MYH1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcoplasmic reticulum calcium ion transport (GO:0070296)9.69575716
2skeletal muscle fiber development (GO:0048741)9.20158102
3actin filament-based movement (GO:0030048)8.45633183
4skeletal muscle adaptation (GO:0043501)8.10648362
5myotube cell development (GO:0014904)7.79108047
6cytidine metabolic process (GO:0046087)7.67006802
7cytidine catabolic process (GO:0006216)7.67006802
8cytidine deamination (GO:0009972)7.67006802
9pyrimidine ribonucleoside catabolic process (GO:0046133)7.16173818
10striated muscle contraction (GO:0006941)6.75023268
11negative regulation of potassium ion transmembrane transporter activity (GO:1901017)6.67004805
12sarcomere organization (GO:0045214)6.52128951
13skeletal muscle tissue regeneration (GO:0043403)6.11643830
14response to stimulus involved in regulation of muscle adaptation (GO:0014874)5.99666332
15myofibril assembly (GO:0030239)5.65510101
16response to inactivity (GO:0014854)5.61136014
17striated muscle atrophy (GO:0014891)5.55095468
18* muscle contraction (GO:0006936)5.51099707
19positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)5.49779204
20response to muscle activity (GO:0014850)5.46457194
21muscle fiber development (GO:0048747)5.19799069
22regulation of actin filament-based movement (GO:1903115)5.18892177
23negative regulation of potassium ion transmembrane transport (GO:1901380)5.09296587
24creatine metabolic process (GO:0006600)4.99633612
25* muscle system process (GO:0003012)4.89968691
26keratinization (GO:0031424)4.86230472
27positive regulation of myotube differentiation (GO:0010831)4.84177239
28regulation of skeletal muscle cell differentiation (GO:2001014)4.78945170
29muscle atrophy (GO:0014889)4.78436666
30muscle cell cellular homeostasis (GO:0046716)4.77500039
31actomyosin structure organization (GO:0031032)4.76524207
32striated muscle adaptation (GO:0014888)4.67390320
33regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.65709177
34glycogen catabolic process (GO:0005980)4.65604636
35positive regulation of mitochondrial calcium ion concentration (GO:0051561)4.62458634
36myoblast fusion (GO:0007520)4.61180190
37regulation of cell communication by electrical coupling (GO:0010649)4.54451009
38cardiac muscle hypertrophy (GO:0003300)4.50010267
39regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.47466807
40NADH metabolic process (GO:0006734)4.39001836
41glucan catabolic process (GO:0009251)4.35040534
42muscle cell fate commitment (GO:0042693)4.34664799
43glycogen biosynthetic process (GO:0005978)4.34444957
44glucan biosynthetic process (GO:0009250)4.34444957
45fructose metabolic process (GO:0006000)4.29767434
46striated muscle hypertrophy (GO:0014897)4.29025241
47myotube differentiation (GO:0014902)4.22298945
48syncytium formation by plasma membrane fusion (GO:0000768)4.20831245
49syncytium formation (GO:0006949)4.12774695
50carnitine shuttle (GO:0006853)4.05607192
51muscle organ development (GO:0007517)4.05123444
52regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.03872096
53positive regulation of calcium ion transmembrane transporter activity (GO:1901021)4.02973618
54cellular polysaccharide catabolic process (GO:0044247)4.00657645
55striated muscle cell development (GO:0055002)4.00569735
56muscle structure development (GO:0061061)3.99026369
57negative regulation of muscle hypertrophy (GO:0014741)3.97534726
58polysaccharide catabolic process (GO:0000272)3.96558871
59hemidesmosome assembly (GO:0031581)3.95778483
60regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.93946751
61skeletal muscle tissue development (GO:0007519)3.92917037
62negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.92793150
63muscle hypertrophy (GO:0014896)3.85975338
64negative regulation of protein localization to cell surface (GO:2000009)3.84210811
65muscle tissue morphogenesis (GO:0060415)3.82392718
66muscle adaptation (GO:0043500)3.77220609
67regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.75339792
68cardiac muscle contraction (GO:0060048)3.73616734
69gluconeogenesis (GO:0006094)3.71657199
70muscle organ morphogenesis (GO:0048644)3.61489231
71positive regulation of myoblast differentiation (GO:0045663)3.58599554
722-oxoglutarate metabolic process (GO:0006103)3.57484066
73heart process (GO:0003015)3.53899003
74heart contraction (GO:0060047)3.53899003
75glycogen metabolic process (GO:0005977)3.53638247
76regulation of relaxation of muscle (GO:1901077)3.52194508
77negative regulation of calcium ion transmembrane transport (GO:1903170)3.50562932
78negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.50562932
79cardiac muscle tissue morphogenesis (GO:0055008)3.48178389
80purine nucleotide salvage (GO:0032261)3.47532352
81cellular glucan metabolic process (GO:0006073)3.46359259
82glucan metabolic process (GO:0044042)3.46359259
83muscle cell development (GO:0055001)3.45411407
84cellular carbohydrate catabolic process (GO:0044275)3.44474436
85fatty acid transmembrane transport (GO:1902001)3.44452124
86adult heart development (GO:0007512)3.43316873
87regulation of myoblast differentiation (GO:0045661)3.42705419
88striated muscle tissue development (GO:0014706)3.41650457
89regulation of acyl-CoA biosynthetic process (GO:0050812)3.41340831
90negative regulation of muscle contraction (GO:0045932)3.41082387
91neuronal action potential propagation (GO:0019227)3.40082333
92positive regulation of cation channel activity (GO:2001259)3.34765702
93hexose biosynthetic process (GO:0019319)3.32488399
94negative regulation of heart growth (GO:0061117)3.31728363
95negative regulation of cardiac muscle tissue growth (GO:0055022)3.31728363
96response to activity (GO:0014823)3.29945917
97neuromuscular synaptic transmission (GO:0007274)3.29250837
98regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.28189443
99cardiac muscle cell development (GO:0055013)3.28040507
100cardiac myofibril assembly (GO:0055003)3.26660608
101cardiac muscle adaptation (GO:0014887)3.23977868
102cardiac muscle hypertrophy in response to stress (GO:0014898)3.23977868
103muscle hypertrophy in response to stress (GO:0003299)3.23977868
104neuromuscular junction development (GO:0007528)3.17984410
105regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.17541845
106relaxation of muscle (GO:0090075)3.17469008
107regulation of striated muscle contraction (GO:0006942)3.17345921
108negative regulation of cell size (GO:0045792)3.12511459
109IMP metabolic process (GO:0046040)3.11894374
110regulation of calcium ion transmembrane transport (GO:1903169)3.08509907
111regulation of calcium ion transmembrane transporter activity (GO:1901019)3.08509907
112negative regulation of skeletal muscle tissue development (GO:0048642)3.08142474
113regulation of cofactor metabolic process (GO:0051193)3.06328812
114regulation of coenzyme metabolic process (GO:0051196)3.06328812
115regulation of sarcomere organization (GO:0060297)3.02788655
116regulation of myotube differentiation (GO:0010830)3.00689496
117desmosome organization (GO:0002934)2.99933625
118carnitine transmembrane transport (GO:1902603)2.97582654
119regulation of membrane repolarization (GO:0060306)2.93715160
120regulation of pseudopodium assembly (GO:0031272)2.93629536
121regulation of p38MAPK cascade (GO:1900744)2.91589461
122tricarboxylic acid cycle (GO:0006099)2.90135769
123negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.90044094
124skeletal muscle cell differentiation (GO:0035914)2.87995966
125muscle filament sliding (GO:0030049)13.6446937
126actin-myosin filament sliding (GO:0033275)13.6446937
127regulation of skeletal muscle contraction (GO:0014819)12.1871900
128skeletal muscle contraction (GO:0003009)11.4693472
129actin-mediated cell contraction (GO:0070252)11.1942495
130plasma membrane repair (GO:0001778)10.0027891

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human6.90080450
2BP1_19119308_ChIP-ChIP_Hs578T_Human5.97364375
3EZH2_22144423_ChIP-Seq_EOC_Human4.58860993
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.73827268
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.44964191
6ESR1_20079471_ChIP-ChIP_T-47D_Human3.22697058
7ZNF263_19887448_ChIP-Seq_K562_Human2.68950289
8RARG_19884340_ChIP-ChIP_MEFs_Mouse2.68679049
9TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.44086779
10ESR1_21235772_ChIP-Seq_MCF-7_Human2.44078866
11ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.38586279
12TBX20_22080862_ChIP-Seq_HEART_Mouse2.28247092
13TBX20_22328084_ChIP-Seq_HEART_Mouse2.28247092
14RBPJ_22232070_ChIP-Seq_NCS_Mouse2.21775836
15ESR2_21235772_ChIP-Seq_MCF-7_Human2.13788409
16P63_26484246_Chip-Seq_KERATINOCYTES_Human1.95472214
17THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.92134365
18ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.87031658
19CTCF_27219007_Chip-Seq_Bcells_Human1.80254405
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.79040719
21TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.78498406
22CDX2_19796622_ChIP-Seq_MESCs_Mouse1.74749654
23CLOCK_20551151_ChIP-Seq_293T_Human1.72755372
24NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.68988241
25EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.67886375
26STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.63216868
27GATA4_21415370_ChIP-Seq_HL-1_Mouse1.63077222
28STAT6_21828071_ChIP-Seq_BEAS2B_Human1.62501091
29BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.58677196
30DNAJC2_21179169_ChIP-ChIP_NT2_Human1.54293438
31RACK7_27058665_Chip-Seq_MCF-7_Human1.50561322
32TRIM28_21343339_ChIP-Seq_HEK293_Human1.49714826
33CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.49636306
34CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.46914798
35ZFP281_18757296_ChIP-ChIP_E14_Mouse1.46104204
36ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.45595797
37MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.45527990
38LXR_22292898_ChIP-Seq_THP-1_Human1.45466123
39NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.44915974
40RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.42321102
41AR_21572438_ChIP-Seq_LNCaP_Human1.41387509
42PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.41264579
43CTCF_21964334_ChIP-Seq_BJAB-B_Human1.39652119
44NFIB_24661679_ChIP-Seq_LUNG_Mouse1.38679122
45UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.35209740
46TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.33384349
47KDM2B_26808549_Chip-Seq_DND41_Human1.32942135
48SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.30968450
49PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.29107535
50SUZ12_27294783_Chip-Seq_NPCs_Mouse1.25961958
51FOXH1_21741376_ChIP-Seq_ESCs_Human1.25719851
52KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.25060457
53ZNF274_21170338_ChIP-Seq_K562_Hela1.24393488
54SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.23411838
55ATF3_27146783_Chip-Seq_COLON_Human1.22548979
56IGF1R_20145208_ChIP-Seq_DFB_Human1.22067572
57SA1_27219007_Chip-Seq_Bcells_Human1.21727959
58KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.21355440
59CJUN_26792858_Chip-Seq_BT549_Human1.21260611
60CRX_20693478_ChIP-Seq_RETINA_Mouse1.21135964
61P300_27058665_Chip-Seq_ZR-75-30cells_Human1.20926008
62PCGF2_27294783_Chip-Seq_ESCs_Mouse1.20793607
63EZH2_27294783_Chip-Seq_NPCs_Mouse1.18177122
64EP300_21415370_ChIP-Seq_HL-1_Mouse1.17654216
65ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.17422403
66FLI1_27457419_Chip-Seq_LIVER_Mouse1.17220479
67TP63_22573176_ChIP-Seq_HFKS_Human1.15938091
68NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.15855690
69SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.15219262
70YY1_22570637_ChIP-Seq_MALME-3M_Human1.14985131
71CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.13456139
72OCT4_21477851_ChIP-Seq_ESCs_Mouse1.12502494
73CTCF_21964334_Chip-Seq_Bcells_Human1.12301619
74PPARA_22158963_ChIP-Seq_LIVER_Mouse1.12284165
75SMC1_22415368_ChIP-Seq_MEFs_Mouse1.11938825
76LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.11493985
77BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.10743693
78ELK3_25401928_ChIP-Seq_HUVEC_Human1.09820059
79SOX9_24532713_ChIP-Seq_HFSC_Mouse1.09051877
80TP53_20018659_ChIP-ChIP_R1E_Mouse1.08953883
81SA1_27219007_Chip-Seq_ERYTHROID_Human1.08537969
82TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08498401
83ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.07027883
84CTCF_27219007_Chip-Seq_ERYTHROID_Human1.05829430
85MYC_27129775_Chip-Seq_CORNEA_Mouse1.05307975
86P68_20966046_ChIP-Seq_HELA_Human1.04124562
87E2F1_20622854_ChIP-Seq_HELA_Human1.03352146
88KDM2B_26808549_Chip-Seq_SUP-B15_Human1.02902534
89GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.02864985
90P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.02363173
91ERG_21242973_ChIP-ChIP_JURKAT_Human1.02111794
92ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.01734726
93EGR1_19032775_ChIP-ChIP_M12_Human1.01190531
94EZH2_27294783_Chip-Seq_ESCs_Mouse1.01088993
95WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.00936943
96HIF1A_21447827_ChIP-Seq_MCF-7_Human1.00539724
97RARB_27405468_Chip-Seq_BRAIN_Mouse1.00504427
98SMC3_22415368_ChIP-Seq_MEFs_Mouse1.00147171
99RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99475337
100GBX2_23144817_ChIP-Seq_PC3_Human0.99136516
101GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.98307431
102STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.97066068
103SOX2_21211035_ChIP-Seq_LN229_Gbm0.96435810
104GATA1_19941827_ChIP-Seq_MEL_Mouse0.96182669
105* OCT4_20526341_ChIP-Seq_ESCs_Human0.96064615
106CBX2_27304074_Chip-Seq_ESCs_Mouse0.95787577
107RUNX1_27514584_Chip-Seq_MCF-7_Human0.95057889
108NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.94561379
109NRF2_20460467_ChIP-Seq_MEFs_Mouse0.94561379
110CREB1_26743006_Chip-Seq_LNCaP_Human0.94321146
111ER_23166858_ChIP-Seq_MCF-7_Human0.94011237
112VDR_22108803_ChIP-Seq_LS180_Human0.93826384
113TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.93475262
114TCF7_22412390_ChIP-Seq_EML_Mouse0.92863315
115PPAR_26484153_Chip-Seq_NCI-H1993_Human0.92855059
116SPI1_20517297_ChIP-Seq_HL60_Human0.91202641
117KDM2B_26808549_Chip-Seq_K562_Human0.91167185
118ELF1_20517297_ChIP-Seq_JURKAT_Human0.90983660
119SUZ12_27294783_Chip-Seq_ESCs_Mouse0.90469338
120DROSHA_22980978_ChIP-Seq_HELA_Human0.89816291
121NANOG_20526341_ChIP-Seq_ESCs_Human0.89362949
122EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.89218779
123CSB_26484114_Chip-Seq_FIBROBLAST_Human0.87760080
124CEBPB_22108803_ChIP-Seq_LS180_Human0.87729216
125BCL6_27268052_Chip-Seq_Bcells_Human0.86629265
126SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.86134709
127GATA6_21074721_ChIP-Seq_CACO-2_Human0.85783511
128P53_22127205_ChIP-Seq_FIBROBLAST_Human0.85436062
129EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.84970481
130RXR_22158963_ChIP-Seq_LIVER_Mouse0.84907884
131GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse0.84904602
132STAT1_20625510_ChIP-Seq_HELA_Human0.84549012
133LXR_22158963_ChIP-Seq_LIVER_Mouse0.84373496
134KLF5_20875108_ChIP-Seq_MESCs_Mouse0.84319028
135RXR_22108803_ChIP-Seq_LS180_Human0.83844429
136UBF1/2_26484160_Chip-Seq_HMECs_Human0.83059508
137PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.79563386
138FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.79085839
139PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.78357197
140NR3C1_23031785_ChIP-Seq_PC12_Mouse0.77820868
141CTNNB1_20460455_ChIP-Seq_HCT116_Human0.77616456
142GATA1_19941827_ChIP-Seq_MEL86_Mouse0.76231544
143CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.75560166
144DPY_21335234_ChIP-Seq_ESCs_Mouse0.75091537
145IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.74181561
146CBP_20019798_ChIP-Seq_JUKART_Human0.74181561
147LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.74159137
148SMAD_19615063_ChIP-ChIP_OVARY_Human0.72144943
149FLI1_21867929_ChIP-Seq_TH2_Mouse0.70522215
150SOX2_19829295_ChIP-Seq_ESCs_Human0.70494986
151NANOG_19829295_ChIP-Seq_ESCs_Human0.70494986
152MTF2_20144788_ChIP-Seq_MESCs_Mouse0.70258669
153TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.68338853
154NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.67084498

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000749_muscle_degeneration6.61704962
2MP0004145_abnormal_muscle_electrophysio6.45157517
3MP0000751_myopathy6.01795265
4MP0003646_muscle_fatigue5.20707453
5MP0002106_abnormal_muscle_physiology4.12083290
6* MP0000747_muscle_weakness4.03231242
7MP0002837_dystrophic_cardiac_calcinosis3.69769185
8* MP0000759_abnormal_skeletal_muscle3.69218146
9MP0000750_abnormal_muscle_regeneration3.62188632
10MP0004036_abnormal_muscle_relaxation3.54473874
11MP0004087_abnormal_muscle_fiber3.49824263
12MP0005369_muscle_phenotype3.41224323
13MP0002269_muscular_atrophy3.15801970
14MP0000733_abnormal_muscle_development3.03508872
15MP0005620_abnormal_muscle_contractility2.89592581
16MP0004130_abnormal_muscle_cell2.74837278
17MP0004270_analgesia2.25799581
18MP0005275_abnormal_skin_tensile2.25707629
19MP0004233_abnormal_muscle_weight2.11623012
20MP0005330_cardiomyopathy2.09822935
21MP0002108_abnormal_muscle_morphology1.99062030
22MP0004084_abnormal_cardiac_muscle1.97295860
23MP0002332_abnormal_exercise_endurance1.93978993
24MP0002796_impaired_skin_barrier1.89138971
25MP0003705_abnormal_hypodermis_morpholog1.81717453
26MP0003950_abnormal_plasma_membrane1.79142269
27MP0004185_abnormal_adipocyte_glucose1.69995303
28MP0000579_abnormal_nail_morphology1.63674954
29MP0002971_abnormal_brown_adipose1.61531545
30MP0006036_abnormal_mitochondrial_physio1.43420880
31MP0002972_abnormal_cardiac_muscle1.40112365
32MP0002234_abnormal_pharynx_morphology1.39041508
33MP0001661_extended_life_span1.36248500
34MP0004484_altered_response_of1.34962397
35MP0004215_abnormal_myocardial_fiber1.33227728
36MP0000013_abnormal_adipose_tissue1.29311225
37MP0010630_abnormal_cardiac_muscle1.28911503
38MP0005666_abnormal_adipose_tissue1.27192683
39MP0000762_abnormal_tongue_morphology1.19722334
40MP0005501_abnormal_skin_physiology1.14455605
41MP0005375_adipose_tissue_phenotype1.04351038
42MP0010234_abnormal_vibrissa_follicle1.03879137
43MP0003221_abnormal_cardiomyocyte_apopto0.91699087
44MP0005266_abnormal_metabolism0.90403244
45MP0001544_abnormal_cardiovascular_syste0.89651036
46MP0005385_cardiovascular_system_phenoty0.89651036
47MP0002822_catalepsy0.87547724
48MP0002060_abnormal_skin_morphology0.87416318
49MP0001299_abnormal_eye_distance/0.84350748
50MP0001243_abnormal_dermal_layer0.83657678
51MP0000383_abnormal_hair_follicle0.82377928
52MP0001849_ear_inflammation0.73216927
53MP0004134_abnormal_chest_morphology0.71802171
54MP0003806_abnormal_nucleotide_metabolis0.71558060
55MP0008438_abnormal_cutaneous_collagen0.69249194
56MP0000467_abnormal_esophagus_morphology0.67751107
57MP0000003_abnormal_adipose_tissue0.67613920
58MP0009250_abnormal_appendicular_skeleto0.66921979
59MP0005670_abnormal_white_adipose0.66726783
60MP0010678_abnormal_skin_adnexa0.65860971
61MP0003137_abnormal_impulse_conducting0.65396247
62MP0003566_abnormal_cell_adhesion0.63368621
63MP0000372_irregular_coat_pigmentation0.62841501
64MP0000647_abnormal_sebaceous_gland0.62143076
65MP0000377_abnormal_hair_follicle0.61553301
66MP0002896_abnormal_bone_mineralization0.61064358
67MP0000427_abnormal_hair_cycle0.60968453
68MP0010771_integument_phenotype0.60805553
69MP0004085_abnormal_heartbeat0.59668529
70MP0003879_abnormal_hair_cell0.58545531
71MP0003828_pulmonary_edema0.57007518
72MP0003453_abnormal_keratinocyte_physiol0.55399085
73MP0008961_abnormal_basal_metabolism0.55032742
74MP0003045_fibrosis0.54677431
75MP0004147_increased_porphyrin_level0.54260630
76MP0002254_reproductive_system_inflammat0.53849685
77MP0006138_congestive_heart_failure0.53082904
78MP0004142_abnormal_muscle_tone0.51948838
79MP0001216_abnormal_epidermal_layer0.50362830
80MP0006035_abnormal_mitochondrial_morpho0.48093775
81MP0008569_lethality_at_weaning0.46914356
82MP0002127_abnormal_cardiovascular_syste0.46706160
83MP0000266_abnormal_heart_morphology0.46290241
84MP0003941_abnormal_skin_development0.46287335
85MP0000343_altered_response_to0.45799456
86MP0004043_abnormal_pH_regulation0.43729834
87MP0009931_abnormal_skin_appearance0.43701347
88MP0005083_abnormal_biliary_tract0.42697818
89MP0002734_abnormal_mechanical_nocicepti0.41103955
90MP0005452_abnormal_adipose_tissue0.40729316
91MP0003656_abnormal_erythrocyte_physiolo0.40402396
92MP0002638_abnormal_pupillary_reflex0.40273891
93MP0002098_abnormal_vibrissa_morphology0.40243463
94MP0003385_abnormal_body_wall0.39906521
95MP0008775_abnormal_heart_ventricle0.39892744
96MP0005584_abnormal_enzyme/coenzyme_acti0.39515215
97MP0002078_abnormal_glucose_homeostasis0.39093228
98MP0004947_skin_inflammation0.38253224
99MP0010030_abnormal_orbit_morphology0.37902675
100MP0002128_abnormal_blood_circulation0.37022134
101MP0009672_abnormal_birth_weight0.36813007
102MP0005423_abnormal_somatic_nervous0.36261802
103MP0005535_abnormal_body_temperature0.34992923
104MP0005334_abnormal_fat_pad0.34946156
105MP0005376_homeostasis/metabolism_phenot0.34875081
106MP0002876_abnormal_thyroid_physiology0.34053146
107MP0002877_abnormal_melanocyte_morpholog0.33699660
108MP0003755_abnormal_palate_morphology0.32790727
109MP0005167_abnormal_blood-brain_barrier0.32437077
110MP0005451_abnormal_body_composition0.31597470
111MP0004510_myositis0.31395058
112MP0003567_abnormal_fetal_cardiomyocyte0.31139566
113* MP0002114_abnormal_axial_skeleton0.30858050
114MP0003948_abnormal_gas_homeostasis0.30249604
115MP0001346_abnormal_lacrimal_gland0.29883338
116MP0005166_decreased_susceptibility_to0.29590334
117MP0001943_abnormal_respiration0.29125555
118MP0009780_abnormal_chondrocyte_physiolo0.28779497
119MP0005319_abnormal_enzyme/_coenzyme0.26997702
120MP0000230_abnormal_systemic_arterial0.26681909
121MP0005332_abnormal_amino_acid0.25187788
122MP0004197_abnormal_fetal_growth/weight/0.22105094
123MP0002066_abnormal_motor_capabilities/c0.22027343
124MP0003959_abnormal_lean_body0.21923926
125MP0005165_increased_susceptibility_to0.18592275
126MP0006276_abnormal_autonomic_nervous0.16475000
127MP0005187_abnormal_penis_morphology0.16307087
128MP0009703_decreased_birth_body0.14536575
129MP0002067_abnormal_sensory_capabilities0.13999367
130MP0009115_abnormal_fat_cell0.12244893
131MP0004858_abnormal_nervous_system0.12083695

Predicted human phenotypes

RankGene SetZ-score
1Nemaline bodies (HP:0003798)9.76855725
2Distal arthrogryposis (HP:0005684)8.22577511
3Type 1 muscle fiber predominance (HP:0003803)8.21489445
4Exercise-induced myalgia (HP:0003738)7.53546929
5Myopathic facies (HP:0002058)6.70680803
6Round ear (HP:0100830)6.70534533
7Ulnar deviation of the wrist (HP:0003049)6.44121509
8Exercise-induced muscle cramps (HP:0003710)6.36686222
9Calcaneovalgus deformity (HP:0001848)5.65707472
10Muscle hypertrophy of the lower extremities (HP:0008968)5.48612280
11Calf muscle hypertrophy (HP:0008981)5.25463165
12Muscle fiber splitting (HP:0003555)5.20782822
13Deformed tarsal bones (HP:0008119)5.11050459
14Absent phalangeal crease (HP:0006109)5.08459024
15Difficulty running (HP:0009046)5.00967836
16Hyporeflexia of lower limbs (HP:0002600)4.89442346
17EMG: myopathic abnormalities (HP:0003458)4.40761687
18Abnormal finger flexion creases (HP:0006143)4.25186031
19Abnormality of skeletal muscle fiber size (HP:0012084)4.21803976
20Increased connective tissue (HP:0009025)4.21611947
21Malignant hyperthermia (HP:0002047)4.03196108
22Abnormality of the calf musculature (HP:0001430)4.01767732
23Myoglobinuria (HP:0002913)4.00698051
24Neck muscle weakness (HP:0000467)3.89391911
25Fetal akinesia sequence (HP:0001989)3.69894489
26Frequent falls (HP:0002359)3.67328010
27Increased variability in muscle fiber diameter (HP:0003557)3.61004713
28Muscle stiffness (HP:0003552)3.59705772
29Abnormality of the calcaneus (HP:0008364)3.45483990
30Difficulty climbing stairs (HP:0003551)3.43602979
31Myotonia (HP:0002486)3.39662399
32Rimmed vacuoles (HP:0003805)3.22018506
33Rhabdomyolysis (HP:0003201)3.17776580
34Fatigable weakness (HP:0003473)3.12516749
35Abnormality of the neuromuscular junction (HP:0003398)3.12516749
36Slender build (HP:0001533)3.07988951
37Mildly elevated creatine phosphokinase (HP:0008180)2.89845357
38Subaortic stenosis (HP:0001682)2.82919035
39Abnormality of the left ventricular outflow tract (HP:0011103)2.82919035
40Areflexia of lower limbs (HP:0002522)2.81894554
41Shoulder girdle muscle weakness (HP:0003547)2.81774934
42Pelvic girdle muscle weakness (HP:0003749)2.80483978
43Bulbar palsy (HP:0001283)2.79734076
44Bundle branch block (HP:0011710)2.78378567
45Abnormality of the musculature of the pelvis (HP:0001469)2.70017089
46Abnormality of the hip-girdle musculature (HP:0001445)2.70017089
47Weak cry (HP:0001612)2.65562589
48Spinal rigidity (HP:0003306)2.65472631
49Gowers sign (HP:0003391)2.64570250
50Scapular winging (HP:0003691)2.56382555
51EMG: neuropathic changes (HP:0003445)2.51769414
52Generalized muscle weakness (HP:0003324)2.44703604
53Centrally nucleated skeletal muscle fibers (HP:0003687)2.43390429
54Sudden death (HP:0001699)2.41243453
55Facial diplegia (HP:0001349)2.39756653
56Distal lower limb muscle weakness (HP:0009053)2.39586995
57Metatarsus adductus (HP:0001840)2.38389284
58Hip contracture (HP:0003273)2.34733786
59Asymmetric septal hypertrophy (HP:0001670)2.30180762
60Hyperkalemia (HP:0002153)2.27720600
61Distal lower limb amyotrophy (HP:0008944)2.27076657
62Ulnar deviation of finger (HP:0009465)2.26009434
63Dilated cardiomyopathy (HP:0001644)2.25061438
64Abnormality of the shoulder girdle musculature (HP:0001435)2.22640685
65Popliteal pterygium (HP:0009756)2.22579904
66Muscular dystrophy (HP:0003560)2.08796718
67Hypoplastic ischia (HP:0003175)2.01015747
68Waddling gait (HP:0002515)2.00481762
69Paralysis (HP:0003470)2.00144392
70Limb-girdle muscle atrophy (HP:0003797)2.00140506
71Muscle fiber inclusion bodies (HP:0100299)10.4894255
72Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)10.1791674
73Lipoatrophy (HP:0100578)1.98464030
74Type 2 muscle fiber atrophy (HP:0003554)1.98191991
75Proximal amyotrophy (HP:0007126)1.98137059
76Nonprogressive disorder (HP:0003680)1.95496142
77Limb-girdle muscle weakness (HP:0003325)1.94705352
78Abnormality of placental membranes (HP:0011409)1.93243054
79Amniotic constriction ring (HP:0009775)1.93243054
80Breech presentation (HP:0001623)1.86327364
81Respiratory insufficiency due to muscle weakness (HP:0002747)1.85098205
82Right ventricular cardiomyopathy (HP:0011663)1.83265931
83Abnormality of the foot musculature (HP:0001436)1.81465224
84Muscle fiber atrophy (HP:0100295)1.79287338
85Progressive muscle weakness (HP:0003323)1.78985324
86Trismus (HP:0000211)1.77445055
87Tarsal synostosis (HP:0008368)1.76660207
88Ulnar deviation of the hand or of fingers of the hand (HP:0001193)1.75972173
89Heart block (HP:0012722)1.75850729
90Achilles tendon contracture (HP:0001771)1.75118014
91Abnormality of the ischium (HP:0003174)1.74534414
92Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.71567368
93Lower limb amyotrophy (HP:0007210)1.71029165
94Long clavicles (HP:0000890)1.67467807
95Exercise intolerance (HP:0003546)1.66839024
96Adducted thumb (HP:0001181)1.64992189
97Abnormal atrioventricular conduction (HP:0005150)1.64659147
98Congenital hip dislocation (HP:0001374)1.64081970
99Limited hip movement (HP:0008800)1.60088167
100Abnormality of the Achilles tendon (HP:0005109)1.59862904
101Oligomenorrhea (HP:0000876)1.59309048
102Aplasia of the musculature (HP:0100854)1.58987515
103Synostosis involving bones of the lower limbs (HP:0009138)1.58386617
104Synostosis involving bones of the feet (HP:0009140)1.58386617
105Easy fatigability (HP:0003388)1.57640800
106Ventricular tachycardia (HP:0004756)1.53111209
107Foot dorsiflexor weakness (HP:0009027)1.51390886
108Increased density of long bones (HP:0006392)1.48702654
109Ventricular arrhythmia (HP:0004308)1.40836184
110Ragged-red muscle fibers (HP:0003200)1.37501335
111Abnormality of potassium homeostasis (HP:0011042)1.34811003
112Steppage gait (HP:0003376)1.34787595
113Insulin-resistant diabetes mellitus (HP:0000831)1.31319474
114Increased intramyocellular lipid droplets (HP:0012240)1.28840124

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN9.16372303
2TTN5.71544528
3PIK3CG5.61654350
4PHKG24.32872097
5PHKG14.32872097
6NME14.11891335
7TRIB32.59051323
8MAP2K32.52508353
9NEK12.16223155
10MAP3K72.06686310
11MUSK1.92223306
12DMPK1.80590387
13PDK41.77445185
14PDK31.77445185
15MAPK121.52760056
16PINK11.42288073
17MAP3K31.41376979
18MAPKAPK31.25740234
19MAP2K41.25347212
20MAP2K61.21095297
21MARK11.14437817
22PIK3CA1.13148702
23PDK21.11648606
24EPHB11.02233253
25MOS0.96733512
26BCKDK0.91049112
27CCNB10.89136272
28PKN20.89096934
29TAOK10.88156215
30MAPK110.80493510
31ERN10.80216739
32AKT20.76966385
33LIMK10.76737735
34MAP3K110.72952148
35TRPM70.71577399
36RIPK10.71263076
37ILK0.65848138
38MAP3K130.64953222
39TAOK20.61594453
40MAP2K10.60960706
41CAMK2G0.59239816
42CAMK40.56979086
43ERBB30.54784697
44PRKAA10.54315803
45FER0.51423568
46MST1R0.51411916
47SGK30.48962450
48PRKAA20.48251813
49CAMK2D0.47463135
50PTK60.45460705
51NEK90.45422132
52STK240.45416150
53ZAK0.45383686
54SIK10.42273314
55MAP3K50.41552748
56LATS10.41422643
57CAMK10.40961749
58CAMK2B0.37706771
59MAP3K100.36731564
60SGK20.36385865
61ROCK10.36343999
62LATS20.36159199
63PRKG10.35228298
64MAP3K10.34473561
65MAP3K60.33546375
66RPS6KB10.33545649
67KSR20.31490915
68MARK20.31391178
69SGK10.31068352
70DYRK1B0.30883154
71TBK10.30845976
72LRRK20.30587232
73EEF2K0.29681073
74DDR20.29298426
75MAPK40.28272693
76NLK0.28009727
77MAPK130.27410405
78FGFR40.27248451
79ROCK20.25463655
80PRKACB0.25394523
81RPS6KA30.24505386
82PIM20.24481313
83CDK60.23399593
84PDPK10.22082444
85STK110.21247605
86MAPK70.21103664
87PRKD10.20966173
88FGFR10.20458485
89ICK0.20343503
90MARK30.20208391
91BMX0.20155470
92PKN10.20038824
93PRKACA0.19028145
94FGFR30.17724787
95EPHB20.17685934
96CDK190.17066489
97PDGFRA0.16194246
98EPHA30.15660797
99SGK4940.15247984
100SGK2230.15247984
101TGFBR20.15213600
102RPS6KB20.14336421
103PAK60.13237833
104PRKACG0.12449689
105DAPK20.11728070
106PAK40.11707811
107MTOR0.11029780
108PDK10.10109884
109MAPK100.08852760
110ZAP700.08308547
111RET0.07825173
112RPS6KA10.07507685
113RAF10.07147811
114MAPKAPK20.07085775
115CSNK1D0.06588632
116ARAF0.06374668
117MAPK80.06009633
118TYK20.05756840
119RPS6KC10.05570194
120RPS6KL10.05570194
121GSK3A0.04855082
122PRPF4B0.04349899
123KSR10.02974361
124RPS6KA60.02898883
125GSK3B0.02746476
126MAPK30.02389563
127CAMK2A0.02028196
128MAPK90.01993552
129PTK2B0.01901189
130TIE10.01481584
131PAK10.00335373

Predicted pathways (KEGG)

RankGene SetZ-score
1Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054104.31500931
2Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054124.14502549
3Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.78192483
4Dilated cardiomyopathy_Homo sapiens_hsa054143.76023554
5Cardiac muscle contraction_Homo sapiens_hsa042603.37727058
62-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.94640722
7Starch and sucrose metabolism_Homo sapiens_hsa005002.85591278
8Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.46136158
9Insulin signaling pathway_Homo sapiens_hsa049102.17050456
10Oxytocin signaling pathway_Homo sapiens_hsa049212.15882972
11Glucagon signaling pathway_Homo sapiens_hsa049222.09702787
12Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.07829251
13Insulin resistance_Homo sapiens_hsa049311.99947289
14Carbon metabolism_Homo sapiens_hsa012001.93096445
15Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.81674248
16Propanoate metabolism_Homo sapiens_hsa006401.64763784
17* Tight junction_Homo sapiens_hsa045301.55552533
18Calcium signaling pathway_Homo sapiens_hsa040201.47921776
19Focal adhesion_Homo sapiens_hsa045101.46821336
20Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.45365933
21Adipocytokine signaling pathway_Homo sapiens_hsa049201.45264556
22Biosynthesis of amino acids_Homo sapiens_hsa012301.42509099
23AMPK signaling pathway_Homo sapiens_hsa041521.38819608
24Viral myocarditis_Homo sapiens_hsa054161.34516429
25Galactose metabolism_Homo sapiens_hsa000521.33157098
26Alzheimers disease_Homo sapiens_hsa050101.28853250
27Fatty acid degradation_Homo sapiens_hsa000711.24319091
28Circadian rhythm_Homo sapiens_hsa047101.24226886
29Vascular smooth muscle contraction_Homo sapiens_hsa042701.24131036
30GnRH signaling pathway_Homo sapiens_hsa049121.19063476
31Central carbon metabolism in cancer_Homo sapiens_hsa052301.12975398
32cGMP-PKG signaling pathway_Homo sapiens_hsa040221.07719170
33Parkinsons disease_Homo sapiens_hsa050121.07094638
34Fructose and mannose metabolism_Homo sapiens_hsa000511.06535319
35Pyruvate metabolism_Homo sapiens_hsa006201.05755797
36VEGF signaling pathway_Homo sapiens_hsa043701.04764507
37Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.99952614
38Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.96235877
39Gastric acid secretion_Homo sapiens_hsa049710.93601731
40Proteoglycans in cancer_Homo sapiens_hsa052050.93165484
41Arginine and proline metabolism_Homo sapiens_hsa003300.92408134
42Fatty acid metabolism_Homo sapiens_hsa012120.90367510
43Arginine biosynthesis_Homo sapiens_hsa002200.89360146
44Amoebiasis_Homo sapiens_hsa051460.87470612
45Renin secretion_Homo sapiens_hsa049240.86818077
46HIF-1 signaling pathway_Homo sapiens_hsa040660.85664675
47Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.82830545
48Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.80348890
49Oxidative phosphorylation_Homo sapiens_hsa001900.77664218
50MAPK signaling pathway_Homo sapiens_hsa040100.76244489
51Leukocyte transendothelial migration_Homo sapiens_hsa046700.75804719
52Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.73345415
53ECM-receptor interaction_Homo sapiens_hsa045120.72646222
54Adherens junction_Homo sapiens_hsa045200.71205653
55Pentose phosphate pathway_Homo sapiens_hsa000300.70291292
56Fatty acid biosynthesis_Homo sapiens_hsa000610.69901418
57FoxO signaling pathway_Homo sapiens_hsa040680.68887297
58mTOR signaling pathway_Homo sapiens_hsa041500.67499952
59Regulation of actin cytoskeleton_Homo sapiens_hsa048100.67301421
60Long-term depression_Homo sapiens_hsa047300.67281045
61Platelet activation_Homo sapiens_hsa046110.66865477
62Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.64342013
63Phenylalanine metabolism_Homo sapiens_hsa003600.63872338
64Regulation of autophagy_Homo sapiens_hsa041400.56792703
65Longevity regulating pathway - mammal_Homo sapiens_hsa042110.56621870
66PPAR signaling pathway_Homo sapiens_hsa033200.56189226
67Renal cell carcinoma_Homo sapiens_hsa052110.52060794
68Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51895210
69Insulin secretion_Homo sapiens_hsa049110.46797959
70Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.44217574
71alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.42562815
72Fat digestion and absorption_Homo sapiens_hsa049750.42425535
73Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.42264246
74Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.41420855
75Melanogenesis_Homo sapiens_hsa049160.41357330
76Fatty acid elongation_Homo sapiens_hsa000620.41315617
77Salivary secretion_Homo sapiens_hsa049700.39235327
78Aldosterone synthesis and secretion_Homo sapiens_hsa049250.38696401
79Nitrogen metabolism_Homo sapiens_hsa009100.37837906
80Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.37604831
81Basal cell carcinoma_Homo sapiens_hsa052170.37494725
82Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.37138309
83Linoleic acid metabolism_Homo sapiens_hsa005910.36434699
84Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.36050590
85ABC transporters_Homo sapiens_hsa020100.35782692
86Glioma_Homo sapiens_hsa052140.35353326
87Type II diabetes mellitus_Homo sapiens_hsa049300.35311518
88AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.35215152
89Lysine degradation_Homo sapiens_hsa003100.34610067
90beta-Alanine metabolism_Homo sapiens_hsa004100.33264036
91Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.31468610
92Cholinergic synapse_Homo sapiens_hsa047250.29889733
93Bladder cancer_Homo sapiens_hsa052190.29440572
94Peroxisome_Homo sapiens_hsa041460.29154559
95Acute myeloid leukemia_Homo sapiens_hsa052210.28114268
96Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.27869093
97Tryptophan metabolism_Homo sapiens_hsa003800.27544129
98Circadian entrainment_Homo sapiens_hsa047130.26895045
99cAMP signaling pathway_Homo sapiens_hsa040240.26634369
100Amphetamine addiction_Homo sapiens_hsa050310.26415339
101Tyrosine metabolism_Homo sapiens_hsa003500.24531338
102Salmonella infection_Homo sapiens_hsa051320.23964388
103Toxoplasmosis_Homo sapiens_hsa051450.23214791
104Long-term potentiation_Homo sapiens_hsa047200.21977662
105Huntingtons disease_Homo sapiens_hsa050160.21157849
106Pancreatic secretion_Homo sapiens_hsa049720.20962596
107Purine metabolism_Homo sapiens_hsa002300.20861632
108Neurotrophin signaling pathway_Homo sapiens_hsa047220.20533824
109Histidine metabolism_Homo sapiens_hsa003400.20201587
110Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.20074056
111Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.19019648
112Butanoate metabolism_Homo sapiens_hsa006500.18951004
113Prolactin signaling pathway_Homo sapiens_hsa049170.18827902
114Chronic myeloid leukemia_Homo sapiens_hsa052200.18365541
115Oocyte meiosis_Homo sapiens_hsa041140.18065278
116Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.17123147
117Phototransduction_Homo sapiens_hsa047440.16746500
118Olfactory transduction_Homo sapiens_hsa047400.16370256
119Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.15408777
120Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.14122512
121Phosphatidylinositol signaling system_Homo sapiens_hsa040700.12698879

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