MYF5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of fatty acid transport (GO:2000193)9.21448662
2membrane raft organization (GO:0031579)8.28844809
3folic acid transport (GO:0015884)7.37738839
4striated muscle atrophy (GO:0014891)7.12693121
5skeletal muscle contraction (GO:0003009)7.09736405
6negative regulation of nitric-oxide synthase activity (GO:0051001)7.01620920
7response to gravity (GO:0009629)6.83283656
8response to muscle activity (GO:0014850)6.74931405
9muscle atrophy (GO:0014889)6.44766463
10regulation of fatty acid transport (GO:2000191)6.36587744
11negative regulation of peptidyl-threonine phosphorylation (GO:0010801)6.25099412
12lymphangiogenesis (GO:0001946)6.22488868
13organ induction (GO:0001759)6.08544319
14regulation of extracellular matrix disassembly (GO:0010715)6.07454810
15negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)5.97356716
16lung epithelium development (GO:0060428)5.80564549
17membrane assembly (GO:0071709)5.78551477
18negative regulation of Ras GTPase activity (GO:0034261)5.73037755
19neuromuscular synaptic transmission (GO:0007274)5.71654300
20* skeletal muscle tissue development (GO:0007519)5.47324182
21branch elongation of an epithelium (GO:0060602)5.44347520
22regulation of bile acid biosynthetic process (GO:0070857)5.43214684
23postsynaptic membrane organization (GO:0001941)5.41274364
24skeletal muscle tissue regeneration (GO:0043403)5.40539059
25actin-myosin filament sliding (GO:0033275)5.31784010
26muscle filament sliding (GO:0030049)5.31784010
27regulation of integrin-mediated signaling pathway (GO:2001044)5.09856970
28positive regulation of organic acid transport (GO:0032892)5.07816403
29positive regulation of immune response to tumor cell (GO:0002839)4.91964445
30regulation of immune response to tumor cell (GO:0002837)4.91964445
31regulation of response to tumor cell (GO:0002834)4.91964445
32positive regulation of response to tumor cell (GO:0002836)4.91964445
33heart process (GO:0003015)4.90261145
34heart contraction (GO:0060047)4.90261145
35negative regulation of skeletal muscle tissue development (GO:0048642)4.86431499
36regulation of metalloenzyme activity (GO:0048552)4.85171998
37* muscle cell fate commitment (GO:0042693)4.80543375
38actin-mediated cell contraction (GO:0070252)4.80247041
39retina vasculature morphogenesis in camera-type eye (GO:0061299)4.79144804
40positive regulation of vesicle fusion (GO:0031340)4.79015697
41regulation of cholesterol homeostasis (GO:2000188)4.77882816
42regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.69913355
43activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)4.68204774
44positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr4.65325871
45axis elongation (GO:0003401)4.62161005
46regulation of vascular endothelial growth factor signaling pathway (GO:1900746)4.52631386
47response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.38498226
48maintenance of protein localization in endoplasmic reticulum (GO:0035437)4.32124437
49synaptic transmission, cholinergic (GO:0007271)4.31681665
50regulation of extracellular matrix organization (GO:1903053)4.26071514
51negative regulation of monooxygenase activity (GO:0032769)4.20910815
52developmental induction (GO:0031128)4.16480746
53myotube cell development (GO:0014904)4.14032936
54neuronal action potential (GO:0019228)4.11746223
55establishment of mitotic spindle orientation (GO:0000132)4.10851402
56regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 4.08124789
57actin filament depolymerization (GO:0030042)4.02332136
58skeletal muscle adaptation (GO:0043501)4.01760739
59peristalsis (GO:0030432)4.01045738
60cell-cell signaling involved in cell fate commitment (GO:0045168)3.99683653
61tongue development (GO:0043586)3.96008425
62regulation of branching involved in salivary gland morphogenesis (GO:0060693)3.95817780
63neuromuscular junction development (GO:0007528)3.93135618
64sarcomere organization (GO:0045214)3.90636121
65negative regulation of JAK-STAT cascade (GO:0046426)3.89256838
66nuclear pore complex assembly (GO:0051292)3.88006847
67generation of neurons (GO:0048699)3.87447690
68positive regulation of cell junction assembly (GO:1901890)3.81417889
69positive regulation of focal adhesion assembly (GO:0051894)3.81417889
70myotube differentiation (GO:0014902)3.80119184
71regulation of skeletal muscle contraction (GO:0014819)3.79471817
72outer ear morphogenesis (GO:0042473)3.79092943
73positive regulation of myoblast differentiation (GO:0045663)3.78211424
74mesenchymal-epithelial cell signaling (GO:0060638)3.75946952
75positive regulation of blood coagulation (GO:0030194)3.75389084
76positive regulation of hemostasis (GO:1900048)3.75389084
77* striated muscle tissue development (GO:0014706)3.75359458
78positive regulation of extracellular matrix organization (GO:1903055)3.73576575
79fibroblast migration (GO:0010761)3.73485386
80positive regulation of adherens junction organization (GO:1903393)3.70574203
81negative regulation of muscle hypertrophy (GO:0014741)3.68782342
82striated muscle contraction (GO:0006941)3.68459174
83protein heterotetramerization (GO:0051290)3.67209544
84positive regulation of astrocyte differentiation (GO:0048711)3.67175035
85endocardial cushion morphogenesis (GO:0003203)3.65313559
86Notch signaling involved in heart development (GO:0061314)3.62070156
87regulation of organ formation (GO:0003156)3.56743832
88* muscle organ development (GO:0007517)3.53004668
89cytoskeletal anchoring at plasma membrane (GO:0007016)3.52724730
90establishment of mitotic spindle localization (GO:0040001)3.51440785
91response to hyperoxia (GO:0055093)3.46846147
92response to increased oxygen levels (GO:0036296)3.46846147
93heart valve morphogenesis (GO:0003179)3.45890180
94* muscle structure development (GO:0061061)3.45408992
95actin filament-based movement (GO:0030048)3.44677542
96morphogenesis of an epithelial sheet (GO:0002011)3.44167696
97paraxial mesoderm development (GO:0048339)3.41546872
98positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190)3.39482663
99* muscle tissue development (GO:0060537)3.38348786
100positive regulation of metanephros development (GO:0072216)3.36040501
101vagina development (GO:0060068)3.35985707
102positive regulation of coagulation (GO:0050820)3.34801207
103positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.31958426
104striated muscle cell proliferation (GO:0014855)3.31752768
105positive regulation of fibroblast proliferation (GO:0048146)3.29868395
106venous blood vessel morphogenesis (GO:0048845)3.27878498
107metanephric mesenchyme development (GO:0072075)3.27344508
108regulation of organic acid transport (GO:0032890)3.25187089
109negative regulation of osteoclast differentiation (GO:0045671)3.24339457
110establishment of spindle orientation (GO:0051294)3.22698869
111negative regulation of nitric oxide biosynthetic process (GO:0045019)3.20935685
112membrane budding (GO:0006900)3.19924527
113sprouting angiogenesis (GO:0002040)3.19083405
114negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.18208425
115positive regulation of DNA biosynthetic process (GO:2000573)3.18118072
116dorsal/ventral neural tube patterning (GO:0021904)3.14076313
117negative regulation of anoikis (GO:2000811)3.11466407
118myoblast fusion (GO:0007520)3.11465824
119embryonic cranial skeleton morphogenesis (GO:0048701)3.10142376
120response to inactivity (GO:0014854)3.09641819
121eye photoreceptor cell differentiation (GO:0001754)3.08331343
122photoreceptor cell differentiation (GO:0046530)3.08331343
123organ growth (GO:0035265)3.07245235
124plasma membrane repair (GO:0001778)3.06817957
125cardiac myofibril assembly (GO:0055003)3.06712982
126positive regulation of lipid transport (GO:0032370)3.06543370
127negative regulation of peptidyl-serine phosphorylation (GO:0033137)3.06496521
128definitive hemopoiesis (GO:0060216)3.06477214
129muscle fiber development (GO:0048747)3.06240792
130regulation of synapse assembly (GO:0051963)3.05894647
131myoblast migration (GO:0051451)3.04810053
132positive regulation of myotube differentiation (GO:0010831)3.02942549
133skeletal muscle fiber development (GO:0048741)3.02087880
134branching involved in salivary gland morphogenesis (GO:0060445)2.98872596
135cellular response to zinc ion (GO:0071294)2.98115598
136positive regulation of wound healing (GO:0090303)2.96561493
137nuclear pore organization (GO:0006999)2.95310351
138cellular response to dexamethasone stimulus (GO:0071549)2.94934261
139regulation of secondary heart field cardioblast proliferation (GO:0003266)2.94398159
140regulation of cardioblast proliferation (GO:0003264)2.94398159
141mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.93486677
142positive regulation of mesenchymal cell proliferation (GO:0002053)2.93212197
143ureteric bud development (GO:0001657)2.93084340
144cell migration involved in heart development (GO:0060973)2.93051526
145spinal cord association neuron differentiation (GO:0021527)2.92342921
146collagen fibril organization (GO:0030199)2.92289877
147* muscle tissue morphogenesis (GO:0060415)2.91913964
148Rac protein signal transduction (GO:0016601)2.91885477
149kidney mesenchyme development (GO:0072074)2.91204684
150cellular response to interferon-alpha (GO:0035457)2.89165149
151negative regulation of endothelial cell proliferation (GO:0001937)2.88703978
152regulation of glucose import in response to insulin stimulus (GO:2001273)2.87087183
153multicellular organismal movement (GO:0050879)2.86910212
154musculoskeletal movement (GO:0050881)2.86910212
155negative regulation of BMP signaling pathway (GO:0030514)2.86298394
156nephron tubule formation (GO:0072079)2.83969239
157actomyosin structure organization (GO:0031032)2.82916289
158fibrinolysis (GO:0042730)2.82243640
159positive regulation of mesonephros development (GO:0061213)2.81024318
160anterior/posterior axis specification, embryo (GO:0008595)2.80109317
161regulation of fibroblast growth factor receptor signaling pathway (GO:0040036)2.79970186
162regulation of relaxation of muscle (GO:1901077)2.77609321
163mesonephric tubule development (GO:0072164)2.77486203
164myofibril assembly (GO:0030239)2.77154353
165positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.76708528
166mitotic nuclear envelope reassembly (GO:0007084)2.76454980
167nuclear envelope reassembly (GO:0031468)2.76454980
168positive regulation of steroid hormone secretion (GO:2000833)2.76129096
169positive regulation of macrophage activation (GO:0043032)2.74824203
170skin morphogenesis (GO:0043589)2.74792130
171cellular response to glucocorticoid stimulus (GO:0071385)2.74330621
172positive regulation of natural killer cell differentiation (GO:0032825)2.74206815
173peripheral nervous system axon ensheathment (GO:0032292)2.73948236
174myelination in peripheral nervous system (GO:0022011)2.73948236
175striated muscle cell development (GO:0055002)2.73631581
176negative regulation of fatty acid transport (GO:2000192)2.73169551
177regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.72886955
178pore complex assembly (GO:0046931)2.72808439
179middle ear morphogenesis (GO:0042474)2.70323449
180epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.69957404
181mesonephric epithelium development (GO:0072163)2.69794727
182muscle cell cellular homeostasis (GO:0046716)11.9734863

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.82583202
2SALL1_21062744_ChIP-ChIP_HESCs_Human4.49925125
3TRIM28_21343339_ChIP-Seq_HEK293_Human3.85808749
4ZNF652_21678463_ChIP-ChIP_ZR75-1_Human3.68958303
5AR_21572438_ChIP-Seq_LNCaP_Human3.66618867
6RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.47459163
7PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.32857974
8EGR1_19374776_ChIP-ChIP_THP-1_Human3.15002241
9NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.06956029
10CLOCK_20551151_ChIP-Seq_293T_Human2.79904878
11SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.78077224
12TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.77327675
13MEF2A_21415370_ChIP-Seq_HL-1_Mouse2.59506942
14RBPJ_22232070_ChIP-Seq_NCS_Mouse2.56139934
15HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.53224511
16ZNF274_21170338_ChIP-Seq_K562_Hela2.42042433
17STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.37179767
18TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.27937644
19PIAS1_25552417_ChIP-Seq_VCAP_Human2.25835822
20WT1_19549856_ChIP-ChIP_CCG9911_Human2.16594751
21TP63_17297297_ChIP-ChIP_HaCaT_Human2.11327873
22ZFP57_27257070_Chip-Seq_ESCs_Mouse2.11296926
23ZNF217_24962896_ChIP-Seq_MCF-7_Human2.09079172
24CJUN_26792858_Chip-Seq_BT549_Human2.08048312
25PCGF2_27294783_Chip-Seq_NPCs_Mouse2.06242187
26ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.06189714
27ESR2_21235772_ChIP-Seq_MCF-7_Human2.05068329
28PPAR_26484153_Chip-Seq_NCI-H1993_Human2.03275225
29E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.01969474
30EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.00418293
31CDX2_20551321_ChIP-Seq_CACO-2_Human2.00152230
32CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.98379374
33BRD4_25478319_ChIP-Seq_HGPS_Human1.94944632
34WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.94838195
35RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.94477410
36ELK1_22589737_ChIP-Seq_MCF10A_Human1.93542720
37BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.90824011
38EP300_21415370_ChIP-Seq_HL-1_Mouse1.86389839
39SALL4_18804426_ChIP-ChIP_XEN_Mouse1.84895840
40ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.82864743
41NR3C1_21868756_ChIP-Seq_MCF10A_Human1.81074251
42RXR_22108803_ChIP-Seq_LS180_Human1.80353647
43RARG_19884340_ChIP-ChIP_MEFs_Mouse1.79635833
44GATA1_22025678_ChIP-Seq_K562_Human1.79526133
45NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.79491801
46SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.79302593
47SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.79302593
48BCAT_22108803_ChIP-Seq_LS180_Human1.77094675
49ESR1_21235772_ChIP-Seq_MCF-7_Human1.76665077
50FLI1_27457419_Chip-Seq_LIVER_Mouse1.73757102
51ELK1_19687146_ChIP-ChIP_HELA_Human1.73378687
52HIF1A_21447827_ChIP-Seq_MCF-7_Human1.71077461
53ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.70420761
54TP53_18474530_ChIP-ChIP_U2OS_Human1.68440178
55CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.67216133
56FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.66980376
57ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.66749013
58EZH2_27294783_Chip-Seq_NPCs_Mouse1.65985186
59PCGF2_27294783_Chip-Seq_ESCs_Mouse1.65307444
60SUZ12_27294783_Chip-Seq_NPCs_Mouse1.63926189
61* CRX_20693478_ChIP-Seq_RETINA_Mouse1.62386122
62NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.61964141
63DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.61654628
64GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.60432094
65SMAD_19615063_ChIP-ChIP_OVARY_Human1.60015933
66E2F7_22180533_ChIP-Seq_HELA_Human1.55759070
67TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.55277638
68TP53_16413492_ChIP-PET_HCT116_Human1.54083536
69TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.52891674
70TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.52480287
71GABP_17652178_ChIP-ChIP_JURKAT_Human1.52337791
72STAT6_21828071_ChIP-Seq_BEAS2B_Human1.49722071
73NFE2_27457419_Chip-Seq_LIVER_Mouse1.47439413
74* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.46657772
75SOX2_20726797_ChIP-Seq_SW620_Human1.45932301
76CTNNB1_20460455_ChIP-Seq_HCT116_Human1.44203346
77NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.44093158
78NRF2_20460467_ChIP-Seq_MEFs_Mouse1.44093158
79PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.43576233
80ESR1_20079471_ChIP-ChIP_T-47D_Human1.39550957
81CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.39020309
82CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.37475859
83P300_27058665_Chip-Seq_ZR-75-30cells_Human1.36979376
84STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.33689374
85TCF3_18692474_ChIP-Seq_MEFs_Mouse1.31306832
86TBX20_22328084_ChIP-Seq_HEART_Mouse1.28756546
87TBX20_22080862_ChIP-Seq_HEART_Mouse1.28756546
88ELK3_25401928_ChIP-Seq_HUVEC_Human1.28381217
89ZNF263_19887448_ChIP-Seq_K562_Human1.27676867
90TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.24632711
91MYB_21317192_ChIP-Seq_ERMYB_Mouse1.24232056
92* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.22724990
93RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.22131628
94SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.22023209
95VDR_24787735_ChIP-Seq_THP-1_Human1.21072630
96UBF1/2_26484160_Chip-Seq_HMECs_Human1.19987194
97AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.19426031
98TCF4_18268006_ChIP-ChIP_LS174T_Human1.18263889
99ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.17452975
100JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.16624426
101MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.16213225
102SRF_21415370_ChIP-Seq_HL-1_Mouse1.15430488
103STAT3_18555785_Chip-Seq_ESCs_Mouse1.15336925
104OCT4_21477851_ChIP-Seq_ESCs_Mouse1.15118913
105HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.15101638
106TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.14329329
107P53_22387025_ChIP-Seq_ESCs_Mouse1.14020184
108GATA2_21666600_ChIP-Seq_HMVEC_Human1.13769416
109KDM2B_26808549_Chip-Seq_REH_Human1.13279758
110* CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.13156305
111DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.12046958
112SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.11128228
113EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.10605119
114RUNX1_27457419_Chip-Seq_LIVER_Mouse1.09543372
115SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09053309
116FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.07509362
117OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07045003
118NANOG_18555785_Chip-Seq_ESCs_Mouse1.06819085
119TCF7_22412390_ChIP-Seq_EML_Mouse1.06316490
120SOX2_18555785_Chip-Seq_ESCs_Mouse1.05789303
121RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.05203563
122MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.04082882
123GATA4_21415370_ChIP-Seq_HL-1_Mouse1.01402914
124KDM2B_26808549_Chip-Seq_SUP-B15_Human1.00713781
125JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.00430680
126SCL_19346495_ChIP-Seq_HPC-7_Human1.00200339
127AR_21909140_ChIP-Seq_LNCAP_Human0.98324459
128ZFX_18555785_Chip-Seq_ESCs_Mouse0.98229202
129ATF3_27146783_Chip-Seq_COLON_Human0.97271196
130Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.97209760
131STAT3_1855785_ChIP-Seq_MESCs_Mouse0.97059964
132KDM2B_26808549_Chip-Seq_DND41_Human0.96505498
133LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96216564
134KDM2B_26808549_Chip-Seq_JURKAT_Human0.95867057
135ELK4_26923725_Chip-Seq_MESODERM_Mouse0.95757946
136PU1_27457419_Chip-Seq_LIVER_Mouse0.95369082
137ZFP281_18757296_ChIP-ChIP_E14_Mouse0.95200910
138EED_16625203_ChIP-ChIP_MESCs_Mouse0.94457518
139FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.93848896
140SALL4_22934838_ChIP-ChIP_CD34+_Human0.93671343
141STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.93281849
142FOXO3_23340844_ChIP-Seq_DLD1_Human0.92779250
143* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.92381748
144SMAD1_18555785_Chip-Seq_ESCs_Mouse0.92194356
145WT1_25993318_ChIP-Seq_PODOCYTE_Human0.91514672
146SMC1_22415368_ChIP-Seq_MEFs_Mouse0.91305839
147RAD21_21589869_ChIP-Seq_MESCs_Mouse0.90843393
148CDX2_22108803_ChIP-Seq_LS180_Human0.90548949
149SMC3_22415368_ChIP-Seq_MEFs_Mouse0.90044741
150KDM2B_26808549_Chip-Seq_K562_Human0.89571072
151NR3C1_23031785_ChIP-Seq_PC12_Mouse0.88750866
152CBP_20019798_ChIP-Seq_JUKART_Human0.88645331
153RNF2_18974828_ChIP-Seq_MESCs_Mouse0.88504402
154EZH2_18974828_ChIP-Seq_MESCs_Mouse0.88504402
155CDX2_19796622_ChIP-Seq_MESCs_Mouse0.87614812
156LXR_22158963_ChIP-Seq_LIVER_Mouse0.87276705

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004145_abnormal_muscle_electrophysio7.39162979
2MP0004270_analgesia5.49240835
3MP0003950_abnormal_plasma_membrane5.36752796
4MP0002163_abnormal_gland_morphology4.93647834
5MP0010368_abnormal_lymphatic_system4.74528852
6MP0005360_urolithiasis3.98944383
7MP0000747_muscle_weakness3.63909154
8MP0003191_abnormal_cellular_cholesterol3.23648443
9* MP0000750_abnormal_muscle_regeneration3.20765677
10MP0005379_endocrine/exocrine_gland_phen2.79833807
11MP0010030_abnormal_orbit_morphology2.76917610
12MP0004084_abnormal_cardiac_muscle2.73406534
13MP0006054_spinal_hemorrhage2.48686595
14MP0001177_atelectasis2.44777729
15MP0001299_abnormal_eye_distance/2.43174965
16MP0002877_abnormal_melanocyte_morpholog2.35711010
17* MP0000733_abnormal_muscle_development2.23808386
18MP0001879_abnormal_lymphatic_vessel2.22594198
19MP0003705_abnormal_hypodermis_morpholog2.18901217
20MP0003566_abnormal_cell_adhesion2.16651273
21MP0000749_muscle_degeneration2.13046499
22MP0008438_abnormal_cutaneous_collagen2.04329991
23MP0000013_abnormal_adipose_tissue2.02618627
24MP0003091_abnormal_cell_migration2.01565478
25MP0004233_abnormal_muscle_weight1.95820690
26MP0000751_myopathy1.90812929
27MP0000372_irregular_coat_pigmentation1.81081714
28* MP0000759_abnormal_skeletal_muscle1.72731602
29MP0001853_heart_inflammation1.70339434
30MP0003828_pulmonary_edema1.69594718
31MP0004036_abnormal_muscle_relaxation1.69164865
32* MP0002106_abnormal_muscle_physiology1.63427790
33MP0008961_abnormal_basal_metabolism1.63355227
34MP0002332_abnormal_exercise_endurance1.60456071
35MP0000767_abnormal_smooth_muscle1.58344848
36MP0002734_abnormal_mechanical_nocicepti1.50579156
37MP0000534_abnormal_ureter_morphology1.49083560
38MP0005388_respiratory_system_phenotype1.47795569
39MP0002133_abnormal_respiratory_system1.47795569
40MP0005623_abnormal_meninges_morphology1.44954646
41* MP0005369_muscle_phenotype1.39411370
42MP0003279_aneurysm1.38194195
43MP0005595_abnormal_vascular_smooth1.36808535
44MP0000428_abnormal_craniofacial_morphol1.35052244
45MP0005620_abnormal_muscle_contractility1.31149946
46MP0010352_gastrointestinal_tract_polyps1.29994374
47MP0003942_abnormal_urinary_system1.29702622
48MP0005023_abnormal_wound_healing1.29327317
49MP0000467_abnormal_esophagus_morphology1.26693414
50MP0002837_dystrophic_cardiac_calcinosis1.25053836
51MP0002168_other_aberrant_phenotype1.24915935
52MP0002751_abnormal_autonomic_nervous1.22497366
53MP0002972_abnormal_cardiac_muscle1.22195096
54MP0009250_abnormal_appendicular_skeleto1.18422222
55MP0002166_altered_tumor_susceptibility1.17024848
56MP0005330_cardiomyopathy1.14940934
57MP0009379_abnormal_foot_pigmentation1.13937004
58* MP0002108_abnormal_muscle_morphology1.13443814
59* MP0004087_abnormal_muscle_fiber1.12793258
60MP0002896_abnormal_bone_mineralization1.12096493
61MP0001958_emphysema1.11653614
62MP0004885_abnormal_endolymph1.07400281
63MP0000762_abnormal_tongue_morphology1.07390148
64MP0003300_gastrointestinal_ulcer1.05904740
65MP0002396_abnormal_hematopoietic_system1.03777929
66MP0005275_abnormal_skin_tensile1.02445800
67MP0001542_abnormal_bone_strength1.01857428
68MP0001849_ear_inflammation1.00775810
69MP0000003_abnormal_adipose_tissue0.96344715
70MP0000432_abnormal_head_morphology0.95857861
71MP0003115_abnormal_respiratory_system0.95475435
72MP0002060_abnormal_skin_morphology0.95473000
73MP0004215_abnormal_myocardial_fiber0.95278359
74MP0000858_altered_metastatic_potential0.95136511
75MP0005164_abnormal_response_to0.92055495
76MP0004858_abnormal_nervous_system0.90714529
77MP0003252_abnormal_bile_duct0.89650173
78MP0009053_abnormal_anal_canal0.85168766
79MP0003755_abnormal_palate_morphology0.84912925
80MP0001346_abnormal_lacrimal_gland0.83663647
81MP0002006_tumorigenesis0.83373727
82MP0002269_muscular_atrophy0.83346649
