MYO1B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1hemidesmosome assembly (GO:0031581)7.23588484
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)6.73221428
3L-phenylalanine catabolic process (GO:0006559)6.73221428
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)6.39576006
5L-phenylalanine metabolic process (GO:0006558)6.39576006
6aromatic amino acid family catabolic process (GO:0009074)6.23107036
7indole-containing compound catabolic process (GO:0042436)5.80970583
8indolalkylamine catabolic process (GO:0046218)5.80970583
9tryptophan catabolic process (GO:0006569)5.80970583
10kynurenine metabolic process (GO:0070189)5.67294178
11triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.53463514
12bile acid biosynthetic process (GO:0006699)5.53307825
13negative regulation of fibrinolysis (GO:0051918)5.53265354
14tryptophan metabolic process (GO:0006568)5.52947334
15regulation of protein activation cascade (GO:2000257)5.50294849
16desmosome organization (GO:0002934)5.45609129
17complement activation, alternative pathway (GO:0006957)5.39099716
18regulation of fibrinolysis (GO:0051917)5.33471693
19urea metabolic process (GO:0019627)5.26343844
20urea cycle (GO:0000050)5.26343844
21peptidyl-glutamic acid carboxylation (GO:0017187)5.22991733
22protein carboxylation (GO:0018214)5.22991733
23regulation of complement activation (GO:0030449)5.21316127
24glyoxylate metabolic process (GO:0046487)5.20563024
25alpha-linolenic acid metabolic process (GO:0036109)5.16857782
26cysteine metabolic process (GO:0006534)5.04238532
27sulfur amino acid catabolic process (GO:0000098)5.00597813
28serine family amino acid catabolic process (GO:0009071)5.00005912
29high-density lipoprotein particle remodeling (GO:0034375)4.99034266
30cell adhesion mediated by integrin (GO:0033627)4.98029241
31homocysteine metabolic process (GO:0050667)4.96182066
32nitrogen cycle metabolic process (GO:0071941)4.76896754
33bile acid metabolic process (GO:0008206)4.76069243
34aromatic amino acid family metabolic process (GO:0009072)4.56115155
35tyrosine metabolic process (GO:0006570)4.49656393
36reverse cholesterol transport (GO:0043691)4.41491671
37acylglycerol homeostasis (GO:0055090)4.33367098
38triglyceride homeostasis (GO:0070328)4.33367098
39fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.32080471
40bile acid and bile salt transport (GO:0015721)4.30393122
41alpha-amino acid catabolic process (GO:1901606)4.26611873
42amino-acid betaine metabolic process (GO:0006577)4.24976390
43regulation of triglyceride catabolic process (GO:0010896)4.22599285
44lysine catabolic process (GO:0006554)4.22386499
45lysine metabolic process (GO:0006553)4.22386499
46cell-substrate junction assembly (GO:0007044)4.17723691
47plasma lipoprotein particle remodeling (GO:0034369)4.15380316
48protein-lipid complex remodeling (GO:0034368)4.15380316
49macromolecular complex remodeling (GO:0034367)4.15380316
50glycine metabolic process (GO:0006544)4.14600943
51indolalkylamine metabolic process (GO:0006586)4.06906264
52amine catabolic process (GO:0009310)4.05546172
53cellular biogenic amine catabolic process (GO:0042402)4.05546172
54imidazole-containing compound metabolic process (GO:0052803)3.97449314
55regulation of cholesterol esterification (GO:0010872)3.97173530
56endodermal cell differentiation (GO:0035987)3.92402572
57phospholipid efflux (GO:0033700)3.92213142
58skin morphogenesis (GO:0043589)3.91691506
59fibrinolysis (GO:0042730)3.91235490
60cellular glucuronidation (GO:0052695)3.90733030
61plasma lipoprotein particle clearance (GO:0034381)3.89849324
62arginine metabolic process (GO:0006525)3.89025365
63negative regulation of cholesterol transport (GO:0032375)3.88690650
64negative regulation of sterol transport (GO:0032372)3.88690650
65cellular amino acid catabolic process (GO:0009063)3.88214086
66negative regulation of keratinocyte proliferation (GO:0010839)3.84909246
67positive regulation of fatty acid beta-oxidation (GO:0032000)3.84499009
68regulation of transforming growth factor beta2 production (GO:0032909)3.84455012
69serine family amino acid metabolic process (GO:0009069)3.82370879
70coenzyme catabolic process (GO:0009109)3.76063821
71benzene-containing compound metabolic process (GO:0042537)3.75020782
72cytolysis (GO:0019835)3.73208362
73regulation of plasminogen activation (GO:0010755)3.73176492
74ethanol oxidation (GO:0006069)3.70505121
75regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.70091838
76cholesterol efflux (GO:0033344)3.69368250
77midgut development (GO:0007494)3.68884963
78glutamate metabolic process (GO:0006536)3.68799374
79bundle of His cell to Purkinje myocyte communication (GO:0086069)3.65834733
80cellular ketone body metabolic process (GO:0046950)3.65829232
81paraxial mesoderm development (GO:0048339)3.65787393
82regulation of bile acid biosynthetic process (GO:0070857)3.62689376
83negative regulation of lipase activity (GO:0060192)3.61874235
84cellular modified amino acid catabolic process (GO:0042219)3.60998679
85epoxygenase P450 pathway (GO:0019373)3.57447137
86phospholipid homeostasis (GO:0055091)3.55632807
87complement activation, classical pathway (GO:0006958)3.53889703
88gap junction assembly (GO:0016264)3.53250297
89complement activation (GO:0006956)3.51366628
90blood coagulation, intrinsic pathway (GO:0007597)3.51102289
91positive regulation of lipid catabolic process (GO:0050996)3.49056725
92protein activation cascade (GO:0072376)3.47880694
93drug catabolic process (GO:0042737)3.47767099
94negative regulation of protein activation cascade (GO:2000258)3.45382622
95regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.45239777
96serine family amino acid biosynthetic process (GO:0009070)3.44419966
97dicarboxylic acid biosynthetic process (GO:0043650)3.44270194
98glucuronate metabolic process (GO:0019585)3.43229527
99uronic acid metabolic process (GO:0006063)3.43229527
100cholesterol homeostasis (GO:0042632)3.42750813
101plasma lipoprotein particle assembly (GO:0034377)3.39310908
102sterol homeostasis (GO:0055092)3.38752202
103organic acid catabolic process (GO:0016054)3.36007116
104carboxylic acid catabolic process (GO:0046395)3.36007116
105regulation of cholesterol homeostasis (GO:2000188)3.34315932
106lipoprotein metabolic process (GO:0042157)3.33761041
107chondrocyte proliferation (GO:0035988)3.33373135
108response to nitrosative stress (GO:0051409)3.33047519
109low-density lipoprotein particle remodeling (GO:0034374)3.29562297
110dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.28122852
111surfactant homeostasis (GO:0043129)3.25049070
112aldehyde catabolic process (GO:0046185)3.23946476
113very-low-density lipoprotein particle assembly (GO:0034379)3.22672690
114positive regulation of lipoprotein lipase activity (GO:0051006)3.21737412
115positive regulation of triglyceride lipase activity (GO:0061365)3.21737412
116regulation of branching involved in salivary gland morphogenesis (GO:0060693)3.21417379
117collagen fibril organization (GO:0030199)3.19366195
118negative regulation of chondrocyte differentiation (GO:0032331)3.19300854
119acetyl-CoA metabolic process (GO:0006084)3.18364812
120COPII vesicle coating (GO:0048208)3.17327829
121ketone body metabolic process (GO:1902224)3.16207268
122Golgi transport vesicle coating (GO:0048200)3.16103941
123COPI coating of Golgi vesicle (GO:0048205)3.16103941
124keratinocyte proliferation (GO:0043616)3.14420745
125negative regulation of fatty acid transport (GO:2000192)3.00461027
126basement membrane organization (GO:0071711)2.97969808
127omega-hydroxylase P450 pathway (GO:0097267)2.97430006
128retina vasculature morphogenesis in camera-type eye (GO:0061299)2.96614515
129mesodermal cell differentiation (GO:0048333)2.91022782
130regulation of keratinocyte proliferation (GO:0010837)2.90490199
131cell migration involved in sprouting angiogenesis (GO:0002042)2.84445124
132epithelial cell-cell adhesion (GO:0090136)2.83588449
133exogenous drug catabolic process (GO:0042738)2.79666472
134hippo signaling (GO:0035329)2.78856797
135establishment of tissue polarity (GO:0007164)2.75966284
136establishment of planar polarity (GO:0001736)2.75966284
137sequestering of extracellular ligand from receptor (GO:0035581)2.74907563
138chemical homeostasis within a tissue (GO:0048875)2.72584985
139endothelial cell morphogenesis (GO:0001886)2.71082747
140cell-substrate adherens junction assembly (GO:0007045)2.70507230
141focal adhesion assembly (GO:0048041)2.70507230
142adherens junction assembly (GO:0034333)2.68539048
143maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.65996098
144positive regulation of endothelial cell apoptotic process (GO:2000353)2.64553900
145polarized epithelial cell differentiation (GO:0030859)2.64035809
146planar cell polarity pathway involved in neural tube closure (GO:0090179)2.61887508
147substrate-dependent cell migration (GO:0006929)2.60042197
148protein retention in ER lumen (GO:0006621)2.59928336
149wound healing, spreading of epidermal cells (GO:0035313)2.59788830
150daunorubicin metabolic process (GO:0044597)2.58272291
151polyketide metabolic process (GO:0030638)2.58272291
152doxorubicin metabolic process (GO:0044598)2.58272291
153extracellular matrix disassembly (GO:0022617)2.57002103
154negative regulation of wound healing (GO:0061045)2.56848642
155intestinal cholesterol absorption (GO:0030299)2.56439454
156regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.54826750
157notochord development (GO:0030903)2.50838945
158positive regulation of extracellular matrix organization (GO:1903055)2.48467535
159cell migration involved in heart development (GO:0060973)2.46685101
160collagen metabolic process (GO:0032963)2.45737393
161mesenchymal-epithelial cell signaling (GO:0060638)2.43794985
162regulation of water loss via skin (GO:0033561)2.43570109
163regulation of transforming growth factor beta1 production (GO:0032908)2.42946163
164anterior/posterior axis specification, embryo (GO:0008595)2.41316287
165regulation of cardioblast differentiation (GO:0051890)2.40873733
166regulation of transforming growth factor beta production (GO:0071634)2.40725432
167atrioventricular valve morphogenesis (GO:0003181)2.36872539
168smooth muscle tissue development (GO:0048745)2.36473618
169cell junction assembly (GO:0034329)2.36090897
170cellular response to vitamin D (GO:0071305)2.34462749
171negative regulation of hemostasis (GO:1900047)2.34180752
172negative regulation of blood coagulation (GO:0030195)2.34180752
173kidney mesenchyme development (GO:0072074)2.33665455
174glomerular basement membrane development (GO:0032836)2.33324680
175positive regulation of hemostasis (GO:1900048)2.33242188
176positive regulation of blood coagulation (GO:0030194)2.33242188
177multicellular organismal macromolecule metabolic process (GO:0044259)2.33218730
178protein localization to endosome (GO:0036010)2.32511766
179substrate adhesion-dependent cell spreading (GO:0034446)2.32494357
180hypotonic response (GO:0006971)2.32456855
181vascular endothelial growth factor signaling pathway (GO:0038084)2.31789795

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse7.14174569
2PPARA_22158963_ChIP-Seq_LIVER_Mouse6.05281493
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.00852058
4LXR_22158963_ChIP-Seq_LIVER_Mouse5.79444727
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.48819186
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.09261655
7* NR1I2_20693526_ChIP-Seq_LIVER_Mouse4.02032868
8SMAD4_19686287_ChIP-ChIP_HaCaT_Human3.95552380
9CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.93924074
10CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.86896891
11CLOCK_20551151_ChIP-Seq_293T_Human2.40750637
12SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.34914341
13SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.34914341
14HIF1A_21447827_ChIP-Seq_MCF-7_Human2.01052795
15ESR1_17901129_ChIP-ChIP_LIVER_Mouse10.1300293
16TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.93762110
17GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.87822860
18* TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.76229965
19SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.70772760
20* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.70630682
21* FOXA2_19822575_ChIP-Seq_HepG2_Human1.67870448
22HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.64179300
23TRIM28_21343339_ChIP-Seq_HEK293_Human1.63730697
24ESR1_15608294_ChIP-ChIP_MCF-7_Human1.61924175
25RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.57418579
26TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.54601141
27STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.51174644
28RARG_19884340_ChIP-ChIP_MEFs_Mouse1.50947255
29TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.50306967
30SALL4_18804426_ChIP-ChIP_XEN_Mouse1.47784273
31SMAD_19615063_ChIP-ChIP_OVARY_Human1.47410404
32SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.42825980
33SALL1_21062744_ChIP-ChIP_HESCs_Human1.41355449
34* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.39976730
35TP63_23658742_ChIP-Seq_EP156T_Human1.33323547
36PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.32582986
37TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.32406480
38UBF1/2_26484160_Chip-Seq_HMECs_Human1.31834669
39* HNF4A_19822575_ChIP-Seq_HepG2_Human1.30962126
40ESR1_21235772_ChIP-Seq_MCF-7_Human1.24086583
41P300_27058665_Chip-Seq_ZR-75-30cells_Human1.23970826
42* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.23755165
43TP53_16413492_ChIP-PET_HCT116_Human1.23673026
44ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.21534129
45* EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.20828280
46HTT_18923047_ChIP-ChIP_STHdh_Human1.20256954
47ESR2_21235772_ChIP-Seq_MCF-7_Human1.18630990
48P63_26484246_Chip-Seq_KERATINOCYTES_Human1.15835316
49RBPJ_22232070_ChIP-Seq_NCS_Mouse1.15154995
50GATA1_22025678_ChIP-Seq_K562_Human1.14161875
51PPAR_26484153_Chip-Seq_NCI-H1993_Human1.11606366
52GATA2_21666600_ChIP-Seq_HMVEC_Human1.09124857
53GATA4_25053715_ChIP-Seq_YYC3_Human1.08910449
54NRF2_20460467_ChIP-Seq_MEFs_Mouse1.07118546
55NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.07118546
56ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.06940750
57* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.06855162
58PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.06010932
59ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.05292392
60PIAS1_25552417_ChIP-Seq_VCAP_Human1.04046193
61* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.03654378
62* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.03167672
63ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.00997473
64* ATF3_27146783_Chip-Seq_COLON_Human1.00716173
65TP63_17297297_ChIP-ChIP_HaCaT_Human0.99347933
66ESR1_20079471_ChIP-ChIP_T-47D_Human0.99296738
67STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.98595449
68* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.98499969
69EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.98187047
70FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.97643073
71CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.97440516
72SOX2_27498859_Chip-Seq_STOMACH_Mouse0.97362403
73TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.96660582
74HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.95368719
75BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.95268091
76* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94474741
77GATA6_25053715_ChIP-Seq_YYC3_Human0.92507568
78* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.90737205
79BCAT_22108803_ChIP-Seq_LS180_Human0.89330640
80WT1_19549856_ChIP-ChIP_CCG9911_Human0.88509302
81STAT6_21828071_ChIP-Seq_BEAS2B_Human0.85811804
82PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.85348134
83* AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.83528548
84ISL1_27105846_Chip-Seq_CPCs_Mouse0.83292552
85NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.82306878
86* CJUN_26792858_Chip-Seq_BT549_Human0.80890569
87RXRA_24833708_ChIP-Seq_LIVER_Mouse0.79845023
88ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.76872177
89CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.76458908
90EP300_21415370_ChIP-Seq_HL-1_Mouse0.76331647
91* CDX2_20551321_ChIP-Seq_CACO-2_Human0.75784016
92FOXO3_23340844_ChIP-Seq_DLD1_Human0.74260526
93* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.73539618
94* SOX2_20726797_ChIP-Seq_SW620_Human0.70746923
95PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.69902904
96ZNF263_19887448_ChIP-Seq_K562_Human0.69269299
97AUTS2_25519132_ChIP-Seq_293T-REX_Human0.68567343
98TCF3_18692474_ChIP-Seq_MEFs_Mouse0.68208715
99FOXM1_26456572_ChIP-Seq_MCF-7_Human0.67152303
100SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.66120256
101AHR_22903824_ChIP-Seq_MCF-7_Human0.66053352
102TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.65968966
103TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.64784276
104KAP1_22055183_ChIP-Seq_ESCs_Mouse0.64480803
105FOXA1_25552417_ChIP-Seq_VCAP_Human0.63786439
106SOX9_24532713_ChIP-Seq_HFSC_Mouse0.63376921
107EED_16625203_ChIP-ChIP_MESCs_Mouse0.62894092
108NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.61723850
109NR3C1_21868756_ChIP-Seq_MCF10A_Human0.61265125
110CDX2_22108803_ChIP-Seq_LS180_Human0.60284936
111FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.60275172
112TCF3_18692474_ChIP-Seq_MESCs_Mouse0.58184463
113ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.58158064
114TP53_18474530_ChIP-ChIP_U2OS_Human0.58151335
115FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.57988820
116CDX2_19796622_ChIP-Seq_MESCs_Mouse0.57545909
117PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.57216329
118NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.57215450
119* SMAD4_21741376_ChIP-Seq_HESCs_Human0.57049157
120* GATA3_24758297_ChIP-Seq_MCF-7_Human0.56805159
121AR_21909140_ChIP-Seq_LNCAP_Human0.56656586
122* BRD4_25478319_ChIP-Seq_HGPS_Human0.56244477
123POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.56149333
124SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.56118335
125* ARNT_22903824_ChIP-Seq_MCF-7_Human0.53929912
126* TCF4_18268006_ChIP-ChIP_LS174T_Human0.53911097
127NFIB_24661679_ChIP-Seq_LUNG_Mouse0.53728287
128NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.53211986
129NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.52689629
130NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.51826627
131TBX20_22328084_ChIP-Seq_HEART_Mouse0.51746121
132TBX20_22080862_ChIP-Seq_HEART_Mouse0.51746121
133ERG_21242973_ChIP-ChIP_JURKAT_Human0.51611406

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system7.38201592
2MP0005360_urolithiasis6.57748792
3MP0005085_abnormal_gallbladder_physiolo6.00388710
4MP0005365_abnormal_bile_salt5.76592847
5MP0008875_abnormal_xenobiotic_pharmacok4.27772067
6MP0003252_abnormal_bile_duct3.75634109
7MP0003941_abnormal_skin_development3.38223552
8MP0003806_abnormal_nucleotide_metabolis3.28952676
9MP0010329_abnormal_lipoprotein_level3.19697015
10MP0003566_abnormal_cell_adhesion3.06643286
11MP0010368_abnormal_lymphatic_system2.84646219
12MP0005083_abnormal_biliary_tract2.62355139
13MP0005257_abnormal_intraocular_pressure2.51679184
14MP0010352_gastrointestinal_tract_polyps2.42897816
15MP0001666_abnormal_nutrient_absorption2.34398821
16MP0003705_abnormal_hypodermis_morpholog2.31594703
17MP0009840_abnormal_foam_cell2.24256667
18MP0009780_abnormal_chondrocyte_physiolo2.22579443
19MP0005332_abnormal_amino_acid2.17306701
20MP0003950_abnormal_plasma_membrane2.14309585
21MP0000762_abnormal_tongue_morphology2.11195457
22MP0003195_calcinosis2.07129088
23MP0002138_abnormal_hepatobiliary_system2.04640861
24MP0001958_emphysema1.96989757
25MP0003868_abnormal_feces_composition1.94866195
26MP0009697_abnormal_copulation1.92983544
27MP0004019_abnormal_vitamin_homeostasis1.92969152
28MP0005623_abnormal_meninges_morphology1.91266993
29MP0009053_abnormal_anal_canal1.86592807
30MP0000467_abnormal_esophagus_morphology1.73751456
31MP0000609_abnormal_liver_physiology1.72863911
32MP0002796_impaired_skin_barrier1.70391402
33MP0002118_abnormal_lipid_homeostasis1.69601574
34MP0003191_abnormal_cellular_cholesterol1.65299549
35MP0005409_darkened_coat_color1.63036826
36MP0003279_aneurysm1.55504741
37MP0001299_abnormal_eye_distance/1.51088264
38MP0004272_abnormal_basement_membrane1.49152071
39MP0003091_abnormal_cell_migration1.46860465
40MP0001849_ear_inflammation1.43753929
41MP0005319_abnormal_enzyme/_coenzyme1.42702937
42MP0006054_spinal_hemorrhage1.31001593
43MP0010678_abnormal_skin_adnexa1.30389422
44MP0003453_abnormal_keratinocyte_physiol1.30101911
45MP0002877_abnormal_melanocyte_morpholog1.29390907
46MP0001879_abnormal_lymphatic_vessel1.28295043
47MP0008438_abnormal_cutaneous_collagen1.25676263
48MP0005248_abnormal_Harderian_gland1.24313157
49MP0009384_cardiac_valve_regurgitation1.23647372
50MP0001216_abnormal_epidermal_layer1.21173815
51MP0000537_abnormal_urethra_morphology1.19138632
52MP0005501_abnormal_skin_physiology1.18866497
53MP0005408_hypopigmentation1.16105560
54MP0000013_abnormal_adipose_tissue1.12060287
55MP0005647_abnormal_sex_gland1.11716392
56MP0009250_abnormal_appendicular_skeleto1.07938936
57MP0005187_abnormal_penis_morphology1.07009504
58MP0005197_abnormal_uvea_morphology1.06852455
59MP0003755_abnormal_palate_morphology1.06054662
60MP0001764_abnormal_homeostasis1.05535043
61MP0005508_abnormal_skeleton_morphology1.04288393
62MP0005451_abnormal_body_composition1.03951070
63MP0005220_abnormal_exocrine_pancreas1.03688657
64MP0002234_abnormal_pharynx_morphology1.01906915
65MP0000383_abnormal_hair_follicle1.01387104
66MP0000598_abnormal_liver_morphology0.98696616
67MP0002254_reproductive_system_inflammat0.97750877
68MP0000566_synostosis0.97306412
69MP0005084_abnormal_gallbladder_morpholo0.96009317
70MP0010771_integument_phenotype0.95627702
71MP0009643_abnormal_urine_homeostasis0.92458390
72MP0001661_extended_life_span0.92396828
73MP0003011_delayed_dark_adaptation0.90055182
74MP0004782_abnormal_surfactant_physiolog0.89599890
75MP0000432_abnormal_head_morphology0.88032693
76MP0000428_abnormal_craniofacial_morphol0.87712908
77MP0002108_abnormal_muscle_morphology0.87198842
78MP0001243_abnormal_dermal_layer0.86563009
79MP0000003_abnormal_adipose_tissue0.85593144
80MP0000377_abnormal_hair_follicle0.85208311
81MP0000627_abnormal_mammary_gland0.84500383
82MP0004233_abnormal_muscle_weight0.83037996
83MP0005275_abnormal_skin_tensile0.82952908
84MP0000733_abnormal_muscle_development0.82940215
85MP0002249_abnormal_larynx_morphology0.82530073
86MP0005670_abnormal_white_adipose0.81497540
87MP0005076_abnormal_cell_differentiation0.81010251
88MP0005584_abnormal_enzyme/coenzyme_acti0.79973603
89MP0010030_abnormal_orbit_morphology0.78482522
90MP0005164_abnormal_response_to0.75342055
91MP0005193_abnormal_anterior_eye0.74613064
92MP0002697_abnormal_eye_size0.74431436
93MP0003186_abnormal_redox_activity0.74143774
94MP0002084_abnormal_developmental_patter0.70873148
95MP0009764_decreased_sensitivity_to0.70855349
96MP0000767_abnormal_smooth_muscle0.70023759
97MP0009763_increased_sensitivity_to0.69851069
98MP0005395_other_phenotype0.69553841
99MP0003283_abnormal_digestive_organ0.69329920
100MP0002089_abnormal_postnatal_growth/wei0.68736260
101MP0005167_abnormal_blood-brain_barrier0.68124420
102MP0000163_abnormal_cartilage_morphology0.68111719
103MP0004858_abnormal_nervous_system0.67994339
104MP0009672_abnormal_birth_weight0.67393910
105MP0005503_abnormal_tendon_morphology0.66545262
106MP0010234_abnormal_vibrissa_follicle0.65912697
107MP0003718_maternal_effect0.65714296
108MP0002295_abnormal_pulmonary_circulatio0.65630719
109MP0003890_abnormal_embryonic-extraembry0.65006309
110MP0001756_abnormal_urination0.64979761
111MP0002282_abnormal_trachea_morphology0.62423557
112MP0002060_abnormal_skin_morphology0.62090586
113MP0003115_abnormal_respiratory_system0.62004331
114MP0000579_abnormal_nail_morphology0.61756067
115MP0002098_abnormal_vibrissa_morphology0.59621320
116MP0006138_congestive_heart_failure0.58075154
117MP0004264_abnormal_extraembryonic_tissu0.55330503
118MP0003119_abnormal_digestive_system0.55257531
119MP0002896_abnormal_bone_mineralization0.54578293
120MP0005376_homeostasis/metabolism_phenot0.54471545
121MP0002168_other_aberrant_phenotype0.54380428
122MP0005595_abnormal_vascular_smooth0.54362006
123MP0009642_abnormal_blood_homeostasis0.54102528
124MP0003942_abnormal_urinary_system0.52710817
125MP0000462_abnormal_digestive_system0.51821053
126MP0002233_abnormal_nose_morphology0.51774705
127MP0002128_abnormal_blood_circulation0.51446128
128MP0005334_abnormal_fat_pad0.51175515
129MP0004883_abnormal_blood_vessel0.51165998
130MP0005023_abnormal_wound_healing0.51018725
131MP0000647_abnormal_sebaceous_gland0.50583468
132MP0000639_abnormal_adrenal_gland0.50453657
133MP0000516_abnormal_urinary_system0.50241694
134MP0005367_renal/urinary_system_phenotyp0.50241694
135MP0002928_abnormal_bile_duct0.49934518
136MP0003935_abnormal_craniofacial_develop0.49481439
137MP0002092_abnormal_eye_morphology0.49333017
138MP0003937_abnormal_limbs/digits/tail_de0.48860115
139MP0003385_abnormal_body_wall0.48387753
140MP0001915_intracranial_hemorrhage0.48376190
141MP0005666_abnormal_adipose_tissue0.47484923
142MP0001270_distended_abdomen0.47226304
143MP0001542_abnormal_bone_strength0.47173097
144MP0002078_abnormal_glucose_homeostasis0.46775024
145MP0002971_abnormal_brown_adipose0.46377091
146MP0000534_abnormal_ureter_morphology0.45803265
147MP0004130_abnormal_muscle_cell0.45165517

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)7.44732369
2Intrahepatic cholestasis (HP:0001406)7.11535796
3Abnormality of monocarboxylic acid metabolism (HP:0010996)6.33444157
4Abnormality of aromatic amino acid family metabolism (HP:0004338)6.14704735
5Prolonged partial thromboplastin time (HP:0003645)6.05417763
6Hypobetalipoproteinemia (HP:0003563)5.74187623
7Xanthomatosis (HP:0000991)5.65515044
8Complement deficiency (HP:0004431)5.54946582
9Premature rupture of membranes (HP:0001788)5.26593617
10Atrophic scars (HP:0001075)5.07820603
11Hyperlipoproteinemia (HP:0010980)4.90217890
12Epidermoid cyst (HP:0200040)4.52244656
13Hypolipoproteinemia (HP:0010981)4.47757806
14Hyperglycinemia (HP:0002154)4.44011247
15Joint hemorrhage (HP:0005261)4.28333788
16Abnormality of the common coagulation pathway (HP:0010990)4.13927132
17Hypoalphalipoproteinemia (HP:0003233)4.08745878
18Hyperammonemia (HP:0001987)4.06208407
19Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.05553211
20Hypoglycemic coma (HP:0001325)3.92316139
21Abnormality of sulfur amino acid metabolism (HP:0004339)3.90948338
22Abnormality of complement system (HP:0005339)3.89837909
23Hyperglycinuria (HP:0003108)3.88495549
24Fat malabsorption (HP:0002630)3.88009744
25Abnormality of the intrinsic pathway (HP:0010989)3.83436802
26Abnormality of methionine metabolism (HP:0010901)3.79313555
27Abnormality of glutamine family amino acid metabolism (HP:0010902)3.72177289
28Arterial tortuosity (HP:0005116)3.71652145
29Abnormality of serine family amino acid metabolism (HP:0010894)3.69582148
30Abnormality of glycine metabolism (HP:0010895)3.69582148
31Vascular tortuosity (HP:0004948)3.68418708
32Abnormality of aspartate family amino acid metabolism (HP:0010899)3.61295154
33Abnormality of pyrimidine metabolism (HP:0004353)3.57471484
34Conjugated hyperbilirubinemia (HP:0002908)3.57294279
35Ketosis (HP:0001946)3.57182459
36Aortic dissection (HP:0002647)3.49446319
37Fragile skin (HP:0001030)3.34862275
38Milia (HP:0001056)3.31455605
39Onycholysis (HP:0001806)3.25445771
40Hepatocellular carcinoma (HP:0001402)3.24615660
41Hypercholesterolemia (HP:0003124)3.19623633
42Esophageal varix (HP:0002040)3.17744461
43Hypochromic microcytic anemia (HP:0004840)3.02135737
44Ankle contracture (HP:0006466)2.98632679
45Aortic aneurysm (HP:0004942)2.98079048
46Follicular hyperkeratosis (HP:0007502)2.95484814
47Fragile nails (HP:0001808)2.91916853
48Abnormality of serum amino acid levels (HP:0003112)2.89895933
49Steatorrhea (HP:0002570)2.83995715
50Hypoglycemic seizures (HP:0002173)2.83445062
51Plantar hyperkeratosis (HP:0007556)2.83366407
52Delayed CNS myelination (HP:0002188)2.81187384
53Skin nodule (HP:0200036)2.77694333
54Myocardial infarction (HP:0001658)2.76348208
55Abnormality of nail color (HP:0100643)2.74441394
56Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.71084619
57Spontaneous abortion (HP:0005268)2.70793781
58Abnormality of fatty-acid metabolism (HP:0004359)2.69839122
59Abnormality of nucleobase metabolism (HP:0010932)2.68597081
60Spastic diplegia (HP:0001264)2.66870378
61Natal tooth (HP:0000695)2.65819044
62Pterygium (HP:0001059)2.65670269
63Ketoacidosis (HP:0001993)2.65249719
64Bladder diverticulum (HP:0000015)2.63219917
65Soft skin (HP:0000977)2.59840845
66Shallow orbits (HP:0000586)2.59216553
67Vascular calcification (HP:0004934)2.58524296
68Cardiovascular calcification (HP:0011915)2.53790622
69Alopecia of scalp (HP:0002293)2.51572723
70Hyperbilirubinemia (HP:0002904)2.48200662
71Abnormality of dentin (HP:0010299)2.48057144
72Cervical subluxation (HP:0003308)2.46951107
73Enlarged kidneys (HP:0000105)2.46924111
74Mitral stenosis (HP:0001718)2.41833380
75Hyperglycemia (HP:0003074)2.41661735
76Osteolytic defects of the hand bones (HP:0009699)2.37139165
77Osteolytic defects of the phalanges of the hand (HP:0009771)2.37139165
78Thick nail (HP:0001805)2.37012842
79Neonatal short-limb short stature (HP:0008921)2.35551075
80Short nail (HP:0001799)2.33103513
81Wormian bones (HP:0002645)2.31384853
82Spinal rigidity (HP:0003306)2.28669341
83Broad metatarsal (HP:0001783)2.28533745
84Coronal craniosynostosis (HP:0004440)2.26214299
85Popliteal pterygium (HP:0009756)2.25825187
86Hyperinsulinemic hypoglycemia (HP:0000825)2.24912697
87Abnormality of purine metabolism (HP:0004352)2.24159879
88Gout (HP:0001997)2.19708849
89Advanced eruption of teeth (HP:0006288)2.19327523
90Systemic lupus erythematosus (HP:0002725)2.17182127
91Malnutrition (HP:0004395)2.15733426
92Metabolic acidosis (HP:0001942)2.15299232
93Mitral valve prolapse (HP:0001634)2.13777319
94Overgrowth (HP:0001548)2.13001896
95Hepatoblastoma (HP:0002884)2.11424301
96Nail dystrophy (HP:0008404)2.10134376
97Abnormal delivery (HP:0001787)2.08851058
98Ankyloglossia (HP:0010296)2.08397033
99Blue sclerae (HP:0000592)2.05191783
100Lymphangioma (HP:0100764)2.04828598
101Palmoplantar hyperkeratosis (HP:0000972)2.03540886
102Glomerulonephritis (HP:0000099)2.02883476
103Abnormal cartilage morphology (HP:0002763)2.02329775
104Asymmetry of the thorax (HP:0001555)2.01960802
105Selective tooth agenesis (HP:0001592)2.01178808
106Vertebral arch anomaly (HP:0008438)2.01142298
107Abnormality of carpal bone ossification (HP:0006257)2.00228158
108Abnormality of dicarboxylic acid metabolism (HP:0010995)1.99809216
109Dicarboxylic aciduria (HP:0003215)1.99809216
110Cerebral aneurysm (HP:0004944)1.99377354
111Ulnar bowing (HP:0003031)1.99123822
112Ridged nail (HP:0001807)1.98634837
113Hemorrhage of the eye (HP:0011885)1.98486009
114Lethargy (HP:0001254)1.98296437
115Palmar hyperkeratosis (HP:0010765)1.97750363
116Abnormality of the acetabulum (HP:0003170)1.92588066
117Neonatal onset (HP:0003623)1.92136457
118Hypophosphatemic rickets (HP:0004912)1.87449706
119Hypoplasia of dental enamel (HP:0006297)1.86434531
120Stroke (HP:0001297)1.86315146
121Turricephaly (HP:0000262)1.85514117
122Mildly elevated creatine phosphokinase (HP:0008180)1.84913880
123Rickets (HP:0002748)1.83238049
124Polycythemia (HP:0001901)1.82006618
125Joint laxity (HP:0001388)1.80619559
126Spondylolisthesis (HP:0003302)1.79308734
127Absent eyelashes (HP:0000561)1.77734433
128Abnormal ossification of hand bones (HP:0005921)1.76984011
129Symptomatic seizures (HP:0011145)1.76579522
130Irritability (HP:0000737)1.76061663
131Thrombophlebitis (HP:0004418)1.75428665
132Elbow flexion contracture (HP:0002987)1.75020817
133Abnormal gallbladder morphology (HP:0012437)1.74624361
134Renal cortical cysts (HP:0000803)1.74155831
135Tibial bowing (HP:0002982)1.73568647
136Absent frontal sinuses (HP:0002688)1.73450868
137Abnormality of oral frenula (HP:0000190)1.72964529
138Abnormality of proline metabolism (HP:0010907)1.72874172
139Hydroxyprolinuria (HP:0003080)1.72874172
140Neoplasm of the liver (HP:0002896)1.72102297
141Syringomyelia (HP:0003396)1.71317954
142Spinal cord lesions (HP:0100561)1.71317954
143Genu recurvatum (HP:0002816)1.71308799
144Back pain (HP:0003418)1.71116171
145Vertebral compression fractures (HP:0002953)1.71026132
146Chorioretinal atrophy (HP:0000533)1.70898250
147Hyperextensible skin (HP:0000974)1.70238402
148Abnormality of the Achilles tendon (HP:0005109)1.69177511
149Dilatation of the ascending aorta (HP:0005111)1.68630678
150Pseudobulbar signs (HP:0002200)1.68389731
151Flat acetabular roof (HP:0003180)1.67948969
152Type 1 muscle fiber predominance (HP:0003803)1.67789208
153Cholelithiasis (HP:0001081)1.67069351
154Nephritis (HP:0000123)1.66262569
155Acanthocytosis (HP:0001927)1.66131957
156Brushfield spots (HP:0001088)1.65541492
157Menorrhagia (HP:0000132)1.64789799
158Wrist flexion contracture (HP:0001239)1.63955815
159Knee flexion contracture (HP:0006380)1.63264784
160Bowel diverticulosis (HP:0005222)1.62997662
161Pancreatitis (HP:0001733)1.62565241
162Hypotrichosis (HP:0001006)1.62391372
163Microglossia (HP:0000171)1.61645905
164Thin bony cortex (HP:0002753)1.60846486
165Recurrent gram-negative bacterial infections (HP:0005420)1.60003877
166Abnormal enzyme/coenzyme activity (HP:0012379)1.59135243
167Aneurysm (HP:0002617)1.58943806
168Protrusio acetabuli (HP:0003179)1.58375923
169Abnormal hand bone ossification (HP:0010660)1.58153914
170Wide anterior fontanel (HP:0000260)1.58027126
171Abnormality of the pancreatic islet cells (HP:0006476)1.57723655
172Abnormality of endocrine pancreas physiology (HP:0012093)1.57723655
173Spinal cord compression (HP:0002176)1.56287122
174Sensorimotor neuropathy (HP:0007141)1.56163168
175Coxa vara (HP:0002812)1.55272972
176Right ventricular cardiomyopathy (HP:0011663)1.55123876
177Abnormality of the gallbladder (HP:0005264)1.54990145
178Pancreatic islet-cell hyperplasia (HP:0004510)1.54899798
179Hypoplastic labia majora (HP:0000059)1.54808225
180Respiratory distress (HP:0002098)1.53145140
181Protruding ear (HP:0000411)1.52012259

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE14.08380507
2LATS13.96747311
3BCKDK3.52225727
4SIK13.42994169
5INSRR3.14701384
6FGFR43.09460223
7EPHB22.88787575
8FRK2.65749822
9ERBB42.41399357
10AKT32.36196164
11FGFR22.33929058
12NTRK12.30186434
13KDR2.20388295
14STK38L2.16121175
15ERN12.12045610
16EPHA22.03769872
17PDGFRA1.96697223
18LMTK21.94776477
19PTK61.81527778
20TGFBR21.79330873
21CAMK1D1.66620746
22SCYL21.62711207
23MAP3K91.61806823
24MAP3K121.61600660
25LATS21.57717998
26NEK91.50087409
27EPHA31.48230073
28ERBB21.46747840
29STK241.41411067
30FER1.38157253
31MST1R1.33986232
32DDR21.33268161
33NUAK11.33218194
34STK31.33090377
35PIK3CG1.29245445
36TESK11.29047726
37PKN21.26059983
38PBK1.25700533
39CAMK1G1.25351404
40GRK11.24163664
41PTK21.19595775
42LIMK11.14300556
43TRPM71.14164032
44RIPK11.13770391
45TGFBR11.08230399
46TAOK31.06893365
47CDK61.06342035
48MAP2K41.06226460
49MET1.05579861
50TRIB31.05551557
51STK381.05231565
52MAPK111.04650523
53ARAF1.02297542
54MYLK1.01369864
55ERBB31.00208682
56PRKAA20.99324922
57FGFR10.92311953
58PNCK0.91869142
59MTOR0.88128709
60DAPK20.86671898
61MOS0.82431805
62NEK10.82198294
63KSR10.80168173
64MAP2K10.78945995
65GSK3A0.78112725
66MAPK150.76973198
67MAP3K30.75699131
68FGFR30.75546501
69DMPK0.75504129
70PAK30.74830498
71PRKAA10.73744669
72ABL20.72464512
73EPHB10.71646229
74PAK20.69916631
75DYRK1B0.68704270
76TAF10.68459672
77CSNK1G10.67733116
78SMG10.65972284
79ILK0.65892670
80IRAK30.65277395
81CSNK1A1L0.64934250
82FLT30.63599646
83SGK20.63088153
84CDK80.61229914
85MAPK70.61019316
86TSSK60.60092892
87EEF2K0.59954742
88PRKCZ0.59904219
89SGK30.59342988
90IGF1R0.58770570
91ROCK20.57460235
92BRSK20.56413218
93RPS6KA20.54929354
94PLK40.54198944
95TTN0.52548906
96EIF2AK10.52377909
97RPS6KB20.51971670
98MAP3K60.51219748
99KSR20.51188888
100MAP2K20.50348646
101MAPKAPK30.50066887
102PRKCE0.47787283
103PRKD20.47311290
104PRKG20.46816764
105BCR0.46258599
106MAP3K100.45853781
107MAP3K70.44483786
108PIK3CA0.44077916
109EIF2AK20.43586212
110ZAK0.43567625
111MUSK0.43556196
112STK390.43269817
113PDGFRB0.42896001
114RET0.42741434
115ICK0.42473969
116ROCK10.41761062
117CDC42BPA0.41603472
118PRKACG0.41111528
119MAP3K20.39051881
120EIF2AK30.37328863
121NEK60.35301713
122JAK20.34480508
123CAMK40.34354054
124EPHA40.34012211
125BRAF0.33988047
126MELK0.33851536
127CDK70.32673627
128CSNK1G30.31532484
129CDK120.31106409
130CDK90.31007824
131PAK40.30711066
132AKT20.29798566
133MAPK40.29145409
134PIM20.29104676
135INSR0.29008286
136CHUK0.28869881
137SGK4940.28561550
138SGK2230.28561550
139CSNK1E0.28469250
140CSNK1G20.27732649
141CAMK2G0.26750268
142AURKB0.26720235
143EGFR0.26712281
144TTK0.24800552
145JAK10.24430447
146PRKACB0.23198599

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.59531323
2Nitrogen metabolism_Homo sapiens_hsa009103.72601847
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.22014086
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.13451002
5Arginine biosynthesis_Homo sapiens_hsa002203.10707277
6Complement and coagulation cascades_Homo sapiens_hsa046102.95957140
7Tryptophan metabolism_Homo sapiens_hsa003802.78375589
8Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.56732348
9Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.54097642
10Fatty acid degradation_Homo sapiens_hsa000712.48535620
11Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.36278670
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.33383458
13Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.12702193
14Pentose and glucuronate interconversions_Homo sapiens_hsa000402.08347939
15Steroid hormone biosynthesis_Homo sapiens_hsa001402.03009598
16Butanoate metabolism_Homo sapiens_hsa006502.00468580
17Peroxisome_Homo sapiens_hsa041461.94490610
18Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.91932147
19PPAR signaling pathway_Homo sapiens_hsa033201.91913810
20Chemical carcinogenesis_Homo sapiens_hsa052041.91745155
21Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.82775427
22Retinol metabolism_Homo sapiens_hsa008301.82307662
23Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.79055460
24Propanoate metabolism_Homo sapiens_hsa006401.78140905
25Fatty acid metabolism_Homo sapiens_hsa012121.76202859
26Drug metabolism - other enzymes_Homo sapiens_hsa009831.76156569
27beta-Alanine metabolism_Homo sapiens_hsa004101.76015430
28Histidine metabolism_Homo sapiens_hsa003401.76005161
29Selenocompound metabolism_Homo sapiens_hsa004501.69942283
30Caffeine metabolism_Homo sapiens_hsa002321.69700699
31Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.66402982
32Phenylalanine metabolism_Homo sapiens_hsa003601.62000712
33Staphylococcus aureus infection_Homo sapiens_hsa051501.58132454
34Bile secretion_Homo sapiens_hsa049761.55039813
35Tyrosine metabolism_Homo sapiens_hsa003501.53631608
362-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.38529782
37Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.31617246
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.29189774
39Maturity onset diabetes of the young_Homo sapiens_hsa049501.27531913
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.25067870
41Thyroid cancer_Homo sapiens_hsa052161.24169679
42Fat digestion and absorption_Homo sapiens_hsa049751.22044583
43Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.21598441
44Sulfur metabolism_Homo sapiens_hsa009201.20049293
45Starch and sucrose metabolism_Homo sapiens_hsa005001.18538964
46Cysteine and methionine metabolism_Homo sapiens_hsa002701.18531911
47ABC transporters_Homo sapiens_hsa020101.17273511
48Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.15527715
49Tight junction_Homo sapiens_hsa045301.13958895
50Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.11847761
51Vitamin B6 metabolism_Homo sapiens_hsa007501.08207616
52Lysine degradation_Homo sapiens_hsa003101.06070348
53Biosynthesis of amino acids_Homo sapiens_hsa012301.03843622
54Pyruvate metabolism_Homo sapiens_hsa006201.03444469
55Vitamin digestion and absorption_Homo sapiens_hsa049771.02691718
56Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.00976525
57MicroRNAs in cancer_Homo sapiens_hsa052060.98935282
58Folate biosynthesis_Homo sapiens_hsa007900.97165577
59Arginine and proline metabolism_Homo sapiens_hsa003300.96544721
60Dilated cardiomyopathy_Homo sapiens_hsa054140.96347886
61Regulation of actin cytoskeleton_Homo sapiens_hsa048100.96123270
62Fatty acid elongation_Homo sapiens_hsa000620.94663903
63Carbon metabolism_Homo sapiens_hsa012000.92386065
64Steroid biosynthesis_Homo sapiens_hsa001000.91377800
65AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.90004409
66One carbon pool by folate_Homo sapiens_hsa006700.82988057
67Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.82676737
68Cyanoamino acid metabolism_Homo sapiens_hsa004600.79329600
69Axon guidance_Homo sapiens_hsa043600.79213283
70Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.71179770
71Melanoma_Homo sapiens_hsa052180.69131592
72Chronic myeloid leukemia_Homo sapiens_hsa052200.68820843
73Pathways in cancer_Homo sapiens_hsa052000.68061263
74Hedgehog signaling pathway_Homo sapiens_hsa043400.66017192
75Renal cell carcinoma_Homo sapiens_hsa052110.66002044
76Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.64438181
77Glycerolipid metabolism_Homo sapiens_hsa005610.63488063
78Sphingolipid metabolism_Homo sapiens_hsa006000.59688691
79p53 signaling pathway_Homo sapiens_hsa041150.59209809
80Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.57773563
81Glutathione metabolism_Homo sapiens_hsa004800.57220995
82Endometrial cancer_Homo sapiens_hsa052130.56823253
83Thyroid hormone signaling pathway_Homo sapiens_hsa049190.55073739
84N-Glycan biosynthesis_Homo sapiens_hsa005100.53795122
85Fatty acid biosynthesis_Homo sapiens_hsa000610.52731093
86Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.49999903
87Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.49725638
88Wnt signaling pathway_Homo sapiens_hsa043100.49604087
89Prion diseases_Homo sapiens_hsa050200.49092628
90Sulfur relay system_Homo sapiens_hsa041220.48629668
91Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.47488406
92Pancreatic cancer_Homo sapiens_hsa052120.44990623
93ErbB signaling pathway_Homo sapiens_hsa040120.44601869
94Glioma_Homo sapiens_hsa052140.44250048
95Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.42676030
96Leukocyte transendothelial migration_Homo sapiens_hsa046700.38195055
97Insulin resistance_Homo sapiens_hsa049310.38142071
98Glycosaminoglycan degradation_Homo sapiens_hsa005310.37448080
99Adherens junction_Homo sapiens_hsa045200.32344202
100Metabolic pathways_Homo sapiens_hsa011000.31697133
101Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.28912951
102Pentose phosphate pathway_Homo sapiens_hsa000300.28850898
103ECM-receptor interaction_Homo sapiens_hsa045120.28344371
104Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.28130469
105Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.25564302
106Ovarian steroidogenesis_Homo sapiens_hsa049130.21921812
107Basal cell carcinoma_Homo sapiens_hsa052170.21777673
108Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.20072720
109alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.19601382
110Adipocytokine signaling pathway_Homo sapiens_hsa049200.18860067
111AMPK signaling pathway_Homo sapiens_hsa041520.17348987
112Glucagon signaling pathway_Homo sapiens_hsa049220.15854729
113Linoleic acid metabolism_Homo sapiens_hsa005910.15661148
114Glycerophospholipid metabolism_Homo sapiens_hsa005640.14861453
115Protein digestion and absorption_Homo sapiens_hsa049740.11278728
116TGF-beta signaling pathway_Homo sapiens_hsa043500.10358732
117Hippo signaling pathway_Homo sapiens_hsa043900.10220883
118Focal adhesion_Homo sapiens_hsa045100.08350194
119Galactose metabolism_Homo sapiens_hsa000520.04057588
120Fructose and mannose metabolism_Homo sapiens_hsa000510.03320411
121Amoebiasis_Homo sapiens_hsa051460.02975169
122Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.02268748
123Bladder cancer_Homo sapiens_hsa052190.01840008
124Proteoglycans in cancer_Homo sapiens_hsa05205-0.0520323
125Prostate cancer_Homo sapiens_hsa05215-0.0463038
126PI3K-Akt signaling pathway_Homo sapiens_hsa04151-0.0449058
127Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.0364639
128Regulation of autophagy_Homo sapiens_hsa04140-0.0326074
129Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.0257507
130Small cell lung cancer_Homo sapiens_hsa05222-0.0218343
131Insulin signaling pathway_Homo sapiens_hsa04910-0.0218251
132Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.0158203

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »