MVB12A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.61880884
2protein insertion into membrane (GO:0051205)4.41129396
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.25024806
4L-phenylalanine metabolic process (GO:0006558)4.25024806
5ribosomal small subunit assembly (GO:0000028)4.21539689
6ATP synthesis coupled proton transport (GO:0015986)4.20164495
7energy coupled proton transport, down electrochemical gradient (GO:0015985)4.20164495
8L-phenylalanine catabolic process (GO:0006559)4.09062218
9erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.09062218
10DNA deamination (GO:0045006)4.07737101
11metallo-sulfur cluster assembly (GO:0031163)3.92332644
12iron-sulfur cluster assembly (GO:0016226)3.92332644
13purine deoxyribonucleotide catabolic process (GO:0009155)3.78780956
14pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.78381651
15negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.77073787
16GTP biosynthetic process (GO:0006183)3.74644759
17base-excision repair, AP site formation (GO:0006285)3.65342947
18chaperone-mediated protein transport (GO:0072321)3.62350133
19antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.59541090
20antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.59541090
21viral transcription (GO:0019083)3.56538112
22deoxyribonucleotide catabolic process (GO:0009264)3.55386853
23aromatic amino acid family catabolic process (GO:0009074)3.51332004
24SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.51050008
25protein maturation by protein folding (GO:0022417)3.50567955
26negative regulation of DNA-templated transcription, elongation (GO:0032785)3.50564952
27UTP biosynthetic process (GO:0006228)3.49143444
28inner mitochondrial membrane organization (GO:0007007)3.43170561
29negative regulation of B cell apoptotic process (GO:0002903)3.42725721
30translational termination (GO:0006415)3.42347857
31guanosine-containing compound biosynthetic process (GO:1901070)3.41228587
32protein targeting to ER (GO:0045047)3.40831278
33glycine metabolic process (GO:0006544)3.40690673
34cotranslational protein targeting to membrane (GO:0006613)3.39406053
35serine family amino acid biosynthetic process (GO:0009070)3.34849557
36positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.34627525
37cysteine metabolic process (GO:0006534)3.33590602
38deoxyribose phosphate catabolic process (GO:0046386)3.31082880
39protein localization to endoplasmic reticulum (GO:0070972)3.27006081
40protein complex biogenesis (GO:0070271)3.25161748
41sulfur amino acid catabolic process (GO:0000098)3.25034769
42glyoxylate metabolic process (GO:0046487)3.22909191
43regulation of mitochondrial translation (GO:0070129)3.20854387
44pyrimidine nucleotide catabolic process (GO:0006244)3.18938907
45establishment of protein localization to endoplasmic reticulum (GO:0072599)3.18754682
46tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.18068982
47RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.18068982
48tRNA modification (GO:0006400)3.17960034
49mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.17831188
50translational elongation (GO:0006414)3.16761053
51antigen processing and presentation of endogenous antigen (GO:0019883)3.16258225
52indole-containing compound catabolic process (GO:0042436)3.13115420
53indolalkylamine catabolic process (GO:0046218)3.13115420
54tryptophan catabolic process (GO:0006569)3.13115420
55UTP metabolic process (GO:0046051)3.12599904
56pteridine-containing compound biosynthetic process (GO:0042559)3.10882249
57kynurenine metabolic process (GO:0070189)3.08933560
58mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.07919776
59mitochondrial respiratory chain complex I assembly (GO:0032981)3.07919776
60NADH dehydrogenase complex assembly (GO:0010257)3.07919776
61folic acid-containing compound biosynthetic process (GO:0009396)3.04139795
62L-serine metabolic process (GO:0006563)3.03537637
63triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.01902736
64UV protection (GO:0009650)3.01129734
65CTP biosynthetic process (GO:0006241)3.00910247
66CTP metabolic process (GO:0046036)3.00910247
67mitochondrial respiratory chain complex assembly (GO:0033108)2.99616996
68serine family amino acid metabolic process (GO:0009069)2.99264113
69sequestering of actin monomers (GO:0042989)2.97277072
70tryptophan metabolic process (GO:0006568)2.95351050
71mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.94406677
72pyrimidine nucleoside salvage (GO:0043097)2.93387233
73pyrimidine-containing compound salvage (GO:0008655)2.93387233
74pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.91826543
75intestinal cholesterol absorption (GO:0030299)2.90953896
76aldehyde catabolic process (GO:0046185)2.90662672
77electron transport chain (GO:0022900)2.90407456
78respiratory electron transport chain (GO:0022904)2.90397339
79mannosylation (GO:0097502)2.88027608
80pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.87851426
81purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.86918339
82pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.86588993
83Golgi transport vesicle coating (GO:0048200)2.86571247
84COPI coating of Golgi vesicle (GO:0048205)2.86571247
85purine nucleoside triphosphate biosynthetic process (GO:0009145)2.85923237
86pseudouridine synthesis (GO:0001522)2.85863816
87pentose metabolic process (GO:0019321)2.84389023
88positive regulation of T cell apoptotic process (GO:0070234)2.83104885
89valine metabolic process (GO:0006573)2.82369543
90ribosomal small subunit biogenesis (GO:0042274)2.81196841
91signal peptide processing (GO:0006465)2.78411487
922-deoxyribonucleotide metabolic process (GO:0009394)2.78245212
93positive regulation of lymphocyte apoptotic process (GO:0070230)2.77265643
94pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.76796152
95nucleoside salvage (GO:0043174)2.76790663
96cytochrome complex assembly (GO:0017004)2.75715310
97aromatic amino acid family metabolic process (GO:0009072)2.74456667
98high-density lipoprotein particle remodeling (GO:0034375)2.72922631
99pentose-phosphate shunt (GO:0006098)2.71848241
100viral life cycle (GO:0019058)2.71709271
101bile acid biosynthetic process (GO:0006699)2.71605113
102cellular response to interferon-beta (GO:0035458)2.70776526
103purine deoxyribonucleotide metabolic process (GO:0009151)2.70440163
104tetrahydrofolate metabolic process (GO:0046653)2.69237769
105protein targeting to mitochondrion (GO:0006626)2.68649357
106cellular response to exogenous dsRNA (GO:0071360)2.68642180
107proline biosynthetic process (GO:0006561)2.68475584
108peptidyl-glutamic acid carboxylation (GO:0017187)2.68353857
109protein carboxylation (GO:0018214)2.68353857
110ribonucleoside triphosphate biosynthetic process (GO:0009201)2.68013959
111fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.66381723
112peptidyl-histidine modification (GO:0018202)2.65928235
113chaperone mediated protein folding requiring cofactor (GO:0051085)2.65536169
114serine family amino acid catabolic process (GO:0009071)2.65129559
115establishment of protein localization to mitochondrion (GO:0072655)2.64589039
116pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.62954513
117alpha-linolenic acid metabolic process (GO:0036109)2.60906792
118tRNA processing (GO:0008033)2.60616553
119regulation of cholesterol esterification (GO:0010872)2.60380896
120urea metabolic process (GO:0019627)2.60204413
121urea cycle (GO:0000050)2.60204413
122homocysteine metabolic process (GO:0050667)2.59659089
123ATP biosynthetic process (GO:0006754)2.59215259
124regulation of B cell apoptotic process (GO:0002902)2.59113189
125translational initiation (GO:0006413)2.59078968
126respiratory chain complex IV assembly (GO:0008535)2.59077181
127transcription elongation from RNA polymerase III promoter (GO:0006385)2.58997407
128termination of RNA polymerase III transcription (GO:0006386)2.58997407
129mitochondrial calcium ion transport (GO:0006851)2.58702334
130negative regulation of fibrinolysis (GO:0051918)2.56567811
131negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.56291361
132deoxyribose phosphate metabolic process (GO:0019692)2.55600130
133cellular component biogenesis (GO:0044085)2.54570691
134viral protein processing (GO:0019082)2.54231435
135nucleotide transmembrane transport (GO:1901679)2.53769968
136deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.51678090
137NADPH regeneration (GO:0006740)2.51486039
138nitrogen cycle metabolic process (GO:0071941)2.50808634
139nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.50355930
140cellular protein complex disassembly (GO:0043624)2.50314580
141establishment of protein localization to mitochondrial membrane (GO:0090151)2.48888747
142folic acid metabolic process (GO:0046655)2.48087273
143maturation of SSU-rRNA (GO:0030490)2.47666769
144GDP-mannose metabolic process (GO:0019673)2.47489808
145nucleotide salvage (GO:0043173)2.46525513
146formation of translation preinitiation complex (GO:0001731)2.46200382
147cellular modified amino acid catabolic process (GO:0042219)2.46072663
148maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.45960649
149imidazole-containing compound metabolic process (GO:0052803)2.45472299
150protein retention in ER lumen (GO:0006621)2.44034743
151response to interferon-beta (GO:0035456)2.43993782
152proline metabolic process (GO:0006560)2.42705291
153phospholipid efflux (GO:0033700)2.41757901
154protein-lipid complex remodeling (GO:0034368)2.41570267
155macromolecular complex remodeling (GO:0034367)2.41570267
156plasma lipoprotein particle remodeling (GO:0034369)2.41570267
157one-carbon metabolic process (GO:0006730)2.41190716
158pteridine-containing compound metabolic process (GO:0042558)2.40814722
159translation (GO:0006412)2.39700840
160amino-acid betaine metabolic process (GO:0006577)2.39067884
161positive regulation of triglyceride lipase activity (GO:0061365)2.36463429
162positive regulation of lipoprotein lipase activity (GO:0051006)2.36463429
163alpha-amino acid catabolic process (GO:1901606)2.35934256
164reverse cholesterol transport (GO:0043691)2.35552958
165regulation of triglyceride catabolic process (GO:0010896)2.35409711
166antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.35282490
167killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.35276500
168disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.35276500
169regulation of protein activation cascade (GO:2000257)2.34923880
170sulfur amino acid biosynthetic process (GO:0000097)2.34389337
171tyrosine metabolic process (GO:0006570)2.33822284
172Arp2/3 complex-mediated actin nucleation (GO:0034314)2.33689940
173lysine metabolic process (GO:0006553)2.33607449
174lysine catabolic process (GO:0006554)2.33607449
175folic acid-containing compound metabolic process (GO:0006760)2.33266997
176ethanol oxidation (GO:0006069)2.32046504
177deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.31838406
178bile acid metabolic process (GO:0008206)2.31540029

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.27035219
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.33508555
3IRF8_22096565_ChIP-ChIP_GC-B_Human2.82478974
4RXR_22158963_ChIP-Seq_LIVER_Mouse2.82317785
5E2F7_22180533_ChIP-Seq_HELA_Human2.76739326
6PPARA_22158963_ChIP-Seq_LIVER_Mouse2.74739246
7MYC_18555785_ChIP-Seq_MESCs_Mouse2.67858915
8CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.64348291
9PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.43356570
10EGR1_23403033_ChIP-Seq_LIVER_Mouse2.36549506