83MP0003935_abnormal_craniofacial_develop0.83201540
84MP0000049_abnormal_middle_ear0.83101995
85MP0005076_abnormal_cell_differentiation0.82997939
86MP0004197_abnormal_fetal_growth/weight/0.81948268
87MP0004883_abnormal_blood_vessel0.79854162
88MP0001663_abnormal_digestive_system0.78481889
89MP0001485_abnormal_pinna_reflex0.78221259
90MP0003943_abnormal_hepatobiliary_system0.77940438
91MP0008775_abnormal_heart_ventricle0.75678691
92MP0005508_abnormal_skeleton_morphology0.75612131
93MP0001661_extended_life_span0.74433593
94MP0000163_abnormal_cartilage_morphology0.74366557
95MP0003567_abnormal_fetal_cardiomyocyte0.74024185
96MP0003045_fibrosis0.72819772
97MP0005165_increased_susceptibility_to0.72657165
98MP0002282_abnormal_trachea_morphology0.72221631
99MP0001915_intracranial_hemorrhage0.72111514
100MP0002089_abnormal_postnatal_growth/wei0.70204776
101MP0004272_abnormal_basement_membrane0.67868415
102MP0005171_absent_coat_pigmentation0.66516656
103MP0000538_abnormal_urinary_bladder0.66356276
104MP0000955_abnormal_spinal_cord0.63500163
105MP0010630_abnormal_cardiac_muscle0.62776495
106MP0002177_abnormal_outer_ear0.62357143
107MP0003075_altered_response_to0.62215814
108MP0003195_calcinosis0.60607817
109* MP0002114_abnormal_axial_skeleton0.58642592
110MP0003122_maternal_imprinting0.58527660
111* MP0001943_abnormal_respiration0.58400023
112MP0003448_altered_tumor_morphology0.57100069
113MP0009780_abnormal_chondrocyte_physiolo0.57088261
114MP0004510_myositis0.56930304
115* MP0003959_abnormal_lean_body0.56864301
116MP0001175_abnormal_lung_morphology0.56784622
117MP0002233_abnormal_nose_morphology0.56781941
118MP0000569_abnormal_digit_pigmentation0.56224644
119MP0002009_preneoplasia0.55768318
120MP0002184_abnormal_innervation0.55618407
121MP0002925_abnormal_cardiovascular_devel0.55270900
122MP0005503_abnormal_tendon_morphology0.54429018
123* MP0002113_abnormal_skeleton_development0.53819886
124* MP0002081_perinatal_lethality0.53216166
125MP0002128_abnormal_blood_circulation0.52327281
126MP0003948_abnormal_gas_homeostasis0.51725205
127MP0005197_abnormal_uvea_morphology0.51394840
128MP0002295_abnormal_pulmonary_circulatio0.50508885
129MP0005395_other_phenotype0.50054265
130MP0004808_abnormal_hematopoietic_stem0.48852592
131* MP0002932_abnormal_joint_morphology0.48113915
132MP0004134_abnormal_chest_morphology0.47151922
133MP0002116_abnormal_craniofacial_bone0.47042649
134MP0009384_cardiac_valve_regurgitation0.46854234
135MP0001243_abnormal_dermal_layer0.46472403
136MP0003137_abnormal_impulse_conducting0.46404898
137MP0005385_cardiovascular_system_phenoty0.45973398
138MP0001544_abnormal_cardiovascular_syste0.45973398
139MP0000681_abnormal_thyroid_gland0.45389653
140MP0006138_congestive_heart_failure0.44728718
141MP0003011_delayed_dark_adaptation0.43719376
142MP0002160_abnormal_reproductive_system0.43676425
143MP0001881_abnormal_mammary_gland0.42682453
144MP0002090_abnormal_vision0.42658342

Predicted human phenotypes

RankGene SetZ-score
1Type 2 muscle fiber atrophy (HP:0003554)9.98395935
2Muscle fiber atrophy (HP:0100295)9.11600553
3Fatigable weakness (HP:0003473)7.55667116
4Abnormality of the neuromuscular junction (HP:0003398)7.55667116
5Aplasia of the musculature (HP:0100854)7.35089450
6Nonprogressive disorder (HP:0003680)6.91496027
7Weak cry (HP:0001612)6.67510056
8Easy fatigability (HP:0003388)5.90144801
9Akinesia (HP:0002304)5.60314526
10Decreased muscle mass (HP:0003199)4.90097534
11Aplasia/Hypoplasia involving the musculature (HP:0001460)4.57130458
12Distal lower limb amyotrophy (HP:0008944)4.57021523
13Gowers sign (HP:0003391)4.54594832
14Spinal rigidity (HP:0003306)4.53618217
15Cystic hygroma (HP:0000476)4.37468047
16Spinal cord lesions (HP:0100561)4.27212144
17Syringomyelia (HP:0003396)4.27212144
18Difficulty climbing stairs (HP:0003551)4.02791729
19Abnormalities of placenta or umbilical cord (HP:0001194)4.01300245
20Premature rupture of membranes (HP:0001788)3.95486087
21Lower limb amyotrophy (HP:0007210)3.69825761
22Short nail (HP:0001799)3.60001814
23Increased connective tissue (HP:0009025)3.57586693
24Pelvic girdle muscle weakness (HP:0003749)3.55906760
25Hypoplastic heart (HP:0001961)3.49917323
26Shoulder girdle muscle weakness (HP:0003547)3.47530898
27Ileus (HP:0002595)3.44692619
28Bulbar palsy (HP:0001283)3.43494656
29Abnormality of the calf musculature (HP:0001430)3.38280269
30Abnormality of the musculature of the pelvis (HP:0001469)3.28674323
31Abnormality of the hip-girdle musculature (HP:0001445)3.28674323
32Difficulty running (HP:0009046)3.09615294
33EMG: myopathic abnormalities (HP:0003458)3.00367559
34Poor suck (HP:0002033)2.97568111
35Broad metatarsal (HP:0001783)2.96834485
36Popliteal pterygium (HP:0009756)2.93814117
37Diminished movement (HP:0002374)2.89696446
38Osteolytic defects of the hand bones (HP:0009699)2.87309723
39Osteolytic defects of the phalanges of the hand (HP:0009771)2.87309723
40Bronchomalacia (HP:0002780)2.86430783
41Respiratory insufficiency due to muscle weakness (HP:0002747)2.84117382
42Calf muscle hypertrophy (HP:0008981)2.79416416
43Increased density of long bones (HP:0006392)2.79364815
44Mildly elevated creatine phosphokinase (HP:0008180)2.78072459
45Submucous cleft hard palate (HP:0000176)2.76474415
46Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.75865321
47Limb-girdle muscle atrophy (HP:0003797)2.65083850
48Muscular dystrophy (HP:0003560)2.64211299
49Shallow orbits (HP:0000586)2.63464843
50Myotonia (HP:0002486)2.61381227
51Long clavicles (HP:0000890)2.58609445
52Malignant hyperthermia (HP:0002047)2.58163190
53Limb-girdle muscle weakness (HP:0003325)2.56639691
54Depressed nasal tip (HP:0000437)2.54113330
55Muscle hypertrophy of the lower extremities (HP:0008968)2.51274386
56Muscle fiber inclusion bodies (HP:0100299)2.50029794
57Abnormality of the umbilical cord (HP:0010881)2.49621672
58Thin ribs (HP:0000883)2.49076200
59Protrusio acetabuli (HP:0003179)2.47725487
60Generalized amyotrophy (HP:0003700)2.36929095
61Amniotic constriction ring (HP:0009775)2.36514814
62Abnormality of placental membranes (HP:0011409)2.36514814
63Distal lower limb muscle weakness (HP:0009053)2.35334229
64Abnormality of the distal phalanges of the toes (HP:0010182)2.30274182
65Ankle contracture (HP:0006466)2.29105332
66Diaphragmatic weakness (HP:0009113)2.27422461
67Absent frontal sinuses (HP:0002688)2.26000920
68Rhabdomyosarcoma (HP:0002859)2.24000599
69Mitral stenosis (HP:0001718)2.23139083
70Webbed neck (HP:0000465)2.22587744
71Round ear (HP:0100830)2.18984120
72Distal arthrogryposis (HP:0005684)2.17130575
73Bradycardia (HP:0001662)2.16383857
74Absent phalangeal crease (HP:0006109)2.16151430
75Hyporeflexia of lower limbs (HP:0002600)2.15002602
76Muscle fiber splitting (HP:0003555)2.13284504
77Enlarged penis (HP:0000040)2.08511139
78Short thorax (HP:0010306)2.08446862
79Abnormality of the nasal septum (HP:0000419)2.07478630
80Turricephaly (HP:0000262)2.06757077
81Upper limb muscle weakness (HP:0003484)2.03074615
82Aortic dissection (HP:0002647)2.00204428
83Axonal loss (HP:0003447)1.97276189
84Generalized muscle weakness (HP:0003324)1.92660880
85Arthrogryposis multiplex congenita (HP:0002804)1.91507566
86Achilles tendon contracture (HP:0001771)1.91341764
87Stillbirth (HP:0003826)1.90838223
88Myocardial infarction (HP:0001658)1.88758845
89Arterial tortuosity (HP:0005116)1.88590712
90Toxemia of pregnancy (HP:0100603)1.87229612
91Absent septum pellucidum (HP:0001331)1.86513050
92Advanced eruption of teeth (HP:0006288)1.86033631
93Slender long bone (HP:0003100)1.85848152
94Reduced subcutaneous adipose tissue (HP:0003758)1.83820276
95Abnormality of the Achilles tendon (HP:0005109)1.82718050
96Aplasia involving bones of the upper limbs (HP:0009823)1.82311610
97Aplasia of the phalanges of the hand (HP:0009802)1.82311610
98Aplasia involving bones of the extremities (HP:0009825)1.82311610
99Wormian bones (HP:0002645)1.82156165
100Fetal akinesia sequence (HP:0001989)1.79399599
101Thin bony cortex (HP:0002753)1.76082354
102Biconcave vertebral bodies (HP:0004586)1.75571201
103Abnormal finger flexion creases (HP:0006143)1.74461641
104Dislocated radial head (HP:0003083)1.73496617
105Striae distensae (HP:0001065)1.73379275
106Vertebral arch anomaly (HP:0008438)1.73032715
107Nemaline bodies (HP:0003798)1.72164465
108Hypoplastic scapulae (HP:0000882)1.71288402
109Aplasia/Hypoplasia of the scapulae (HP:0006713)1.71288402
110Lipoatrophy (HP:0100578)1.70337229
111Natal tooth (HP:0000695)1.69685726
112Short palpebral fissure (HP:0012745)1.69647856
113Pulmonary hypoplasia (HP:0002089)1.68864056
114Hypoplastic ischia (HP:0003175)1.67688370
115Wrist flexion contracture (HP:0001239)1.66792849
116Vertebral fusion (HP:0002948)1.66775552
117Spondylolisthesis (HP:0003302)1.66301548
118Abnormality of the humeroradial joint (HP:0100744)1.66139009
119Abnormality of the septum pellucidum (HP:0007375)1.66134840
120Aortic aneurysm (HP:0004942)1.65849265
121Type 1 muscle fiber predominance (HP:0003803)1.63553631
122Vascular tortuosity (HP:0004948)1.63545367
123Mesomelia (HP:0003027)1.63085136
124Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.62566277
125Abnormality of the radial head (HP:0003995)1.61319616
126Pterygium (HP:0001059)1.60682096
127Muscle stiffness (HP:0003552)1.59847230
128Hypoalphalipoproteinemia (HP:0003233)1.59644569
129Scapular winging (HP:0003691)1.59279427
130Knee flexion contracture (HP:0006380)1.58854294
131Glucose intolerance (HP:0000833)1.58724618
132Acanthosis nigricans (HP:0000956)1.58250579
133Neck muscle weakness (HP:0000467)1.58083417
134Delayed gross motor development (HP:0002194)1.56515789
135Short middle phalanx of the 5th finger (HP:0004220)1.48084752
136Congenital diaphragmatic hernia (HP:0000776)1.42429577
137Abnormality of the ischium (HP:0003174)1.38910534
138Intestinal malrotation (HP:0002566)1.38350584
139Sudden death (HP:0001699)1.37795655
140Ulnar deviation of the wrist (HP:0003049)1.36352948
141Hypoplastic iliac wings (HP:0002866)1.34757929
142Calcaneovalgus deformity (HP:0001848)1.31480172
143Fibular aplasia (HP:0002990)1.29978804
144Orthostatic hypotension (HP:0001278)1.28996398
145Coronal craniosynostosis (HP:0004440)1.23681798
146Exercise-induced muscle cramps (HP:0003710)1.19474525
147Bell-shaped thorax (HP:0001591)1.18707878
148Narrow mouth (HP:0000160)1.17331284
149Deformed tarsal bones (HP:0008119)1.15520451
150Soft skin (HP:0000977)1.14699239
151Asymmetry of the thorax (HP:0001555)1.11192786
152Neonatal short-limb short stature (HP:0008921)1.10012239
153Microglossia (HP:0000171)1.09086155
154Neonatal respiratory distress (HP:0002643)1.06078195
155Rocker bottom foot (HP:0001838)1.05989895
156Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.04828506
157Areflexia of lower limbs (HP:0002522)1.04303261
158Hypertensive crisis (HP:0100735)1.04243331
159Myopathic facies (HP:0002058)1.02245763
160Abnormal glucose tolerance (HP:0001952)1.01641793
161Hip contracture (HP:0003273)1.00443870
162Bone cyst (HP:0012062)1.00111109
163Ulnar deviation of the hand or of fingers of the hand (HP:0001193)0.99332056

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MKNK25.99040670
2MKNK13.81573046
3LIMK13.28332990
4FGFR43.12139370
5VRK22.61114817
6EIF2AK32.30719293
7MAP3K122.14005673
8MUSK14.2867045
9TGFBR21.89985906
10MOS1.84454329
11EPHA31.82922095
12BMX1.82743999
13STK161.82319683
14TAF11.66294208
15PIK3CG1.62479495
16MYLK1.52116863
17EIF2AK11.42964112
18PAK41.37437540
19EPHB11.31375890
20DDR21.27759905
21PIM21.25124340
22NUAK11.21495411
23ILK1.15005164
24PDK21.13074652
25EIF2AK21.01360107
26NEK60.99569528
27CCNB10.93774697
28NEK10.92727943
29MAPKAPK30.89354760
30PRKD20.84893880
31DYRK1A0.81709803
32PRPF4B0.79231846
33DAPK10.77686689
34PBK0.76965899
35ERBB40.74265357
36BCKDK0.72974348
37PLK30.71395222
38FGFR30.69851383
39MAP3K70.66733395
40HIPK20.66170979
41PAK30.64338308
42NLK0.64092986
43SMG10.62479228
44FER0.60161800
