

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cytidine metabolic process (GO:0046087) | 7.44626557 |
| 2 | cytidine catabolic process (GO:0006216) | 7.44626557 |
| 3 | cytidine deamination (GO:0009972) | 7.44626557 |
| 4 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.59819643 |
| 5 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 6.38480545 |
| 6 | DNA deamination (GO:0045006) | 6.31833630 |
| 7 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 5.62701917 |
| 8 | actin nucleation (GO:0045010) | 5.18694428 |
| 9 | positive T cell selection (GO:0043368) | 4.89959135 |
| 10 | positive thymic T cell selection (GO:0045059) | 4.66487884 |
| 11 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.60521724 |
| 12 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.59343083 |
| 13 | negative T cell selection (GO:0043383) | 4.47563901 |
| 14 | T cell migration (GO:0072678) | 4.42101368 |
| 15 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.34435425 |
| 16 | ATP synthesis coupled proton transport (GO:0015986) | 4.34435425 |
| 17 | sequestering of actin monomers (GO:0042989) | 4.33589434 |
| 18 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.32947174 |
| 19 | positive regulation of calcium-mediated signaling (GO:0050850) | 4.29006787 |
| 20 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.05204749 |
| 21 | negative regulation of T cell apoptotic process (GO:0070233) | 4.02868509 |
| 22 | T cell costimulation (GO:0031295) | 3.93727031 |
| 23 | T cell receptor signaling pathway (GO:0050852) | 3.89810612 |
| 24 | lymphocyte costimulation (GO:0031294) | 3.89213713 |
| 25 | cytolysis (GO:0019835) | 3.84689060 |
| 26 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.68693335 |
| 27 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.63502209 |
| 28 | regulation of activation of Janus kinase activity (GO:0010533) | 3.62696819 |
| 29 | respiratory electron transport chain (GO:0022904) | 3.59680927 |
| 30 | protein neddylation (GO:0045116) | 3.58271494 |
| 31 | electron transport chain (GO:0022900) | 3.57253429 |
| 32 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.56313214 |
| 33 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.55621686 |
| 34 | negative thymic T cell selection (GO:0045060) | 3.48373749 |
| 35 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.41260475 |
| 36 | positive regulation of protein homodimerization activity (GO:0090073) | 3.40941602 |
| 37 | regulation of interleukin-8 secretion (GO:2000482) | 3.38976923 |
| 38 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.37907568 |
| 39 | thymic T cell selection (GO:0045061) | 3.36326328 |
| 40 | positive regulation of monocyte chemotaxis (GO:0090026) | 3.35939410 |
| 41 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.33088390 |
| 42 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.30376730 |
| 43 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.29878897 |
| 44 | negative regulation by host of viral transcription (GO:0043922) | 3.26980942 |
| 45 | eosinophil chemotaxis (GO:0048245) | 3.26246476 |
| 46 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.25897981 |
| 47 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.25057190 |
| 48 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.24857153 |
| 49 | macrophage chemotaxis (GO:0048246) | 3.24646323 |
| 50 | T cell selection (GO:0045058) | 3.24472352 |
| 51 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.24159375 |
| 52 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.21188383 |
| 53 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.20542210 |
| 54 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.19066797 |
| 55 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.17906985 |
| 56 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.17112009 |
| 57 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.16584518 |
| 58 | regulation of T cell tolerance induction (GO:0002664) | 3.15581578 |
| 59 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.15370680 |
| 60 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.13976697 |
| 61 | negative regulation of viral genome replication (GO:0045071) | 3.13403110 |
| 62 | regulation of calcium-mediated signaling (GO:0050848) | 3.13115677 |
| 63 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.13015812 |
| 64 | response to interferon-beta (GO:0035456) | 3.12225358 |
| 65 | regulation of chronic inflammatory response (GO:0002676) | 3.12156332 |
| 66 | negative regulation of mast cell activation (GO:0033004) | 3.12037441 |
| 67 | positive regulation of tolerance induction (GO:0002645) | 3.11397401 |
| 68 | cellular response to interleukin-15 (GO:0071350) | 3.11327841 |
| 69 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.11161376 |
| 70 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.07469256 |
| 71 | positive regulation of cell killing (GO:0031343) | 3.07427505 |
| 72 | platelet dense granule organization (GO:0060155) | 3.05616079 |
| 73 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.01728920 |
| 74 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.01728920 |
| 75 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.00681715 |
| 76 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.00681715 |
| 77 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.00681715 |
| 78 | eosinophil migration (GO:0072677) | 2.98757915 |
| 79 | regulation of regulatory T cell differentiation (GO:0045589) | 2.96506247 |
| 80 | lymphocyte chemotaxis (GO:0048247) | 2.92035190 |
| 81 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.90173955 |
| 82 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.88652246 |
| 83 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.88652246 |
| 84 | lymphocyte migration (GO:0072676) | 2.88370921 |
| 85 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.83467906 |
| 86 | chemokine-mediated signaling pathway (GO:0070098) | 2.83358256 |
| 87 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 2.81827894 |
| 88 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.81019983 |
| 89 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.81019983 |
| 90 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.80260016 |
| 91 | regulation of T cell chemotaxis (GO:0010819) | 2.79692113 |
| 92 | positive regulation of T cell chemotaxis (GO:0010820) | 2.79692113 |
| 93 | immunoglobulin mediated immune response (GO:0016064) | 2.79418853 |
| 94 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.79386829 |
| 95 | positive regulation of defense response to virus by host (GO:0002230) | 2.78330763 |
| 96 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.77496122 |
| 97 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.75264138 |
| 98 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.75126174 |
| 99 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.75126174 |
| 100 | positive regulation of lymphocyte migration (GO:2000403) | 2.73989810 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.45574447 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.76367707 |
| 3 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.74312237 |
| 4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.48547684 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.47014993 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.17284765 |
| 7 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.12654205 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.03411164 |
| 9 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.95279209 |
| 10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.59734540 |
| 11 | MYB_26560356_Chip-Seq_TH2_Human | 2.44232684 |
| 12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.21412396 |
| 13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.21196608 |
| 14 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.19781055 |
| 15 | VDR_22108803_ChIP-Seq_LS180_Human | 2.12582286 |
| 16 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.96106166 |
| 17 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.94372189 |
| 18 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.93072586 |
| 19 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.92975373 |
| 20 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.88642210 |
| 21 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.87704945 |
| 22 | GATA3_26560356_Chip-Seq_TH2_Human | 1.83828646 |
| 23 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.82523921 |
| 24 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.80892368 |
| 25 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.79149776 |
| 26 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.69174343 |
