MVP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.22461195
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.22461195
3negative regulation of cell killing (GO:0031342)4.22419653
4negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.22419653
5antigen processing and presentation of endogenous antigen (GO:0019883)4.08089361
6low-density lipoprotein particle clearance (GO:0034383)3.82640130
7antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.36754326
8detection of other organism (GO:0098543)3.33782648
9detection of bacterium (GO:0016045)3.26761436
10regulation of cholesterol storage (GO:0010885)3.25075470
11positive regulation of interferon-alpha production (GO:0032727)3.17622314
12modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.17393410
13positive regulation by organism of defense response of other organism involved in symbiotic interact3.17393410
14modulation by symbiont of host immune response (GO:0052553)3.17393410
15positive regulation by symbiont of host defense response (GO:0052509)3.17393410
16modulation by symbiont of host defense response (GO:0052031)3.17393410
17modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.17393410
18bundle of His cell to Purkinje myocyte communication (GO:0086069)3.17330080
19positive regulation of p38MAPK cascade (GO:1900745)3.12680979
20growth hormone receptor signaling pathway (GO:0060396)3.09166402
21regulation of interferon-beta biosynthetic process (GO:0045357)3.06540370
22barbed-end actin filament capping (GO:0051016)3.05999778
23regulation of dendritic cell antigen processing and presentation (GO:0002604)3.05840285
24NIK/NF-kappaB signaling (GO:0038061)3.04353134
25negative regulation of interleukin-12 production (GO:0032695)3.03963263
26regulation of interferon-alpha production (GO:0032647)2.98554826
27detection of external biotic stimulus (GO:0098581)2.97281403
28apoptotic cell clearance (GO:0043277)2.96060773
29positive regulation of antigen processing and presentation (GO:0002579)2.91585535
30hemidesmosome assembly (GO:0031581)2.83824674
31neutrophil activation involved in immune response (GO:0002283)2.81841332
32positive regulation of Cdc42 GTPase activity (GO:0043089)2.81560376
33cell adhesion mediated by integrin (GO:0033627)2.78112739
34mannose metabolic process (GO:0006013)2.72837371
35positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.72143248
36regulation of antigen processing and presentation (GO:0002577)2.70414464
37germinal center formation (GO:0002467)2.70219420
38hepatocyte apoptotic process (GO:0097284)2.68947447
39regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.67212689
40protein localization to endosome (GO:0036010)2.66561557
41adhesion of symbiont to host cell (GO:0044650)2.66187282
42virion attachment to host cell (GO:0019062)2.66187282
43intestinal cholesterol absorption (GO:0030299)2.65486973
44negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.63767334
45regulation of T cell tolerance induction (GO:0002664)2.63036932
46positive regulation of natural killer cell differentiation (GO:0032825)2.62794411
47cellular response to growth hormone stimulus (GO:0071378)2.62581109
48regulation of integrin activation (GO:0033623)2.61351565
49regulation of extracellular matrix disassembly (GO:0010715)2.61155997
50macrophage activation involved in immune response (GO:0002281)2.59783255
51negative regulation of lipid storage (GO:0010888)2.58427161
52intestinal absorption (GO:0050892)2.57282035
53response to type I interferon (GO:0034340)2.56921130
54immunoglobulin mediated immune response (GO:0016064)2.56834938
55negative regulation of erythrocyte differentiation (GO:0045647)2.56642929
56regulation of tolerance induction (GO:0002643)2.55679323
57response to muramyl dipeptide (GO:0032495)2.54835336
58regulation of interleukin-12 biosynthetic process (GO:0045075)2.54348621
59cellular response to type I interferon (GO:0071357)2.53388769
60type I interferon signaling pathway (GO:0060337)2.53388769
61plasma lipoprotein particle clearance (GO:0034381)2.53066763
62UDP-N-acetylglucosamine metabolic process (GO:0006047)2.52591353
63JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.51219863
64leukocyte aggregation (GO:0070486)2.50846139
65positive regulation of lipid storage (GO:0010884)2.50713798
66regulation of mast cell degranulation (GO:0043304)2.50311212
67detection of biotic stimulus (GO:0009595)2.49937128
68response to peptidoglycan (GO:0032494)2.49662629
69regulation of leukocyte degranulation (GO:0043300)2.47323778
70regulation of T-helper 2 cell differentiation (GO:0045628)2.46920114
71adhesion of symbiont to host (GO:0044406)2.46837826
72tolerance induction (GO:0002507)2.46702293
73regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.46343380
74negative regulation of leukocyte mediated immunity (GO:0002704)2.45163634
75regulation of gamma-delta T cell activation (GO:0046643)2.44540374
76maintenance of gastrointestinal epithelium (GO:0030277)2.44417819
77positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.44371892
78negative regulation of lymphocyte mediated immunity (GO:0002707)2.43412632
