

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 6.02293019 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.98171354 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.86337957 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 4.86337957 |
| 5 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.42580149 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.29312658 |
| 7 | DNA deamination (GO:0045006) | 4.14730256 |
| 8 | GTP biosynthetic process (GO:0006183) | 4.08985281 |
| 9 | cytidine metabolic process (GO:0046087) | 3.87794491 |
| 10 | cytidine catabolic process (GO:0006216) | 3.87794491 |
| 11 | cytidine deamination (GO:0009972) | 3.87794491 |
| 12 | GPI anchor metabolic process (GO:0006505) | 3.75852736 |
| 13 | histamine transport (GO:0051608) | 3.63888890 |
| 14 | terpenoid biosynthetic process (GO:0016114) | 3.61739180 |
| 15 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.58274543 |
| 16 | positive regulation of prostaglandin secretion (GO:0032308) | 3.49034664 |
| 17 | neurotransmitter catabolic process (GO:0042135) | 3.44930672 |
| 18 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.42790158 |
| 19 | sequestering of actin monomers (GO:0042989) | 3.39699426 |
| 20 | GPI anchor biosynthetic process (GO:0006506) | 3.39611217 |
| 21 | regulation of prostaglandin secretion (GO:0032306) | 3.39569415 |
| 22 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.38332510 |
| 23 | protein complex biogenesis (GO:0070271) | 3.37854710 |
| 24 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.36969501 |
| 25 | regulation of mesoderm development (GO:2000380) | 3.35946848 |
| 26 | T cell apoptotic process (GO:0070231) | 3.35135207 |
| 27 | UTP biosynthetic process (GO:0006228) | 3.27106465 |
| 28 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.26982508 |
| 29 | chaperone-mediated protein transport (GO:0072321) | 3.25064653 |
| 30 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.22254206 |
| 31 | electron transport chain (GO:0022900) | 3.21206312 |
| 32 | protein neddylation (GO:0045116) | 3.20320210 |
| 33 | positive regulation of amino acid transport (GO:0051957) | 3.19782652 |
| 34 | behavioral response to nicotine (GO:0035095) | 3.19718744 |
| 35 | negative regulation of telomere maintenance (GO:0032205) | 3.18386916 |
| 36 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.18220120 |
| 37 | respiratory electron transport chain (GO:0022904) | 3.18037993 |
| 38 | peptidyl-histidine modification (GO:0018202) | 3.17494518 |
| 39 | mannosylation (GO:0097502) | 3.17228234 |
| 40 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.15549541 |
| 41 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.07696068 |
| 42 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.07696068 |
| 43 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.07326245 |
| 44 | cullin deneddylation (GO:0010388) | 3.06176504 |
| 45 | mitochondrial DNA replication (GO:0006264) | 3.05869277 |
| 46 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.05434199 |
| 47 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.05434199 |
| 48 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.05434199 |
| 49 | rRNA modification (GO:0000154) | 3.03959173 |
| 50 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.03509736 |
| 51 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.03221533 |
| 52 | lymphocyte apoptotic process (GO:0070227) | 3.03031768 |
| 53 | hydrogen ion transmembrane transport (GO:1902600) | 3.00769365 |
| 54 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.00339427 |
| 55 | UTP metabolic process (GO:0046051) | 2.99847241 |
| 56 | negative regulation by host of viral transcription (GO:0043922) | 2.97273040 |
| 57 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.96526793 |
| 58 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.95482692 |
| 59 | NADH dehydrogenase complex assembly (GO:0010257) | 2.95482692 |
| 60 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.95482692 |
| 61 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.95020623 |
| 62 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.95020623 |
| 63 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.93840055 |
| 64 | proton transport (GO:0015992) | 2.93806350 |
| 65 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.93685972 |
| 66 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.92861567 |
| 67 | hydrogen transport (GO:0006818) | 2.89496960 |
| 68 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.89284566 |
| 69 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.89284566 |
| 70 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.89021251 |
| 71 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.85347370 |
| 72 | protein deneddylation (GO:0000338) | 2.85095713 |
| 73 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.83987776 |
| 74 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.83241379 |
| 75 | response to pheromone (GO:0019236) | 2.83068340 |
| 76 | platelet dense granule organization (GO:0060155) | 2.81062877 |
| 77 | DNA strand renaturation (GO:0000733) | 2.79372570 |
| 78 | organelle membrane fusion (GO:0090174) | 2.78239115 |
| 79 | CTP metabolic process (GO:0046036) | 2.76506213 |
| 80 | CTP biosynthetic process (GO:0006241) | 2.76506213 |
| 81 | negative regulation of ligase activity (GO:0051352) | 2.75904360 |
| 82 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.75904360 |
| 83 | gonadal mesoderm development (GO:0007506) | 2.74159074 |
| 84 | fucose catabolic process (GO:0019317) | 2.72283810 |
| 85 | L-fucose metabolic process (GO:0042354) | 2.72283810 |
| 86 | L-fucose catabolic process (GO:0042355) | 2.72283810 |
| 87 | termination of RNA polymerase III transcription (GO:0006386) | 2.72241830 |
| 88 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.72241830 |
| 89 | histamine secretion (GO:0001821) | 2.71708492 |
| 90 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.68791713 |
| 91 | ER overload response (GO:0006983) | 2.67748596 |
| 92 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.66689624 |
| 93 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.62582220 |
| 94 | positive regulation of organic acid transport (GO:0032892) | 2.61519377 |
| 95 | ATP biosynthetic process (GO:0006754) | 2.61013587 |
| 96 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.60880669 |
| 97 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.60411686 |
| 98 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.60231490 |
| 99 | protein peptidyl-prolyl isomerization (GO:0000413) | 2.58409142 |
| 100 | artery smooth muscle contraction (GO:0014824) | 2.57863750 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 6.23791627 |
| 2 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.02051467 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.66307202 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.48695136 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.42603866 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.15563692 |
| 7 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.98448079 |
| 8 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.66022300 |
| 9 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.64987072 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.49132878 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.45390171 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.44017089 |
| 13 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.26998142 |
| 14 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.13197042 |
| 15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.07588258 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.04041596 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.91401530 |
| 18 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.88655286 |
| 19 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.88428769 |
| 20 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.84885388 |
| 21 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.71682769 |
| 22 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.70246163 |
| 23 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.64676527 |
| 24 | EWS_26573619_Chip-Seq_HEK293_Human | 1.62500086 |
| 25 | AR_20517297_ChIP-Seq_VCAP_Human | 1.59985212 |
| 26 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.59321633 |
| 27 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.58241101 |
| 28 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.55871183 |
| 29 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.51017121 |
| 30 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.50040478 |
| 31 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.49907107 |
| 32 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.49279695 |
| 33 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.47889376 |
| 34 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.47089611 |
| 35 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.47089611 |
| 36 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.46015476 |
| 37 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.44631992 |
| 38 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.41640468 |
| 39 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.40417873 |
| 40 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.38103336 |
| 41 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.37079582 |
| 42 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.36446908 |
| 43 | P300_19829295_ChIP-Seq_ESCs_Human | 1.35675485 |
| 44 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.34442610 |
| 45 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.34261257 |
| 46 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.31394749 |
| 47 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.27249869 |
| 48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.26354542 |
| 49 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.25675671 |
| 50 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.25238291 |
| 51 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.24294669 |
| 52 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.24294669 |
| 53 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.23432551 |
| 54 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.22475615 |
| 55 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.20538618 |
| 56 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.20365651 |
| 57 | FUS_26573619_Chip-Seq_HEK293_Human | 1.19521271 |
| 58 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.18059300 |
| 59 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.18056263 |
| 60 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.17758729 |
| 61 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.17177902 |
| 62 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.16764459 |
| 63 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.15943223 |
| 64 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.13169505 |
| 65 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.12713154 |
| 66 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.11340154 |
| 67 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.10656541 |
| 68 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.09812240 |
| 69 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.07378826 |
| 70 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.06529980 |
| 71 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04920379 |
| 72 | GATA3_26560356_Chip-Seq_TH2_Human | 1.02370941 |
| 73 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.01500031 |
| 74 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.00600122 |
| 75 | NCOR_22424771_ChIP-Seq_293T_Human | 1.00429454 |
| 76 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.99909401 |
| 77 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.98904145 |
| 78 | ERA_21632823_ChIP-Seq_H3396_Human | 0.98811698 |
| 79 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.98625277 |
| 80 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.97270414 |
| 81 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.94503188 |
| 82 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.93198586 |
| 83 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.92423474 |
| 84 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.91744895 |
| 85 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.91700601 |
| 86 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.91252450 |
| 87 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.90455012 |
| 88 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.89575757 |
| 89 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.89344613 |
| 90 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.89323647 |
| 91 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.87379429 |
| 92 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.87283547 |
| 93 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.85873052 |
| 94 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.85831237 |
| 95 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.85721066 |
| 96 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.85426596 |
| 97 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.84638948 |
| 98 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.84368523 |
| 99 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.82296497 |
| 100 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.80796602 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004147_increased_porphyrin_level | 4.04089551 |
| 2 | MP0010386_abnormal_urinary_bladder | 3.22675149 |
| 3 | MP0000372_irregular_coat_pigmentation | 3.21629453 |
| 4 | MP0005671_abnormal_response_to | 2.88470101 |
| 5 | MP0001835_abnormal_antigen_presentation | 2.87755094 |
| 6 | MP0002138_abnormal_hepatobiliary_system | 2.80498543 |
| 7 | MP0002163_abnormal_gland_morphology | 2.77007358 |
| 8 | MP0008875_abnormal_xenobiotic_pharmacok | 2.45626489 |
| 9 | MP0008872_abnormal_physiological_respon | 2.45087581 |
| 10 | MP0006035_abnormal_mitochondrial_morpho | 2.42123951 |
| 11 | MP0002234_abnormal_pharynx_morphology | 2.38327983 |
| 12 | MP0005075_abnormal_melanosome_morpholog | 2.34092800 |
| 13 | MP0002837_dystrophic_cardiac_calcinosis | 2.29977062 |
| 14 | MP0006036_abnormal_mitochondrial_physio | 2.25786795 |
| 15 | MP0001873_stomach_inflammation | 2.19911424 |
| 16 | MP0002736_abnormal_nociception_after | 2.17921551 |
| 17 | MP0002735_abnormal_chemical_nociception | 2.15927266 |
| 18 | MP0001968_abnormal_touch/_nociception | 2.09654609 |
| 19 | MP0006072_abnormal_retinal_apoptosis | 2.07037285 |
| 20 | MP0005084_abnormal_gallbladder_morpholo | 2.03350079 |
| 21 | MP0002102_abnormal_ear_morphology | 1.90760035 |
| 22 | MP0005408_hypopigmentation | 1.83335112 |
| 23 | MP0003195_calcinosis | 1.81207256 |
| 24 | MP0004145_abnormal_muscle_electrophysio | 1.77711495 |
| 25 | MP0005167_abnormal_blood-brain_barrier | 1.70678006 |
| 26 | MP0006082_CNS_inflammation | 1.68014564 |
| 27 | MP0003283_abnormal_digestive_organ | 1.62467827 |
| 28 | MP0004742_abnormal_vestibular_system | 1.58832590 |
| 29 | MP0003786_premature_aging | 1.56072877 |
| 30 | MP0004885_abnormal_endolymph | 1.50852442 |
| 31 | MP0001970_abnormal_pain_threshold | 1.46546746 |
| 32 | MP0002272_abnormal_nervous_system | 1.44805788 |
| 33 | MP0005379_endocrine/exocrine_gland_phen | 1.43869563 |
| 34 | MP0005551_abnormal_eye_electrophysiolog | 1.43445119 |
| 35 | MP0003878_abnormal_ear_physiology | 1.43377539 |
| 36 | MP0005377_hearing/vestibular/ear_phenot | 1.43377539 |
| 37 | MP0008775_abnormal_heart_ventricle | 1.42016368 |
| 38 | MP0005387_immune_system_phenotype | 1.40537281 |
| 39 | MP0001790_abnormal_immune_system | 1.40537281 |
| 40 | MP0002148_abnormal_hypersensitivity_rea | 1.39641802 |
| 41 | MP0002638_abnormal_pupillary_reflex | 1.38910023 |
| 42 | MP0003866_abnormal_defecation | 1.37287373 |
| 43 | MP0000685_abnormal_immune_system | 1.35965414 |
| 44 | MP0002938_white_spotting | 1.35661399 |
| 45 | MP0001800_abnormal_humoral_immune | 1.33142577 |
| 46 | MP0003763_abnormal_thymus_physiology | 1.30999116 |
| 47 | MP0006276_abnormal_autonomic_nervous | 1.24721963 |
| 48 | MP0009785_altered_susceptibility_to | 1.21304261 |
| 49 | MP0003950_abnormal_plasma_membrane | 1.20157513 |
| 50 | MP0003806_abnormal_nucleotide_metabolis | 1.19425048 |
| 51 | MP0004043_abnormal_pH_regulation | 1.19261350 |
| 52 | MP0001756_abnormal_urination | 1.18245311 |
| 53 | MP0004142_abnormal_muscle_tone | 1.16271850 |
| 54 | MP0003119_abnormal_digestive_system | 1.14963555 |
| 55 | MP0001986_abnormal_taste_sensitivity | 1.13850861 |
| 56 | MP0005085_abnormal_gallbladder_physiolo | 1.13793738 |
| 57 | MP0009745_abnormal_behavioral_response | 1.13207107 |
| 58 | MP0002452_abnormal_antigen_presenting | 1.13133035 |
| 59 | MP0001348_abnormal_lacrimal_gland | 1.12823074 |
| 60 | MP0004084_abnormal_cardiac_muscle | 1.09851627 |
| 61 | MP0009333_abnormal_splenocyte_physiolog | 1.08079671 |
| 62 | MP0002277_abnormal_respiratory_mucosa | 1.05408895 |
| 63 | MP0002733_abnormal_thermal_nociception | 1.02969917 |
| 64 | MP0005253_abnormal_eye_physiology | 1.00694330 |
| 65 | MP0002693_abnormal_pancreas_physiology | 0.98098159 |
| 66 | MP0002723_abnormal_immune_serum | 0.96438404 |
| 67 | MP0003011_delayed_dark_adaptation | 0.96081187 |
| 68 | MP0005365_abnormal_bile_salt | 0.94455037 |
| 69 | MP0005389_reproductive_system_phenotype | 0.92571306 |
| 70 | MP0001663_abnormal_digestive_system | 0.90533452 |
| 71 | MP0001819_abnormal_immune_cell | 0.89046844 |
| 72 | MP0001879_abnormal_lymphatic_vessel | 0.87491347 |
| 73 | MP0009643_abnormal_urine_homeostasis | 0.85449633 |
| 74 | MP0005670_abnormal_white_adipose | 0.85339033 |
| 75 | MP0004215_abnormal_myocardial_fiber | 0.85135529 |
| 76 | MP0005645_abnormal_hypothalamus_physiol | 0.82879610 |
| 77 | MP0000538_abnormal_urinary_bladder | 0.82582213 |
| 78 | MP0005646_abnormal_pituitary_gland | 0.82229777 |
| 79 | MP0009697_abnormal_copulation | 0.81307775 |
| 80 | MP0005000_abnormal_immune_tolerance | 0.80923230 |
| 81 | MP0003186_abnormal_redox_activity | 0.80599144 |
| 82 | MP0002734_abnormal_mechanical_nocicepti | 0.80422741 |
| 83 | MP0005360_urolithiasis | 0.77968261 |
| 84 | MP0002420_abnormal_adaptive_immunity | 0.76924754 |
| 85 | MP0001293_anophthalmia | 0.76717727 |
| 86 | MP0005410_abnormal_fertilization | 0.76599989 |
| 87 | MP0000230_abnormal_systemic_arterial | 0.74613758 |
| 88 | MP0001919_abnormal_reproductive_system | 0.73683003 |
| 89 | MP0000015_abnormal_ear_pigmentation | 0.73275515 |
| 90 | MP0002160_abnormal_reproductive_system | 0.72908305 |
| 91 | MP0005636_abnormal_mineral_homeostasis | 0.72583846 |
| 92 | MP0009046_muscle_twitch | 0.72214401 |
| 93 | MP0003136_yellow_coat_color | 0.71966242 |
| 94 | MP0000358_abnormal_cell_content/ | 0.70188131 |
| 95 | MP0008873_increased_physiological_sensi | 0.68831997 |
| 96 | MP0002064_seizures | 0.65359868 |
| 97 | MP0003252_abnormal_bile_duct | 0.65282223 |
| 98 | MP0008058_abnormal_DNA_repair | 0.64378378 |
| 99 | MP0004381_abnormal_hair_follicle | 0.64346883 |
| 100 | MP0002557_abnormal_social/conspecific_i | 0.63640351 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | 3-Methylglutaconic aciduria (HP:0003535) | 5.04437008 |
| 2 | Absent/shortened dynein arms (HP:0200106) | 4.50615238 |
| 3 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 4.50615238 |
| 4 | IgG deficiency (HP:0004315) | 3.87059054 |
| 5 | Congenital stationary night blindness (HP:0007642) | 3.64501691 |
| 6 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.43023381 |
| 7 | Ulnar claw (HP:0001178) | 3.35060630 |
| 8 | Colon cancer (HP:0003003) | 3.25942147 |
| 9 | Hypoproteinemia (HP:0003075) | 3.20944369 |
| 10 | Cerebral palsy (HP:0100021) | 3.08107034 |
| 11 | Stomatitis (HP:0010280) | 3.05887509 |
| 12 | Acute necrotizing encephalopathy (HP:0006965) | 2.98635038 |
| 13 | Abolished electroretinogram (ERG) (HP:0000550) | 2.98498083 |
| 14 | Mitochondrial inheritance (HP:0001427) | 2.94490144 |
| 15 | Abnormality of B cell number (HP:0010975) | 2.90283495 |
| 16 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.89708014 |
| 17 | B lymphocytopenia (HP:0010976) | 2.83295141 |
| 18 | Increased IgM level (HP:0003496) | 2.75936009 |
| 19 | Acute encephalopathy (HP:0006846) | 2.75558272 |
| 20 | Increased CSF lactate (HP:0002490) | 2.74028869 |
| 21 | Constricted visual fields (HP:0001133) | 2.72934478 |
| 22 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.68616210 |
| 23 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.68616210 |
| 24 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.65689986 |
| 25 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.65689986 |
| 26 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.63088498 |
| 27 | Hypoplasia of the fovea (HP:0007750) | 2.63088498 |
| 28 | Parakeratosis (HP:0001036) | 2.61767098 |
| 29 | Hemoptysis (HP:0002105) | 2.57483746 |
| 30 | Joint swelling (HP:0001386) | 2.53787603 |
| 31 | Increased serum lactate (HP:0002151) | 2.52387775 |
| 32 | Large for gestational age (HP:0001520) | 2.52056988 |
| 33 | Hepatocellular necrosis (HP:0001404) | 2.47578847 |
| 34 | Pancreatic cysts (HP:0001737) | 2.47554899 |
| 35 | Abnormal ciliary motility (HP:0012262) | 2.46764877 |
| 36 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.45952672 |
| 37 | Arthropathy (HP:0003040) | 2.41197881 |
| 38 | Increased hepatocellular lipid droplets (HP:0006565) | 2.36514839 |
| 39 | Renal Fanconi syndrome (HP:0001994) | 2.35678538 |
| 40 | Progressive macrocephaly (HP:0004481) | 2.32158949 |
| 41 | Abnormality of the fovea (HP:0000493) | 2.31205792 |
| 42 | Adactyly (HP:0009776) | 2.30515952 |
| 43 | Abnormal pupillary function (HP:0007686) | 2.29666333 |
| 44 | Abnormality of midbrain morphology (HP:0002418) | 2.28812586 |
| 45 | Molar tooth sign on MRI (HP:0002419) | 2.28812586 |
| 46 | Bilateral microphthalmos (HP:0007633) | 2.27658696 |
| 47 | Abnormality of T cell physiology (HP:0011840) | 2.26473294 |
| 48 | Optic disc pallor (HP:0000543) | 2.25883046 |
| 49 | Lipid accumulation in hepatocytes (HP:0006561) | 2.23684842 |
| 50 | Dyschromatopsia (HP:0007641) | 2.20446035 |
| 51 | Central scotoma (HP:0000603) | 2.18184806 |
| 52 | Abnormality of T cells (HP:0002843) | 2.18180326 |
| 53 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.17474698 |
| 54 | True hermaphroditism (HP:0010459) | 2.15867183 |
| 55 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.13674236 |
| 56 | Lactic acidosis (HP:0003128) | 2.13541471 |
| 57 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.13202966 |
| 58 | Increased intramyocellular lipid droplets (HP:0012240) | 2.11818471 |
| 59 | Fibular aplasia (HP:0002990) | 2.11234048 |
| 60 | Hyperalaninemia (HP:0003348) | 2.11038186 |
| 61 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.11038186 |
| 62 | Abnormality of alanine metabolism (HP:0010916) | 2.11038186 |
| 63 | CNS hypomyelination (HP:0003429) | 2.08314070 |
| 64 | Abnormality of the pleura (HP:0002103) | 2.07921405 |
| 65 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.07793604 |
| 66 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.06295018 |
| 67 | Recurrent cutaneous fungal infections (HP:0011370) | 2.06295018 |
| 68 | Hepatic necrosis (HP:0002605) | 2.05475224 |
| 69 | Pigmentary retinal degeneration (HP:0001146) | 2.04161554 |
| 70 | Abnormality of the prostate (HP:0008775) | 2.03755255 |
| 71 | Pancreatic fibrosis (HP:0100732) | 2.01375777 |
| 72 | Severe visual impairment (HP:0001141) | 1.99712145 |
| 73 | Obstructive lung disease (HP:0006536) | 1.98381305 |
| 74 | Chronic obstructive pulmonary disease (HP:0006510) | 1.98381305 |
| 75 | Attenuation of retinal blood vessels (HP:0007843) | 1.97613780 |
| 76 | Cerebral edema (HP:0002181) | 1.93527205 |
| 77 | Eosinophilia (HP:0001880) | 1.93133277 |
| 78 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.91175601 |
| 79 | Abnormality of the pons (HP:0007361) | 1.89471360 |
| 80 | Tetraparesis (HP:0002273) | 1.88967583 |
| 81 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.88638463 |
| 82 | Vasculitis (HP:0002633) | 1.87828942 |
| 83 | Exertional dyspnea (HP:0002875) | 1.87126721 |
| 84 | Hypoplasia of the thymus (HP:0000778) | 1.85960421 |
| 85 | Progressive microcephaly (HP:0000253) | 1.85870498 |
| 86 | Severe combined immunodeficiency (HP:0004430) | 1.83315724 |
| 87 | Panhypogammaglobulinemia (HP:0003139) | 1.82165412 |
| 88 | Abnormality of eosinophils (HP:0001879) | 1.82008099 |
| 89 | Short 1st metacarpal (HP:0010034) | 1.80361338 |
| 90 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.80361338 |
| 91 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.78938893 |
| 92 | Recurrent sinusitis (HP:0011108) | 1.78806822 |
| 93 | Thyroiditis (HP:0100646) | 1.75941542 |
| 94 | Abnormality of proline metabolism (HP:0010907) | 1.75581227 |
| 95 | Hydroxyprolinuria (HP:0003080) | 1.75581227 |
| 96 | Palpitations (HP:0001962) | 1.75511066 |
| 97 | Increased muscle lipid content (HP:0009058) | 1.74851665 |
| 98 | Unilateral renal agenesis (HP:0000122) | 1.73036398 |
| 99 | Ureteral stenosis (HP:0000071) | 1.72443867 |
| 100 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.71896595 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 4.93373113 |
| 2 | VRK2 | 4.47845395 |
| 3 | TAOK3 | 4.05070523 |
| 4 | MAP3K12 | 3.71078159 |
| 5 | TLK1 | 3.22401240 |
| 6 | STK16 | 3.21087650 |
| 7 | NUAK1 | 2.76568897 |
| 8 | BMPR1B | 2.75924331 |
| 9 | TXK | 2.49985631 |
| 10 | TAF1 | 2.29677602 |
| 11 | TIE1 | 2.16211886 |
| 12 | GRK1 | 2.09496902 |
| 13 | VRK1 | 2.04628518 |
| 14 | MST4 | 2.04589223 |
| 15 | ADRBK2 | 1.92146062 |
| 16 | CSNK1G3 | 1.80683446 |
| 17 | CSNK1A1L | 1.78299835 |
| 18 | MYLK | 1.63442448 |
| 19 | CSNK1G1 | 1.60240393 |
| 20 | PIK3CA | 1.51682038 |
| 21 | CSNK1G2 | 1.45084555 |
| 22 | ACVR1B | 1.44597308 |
| 23 | DYRK2 | 1.42831504 |
| 24 | STK38L | 1.35047744 |
| 25 | PDK2 | 1.31746469 |
| 26 | MAP2K6 | 1.24101939 |
| 27 | CDK8 | 1.23903112 |
| 28 | KDR | 1.22980025 |
| 29 | EPHA3 | 1.20393535 |
| 30 | GRK5 | 1.20076704 |
| 31 | BCKDK | 1.13866229 |
| 32 | WNK3 | 1.09485070 |
| 33 | DAPK1 | 1.09359572 |
| 34 | BUB1 | 1.04949220 |
| 35 | ITK | 1.03179747 |
| 36 | NLK | 0.99846746 |
| 37 | EIF2AK1 | 0.93744109 |
| 38 | EIF2AK3 | 0.93119289 |
| 39 | MAP4K1 | 0.90082390 |
| 40 | ILK | 0.88785611 |
| 41 | WNK4 | 0.87023526 |
| 42 | TGFBR1 | 0.85972010 |
| 43 | MATK | 0.83376455 |
| 44 | PRKCQ | 0.82744409 |
| 45 | LMTK2 | 0.82691564 |
| 46 | ZAK | 0.81947609 |
| 47 | SRPK1 | 0.76448595 |
| 48 | LIMK1 | 0.76256125 |
| 49 | SMG1 | 0.75733589 |
| 50 | PINK1 | 0.75229970 |
| 51 | DAPK2 | 0.75052589 |
| 52 | ARAF | 0.73370811 |
| 53 | MAPKAPK5 | 0.72643318 |
| 54 | TESK2 | 0.70511143 |
| 55 | IKBKB | 0.70489216 |
| 56 | MAP3K9 | 0.67472730 |
| 57 | NME1 | 0.67362748 |
| 58 | MAP3K11 | 0.66524598 |
| 59 | ERBB2 | 0.65343740 |
| 60 | PTK2B | 0.61271460 |
| 61 | RIPK4 | 0.57166855 |
| 62 | DAPK3 | 0.56507311 |
| 63 | FES | 0.54295474 |
| 64 | ADRBK1 | 0.52409398 |
| 65 | FER | 0.49954734 |
| 66 | PRKCE | 0.49768637 |
| 67 | NTRK1 | 0.49080555 |
| 68 | PLK3 | 0.49028801 |
| 69 | CSNK1A1 | 0.47195184 |
| 70 | INSRR | 0.47074998 |
| 71 | FRK | 0.45712644 |
| 72 | CSK | 0.45522676 |
| 73 | TEC | 0.43508515 |
| 74 | TSSK6 | 0.43044303 |
| 75 | EIF2AK2 | 0.40612672 |
| 76 | PRKCG | 0.39125018 |
| 77 | NEK1 | 0.38332894 |
| 78 | TRIM28 | 0.38126568 |
| 79 | PHKG2 | 0.36288048 |
| 80 | PHKG1 | 0.36288048 |
| 81 | SYK | 0.35152433 |
| 82 | OXSR1 | 0.34937631 |
| 83 | CAMK2A | 0.34015900 |
| 84 | PBK | 0.33840363 |
| 85 | EPHB1 | 0.31965515 |
| 86 | MAPK13 | 0.30850508 |
| 87 | PRKCI | 0.30497318 |
| 88 | MAP3K4 | 0.30455774 |
| 89 | CCNB1 | 0.29038136 |
| 90 | TNK2 | 0.27526608 |
| 91 | GSK3A | 0.26738150 |
| 92 | PRKCA | 0.26384881 |
| 93 | CDK19 | 0.25448066 |
| 94 | TYRO3 | 0.24203268 |
| 95 | MINK1 | 0.22830208 |
| 96 | PLK4 | 0.22544454 |
| 97 | STK24 | 0.22529678 |
| 98 | GRK7 | 0.21727676 |
| 99 | MAP2K7 | 0.21520843 |
| 100 | AURKA | 0.20940887 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.12053966 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.56541704 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.42802634 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.33631702 |
| 5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.23281080 |
| 6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.21236131 |
| 7 | Protein export_Homo sapiens_hsa03060 | 3.18241027 |
| 8 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.94666819 |
| 9 | Parkinsons disease_Homo sapiens_hsa05012 | 2.59250195 |
| 10 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.38547501 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.37549997 |
| 12 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.05232548 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 1.97631290 |
| 14 | RNA polymerase_Homo sapiens_hsa03020 | 1.97565826 |
| 15 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.93680573 |
| 16 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.91083982 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 1.78043415 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.64073466 |
| 19 | Phototransduction_Homo sapiens_hsa04744 | 1.63425589 |
| 20 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.50690629 |
| 21 | Ribosome_Homo sapiens_hsa03010 | 1.44677647 |
| 22 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.42698926 |
| 23 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.39107312 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.37093172 |
| 25 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.35173395 |
| 26 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.24133947 |
| 27 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.23737805 |
| 28 | Viral myocarditis_Homo sapiens_hsa05416 | 1.16913914 |
| 29 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.14776919 |
| 30 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.12687932 |
| 31 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.09369927 |
| 32 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.03436543 |
| 33 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.02712448 |
| 34 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.02598028 |
| 35 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.99435746 |
| 36 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.97965901 |
| 37 | Homologous recombination_Homo sapiens_hsa03440 | 0.97779130 |
| 38 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.96689112 |
| 39 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.96260955 |
| 40 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.95528575 |
| 41 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.90984702 |
| 42 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.90143778 |
| 43 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.87034962 |
| 44 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.85256712 |
| 45 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.81290943 |
| 46 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.81193355 |
| 47 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.79908119 |
| 48 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.78795097 |
| 49 | Peroxisome_Homo sapiens_hsa04146 | 0.78714424 |
| 50 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.77149256 |
| 51 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.77064891 |
| 52 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.76374416 |
| 53 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.75804348 |
| 54 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.74975293 |
| 55 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.74851868 |
| 56 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.73805872 |
| 57 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.72303120 |
| 58 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.71269104 |
| 59 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.70339733 |
| 60 | RNA degradation_Homo sapiens_hsa03018 | 0.68249653 |
| 61 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.64104194 |
| 62 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.63124487 |
| 63 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.61684812 |
| 64 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.60026467 |
| 65 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.58399696 |
| 66 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.58353227 |
| 67 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.58291830 |
| 68 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.55229811 |
| 69 | Mismatch repair_Homo sapiens_hsa03430 | 0.54972268 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54368565 |
| 71 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.54307297 |
| 72 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.54123035 |
| 73 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.53789003 |
| 74 | Retinol metabolism_Homo sapiens_hsa00830 | 0.52501640 |
| 75 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.50991057 |
| 76 | Olfactory transduction_Homo sapiens_hsa04740 | 0.50284195 |
| 77 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.48045429 |
| 78 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.47654682 |
| 79 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.46076357 |
| 80 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.43631546 |
| 81 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.42614038 |
| 82 | Purine metabolism_Homo sapiens_hsa00230 | 0.42216767 |
| 83 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.41131440 |
| 84 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.39195348 |
| 85 | GABAergic synapse_Homo sapiens_hsa04727 | 0.37951596 |
| 86 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.37053375 |
| 87 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.35793517 |
| 88 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.35447011 |
| 89 | Sulfur relay system_Homo sapiens_hsa04122 | 0.34140480 |
| 90 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.33964761 |
| 91 | Morphine addiction_Homo sapiens_hsa05032 | 0.33946916 |
| 92 | Taste transduction_Homo sapiens_hsa04742 | 0.33262716 |
| 93 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.30036994 |
| 94 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.29947146 |
| 95 | Nicotine addiction_Homo sapiens_hsa05033 | 0.28302770 |
| 96 | Spliceosome_Homo sapiens_hsa03040 | 0.27057321 |
| 97 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.26499130 |
| 98 | RNA transport_Homo sapiens_hsa03013 | 0.25524840 |
| 99 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.25468618 |
| 100 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.25367944 |