| 27 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.65763480 |
| 28 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.63233826 |
| 29 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.62052994 |
| 30 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.55443799 |
| 31 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.53022369 |
| 32 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.52852008 |
| 33 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.44929693 |
| 34 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.44307851 |
| 35 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.42403188 |
| 36 | AR_20517297_ChIP-Seq_VCAP_Human | 1.41054277 |
| 37 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.40523221 |
| 38 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.38585158 |
| 39 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.36503472 |
| 40 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.36062019 |
| 41 | MYB_26560356_Chip-Seq_TH1_Human | 1.35395946 |
| 42 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.34629148 |
| 43 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.34629148 |
| 44 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.33890564 |
| 45 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.32371137 |
| 46 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.31838760 |
| 47 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.30208694 |
| 48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.30177714 |
| 49 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.27255874 |
| 50 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.27255874 |
| 51 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.26380948 |
| 52 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.25762749 |
| 53 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.24089267 |
| 54 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.23786042 |
| 55 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.23611479 |
| 56 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.23217723 |
| 57 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.22499898 |
| 58 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.20981773 |
| 59 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.20865648 |
| 60 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.18731794 |
| 61 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.17960784 |
| 62 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.17729316 |
| 63 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.17603064 |
| 64 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.16958316 |
| 65 | P300_19829295_ChIP-Seq_ESCs_Human | 1.14762457 |
| 66 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.14297111 |
| 67 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.12913185 |
| 68 | EWS_26573619_Chip-Seq_HEK293_Human | 1.12272945 |
| 69 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.11761580 |
| 70 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.11630262 |
| 71 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.11196269 |
| 72 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.11196269 |
| 73 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.11017014 |
| 74 | NCOR_22424771_ChIP-Seq_293T_Human | 1.09671654 |
| 75 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.08767080 |
| 76 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.07806374 |
| 77 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.07638344 |
| 78 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.06558978 |
| 79 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.03894295 |
| 80 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.03119127 |
| 81 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.02919897 |
| 82 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.02818521 |
| 83 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.02806338 |
| 84 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.02582279 |
| 85 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.01320300 |
| 86 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.00973105 |
| 87 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.00804306 |
| 88 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.00034434 |
| 89 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.99018134 |
| 90 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.97919026 |
| 91 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.97754463 |
| 92 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.97530247 |
| 93 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.97112672 |
| 94 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.96986805 |
| 95 | GATA3_26560356_Chip-Seq_TH1_Human | 0.96635116 |
| 96 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.96213602 |
| 97 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 0.95430496 |
| 98 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.94386376 |
| 99 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.92952633 |
| 100 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.92152990 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 6.33185610 |
| 2 | MP0009785_altered_susceptibility_to | 3.91744100 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.83182099 |
| 4 | MP0003763_abnormal_thymus_physiology | 3.06229168 |
| 5 | MP0002166_altered_tumor_susceptibility | 2.78779807 |
| 6 | MP0009333_abnormal_splenocyte_physiolog | 2.45230224 |
| 7 | MP0001800_abnormal_humoral_immune | 2.44377242 |
| 8 | MP0002138_abnormal_hepatobiliary_system | 2.34861865 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.32168514 |
| 10 | MP0009379_abnormal_foot_pigmentation | 2.29016607 |
| 11 | MP0002102_abnormal_ear_morphology | 2.22744112 |
| 12 | MP0005025_abnormal_response_to | 2.20494546 |
| 13 | MP0002006_tumorigenesis | 2.16493654 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.11701895 |
| 15 | MP0000685_abnormal_immune_system | 2.11546541 |
| 16 | MP0004147_increased_porphyrin_level | 2.10639796 |
| 17 | MP0001819_abnormal_immune_cell | 2.08237951 |
| 18 | MP0002148_abnormal_hypersensitivity_rea | 2.06184145 |
| 19 | MP0003866_abnormal_defecation | 2.03402762 |
| 20 | MP0002723_abnormal_immune_serum | 2.01587819 |
| 21 | MP0003724_increased_susceptibility_to | 1.90388287 |
| 22 | MP0002452_abnormal_antigen_presenting | 1.89618974 |
| 23 | MP0005084_abnormal_gallbladder_morpholo | 1.78437762 |
| 24 | MP0001790_abnormal_immune_system | 1.78196209 |
| 25 | MP0005387_immune_system_phenotype | 1.78196209 |
| 26 | MP0006054_spinal_hemorrhage | 1.78139744 |
| 27 | MP0010155_abnormal_intestine_physiology | 1.77151224 |
| 28 | MP0001873_stomach_inflammation | 1.74124743 |
| 29 | MP0006082_CNS_inflammation | 1.67794179 |
| 30 | MP0003880_abnormal_central_pattern | 1.63945915 |
| 31 | MP0003448_altered_tumor_morphology | 1.59960102 |
| 32 | MP0002933_joint_inflammation | 1.56468895 |
| 33 | MP0000716_abnormal_immune_system | 1.51510892 |
| 34 | MP0006072_abnormal_retinal_apoptosis | 1.50310761 |
| 35 | MP0008872_abnormal_physiological_respon | 1.49562513 |
| 36 | MP0003283_abnormal_digestive_organ | 1.43147775 |
| 37 | MP0002398_abnormal_bone_marrow | 1.41289227 |
| 38 | MP0002419_abnormal_innate_immunity | 1.39785481 |
| 39 | MP0000372_irregular_coat_pigmentation | 1.34947449 |
| 40 | MP0001845_abnormal_inflammatory_respons | 1.34580053 |
| 41 | MP0009764_decreased_sensitivity_to | 1.33820055 |
| 42 | MP0005645_abnormal_hypothalamus_physiol | 1.31072683 |
| 43 | MP0010386_abnormal_urinary_bladder | 1.30990587 |
| 44 | MP0003878_abnormal_ear_physiology | 1.28061157 |
| 45 | MP0005377_hearing/vestibular/ear_phenot | 1.28061157 |
| 46 | MP0003045_fibrosis | 1.26667021 |
| 47 | MP0003011_delayed_dark_adaptation | 1.26400040 |
| 48 | MP0000858_altered_metastatic_potential | 1.26276380 |
| 49 | MP0003252_abnormal_bile_duct | 1.25221449 |
| 50 | MP0002405_respiratory_system_inflammati | 1.25218724 |
| 51 | MP0001919_abnormal_reproductive_system | 1.15434691 |
| 52 | MP0000703_abnormal_thymus_morphology | 1.14236567 |
| 53 | MP0002722_abnormal_immune_system | 1.14013777 |
| 54 | MP0004145_abnormal_muscle_electrophysio | 1.13444439 |
| 55 | MP0000689_abnormal_spleen_morphology | 1.12236923 |
| 56 | MP0002234_abnormal_pharynx_morphology | 1.11974260 |
| 57 | MP0008875_abnormal_xenobiotic_pharmacok | 1.10168032 |
| 58 | MP0008995_early_reproductive_senescence | 1.10053582 |
| 59 | MP0005551_abnormal_eye_electrophysiolog | 1.09621552 |
| 60 | MP0005083_abnormal_biliary_tract | 1.07670076 |
| 61 | MP0001188_hyperpigmentation | 1.07456297 |
| 62 | MP0002429_abnormal_blood_cell | 1.07411803 |
| 63 | MP0008469_abnormal_protein_level | 1.05813009 |
| 64 | MP0002837_dystrophic_cardiac_calcinosis | 1.04715683 |
| 65 | MP0003137_abnormal_impulse_conducting | 1.04554939 |
| 66 | MP0003436_decreased_susceptibility_to | 1.03881304 |
| 67 | MP0001905_abnormal_dopamine_level | 1.00962879 |
| 68 | MP0005166_decreased_susceptibility_to | 1.00890345 |
| 69 | MP0002876_abnormal_thyroid_physiology | 0.99211293 |
| 70 | MP0002736_abnormal_nociception_after | 0.98823582 |
| 71 | MP0009763_increased_sensitivity_to | 0.98632284 |
| 72 | MP0003806_abnormal_nucleotide_metabolis | 0.95329669 |
| 73 | MP0001968_abnormal_touch/_nociception | 0.94288996 |
| 74 | MP0001986_abnormal_taste_sensitivity | 0.92429344 |
| 75 | MP0005253_abnormal_eye_physiology | 0.91571663 |
| 76 | MP0002277_abnormal_respiratory_mucosa | 0.90466718 |
| 77 | MP0003786_premature_aging | 0.90423914 |
| 78 | MP0005075_abnormal_melanosome_morpholog | 0.89219273 |
| 79 | MP0001542_abnormal_bone_strength | 0.86102911 |
| 80 | MP0002638_abnormal_pupillary_reflex | 0.84489915 |
| 81 | MP0001853_heart_inflammation | 0.83950756 |
| 82 | MP0005503_abnormal_tendon_morphology | 0.81992261 |
| 83 | MP0006036_abnormal_mitochondrial_physio | 0.81915521 |
| 84 | MP0005464_abnormal_platelet_physiology | 0.81781434 |
| 85 | MP0001533_abnormal_skeleton_physiology | 0.81158767 |
| 86 | MP0009643_abnormal_urine_homeostasis | 0.80094486 |
| 87 | MP0005636_abnormal_mineral_homeostasis | 0.80067271 |
| 88 | MP0001485_abnormal_pinna_reflex | 0.78938317 |
| 89 | MP0005085_abnormal_gallbladder_physiolo | 0.76059850 |
| 90 | MP0002693_abnormal_pancreas_physiology | 0.73985032 |
| 91 | MP0001664_abnormal_digestion | 0.72496742 |
| 92 | MP0005389_reproductive_system_phenotype | 0.72373367 |
| 93 | MP0004134_abnormal_chest_morphology | 0.70843207 |
| 94 | MP0003646_muscle_fatigue | 0.70149120 |
| 95 | MP0003195_calcinosis | 0.69811929 |
| 96 | MP0006276_abnormal_autonomic_nervous | 0.69756335 |
| 97 | MP0004947_skin_inflammation | 0.68374729 |
| 98 | MP0001501_abnormal_sleep_pattern | 0.68330865 |
| 99 | MP0002019_abnormal_tumor_incidence | 0.67362183 |
| 100 | MP0003075_altered_response_to | 0.67106461 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 5.81914380 |
| 2 | IgG deficiency (HP:0004315) | 4.74849179 |
| 3 | Autoimmune hemolytic anemia (HP:0001890) | 4.70817044 |
| 4 | Hypoproteinemia (HP:0003075) | 4.69828020 |
| 5 | T lymphocytopenia (HP:0005403) | 4.68487934 |
| 6 | Abnormality of T cell number (HP:0011839) | 4.60462862 |
| 7 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.02014706 |
| 8 | 3-Methylglutaconic aciduria (HP:0003535) | 3.95965957 |
| 9 | Congenital stationary night blindness (HP:0007642) | 3.73232520 |
| 10 | Abnormality of B cell number (HP:0010975) | 3.69718273 |
| 11 | Severe combined immunodeficiency (HP:0004430) | 3.69189169 |
| 12 | Mitochondrial inheritance (HP:0001427) | 3.60004849 |
| 13 | Increased IgM level (HP:0003496) | 3.57911083 |
| 14 | Abnormality of the prostate (HP:0008775) | 3.51057139 |
| 15 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.48002208 |
| 16 | Hepatocellular necrosis (HP:0001404) | 3.31900079 |
| 17 | Abnormality of T cells (HP:0002843) | 3.21356001 |
| 18 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.17706176 |
| 19 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.17706176 |
| 20 | Increased intramyocellular lipid droplets (HP:0012240) | 3.11000302 |
| 21 | Autoimmune thrombocytopenia (HP:0001973) | 3.04721618 |
| 22 | Acute necrotizing encephalopathy (HP:0006965) | 3.04533213 |
| 23 | Increased CSF lactate (HP:0002490) | 3.01847284 |
| 24 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.01100426 |
| 25 | Hepatic necrosis (HP:0002605) | 2.97622519 |
| 26 | Congenital, generalized hypertrichosis (HP:0004540) | 2.96180375 |
| 27 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.95302621 |
| 28 | B lymphocytopenia (HP:0010976) | 2.95030784 |
| 29 | Stomatitis (HP:0010280) | 2.91430300 |
| 30 | Increased hepatocellular lipid droplets (HP:0006565) | 2.91087154 |
| 31 | Combined immunodeficiency (HP:0005387) | 2.86453762 |
| 32 | Renal Fanconi syndrome (HP:0001994) | 2.84523599 |
| 33 | Thyroiditis (HP:0100646) | 2.82621521 |
| 34 | Abnormality of eosinophils (HP:0001879) | 2.72762333 |
| 35 | Pancytopenia (HP:0001876) | 2.67868361 |
| 36 | Oral leukoplakia (HP:0002745) | 2.54625337 |
| 37 | Radial bowing (HP:0002986) | 2.53157610 |
