Rank | Gene Set | Z-score |
---|---|---|
1 | glomerular visceral epithelial cell development (GO:0072015) | 5.66820813 |
2 | glomerular epithelial cell development (GO:0072310) | 5.15189446 |
3 | glomerular basement membrane development (GO:0032836) | 4.83079021 |
4 | intestinal cholesterol absorption (GO:0030299) | 4.74336689 |
5 | angiotensin maturation (GO:0002003) | 4.53259348 |
6 | intestinal absorption (GO:0050892) | 4.51961974 |
7 | hemidesmosome assembly (GO:0031581) | 4.42437652 |
8 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 4.22522344 |
9 | virion attachment to host cell (GO:0019062) | 4.16395534 |
10 | adhesion of symbiont to host cell (GO:0044650) | 4.16395534 |
11 | Golgi transport vesicle coating (GO:0048200) | 4.05272254 |
12 | COPI coating of Golgi vesicle (GO:0048205) | 4.05272254 |
13 | protein localization to endosome (GO:0036010) | 3.86048836 |
14 | mesodermal cell differentiation (GO:0048333) | 3.59374940 |
15 | adhesion of symbiont to host (GO:0044406) | 3.56747721 |
16 | epithelial cell-cell adhesion (GO:0090136) | 3.52372362 |
17 | NADH metabolic process (GO:0006734) | 3.46818485 |
18 | sequestering of extracellular ligand from receptor (GO:0035581) | 3.39671184 |
19 | actin filament depolymerization (GO:0030042) | 3.39634571 |
20 | renal filtration (GO:0097205) | 3.35646773 |
21 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.31337720 |
22 | hypotonic response (GO:0006971) | 3.29886206 |
23 | cell adhesion mediated by integrin (GO:0033627) | 3.27871331 |
24 | surfactant homeostasis (GO:0043129) | 3.26302382 |
25 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 3.25009798 |
26 | positive regulation of p38MAPK cascade (GO:1900745) | 3.23427459 |
27 | regulation of extracellular matrix disassembly (GO:0010715) | 3.23333826 |
28 | intestinal epithelial cell development (GO:0060576) | 3.23229168 |
29 | multicellular organismal water homeostasis (GO:0050891) | 3.20769480 |
30 | regulation of water loss via skin (GO:0033561) | 3.12394464 |
31 | transcytosis (GO:0045056) | 3.08204114 |
32 | regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044) | 3.04323046 |
33 | endocrine process (GO:0050886) | 3.04323046 |
34 | regulation of systemic arterial blood pressure by hormone (GO:0001990) | 3.04323046 |
35 | positive regulation of pseudopodium assembly (GO:0031274) | 3.03565085 |
36 | desmosome organization (GO:0002934) | 3.02979878 |
37 | skin morphogenesis (GO:0043589) | 3.01889499 |
38 | regulation of transforming growth factor beta1 production (GO:0032908) | 3.01551569 |
39 | regulation of cholesterol homeostasis (GO:2000188) | 3.00533703 |
40 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.00225236 |
41 | epoxygenase P450 pathway (GO:0019373) | 2.99694410 |
42 | response to hepatocyte growth factor (GO:0035728) | 2.95753770 |
43 | cellular response to hepatocyte growth factor stimulus (GO:0035729) | 2.95753770 |
44 | regulation of guanylate cyclase activity (GO:0031282) | 2.91293771 |
45 | negative regulation of fatty acid transport (GO:2000192) | 2.90733754 |
46 | glomerulus development (GO:0032835) | 2.90531287 |
47 | cellular glucuronidation (GO:0052695) | 2.88925017 |
48 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 2.88454968 |
49 | ethanol oxidation (GO:0006069) | 2.87272036 |
50 | myelin maintenance (GO:0043217) | 2.87092296 |
51 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.86512335 |
52 | sphingomyelin metabolic process (GO:0006684) | 2.84875330 |
53 | receptor recycling (GO:0001881) | 2.82970687 |
54 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.80092898 |
55 | lipoprotein transport (GO:0042953) | 2.79396337 |
56 | urea cycle (GO:0000050) | 2.77916338 |
57 | stress fiber assembly (GO:0043149) | 2.76863189 |
58 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.76634164 |
59 | barbed-end actin filament capping (GO:0051016) | 2.75410074 |
60 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.74218040 |
61 | renal system process involved in regulation of blood volume (GO:0001977) | 2.73814555 |
62 | regulation of systemic arterial blood pressure (GO:0003073) | 2.72125171 |
63 | tight junction assembly (GO:0070830) | 2.71690339 |
64 | fat-soluble vitamin biosynthetic process (GO:0042362) | 2.71079875 |
65 | regulation of vitamin metabolic process (GO:0030656) | 2.70787535 |
66 | glucuronate metabolic process (GO:0019585) | 2.70245627 |
67 | uronic acid metabolic process (GO:0006063) | 2.70245627 |
68 | vitamin A metabolic process (GO:0006776) | 2.69868467 |
69 | regulation of early endosome to late endosome transport (GO:2000641) | 2.69348764 |
70 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.68067546 |
71 | ethanol metabolic process (GO:0006067) | 2.65600192 |
72 | urea metabolic process (GO:0019627) | 2.64712089 |
73 | gap junction assembly (GO:0016264) | 2.64651606 |
74 | regulation of pseudopodium assembly (GO:0031272) | 2.64572529 |
75 | sulfur amino acid catabolic process (GO:0000098) | 2.64362472 |
76 | establishment of skin barrier (GO:0061436) | 2.60606409 |
77 | hormone catabolic process (GO:0042447) | 2.59401411 |
78 | regulation of glomerular filtration (GO:0003093) | 2.59040926 |
79 | positive regulation of Rho protein signal transduction (GO:0035025) | 2.58841385 |
80 | water homeostasis (GO:0030104) | 2.58378738 |
81 | macroautophagy (GO:0016236) | 2.57746816 |
82 | regulation of p38MAPK cascade (GO:1900744) | 2.57209852 |
83 | regulation of cardioblast differentiation (GO:0051890) | 2.56507312 |
84 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 2.55890749 |
85 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.55318013 |
86 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.55158356 |
87 | axon ensheathment in central nervous system (GO:0032291) | 2.54034409 |
88 | central nervous system myelination (GO:0022010) | 2.54034409 |
89 | O-glycan processing (GO:0016266) | 2.53360521 |
90 | protein heterotrimerization (GO:0070208) | 2.52489108 |
91 | asymmetric protein localization (GO:0008105) | 2.51726489 |
92 | anterior/posterior axis specification, embryo (GO:0008595) | 2.50899037 |
93 | bile acid and bile salt transport (GO:0015721) | 2.50514803 |
94 | negative regulation of protein localization to plasma membrane (GO:1903077) | 2.50363611 |
95 | peptide catabolic process (GO:0043171) | 2.50279365 |
96 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.50212637 |
97 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.49650548 |
98 | peptide hormone processing (GO:0016486) | 2.49379813 |
99 | apoptotic cell clearance (GO:0043277) | 2.46443489 |
100 | cell-cell junction assembly (GO:0007043) | 2.45574452 |
101 | glycosphingolipid catabolic process (GO:0046479) | 2.45543165 |
102 | keratan sulfate catabolic process (GO:0042340) | 2.44341072 |
103 | vesicle coating (GO:0006901) | 2.43794148 |
104 | protein retention in ER lumen (GO:0006621) | 2.43569903 |
105 | chemical homeostasis within a tissue (GO:0048875) | 2.41971902 |
106 | endocardial cushion development (GO:0003197) | 2.41431103 |
107 | glutamine family amino acid biosynthetic process (GO:0009084) | 2.41191772 |
108 | maintenance of gastrointestinal epithelium (GO:0030277) | 2.40600486 |
109 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.39082215 |
110 | positive regulation of establishment of protein localization to plasma membrane (GO:0090004) | 2.38343810 |
111 | glycolipid catabolic process (GO:0019377) | 2.38331635 |
112 | chondrocyte proliferation (GO:0035988) | 2.37755556 |
113 | endothelial cell morphogenesis (GO:0001886) | 2.37593388 |
114 | flavonoid metabolic process (GO:0009812) | 2.36981199 |
115 | proline biosynthetic process (GO:0006561) | 2.36933844 |
116 | nitrogen cycle metabolic process (GO:0071941) | 2.36631476 |
117 | basement membrane organization (GO:0071711) | 2.36367868 |
118 | regulation of bile acid biosynthetic process (GO:0070857) | 2.36250958 |
119 | oligosaccharide biosynthetic process (GO:0009312) | 2.35355218 |
120 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 2.35279154 |
121 | multicellular organismal catabolic process (GO:0044243) | 2.34379310 |
122 | atrioventricular valve morphogenesis (GO:0003181) | 2.33399736 |
123 | cell-substrate junction assembly (GO:0007044) | 2.31572172 |
124 | glutathione derivative metabolic process (GO:1901685) | 2.31552248 |
125 | glutathione derivative biosynthetic process (GO:1901687) | 2.31552248 |
126 | COPII vesicle coating (GO:0048208) | 2.31546871 |
127 | glomerular filtration (GO:0003094) | 2.31275682 |
128 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.30825285 |
129 | regulation of lipoprotein metabolic process (GO:0050746) | 2.30823131 |
130 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.30266433 |
131 | glutathione biosynthetic process (GO:0006750) | 2.29715189 |
132 | digestive system process (GO:0022600) | 2.27224368 |
133 | sulfate transmembrane transport (GO:1902358) | 2.26922302 |
134 | cellular response to vitamin D (GO:0071305) | 2.26899163 |
135 | extracellular matrix assembly (GO:0085029) | 2.26103237 |
136 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 2.25522633 |
137 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 2.25522633 |
138 | positive regulation of osteoblast proliferation (GO:0033690) | 2.25521099 |
139 | lung lobe morphogenesis (GO:0060463) | 2.25188273 |
140 | creatine metabolic process (GO:0006600) | 2.24040065 |
141 | platelet-derived growth factor receptor signaling pathway (GO:0048008) | 2.22949088 |
142 | positive regulation of protein localization to plasma membrane (GO:1903078) | 2.22432923 |
143 | endodermal cell differentiation (GO:0035987) | 2.21121990 |
144 | drug catabolic process (GO:0042737) | 2.21084757 |
145 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.21054680 |
146 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 2.20410158 |
147 | renal system process involved in regulation of systemic arterial blood pressure (GO:0003071) | 2.19906085 |
148 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 2.19491276 |
149 | multicellular organismal metabolic process (GO:0044236) | 2.18267067 |
150 | cysteine metabolic process (GO:0006534) | 2.18223798 |
151 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 2.16892996 |
152 | lung vasculature development (GO:0060426) | 2.16764292 |
153 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.16128474 |
154 | sphingosine metabolic process (GO:0006670) | 2.14792110 |
155 | multicellular organismal macromolecule metabolic process (GO:0044259) | 2.14062733 |
156 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 2.13998357 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 5.85280107 |
2 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 3.86410853 |
3 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.46602738 |
4 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.78572623 |
5 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.71452252 |
6 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 2.71047945 |
7 | * SOX2_27498859_Chip-Seq_STOMACH_Mouse | 2.54812746 |
8 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 2.41458462 |
9 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.24692644 |
10 | SOX2_20726797_ChIP-Seq_SW620_Human | 2.12893271 |
11 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 2.11744767 |
12 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 2.09013573 |
13 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.04342227 |
14 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.03979635 |
15 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 2.02150859 |
16 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.01940699 |
17 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.91715860 |
18 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.91065112 |
19 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.89528844 |
20 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.87813072 |
21 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.79559432 |
22 | * CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.77638961 |
23 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.76708232 |
24 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.76400412 |
25 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.73236707 |
26 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.67826409 |
27 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.67677717 |
28 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.64656793 |
29 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.63306253 |
30 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.61604860 |
31 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.61118476 |
32 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.60828497 |
33 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.52484832 |
34 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.49267629 |
35 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.48177094 |
36 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.43990744 |
37 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.43554776 |
38 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.43177147 |
39 | CJUN_26792858_Chip-Seq_BT549_Human | 1.42008454 |
40 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.41528495 |
41 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.40374554 |
42 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.39646309 |
43 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.37235323 |
44 | * KLF5_25053715_ChIP-Seq_YYC3_Human | 1.36052407 |
45 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.33556048 |
46 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.32711407 |
47 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.30410084 |
48 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.30009582 |
49 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.29969777 |
50 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.29587429 |
51 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.29587429 |
52 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.28570328 |
53 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.28443132 |
54 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.27120929 |
55 | ATF3_27146783_Chip-Seq_COLON_Human | 1.24523540 |
56 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.24200233 |
57 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.20977025 |
58 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.20811775 |
59 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.20070248 |
60 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.17435334 |
61 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.16706177 |
62 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.14797407 |
63 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.13895612 |
64 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.12448088 |
65 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.12092380 |
66 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.10606593 |
67 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.10503092 |
68 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.10223860 |
69 | * CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.09895030 |
70 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.09352382 |
71 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.09296874 |
72 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.08167107 |
73 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.06841323 |
74 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.06809905 |
75 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.06760742 |
76 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.06760742 |
77 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.05663850 |
78 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.03993323 |
79 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.03667245 |
80 | * GATA1_19941826_ChIP-Seq_K562_Human | 1.03493579 |
81 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.01252840 |
82 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.00568521 |
83 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.00237288 |
84 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.00146041 |
85 | * KDM2B_26808549_Chip-Seq_K562_Human | 0.99505100 |
86 | * GATA2_19941826_ChIP-Seq_K562_Human | 0.99440913 |
87 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.99233680 |
88 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.99117613 |
89 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.98844929 |
90 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.98844929 |
91 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.96811931 |
92 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.96592890 |
93 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.95415097 |
94 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.91785072 |
95 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.91603579 |
96 | * TP63_23658742_ChIP-Seq_EP156T_Human | 0.91414061 |
97 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.91307279 |
98 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.90329365 |
99 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.89196845 |