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.29209874
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.25403386
13LXR_22292898_ChIP-Seq_THP-1_Human2.24920687
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.21588358
15GABP_17652178_ChIP-ChIP_JURKAT_Human2.21558452
16CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.11577228
17MYC_18358816_ChIP-ChIP_MESCs_Mouse2.08874237
18KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.08629658
19BCL6_27268052_Chip-Seq_Bcells_Human2.03532028
20P68_20966046_ChIP-Seq_HELA_Human2.00896015
21TET1_21451524_ChIP-Seq_MESCs_Mouse2.00436983
22SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.99161179
23EST1_17652178_ChIP-ChIP_JURKAT_Human1.97475282
24CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.96166082
25ETS1_20019798_ChIP-Seq_JURKAT_Human1.96151696
26SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.94964714
27ELF1_20517297_ChIP-Seq_JURKAT_Human1.92985245
28IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.90612410
29FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.89199055
30DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.81777284
31TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.78613591
32LXR_22158963_ChIP-Seq_LIVER_Mouse1.77461342
33CREB1_15753290_ChIP-ChIP_HEK293T_Human1.76590129
34BCOR_27268052_Chip-Seq_Bcells_Human1.72297083
35RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.69184463
36MYC_19030024_ChIP-ChIP_MESCs_Mouse1.67362762
37ELK3_25401928_ChIP-Seq_HUVEC_Human1.66483900
38SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.64414457
39E2F1_18555785_ChIP-Seq_MESCs_Mouse1.63488220
40XRN2_22483619_ChIP-Seq_HELA_Human1.60402251
41NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.60218713
42E2F1_20622854_ChIP-Seq_HELA_Human1.58927130
43IRF8_21731497_ChIP-ChIP_J774_Mouse1.58280371
44EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.57112938
45VDR_23849224_ChIP-Seq_CD4+_Human1.55539146
46MYC_22102868_ChIP-Seq_BL_Human1.55502332
47FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.54505320
48MYC_19079543_ChIP-ChIP_MESCs_Mouse1.53673870
49MAF_26560356_Chip-Seq_TH2_Human1.53539588
50BP1_19119308_ChIP-ChIP_Hs578T_Human1.52784070
51FOXP1_21924763_ChIP-Seq_HESCs_Human1.50624777
52DCP1A_22483619_ChIP-Seq_HELA_Human1.50055882
53ERG_20887958_ChIP-Seq_HPC-7_Mouse1.49535648
54SRF_21415370_ChIP-Seq_HL-1_Mouse1.48142748
55PHF8_20622854_ChIP-Seq_HELA_Human1.47574899
56CTCF_18555785_ChIP-Seq_MESCs_Mouse1.47539355
57E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.46603387
58MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.46225720
59VDR_21846776_ChIP-Seq_THP-1_Human1.44535797
60TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.43895285
61FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.43757581
62HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.43248815
63YY1_22570637_ChIP-Seq_MALME-3M_Human1.43092453
64SA1_27219007_Chip-Seq_ERYTHROID_Human1.42734497
65HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.42693928
66SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.42196513
67NELFA_20434984_ChIP-Seq_ESCs_Mouse1.41468027
68CTCF_26484167_Chip-Seq_Bcells_Mouse1.41373329
69GABP_19822575_ChIP-Seq_HepG2_Human1.39736406
70FOXP3_21729870_ChIP-Seq_TREG_Human1.39503752
71RACK7_27058665_Chip-Seq_MCF-7_Human1.37618097
72RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.36663516
73SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.35522197
74CTCF_20526341_ChIP-Seq_ESCs_Human1.35296154
75CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.35223852
76PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.34810275
77MYB_21317192_ChIP-Seq_ERMYB_Mouse1.34570228
78TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32013001
79SPI1_23547873_ChIP-Seq_NB4_Human1.31862235
80HOXB4_20404135_ChIP-ChIP_EML_Mouse1.31338184
81ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.30814766
82SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.30781950
83CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.29559679
84STAT3_1855785_ChIP-Seq_MESCs_Mouse1.29555083
85RARB_24833708_ChIP-Seq_LIVER_Mouse1.29405003
86SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.29178451
87CIITA_25753668_ChIP-Seq_RAJI_Human1.28170269
88CTCF_27219007_Chip-Seq_ERYTHROID_Human1.28098234
89SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.27688232
90IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.26785250
91STAT4_19710469_ChIP-ChIP_TH1__Mouse1.24840419
92SA1_27219007_Chip-Seq_Bcells_Human1.24505270
93ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.23991937
94STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.22089510
95FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.21809717
96CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.21453455
97ZFX_18555785_ChIP-Seq_MESCs_Mouse1.17893277
98FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.17421797
99CTCF_21964334_Chip-Seq_Bcells_Human1.17215354
100GATA1_22383799_ChIP-Seq_G1ME_Mouse1.16594885
101EGR1_19374776_ChIP-ChIP_THP-1_Human1.15629182
102CTCF_27219007_Chip-Seq_Bcells_Human1.15168373
103SMC4_20622854_ChIP-Seq_HELA_Human1.15017646
104CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.14507919
105HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.13637621
106RARA_24833708_ChIP-Seq_LIVER_Mouse1.12736464
107TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.12246247
108BRD4_27068464_Chip-Seq_AML-cells_Mouse1.12003511
109TP63_17297297_ChIP-ChIP_HaCaT_Human1.11897126
110P300_27268052_Chip-Seq_Bcells_Human1.11369617
111HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.11054551
112TFEB_21752829_ChIP-Seq_HELA_Human1.11021766
113SCL_19346495_ChIP-Seq_HPC-7_Human1.10369326
114KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.10191148
115PU.1_20513432_ChIP-Seq_Bcells_Mouse1.09824466
116KDM5A_27292631_Chip-Seq_BREAST_Human1.09783897
117MAF_26560356_Chip-Seq_TH1_Human1.09452998
118THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.07889995
119PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.07672803
120TP53_22127205_ChIP-Seq_IMR90_Human1.07614681
121KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.06601208
122RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.06380993
123SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.06304503
124GATA1_22025678_ChIP-Seq_K562_Human1.05685266
125NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.04771381
126MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.04117718
127RUNX1_22412390_ChIP-Seq_EML_Mouse1.03178994
128GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.02129407
129CTCF_21964334_ChIP-Seq_BJAB-B_Human1.01833851
130SPI1_20517297_ChIP-Seq_HL60_Human1.01522312
131GATA2_22383799_ChIP-Seq_G1ME_Mouse1.00186342
132YY1_21170310_ChIP-Seq_MESCs_Mouse0.99844919
133THAP11_20581084_ChIP-Seq_MESCs_Mouse0.99607464
134BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.99481766
135CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.98269255
136RARG_19884340_ChIP-ChIP_MEFs_Mouse0.97512062
137TTF2_22483619_ChIP-Seq_HELA_Human0.97379258
138SRY_22984422_ChIP-ChIP_TESTIS_Rat0.95709583
139UTX_26944678_Chip-Seq_JUKART_Human0.94542691
140CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.93993771
141MYB_26560356_Chip-Seq_TH1_Human0.93265921
142MYB_26560356_Chip-Seq_TH2_Human0.92800137
143VDR_24763502_ChIP-Seq_THP-1_Human0.91944854
144E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.91909141
145PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91203904
146POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.91181906
147NANOG_18555785_ChIP-Seq_MESCs_Mouse0.91176474
148GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.90430409
149CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.90396666

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system4.26085884
2MP0005360_urolithiasis3.88906250
3MP0005365_abnormal_bile_salt3.64579437
4MP0003806_abnormal_nucleotide_metabolis3.41139825
5MP0005085_abnormal_gallbladder_physiolo3.25346375
6MP0009840_abnormal_foam_cell3.09293867
7MP0005083_abnormal_biliary_tract2.83932744
8MP0000372_irregular_coat_pigmentation2.64031856
9MP0003136_yellow_coat_color2.61852497
10MP0001666_abnormal_nutrient_absorption2.44344581
11MP0001835_abnormal_antigen_presentation2.32532946
12MP0008875_abnormal_xenobiotic_pharmacok2.30684414
13MP0003186_abnormal_redox_activity2.15934289
14MP0003191_abnormal_cellular_cholesterol2.02287022
15MP0009785_altered_susceptibility_to2.01892216
16MP0000685_abnormal_immune_system2.01038379
17MP0003436_decreased_susceptibility_to1.98039409
18MP0001986_abnormal_taste_sensitivity1.89288323
19MP0000678_abnormal_parathyroid_gland1.85782267
20MP0010329_abnormal_lipoprotein_level1.82845919
21MP0005332_abnormal_amino_acid1.81354351
22MP0004858_abnormal_nervous_system1.81202960
23MP0003195_calcinosis1.77485456
24MP0003252_abnormal_bile_duct1.75286330
25MP0002163_abnormal_gland_morphology1.64798869
26MP0009278_abnormal_bone_marrow1.64330728
27MP0005025_abnormal_response_to1.62108735
28MP0000609_abnormal_liver_physiology1.58319639
29MP0000015_abnormal_ear_pigmentation1.58123481
30MP0003303_peritoneal_inflammation1.57916081
31MP0002138_abnormal_hepatobiliary_system1.55768009
32MP0001764_abnormal_homeostasis1.55522653
33MP0005671_abnormal_response_to1.55288819
34MP0003693_abnormal_embryo_hatching1.54790453
35MP0005319_abnormal_enzyme/_coenzyme1.52270319
36MP0009643_abnormal_urine_homeostasis1.50771528
37MP0000013_abnormal_adipose_tissue1.50317214
38MP0003786_premature_aging1.50285709
39MP0008469_abnormal_protein_level1.50233567
40MP0009333_abnormal_splenocyte_physiolog1.49294242
41MP0000681_abnormal_thyroid_gland1.49182093
42MP0006054_spinal_hemorrhage1.45682714
43MP0002653_abnormal_ependyma_morphology1.43961173
44MP0005220_abnormal_exocrine_pancreas1.42548091
45MP0005464_abnormal_platelet_physiology1.42264536
46MP0002148_abnormal_hypersensitivity_rea1.41585542
47MP0002396_abnormal_hematopoietic_system1.41418544
48MP0005174_abnormal_tail_pigmentation1.40658212
49MP0005171_absent_coat_pigmentation1.40469608
50MP0001853_heart_inflammation1.39913007
51MP0005000_abnormal_immune_tolerance1.39111894
52MP0001800_abnormal_humoral_immune1.38253203
53MP0004019_abnormal_vitamin_homeostasis1.37879569
54MP0001661_extended_life_span1.37453709
55MP0009379_abnormal_foot_pigmentation1.36999261
56MP0005058_abnormal_lysosome_morphology1.36403899
57MP0002419_abnormal_innate_immunity1.36363949
58MP0001845_abnormal_inflammatory_respons1.34893381
59MP0004381_abnormal_hair_follicle1.34564936
60MP0010155_abnormal_intestine_physiology1.34186333
61MP0003724_increased_susceptibility_to1.32400480
62MP0002723_abnormal_immune_serum1.31691270
63MP0003763_abnormal_thymus_physiology1.30091412
64MP0001919_abnormal_reproductive_system1.29893607
65MP0002452_abnormal_antigen_presenting1.27195341
66MP0003646_muscle_fatigue1.26537660
67MP0001905_abnormal_dopamine_level1.25631336
68MP0002102_abnormal_ear_morphology1.25328799
69MP0001663_abnormal_digestive_system1.25210278
70MP0000750_abnormal_muscle_regeneration1.25097853
71MP0000343_altered_response_to1.23858406
72MP0001790_abnormal_immune_system1.22862569
73MP0005387_immune_system_phenotype1.22862569
74MP0006036_abnormal_mitochondrial_physio1.21524124
75MP0002166_altered_tumor_susceptibility1.20299199
76MP0003315_abnormal_perineum_morphology1.19769939
77MP0000598_abnormal_liver_morphology1.19731020
78MP0000003_abnormal_adipose_tissue1.19527828
79MP0002420_abnormal_adaptive_immunity1.19264224
80MP0001819_abnormal_immune_cell1.18193813
81MP0001727_abnormal_embryo_implantation1.17465941
82MP0005084_abnormal_gallbladder_morpholo1.16850754
83MP0001873_stomach_inflammation1.16682501
84MP0004947_skin_inflammation1.16266501
85MP0000689_abnormal_spleen_morphology1.15369142
86MP0005410_abnormal_fertilization1.14854615
87MP0002118_abnormal_lipid_homeostasis1.14744711
88MP0006035_abnormal_mitochondrial_morpho1.14567437
89MP0003656_abnormal_erythrocyte_physiolo1.14334667
90MP0003878_abnormal_ear_physiology1.13225384
91MP0005377_hearing/vestibular/ear_phenot1.13225384
92MP0002405_respiratory_system_inflammati1.13164660
93MP0003868_abnormal_feces_composition1.12943657
94MP0009764_decreased_sensitivity_to1.12709474
95MP0000858_altered_metastatic_potential1.12101175
96MP0005167_abnormal_blood-brain_barrier1.12023220
97MP0000490_abnormal_crypts_of1.11973972
98MP0002277_abnormal_respiratory_mucosa1.09865389
99MP0005584_abnormal_enzyme/coenzyme_acti1.09860946
100MP0004957_abnormal_blastocyst_morpholog1.08786282
101MP0002398_abnormal_bone_marrow1.08163504
102MP0002722_abnormal_immune_system1.07519525
103MP0000716_abnormal_immune_system1.07032770
104MP0003705_abnormal_hypodermis_morpholog1.06815916
105MP0005408_hypopigmentation1.06224102
106MP0002095_abnormal_skin_pigmentation1.05765325
107MP0006292_abnormal_olfactory_placode1.05467116
108MP0005636_abnormal_mineral_homeostasis1.05434132
109MP0010030_abnormal_orbit_morphology1.03151695
110MP0002429_abnormal_blood_cell1.02636626
111MP0009763_increased_sensitivity_to1.00802776
112MP0005397_hematopoietic_system_phenotyp0.98717171
113MP0001545_abnormal_hematopoietic_system0.98717171
114MP0002006_tumorigenesis0.97168411
115MP0005670_abnormal_white_adipose0.96894808
116MP0001533_abnormal_skeleton_physiology0.96510889
117MP0003172_abnormal_lysosome_physiology0.96426608
118MP0006082_CNS_inflammation0.95198726
119MP0005257_abnormal_intraocular_pressure0.91432251
120MP0005451_abnormal_body_composition0.91043892
121MP0005389_reproductive_system_phenotype0.89443503
122MP0010352_gastrointestinal_tract_polyps0.89175070
123MP0005551_abnormal_eye_electrophysiolog0.89028664
124MP0002136_abnormal_kidney_physiology0.87670990
125MP0004782_abnormal_surfactant_physiolog0.87171961
126MP0005075_abnormal_melanosome_morpholog0.86799400
127MP0002132_abnormal_respiratory_system0.84910985
128MP0002019_abnormal_tumor_incidence0.83305927
129MP0000538_abnormal_urinary_bladder0.81681281
130MP0005390_skeleton_phenotype0.81284658
131MP0001756_abnormal_urination0.81010090
132MP0005023_abnormal_wound_healing0.80538250
133MP0009642_abnormal_blood_homeostasis0.78990059
134MP0000537_abnormal_urethra_morphology0.78836240
135MP0005381_digestive/alimentary_phenotyp0.78723404
136MP0009765_abnormal_xenobiotic_induced0.77070356
137MP0003011_delayed_dark_adaptation0.75444106
138MP0002693_abnormal_pancreas_physiology0.74126084
139MP0009697_abnormal_copulation0.73380982
140MP0003866_abnormal_defecation0.73363909
141MP0008007_abnormal_cellular_replicative0.72516375
142MP0000358_abnormal_cell_content/0.70000866
143MP0000465_gastrointestinal_hemorrhage0.69173826
144MP0005376_homeostasis/metabolism_phenot0.67138431
145MP0002877_abnormal_melanocyte_morpholog0.66847854
146MP0002933_joint_inflammation0.66677428

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)4.95193252
2Abnormality of monocarboxylic acid metabolism (HP:0010996)4.05603221
3Abnormal mitochondria in muscle tissue (HP:0008316)3.92885133
4Mitochondrial inheritance (HP:0001427)3.91310026
5Hepatocellular necrosis (HP:0001404)3.68466584
6Intrahepatic cholestasis (HP:0001406)3.64889336
7Increased intramyocellular lipid droplets (HP:0012240)3.61863086
8Increased muscle lipid content (HP:0009058)3.59911415
9Acute necrotizing encephalopathy (HP:0006965)3.58590763
10Abnormality of glycosphingolipid metabolism (HP:0004343)3.49995249
11Abnormality of glycolipid metabolism (HP:0010969)3.49995249
12Abnormality of liposaccharide metabolism (HP:0010968)3.49995249
13Hypoglycemic coma (HP:0001325)3.47948919
14Hypobetalipoproteinemia (HP:0003563)3.46945518
15Increased CSF lactate (HP:0002490)3.38846143
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.33265301
17Xanthomatosis (HP:0000991)3.31941454
18Acute encephalopathy (HP:0006846)3.20033374
19Prolonged partial thromboplastin time (HP:0003645)3.15721644
20Deep venous thrombosis (HP:0002625)3.13623246
21Elevated erythrocyte sedimentation rate (HP:0003565)3.06496086
22Testicular atrophy (HP:0000029)3.05918176
23Abnormality of pyrimidine metabolism (HP:0004353)3.00088413
24Abnormality of cells of the erythroid lineage (HP:0012130)2.99386587
25Renal Fanconi syndrome (HP:0001994)2.98606523
26Abnormality of the intrinsic pathway (HP:0010989)2.97430304
27Generalized aminoaciduria (HP:0002909)2.96638384
28Hyperammonemia (HP:0001987)2.91928886
29Progressive microcephaly (HP:0000253)2.90976122
30Abnormal number of erythroid precursors (HP:0012131)2.89374247
31Decreased electroretinogram (ERG) amplitude (HP:0000654)2.88600503
32Mesangial abnormality (HP:0001966)2.87928711
33Lactic acidosis (HP:0003128)2.82437691
34Congenital stationary night blindness (HP:0007642)2.77186082
35Abnormality of fatty-acid metabolism (HP:0004359)2.77169692
36Abnormality of the common coagulation pathway (HP:0010990)2.76284821
37Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.75249252
38Reduced antithrombin III activity (HP:0001976)2.74999439
39Thrombocytosis (HP:0001894)2.72446895
40Lipid accumulation in hepatocytes (HP:0006561)2.71424747
41Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.68526189
42Increased hepatocellular lipid droplets (HP:0006565)2.67993801
43Vacuolated lymphocytes (HP:0001922)2.67330945
44Ketosis (HP:0001946)2.64833172
45Fat malabsorption (HP:0002630)2.62376205
46Joint hemorrhage (HP:0005261)2.58333079
47Ragged-red muscle fibers (HP:0003200)2.57099571
48Increased serum lactate (HP:0002151)2.56613716
49Progressive macrocephaly (HP:0004481)2.55731399
50Abnormality of glutamine family amino acid metabolism (HP:0010902)2.55639459
51Hyperlipoproteinemia (HP:0010980)2.53771894
52Abnormality of dicarboxylic acid metabolism (HP:0010995)2.52895775
53Dicarboxylic aciduria (HP:0003215)2.52895775
54Exercise intolerance (HP:0003546)2.52196517
55Reticulocytopenia (HP:0001896)2.51193724
56Hyperglycinuria (HP:0003108)2.49185953
57Absent rod-and cone-mediated responses on ERG (HP:0007688)2.48966742
58Abnormality of sulfur amino acid metabolism (HP:0004339)2.46306179
59Rough bone trabeculation (HP:0100670)2.46276313
60Hypertensive crisis (HP:0100735)2.44855170
61Petechiae (HP:0000967)2.44334551
62Hypolipoproteinemia (HP:0010981)2.42759793
63Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.40438792
64Decreased activity of mitochondrial respiratory chain (HP:0008972)2.40438792
65Late onset (HP:0003584)2.40426767
66Hyperbilirubinemia (HP:0002904)2.33612472
67Hyperglycinemia (HP:0002154)2.33564876
68Hepatic necrosis (HP:0002605)2.33166857
69Abnormality of aspartate family amino acid metabolism (HP:0010899)2.31407240
70Steatorrhea (HP:0002570)2.31155682
71Optic disc pallor (HP:0000543)2.30034721
72Abnormality of nucleobase metabolism (HP:0010932)2.29882477
73Prolonged neonatal jaundice (HP:0006579)2.29667390
74Abnormality of methionine metabolism (HP:0010901)2.27334176
753-Methylglutaconic aciduria (HP:0003535)2.27175570
76Ketoacidosis (HP:0001993)2.22964382
77Recurrent bacterial skin infections (HP:0005406)2.22906922
78Abnormality of polysaccharide metabolism (HP:0011012)2.22789257
79Abnormality of glycosaminoglycan metabolism (HP:0004371)2.22789257
80Abnormality of mucopolysaccharide metabolism (HP:0011020)2.22789257
81Myositis (HP:0100614)2.21522487
82Abnormality of serine family amino acid metabolism (HP:0010894)2.20481365
83Abnormality of glycine metabolism (HP:0010895)2.20481365
84Recurrent gram-negative bacterial infections (HP:0005420)2.19955131
85Hemorrhage of the eye (HP:0011885)2.16921000
86Eczematoid dermatitis (HP:0000976)2.16602614
87Complement deficiency (HP:0004431)2.16395261
88Increased serum ferritin (HP:0003281)2.14968228
89Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.14622053
90Pancreatitis (HP:0001733)2.13766659
91Respiratory difficulties (HP:0002880)2.13190124
92Cerebral palsy (HP:0100021)2.12518029
93Increased neuronal autofluorescent lipopigment (HP:0002074)2.11987619
94Abnormality of magnesium homeostasis (HP:0004921)2.11482017
95Pustule (HP:0200039)2.10575186
96Recurrent abscess formation (HP:0002722)2.09782563
97Squamous cell carcinoma (HP:0002860)2.09610090
98Systemic lupus erythematosus (HP:0002725)2.09321454
99Poikiloderma (HP:0001029)2.07509859
100Microretrognathia (HP:0000308)2.07143735
101Macrocytic anemia (HP:0001972)2.06448737
102Abnormality of iron homeostasis (HP:0011031)2.06345663
103Lethargy (HP:0001254)2.06340197
104Aplastic anemia (HP:0001915)2.06302187
105Gingival bleeding (HP:0000225)2.04785824
106Abnormality of T cell physiology (HP:0011840)2.03503157
107IgM deficiency (HP:0002850)2.03240168
108Abnormality of transition element cation homeostasis (HP:0011030)2.03169287
109Spastic diplegia (HP:0001264)2.03074742
110Exertional dyspnea (HP:0002875)2.02773269
111Multiple enchondromatosis (HP:0005701)2.02199940
112Type I transferrin isoform profile (HP:0003642)2.02130224
113Oral leukoplakia (HP:0002745)1.99702638
114Abnormality of serum amino acid levels (HP:0003112)1.98696688
115Abnormal trabecular bone morphology (HP:0100671)1.97636562
116Poor head control (HP:0002421)1.97593132
117Esophageal neoplasm (HP:0100751)1.97536124
118Neoplasm of head and neck (HP:0012288)1.97536124
119Abnormal protein glycosylation (HP:0012346)1.97450742
120Abnormal glycosylation (HP:0012345)1.97450742
121Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.97450742
122Abnormal protein N-linked glycosylation (HP:0012347)1.97450742
123Beaking of vertebral bodies (HP:0004568)1.96426698
124Emotional lability (HP:0000712)1.96265652
125Conjugated hyperbilirubinemia (HP:0002908)1.95439654
126Delayed CNS myelination (HP:0002188)1.95077721
127Abnormality of purine metabolism (HP:0004352)1.94779510
128Abnormality of complement system (HP:0005339)1.94378047
129Cerebral edema (HP:0002181)1.94253198
130Chronic otitis media (HP:0000389)1.93555198
131Dysautonomia (HP:0002459)1.93504531
132Epistaxis (HP:0000421)1.93337085
133Increased cerebral lipofuscin (HP:0011813)1.93031085
134Respiratory failure (HP:0002878)1.92724944
135Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.91923362
136Nausea (HP:0002018)1.91618249
137Joint stiffness (HP:0001387)1.90771770
138Abnormal rod and cone electroretinograms (HP:0008323)1.90225908
139Purpura (HP:0000979)1.89477320
140Pallor (HP:0000980)1.88924339
141Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.88210155
142Gout (HP:0001997)1.87712976
143Severe visual impairment (HP:0001141)1.87615624
144Hypoalphalipoproteinemia (HP:0003233)1.86668688
145Dysostosis multiplex (HP:0000943)1.83829711
146Hypoglycemic seizures (HP:0002173)1.83547514
147Abnormal platelet function (HP:0011869)1.82862127
148Impaired platelet aggregation (HP:0003540)1.82862127
149Abnormality of macrophages (HP:0004311)1.81802853
150Progressive neurologic deterioration (HP:0002344)1.80353129
151Metabolic acidosis (HP:0001942)1.79462248
152Abnormal cartilage morphology (HP:0002763)1.78465575
153Entropion (HP:0000621)1.78277221
154Agammaglobulinemia (HP:0004432)1.77909405
155Opisthotonus (HP:0002179)1.77078380
156Urinary glycosaminoglycan excretion (HP:0003541)1.76798166
157Mucopolysacchariduria (HP:0008155)1.76798166
158Microcytic anemia (HP:0001935)1.76457592
159Hyperthyroidism (HP:0000836)1.72104864
160Orchitis (HP:0100796)1.71951976
161Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.71154128
162Muscle fiber atrophy (HP:0100295)1.70807905
163Rib fusion (HP:0000902)1.69437617
164Severe muscular hypotonia (HP:0006829)1.68334636
165Obstructive lung disease (HP:0006536)1.68133988
166Chronic obstructive pulmonary disease (HP:0006510)1.68133988
167Aplasia/Hypoplasia of the sacrum (HP:0008517)1.65342223
168IgG deficiency (HP:0004315)1.64701142
169Microvesicular hepatic steatosis (HP:0001414)1.62213635
170Acute hepatic failure (HP:0006554)1.61515926
171Brittle hair (HP:0002299)1.59406846
172Increased IgM level (HP:0003496)1.58940194
173Nasal polyposis (HP:0100582)1.56906476

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN14.02724577
2BCKDK3.99795421
3NME23.66351476
4VRK23.42944135
5FLT32.53478816
6MAP4K12.50856393
7PIM22.47525620
8BLK2.26227657
9TBK12.16300972
10TESK22.16226682
11KDR2.15517236
12STK162.04990894
13ZAP701.88174784
14MAP3K101.88048049
15PKN21.84004583
16MAP4K21.82942535
17EIF2AK31.72051913
18TYK21.69748882
19EPHB21.68730837
20LIMK11.68323645
21MAPKAPK31.66328649
22TRIB31.65450053
23EEF2K1.63721447
24BUB11.61369550
25SCYL21.60198192
26KIT1.54758833
27FGFR41.44659673
28LRRK21.42162282
29ZAK1.41793388
30MAP3K111.38393823
31BTK1.38235684
32IKBKE1.35953394
33NEK91.34660608
34WEE11.33777676
35RPS6KB21.32838848
36TESK11.29663944
37ICK1.26731406
38MAP3K141.26642639
39NUAK11.26299305
40IKBKB1.25935160
41PASK1.24172908
42IRAK41.20383107
43JAK31.17657302
44TEC1.17490981
45PIK3CG1.17471012
46SIK11.15894914
47SMG11.15354313
48WNK41.14553231
49ACVR1B1.14017426
50MAP2K21.12988972
51EIF2AK11.11678316
52MAP2K71.08894881
53MAP2K31.08187886
54RPS6KA41.07501053
55IRAK31.06908562
56TAOK31.03605350
57PIM11.02655149
58EPHA20.97595381
59GRK60.97146663
60CSF1R0.95289865
61MAP3K30.94757570
62RPS6KA50.94622122
63BRSK20.94395653
64TXK0.94214613
65INSRR0.91030046
66STK100.89435482
67DYRK30.88835616
68VRK10.87937312
69TAOK20.87296500
70DYRK20.86268869
71TNK20.85642565
72MAPK110.84881612
73TLK10.84040027
74TGFBR10.83960883
75PAK40.82834970
76PTK60.81591245
77ADRBK20.81431234
78SYK0.80154355
79HIPK20.76602729
80NME10.76387369
81MST1R0.75236072
82CDK190.75053037
83NEK20.74945976
84ARAF0.71914415
85CHUK0.70823257
86CSNK1G30.70729901
87MAP3K80.69715162
88ABL20.68249893
89SIK20.67049741
90LYN0.66484985
91TGFBR20.65554863
92MAPK150.63497876
93CDK40.61564275
94CDK70.60777190
95RPS6KA20.60467380
96DAPK10.60368870
97LMTK20.60013384
98NLK0.59881209
99ILK0.58005483
100BRAF0.57998483
101DYRK1B0.57431461
102ITK0.56876983
103PAK10.56261934
104RPS6KA60.55186978
105CHEK20.54974381
106IRAK10.53454840
107FES0.52948880
108PRKG20.52524467
109MST40.52323674
110MATK0.51247345
111IRAK20.51016958
112MAP2K60.50959160
113MUSK0.50881240
114CSK0.49546334
115ADRBK10.48361544
116LCK0.48067859
117AURKB0.47943849
118RPS6KC10.47411552
119RPS6KL10.47411552
120PDK20.44470976
121BMPR1B0.44070592
122RAF10.43689699
123CSNK1A1L0.43137196
124JAK20.42710715
125JAK10.42696659
126CDK80.42417762
127PRKD30.41245307
128AURKA0.40870300
129MAPKAPK20.39985176
130PRKCQ0.39571367
131MYLK0.39555811
132BRSK10.39425180
133STK40.36839560
134DAPK30.35212016
135BMX0.33853879
136PRKCD0.33782904
137MAPKAPK50.33679019
138MARK30.33306977
139EIF2AK20.33227321
140PRKCI0.32701453
141CSNK2A10.32033587
142ATR0.31958891
143EPHB10.30933956

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030102.64936974
2Primary bile acid biosynthesis_Homo sapiens_hsa001202.55842937
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.27649572
4Folate biosynthesis_Homo sapiens_hsa007902.24720053
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.18377039
6Huntingtons disease_Homo sapiens_hsa050162.09180904
7Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.98299304
8Proteasome_Homo sapiens_hsa030501.97651977
9Pentose and glucuronate interconversions_Homo sapiens_hsa000401.92888835
10DNA replication_Homo sapiens_hsa030301.91849776
11Drug metabolism - other enzymes_Homo sapiens_hsa009831.89770995
12Sulfur relay system_Homo sapiens_hsa041221.86829914
13Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.84667703
14Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.84318817
15Alzheimers disease_Homo sapiens_hsa050101.78822663
16Selenocompound metabolism_Homo sapiens_hsa004501.77702547
17One carbon pool by folate_Homo sapiens_hsa006701.76439296
18Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.76145926
19Protein export_Homo sapiens_hsa030601.73027514
20Tryptophan metabolism_Homo sapiens_hsa003801.67051647
21Fatty acid degradation_Homo sapiens_hsa000711.62211058
22Peroxisome_Homo sapiens_hsa041461.53926771
23Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.53151671
24Arginine biosynthesis_Homo sapiens_hsa002201.51571289
25Cyanoamino acid metabolism_Homo sapiens_hsa004601.50450034
26Maturity onset diabetes of the young_Homo sapiens_hsa049501.50334644
27Pentose phosphate pathway_Homo sapiens_hsa000301.44174421
28Complement and coagulation cascades_Homo sapiens_hsa046101.42288310
29Mismatch repair_Homo sapiens_hsa034301.40388537
302-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.39739724
31Caffeine metabolism_Homo sapiens_hsa002321.38122018
32Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.37369170
33Histidine metabolism_Homo sapiens_hsa003401.35242772
34Biosynthesis of amino acids_Homo sapiens_hsa012301.34399690
35Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.34127539
36Pyrimidine metabolism_Homo sapiens_hsa002401.32860530
37Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.32319944
38Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.32308813
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.27810441
40Fat digestion and absorption_Homo sapiens_hsa049751.27393352
41Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.27201362
42Cysteine and methionine metabolism_Homo sapiens_hsa002701.24940388
43Carbon metabolism_Homo sapiens_hsa012001.24316661
44Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.23521381
45Nitrogen metabolism_Homo sapiens_hsa009101.22349070
46Chemical carcinogenesis_Homo sapiens_hsa052041.20776088
47Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.20329681
48Staphylococcus aureus infection_Homo sapiens_hsa051501.20274143
49Base excision repair_Homo sapiens_hsa034101.19936065
50Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.18599597
51Sulfur metabolism_Homo sapiens_hsa009201.17016059
52beta-Alanine metabolism_Homo sapiens_hsa004101.16840155
53Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.15706255
54Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.14955676
55Propanoate metabolism_Homo sapiens_hsa006401.14280724
56Glutathione metabolism_Homo sapiens_hsa004801.04388946
57Phenylalanine metabolism_Homo sapiens_hsa003601.04118175
58RNA polymerase_Homo sapiens_hsa030201.03825423
59Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.01768759
60Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.01278925
61Other glycan degradation_Homo sapiens_hsa005110.97889493
62Pyruvate metabolism_Homo sapiens_hsa006200.96790144
63Galactose metabolism_Homo sapiens_hsa000520.96204336
64Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.94395041
65Starch and sucrose metabolism_Homo sapiens_hsa005000.94327723
66Legionellosis_Homo sapiens_hsa051340.92640339
67Fructose and mannose metabolism_Homo sapiens_hsa000510.89757519
68Arginine and proline metabolism_Homo sapiens_hsa003300.88427462
69Antigen processing and presentation_Homo sapiens_hsa046120.87476975
70Tyrosine metabolism_Homo sapiens_hsa003500.86403492
71Asthma_Homo sapiens_hsa053100.84577705
72Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.83928767
73Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.83163591
74Retinol metabolism_Homo sapiens_hsa008300.82393963
75Allograft rejection_Homo sapiens_hsa053300.82121894
76Steroid hormone biosynthesis_Homo sapiens_hsa001400.81400282
77Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.80356550
78PPAR signaling pathway_Homo sapiens_hsa033200.79793735
79Fatty acid metabolism_Homo sapiens_hsa012120.79738976
80Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.79338581
81Primary immunodeficiency_Homo sapiens_hsa053400.77455433
82Autoimmune thyroid disease_Homo sapiens_hsa053200.77336457
83Nucleotide excision repair_Homo sapiens_hsa034200.74620358
84Fatty acid elongation_Homo sapiens_hsa000620.74485766
85Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.70130586
86Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.69952538
87Graft-versus-host disease_Homo sapiens_hsa053320.69574749
88N-Glycan biosynthesis_Homo sapiens_hsa005100.69071222
89Butanoate metabolism_Homo sapiens_hsa006500.68420766
90SNARE interactions in vesicular transport_Homo sapiens_hsa041300.67858127
91Homologous recombination_Homo sapiens_hsa034400.67427137
92Vitamin digestion and absorption_Homo sapiens_hsa049770.62972674
93Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.62730452
94Metabolic pathways_Homo sapiens_hsa011000.62615988
95Glycosaminoglycan degradation_Homo sapiens_hsa005310.62560778
96Spliceosome_Homo sapiens_hsa030400.59536984
97Shigellosis_Homo sapiens_hsa051310.58686936
98Cardiac muscle contraction_Homo sapiens_hsa042600.58092184
99Rheumatoid arthritis_Homo sapiens_hsa053230.57922695
100Steroid biosynthesis_Homo sapiens_hsa001000.57543303
101Ovarian steroidogenesis_Homo sapiens_hsa049130.56429717
102Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.56344814
103Leishmaniasis_Homo sapiens_hsa051400.56326336
104RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.54904767
105Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.54455321
106Toll-like receptor signaling pathway_Homo sapiens_hsa046200.54070050
107ABC transporters_Homo sapiens_hsa020100.53795376
108Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.53709369
109Fanconi anemia pathway_Homo sapiens_hsa034600.53355231
110Salmonella infection_Homo sapiens_hsa051320.53118615
111Measles_Homo sapiens_hsa051620.52676337
112Vibrio cholerae infection_Homo sapiens_hsa051100.52166487
113Systemic lupus erythematosus_Homo sapiens_hsa053220.52165077
114Lysosome_Homo sapiens_hsa041420.52076960
115Intestinal immune network for IgA production_Homo sapiens_hsa046720.50558415
116NF-kappa B signaling pathway_Homo sapiens_hsa040640.48678672
117Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.46617868
118Herpes simplex infection_Homo sapiens_hsa051680.46247558
119Parkinsons disease_Homo sapiens_hsa050120.42150476
120Arachidonic acid metabolism_Homo sapiens_hsa005900.41037347
121Oxidative phosphorylation_Homo sapiens_hsa001900.40534907
122Epstein-Barr virus infection_Homo sapiens_hsa051690.40087568
123p53 signaling pathway_Homo sapiens_hsa041150.38917754
124Apoptosis_Homo sapiens_hsa042100.37731292
125Collecting duct acid secretion_Homo sapiens_hsa049660.36911178
126Purine metabolism_Homo sapiens_hsa002300.35923504
127Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.34959161
128Influenza A_Homo sapiens_hsa051640.34061770
129Tuberculosis_Homo sapiens_hsa051520.28872994
130Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.27960951
131Hematopoietic cell lineage_Homo sapiens_hsa046400.27749477
132Sphingolipid metabolism_Homo sapiens_hsa006000.27704731
133Glycerophospholipid metabolism_Homo sapiens_hsa005640.26296902
134Pertussis_Homo sapiens_hsa051330.26115812
135Osteoclast differentiation_Homo sapiens_hsa043800.23375429
136Basal transcription factors_Homo sapiens_hsa030220.22621902

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