79hypotonic response (GO:0006971)2.43397896
80myeloid dendritic cell differentiation (GO:0043011)2.42467891
81peptide catabolic process (GO:0043171)2.39179065
82regulation of type I interferon-mediated signaling pathway (GO:0060338)2.38977145
83negative regulation of innate immune response (GO:0045824)2.38851454
84regulation of myeloid leukocyte mediated immunity (GO:0002886)2.38803115
85regulation of RIG-I signaling pathway (GO:0039535)2.37278654
86regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.37260505
87cellular extravasation (GO:0045123)2.37230686
88regulation of T cell mediated cytotoxicity (GO:0001914)2.37058931
89phospholipid homeostasis (GO:0055091)2.37007542
90regulation of membrane protein ectodomain proteolysis (GO:0051043)2.36283378
91response to host (GO:0075136)2.35170041
92positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.35160483
93response to laminar fluid shear stress (GO:0034616)2.34879867
94positive regulation of interferon-beta production (GO:0032728)2.34572186
95phospholipid efflux (GO:0033700)2.32050996
96negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.30650168
97detection of molecule of bacterial origin (GO:0032490)2.30247706
98regulation of type 2 immune response (GO:0002828)2.30072137
99response to interferon-alpha (GO:0035455)2.29905035
100natural killer cell mediated cytotoxicity (GO:0042267)2.29827095
101natural killer cell mediated immunity (GO:0002228)2.29827095
102negative regulation of cytokine production involved in immune response (GO:0002719)2.29356793
103production of molecular mediator involved in inflammatory response (GO:0002532)2.28948286
104positive regulation of T cell mediated cytotoxicity (GO:0001916)2.28406512
105positive regulation of tolerance induction (GO:0002645)2.28193370
106negative regulation of type 2 immune response (GO:0002829)2.27496818
107regulation of cellular extravasation (GO:0002691)2.25802833
108pinocytosis (GO:0006907)2.25527732
109defense response to protozoan (GO:0042832)2.24551056
110regulation of cholesterol homeostasis (GO:2000188)2.24317688
111wound healing, spreading of epidermal cells (GO:0035313)2.24260496
112regulation of mast cell activation involved in immune response (GO:0033006)2.24009953
113regulation of B cell receptor signaling pathway (GO:0050855)2.23817765
114response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.23741713
115response to host immune response (GO:0052572)2.23741713
116positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.23461777
117regulation of necroptotic process (GO:0060544)2.23159545
118angiotensin maturation (GO:0002003)2.22651296
119lipoprotein metabolic process (GO:0042157)2.21786314
120regulation of sequestering of triglyceride (GO:0010889)2.21538362
121B cell mediated immunity (GO:0019724)2.21437961
122T-helper 1 type immune response (GO:0042088)2.20868473
123regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.20818315
124positive regulation of receptor recycling (GO:0001921)2.20461610
125negative regulation of interleukin-6 production (GO:0032715)2.19013690
126striated muscle atrophy (GO:0014891)2.18825979
127regulation of T-helper 1 cell differentiation (GO:0045625)2.18389348
128lipopolysaccharide-mediated signaling pathway (GO:0031663)2.18221043
129positive regulation of gamma-delta T cell activation (GO:0046645)2.18111560
130antigen processing and presentation via MHC class Ib (GO:0002475)2.18080193
131hydrogen peroxide biosynthetic process (GO:0050665)2.17566435
132interferon-gamma-mediated signaling pathway (GO:0060333)2.17529748
133positive regulation of type 2 immune response (GO:0002830)2.17397312
134negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.16450795
135neutrophil activation (GO:0042119)2.16269811
136positive regulation of cholesterol efflux (GO:0010875)2.15719374
137regulation of macrophage derived foam cell differentiation (GO:0010743)2.15668129
138macrophage activation (GO:0042116)2.15069791
139cellular response to interferon-gamma (GO:0071346)2.14670497
140positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.13723747
141regulation of natural killer cell mediated immunity (GO:0002715)2.13147222
142vascular endothelial growth factor signaling pathway (GO:0038084)2.12925471
143positive regulation of cellular amide metabolic process (GO:0034250)2.11886245
144positive regulation of cholesterol transport (GO:0032376)2.11648439
145positive regulation of sterol transport (GO:0032373)2.11648439
146granulocyte activation (GO:0036230)2.11136449
147positive regulation of reactive oxygen species metabolic process (GO:2000379)2.10467004
148regulation of p38MAPK cascade (GO:1900744)2.08800836
149retina vasculature morphogenesis in camera-type eye (GO:0061299)2.08780510
150regulation of triglyceride catabolic process (GO:0010896)2.08079613
151interferon-gamma secretion (GO:0072643)2.07050543
152cellular response to vitamin (GO:0071295)2.05923507
153cytokine secretion (GO:0050663)2.05741984
154regulation of podosome assembly (GO:0071801)2.05156794
155response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.05105466
156response to host defenses (GO:0052200)2.05105466

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.05239503
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.18069809
3IRF8_21731497_ChIP-ChIP_J774_Mouse3.31661271
4IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.19839253
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.14078385
6ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.09817537
7RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.74398723
8RXR_22158963_ChIP-Seq_LIVER_Mouse2.56750797
9PPARA_22158963_ChIP-Seq_LIVER_Mouse2.56434743
10* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.47669676
11BP1_19119308_ChIP-ChIP_Hs578T_Human2.46473352
12IRF8_27001747_Chip-Seq_BMDM_Mouse2.46000639
13SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.40428147
14RARG_19884340_ChIP-ChIP_MEFs_Mouse2.36219473
15STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.34098191
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.30800310
17LXR_22158963_ChIP-Seq_LIVER_Mouse2.28550073
18TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.27462153
19NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.24011287
20TRIM28_21343339_ChIP-Seq_HEK293_Human2.20841243
21STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.08994292
22KDM2B_26808549_Chip-Seq_SUP-B15_Human2.07490618
23STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.91324808
24CLOCK_20551151_ChIP-Seq_293T_Human1.90532530
25MYB_21317192_ChIP-Seq_ERMYB_Mouse1.90515221
26FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.85324145
27ESR1_21235772_ChIP-Seq_MCF-7_Human1.84952286
28IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.83502283
29* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.81947322
30EGR1_23403033_ChIP-Seq_LIVER_Mouse1.81739316
31GATA2_21666600_ChIP-Seq_HMVEC_Human1.80682465
32STAT6_21828071_ChIP-Seq_BEAS2B_Human1.80082509
33NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.79341729
34ESR2_21235772_ChIP-Seq_MCF-7_Human1.77283702
35SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.75967668
36CDX2_20551321_ChIP-Seq_CACO-2_Human1.75631438
37GATA1_22025678_ChIP-Seq_K562_Human1.70632611
38VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.66047822
39TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.65090497
40* SOX2_20726797_ChIP-Seq_SW620_Human1.63273211
41SOX2_27498859_Chip-Seq_STOMACH_Mouse1.62902790
42MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.61737206
43BRD4_27068464_Chip-Seq_AML-cells_Mouse1.60080530
44SMAD_19615063_ChIP-ChIP_OVARY_Human1.59693120
45THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.59124617
46PPAR_26484153_Chip-Seq_NCI-H1993_Human1.58610434
47KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.57568968
48CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.54713882
49STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.54699782
50FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.53308786
51GATA4_25053715_ChIP-Seq_YYC3_Human1.52716499
52EGR1_19374776_ChIP-ChIP_THP-1_Human1.46884175
53KDM2B_26808549_Chip-Seq_DND41_Human1.46782100
54KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.46291455
55* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.46031969
56* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.46031969
57FOXO3_23340844_ChIP-Seq_DLD1_Human1.45073968
58NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.40857706
59CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.39657192
60* ELK3_25401928_ChIP-Seq_HUVEC_Human1.39122662
61UTX_26944678_Chip-Seq_JUKART_Human1.32896738
62* GATA6_25053715_ChIP-Seq_YYC3_Human1.32044287
63P63_26484246_Chip-Seq_KERATINOCYTES_Human1.31900391
64* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.31650227
65MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.28935414
66GATA1_19941827_ChIP-Seq_MEL_Mouse1.28826576
67CDX2_19796622_ChIP-Seq_MESCs_Mouse1.27431911
68* RACK7_27058665_Chip-Seq_MCF-7_Human1.26125975
69SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.24190666
70PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.23329761
71FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.21275907
72SPI1_23127762_ChIP-Seq_K562_Human1.18888158
73PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18582454
74MYC_22102868_ChIP-Seq_BL_Human1.17305485
75FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.17218137
76* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.17083806
77KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.16805798
78TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.16023582
79RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.15544937
80GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.15468950
81MAF_26560356_Chip-Seq_TH1_Human1.14906182
82VDR_24763502_ChIP-Seq_THP-1_Human1.14203718
83CJUN_26792858_Chip-Seq_BT549_Human1.13083212
84BCL6_27268052_Chip-Seq_Bcells_Human1.12858133
85VDR_24787735_ChIP-Seq_THP-1_Human1.12829089
86* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.12173476
87MAF_26560356_Chip-Seq_TH2_Human1.11070309