| 38 | Recurrent bronchitis (HP:0002837) | 2.52685710 |
| 39 | Lipid accumulation in hepatocytes (HP:0006561) | 2.51519149 |
| 40 | Acute encephalopathy (HP:0006846) | 2.49127005 |
| 41 | Progressive macrocephaly (HP:0004481) | 2.48922672 |
| 42 | Eosinophilia (HP:0001880) | 2.48403407 |
| 43 | Cerebral palsy (HP:0100021) | 2.47906602 |
| 44 | Abnormal albumin level (HP:0012116) | 2.46454895 |
| 45 | Hypoalbuminemia (HP:0003073) | 2.46454895 |
| 46 | Increased muscle lipid content (HP:0009058) | 2.45474705 |
| 47 | Obstructive lung disease (HP:0006536) | 2.43818021 |
| 48 | Chronic obstructive pulmonary disease (HP:0006510) | 2.43818021 |
| 49 | Methylmalonic acidemia (HP:0002912) | 2.42429178 |
| 50 | Azoospermia (HP:0000027) | 2.33247265 |
| 51 | Generalized aminoaciduria (HP:0002909) | 2.33145736 |
| 52 | Meningitis (HP:0001287) | 2.31559393 |
| 53 | Chronic diarrhea (HP:0002028) | 2.28573291 |
| 54 | Hemoptysis (HP:0002105) | 2.26496130 |
| 55 | Vasculitis (HP:0002633) | 2.24806505 |
| 56 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.23688984 |
| 57 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.22101847 |
| 58 | Stomach cancer (HP:0012126) | 2.18623562 |
| 59 | Absent/shortened dynein arms (HP:0200106) | 2.16662183 |
| 60 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.16662183 |
| 61 | Abnormal spermatogenesis (HP:0008669) | 2.13595783 |
| 62 | Lymphopenia (HP:0001888) | 2.13278518 |
| 63 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.12864401 |
| 64 | Recurrent cutaneous fungal infections (HP:0011370) | 2.12864401 |
| 65 | Pancreatic cysts (HP:0001737) | 2.11398147 |
| 66 | Exertional dyspnea (HP:0002875) | 2.09623317 |
| 67 | Abnormality of the pleura (HP:0002103) | 2.09407413 |
| 68 | Attenuation of retinal blood vessels (HP:0007843) | 2.09188754 |
| 69 | Bronchitis (HP:0012387) | 2.07055565 |
| 70 | Constricted visual fields (HP:0001133) | 2.06734021 |
| 71 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.05915184 |
| 72 | Gangrene (HP:0100758) | 2.05397395 |
| 73 | Cerebral edema (HP:0002181) | 2.05239021 |
| 74 | Pulmonary infiltrates (HP:0002113) | 2.02162884 |
| 75 | Prostate neoplasm (HP:0100787) | 2.01107807 |
| 76 | Increased serum lactate (HP:0002151) | 1.99635285 |
| 77 | Acute hepatic failure (HP:0006554) | 1.99131251 |
| 78 | Lactic acidosis (HP:0003128) | 1.97141634 |
| 79 | Encephalitis (HP:0002383) | 1.96168831 |
| 80 | Pustule (HP:0200039) | 1.95504374 |
| 81 | Optic disc pallor (HP:0000543) | 1.95489141 |
| 82 | Lymphoma (HP:0002665) | 1.95122687 |
| 83 | Decreased central vision (HP:0007663) | 1.94823060 |
| 84 | Leukocytosis (HP:0001974) | 1.93476233 |
| 85 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.92334220 |
| 86 | Type I transferrin isoform profile (HP:0003642) | 1.89699891 |
| 87 | Ureteral stenosis (HP:0000071) | 1.89559821 |
| 88 | True hermaphroditism (HP:0010459) | 1.87200278 |
| 89 | Renal cortical cysts (HP:0000803) | 1.87174453 |
| 90 | Abnormality of male internal genitalia (HP:0000022) | 1.86326403 |
| 91 | Abolished electroretinogram (ERG) (HP:0000550) | 1.85241935 |
| 92 | Gastrointestinal infarctions (HP:0005244) | 1.85049482 |
| 93 | Abnormality of renal resorption (HP:0011038) | 1.83548034 |
| 94 | Abnormality of T cell physiology (HP:0011840) | 1.82363153 |
| 95 | Pulmonary fibrosis (HP:0002206) | 1.81548998 |
| 96 | Recurrent fungal infections (HP:0002841) | 1.80439426 |
| 97 | Skin rash (HP:0000988) | 1.79546826 |
| 98 | IgM deficiency (HP:0002850) | 1.79353461 |
| 99 | Severe visual impairment (HP:0001141) | 1.78023577 |
| 100 | Abnormality of macrophages (HP:0004311) | 1.77760289 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 5.16918027 |
| 2 | KDR | 5.10872470 |
| 3 | MAP3K12 | 3.71654167 |
| 4 | TAOK3 | 3.13054565 |
| 5 | TESK2 | 2.90405354 |
| 6 | SCYL2 | 2.89938276 |
| 7 | TLK1 | 2.59044472 |
| 8 | BCKDK | 2.44089305 |
| 9 | ITK | 2.42590760 |
| 10 | MAP4K1 | 2.37122654 |
| 11 | MYLK | 2.27850507 |
| 12 | BMPR2 | 2.10946455 |
| 13 | ADRBK2 | 2.06543339 |
| 14 | ZAK | 1.83988348 |
| 15 | GRK1 | 1.79533622 |
| 16 | CDK19 | 1.68300445 |
| 17 | MAP4K2 | 1.62486417 |
| 18 | BUB1 | 1.61961585 |
| 19 | STK16 | 1.55176289 |
| 20 | MST4 | 1.52082451 |
| 21 | SYK | 1.46200267 |
| 22 | VRK2 | 1.43990875 |
| 23 | BTK | 1.41418054 |
| 24 | EIF2AK3 | 1.41004268 |
| 25 | ERBB3 | 1.40999457 |