100 | * EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.88630106 |
101 | * SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.88236796 |
102 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.88107999 |
103 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.87803594 |
104 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.87696243 |
105 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.87402819 |
106 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.86901727 |
107 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.86708039 |
108 | * CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.85674194 |
109 | JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 0.85585131 |
110 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 0.84981099 |
111 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.84488518 |
112 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.84355284 |
113 | * AR_21909140_ChIP-Seq_LNCAP_Human | 0.84003445 |
114 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.82739854 |
115 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.82302554 |
116 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.81195434 |
117 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.80661745 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005360_urolithiasis | 3.46008916 |
2 | MP0010234_abnormal_vibrissa_follicle | 3.16449966 |
3 | MP0001666_abnormal_nutrient_absorption | 3.12965404 |
4 | MP0000537_abnormal_urethra_morphology | 2.91955953 |
5 | MP0000462_abnormal_digestive_system | 2.84808018 |
6 | MP0005409_darkened_coat_color | 2.83704767 |
7 | MP0008438_abnormal_cutaneous_collagen | 2.70277441 |
8 | MP0004272_abnormal_basement_membrane | 2.70115957 |
9 | MP0005257_abnormal_intraocular_pressure | 2.59975883 |
10 | MP0003705_abnormal_hypodermis_morpholog | 2.59288405 |
11 | MP0004264_abnormal_extraembryonic_tissu | 2.53307248 |
12 | MP0005275_abnormal_skin_tensile | 2.44277915 |
13 | MP0006054_spinal_hemorrhage | 2.26042627 |
14 | MP0001958_emphysema | 2.14396827 |
15 | MP0003300_gastrointestinal_ulcer | 2.05560969 |
16 | MP0000678_abnormal_parathyroid_gland | 2.03247839 |
17 | MP0002796_impaired_skin_barrier | 2.02567723 |
18 | MP0003566_abnormal_cell_adhesion | 2.01404733 |
19 | MP0003252_abnormal_bile_duct | 1.91050812 |
20 | MP0009384_cardiac_valve_regurgitation | 1.90728151 |
21 | MP0005085_abnormal_gallbladder_physiolo | 1.88520350 |
22 | MP0003183_abnormal_peptide_metabolism | 1.87748390 |
23 | MP0002139_abnormal_hepatobiliary_system | 1.87241891 |
24 | MP0003283_abnormal_digestive_organ | 1.80777123 |
25 | MP0005503_abnormal_tendon_morphology | 1.76062035 |
26 | MP0003941_abnormal_skin_development | 1.70856613 |
27 | MP0009840_abnormal_foam_cell | 1.70437288 |
28 | MP0010368_abnormal_lymphatic_system | 1.66687200 |
29 | MP0010678_abnormal_skin_adnexa | 1.64512736 |
30 | MP0003868_abnormal_feces_composition | 1.64219527 |
31 | MP0003453_abnormal_keratinocyte_physiol | 1.64178265 |
32 | MP0008875_abnormal_xenobiotic_pharmacok | 1.61857382 |
33 | MP0002295_abnormal_pulmonary_circulatio | 1.58184428 |
34 | MP0005623_abnormal_meninges_morphology | 1.55654370 |
35 | MP0002060_abnormal_skin_morphology | 1.52361215 |
36 | MP0004858_abnormal_nervous_system | 1.51116858 |
37 | MP0001849_ear_inflammation | 1.49666694 |
38 | MP0009643_abnormal_urine_homeostasis | 1.49094544 |
39 | MP0010352_gastrointestinal_tract_polyps | 1.48944281 |
40 | MP0005023_abnormal_wound_healing | 1.47422762 |
41 | MP0003950_abnormal_plasma_membrane | 1.46479289 |
42 | MP0008004_abnormal_stomach_pH | 1.44347403 |
43 | MP0004185_abnormal_adipocyte_glucose | 1.43800757 |
44 | MP0009379_abnormal_foot_pigmentation | 1.43065026 |
45 | MP0002877_abnormal_melanocyte_morpholog | 1.42845608 |
46 | MP0005501_abnormal_skin_physiology | 1.37757659 |
47 | MP0000579_abnormal_nail_morphology | 1.37323676 |
48 | MP0005365_abnormal_bile_salt | 1.35231833 |
49 | MP0005167_abnormal_blood-brain_barrier | 1.34148464 |
50 | MP0003045_fibrosis | 1.33672330 |
51 | MP0004043_abnormal_pH_regulation | 1.31902212 |
52 | MP0001664_abnormal_digestion | 1.29930805 |
53 | MP0005381_digestive/alimentary_phenotyp | 1.27585886 |
54 | MP0004019_abnormal_vitamin_homeostasis | 1.24989920 |
55 | MP0005083_abnormal_biliary_tract | 1.23692499 |
56 | MP0000477_abnormal_intestine_morphology | 1.20782385 |
57 | MP0003866_abnormal_defecation | 1.19806282 |
58 | MP0005332_abnormal_amino_acid | 1.18643987 |
59 | MP0002896_abnormal_bone_mineralization | 1.18413756 |
60 | MP0003091_abnormal_cell_migration | 1.17275878 |
61 | MP0000467_abnormal_esophagus_morphology | 1.14286266 |
62 | MP0001765_abnormal_ion_homeostasis | 1.13399340 |
63 | MP0010030_abnormal_orbit_morphology | 1.12144003 |
64 | MP0004147_increased_porphyrin_level | 1.11209803 |
65 | MP0000534_abnormal_ureter_morphology | 1.10793483 |
66 | MP0005408_hypopigmentation | 1.10058856 |
67 | MP0003806_abnormal_nucleotide_metabolis | 1.09579046 |
68 | MP0001879_abnormal_lymphatic_vessel | 1.07707286 |
69 | MP0000762_abnormal_tongue_morphology | 1.04286790 |
70 | MP0002098_abnormal_vibrissa_morphology | 1.03653599 |
71 | MP0000470_abnormal_stomach_morphology | 1.03458753 |
72 | MP0000003_abnormal_adipose_tissue | 1.02780117 |
73 | MP0002136_abnormal_kidney_physiology | 1.02460360 |
74 | MP0003191_abnormal_cellular_cholesterol | 1.02312539 |
75 | MP0001756_abnormal_urination | 1.00360686 |
76 | MP0003279_aneurysm | 0.96989750 |
77 | MP0000383_abnormal_hair_follicle | 0.96533295 |
78 | MP0001873_stomach_inflammation | 0.96420376 |
79 | MP0004782_abnormal_surfactant_physiolog | 0.95821791 |
80 | MP0010155_abnormal_intestine_physiology | 0.95374153 |
81 | MP0000538_abnormal_urinary_bladder | 0.93666441 |
82 | MP0001663_abnormal_digestive_system | 0.93264274 |
83 | MP0005508_abnormal_skeleton_morphology | 0.91985908 |
84 | MP0005367_renal/urinary_system_phenotyp | 0.91737535 |
85 | MP0000516_abnormal_urinary_system | 0.91737535 |
86 | MP0005076_abnormal_cell_differentiation | 0.91232633 |
87 | MP0000013_abnormal_adipose_tissue | 0.91032157 |
88 | MP0000920_abnormal_myelination | 0.90894440 |
89 | MP0010329_abnormal_lipoprotein_level | 0.90461105 |
90 | MP0001216_abnormal_epidermal_layer | 0.89346373 |
91 | MP0002108_abnormal_muscle_morphology | 0.87455357 |
92 | MP0004947_skin_inflammation | 0.86464416 |
93 | MP0005375_adipose_tissue_phenotype | 0.85021438 |
94 | MP0010771_integument_phenotype | 0.83766944 |
95 | MP0002118_abnormal_lipid_homeostasis | 0.83445966 |
96 | MP0005058_abnormal_lysosome_morphology | 0.83359671 |
97 | MP0002998_abnormal_bone_remodeling | 0.81986027 |
98 | MP0000681_abnormal_thyroid_gland | 0.81355226 |
99 | MP0005165_increased_susceptibility_to | 0.80899442 |
100 | MP0003656_abnormal_erythrocyte_physiolo | 0.79224178 |
101 | MP0001243_abnormal_dermal_layer | 0.78204273 |
102 | MP0000767_abnormal_smooth_muscle | 0.77785819 |
103 | MP0002168_other_aberrant_phenotype | 0.77693003 |
104 | MP0005666_abnormal_adipose_tissue | 0.75473624 |
105 | MP0000230_abnormal_systemic_arterial | 0.74805260 |
106 | MP0000490_abnormal_crypts_of | 0.74785164 |
107 | MP0000566_synostosis | 0.72971077 |
108 | MP0009780_abnormal_chondrocyte_physiolo | 0.72483311 |
109 | MP0001346_abnormal_lacrimal_gland | 0.72214557 |
110 | MP0000163_abnormal_cartilage_morphology | 0.71082574 |
111 | MP0009931_abnormal_skin_appearance | 0.70955331 |
112 | MP0003329_amyloid_beta_deposits | 0.70309023 |
113 | MP0000377_abnormal_hair_follicle | 0.70227973 |
114 | MP0002249_abnormal_larynx_morphology | 0.69379305 |
115 | MP0001542_abnormal_bone_strength | 0.69153750 |
116 | MP0005164_abnormal_response_to | 0.68873443 |
117 | MP0005451_abnormal_body_composition | 0.67060445 |
118 | MP0001881_abnormal_mammary_gland | 0.66734305 |
119 | MP0002089_abnormal_postnatal_growth/wei | 0.66636579 |
120 | MP0005166_decreased_susceptibility_to | 0.66523809 |
121 | MP0003115_abnormal_respiratory_system | 0.66011937 |
122 | MP0000627_abnormal_mammary_gland | 0.65888750 |
123 | MP0005670_abnormal_white_adipose | 0.65505710 |
124 | MP0005636_abnormal_mineral_homeostasis | 0.64894115 |
125 | MP0004084_abnormal_cardiac_muscle | 0.64853425 |
126 | MP0002876_abnormal_thyroid_physiology | 0.62946942 |
127 | MP0005390_skeleton_phenotype | 0.62576407 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ileus (HP:0002595) | 4.60579937 |
2 | Right ventricular cardiomyopathy (HP:0011663) | 4.57824347 |
3 | Focal segmental glomerulosclerosis (HP:0000097) | 4.39614835 |
4 | Atrophic scars (HP:0001075) | 3.85682265 |
5 | Glomerulosclerosis (HP:0000096) | 3.73648675 |
6 | Mesangial abnormality (HP:0001966) | 3.57991612 |
7 | Premature rupture of membranes (HP:0001788) | 3.34684190 |
8 | Broad metatarsal (HP:0001783) | 3.02131637 |
9 | Ulnar bowing (HP:0003031) | 3.02038381 |
10 | Flat acetabular roof (HP:0003180) | 2.92524061 |
11 | Abnormal albumin level (HP:0012116) | 2.92319694 |
12 | Hypoalbuminemia (HP:0003073) | 2.92319694 |
13 | Abnormal tarsal ossification (HP:0008369) | 2.91615268 |
14 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.88172274 |
15 | Malnutrition (HP:0004395) | 2.82215404 |
16 | Fragile skin (HP:0001030) | 2.80477750 |
17 | Hydroxyprolinuria (HP:0003080) | 2.79835202 |
18 | Abnormality of proline metabolism (HP:0010907) | 2.79835202 |
19 | Milia (HP:0001056) | 2.77719875 |
20 | Protrusio acetabuli (HP:0003179) | 2.76624561 |
21 | Hyperactive renin-angiotensin system (HP:0000841) | 2.74977722 |
22 | Spinal cord compression (HP:0002176) | 2.73741990 |
23 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.72171025 |
24 | Aortic aneurysm (HP:0004942) | 2.71711808 |
25 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 2.71582728 |
26 | Aortic dissection (HP:0002647) | 2.64019336 |
27 | Decreased circulating renin level (HP:0003351) | 2.61256888 |
28 | Alopecia of scalp (HP:0002293) | 2.57498868 |
29 | Polycythemia (HP:0001901) | 2.57319640 |
30 | Vertebral compression fractures (HP:0002953) | 2.56790323 |
31 | Abdominal distention (HP:0003270) | 2.54268085 |
32 | Arterial tortuosity (HP:0005116) | 2.48019995 |
33 | Abnormality of chloride homeostasis (HP:0011422) | 2.47495390 |
34 | Coronal craniosynostosis (HP:0004440) | 2.47411103 |
35 | Fragile nails (HP:0001808) | 2.47052584 |
36 | Onycholysis (HP:0001806) | 2.45475956 |
37 | Cardiovascular calcification (HP:0011915) | 2.42275718 |
38 | Turricephaly (HP:0000262) | 2.41918942 |
39 | Abnormality of the acetabulum (HP:0003170) | 2.40769603 |
40 | Pustule (HP:0200039) | 2.39928718 |
41 | Interstitial pulmonary disease (HP:0006530) | 2.35722000 |
42 | Cupped ribs (HP:0000887) | 2.35219059 |
43 | Potter facies (HP:0002009) | 2.32672756 |
44 | Facial shape deformation (HP:0011334) | 2.32672756 |
45 | Vascular calcification (HP:0004934) | 2.32581930 |
46 | Abnormal foot bone ossification (HP:0010675) | 2.32099212 |
47 | Bladder diverticulum (HP:0000015) | 2.32031094 |
48 | Systemic lupus erythematosus (HP:0002725) | 2.31033346 |
49 | Cerebral aneurysm (HP:0004944) | 2.25350210 |
50 | Hemorrhage of the eye (HP:0011885) | 2.24949754 |
51 | Pterygium (HP:0001059) | 2.24257052 |
52 | Ankle contracture (HP:0006466) | 2.24150472 |
53 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.22177019 |
54 | Shallow orbits (HP:0000586) | 2.17532690 |
55 | Nephritis (HP:0000123) | 2.15994576 |
56 | Hyporeflexia of lower limbs (HP:0002600) | 2.15621952 |
57 | Premature skin wrinkling (HP:0100678) | 2.13500496 |
58 | Blue sclerae (HP:0000592) | 2.12855205 |
59 | Metabolic alkalosis (HP:0200114) | 2.12401196 |
60 | Follicular hyperkeratosis (HP:0007502) | 2.07044281 |
61 | Hyperphosphatemia (HP:0002905) | 2.06079806 |
62 | Abnormal hair laboratory examination (HP:0003328) | 2.05529420 |
63 | Rectal prolapse (HP:0002035) | 2.04533375 |
64 | Gastrointestinal dysmotility (HP:0002579) | 2.01933813 |
65 | Thin bony cortex (HP:0002753) | 2.01572970 |
66 | Bowing of the arm (HP:0006488) | 2.01268792 |
67 | Bowed forearm bones (HP:0003956) | 2.01268792 |
68 | Genu recurvatum (HP:0002816) | 2.00056866 |
69 | Upper limb amyotrophy (HP:0009129) | 1.99310933 |
70 | Distal upper limb amyotrophy (HP:0007149) | 1.99310933 |
71 | Coxa vara (HP:0002812) | 1.98988152 |
72 | Abnormality of the 2nd finger (HP:0004100) | 1.98104465 |
73 | Osteoarthritis (HP:0002758) | 1.97629364 |
74 | Increased circulating renin level (HP:0000848) | 1.97603077 |
75 | Dilatation of the ascending aorta (HP:0005111) | 1.97349370 |
76 | Abnormality of renin-angiotensin system (HP:0000847) | 1.97236260 |
77 | Abnormality of complement system (HP:0005339) | 1.96380053 |
78 | Overgrowth (HP:0001548) | 1.94607805 |
79 | Fat malabsorption (HP:0002630) | 1.94522512 |
80 | Advanced eruption of teeth (HP:0006288) | 1.94450012 |
81 | Ovoid vertebral bodies (HP:0003300) | 1.93255255 |
82 | Neonatal short-limb short stature (HP:0008921) | 1.92423955 |
83 | Abnormality of carpal bone ossification (HP:0006257) | 1.91634324 |
84 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.90808255 |
85 | Hypokalemic alkalosis (HP:0001949) | 1.90319814 |
86 | Spinal rigidity (HP:0003306) | 1.89483730 |
87 | Intrahepatic cholestasis (HP:0001406) | 1.89023846 |
88 | Short hallux (HP:0010109) | 1.88928184 |
89 | Deep venous thrombosis (HP:0002625) | 1.88229179 |
90 | Plantar hyperkeratosis (HP:0007556) | 1.87811903 |
91 | Peritonitis (HP:0002586) | 1.87778054 |
92 | Corneal erosion (HP:0200020) | 1.86346417 |
93 | Widely patent fontanelles and sutures (HP:0004492) | 1.85874722 |
94 | Metaphyseal cupping (HP:0003021) | 1.85476237 |
95 | Pili torti (HP:0003777) | 1.85191178 |
96 | Aneurysm (HP:0002617) | 1.85132575 |
97 | Renal salt wasting (HP:0000127) | 1.84921974 |
98 | Hyperextensible skin (HP:0000974) | 1.84752947 |
99 | Cervical subluxation (HP:0003308) | 1.84477489 |
100 | Abnormal ossification of hand bones (HP:0005921) | 1.84164694 |
101 | Esophageal varix (HP:0002040) | 1.83763525 |
102 | Conjugated hyperbilirubinemia (HP:0002908) | 1.83673802 |
103 | Bronchomalacia (HP:0002780) | 1.83214590 |
104 | Visceral angiomatosis (HP:0100761) | 1.82516348 |
105 | Neurofibrillary tangles (HP:0002185) | 1.82396383 |
106 | Stage 5 chronic kidney disease (HP:0003774) | 1.81915002 |
107 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.81304789 |
108 | Soft skin (HP:0000977) | 1.81300982 |
109 | Osteolytic defects of the hand bones (HP:0009699) | 1.80626025 |
110 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.80626025 |
111 | Tibial bowing (HP:0002982) | 1.80547440 |
112 | Stridor (HP:0010307) | 1.80462067 |
113 | Nonimmune hydrops fetalis (HP:0001790) | 1.80089153 |
114 | Femoral bowing (HP:0002980) | 1.79666908 |
115 | Abnormal hemoglobin (HP:0011902) | 1.79081650 |
116 | Natal tooth (HP:0000695) | 1.78948068 |
117 | Muscle fiber splitting (HP:0003555) | 1.77875170 |
118 | Xanthomatosis (HP:0000991) | 1.77440521 |
119 | Woolly hair (HP:0002224) | 1.76984137 |
120 | Hyperaldosteronism (HP:0000859) | 1.76565211 |
121 | Flattened epiphyses (HP:0003071) | 1.76383813 |
122 | Wormian bones (HP:0002645) | 1.75742484 |
123 | Vascular tortuosity (HP:0004948) | 1.75552351 |
124 | Abnormal vertebral ossification (HP:0100569) | 1.75032258 |
125 | Dehydration (HP:0001944) | 1.73800097 |
126 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.73655668 |
127 | Ankyloglossia (HP:0010296) | 1.73067878 |
128 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.72961710 |
129 | Bone pain (HP:0002653) | 1.71829916 |
130 | Increased connective tissue (HP:0009025) | 1.71471985 |
131 | Hyperparathyroidism (HP:0000843) | 1.71356806 |
132 | Dysostosis multiplex (HP:0000943) | 1.71117306 |
133 | Breech presentation (HP:0001623) | 1.70483484 |
134 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.70244379 |
135 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.70244379 |
136 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.70244379 |
137 | Abnormal hand bone ossification (HP:0010660) | 1.69946763 |
138 | Hypotension (HP:0002615) | 1.69930952 |
139 | Diaphragmatic weakness (HP:0009113) | 1.69925710 |
140 | Complement deficiency (HP:0004431) | 1.69411630 |
141 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.68013243 |
142 | Villous atrophy (HP:0011473) | 1.68013243 |
143 | Protuberant abdomen (HP:0001538) | 1.66702593 |
144 | Hemangiomatosis (HP:0007461) | 1.65969622 |
145 | Hypoplasia of dental enamel (HP:0006297) | 1.65725072 |
146 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.65581999 |
147 | Mitral stenosis (HP:0001718) | 1.64471659 |
148 | Mucopolysacchariduria (HP:0008155) | 1.63762562 |
Rank | Gene Set | Z-score |
---|---|---|
1 | STK39 | 3.80645108 |
2 | MST4 | 3.23234367 |
3 | WNK4 | 2.90653092 |
4 | EPHB1 | 2.84858107 |
5 | EPHA2 | 2.78534182 |
6 | DDR2 | 2.66978040 |
7 | OXSR1 | 2.57842263 |
8 | LATS1 | 2.47070142 |
9 | FRK | 2.33449371 |
10 | EPHB2 | 2.32804010 |
11 | MET | 2.27546861 |
12 | MST1R | 2.26026002 |
13 | LMTK2 | 2.19440874 |
14 | EEF2K | 2.05560094 |
15 | RIPK1 | 1.98744274 |
16 | ACVR1B | 1.92116460 |
17 | PTK6 | 1.83552349 |
18 | ERN1 | 1.76484606 |
19 | PRKG2 | 1.75466294 |
20 | MAP2K2 | 1.74715627 |
21 | ICK | 1.72613813 |
22 | PDGFRA | 1.69791340 |
23 | TRIB3 | 1.65741474 |
24 | MYLK | 1.64031660 |
25 | MAPK15 | 1.60742430 |
26 | TIE1 | 1.56490144 |
27 | FER | 1.52090888 |
28 | TRPM7 | 1.50502426 |
29 | BMX | 1.50476769 |
30 | SMG1 | 1.49464315 |
31 | PTK2 | 1.49253427 |
32 | AKT3 | 1.47460289 |
33 | MAP3K2 | 1.47158507 |
34 | PRPF4B | 1.46703660 |
35 | CDK12 | 1.42477883 |
36 | PIK3CA | 1.38323545 |
37 | DMPK | 1.33839136 |
38 | LRRK2 | 1.32336191 |
39 | PAK4 | 1.27286694 |
40 | FGFR2 | 1.22802669 |
41 | STK24 | 1.21971442 |
42 | FGFR3 | 1.20898329 |
43 | NUAK1 | 1.11550587 |
44 | TGFBR2 | 1.11246847 |
45 | MAP3K10 | 1.10738522 |
46 | STK10 | 1.10195020 |
47 | TTN | 1.08139416 |
48 | IRAK3 | 1.07324024 |
49 | PAK2 | 1.03913799 |
50 | TESK1 | 0.99141183 |
51 | NEK9 | 0.96854189 |
52 | MAPKAPK5 | 0.96716022 |
53 | SIK1 | 0.96168047 |
54 | LIMK1 | 0.96050812 |
55 | PDGFRB | 0.93173191 |
56 | PAK3 | 0.91908501 |
57 | SCYL2 | 0.90658495 |
58 | GSK3A | 0.88351276 |
59 | WNK1 | 0.87941532 |
60 | STK38 | 0.86042868 |
61 | NTRK1 | 0.85357818 |
62 | MAP2K1 | 0.85110466 |
63 | TAOK1 | 0.84177550 |
64 | STK3 | 0.82395779 |
65 | RPS6KA2 | 0.80905416 |
66 | MAP3K3 | 0.80900270 |
67 | LATS2 | 0.79235900 |
68 | CSK | 0.77902617 |
69 | MAP3K6 | 0.77006850 |
70 | TAOK3 | 0.76710504 |
71 | TYRO3 | 0.75373442 |
72 | MAP3K7 | 0.74268887 |
73 | DYRK1B | 0.73963947 |
74 | MAP3K11 | 0.73550296 |
75 | KSR2 | 0.73412449 |
76 | PRKD2 | 0.73388933 |
77 | PRKD1 | 0.73153849 |
78 | MATK | 0.72120189 |
79 | MAP3K12 | 0.71977333 |
80 | CAMK2B | 0.70241731 |
81 | KDR | 0.70009869 |
82 | ROCK2 | 0.68756092 |
83 | FGFR4 | 0.66676440 |
84 | EPHA3 | 0.64068469 |
85 | ROCK1 | 0.63945189 |
86 | NME1 | 0.63648565 |
87 | ABL2 | 0.63469863 |
88 | FGR | 0.59942409 |
89 | MAPK11 | 0.59003172 |
90 | MTOR | 0.58809816 |
91 | CAMK2D | 0.58680607 |
92 | ERBB2 | 0.57200930 |
93 | BCR | 0.57159957 |
94 | PDPK1 | 0.56604888 |
95 | TESK2 | 0.56281329 |
96 | TYK2 | 0.55899862 |
97 | STK38L | 0.55871102 |
98 | PTK2B | 0.53561153 |
99 | MAP3K1 | 0.50868334 |
100 | CAMK1D | 0.49569911 |
101 | CDC42BPA | 0.48413667 |
102 | CAMK2G | 0.48306254 |
103 | PIK3CG | 0.47538576 |
104 | PRKAA2 | 0.47423492 |
105 | FGFR1 | 0.47374194 |
106 | JAK1 | 0.45992349 |
107 | PKN2 | 0.43617448 |
108 | PDK2 | 0.41793327 |
109 | NLK | 0.41214786 |
110 | MAP3K8 | 0.40937521 |
111 | MAPK7 | 0.39089286 |
112 | HIPK2 | 0.38469787 |
113 | ERBB4 | 0.38277763 |
114 | ILK | 0.37639696 |
115 | RET | 0.36252347 |
116 | MAPKAPK3 | 0.35908172 |
117 | NEK6 | 0.35784487 |
118 | PAK1 | 0.35203221 |
119 | SGK3 | 0.34453971 |
120 | MARK2 | 0.34353182 |
121 | CSNK1A1L | 0.34187058 |
122 | EGFR | 0.33290027 |
123 | SRC | 0.32854961 |
124 | INSR | 0.32823572 |
125 | PDK1 | 0.32702147 |
126 | PRKD3 | 0.31710182 |
127 | TBK1 | 0.30657787 |
128 | ARAF | 0.30628454 |
129 | MAP2K6 | 0.29893111 |
130 | MAP3K13 | 0.29312282 |
131 | PRKCI | 0.28210243 |
132 | MAPKAPK2 | 0.26092430 |
133 | CDK6 | 0.25569257 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.17335862 |
2 | Fat digestion and absorption_Homo sapiens_hsa04975 | 2.95441132 |
3 | Mineral absorption_Homo sapiens_hsa04978 | 2.78964532 |
4 | Renin-angiotensin system_Homo sapiens_hsa04614 | 2.54934904 |
5 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.50116615 |
6 | Protein digestion and absorption_Homo sapiens_hsa04974 | 2.43456081 |
7 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.01156142 |
8 | Other glycan degradation_Homo sapiens_hsa00511 | 1.88110171 |
9 | Histidine metabolism_Homo sapiens_hsa00340 | 1.85318773 |
10 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.84070921 |
11 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.83262654 |
12 | Tight junction_Homo sapiens_hsa04530 | 1.73440187 |
13 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.72246883 |
14 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.64433193 |
15 | Bile secretion_Homo sapiens_hsa04976 | 1.63066368 |
16 | Adherens junction_Homo sapiens_hsa04520 | 1.53549439 |
17 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.51931039 |
18 | Focal adhesion_Homo sapiens_hsa04510 | 1.50423918 |
19 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.50317800 |
20 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.43663506 |
21 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.40742218 |
22 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.38271409 |
23 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.37304159 |
24 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.31114185 |
25 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.27195372 |
26 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.26895621 |
27 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.25681088 |
28 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.25507747 |
29 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.25147337 |
30 | Bladder cancer_Homo sapiens_hsa05219 | 1.24363675 |
31 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.23933361 |
32 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.21490497 |
33 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.18679112 |
34 | Amoebiasis_Homo sapiens_hsa05146 | 1.15822253 |
35 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.15502568 |
36 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.12254697 |
37 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.10916621 |
38 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.10354341 |
39 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.08220090 |
40 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.06597859 |
41 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.03258995 |
42 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.01892539 |
43 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.01848501 |
44 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.01834035 |
45 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.00549085 |
46 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.98191159 |
47 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.98127147 |
48 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.98003210 |
49 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.97257587 |
50 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.97121894 |
51 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.97058448 |
52 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.95934192 |
53 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.95765662 |
54 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.94779916 |
55 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.94162548 |
56 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.90352477 |
57 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.89177358 |
58 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.88892340 |
59 | Galactose metabolism_Homo sapiens_hsa00052 | 0.88385394 |
60 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.87985471 |
61 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.87674710 |
62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.87616236 |
63 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.84488926 |
64 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.82654002 |
65 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.81350610 |
66 | Thyroid cancer_Homo sapiens_hsa05216 | 0.81073702 |
67 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.80756781 |
68 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.78007517 |
69 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.76959505 |
70 | ABC transporters_Homo sapiens_hsa02010 | 0.76946869 |
71 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.76867379 |
72 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.74412696 |
73 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.74068364 |
74 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.73755115 |
75 | Insulin resistance_Homo sapiens_hsa04931 | 0.73653624 |
76 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.73016084 |
77 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.70836941 |
78 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.69863088 |
79 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.69729831 |
80 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.69294094 |
81 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.66263792 |
82 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.64963553 |
83 | Retinol metabolism_Homo sapiens_hsa00830 | 0.63406750 |
84 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.62666071 |
85 | Axon guidance_Homo sapiens_hsa04360 | 0.59999008 |
86 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.57406182 |
87 | Lysosome_Homo sapiens_hsa04142 | 0.57247735 |
88 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.56523792 |
89 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.55736128 |
90 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.54385601 |
91 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.53690084 |
92 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.52305923 |
93 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.51818942 |
94 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.51477797 |
95 | Prion diseases_Homo sapiens_hsa05020 | 0.51239893 |
96 | Salmonella infection_Homo sapiens_hsa05132 | 0.50861509 |
97 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.50452530 |
98 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.50255751 |
99 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.47515256 |
100 | Endocytosis_Homo sapiens_hsa04144 | 0.47179045 |
101 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.45935452 |
102 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.45554538 |
103 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.44667051 |
104 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.44426024 |
105 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.44264485 |
106 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.43850133 |
107 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.43539177 |
108 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.42941685 |
109 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.42718247 |
110 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.42315084 |
111 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.41284627 |
112 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.40589485 |
113 | Endometrial cancer_Homo sapiens_hsa05213 | 0.40557326 |
114 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.39317492 |
115 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.39217164 |
116 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.38343126 |
117 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.38129342 |
118 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.37968338 |
119 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.37577692 |
120 | Lysine degradation_Homo sapiens_hsa00310 | 0.36910975 |
121 | Renin secretion_Homo sapiens_hsa04924 | 0.36574506 |
122 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.35593853 |
123 | Peroxisome_Homo sapiens_hsa04146 | 0.35112464 |
124 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.34568513 |
125 | Shigellosis_Homo sapiens_hsa05131 | 0.34368099 |
126 | Hepatitis C_Homo sapiens_hsa05160 | 0.33912404 |
127 | Prostate cancer_Homo sapiens_hsa05215 | 0.33487820 |
128 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.32234301 |
129 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.31437075 |
130 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.30697300 |