

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cell migration involved in heart development (GO:0060973) | 6.94452426 |
| 2 | kidney mesenchyme development (GO:0072074) | 6.37052237 |
| 3 | collagen fibril organization (GO:0030199) | 6.29525904 |
| 4 | protein heterotrimerization (GO:0070208) | 5.80853007 |
| 5 | metanephric mesenchyme development (GO:0072075) | 5.40298655 |
| 6 | dermatan sulfate biosynthetic process (GO:0030208) | 4.99153442 |
| 7 | bone trabecula formation (GO:0060346) | 4.96379720 |
| 8 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 4.81601228 |
| 9 | tooth mineralization (GO:0034505) | 4.70772195 |
| 10 | mesenchymal-epithelial cell signaling (GO:0060638) | 4.69632222 |
| 11 | dermatan sulfate metabolic process (GO:0030205) | 4.66966301 |
| 12 | skin morphogenesis (GO:0043589) | 4.56080364 |
| 13 | extracellular fibril organization (GO:0043206) | 4.34364649 |
| 14 | keratan sulfate catabolic process (GO:0042340) | 4.34182874 |
| 15 | collagen catabolic process (GO:0030574) | 4.20890236 |
| 16 | sequestering of extracellular ligand from receptor (GO:0035581) | 4.19369551 |
| 17 | collagen metabolic process (GO:0032963) | 4.16183089 |
| 18 | chondrocyte proliferation (GO:0035988) | 4.04694415 |
| 19 | atrioventricular valve morphogenesis (GO:0003181) | 4.03474344 |
| 20 | pericardium development (GO:0060039) | 4.01876032 |
| 21 | endocardial cushion development (GO:0003197) | 4.01412669 |
| 22 | basement membrane organization (GO:0071711) | 3.95726784 |
| 23 | glomerular basement membrane development (GO:0032836) | 3.95613884 |
| 24 | axon extension involved in axon guidance (GO:0048846) | 3.91383296 |
| 25 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.91383296 |
| 26 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 3.89207530 |
| 27 | multicellular organismal macromolecule metabolic process (GO:0044259) | 3.88340022 |
| 28 | multicellular organismal catabolic process (GO:0044243) | 3.85892845 |
| 29 | craniofacial suture morphogenesis (GO:0097094) | 3.78255838 |
| 30 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 3.75914988 |
| 31 | endodermal cell differentiation (GO:0035987) | 3.72325382 |
| 32 | multicellular organismal metabolic process (GO:0044236) | 3.70020601 |
| 33 | cell proliferation involved in metanephros development (GO:0072203) | 3.66493992 |
| 34 | embryonic cranial skeleton morphogenesis (GO:0048701) | 3.65873297 |
| 35 | middle ear morphogenesis (GO:0042474) | 3.64656189 |
| 36 | establishment of planar polarity (GO:0001736) | 3.61283541 |
| 37 | establishment of tissue polarity (GO:0007164) | 3.61283541 |
| 38 | extracellular matrix assembly (GO:0085029) | 3.60852739 |
| 39 | extracellular matrix disassembly (GO:0022617) | 3.58650772 |
| 40 | positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568) | 3.58494240 |
| 41 | fibril organization (GO:0097435) | 3.52497933 |
| 42 | dopaminergic neuron differentiation (GO:0071542) | 3.52206216 |
| 43 | vascular endothelial growth factor signaling pathway (GO:0038084) | 3.47945329 |
| 44 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.45102711 |
| 45 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 3.43515577 |
| 46 | endocardial cushion morphogenesis (GO:0003203) | 3.31173294 |
| 47 | cranial suture morphogenesis (GO:0060363) | 3.29903415 |
| 48 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.27719655 |
| 49 | positive regulation of catenin import into nucleus (GO:0035413) | 3.25860835 |
| 50 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.22274307 |
| 51 | positive regulation of gastrulation (GO:2000543) | 3.20862428 |
| 52 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.12169716 |
| 53 | positive regulation of axon extension (GO:0045773) | 3.11796874 |
| 54 | face morphogenesis (GO:0060325) | 3.11780726 |
| 55 | cardiac epithelial to mesenchymal transition (GO:0060317) | 3.08212589 |
| 56 | negative regulation of axon guidance (GO:1902668) | 3.05884517 |
| 57 | type B pancreatic cell proliferation (GO:0044342) | 3.05805110 |
| 58 | mesenchyme morphogenesis (GO:0072132) | 3.04715591 |
| 59 | embryonic forelimb morphogenesis (GO:0035115) | 3.04250113 |
| 60 | smooth muscle tissue development (GO:0048745) | 3.03501711 |
| 61 | cell proliferation involved in kidney development (GO:0072111) | 3.02539168 |
| 62 | extracellular matrix organization (GO:0030198) | 3.00882121 |
| 63 | extracellular structure organization (GO:0043062) | 2.99757311 |
| 64 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 2.99622389 |
| 65 | negative regulation of cartilage development (GO:0061037) | 2.98174874 |
| 66 | chondroitin sulfate catabolic process (GO:0030207) | 2.96942819 |
| 67 | organ induction (GO:0001759) | 2.93399346 |
| 68 | lymph vessel development (GO:0001945) | 2.92642461 |
| 69 | regulation of organ formation (GO:0003156) | 2.91996749 |
| 70 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.90524217 |
| 71 | positive regulation of epithelial to mesenchymal transition (GO:0010718) | 2.90331341 |
| 72 | extracellular regulation of signal transduction (GO:1900115) | 2.87069611 |
| 73 | extracellular negative regulation of signal transduction (GO:1900116) | 2.87069611 |
| 74 | regulation of histone phosphorylation (GO:0033127) | 2.86333710 |
| 75 | growth hormone secretion (GO:0030252) | 2.82517433 |
| 76 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.82153231 |
| 77 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 2.81777263 |
| 78 | muscle cell migration (GO:0014812) | 2.80458933 |
| 79 | blood vessel maturation (GO:0001955) | 2.77926247 |
| 80 | positive regulation of actin filament depolymerization (GO:0030836) | 2.77857731 |
| 81 | negative regulation of fatty acid transport (GO:2000192) | 2.77807236 |
| 82 | adhesion of symbiont to host cell (GO:0044650) | 2.76047368 |
| 83 | virion attachment to host cell (GO:0019062) | 2.76047368 |
| 84 | sulfur compound catabolic process (GO:0044273) | 2.74845213 |
| 85 | chondrocyte development (GO:0002063) | 2.72586859 |
| 86 | regulation of extracellular matrix disassembly (GO:0010715) | 2.72195008 |
| 87 | regulation of SMAD protein import into nucleus (GO:0060390) | 2.70783363 |
| 88 | negative regulation of smooth muscle cell migration (GO:0014912) | 2.69406114 |
| 89 | vasculature development (GO:0001944) | 2.68631284 |
| 90 | forelimb morphogenesis (GO:0035136) | 2.68552449 |
| 91 | outer ear morphogenesis (GO:0042473) | 2.67886098 |
| 92 | positive regulation of osteoblast proliferation (GO:0033690) | 2.65421402 |
| 93 | regulation of axon guidance (GO:1902667) | 2.65022821 |
| 94 | non-canonical Wnt signaling pathway (GO:0035567) | 2.64559336 |
| 95 | regulation of collagen metabolic process (GO:0010712) | 2.62101470 |
| 96 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.62079422 |
| 97 | regulation of chondrocyte differentiation (GO:0032330) | 2.61658319 |
| 98 | cellular response to vitamin (GO:0071295) | 2.60819270 |
| 99 | head development (GO:0060322) | 2.57869470 |
| 100 | cellular response to amino acid stimulus (GO:0071230) | 2.57805735 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 5.27391357 |
| 2 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 5.16045609 |
| 3 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 4.04815227 |
| 4 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.82450857 |
| 5 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.76307194 |
| 6 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.60790836 |
| 7 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.52892392 |
| 8 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 2.51806256 |
| 9 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.36921468 |
| 10 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.32869059 |
| 11 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.32869059 |
| 12 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.32766745 |
| 13 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.22444166 |
| 14 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 2.15596588 |
| 15 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.15274212 |
| 16 | CJUN_26792858_Chip-Seq_BT549_Human | 2.13309535 |
| 17 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 2.11648573 |
| 18 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.07959451 |
| 19 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 2.05476735 |
| 20 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.03531930 |
| 21 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.98806102 |
| 22 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.92059750 |
| 23 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.90611452 |
| 24 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.90481639 |