| 26 | PINK1 | 1.38980636 |
| 27 | TEC | 1.35316098 |
| 28 | MUSK | 1.33760557 |
| 29 | GRK6 | 1.32018215 |
| 30 | NUAK1 | 1.24520773 |
| 31 | NEK1 | 1.18575034 |
| 32 | TESK1 | 1.18492452 |
| 33 | CSK | 1.16893384 |
| 34 | FES | 1.14558211 |
| 35 | GRK7 | 1.09041503 |
| 36 | LCK | 1.07120336 |
| 37 | PASK | 1.04989619 |
| 38 | ZAP70 | 1.03911966 |
| 39 | CDK8 | 1.02756315 |
| 40 | VRK1 | 1.01232859 |
| 41 | LIMK1 | 1.00515256 |
| 42 | FRK | 0.99955017 |
| 43 | KIT | 0.97314606 |
| 44 | OXSR1 | 0.95021130 |
| 45 | PRKCQ | 0.93358498 |
| 46 | MAPKAPK3 | 0.93129879 |
| 47 | INSRR | 0.92907814 |
| 48 | LYN | 0.89646491 |
| 49 | ILK | 0.88495486 |
| 50 | TRPM7 | 0.88259511 |
| 51 | ROCK1 | 0.87790003 |
| 52 | WNK4 | 0.87342005 |
| 53 | DAPK1 | 0.86195925 |
| 54 | JAK3 | 0.82685364 |
| 55 | IKBKB | 0.80460698 |
| 56 | CSF1R | 0.75202465 |
| 57 | IGF1R | 0.73890885 |
| 58 | OBSCN | 0.72559279 |
| 59 | TIE1 | 0.66768840 |
| 60 | RIPK4 | 0.65706433 |
| 61 | CAMKK2 | 0.62893282 |
| 62 | PIK3CA | 0.60780905 |
| 63 | MAP3K11 | 0.58089116 |
| 64 | HCK | 0.54072540 |
| 65 | WNK3 | 0.50444747 |
| 66 | FYN | 0.50195965 |
| 67 | DAPK3 | 0.46111524 |
| 68 | PRKCA | 0.45033286 |
| 69 | RPS6KA5 | 0.44473185 |
| 70 | PLK2 | 0.44385940 |
| 71 | ABL1 | 0.43042015 |
| 72 | IKBKE | 0.42310571 |
| 73 | LMTK2 | 0.40760671 |
| 74 | ERBB2 | 0.39800698 |
| 75 | PIM1 | 0.39190394 |
| 76 | STK39 | 0.39010752 |
| 77 | CAMK2A | 0.38348995 |
| 78 | ADRBK1 | 0.38123603 |
| 79 | INSR | 0.36135067 |
| 80 | TRIM28 | 0.36000262 |
| 81 | PAK1 | 0.35485119 |
| 82 | BLK | 0.34858499 |
| 83 | CSNK1G3 | 0.33704977 |
| 84 | PRKACA | 0.33508331 |
| 85 | BMPR1B | 0.33320830 |
| 86 | PIK3CG | 0.32643835 |
| 87 | MATK | 0.32340904 |
| 88 | CSNK1A1 | 0.31225991 |
| 89 | PAK4 | 0.31097491 |
| 90 | CSNK2A1 | 0.30878518 |
| 91 | TBK1 | 0.30460030 |
| 92 | PRKCD | 0.29077480 |
| 93 | EGFR | 0.29049173 |
| 94 | PHKG2 | 0.27492310 |
| 95 | PHKG1 | 0.27492310 |
| 96 | MAP2K6 | 0.23547922 |
| 97 | MAPK13 | 0.22049606 |
| 98 | PRKCE | 0.21501298 |
| 99 | PRKCB | 0.21259280 |
| 100 | CAMKK1 | 0.20823511 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.40814421 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.04677117 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.81631408 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.63537340 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 3.63366034 |
| 6 | Asthma_Homo sapiens_hsa05310 | 3.43183065 |
| 7 | Antigen processing and presentation_Homo sapiens_hsa04612 | 3.25582968 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.23544566 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.92747719 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.66736230 |
| 11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.63723276 |
| 12 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.16634375 |
| 13 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.10606121 |
| 14 | Ribosome_Homo sapiens_hsa03010 | 1.96882360 |
| 15 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.89873273 |
| 16 | Alzheimers disease_Homo sapiens_hsa05010 | 1.87047612 |
| 17 | Viral myocarditis_Homo sapiens_hsa05416 | 1.86236619 |
| 18 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.85238528 |
| 19 | Protein export_Homo sapiens_hsa03060 | 1.78520600 |
| 20 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.70252435 |
| 21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.64774004 |
| 22 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.61457618 |
| 23 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.53922543 |
| 24 | Huntingtons disease_Homo sapiens_hsa05016 | 1.51688583 |
| 25 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.49702967 |
| 26 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.44047086 |
| 27 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.42738099 |
| 28 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.42143195 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.24247450 |
| 30 | RNA polymerase_Homo sapiens_hsa03020 | 1.10676850 |
| 31 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.10337226 |
| 32 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.00228832 |
| 33 | Leishmaniasis_Homo sapiens_hsa05140 | 0.98287150 |
| 34 | Malaria_Homo sapiens_hsa05144 | 0.97753470 |
| 35 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.87436177 |
| 36 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.87391057 |
| 37 | Salmonella infection_Homo sapiens_hsa05132 | 0.85609445 |
| 38 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.85597017 |
| 39 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.84539896 |
| 40 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.78858997 |
| 41 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.75726881 |
| 42 | Measles_Homo sapiens_hsa05162 | 0.74917789 |
| 43 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.73708383 |
| 44 | Shigellosis_Homo sapiens_hsa05131 | 0.73236552 |
| 45 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.67476450 |
| 46 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.66344413 |
| 47 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.62624492 |
| 48 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.60762090 |
| 49 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.59754711 |
| 50 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.59169740 |
| 51 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.58880896 |
| 52 | Retinol metabolism_Homo sapiens_hsa00830 | 0.53815623 |
| 53 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.52771402 |
| 54 | Peroxisome_Homo sapiens_hsa04146 | 0.52676015 |
| 55 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.52615331 |
| 56 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.51993625 |
| 57 | Olfactory transduction_Homo sapiens_hsa04740 | 0.49258177 |
| 58 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.48682945 |
| 59 | RNA degradation_Homo sapiens_hsa03018 | 0.46433433 |
| 60 | Phagosome_Homo sapiens_hsa04145 | 0.44250168 |
| 61 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.43548212 |
| 62 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.41599500 |
| 63 | Homologous recombination_Homo sapiens_hsa03440 | 0.41289056 |
| 64 | Tuberculosis_Homo sapiens_hsa05152 | 0.40684679 |
| 65 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.40296758 |
| 66 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.38907224 |
| 67 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.36741156 |
| 68 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.36397731 |
| 69 | Purine metabolism_Homo sapiens_hsa00230 | 0.35619281 |
| 70 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.34160551 |
| 71 | Taste transduction_Homo sapiens_hsa04742 | 0.32388222 |
| 72 | Legionellosis_Homo sapiens_hsa05134 | 0.32343267 |
| 73 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.31712290 |
| 74 | Influenza A_Homo sapiens_hsa05164 | 0.31051452 |
| 75 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.30146815 |
| 76 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.27111320 |
| 77 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.26466772 |
| 78 | HTLV-I infection_Homo sapiens_hsa05166 | 0.26010018 |
| 79 | Pertussis_Homo sapiens_hsa05133 | 0.25929261 |
| 80 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.25131044 |
| 81 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.24246253 |
| 82 | Metabolic pathways_Homo sapiens_hsa01100 | 0.23669123 |
| 83 | ABC transporters_Homo sapiens_hsa02010 | 0.22427812 |
| 84 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.21055105 |
| 85 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.20669320 |
| 86 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.20231484 |
| 87 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.19518673 |
| 88 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.18204090 |
| 89 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.16657332 |
| 90 | Basal transcription factors_Homo sapiens_hsa03022 | 0.16335240 |
| 91 | Nicotine addiction_Homo sapiens_hsa05033 | 0.16121939 |
| 92 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.16119874 |
| 93 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.15028726 |
| 94 | Morphine addiction_Homo sapiens_hsa05032 | 0.13999214 |
| 95 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.13324380 |
| 96 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.13023163 |
| 97 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.12605028 |
| 98 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.11272310 |
| 99 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.10914976 |
| 100 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.10579216 |