88CTCF_27219007_Chip-Seq_ERYTHROID_Human1.10457540
89CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09904394
90BCOR_27268052_Chip-Seq_Bcells_Human1.09646943
91ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.09519750
92TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.07285876
93JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.07134314
94ATF3_27146783_Chip-Seq_COLON_Human1.06827915
95HIF1A_21447827_ChIP-Seq_MCF-7_Human1.06286596
96KDM2B_26808549_Chip-Seq_K562_Human1.06246611
97FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.05928838
98PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.05913896
99TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.05139487
100HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.04683756
101LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.04677256
102GATA1_22383799_ChIP-Seq_G1ME_Mouse1.03778052
103* MYB_26560356_Chip-Seq_TH2_Human1.03733317
104RUNX1_22412390_ChIP-Seq_EML_Mouse1.03071739
105RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.02960438
106KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.02869657
107TP53_22127205_ChIP-Seq_IMR90_Human1.02699104
108MYB_26560356_Chip-Seq_TH1_Human1.02442619
109* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.02322672
110RUNX_20019798_ChIP-Seq_JUKART_Human1.02198555
111SMC1_22415368_ChIP-Seq_MEFs_Mouse1.02165810
112E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.01820792
113PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.01314726
114KDM2B_26808549_Chip-Seq_JURKAT_Human1.00867122
115SPI1_23547873_ChIP-Seq_NB4_Human0.99932568
116* SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.99737391
117VDR_21846776_ChIP-Seq_THP-1_Human0.99645461
118CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.99199485
119SA1_27219007_Chip-Seq_ERYTHROID_Human0.99069672
120PU_27001747_Chip-Seq_BMDM_Mouse0.98620257
121ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.98065936
122GATA2_19941826_ChIP-Seq_K562_Human0.98054896
123SALL4_18804426_ChIP-ChIP_XEN_Mouse0.97238161
124CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.97008403
125SCL_19346495_ChIP-Seq_HPC-7_Human0.95724469
126SOX9_24532713_ChIP-Seq_HFSC_Mouse0.92781907
127STAT3_1855785_ChIP-Seq_MESCs_Mouse0.92219454
128LXR_22292898_ChIP-Seq_THP-1_Human0.91948270
129GATA1_19941826_ChIP-Seq_K562_Human0.90577153
130TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.89636933
131PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89042657
132TCF7_22412390_ChIP-Seq_EML_Mouse0.88535350
133GATA2_22383799_ChIP-Seq_G1ME_Mouse0.88053059
134TBX20_22328084_ChIP-Seq_HEART_Mouse0.86691961
135TBX20_22080862_ChIP-Seq_HEART_Mouse0.86691961

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009840_abnormal_foam_cell2.64538710
2MP0008438_abnormal_cutaneous_collagen2.34053253
3MP0001835_abnormal_antigen_presentation2.32410841
4MP0003191_abnormal_cellular_cholesterol2.28122256
5MP0003705_abnormal_hypodermis_morpholog2.27526651
6MP0002254_reproductive_system_inflammat2.27373869
7MP0005360_urolithiasis2.26287969
8MP0003436_decreased_susceptibility_to2.25342492
9MP0002138_abnormal_hepatobiliary_system2.21386684
10MP0005058_abnormal_lysosome_morphology2.16817995
11MP0003300_gastrointestinal_ulcer2.08709337
12MP0009785_altered_susceptibility_to2.05717825
13MP0010234_abnormal_vibrissa_follicle1.96877995
14MP0003566_abnormal_cell_adhesion1.95219805
15MP0003724_increased_susceptibility_to1.91438708
16MP0004510_myositis1.91131566
17MP0000685_abnormal_immune_system1.83868166
18MP0004947_skin_inflammation1.78486952
19MP0010155_abnormal_intestine_physiology1.77486480
20MP0005387_immune_system_phenotype1.77357845
21MP0001790_abnormal_immune_system1.77357845
22MP0002419_abnormal_innate_immunity1.73408348
23MP0003303_peritoneal_inflammation1.71572264
24MP0005025_abnormal_response_to1.65623952
25MP0002148_abnormal_hypersensitivity_rea1.65321910
26MP0010352_gastrointestinal_tract_polyps1.63589932
27MP0001873_stomach_inflammation1.63004268
28MP0002139_abnormal_hepatobiliary_system1.59684623
29MP0005451_abnormal_body_composition1.59398493
30MP0006082_CNS_inflammation1.58664854
31MP0001666_abnormal_nutrient_absorption1.55200307
32MP0005275_abnormal_skin_tensile1.54598442
33MP0001533_abnormal_skeleton_physiology1.49182685
34MP0008260_abnormal_autophagy1.48864917
35MP0005000_abnormal_immune_tolerance1.46666819
36MP0003453_abnormal_keratinocyte_physiol1.44472293
37MP0002166_altered_tumor_susceptibility1.42232945
38MP0004264_abnormal_extraembryonic_tissu1.41266495
39MP0002452_abnormal_antigen_presenting1.39678556
40MP0003075_altered_response_to1.36667595
41MP0003252_abnormal_bile_duct1.35711383
42MP0001542_abnormal_bone_strength1.34741719
43MP0005164_abnormal_response_to1.32087323
44MP0005464_abnormal_platelet_physiology1.31980118
45MP0002060_abnormal_skin_morphology1.31638549
46MP0000604_amyloidosis1.31561758
47MP0005365_abnormal_bile_salt1.30911307
48MP0009333_abnormal_splenocyte_physiolog1.29903333
49MP0001800_abnormal_humoral_immune1.29480052
50MP0001845_abnormal_inflammatory_respons1.28743347
51MP0005023_abnormal_wound_healing1.28560624
52MP0003763_abnormal_thymus_physiology1.27335946
53MP0000343_altered_response_to1.26243644
54MP0008875_abnormal_xenobiotic_pharmacok1.24583295
55MP0005166_decreased_susceptibility_to1.24026676
56MP0005085_abnormal_gallbladder_physiolo1.23228506
57MP0009764_decreased_sensitivity_to1.22275058
58MP0002723_abnormal_immune_serum1.21882971
59MP0008469_abnormal_protein_level1.21066971
60MP0005257_abnormal_intraocular_pressure1.19580497
61MP0000465_gastrointestinal_hemorrhage1.19509583
62MP0004858_abnormal_nervous_system1.17348157
63MP0001849_ear_inflammation1.16686072
64MP0003448_altered_tumor_morphology1.16674672
65MP0002877_abnormal_melanocyte_morpholog1.15657981
66MP0004782_abnormal_surfactant_physiolog1.15510737
67MP0001958_emphysema1.15184081
68MP0010329_abnormal_lipoprotein_level1.15180136
69MP0003091_abnormal_cell_migration1.15143629
70MP0003045_fibrosis1.14652512
71MP0003866_abnormal_defecation1.13617788
72MP0009643_abnormal_urine_homeostasis1.12530085
73MP0005310_abnormal_salivary_gland1.12347861
74MP0002998_abnormal_bone_remodeling1.11449279
75MP0002006_tumorigenesis1.11085508
76MP0002405_respiratory_system_inflammati1.10249884
77MP0001819_abnormal_immune_cell1.09049135
78MP0000716_abnormal_immune_system1.08380557
79MP0004883_abnormal_blood_vessel1.08368248
80MP0000609_abnormal_liver_physiology1.07520043
81MP0005670_abnormal_white_adipose1.05587935
82MP0002420_abnormal_adaptive_immunity1.05382478
83MP0004185_abnormal_adipocyte_glucose1.03307897
84MP0005167_abnormal_blood-brain_barrier1.02488918
85MP0000858_altered_metastatic_potential1.00865198
86MP0002933_joint_inflammation1.00813005
87MP0004019_abnormal_vitamin_homeostasis1.00522424
88MP0005671_abnormal_response_to0.98822475
89MP0005083_abnormal_biliary_tract0.98335619
90MP0006054_spinal_hemorrhage0.97419690
91MP0003172_abnormal_lysosome_physiology0.95584264
92MP0002796_impaired_skin_barrier0.94557904
93MP0005666_abnormal_adipose_tissue0.93994672
94MP0003183_abnormal_peptide_metabolism0.93553318
95MP0001663_abnormal_digestive_system0.93347362
96MP0001853_heart_inflammation0.93056614
97MP0009278_abnormal_bone_marrow0.92983183
98MP0002136_abnormal_kidney_physiology0.92561699
99MP0005165_increased_susceptibility_to0.90799655
100MP0003795_abnormal_bone_structure0.90112939
101MP0005076_abnormal_cell_differentiation0.89871104
102MP0000490_abnormal_crypts_of0.89311451
103MP0003329_amyloid_beta_deposits0.89109919
104MP0003828_pulmonary_edema0.88553787
105MP0002398_abnormal_bone_marrow0.87112344
106MP0004272_abnormal_basement_membrane0.86795562
107MP0000249_abnormal_blood_vessel0.84121348
108MP0005319_abnormal_enzyme/_coenzyme0.84097754
109MP0004130_abnormal_muscle_cell0.82962697
110MP0000767_abnormal_smooth_muscle0.82796020
111MP0008004_abnormal_stomach_pH0.82032626
112MP0001851_eye_inflammation0.81983349
113MP0002429_abnormal_blood_cell0.81978167
114MP0005503_abnormal_tendon_morphology0.81828486
115MP0000477_abnormal_intestine_morphology0.81566586
116MP0001216_abnormal_epidermal_layer0.81447833
117MP0002896_abnormal_bone_mineralization0.80748561
118MP0005390_skeleton_phenotype0.80640056
119MP0009763_increased_sensitivity_to0.80261998
120MP0002118_abnormal_lipid_homeostasis0.78498919
121MP0003279_aneurysm0.78100395
122MP0001243_abnormal_dermal_layer0.77837764
123MP0005409_darkened_coat_color0.76647289
124MP0005595_abnormal_vascular_smooth0.76468968
125MP0000678_abnormal_parathyroid_gland0.73125029
126MP0005381_digestive/alimentary_phenotyp0.73009349
127MP0002722_abnormal_immune_system0.72940901

Predicted human phenotypes

RankGene SetZ-score
1Right ventricular cardiomyopathy (HP:0011663)3.98477101
2Eczematoid dermatitis (HP:0000976)3.95729817
3Abnormality of liposaccharide metabolism (HP:0010968)3.59225573
4Abnormality of glycolipid metabolism (HP:0010969)3.59225573
5Myocardial infarction (HP:0001658)3.38009237
6Vacuolated lymphocytes (HP:0001922)3.31598398
7Recurrent abscess formation (HP:0002722)3.27222354
8Systemic lupus erythematosus (HP:0002725)3.16576372
9Autoimmune thrombocytopenia (HP:0001973)3.07961460
10Pustule (HP:0200039)3.05086482
11Recurrent bacterial skin infections (HP:0005406)3.00384033
12Recurrent gram-negative bacterial infections (HP:0005420)2.98375093
13Malnutrition (HP:0004395)2.97723031
14Abnormality of proline metabolism (HP:0010907)2.85891114
15Hydroxyprolinuria (HP:0003080)2.85891114
16Abnormality of macrophages (HP:0004311)2.83948778
17Tetraparesis (HP:0002273)2.74649938
18Esophageal varix (HP:0002040)2.72874945
19Abnormality of glutamine family amino acid metabolism (HP:0010902)2.63910370
20Increased connective tissue (HP:0009025)2.61267215
21Interstitial pulmonary disease (HP:0006530)2.59815153
22Peritonitis (HP:0002586)2.55213559
23Mucopolysacchariduria (HP:0008155)2.53549650
24Urinary glycosaminoglycan excretion (HP:0003541)2.53549650
25Xanthomatosis (HP:0000991)2.50524755
26Gingivitis (HP:0000230)2.48911972
27Atrophic scars (HP:0001075)2.48429057
28Osteolytic defects of the hand bones (HP:0009699)2.45743587
29Osteolytic defects of the phalanges of the hand (HP:0009771)2.45743587
30Dysostosis multiplex (HP:0000943)2.45740703
31Orchitis (HP:0100796)2.45663401
32Premature rupture of membranes (HP:0001788)2.44898483
33Abnormality of mucopolysaccharide metabolism (HP:0011020)2.43887920
34Abnormality of polysaccharide metabolism (HP:0011012)2.43887920
35Abnormality of glycosaminoglycan metabolism (HP:0004371)2.43887920
36Mediastinal lymphadenopathy (HP:0100721)2.39857194
37Nephritis (HP:0000123)2.39266498
38Gastrointestinal infarctions (HP:0005244)2.38107349
39Flat acetabular roof (HP:0003180)2.37904328
40Spondylolisthesis (HP:0003302)2.36971703
41Recurrent fungal infections (HP:0002841)2.35394485
42Glomerulonephritis (HP:0000099)2.35249722
43Hematochezia (HP:0002573)2.34051535
44Emphysema (HP:0002097)2.33484130
45Alopecia of scalp (HP:0002293)2.33435309
46Dilatation of the ascending aorta (HP:0005111)2.31643858
47Myositis (HP:0100614)2.31252436
48Pulmonary infiltrates (HP:0002113)2.30460814
49Vertebral compression fractures (HP:0002953)2.29934418
50Cellulitis (HP:0100658)2.28439226
51Increased cerebral lipofuscin (HP:0011813)2.27658196
52Thin bony cortex (HP:0002753)2.24047551
53Cervical subluxation (HP:0003308)2.23660701
54Ileus (HP:0002595)2.22247056
55Periodontitis (HP:0000704)2.20587584
56Axonal loss (HP:0003447)2.19771270
57Gingival bleeding (HP:0000225)2.19154790
58Chronic otitis media (HP:0000389)2.16012374
59Vascular tortuosity (HP:0004948)2.14561153
60Distal lower limb muscle weakness (HP:0009053)2.13146786
61Increased IgE level (HP:0003212)2.13037707
62Cerebral aneurysm (HP:0004944)2.12966281
63Prostate neoplasm (HP:0100787)2.12796693
64Abdominal distention (HP:0003270)2.11111223
65Elevated erythrocyte sedimentation rate (HP:0003565)2.11067378
66Complement deficiency (HP:0004431)2.07953237
67Joint stiffness (HP:0001387)2.06511081
68Hemoptysis (HP:0002105)2.06162782
69Ventricular tachycardia (HP:0004756)2.05254380
70Thick nail (HP:0001805)2.04623658
71Chronic obstructive pulmonary disease (HP:0006510)2.04501543
72Obstructive lung disease (HP:0006536)2.04501543
73Abnormality of complement system (HP:0005339)2.03116976
74Recurrent skin infections (HP:0001581)2.02376656
75Purpura (HP:0000979)2.01542100
76Polycythemia (HP:0001901)1.99913448
77Aneurysm (HP:0002617)1.99377265
78Arterial tortuosity (HP:0005116)1.98758352
79Abnormality of the nasal mucosa (HP:0000433)1.98092740
80Hypoalphalipoproteinemia (HP:0003233)1.96047997
81Stomatitis (HP:0010280)1.94844813
82Gastrointestinal stroma tumor (HP:0100723)1.93787343
83Loss of speech (HP:0002371)1.92548345
84Meningitis (HP:0001287)1.92087803
85Aortic dissection (HP:0002647)1.91946262
86Arterial thrombosis (HP:0004420)1.91744927
87Spontaneous hematomas (HP:0007420)1.91712431
88Colitis (HP:0002583)1.91202029
89Intrahepatic cholestasis (HP:0001406)1.87991076
90Urticaria (HP:0001025)1.87699837
91Abnormal delayed hypersensitivity skin test (HP:0002963)1.87471898
92Amyloidosis (HP:0011034)1.86906006
93Fragile skin (HP:0001030)1.86088207
94Abnormality of monocarboxylic acid metabolism (HP:0010996)1.85501281
95Increased neuronal autofluorescent lipopigment (HP:0002074)1.84546732
96Aortic aneurysm (HP:0004942)1.83929977
97Ankle contracture (HP:0006466)1.83495915
98Keratoconjunctivitis sicca (HP:0001097)1.83074417
99Chronic diarrhea (HP:0002028)1.83041920
100Hemorrhage of the eye (HP:0011885)1.82540324
101Distal upper limb amyotrophy (HP:0007149)1.81844202
102Upper limb amyotrophy (HP:0009129)1.81844202
103Mildly elevated creatine phosphokinase (HP:0008180)1.80881845
104Blue sclerae (HP:0000592)1.80569930
105Asymmetric septal hypertrophy (HP:0001670)1.79832515
106Joint hemorrhage (HP:0005261)1.79713116
107Hypoglycemic coma (HP:0001325)1.79547167
108Distal lower limb amyotrophy (HP:0008944)1.78899904
109Cupped ribs (HP:0000887)1.78338429
110Recurrent viral infections (HP:0004429)1.77345575
111Frequent falls (HP:0002359)1.77297056
112Optic neuritis (HP:0100653)1.76991732
113Retrobulbar optic neuritis (HP:0100654)1.76991732
114Broad face (HP:0000283)1.76531742
115Vasculitis (HP:0002633)1.75422556
116Abnormality of the pericardium (HP:0001697)1.75198986
117Protrusio acetabuli (HP:0003179)1.75103501
118Epistaxis (HP:0000421)1.74896380
119Wormian bones (HP:0002645)1.74489348
120Facial diplegia (HP:0001349)1.74271136
121Deep venous thrombosis (HP:0002625)1.74110635
122Inflammation of the large intestine (HP:0002037)1.73683386
123Ovoid vertebral bodies (HP:0003300)1.73344521
124Restrictive lung disease (HP:0002091)1.73315816
125Polygenic inheritance (HP:0010982)1.73254251
126Hypergammaglobulinemia (HP:0010702)1.72321927
127Abnormal platelet volume (HP:0011876)1.70450048
128Nasal polyposis (HP:0100582)1.69747770
129Increased mean platelet volume (HP:0011877)1.69004128
130Bone pain (HP:0002653)1.68747215
131Type 1 muscle fiber predominance (HP:0003803)1.68230534
132Petechiae (HP:0000967)1.68211338
133Milia (HP:0001056)1.68050579
134Premature loss of primary teeth (HP:0006323)1.65831284
135Increased serum ferritin (HP:0003281)1.65676667
136Menorrhagia (HP:0000132)1.65080687
137Abnormality of glycosphingolipid metabolism (HP:0004343)1.65000338

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN13.17047011
2MAP3K142.95447130
3MST1R2.61544070
4TBK12.56760392
5TYK22.55728504
6PRPF4B2.41629783
7EPHB12.41185821
8IRAK32.36516590
9TTN2.30717749
10TRIB32.11965341
11FGFR42.09422981
12EPHA22.06975376
13JAK31.96333373
14PTK61.88131888
15JAK11.86005918
16BLK1.79503726
17EPHA31.77712473
18IKBKE1.73586974
19TAOK31.72330535
20FRK1.66289340
21PRKD21.65396772
22MST41.63238542
23MAP3K31.62130547
24IKBKB1.57719495
25CDC42BPA1.56963414
26RIPK11.56302657
27KIT1.55564031
28MAP3K111.54841111
29TGFBR21.54657975
30PIK3CA1.54552826
31SIK11.43130593
32MAP4K11.41511296
33MAP2K21.41264176
34TAOK21.36361199
35CSK1.35642127
36IRAK41.30896615
37CHUK1.29607150
38TAOK11.25240605
39MAP2K31.24112470
40PRKG21.22127409
41MET1.19959911
42PIK3CG1.18903243
43NEK91.16068204
44SMG11.13437739
45CAMK1D1.11771518
46PKN21.11683567
47STK101.09204075
48TESK21.07999197
49KDR1.05299542
50PIM21.04601103
51BMX1.03252863
52MAP3K131.02220714
53FES1.00705163
54RPS6KA40.99814078
55FLT30.99806666
56TRPM70.98737978
57LMTK20.98537078
58MYLK0.97203991
59LRRK20.96520363
60PTK20.96263007
61ZAP700.95197305
62RIPK40.93845466
63FGFR30.90424326
64PDPK10.89575823
65MAP3K60.87057332
66INSRR0.85847599
67JAK20.85178408
68GRK70.83820761
69EPHB20.83276596
70PRKAA20.82857543
71MOS0.82166563
72MATK0.81826057
73CSF1R0.81779318
74PAK40.81365721
75MARK20.81355813
76DDR20.79925186
77NME20.78865662
78TIE10.78274109
79ICK0.76798183
80SYK0.76732734
81PTK2B0.75439738
82PDGFRA0.74562711
83TNK20.74458135
84FER0.73217043
85TXK0.73184516
86MAPK70.71345072
87RPS6KA20.70175830
88STK380.69445879
89LYN0.69031821
90HIPK20.68990844
91MAP2K10.68004445
92MAP3K100.67707229
93PIM10.66361645
94MAPKAPK30.65591230
95LATS10.65553062
96HCK0.64864206
97PDK10.62988744
98KSR20.62344432
99NLK0.61896561
100BTK0.60436075
101MAP3K10.60049573
102DMPK0.56865589
103FGR0.56501948
104TEC0.55997321
105MAPKAPK20.55410987
106LCK0.55238912
107IRAK10.54934868
108NUAK10.53307659
109MAP3K20.53220442
110MAPK110.53148676
111MAP2K60.51032104
112SIK30.50550775
113ITK0.50480751
114PDGFRB0.50174634
115RPS6KL10.49422212
116RPS6KC10.49422212
117DYRK1B0.48539396
118STK30.48488423
119PBK0.47180910
120ACVR1B0.46860309
121ABL10.46827275
122FYN0.46744147
123GRK60.45814503
124TESK10.44373385
125BCKDK0.43932549
126ABL20.43750639
127MAP3K70.42234231
128GSK3A0.42079182
129EGFR0.41389792
130OBSCN0.40933193
131MAP3K80.40630972
132MARK30.38092650
133CDK60.37956913
134CDK120.36698671

Predicted pathways (KEGG)

RankGene SetZ-score
1Caffeine metabolism_Homo sapiens_hsa002322.49591560
2Staphylococcus aureus infection_Homo sapiens_hsa051502.30053310
3Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.11863892
4Leishmaniasis_Homo sapiens_hsa051402.08737025
5Autoimmune thyroid disease_Homo sapiens_hsa053201.83590440
6NF-kappa B signaling pathway_Homo sapiens_hsa040641.80596264
7Other glycan degradation_Homo sapiens_hsa005111.75056912
8Sulfur metabolism_Homo sapiens_hsa009201.72170648
9Fat digestion and absorption_Homo sapiens_hsa049751.71103900
10Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.62688683
11Glycosaminoglycan degradation_Homo sapiens_hsa005311.61513805
12Osteoclast differentiation_Homo sapiens_hsa043801.56639751
13Lysosome_Homo sapiens_hsa041421.55419717
14Toll-like receptor signaling pathway_Homo sapiens_hsa046201.52415086
15Pentose and glucuronate interconversions_Homo sapiens_hsa000401.51777052
16Toxoplasmosis_Homo sapiens_hsa051451.49437131
17Complement and coagulation cascades_Homo sapiens_hsa046101.45143469
18Mineral absorption_Homo sapiens_hsa049781.44920964
19Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.44562018
20Pertussis_Homo sapiens_hsa051331.43938539
21PPAR signaling pathway_Homo sapiens_hsa033201.43244445
22Malaria_Homo sapiens_hsa051441.42295170
23Histidine metabolism_Homo sapiens_hsa003401.39808376
24Legionellosis_Homo sapiens_hsa051341.39552489
25TNF signaling pathway_Homo sapiens_hsa046681.38142632
26Asthma_Homo sapiens_hsa053101.37373627
27Vitamin digestion and absorption_Homo sapiens_hsa049771.30801794
28Tryptophan metabolism_Homo sapiens_hsa003801.29551701
29RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.29080919
30Intestinal immune network for IgA production_Homo sapiens_hsa046721.28836477
31Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.25618093
32Type I diabetes mellitus_Homo sapiens_hsa049401.25007427
33Fatty acid degradation_Homo sapiens_hsa000711.24799574
34Starch and sucrose metabolism_Homo sapiens_hsa005001.24426502
35Measles_Homo sapiens_hsa051621.20339312
36Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.20285827
37Renin-angiotensin system_Homo sapiens_hsa046141.18019683
38Apoptosis_Homo sapiens_hsa042101.17978326
39Leukocyte transendothelial migration_Homo sapiens_hsa046701.17751929
40Tuberculosis_Homo sapiens_hsa051521.17713839
41NOD-like receptor signaling pathway_Homo sapiens_hsa046211.15759504
42Influenza A_Homo sapiens_hsa051641.14908555
43Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.14129475
44Amoebiasis_Homo sapiens_hsa051461.12177136
45ABC transporters_Homo sapiens_hsa020101.07425609
46Hepatitis C_Homo sapiens_hsa051601.07286112
47Primary immunodeficiency_Homo sapiens_hsa053401.06447345
48Chemokine signaling pathway_Homo sapiens_hsa040621.05690378
49ECM-receptor interaction_Homo sapiens_hsa045121.04871999
50Cyanoamino acid metabolism_Homo sapiens_hsa004601.03575362
51Galactose metabolism_Homo sapiens_hsa000521.01213505
52Antigen processing and presentation_Homo sapiens_hsa046121.01026043
53Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.00161000
54Small cell lung cancer_Homo sapiens_hsa052220.99519752
55Salmonella infection_Homo sapiens_hsa051320.98327745
56Jak-STAT signaling pathway_Homo sapiens_hsa046300.97833614
57Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.95478372
58Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.95042330
59Adipocytokine signaling pathway_Homo sapiens_hsa049200.89580623
60Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.89144782
61AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.88272478
62Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.86231181
63T cell receptor signaling pathway_Homo sapiens_hsa046600.86071660
64Hematopoietic cell lineage_Homo sapiens_hsa046400.85476487
65Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.84985034
66Shigellosis_Homo sapiens_hsa051310.84370987
67Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.84317513
68Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.84018003
69Insulin resistance_Homo sapiens_hsa049310.83795065
70Arginine biosynthesis_Homo sapiens_hsa002200.83738283
71Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.83214130
72Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.82886507
73Bladder cancer_Homo sapiens_hsa052190.82308252
74Maturity onset diabetes of the young_Homo sapiens_hsa049500.81158322
75B cell receptor signaling pathway_Homo sapiens_hsa046620.79641913
76Fructose and mannose metabolism_Homo sapiens_hsa000510.78386953
77Endocytosis_Homo sapiens_hsa041440.77811758
78beta-Alanine metabolism_Homo sapiens_hsa004100.76929872
79Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.76814163
80Protein digestion and absorption_Homo sapiens_hsa049740.76630230
81Acute myeloid leukemia_Homo sapiens_hsa052210.76591389
82Folate biosynthesis_Homo sapiens_hsa007900.76294645
83Focal adhesion_Homo sapiens_hsa045100.76034108
84Phenylalanine metabolism_Homo sapiens_hsa003600.75977175
85Phagosome_Homo sapiens_hsa041450.75677982
86Chemical carcinogenesis_Homo sapiens_hsa052040.74173766
87Primary bile acid biosynthesis_Homo sapiens_hsa001200.74163603
88VEGF signaling pathway_Homo sapiens_hsa043700.74062117
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.73205751
90Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.73071282
91Bile secretion_Homo sapiens_hsa049760.72773578
92Graft-versus-host disease_Homo sapiens_hsa053320.72645087
93Viral myocarditis_Homo sapiens_hsa054160.72640666
94Platelet activation_Homo sapiens_hsa046110.71059854
95Adherens junction_Homo sapiens_hsa045200.70254268
96Notch signaling pathway_Homo sapiens_hsa043300.69906931
97Pancreatic cancer_Homo sapiens_hsa052120.68600039
98Prion diseases_Homo sapiens_hsa050200.68075805
99Allograft rejection_Homo sapiens_hsa053300.67230677
100Herpes simplex infection_Homo sapiens_hsa051680.66373239
101Peroxisome_Homo sapiens_hsa041460.66195059
102Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.64532759
103Rheumatoid arthritis_Homo sapiens_hsa053230.64486484
104alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.64428375
105Sphingolipid metabolism_Homo sapiens_hsa006000.62897285
106Phospholipase D signaling pathway_Homo sapiens_hsa040720.62323323
107African trypanosomiasis_Homo sapiens_hsa051430.61953216
108Selenocompound metabolism_Homo sapiens_hsa004500.58716718
109Regulation of actin cytoskeleton_Homo sapiens_hsa048100.58067823
110Chronic myeloid leukemia_Homo sapiens_hsa052200.57645307
111Sphingolipid signaling pathway_Homo sapiens_hsa040710.57019843
112Neurotrophin signaling pathway_Homo sapiens_hsa047220.56723004
113Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.56276482
114Fatty acid metabolism_Homo sapiens_hsa012120.55517510
115Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.55025552
116GnRH signaling pathway_Homo sapiens_hsa049120.54675408
117Proteoglycans in cancer_Homo sapiens_hsa052050.54529740
118Sulfur relay system_Homo sapiens_hsa041220.53580298
119Arachidonic acid metabolism_Homo sapiens_hsa005900.52716635
120Retinol metabolism_Homo sapiens_hsa008300.52658092
121Hepatitis B_Homo sapiens_hsa051610.52523392
122Glycerolipid metabolism_Homo sapiens_hsa005610.51931193
123Prolactin signaling pathway_Homo sapiens_hsa049170.51410540
124Linoleic acid metabolism_Homo sapiens_hsa005910.49770475
125Non-small cell lung cancer_Homo sapiens_hsa052230.48671581
126Carbohydrate digestion and absorption_Homo sapiens_hsa049730.46608404
127Renal cell carcinoma_Homo sapiens_hsa052110.42471767
128HTLV-I infection_Homo sapiens_hsa051660.40958961

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »