.53317121 |
67 | Abnormality of complement system (HP:0005339) | 2.52358840 |
68 | Nausea (HP:0002018) | 2.51791786 |
69 | Micronodular cirrhosis (HP:0001413) | 2.50710106 |
70 | Steatorrhea (HP:0002570) | 2.48582015 |
71 | Nephrolithiasis (HP:0000787) | 2.47739293 |
72 | Abnormal biliary tract morphology (HP:0012440) | 2.46736464 |
73 | Hyperparathyroidism (HP:0000843) | 2.46586551 |
74 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.44543385 |
75 | Atrophic scars (HP:0001075) | 2.44201970 |
76 | Eczematoid dermatitis (HP:0000976) | 2.44109252 |
77 | Wide cranial sutures (HP:0010537) | 2.43139743 |
78 | Abnormal number of erythroid precursors (HP:0012131) | 2.42464768 |
79 | Goiter (HP:0000853) | 2.42033333 |
80 | Late onset (HP:0003584) | 2.41643675 |
81 | Hypophosphatemia (HP:0002148) | 2.38881164 |
82 | Abnormal tarsal ossification (HP:0008369) | 2.38561976 |
83 | Ureteral obstruction (HP:0006000) | 2.38004443 |
84 | IgM deficiency (HP:0002850) | 2.34805023 |
85 | Nephritis (HP:0000123) | 2.33656323 |
86 | B lymphocytopenia (HP:0010976) | 2.30599740 |
87 | Abnormality of B cell number (HP:0010975) | 2.30599740 |
88 | Rectal prolapse (HP:0002035) | 2.30580134 |
89 | Protuberant abdomen (HP:0001538) | 2.29442066 |
90 | Abnormality of the gastric mucosa (HP:0004295) | 2.28654924 |
91 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.28393575 |
92 | Abnormality of glycine metabolism (HP:0010895) | 2.28393575 |
93 | Biliary tract neoplasm (HP:0100574) | 2.26922073 |
94 | Prolonged bleeding time (HP:0003010) | 2.25201521 |
95 | Neoplasm of the rectum (HP:0100743) | 2.23836418 |
96 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.22457544 |
97 | Cheilitis (HP:0100825) | 2.22206360 |
98 | Abnormal protein glycosylation (HP:0012346) | 2.21993131 |
99 | Abnormal glycosylation (HP:0012345) | 2.21993131 |
100 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.21993131 |
101 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.21993131 |
102 | Hypokalemia (HP:0002900) | 2.21360035 |
103 | Abnormality of purine metabolism (HP:0004352) | 2.20927962 |
104 | Type I transferrin isoform profile (HP:0003642) | 2.20614439 |
105 | Neoplasm of the small intestine (HP:0100833) | 2.19794713 |
106 | Pigmentary retinal degeneration (HP:0001146) | 2.19776763 |
107 | Abnormality of the 1st metacarpal (HP:0010009) | 2.19509915 |
108 | Abnormality of nucleobase metabolism (HP:0010932) | 2.17868810 |
109 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.16751464 |
110 | Dicarboxylic aciduria (HP:0003215) | 2.16751464 |
111 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.16598898 |
112 | Plantar hyperkeratosis (HP:0007556) | 2.16351380 |
113 | Potter facies (HP:0002009) | 2.16214023 |
114 | Facial shape deformation (HP:0011334) | 2.16214023 |
115 | Poikiloderma (HP:0001029) | 2.15880323 |
116 | Abnormal glucose tolerance (HP:0001952) | 2.15688922 |
117 | Abnormality of the prostate (HP:0008775) | 2.14335234 |
118 | Glomerulosclerosis (HP:0000096) | 2.14295132 |
119 | Hypolipoproteinemia (HP:0010981) | 2.12366051 |
120 | Vascular calcification (HP:0004934) | 2.11481456 |
121 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.11194295 |
122 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.10772215 |
123 | Abnormality of chloride homeostasis (HP:0011422) | 2.10257427 |
124 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.09988419 |
125 | Mesangial abnormality (HP:0001966) | 2.09957422 |
126 | Growth hormone excess (HP:0000845) | 2.09350870 |
127 | Abnormality of T cell physiology (HP:0011840) | 2.08572046 |
128 | Abnormal foot bone ossification (HP:0010675) | 2.08202672 |
129 | Inflammation of the large intestine (HP:0002037) | 2.06991922 |
130 | Abnormality of potassium homeostasis (HP:0011042) | 2.05202853 |
131 | Pancreatitis (HP:0001733) | 2.04960698 |
132 | Metabolic acidosis (HP:0001942) | 2.04668574 |
133 | Cerebral palsy (HP:0100021) | 2.03853794 |
134 | Fatigue (HP:0012378) | 2.03130958 |
135 | Hyponatremia (HP:0002902) | 2.02616006 |
136 | Glycosuria (HP:0003076) | 2.02523362 |
137 | Abnormality of urine glucose concentration (HP:0011016) | 2.02523362 |
138 | Abnormal hair laboratory examination (HP:0003328) | 2.02430674 |
139 | Enlarged epiphyses (HP:0010580) | 2.02070931 |
140 | Recurrent viral infections (HP:0004429) | 2.01417263 |
141 | Syncope (HP:0001279) | 1.99264168 |
142 | Hypoproteinemia (HP:0003075) | 1.98554670 |
143 | Posterior subcapsular cataract (HP:0007787) | 1.97642644 |
144 | Hyperphosphaturia (HP:0003109) | 1.94538096 |
145 | Abnormal urine phosphate concentration (HP:0012599) | 1.94112651 |
146 | Gastrointestinal inflammation (HP:0004386) | 1.92478283 |
147 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.89803713 |
148 | Intrahepatic cholestasis (HP:0001406) | 1.89696807 |
149 | Reticulocytopenia (HP:0001896) | 1.89263218 |
150 | Abnormality of vitamin B metabolism (HP:0004340) | 1.88652785 |
151 | Metabolic alkalosis (HP:0200114) | 1.87245845 |
152 | Renal tubular acidosis (HP:0001947) | 1.87146811 |
153 | Progressive hearing impairment (HP:0001730) | 1.84797646 |
154 | Hoarse voice (HP:0001609) | 1.84785631 |
155 | Megaloblastic anemia (HP:0001889) | 1.83432255 |
156 | Symptomatic seizures (HP:0011145) | 1.82642418 |
157 | Cardiovascular calcification (HP:0011915) | 1.82259769 |
158 | Delayed epiphyseal ossification (HP:0002663) | 1.81724888 |
159 | Irritability (HP:0000737) | 1.81590547 |
160 | Severe combined immunodeficiency (HP:0004430) | 1.81254015 |
161 | Vacuolated lymphocytes (HP:0001922) | 1.80083175 |
162 | Abnormal albumin level (HP:0012116) | 1.79981786 |
163 | Hypoalbuminemia (HP:0003073) | 1.79981786 |
164 | Progressive sensorineural hearing impairment (HP:0000408) | 1.79448360 |
165 | Recurrent fungal infections (HP:0002841) | 1.79321176 |
166 | Abnormality of the nasal mucosa (HP:0000433) | 1.78548192 |
167 | Hyperbilirubinemia (HP:0002904) | 1.77594780 |
168 | Fragile skin (HP:0001030) | 1.76715074 |
169 | Abnormality of carpal bone ossification (HP:0006257) | 1.74922885 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MST1R | 5.19910292 |
2 | FRK | 4.46978726 |
3 | MST4 | 3.98865148 |
4 | LMTK2 | 3.54157723 |
5 | PIK3CA | 3.19992645 |
6 | PRKG2 | 3.08388232 |
7 | NME1 | 2.80938998 |
8 | MAP2K2 | 2.62685596 |
9 | STK39 | 2.49805081 |
10 | MATK | 2.18329198 |
11 | FGFR4 | 2.13503669 |
12 | TAOK3 | 2.12203372 |
13 | EEF2K | 2.11903604 |
14 | MAP3K12 | 2.03086735 |
15 | GRK6 | 1.94123037 |
16 | STK24 | 1.93490209 |
17 | TNIK | 1.89785244 |
18 | EPHA3 | 1.88680928 |
19 | KIT | 1.81894887 |
20 | OXSR1 | 1.81826491 |
21 | PIM2 | 1.80216236 |
22 | MYLK | 1.79007966 |
23 | RIPK1 | 1.73367429 |
24 | EPHA2 | 1.71812528 |
25 | MAP3K10 | 1.60049053 |
26 | MAP3K2 | 1.57465052 |
27 | TESK1 | 1.45631627 |
28 | PTK6 | 1.43267188 |
29 | SCYL2 | 1.41499365 |
30 | RPS6KB2 | 1.39401630 |
31 | FGFR3 | 1.39348174 |
32 | TGFBR1 | 1.38609847 |
33 | ACVR1B | 1.32613585 |
34 | MAP2K6 | 1.28059245 |
35 | PAK4 | 1.25503156 |
36 | MAP2K3 | 1.22758514 |
37 | MAP4K1 | 1.20697974 |
38 | TEC | 1.19211813 |
39 | FER | 1.18142981 |
40 | CDK19 | 1.12036078 |
41 | STK16 | 1.10119830 |
42 | PDK2 | 1.09800628 |
43 | CDC42BPA | 1.08280381 |
44 | MET | 1.07252094 |
45 | TBK1 | 1.06490498 |
46 | DDR2 | 1.03533564 |
47 | ERN1 | 1.03206501 |
48 | STK10 | 1.03017881 |
49 | FLT3 | 1.00767344 |
50 | BTK | 0.99450296 |
51 | MAPKAPK3 | 0.95611673 |
52 | EPHB2 | 0.94585605 |
53 | TAOK1 | 0.93992035 |
54 | MAP3K8 | 0.93881854 |
55 | TESK2 | 0.92375894 |
56 | PRPF4B | 0.89600452 |
57 | PDPK1 | 0.88266494 |
58 | PKN2 | 0.86434225 |
59 | IRAK1 | 0.84716917 |
60 | NUAK1 | 0.84403131 |
61 | MAP3K11 | 0.84103930 |
62 | WNK4 | 0.83472194 |
63 | LRRK2 | 0.82339904 |
64 | RIPK4 | 0.80607462 |
65 | MAP3K7 | 0.79006009 |
66 | AURKB | 0.78967463 |
67 | YES1 | 0.75452071 |
68 | TIE1 | 0.73543975 |
69 | NLK | 0.72483872 |
70 | PIK3CG | 0.71019599 |
71 | MAPK11 | 0.70989701 |
72 | CDK7 | 0.68131935 |
73 | KSR2 | 0.68102697 |
74 | MUSK | 0.67686916 |
75 | TYK2 | 0.66582823 |
76 | NME2 | 0.66469665 |
77 | MAPKAPK5 | 0.65880254 |
78 | MAP3K6 | 0.65316994 |
79 | MAP3K1 | 0.65302868 |
80 | CDK8 | 0.65081466 |
81 | MAP2K1 | 0.64693283 |
82 | PRKCI | 0.61251224 |
83 | PDK1 | 0.60071706 |
84 | PRKAA2 | 0.59545722 |
85 | ERBB2 | 0.58847248 |
86 | TTK | 0.58235231 |
87 | IKBKE | 0.56760104 |
88 | BLK | 0.55441148 |
89 | BMPR2 | 0.55076686 |
90 | JAK1 | 0.53745331 |
91 | PRKACG | 0.53432908 |
92 | PTK2 | 0.52872914 |
93 | KDR | 0.50366949 |
94 | PRKCA | 0.50346258 |
95 | BRSK2 | 0.50123734 |
96 | CASK | 0.48995899 |
97 | PIM1 | 0.47200331 |
98 | WEE1 | 0.46931255 |
99 | SRC | 0.44075140 |
100 | MAP3K3 | 0.43753267 |
101 | PRKCZ | 0.43419598 |
102 | DAPK2 | 0.42900647 |
103 | JAK3 | 0.40879082 |
104 | TRPM7 | 0.40402751 |
105 | VRK1 | 0.39262754 |
106 | DYRK1B | 0.38173101 |
107 | BMX | 0.38030230 |
108 | BMPR1B | 0.37043725 |
109 | ABL2 | 0.35990528 |
110 | LYN | 0.34865384 |
111 | AKT3 | 0.32728827 |
112 | IRAK3 | 0.32341911 |
113 | CDK9 | 0.32120673 |
114 | PAK2 | 0.31871248 |
115 | RAF1 | 0.31839825 |
116 | EPHA4 | 0.31716262 |
117 | EPHB1 | 0.31405807 |
118 | ITK | 0.31325023 |
119 | CSF1R | 0.30555185 |
120 | MAPKAPK2 | 0.30120404 |
121 | LCK | 0.30001068 |
122 | FYN | 0.29734298 |
123 | ZAP70 | 0.29458035 |
124 | MAP3K14 | 0.28473680 |
125 | CAMK2G | 0.28362926 |
126 | DYRK3 | 0.28168100 |
127 | CAMK2D | 0.27924883 |
128 | CDK6 | 0.27837964 |
129 | GRK1 | 0.27325144 |
130 | MAPK4 | 0.27249433 |
131 | PASK | 0.26960492 |
132 | CSK | 0.26740338 |
133 | JAK2 | 0.26393682 |
134 | SYK | 0.25843763 |
135 | RET | 0.25351439 |
136 | PRKCD | 0.23687813 |
137 | CSNK1A1 | 0.23059269 |
138 | PDGFRA | 0.20954298 |
139 | IGF1R | 0.20382214 |
140 | ADRBK2 | 0.19645436 |
141 | PRKCQ | 0.18503804 |
142 | NEK6 | 0.18307771 |
143 | PRKCE | 0.17758175 |
144 | PRKD2 | 0.14605651 |
145 | PHKG1 | 0.13095130 |
146 | PHKG2 | 0.13095130 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 4.59217805 |
2 | Fat digestion and absorption_Homo sapiens_hsa04975 | 4.27078242 |
3 | Mineral absorption_Homo sapiens_hsa04978 | 3.89592979 |
4 | Renin-angiotensin system_Homo sapiens_hsa04614 | 3.61350887 |
5 | Caffeine metabolism_Homo sapiens_hsa00232 | 3.60974394 |
6 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 3.53927792 |
7 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.23142149 |
8 | Galactose metabolism_Homo sapiens_hsa00052 | 2.94109993 |
9 | Arginine biosynthesis_Homo sapiens_hsa00220 | 2.81021845 |
10 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.74795269 |
11 | Folate biosynthesis_Homo sapiens_hsa00790 | 2.38411306 |
12 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 2.18607434 |
13 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.13887911 |
14 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 2.11667999 |
15 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 2.01866833 |
16 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.99154935 |
17 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.99135105 |
18 | Retinol metabolism_Homo sapiens_hsa00830 | 1.94791229 |
19 | Bile secretion_Homo sapiens_hsa04976 | 1.78146839 |
20 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.58591405 |
21 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.55727134 |
22 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.54080634 |
23 | Histidine metabolism_Homo sapiens_hsa00340 | 1.49601233 |
24 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.39247998 |
25 | Ribosome_Homo sapiens_hsa03010 | 1.34950122 |
26 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.29681572 |
27 | DNA replication_Homo sapiens_hsa03030 | 1.29226693 |
28 | Thyroid cancer_Homo sapiens_hsa05216 | 1.28742079 |
29 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.24898546 |
30 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.23551361 |
31 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.17535198 |
32 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.04950539 |
33 | Asthma_Homo sapiens_hsa05310 | 1.04866241 |
34 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.03600200 |
35 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.03439797 |
36 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.02240975 |
37 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.01202618 |
38 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.99236803 |
39 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.96883630 |
40 | Salmonella infection_Homo sapiens_hsa05132 | 0.92492396 |
41 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.90106845 |
42 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.89080272 |
43 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.86657895 |
44 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.86130488 |
45 | ABC transporters_Homo sapiens_hsa02010 | 0.85419864 |
46 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.85325058 |
47 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.85115750 |
48 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.84646275 |
49 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.82612065 |
50 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.81997635 |
51 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.81087769 |
52 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.79662604 |
53 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.77781482 |
54 | Allograft rejection_Homo sapiens_hsa05330 | 0.75406164 |
55 | Hepatitis C_Homo sapiens_hsa05160 | 0.73627023 |
56 | Leishmaniasis_Homo sapiens_hsa05140 | 0.73239291 |
57 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.72900853 |
58 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.71875229 |
59 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.71197422 |
60 | Peroxisome_Homo sapiens_hsa04146 | 0.70556602 |
61 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.68776844 |
62 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.68139429 |
63 | Pertussis_Homo sapiens_hsa05133 | 0.67269331 |
64 | Sulfur relay system_Homo sapiens_hsa04122 | 0.66735267 |
65 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.65213433 |
66 | Influenza A_Homo sapiens_hsa05164 | 0.64423724 |
67 | Mismatch repair_Homo sapiens_hsa03430 | 0.64380659 |
68 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.63755794 |
69 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.63675781 |
70 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.63197710 |
71 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.59751266 |
72 | Legionellosis_Homo sapiens_hsa05134 | 0.57276571 |
73 | Purine metabolism_Homo sapiens_hsa00230 | 0.56386632 |
74 | Platelet activation_Homo sapiens_hsa04611 | 0.55983568 |
75 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.55695684 |
76 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.55201326 |
77 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.54223116 |
78 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.53038285 |
79 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.50600221 |
80 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.50318078 |
81 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.50275578 |
82 | Shigellosis_Homo sapiens_hsa05131 | 0.49671936 |
83 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.49564698 |
84 | Renin secretion_Homo sapiens_hsa04924 | 0.49050563 |
85 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.48753827 |
86 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.47630082 |
87 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.46906777 |
88 | Base excision repair_Homo sapiens_hsa03410 | 0.46764956 |
89 | Other glycan degradation_Homo sapiens_hsa00511 | 0.46573277 |
90 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.46133744 |
91 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.45371238 |
92 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.44491790 |
93 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.42788948 |
94 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.41890953 |
95 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.41682005 |
96 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.41033577 |
97 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.40696224 |
98 | Tight junction_Homo sapiens_hsa04530 | 0.40490475 |
99 | Carbon metabolism_Homo sapiens_hsa01200 | 0.40260251 |
100 | Insulin secretion_Homo sapiens_hsa04911 | 0.37144292 |
101 | Apoptosis_Homo sapiens_hsa04210 | 0.35994817 |
102 | Insulin resistance_Homo sapiens_hsa04931 | 0.35667999 |
103 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.35233134 |
104 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.34635081 |
105 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.34244138 |
106 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.32954110 |
107 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.32823943 |
108 | Bladder cancer_Homo sapiens_hsa05219 | 0.32635372 |
109 | Metabolic pathways_Homo sapiens_hsa01100 | 0.32601276 |
110 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.32025001 |
111 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.31726977 |
112 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.30703073 |
113 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.30558125 |
114 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.28380715 |
115 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.28019199 |
116 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.28005600 |
117 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.27699500 |
118 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.24725963 |
119 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.24656681 |
120 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.23108827 |
121 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.22154061 |
122 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.21929086 |
123 | Hepatitis B_Homo sapiens_hsa05161 | 0.21472794 |
124 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.21301712 |
125 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.20884591 |
126 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.20715401 |
127 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.19309927 |
128 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.19237242 |
129 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.18640116 |
130 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.18603181 |
131 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.18186655 |
132 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.17517319 |
133 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.16781841 |
134 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.16511298 |
135 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.16010932 |
136 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.14957848 |
137 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.12759756 |
138 | Cocaine addiction_Homo sapiens_hsa05030 | 0.11218786 |
139 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.10826516 |
140 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.08387579 |