| 25 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.87812772 |
| 26 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.84791640 |
| 27 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.84030753 |
| 28 | VDR_22108803_ChIP-Seq_LS180_Human | 1.80231755 |
| 29 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.79592954 |
| 30 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.78956492 |
| 31 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.78532828 |
| 32 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.77960834 |
| 33 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.77904709 |
| 34 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.76991169 |
| 35 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.76422557 |
| 36 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.74191092 |
| 37 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.71479772 |
| 38 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.66769273 |
| 39 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.65857474 |
| 40 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.62072168 |
| 41 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.59246280 |
| 42 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.57271883 |
| 43 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.56244751 |
| 44 | TP53_16413492_ChIP-PET_HCT116_Human | 1.53398628 |
| 45 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.50076659 |
| 46 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.47773658 |
| 47 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.46609045 |
| 48 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.46597697 |
| 49 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.43411527 |
| 50 | SA1_22415368_ChIP-Seq_MEFs_Mouse | 1.42913432 |
| 51 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.42389956 |
| 52 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.38162818 |
| 53 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.35800227 |
| 54 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.33215778 |
| 55 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.30194867 |
| 56 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.27855843 |
| 57 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.24665523 |
| 58 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.20912365 |
| 59 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.19568498 |
| 60 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.19568498 |
| 61 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.17084270 |
| 62 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.16204555 |
| 63 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.13553430 |
| 64 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.13449797 |
| 65 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.12675801 |
| 66 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.09350427 |
| 67 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.07870299 |
| 68 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.05990517 |
| 69 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.03925025 |
| 70 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.01534791 |
| 71 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.00239249 |
| 72 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.99557992 |
| 73 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.99451641 |
| 74 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.98959504 |
| 75 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.98745048 |
| 76 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.98688707 |
| 77 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.97174479 |
| 78 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.95905705 |
| 79 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.95105630 |
| 80 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.94244960 |
| 81 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.91917728 |
| 82 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.91238469 |
| 83 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.90382906 |
| 84 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.90335181 |
| 85 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.90185822 |
| 86 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.90172111 |
| 87 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.89696772 |
| 88 | RXR_22108803_ChIP-Seq_LS180_Human | 0.89435567 |
| 89 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.88999957 |
| 90 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.88849581 |
| 91 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.87808605 |
| 92 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.87495339 |
| 93 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.86705873 |
| 94 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.85787203 |
| 95 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.84106956 |
| 96 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.83228762 |
| 97 | P300_19829295_ChIP-Seq_ESCs_Human | 0.83058617 |
| 98 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.82872395 |
| 99 | AR_25329375_ChIP-Seq_VCAP_Human | 0.82610145 |
| 100 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.82442680 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008438_abnormal_cutaneous_collagen | 8.03980308 |
| 2 | MP0005503_abnormal_tendon_morphology | 7.46564258 |
| 3 | MP0005275_abnormal_skin_tensile | 5.68804032 |
| 4 | MP0003279_aneurysm | 3.96178454 |
| 5 | MP0003705_abnormal_hypodermis_morpholog | 3.22681249 |
| 6 | MP0004272_abnormal_basement_membrane | 3.13763760 |
| 7 | MP0009384_cardiac_valve_regurgitation | 2.95750113 |
| 8 | MP0003283_abnormal_digestive_organ | 2.95743600 |
| 9 | MP0005257_abnormal_intraocular_pressure | 2.86188144 |
| 10 | MP0001542_abnormal_bone_strength | 2.80132268 |
| 11 | MP0001958_emphysema | 2.78975781 |
| 12 | MP0005508_abnormal_skeleton_morphology | 2.69746090 |
| 13 | MP0006054_spinal_hemorrhage | 2.63649404 |
| 14 | MP0010030_abnormal_orbit_morphology | 2.43467534 |
| 15 | MP0009250_abnormal_appendicular_skeleto | 2.38332390 |
| 16 | MP0002295_abnormal_pulmonary_circulatio | 2.37308595 |
| 17 | MP0002108_abnormal_muscle_morphology | 2.26074904 |
| 18 | MP0008004_abnormal_stomach_pH | 1.91268833 |
| 19 | MP0002060_abnormal_skin_morphology | 1.84101782 |
| 20 | MP0001243_abnormal_dermal_layer | 1.75196174 |
| 21 | MP0005023_abnormal_wound_healing | 1.72328288 |
| 22 | MP0000566_synostosis | 1.70465406 |
| 23 | MP0000767_abnormal_smooth_muscle | 1.57087771 |
| 24 | MP0000751_myopathy | 1.50885106 |
| 25 | MP0005390_skeleton_phenotype | 1.50867968 |
| 26 | MP0009053_abnormal_anal_canal | 1.40899132 |
| 27 | MP0001299_abnormal_eye_distance/ | 1.36767884 |
| 28 | MP0000534_abnormal_ureter_morphology | 1.33850939 |
| 29 | MP0000462_abnormal_digestive_system | 1.31383366 |
| 30 | MP0010368_abnormal_lymphatic_system | 1.30309370 |
| 31 | MP0002282_abnormal_trachea_morphology | 1.28641650 |
| 32 | MP0004134_abnormal_chest_morphology | 1.27588936 |
| 33 | MP0000049_abnormal_middle_ear | 1.24895979 |
| 34 | MP0002896_abnormal_bone_mineralization | 1.19722307 |
| 35 | MP0002938_white_spotting | 1.19359991 |
| 36 | MP0000163_abnormal_cartilage_morphology | 1.19049327 |
| 37 | MP0002115_abnormal_skeleton_extremities | 1.17322205 |
| 38 | MP0005623_abnormal_meninges_morphology | 1.17219351 |
| 39 | MP0003950_abnormal_plasma_membrane | 1.15950993 |
| 40 | MP0003937_abnormal_limbs/digits/tail_de | 1.15011574 |
| 41 | MP0003091_abnormal_cell_migration | 1.14358461 |
| 42 | MP0002254_reproductive_system_inflammat | 1.11329525 |
| 43 | MP0005171_absent_coat_pigmentation | 1.07237300 |
| 44 | MP0002933_joint_inflammation | 1.07206182 |
| 45 | MP0002102_abnormal_ear_morphology | 1.06172754 |
| 46 | MP0003941_abnormal_skin_development | 1.04922895 |
| 47 | MP0000538_abnormal_urinary_bladder | 1.04120214 |
| 48 | MP0000762_abnormal_tongue_morphology | 1.03401936 |
| 49 | MP0005595_abnormal_vascular_smooth | 1.03292357 |
| 50 | MP0000749_muscle_degeneration | 0.97476901 |
| 51 | MP0000013_abnormal_adipose_tissue | 0.96614125 |
| 52 | MP0005165_increased_susceptibility_to | 0.95421325 |
| 53 | MP0005367_renal/urinary_system_phenotyp | 0.94526688 |
| 54 | MP0000516_abnormal_urinary_system | 0.94526688 |
| 55 | MP0000428_abnormal_craniofacial_morphol | 0.94129328 |
| 56 | MP0003942_abnormal_urinary_system | 0.91488575 |
| 57 | MP0002233_abnormal_nose_morphology | 0.90688672 |
| 58 | MP0003385_abnormal_body_wall | 0.86310592 |
| 59 | MP0010386_abnormal_urinary_bladder | 0.85154158 |
| 60 | MP0003755_abnormal_palate_morphology | 0.84841358 |
| 61 | MP0002113_abnormal_skeleton_development | 0.83110553 |
| 62 | MP0001879_abnormal_lymphatic_vessel | 0.80227789 |
| 63 | MP0002116_abnormal_craniofacial_bone | 0.79875443 |
| 64 | MP0005164_abnormal_response_to | 0.79761027 |
| 65 | MP0000432_abnormal_head_morphology | 0.78786133 |
| 66 | MP0003935_abnormal_craniofacial_develop | 0.78506131 |
| 67 | MP0002109_abnormal_limb_morphology | 0.78218012 |
| 68 | MP0000537_abnormal_urethra_morphology | 0.75991284 |
| 69 | MP0003115_abnormal_respiratory_system | 0.71797279 |
| 70 | MP0002114_abnormal_axial_skeleton | 0.70457170 |
| 71 | MP0009780_abnormal_chondrocyte_physiolo | 0.67825590 |
| 72 | MP0002128_abnormal_blood_circulation | 0.63994795 |
| 73 | MP0004858_abnormal_nervous_system | 0.63798434 |
| 74 | MP0002249_abnormal_larynx_morphology | 0.61616637 |
| 75 | MP0010352_gastrointestinal_tract_polyps | 0.60544669 |
| 76 | MP0001270_distended_abdomen | 0.59643387 |
| 77 | MP0005369_muscle_phenotype | 0.59579576 |
| 78 | MP0003448_altered_tumor_morphology | 0.57679714 |
| 79 | MP0005187_abnormal_penis_morphology | 0.57467382 |
| 80 | MP0002168_other_aberrant_phenotype | 0.57369628 |
| 81 | MP0004883_abnormal_blood_vessel | 0.57158473 |
| 82 | MP0002133_abnormal_respiratory_system | 0.56269354 |
| 83 | MP0005388_respiratory_system_phenotype | 0.56269354 |
| 84 | MP0002932_abnormal_joint_morphology | 0.55895721 |
| 85 | MP0003566_abnormal_cell_adhesion | 0.54123380 |
| 86 | MP0003186_abnormal_redox_activity | 0.52902168 |
| 87 | MP0001348_abnormal_lacrimal_gland | 0.52755687 |
| 88 | MP0002111_abnormal_tail_morphology | 0.52533844 |
| 89 | MP0003795_abnormal_bone_structure | 0.52452016 |
| 90 | MP0003638_abnormal_response/metabolism_ | 0.49811348 |
| 91 | MP0000026_abnormal_inner_ear | 0.46362827 |
| 92 | MP0008260_abnormal_autophagy | 0.46237930 |
| 93 | MP0000230_abnormal_systemic_arterial | 0.46192681 |
| 94 | MP0001614_abnormal_blood_vessel | 0.45966156 |
| 95 | MP0001533_abnormal_skeleton_physiology | 0.45842865 |
| 96 | MP0002876_abnormal_thyroid_physiology | 0.45779937 |
| 97 | MP0001175_abnormal_lung_morphology | 0.45248272 |
| 98 | MP0003119_abnormal_digestive_system | 0.44409669 |
| 99 | MP0000759_abnormal_skeletal_muscle | 0.43378183 |
| 100 | MP0000604_amyloidosis | 0.43332298 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Premature rupture of membranes (HP:0001788) | 7.33450993 |
| 2 | Protrusio acetabuli (HP:0003179) | 6.76365516 |
| 3 | Soft skin (HP:0000977) | 5.25063808 |
| 4 | Aortic dissection (HP:0002647) | 4.96988606 |
| 5 | Ankle contracture (HP:0006466) | 4.61229786 |
| 6 | Bladder diverticulum (HP:0000015) | 4.45992284 |
| 7 | Follicular hyperkeratosis (HP:0007502) | 4.44246611 |
| 8 | Vascular tortuosity (HP:0004948) | 4.31091152 |
| 9 | Abnormality of dentin (HP:0010299) | 4.19129592 |
| 10 | Aortic aneurysm (HP:0004942) | 4.18088863 |
| 11 | Broad metatarsal (HP:0001783) | 4.11317919 |
| 12 | Atrophic scars (HP:0001075) | 4.08146880 |
| 13 | Spondylolisthesis (HP:0003302) | 4.01401080 |
| 14 | Neonatal short-limb short stature (HP:0008921) | 3.96592268 |
| 15 | Wrist flexion contracture (HP:0001239) | 3.90514290 |
| 16 | Genu recurvatum (HP:0002816) | 3.70160203 |
| 17 | Fragile skin (HP:0001030) | 3.57763750 |
| 18 | Peritonitis (HP:0002586) | 3.56931013 |
| 19 | Arterial tortuosity (HP:0005116) | 3.54246399 |
| 20 | Type 1 muscle fiber predominance (HP:0003803) | 3.45403896 |
| 21 | Wormian bones (HP:0002645) | 3.34848879 |
| 22 | Blue sclerae (HP:0000592) | 3.30436536 |
| 23 | Bowel diverticulosis (HP:0005222) | 3.26751917 |
| 24 | Slender build (HP:0001533) | 3.18179789 |
| 25 | Wide anterior fontanel (HP:0000260) | 3.08921104 |
| 26 | Hypoplastic ischia (HP:0003175) | 3.07900225 |
| 27 | Absent frontal sinuses (HP:0002688) | 3.07608674 |
| 28 | Shallow orbits (HP:0000586) | 2.98520648 |
| 29 | Breech presentation (HP:0001623) | 2.97745641 |
| 30 | Mild short stature (HP:0003502) | 2.96342489 |
| 31 | Nonimmune hydrops fetalis (HP:0001790) | 2.93832656 |
| 32 | Cervical subluxation (HP:0003308) | 2.91835773 |
| 33 | Bell-shaped thorax (HP:0001591) | 2.90532340 |
| 34 | Dilatation of the ascending aorta (HP:0005111) | 2.89023695 |
| 35 | Biconcave vertebral bodies (HP:0004586) | 2.66817102 |
| 36 | Infantile muscular hypotonia (HP:0008947) | 2.62671605 |
| 37 | Delayed closure of the anterior fontanelle (HP:0001476) | 2.61604746 |
| 38 | Abnormality of the ischium (HP:0003174) | 2.60784721 |
| 39 | Abnormal delivery (HP:0001787) | 2.52687833 |
| 40 | Mesangial abnormality (HP:0001966) | 2.47963162 |
| 41 | Mitral valve prolapse (HP:0001634) | 2.47670603 |
| 42 | Delayed cranial suture closure (HP:0000270) | 2.47197515 |
| 43 | Hyperextensible skin (HP:0000974) | 2.46854281 |
| 44 | Aortic regurgitation (HP:0001659) | 2.43257456 |
| 45 | Mesomelia (HP:0003027) | 2.41116459 |
| 46 | Joint laxity (HP:0001388) | 2.39566316 |
| 47 | Increased corneal curvature (HP:0100692) | 2.34942135 |
| 48 | Keratoconus (HP:0000563) | 2.34942135 |
| 49 | Spinal rigidity (HP:0003306) | 2.34327086 |
| 50 | Cerebral aneurysm (HP:0004944) | 2.33079762 |
| 51 | Increased variability in muscle fiber diameter (HP:0003557) | 2.32917622 |
| 52 | Hypoplasia of the iris (HP:0007676) | 2.28097739 |
| 53 | Microglossia (HP:0000171) | 2.27946360 |
| 54 | Turricephaly (HP:0000262) | 2.27207454 |
| 55 | Delayed gross motor development (HP:0002194) | 2.27103440 |
| 56 | Morphological abnormality of the middle ear (HP:0008609) | 2.26596892 |
| 57 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 2.24711212 |
| 58 | Redundant skin (HP:0001582) | 2.24561473 |
| 59 | Partial duplication of the phalanx of hand (HP:0009999) | 2.24047704 |
| 60 | Osteolytic defects of the hand bones (HP:0009699) | 2.20661860 |
| 61 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.20661860 |
| 62 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.18137023 |
| 63 | Ovoid vertebral bodies (HP:0003300) | 2.15638185 |
| 64 | Tibial bowing (HP:0002982) | 2.08727051 |
| 65 | Aplasia of the musculature (HP:0100854) | 2.06196622 |
| 66 | Osteoarthritis (HP:0002758) | 2.05603489 |
| 67 | Gingival overgrowth (HP:0000212) | 2.02966033 |
| 68 | Abnormality of the acetabulum (HP:0003170) | 2.02702922 |
| 69 | Fibular hypoplasia (HP:0003038) | 2.02030558 |
| 70 | Aortic valve stenosis (HP:0001650) | 2.01078549 |
| 71 | Abnormality of the 2nd finger (HP:0004100) | 1.98954546 |
| 72 | Ulnar bowing (HP:0003031) | 1.98330281 |
| 73 | Coxa vara (HP:0002812) | 1.98193449 |
| 74 | Elbow flexion contracture (HP:0002987) | 1.97152558 |
| 75 | Abnormality of skull ossification (HP:0002703) | 1.97129888 |
| 76 | Overgrowth (HP:0001548) | 1.97094848 |
| 77 | Striae distensae (HP:0001065) | 1.95329811 |
| 78 | Long toe (HP:0010511) | 1.94970896 |
| 79 | Femoral bowing (HP:0002980) | 1.94874318 |
| 80 | Metaphyseal dysplasia (HP:0100255) | 1.93272130 |
| 81 | Deviation of the hallux (HP:0010051) | 1.92426886 |
| 82 | Protruding ear (HP:0000411) | 1.91220192 |
| 83 | Decreased skull ossification (HP:0004331) | 1.90694305 |
| 84 | Coronal craniosynostosis (HP:0004440) | 1.89612784 |
| 85 | Joint stiffness (HP:0001387) | 1.89325540 |
| 86 | Ectopia lentis (HP:0001083) | 1.89209102 |
| 87 | Venous insufficiency (HP:0005293) | 1.87628431 |
| 88 | Hallux valgus (HP:0001822) | 1.87372936 |
| 89 | Mitral regurgitation (HP:0001653) | 1.86092912 |
| 90 | Generalized amyotrophy (HP:0003700) | 1.85941236 |
| 91 | Sparse lateral eyebrow (HP:0005338) | 1.82737518 |
| 92 | Limited hip movement (HP:0008800) | 1.82109169 |
| 93 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.81361595 |
| 94 | Congenital, generalized hypertrichosis (HP:0004540) | 1.79919204 |
| 95 | Abnormality of the frontal sinuses (HP:0002687) | 1.79762838 |
| 96 | Narrow palate (HP:0000189) | 1.78566440 |
| 97 | Recurrent corneal erosions (HP:0000495) | 1.76529392 |
| 98 | Vertebral compression fractures (HP:0002953) | 1.76423559 |
| 99 | Hypoventilation (HP:0002791) | 1.73535870 |
| 100 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.72693242 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | INSRR | 4.91069710 |
| 2 | EPHB2 | 4.00241728 |
| 3 | DDR2 | 3.71079200 |
| 4 | MYLK | 3.65725690 |
| 5 | PDGFRA | 3.56980326 |
| 6 | TRIB3 | 3.06207478 |
| 7 | MARK1 | 2.82942323 |
| 8 | ABL2 | 2.37451673 |
| 9 | WNK3 | 2.28572917 |
| 10 | PAK2 | 2.27777613 |
| 11 | KIT | 2.11999643 |
| 12 | SIK1 | 2.11419446 |
| 13 | ADRBK2 | 2.04378428 |
| 14 | ADRBK1 | 1.84008406 |
| 15 | TGFBR2 | 1.74509858 |
| 16 | MARK2 | 1.69277539 |
| 17 | MAP4K2 | 1.66857938 |
| 18 | PDGFRB | 1.56518493 |
| 19 | MAPK13 | 1.51733576 |
| 20 | MAPK15 | 1.47351206 |
| 21 | RPS6KA4 | 1.44159625 |
| 22 | PAK3 | 1.43320843 |
| 23 | AKT3 | 1.34386793 |
| 24 | GSK3A | 1.33924663 |
| 25 | LIMK1 | 1.33727035 |
| 26 | NTRK3 | 1.28454608 |
| 27 | CDC42BPA | 1.27484468 |
| 28 | PTK2 | 1.26790518 |
| 29 | PRKD2 | 1.26568901 |
| 30 | BMPR1B | 1.20605995 |
| 31 | TAF1 | 1.18078518 |
| 32 | ILK | 1.17552745 |
| 33 | CASK | 1.08617504 |
| 34 | VRK2 | 1.08291408 |
| 35 | MAP3K2 | 1.07618898 |
| 36 | NLK | 1.05082635 |
| 37 | TRPM7 | 1.04149554 |
| 38 | NME1 | 1.01297567 |
| 39 | STK16 | 1.00053669 |
| 40 | MAPKAPK3 | 0.98994918 |
| 41 | ERN1 | 0.96980825 |
| 42 | PIK3CG | 0.95038824 |
| 43 | PHKG1 | 0.92843895 |
| 44 | PHKG2 | 0.92843895 |
| 45 | DYRK2 | 0.89432892 |
| 46 | PKN1 | 0.88685527 |
| 47 | NEK9 | 0.88401005 |
| 48 | NTRK1 | 0.87147518 |
| 49 | GRK1 | 0.86286636 |
| 50 | MAP2K1 | 0.85540699 |
| 51 | ROCK1 | 0.85196029 |
| 52 | FRK | 0.85178639 |
| 53 | CAMKK2 | 0.85136559 |
| 54 | TYK2 | 0.83627677 |
| 55 | EIF2AK2 | 0.80451463 |
| 56 | GRK5 | 0.79400222 |
| 57 | MAPKAPK5 | 0.79008933 |
| 58 | STK38 | 0.78373731 |
| 59 | CLK1 | 0.76119493 |
| 60 | STK38L | 0.75777076 |
| 61 | TGFBR1 | 0.74901731 |
| 62 | MET | 0.73625094 |
| 63 | TESK1 | 0.71899412 |
| 64 | PAK6 | 0.71880608 |
| 65 | CAMK1D | 0.67704122 |
| 66 | JAK1 | 0.67359846 |
| 67 | CAMK2G | 0.66739518 |
| 68 | MAPK7 | 0.65481543 |
| 69 | PIK3CA | 0.63162950 |
| 70 | ACVR1B | 0.60524335 |
| 71 | LATS2 | 0.60508575 |
| 72 | LATS1 | 0.58390497 |
| 73 | GRK7 | 0.57379968 |
| 74 | CAMK2D | 0.55280971 |
| 75 | STK3 | 0.54220268 |
| 76 | MAPK12 | 0.53083163 |
| 77 | CDK3 | 0.50995911 |
| 78 | CAMK2A | 0.50319668 |
| 79 | PRKCE | 0.50124923 |
| 80 | RIPK1 | 0.47614760 |
| 81 | CHEK2 | 0.41777808 |
| 82 | MAP3K7 | 0.41420439 |
| 83 | TTN | 0.39573512 |
| 84 | PRKG1 | 0.39267470 |
| 85 | INSR | 0.38630696 |
| 86 | HIPK2 | 0.37253458 |
| 87 | CAMK1 | 0.37032124 |
| 88 | PRKD1 | 0.36574135 |
| 89 | SIK2 | 0.35480874 |
| 90 | VRK1 | 0.35385532 |
| 91 | MAPK4 | 0.33797352 |
| 92 | TNIK | 0.33655963 |
| 93 | KSR2 | 0.33099851 |
| 94 | CAMK4 | 0.32675721 |
| 95 | PTK2B | 0.32163977 |
| 96 | MUSK | 0.28662439 |
| 97 | PAK4 | 0.28549021 |
| 98 | ABL1 | 0.28245948 |
| 99 | CAMK1G | 0.28034979 |
| 100 | STK39 | 0.25680980 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ECM-receptor interaction_Homo sapiens_hsa04512 | 5.32717285 |
| 2 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 4.42820692 |
| 3 | Protein digestion and absorption_Homo sapiens_hsa04974 | 3.56394541 |
| 4 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.92608670 |
| 5 | Focal adhesion_Homo sapiens_hsa04510 | 2.60544178 |
| 6 | Basal cell carcinoma_Homo sapiens_hsa05217 | 2.51951321 |
| 7 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.37499462 |
| 8 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.30641225 |
| 9 | Amoebiasis_Homo sapiens_hsa05146 | 2.01477145 |
| 10 | Melanoma_Homo sapiens_hsa05218 | 2.01296871 |
| 11 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.93786216 |
| 12 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.90149887 |
| 13 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.78725949 |
| 14 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.75781349 |
| 15 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.69656201 |
| 16 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.68512758 |
| 17 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.63659998 |
| 18 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.62607998 |
| 19 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.61935713 |
| 20 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.59716428 |
| 21 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.53585060 |
| 22 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.50576259 |
| 23 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.42595036 |
| 24 | Malaria_Homo sapiens_hsa05144 | 1.34186719 |
| 25 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.31044196 |
| 26 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.28758043 |
| 27 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.28339619 |
| 28 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.22247110 |
| 29 | Cocaine addiction_Homo sapiens_hsa05030 | 1.22187648 |
| 30 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.22047183 |
| 31 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.20078664 |
| 32 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.17600856 |
| 33 | Nicotine addiction_Homo sapiens_hsa05033 | 1.17012316 |
| 34 | Pathways in cancer_Homo sapiens_hsa05200 | 1.08581309 |
| 35 | Wnt signaling pathway_Homo sapiens_hsa04310 | 1.06165676 |
| 36 | Bladder cancer_Homo sapiens_hsa05219 | 1.02805851 |
| 37 | Axon guidance_Homo sapiens_hsa04360 | 1.00361850 |
| 38 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.98721183 |
| 39 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.98563057 |
| 40 | Melanogenesis_Homo sapiens_hsa04916 | 0.96642755 |
| 41 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.94000344 |
| 42 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.92702265 |
| 43 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.87331603 |
| 44 | Prostate cancer_Homo sapiens_hsa05215 | 0.85540815 |
| 45 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.82708784 |
| 46 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.80430357 |
| 47 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.79255548 |
| 48 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.76140808 |
| 49 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.74965476 |
| 50 | Platelet activation_Homo sapiens_hsa04611 | 0.74883470 |
| 51 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.73840515 |
| 52 | Gap junction_Homo sapiens_hsa04540 | 0.72499819 |
| 53 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.71583029 |
| 54 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.71112623 |
| 55 | Adherens junction_Homo sapiens_hsa04520 | 0.71012037 |
| 56 | Pertussis_Homo sapiens_hsa05133 | 0.70554899 |
| 57 | Sulfur relay system_Homo sapiens_hsa04122 | 0.65548960 |
| 58 | Long-term depression_Homo sapiens_hsa04730 | 0.58869244 |
| 59 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.58759249 |
| 60 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.56171348 |
| 61 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.55964459 |
| 62 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.55816026 |
| 63 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.54778346 |
| 64 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.52058710 |
| 65 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.51830669 |
| 66 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.51522017 |
| 67 | Mineral absorption_Homo sapiens_hsa04978 | 0.50199049 |
| 68 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.48901270 |
| 69 | Renin secretion_Homo sapiens_hsa04924 | 0.48715013 |
| 70 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.48680429 |
| 71 | Colorectal cancer_Homo sapiens_hsa05210 | 0.47854781 |
| 72 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.47229384 |
| 73 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.44278701 |
| 74 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.43926658 |
| 75 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.42625562 |
| 76 | Glioma_Homo sapiens_hsa05214 | 0.42449600 |
| 77 | Morphine addiction_Homo sapiens_hsa05032 | 0.42358445 |
| 78 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.42144735 |
| 79 | Prion diseases_Homo sapiens_hsa05020 | 0.40712471 |
| 80 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.39309418 |
| 81 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.38336225 |
| 82 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.38102400 |
| 83 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.37941796 |
| 84 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.37582009 |
| 85 | GABAergic synapse_Homo sapiens_hsa04727 | 0.37418635 |
| 86 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.36829419 |
| 87 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.36520115 |
| 88 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.36028185 |
| 89 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.35843477 |
| 90 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.35610903 |
| 91 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.34564473 |
| 92 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.33653513 |
| 93 | Alzheimers disease_Homo sapiens_hsa05010 | 0.30995155 |
| 94 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.27533810 |
| 95 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.26894355 |
| 96 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.26674840 |
| 97 | HTLV-I infection_Homo sapiens_hsa05166 | 0.26003869 |
| 98 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.25846776 |
| 99 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.25329978 |
| 100 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.24727673 |