45DAPK30.59925121
46TRIB30.59698942
47AKT30.59622362
48CDK60.56612791
49MST1R0.55380171
50MAP4K20.54160375
51PTK20.47921105
52MAP3K30.47558769
53ERBB30.47366615
54VRK10.47190364
55TTN0.46374416
56PIM10.46119438
57MAP2K30.45829784
58ALK0.45139465
59BRSK10.43683969
60RIPK10.43489550
61SGK4940.43151150
62SGK2230.43151150
63MAPK130.42496249
64FLT30.42137272
65CAMK40.40492408
66FGFR10.38204712
67STK100.35722260
68CDK150.35134048
69SGK20.34767784
70CDK140.34689624
71FRK0.34208700
72GRK50.34164404
73TAOK10.33220834
74CDK180.32616263
75IRAK10.32335989
76PHKG10.32061998
77PHKG20.32061998
78CDK80.31032344
79CDK11A0.30772494
80RPS6KA40.30345556
81MAPK120.29844633
82CHUK0.29640968
83PAK20.29494982
84SRPK10.29437637
85RAF10.29325399
86MTOR0.29175314
87PKN20.28094383
88TSSK60.27722583
89MARK20.26813580
90TNIK0.26213352
91MAP3K110.25441690
92EPHB20.24918567
93CAMK2B0.24620268
94TAOK20.24432154
95AKT20.24313950
96MAPK70.24286009
97MAP2K10.24271661
98SGK30.23276295
99ERN10.23149983
100CAMK2G0.22985747
101STK30.22041529
102ROCK10.21217872
103PINK10.20700440
104NEK90.20150921
105CASK0.19307757
106STK390.19120301
107SIK10.18963514
108PAK10.18945977
109PRKCH0.18732385
110MAP3K10.18228435
111BRD40.17389036
112MAP3K50.16852260
113LATS10.16369672
114ABL10.16268160
115JAK10.15898884
116MET0.15273232
117GRK70.15254310
118PDGFRA0.14638032
119GSK3A0.14545616
120MAPK100.13855386
121MAP3K140.13339326
122TRPM70.13315855
123CAMK2D0.13243584
124BRSK20.12564535
125CAMK2A0.12147175
126MAP3K60.11257889
127MAPKAPK20.10879022
128INSR0.10751538
129PLK20.10502434
130OBSCN0.10484464
131TBK10.10293634
132EGFR0.09916938
133CHEK20.09857505
134RET0.09112112
135PRKACB0.09091486
136STK40.08999331
137PRKD30.08573556
138PTK2B0.08395669
139PRKCG0.08230639
140CDK90.07980862
141ADRBK10.07693320
142LMTK20.07680921
143NME20.07572241
144DYRK20.06695201
145MELK0.06694713
146PRKCE0.06499812
147ROCK20.06431824
148ABL20.05995090
149PRKCD0.04593295
150LATS20.04547396
151UHMK10.03766830
152IKBKE0.03064519
153MAPK10.02513387
154MAPKAPK50.02422369
155MAPK80.02304437
156EPHA20.01966998
157PDGFRB0.01802099
158CDK120.01445909
159SGK10.01420698
160MAP3K100.01176813
161PAK60.01117956

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030503.30107682
2Dorso-ventral axis formation_Homo sapiens_hsa043202.95440182
3MicroRNAs in cancer_Homo sapiens_hsa052062.86358594
4ECM-receptor interaction_Homo sapiens_hsa045122.72145075
5Proteoglycans in cancer_Homo sapiens_hsa052052.49709988
6Acute myeloid leukemia_Homo sapiens_hsa052212.24268257
7Dilated cardiomyopathy_Homo sapiens_hsa054142.23994824
8Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.18443306
9Protein export_Homo sapiens_hsa030602.17124989
10Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.12751854
11Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.08375870
12Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.98646273
13Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.98566574
14TGF-beta signaling pathway_Homo sapiens_hsa043501.97873502
15Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.95296336
16SNARE interactions in vesicular transport_Homo sapiens_hsa041301.94438140
17Adherens junction_Homo sapiens_hsa045201.93203036
18Chronic myeloid leukemia_Homo sapiens_hsa052201.91567332
19Cardiac muscle contraction_Homo sapiens_hsa042601.84708385
20Prion diseases_Homo sapiens_hsa050201.83460529
21Folate biosynthesis_Homo sapiens_hsa007901.81416215
22AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.74371541
23Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.73503541
24Prostate cancer_Homo sapiens_hsa052151.68621128
25Sulfur metabolism_Homo sapiens_hsa009201.63138431
26Nitrogen metabolism_Homo sapiens_hsa009101.56779496
27Viral myocarditis_Homo sapiens_hsa054161.54578723
28Focal adhesion_Homo sapiens_hsa045101.53583220
29Bladder cancer_Homo sapiens_hsa052191.53313055
30RNA polymerase_Homo sapiens_hsa030201.51287824
31Basal transcription factors_Homo sapiens_hsa030221.50782137
32Malaria_Homo sapiens_hsa051441.44814489
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.40897539
34Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.40349845
35Notch signaling pathway_Homo sapiens_hsa043301.39765166
36Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.38118140
37Thyroid cancer_Homo sapiens_hsa052161.37076865
38Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.36419160
39Propanoate metabolism_Homo sapiens_hsa006401.33919787
40Pancreatic cancer_Homo sapiens_hsa052121.28266651
41Amoebiasis_Homo sapiens_hsa051461.27926987
42* Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.26321302
432-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.22242605
44MAPK signaling pathway_Homo sapiens_hsa040101.22145788
45Central carbon metabolism in cancer_Homo sapiens_hsa052301.20798365
46Hippo signaling pathway_Homo sapiens_hsa043901.19314163
47Salmonella infection_Homo sapiens_hsa051321.19138494
48Mineral absorption_Homo sapiens_hsa049781.18591647
49p53 signaling pathway_Homo sapiens_hsa041151.14838003
50Transcriptional misregulation in cancer_Homo sapiens_hsa052021.12311593
51Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.11644397
52Hepatitis B_Homo sapiens_hsa051611.11583432
53Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.09901711
54Complement and coagulation cascades_Homo sapiens_hsa046101.09551706
55Adipocytokine signaling pathway_Homo sapiens_hsa049201.05155275
56Small cell lung cancer_Homo sapiens_hsa052221.04303154
57Pyruvate metabolism_Homo sapiens_hsa006201.04227403
58Thyroid hormone synthesis_Homo sapiens_hsa049181.03431012
59Melanoma_Homo sapiens_hsa052181.03057634
60Vitamin B6 metabolism_Homo sapiens_hsa007501.02704878
61Selenocompound metabolism_Homo sapiens_hsa004501.00916093
62Regulation of actin cytoskeleton_Homo sapiens_hsa048101.00520022
63Primary bile acid biosynthesis_Homo sapiens_hsa001201.00285860
64ErbB signaling pathway_Homo sapiens_hsa040120.99900632
65Renal cell carcinoma_Homo sapiens_hsa052110.99791394
66PI3K-Akt signaling pathway_Homo sapiens_hsa041510.99031422
67Shigellosis_Homo sapiens_hsa051310.98005295
68FoxO signaling pathway_Homo sapiens_hsa040680.97608174
69Estrogen signaling pathway_Homo sapiens_hsa049150.95180688
70African trypanosomiasis_Homo sapiens_hsa051430.95038008
71Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.94892739
72Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.94383235
73Glioma_Homo sapiens_hsa052140.94054840
74Endometrial cancer_Homo sapiens_hsa052130.93145497
75Thyroid hormone signaling pathway_Homo sapiens_hsa049190.92854031
76Rap1 signaling pathway_Homo sapiens_hsa040150.92457211
77Arginine and proline metabolism_Homo sapiens_hsa003300.91668731
78Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.91636670
79Hedgehog signaling pathway_Homo sapiens_hsa043400.90557160
80Platelet activation_Homo sapiens_hsa046110.90180694
81TNF signaling pathway_Homo sapiens_hsa046680.90115780
82Circadian rhythm_Homo sapiens_hsa047100.89656619
83Colorectal cancer_Homo sapiens_hsa052100.88914532
84Tight junction_Homo sapiens_hsa045300.87623265
85Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.87365411
86Leukocyte transendothelial migration_Homo sapiens_hsa046700.85950858
87Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.85112384
88Pyrimidine metabolism_Homo sapiens_hsa002400.84037085
89Pathways in cancer_Homo sapiens_hsa052000.79337841
90Axon guidance_Homo sapiens_hsa043600.79273620
91HTLV-I infection_Homo sapiens_hsa051660.78437470
92Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.78436777
93Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.77715202
94Cocaine addiction_Homo sapiens_hsa050300.77103736
95Toxoplasmosis_Homo sapiens_hsa051450.76123500
96Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.75548189
97Wnt signaling pathway_Homo sapiens_hsa043100.75447348
98Nucleotide excision repair_Homo sapiens_hsa034200.74840617
99Long-term potentiation_Homo sapiens_hsa047200.74809655
100Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.74383583
101Neurotrophin signaling pathway_Homo sapiens_hsa047220.74339336
102NOD-like receptor signaling pathway_Homo sapiens_hsa046210.73490102
103Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.73272734
104Gap junction_Homo sapiens_hsa045400.72379825
105Pentose phosphate pathway_Homo sapiens_hsa000300.72242113
106GnRH signaling pathway_Homo sapiens_hsa049120.70594954
107Glucagon signaling pathway_Homo sapiens_hsa049220.70139577
108Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.68123097
109Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.66758635
110Arginine biosynthesis_Homo sapiens_hsa002200.66112963
111Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.64551904
112cAMP signaling pathway_Homo sapiens_hsa040240.64522979
113Insulin resistance_Homo sapiens_hsa049310.63959498
114Biosynthesis of amino acids_Homo sapiens_hsa012300.63414997
115HIF-1 signaling pathway_Homo sapiens_hsa040660.61882858
116Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.60041565
117Melanogenesis_Homo sapiens_hsa049160.59071406
118Oxytocin signaling pathway_Homo sapiens_hsa049210.57512364
119Alzheimers disease_Homo sapiens_hsa050100.57251256
120Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.57184554
121Parkinsons disease_Homo sapiens_hsa050120.56689316
122Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.55952963
123Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.55509436
124Huntingtons disease_Homo sapiens_hsa050160.53765494
125Pertussis_Homo sapiens_hsa051330.52926391
126Ras signaling pathway_Homo sapiens_hsa040140.52479927
127Salivary secretion_Homo sapiens_hsa049700.50493053
128Protein digestion and absorption_Homo sapiens_hsa049740.49229968
129Glutathione metabolism_Homo sapiens_hsa004800.49155888
130Osteoclast differentiation_Homo sapiens_hsa043800.48558285
131Aldosterone synthesis and secretion_Homo sapiens_hsa049250.48457634
132Hepatitis C_Homo sapiens_hsa051600.47824214
133Prolactin signaling pathway_Homo sapiens_hsa049170.46444336
134Cholinergic synapse_Homo sapiens_hsa047250.46358478
135cGMP-PKG signaling pathway_Homo sapiens_hsa040220.46334830
136Apoptosis_Homo sapiens_hsa042100.46222772
137Fatty acid elongation_Homo sapiens_hsa000620.45522152
138Non-homologous end-joining_Homo sapiens_hsa034500.44641407
139Leishmaniasis_Homo sapiens_hsa051400.44150492
140Non-small cell lung cancer_Homo sapiens_hsa052230.43952867
141Purine metabolism_Homo sapiens_hsa002300.43669002
142Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.43435292
143Endocytosis_Homo sapiens_hsa041440.43037519
144B cell receptor signaling pathway_Homo sapiens_hsa046620.41906387
145Carbon metabolism_Homo sapiens_hsa012000.40841555
146Phospholipase D signaling pathway_Homo sapiens_hsa040720.40769249
147RNA transport_Homo sapiens_hsa030130.39529211
148Galactose metabolism_Homo sapiens_hsa000520.39378706
149Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.39168767
150Regulation of autophagy_Homo sapiens_hsa041400.38988578
151Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.38963607
152Starch and sucrose metabolism_Homo sapiens_hsa005000.38641416
153Legionellosis_Homo sapiens_hsa051340.38539251
154Calcium signaling pathway_Homo sapiens_hsa040200.37506336
155Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.33483354
156Basal cell carcinoma_Homo sapiens_hsa052170.31315306
157Fructose and mannose metabolism_Homo sapiens_hsa000510.30214499
158Cell cycle_Homo sapiens_hsa041100.29740889
159Sulfur relay system_Homo sapiens_hsa041220.29195696
160Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.27543980
161Oxidative phosphorylation_Homo sapiens_hsa001900.24466363
162Cyanoamino acid metabolism_Homo sapiens_hsa004600.24037808
163One carbon pool by folate_Homo sapiens_hsa006700.23520079
164Vascular smooth muscle contraction_Homo sapiens_hsa042700.23303135

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »