MYO5B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene, together with other proteins, may be involved in plasma membrane recycling. Mutations in this gene are associated with microvillous inclusion disease. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1desmosome organization (GO:0002934)7.61890630
2drug catabolic process (GO:0042737)5.20527208
3regulation of water loss via skin (GO:0033561)4.89337066
4intestinal epithelial cell development (GO:0060576)4.78510444
5multicellular organismal water homeostasis (GO:0050891)4.74928341
6establishment of skin barrier (GO:0061436)4.60996305
7cysteine metabolic process (GO:0006534)4.55684339
8intestinal absorption (GO:0050892)4.51890991
9epoxygenase P450 pathway (GO:0019373)4.51856446
10drug transmembrane transport (GO:0006855)4.40661605
11lysine metabolic process (GO:0006553)4.39386431
12lysine catabolic process (GO:0006554)4.39386431
13bile acid and bile salt transport (GO:0015721)4.25304729
14negative regulation of keratinocyte proliferation (GO:0010839)4.15680350
15regulation of bile acid biosynthetic process (GO:0070857)4.12338712
16hemidesmosome assembly (GO:0031581)4.10201598
17sulfur amino acid catabolic process (GO:0000098)4.08523090
18intestinal cholesterol absorption (GO:0030299)4.03851919
19exogenous drug catabolic process (GO:0042738)4.02328483
20water homeostasis (GO:0030104)3.97993483
21maintenance of gastrointestinal epithelium (GO:0030277)3.88798354
22homocysteine metabolic process (GO:0050667)3.87712793
23bundle of His cell to Purkinje myocyte communication (GO:0086069)3.85103020
24urate metabolic process (GO:0046415)3.84525784
25flavonoid metabolic process (GO:0009812)3.81385255
26calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.79493678
27kynurenine metabolic process (GO:0070189)3.77942310
28O-glycan processing (GO:0016266)3.76863620
29cellular ketone body metabolic process (GO:0046950)3.75050966
30triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.72608508
31drug transport (GO:0015893)3.70923610
32urea cycle (GO:0000050)3.68102706
33urea metabolic process (GO:0019627)3.68102706
34erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.67607144
35L-phenylalanine catabolic process (GO:0006559)3.67607144
36primary alcohol catabolic process (GO:0034310)3.67380983
37aromatic amino acid family catabolic process (GO:0009074)3.67016017
38tryptophan catabolic process (GO:0006569)3.64072426
39indole-containing compound catabolic process (GO:0042436)3.64072426
40indolalkylamine catabolic process (GO:0046218)3.64072426
41diterpenoid biosynthetic process (GO:0016102)3.62691156
42vitamin transmembrane transport (GO:0035461)3.60647140
43erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.58808148
44L-phenylalanine metabolic process (GO:0006558)3.58808148
45phosphate ion transmembrane transport (GO:0035435)3.48372876
46amino-acid betaine metabolic process (GO:0006577)3.44962837
47phosphate ion transport (GO:0006817)3.42957779
48fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.42888486
49ethanol metabolic process (GO:0006067)3.40144557
50angiotensin maturation (GO:0002003)3.39612722
51epithelial cell-cell adhesion (GO:0090136)3.39473767
52keratinization (GO:0031424)3.37483675
53tryptophan metabolic process (GO:0006568)3.34624447
54nitrogen cycle metabolic process (GO:0071941)3.31782383
55glyoxylate metabolic process (GO:0046487)3.29232951
56regulation of triglyceride catabolic process (GO:0010896)3.26870694
57auditory receptor cell differentiation (GO:0042491)3.24779695
58tight junction assembly (GO:0070830)3.19945071
59gap junction assembly (GO:0016264)3.19815537
60sphingomyelin metabolic process (GO:0006684)3.19527357
61ketone body metabolic process (GO:1902224)3.17631016
62keratinocyte proliferation (GO:0043616)3.17367028
63regulation of cholesterol homeostasis (GO:2000188)3.17314150
64regulation of transforming growth factor beta1 production (GO:0032908)3.16544043
65alpha-linolenic acid metabolic process (GO:0036109)3.13938916
66short-chain fatty acid metabolic process (GO:0046459)3.13896811
67aspartate family amino acid catabolic process (GO:0009068)3.13340256
68glutamate metabolic process (GO:0006536)3.12444436
69negative regulation of cholesterol transport (GO:0032375)3.12142752
70negative regulation of sterol transport (GO:0032372)3.12142752
71transcytosis (GO:0045056)3.12065916
72regulation of keratinocyte differentiation (GO:0045616)3.11071852
73branching involved in mammary gland duct morphogenesis (GO:0060444)3.08873074
74amino-acid betaine transport (GO:0015838)3.08207145
75carnitine transport (GO:0015879)3.08207145
76very-low-density lipoprotein particle assembly (GO:0034379)3.07757948
77renal system process involved in regulation of blood volume (GO:0001977)3.07395974
78regulation of keratinocyte proliferation (GO:0010837)3.05158690
79sulfate transmembrane transport (GO:1902358)3.02545409
80bile acid metabolic process (GO:0008206)3.01700721
81serine family amino acid catabolic process (GO:0009071)2.99851612
82COPII vesicle coating (GO:0048208)2.99220376
83phospholipid efflux (GO:0033700)2.98092423
84high-density lipoprotein particle remodeling (GO:0034375)2.95796387
85NADH metabolic process (GO:0006734)2.95767434
86drug metabolic process (GO:0017144)2.94839409
87phospholipid homeostasis (GO:0055091)2.93841130
88cellular glucuronidation (GO:0052695)2.93126764
89quaternary ammonium group transport (GO:0015697)2.92125032
90ventricular cardiac muscle cell action potential (GO:0086005)2.91258692
91regulation of guanylate cyclase activity (GO:0031282)2.90592044
92positive regulation of epidermal cell differentiation (GO:0045606)2.90356250
93bile acid biosynthetic process (GO:0006699)2.89776701
94hormone catabolic process (GO:0042447)2.89164420
95fat-soluble vitamin biosynthetic process (GO:0042362)2.88758998
96fatty acid beta-oxidation (GO:0006635)2.88108190
97axonemal dynein complex assembly (GO:0070286)2.87947896
98carnitine metabolic process (GO:0009437)2.87652178
99reverse cholesterol transport (GO:0043691)2.86791948
100cellular modified amino acid catabolic process (GO:0042219)2.85758197
101sterol homeostasis (GO:0055092)2.85639380
102fatty acid oxidation (GO:0019395)2.85092343
103cell communication involved in cardiac conduction (GO:0086065)2.83669504
104cholesterol homeostasis (GO:0042632)2.82366898
105pyrimidine-containing compound transmembrane transport (GO:0072531)2.81447415
106positive regulation of glycoprotein biosynthetic process (GO:0010560)2.80111368
107phenylpropanoid metabolic process (GO:0009698)2.79653706
108epithelial structure maintenance (GO:0010669)2.78792753
109sodium ion homeostasis (GO:0055078)2.78428387
110fructose metabolic process (GO:0006000)2.78208876
111lipid oxidation (GO:0034440)2.77972914
112regulation of systemic arterial blood pressure by hormone (GO:0001990)2.77513763
113regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)2.77513763
114endocrine process (GO:0050886)2.77513763
115regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.76059433
116lipoprotein metabolic process (GO:0042157)2.75863141
117cytoskeletal anchoring at plasma membrane (GO:0007016)2.75276312
118surfactant homeostasis (GO:0043129)2.74692864
119digestion (GO:0007586)2.74409861
120regulation of cholesterol esterification (GO:0010872)2.73939017
121positive regulation of glycoprotein metabolic process (GO:1903020)2.73870671
122skin morphogenesis (GO:0043589)2.72104958
123modified amino acid transport (GO:0072337)2.71566240
124macroautophagy (GO:0016236)2.70782029
125COPI coating of Golgi vesicle (GO:0048205)2.70104881
126Golgi transport vesicle coating (GO:0048200)2.70104881
127regulation of cardioblast differentiation (GO:0051890)2.69748435
128organic cation transport (GO:0015695)2.68109500
129cell-cell junction assembly (GO:0007043)2.68026281
1302-oxoglutarate metabolic process (GO:0006103)2.67951332
131benzene-containing compound metabolic process (GO:0042537)2.67722554
132sulfur compound transport (GO:0072348)2.67356509
133carnitine shuttle (GO:0006853)2.66995981
134primary alcohol metabolic process (GO:0034308)2.66213898
135ethanol oxidation (GO:0006069)2.65615084
136fatty acid catabolic process (GO:0009062)2.65449899
137digestive system process (GO:0022600)2.64893509
138acylglycerol homeostasis (GO:0055090)2.64012188
139triglyceride homeostasis (GO:0070328)2.64012188
140glutathione derivative biosynthetic process (GO:1901687)2.62907296
141glutathione derivative metabolic process (GO:1901685)2.62907296
142excretion (GO:0007588)2.62823843
143fatty acid transmembrane transport (GO:1902001)2.61795566
144nucleobase catabolic process (GO:0046113)2.61637199
145cholesterol efflux (GO:0033344)2.61602525
146cellular amino acid catabolic process (GO:0009063)2.61300212
147acetyl-CoA metabolic process (GO:0006084)2.61155084
148positive regulation of lipid catabolic process (GO:0050996)2.60649947
149protein-lipid complex remodeling (GO:0034368)2.60474896
150macromolecular complex remodeling (GO:0034367)2.60474896
151plasma lipoprotein particle remodeling (GO:0034369)2.60474896
152uronic acid metabolic process (GO:0006063)2.58987474
153glucuronate metabolic process (GO:0019585)2.58987474
154lipoprotein transport (GO:0042953)2.58679853
155vitamin transport (GO:0051180)2.58314604
156alpha-amino acid catabolic process (GO:1901606)2.58212842
157keratinocyte differentiation (GO:0030216)2.58157452
158positive regulation of Cdc42 GTPase activity (GO:0043089)2.57880764
159plasma lipoprotein particle assembly (GO:0034377)2.56207221
160receptor recycling (GO:0001881)2.53882719
161columnar/cuboidal epithelial cell development (GO:0002066)2.53454807
162UDP-N-acetylglucosamine metabolic process (GO:0006047)2.53403902
163citrulline biosynthetic process (GO:0019240)2.51668399
164cilium or flagellum-dependent cell motility (GO:0001539)2.50810893
165epidermal cell differentiation (GO:0009913)2.50423344
166glutamine family amino acid biosynthetic process (GO:0009084)2.50315631
167renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)2.48058174
168keratinocyte development (GO:0003334)2.47493991
169regulation of transforming growth factor beta2 production (GO:0032909)2.47409922
170nucleotide-sugar biosynthetic process (GO:0009226)2.47142459
171oligosaccharide biosynthetic process (GO:0009312)2.46829057

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.66267934
2RXR_22158963_ChIP-Seq_LIVER_Mouse3.59468264
3SMAD4_19686287_ChIP-ChIP_HaCaT_Human3.42342273
4LXR_22158963_ChIP-Seq_LIVER_Mouse3.22394990
5PPARA_22158963_ChIP-Seq_LIVER_Mouse3.18487977
6NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.35808750
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.18088252
8EGR1_23403033_ChIP-Seq_LIVER_Mouse2.17189761
9KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human2.06209733
10TRIM28_21343339_ChIP-Seq_HEK293_Human2.04653494
11FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.03066018
12* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.91520142
13* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.91520142
14CDX2_20551321_ChIP-Seq_CACO-2_Human1.87947604
15CDX2_19796622_ChIP-Seq_MESCs_Mouse1.85534147
16* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.84030779
17KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.82489395
18HIF1A_21447827_ChIP-Seq_MCF-7_Human1.79952729
19ESR2_21235772_ChIP-Seq_MCF-7_Human1.78824678
20FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.78768175
21AR_21909140_ChIP-Seq_LNCAP_Human1.77509466
22ESR1_20079471_ChIP-ChIP_T-47D_Human1.76869707
23P63_26484246_Chip-Seq_KERATINOCYTES_Human1.74546159
24STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.71197723
25ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.67570385
26EZH2_22144423_ChIP-Seq_EOC_Human1.66106356
27ZNF217_24962896_ChIP-Seq_MCF-7_Human1.62522426
28* FOXA2_19822575_ChIP-Seq_HepG2_Human1.56006562
29TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.55087718
30GATA4_25053715_ChIP-Seq_YYC3_Human1.49188629
31TP63_17297297_ChIP-ChIP_HaCaT_Human1.48198965
32ESR1_21235772_ChIP-Seq_MCF-7_Human1.46383293
33ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.43330877
34GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39614005
35SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.39161476
36FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.38729670
37HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.37769453
38TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.37182879
39PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.35431032
40PPAR_26484153_Chip-Seq_NCI-H1993_Human1.34576605
41FOXO3_23340844_ChIP-Seq_DLD1_Human1.33829413
42ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.32694084
43GATA6_25053715_ChIP-Seq_YYC3_Human1.31407758
44EP300_21415370_ChIP-Seq_HL-1_Mouse1.28273868
45* SOX2_20726797_ChIP-Seq_SW620_Human1.27326046
46RARG_19884340_ChIP-ChIP_MEFs_Mouse1.25944217
47RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.25734997
48TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.23975697
49ATF3_27146783_Chip-Seq_COLON_Human1.22206308
50CJUN_26792858_Chip-Seq_BT549_Human1.18893748
51* HNF4A_19822575_ChIP-Seq_HepG2_Human1.17737381
52ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.17687744
53TCF4_18268006_ChIP-ChIP_LS174T_Human1.16608254
54DROSHA_22980978_ChIP-Seq_HELA_Human1.16121833
55BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.15372130
56RUNX1_27514584_Chip-Seq_MCF-7_Human1.13606278
57* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.12690179
58FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.12563097
59ZNF263_19887448_ChIP-Seq_K562_Human1.11747605
60AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11709937
61FOXM1_26456572_ChIP-Seq_MCF-7_Human1.11495922
62AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.11387740
63* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.10383428
64* SMAD3_21741376_ChIP-Seq_HESCs_Human1.10238353
65AHR_22903824_ChIP-Seq_MCF-7_Human1.07309745
66MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.04291850
67TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.04247160
68BCAT_22108803_ChIP-Seq_LS180_Human1.03568697
69CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.02339305
70ESR1_15608294_ChIP-ChIP_MCF-7_Human1.01962386
71PIAS1_25552417_ChIP-Seq_VCAP_Human1.01392446
72CLOCK_20551151_ChIP-Seq_293T_Human1.01220057
73* SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.00915475
74* CDX2_22108803_ChIP-Seq_LS180_Human1.00601708
75* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.98525360
76ARNT_22903824_ChIP-Seq_MCF-7_Human0.97833634
77NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.97517221
78EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96536023
79CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.95780188
80* ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.93971851
81TP53_18474530_ChIP-ChIP_U2OS_Human0.91385794
82* SMAD4_21741376_ChIP-Seq_HESCs_Human0.91381273
83KAP1_22055183_ChIP-Seq_ESCs_Mouse0.91298936
84RARB_27405468_Chip-Seq_BRAIN_Mouse0.90906766
85TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.90022691
86SALL4_18804426_ChIP-ChIP_XEN_Mouse0.89952048
87EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.89735119
88STAT6_21828071_ChIP-Seq_BEAS2B_Human0.89264668
89TP63_22573176_ChIP-Seq_HFKS_Human0.88589215
90PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.88092647
91GATA2_21666600_ChIP-Seq_HMVEC_Human0.87854261
92SMAD4_21799915_ChIP-Seq_A2780_Human0.87610247
93RXR_22108803_ChIP-Seq_LS180_Human0.87010351
94TP63_23658742_ChIP-Seq_EP156T_Human0.86980883
95* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.86329935
96SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.86111354
97CREB1_26743006_Chip-Seq_LNCaP_Human0.85981563
98SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.85844450
99* EZH2_18974828_ChIP-Seq_MESCs_Mouse0.85775640
100* RNF2_18974828_ChIP-Seq_MESCs_Mouse0.85775640
101PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.85513361
102KLF5_25053715_ChIP-Seq_YYC3_Human0.85449620
103* SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.85300761
104VDR_22108803_ChIP-Seq_LS180_Human0.85109059
105CTNNB1_20460455_ChIP-Seq_HCT116_Human0.82312755
106* EZH2_27294783_Chip-Seq_ESCs_Mouse0.82114485
107CHD1_26751641_Chip-Seq_LNCaP_Human0.81743602
108ERG_21242973_ChIP-ChIP_JURKAT_Human0.81641661
109* NR3C1_23031785_ChIP-Seq_PC12_Mouse0.81472840
110EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.80630174
111PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.80104256
112P300_27058665_Chip-Seq_ZR-75-30cells_Human0.78816039
113* SUZ12_27294783_Chip-Seq_ESCs_Mouse0.78568913
114CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.78352146
115NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.78043266
116NRF2_20460467_ChIP-Seq_MEFs_Mouse0.78043266
117* CTCF_27219007_Chip-Seq_Bcells_Human0.77871478
118FOXA1_25552417_ChIP-Seq_VCAP_Human0.77786371
119TBX20_22328084_ChIP-Seq_HEART_Mouse0.77745073
120TBX20_22080862_ChIP-Seq_HEART_Mouse0.77745073
121KDM2B_26808549_Chip-Seq_K562_Human0.77328637
122SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.77294682
123GBX2_23144817_ChIP-Seq_PC3_Human0.76769795
124AR_25329375_ChIP-Seq_VCAP_Human0.76069625
125JARID2_20075857_ChIP-Seq_MESCs_Mouse0.75640758
126CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.75449204
127GATA3_24758297_ChIP-Seq_MCF-7_Human0.75403001
128FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.75379710
129NFIB_24661679_ChIP-Seq_LUNG_Mouse0.74692520
130FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.74640805
131STAT3_23295773_ChIP-Seq_U87_Human0.74410657
132TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.74129479
133* RACK7_27058665_Chip-Seq_MCF-7_Human0.74003530
134SOX2_21211035_ChIP-Seq_LN229_Gbm0.72998354
135SMAD4_21741376_ChIP-Seq_EPCs_Human0.72180689
136SOX9_24532713_ChIP-Seq_HFSC_Mouse0.72063658
137STAT1_17558387_ChIP-Seq_HELA_Human0.71761225
138Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.70785706
139ELF5_23300383_ChIP-Seq_T47D_Human0.69025786

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis7.07269006
2MP0002139_abnormal_hepatobiliary_system5.61558596
3MP0005085_abnormal_gallbladder_physiolo4.63300003
4MP0008875_abnormal_xenobiotic_pharmacok4.34670390
5MP0010234_abnormal_vibrissa_follicle4.26225996
6MP0005365_abnormal_bile_salt3.86313137
7MP0001666_abnormal_nutrient_absorption3.46410038
8MP0003252_abnormal_bile_duct3.37035578
9MP0002822_catalepsy3.06512348
10MP0010352_gastrointestinal_tract_polyps2.98285152
11MP0004019_abnormal_vitamin_homeostasis2.51037666
12MP0010329_abnormal_lipoprotein_level2.46846366
13MP0000566_synostosis2.42285693
14MP0002098_abnormal_vibrissa_morphology2.42191505
15MP0004264_abnormal_extraembryonic_tissu2.40303453
16MP0004043_abnormal_pH_regulation2.33119403
17MP0005332_abnormal_amino_acid2.30098561
18MP0005501_abnormal_skin_physiology2.24440849
19MP0003941_abnormal_skin_development2.23261559
20MP0000383_abnormal_hair_follicle2.17762165
21MP0002138_abnormal_hepatobiliary_system2.13650101
22MP0003183_abnormal_peptide_metabolism2.07268929
23MP0005409_darkened_coat_color2.07150418
24MP0005377_hearing/vestibular/ear_phenot2.04642969
25MP0003878_abnormal_ear_physiology2.04642969
26MP0005451_abnormal_body_composition1.95043103
27MP0003453_abnormal_keratinocyte_physiol1.88132179
28MP0001765_abnormal_ion_homeostasis1.87123592
29MP0009840_abnormal_foam_cell1.79952163
30MP0000678_abnormal_parathyroid_gland1.78823693
31MP0004859_abnormal_synaptic_plasticity1.71292638
32MP0009643_abnormal_urine_homeostasis1.69672694
33MP0001216_abnormal_epidermal_layer1.69298801
34MP0003191_abnormal_cellular_cholesterol1.67223872
35MP0003806_abnormal_nucleotide_metabolis1.58286852
36MP0002118_abnormal_lipid_homeostasis1.51057061
37MP0003195_calcinosis1.50785821
38MP0000377_abnormal_hair_follicle1.49859662
39MP0009780_abnormal_chondrocyte_physiolo1.47305193
40MP0000467_abnormal_esophagus_morphology1.43154448
41MP0000462_abnormal_digestive_system1.43124238
42MP0000762_abnormal_tongue_morphology1.42549044
43MP0005636_abnormal_mineral_homeostasis1.38564618
44MP0002060_abnormal_skin_morphology1.38410704
45MP0003646_muscle_fatigue1.34306153
46MP0003566_abnormal_cell_adhesion1.34177168
47MP0005275_abnormal_skin_tensile1.33435920
48MP0003718_maternal_effect1.32607354
49MP0005167_abnormal_blood-brain_barrier1.29439858
50MP0001756_abnormal_urination1.26098003
51MP0003329_amyloid_beta_deposits1.25088590
52MP0002796_impaired_skin_barrier1.24670196
53MP0010155_abnormal_intestine_physiology1.24504417
54MP0010771_integument_phenotype1.24293907
55MP0005076_abnormal_cell_differentiation1.22457041
56MP0002837_dystrophic_cardiac_calcinosis1.21505156
57MP0003868_abnormal_feces_composition1.20771566
58MP0003705_abnormal_hypodermis_morpholog1.20182477
59MP0004270_analgesia1.18223075
60MP0009379_abnormal_foot_pigmentation1.17947653
61MP0000609_abnormal_liver_physiology1.16037023
62MP0003879_abnormal_hair_cell1.16019619
63MP0005084_abnormal_gallbladder_morpholo1.14716463
64MP0001664_abnormal_digestion1.14358943
65MP0005319_abnormal_enzyme/_coenzyme1.14346549
66MP0000627_abnormal_mammary_gland1.13066249
67MP0005023_abnormal_wound_healing1.12721964
68MP0003300_gastrointestinal_ulcer1.06542728
69MP0005083_abnormal_biliary_tract1.06143850
70MP0000427_abnormal_hair_cycle1.02892369
71MP0005584_abnormal_enzyme/coenzyme_acti0.99282823
72MP0000538_abnormal_urinary_bladder0.98438586
73MP0001881_abnormal_mammary_gland0.97830113
74MP0002896_abnormal_bone_mineralization0.97234071
75MP0010678_abnormal_skin_adnexa0.97028149
76MP0002136_abnormal_kidney_physiology0.95415854
77MP0004885_abnormal_endolymph0.93501685
78MP0004185_abnormal_adipocyte_glucose0.90419294
79MP0001663_abnormal_digestive_system0.90224744
80MP0005381_digestive/alimentary_phenotyp0.90142822
81MP0004782_abnormal_surfactant_physiolog0.90103726
82MP0008961_abnormal_basal_metabolism0.87804511
83MP0008872_abnormal_physiological_respon0.87010478
84MP0000604_amyloidosis0.83988542
85MP0005395_other_phenotype0.83938886
86MP0002876_abnormal_thyroid_physiology0.82910757
87MP0000579_abnormal_nail_morphology0.81589136
88MP0004272_abnormal_basement_membrane0.81231399
89MP0005367_renal/urinary_system_phenotyp0.80851787
90MP0000516_abnormal_urinary_system0.80851787
91MP0001873_stomach_inflammation0.78354386
92MP0004130_abnormal_muscle_cell0.78294635
93MP0003866_abnormal_defecation0.77361093
94MP0004484_altered_response_of0.76572105
95MP0005187_abnormal_penis_morphology0.76362486
96MP0000537_abnormal_urethra_morphology0.76227051
97MP0009384_cardiac_valve_regurgitation0.76059873
98MP0003950_abnormal_plasma_membrane0.74461058
99MP0000230_abnormal_systemic_arterial0.72916145
100MP0002909_abnormal_adrenal_gland0.72880610
101MP0005666_abnormal_adipose_tissue0.71451806
102MP0005257_abnormal_intraocular_pressure0.70223249
103MP0005166_decreased_susceptibility_to0.68700884
104MP0001849_ear_inflammation0.68490242
105MP0005670_abnormal_white_adipose0.68306666
106MP0009931_abnormal_skin_appearance0.67196868
107MP0002254_reproductive_system_inflammat0.66173560
108MP0002063_abnormal_learning/memory/cond0.65113172
109MP0000470_abnormal_stomach_morphology0.64517807
110MP0000465_gastrointestinal_hemorrhage0.64458261
111MP0002168_other_aberrant_phenotype0.63300092
112MP0000367_abnormal_coat/_hair0.62842667
113MP0008004_abnormal_stomach_pH0.62165579
114MP0001440_abnormal_grooming_behavior0.61985909
115MP0000003_abnormal_adipose_tissue0.61755544
116MP0002166_altered_tumor_susceptibility0.61653601
117MP0004947_skin_inflammation0.61478053
118MP0003635_abnormal_synaptic_transmissio0.60787798
119MP0000490_abnormal_crypts_of0.60548182
120MP0005248_abnormal_Harderian_gland0.60075750
121MP0002078_abnormal_glucose_homeostasis0.59593952
122MP0010368_abnormal_lymphatic_system0.58893248
123MP0002295_abnormal_pulmonary_circulatio0.58459646
124MP0003699_abnormal_female_reproductive0.58234211
125MP0003936_abnormal_reproductive_system0.56829779
126MP0009642_abnormal_blood_homeostasis0.56740340
127MP0001177_atelectasis0.56261465
128MP0002234_abnormal_pharynx_morphology0.56215907
129MP0005535_abnormal_body_temperature0.56122608
130MP0004215_abnormal_myocardial_fiber0.55430423
131MP0003890_abnormal_embryonic-extraembry0.55236937
132MP0005058_abnormal_lysosome_morphology0.53787431
133MP0005647_abnormal_sex_gland0.53465718
134MP0005408_hypopigmentation0.52789370
135MP0006138_congestive_heart_failure0.52633721
136MP0000477_abnormal_intestine_morphology0.51616954
137MP0003943_abnormal_hepatobiliary_system0.51539669
138MP0001764_abnormal_homeostasis0.51207049
139MP0003953_abnormal_hormone_level0.51094801
140MP0005410_abnormal_fertilization0.50368214
141MP0004147_increased_porphyrin_level0.49921229
142MP0005375_adipose_tissue_phenotype0.49473785
143MP0005448_abnormal_energy_balance0.49117486
144MP0004858_abnormal_nervous_system0.48640891
145MP0002971_abnormal_brown_adipose0.46945283

Predicted human phenotypes

RankGene SetZ-score
1Hyperactive renin-angiotensin system (HP:0000841)4.82758485
2Gout (HP:0001997)4.77911949
3Abnormality of glutamine family amino acid metabolism (HP:0010902)4.76895983
4Intrahepatic cholestasis (HP:0001406)4.54668656
5Right ventricular cardiomyopathy (HP:0011663)4.52077097
6Hyperglycinuria (HP:0003108)4.08802781
7Pili torti (HP:0003777)4.01534129
8Xanthomatosis (HP:0000991)3.95385102
9Deep venous thrombosis (HP:0002625)3.94657284
10Abnormality of purine metabolism (HP:0004352)3.88591391
11Hypobetalipoproteinemia (HP:0003563)3.78176141
12Hyperuricemia (HP:0002149)3.76072617
13Increased purine levels (HP:0004368)3.76072617
14Abnormality of monocarboxylic acid metabolism (HP:0010996)3.74752509
15Abnormality of chloride homeostasis (HP:0011422)3.71220474
16Decreased circulating renin level (HP:0003351)3.51807606
17Ileus (HP:0002595)3.47757842
18Abnormality of glycine metabolism (HP:0010895)3.41412650
19Abnormality of serine family amino acid metabolism (HP:0010894)3.41412650
20Metabolic alkalosis (HP:0200114)3.36512284
21Proximal tubulopathy (HP:0000114)3.31519839
22Ketoacidosis (HP:0001993)3.31416785
23Ketosis (HP:0001946)3.28292165
24Hyperammonemia (HP:0001987)3.24612989
25Plantar hyperkeratosis (HP:0007556)3.22220696
26Hypolipoproteinemia (HP:0010981)3.21402816
27Facial shape deformation (HP:0011334)3.21013325
28Potter facies (HP:0002009)3.21013325
29Lip pit (HP:0100267)3.20788713
30Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.14534070
31Abnormal hair laboratory examination (HP:0003328)3.11985953
32Abnormality of aromatic amino acid family metabolism (HP:0004338)3.11584657
33Abnormality of nail color (HP:0100643)3.08880548
34Fat malabsorption (HP:0002630)3.08414938
35Conjugated hyperbilirubinemia (HP:0002908)3.07321612
36Palmoplantar hyperkeratosis (HP:0000972)2.99858794
37Increased circulating renin level (HP:0000848)2.93883645
38Abnormality of proline metabolism (HP:0010907)2.89617166
39Hydroxyprolinuria (HP:0003080)2.89617166
40Hypoalphalipoproteinemia (HP:0003233)2.89469367
41Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.88945748
42Abnormality of nucleobase metabolism (HP:0010932)2.88909115
43Abnormality of aspartate family amino acid metabolism (HP:0010899)2.87765261
44Alopecia of scalp (HP:0002293)2.86181538
45Hyperkalemia (HP:0002153)2.81779156
46Palmar hyperkeratosis (HP:0010765)2.80166010
47Hypoglycemic coma (HP:0001325)2.79283569
48Acanthocytosis (HP:0001927)2.78934802
49Hyperglycinemia (HP:0002154)2.75225098
50Cholecystitis (HP:0001082)2.74522581
51Abnormal gallbladder physiology (HP:0012438)2.74522581
52Abnormality of fatty-acid metabolism (HP:0004359)2.74392374
53Male infertility (HP:0003251)2.73990486
54Hyperlipoproteinemia (HP:0010980)2.72472293
55Abnormality of sulfur amino acid metabolism (HP:0004339)2.71084945
56Alkalosis (HP:0001948)2.69584228
57Epidermoid cyst (HP:0200040)2.66779313
58Curly hair (HP:0002212)2.64259254
59Steatorrhea (HP:0002570)2.61612772
60Rhinitis (HP:0012384)2.61030998
61Hypokalemic alkalosis (HP:0001949)2.60939331
62Abnormality of renin-angiotensin system (HP:0000847)2.60641226
63Hyperaldosteronism (HP:0000859)2.59968826
64Abnormality of the gastric mucosa (HP:0004295)2.57256236
65Abnormality of renal excretion (HP:0011036)2.57001409
66Popliteal pterygium (HP:0009756)2.54606807
67Widely patent fontanelles and sutures (HP:0004492)2.53346523
68Metabolic acidosis (HP:0001942)2.48001968
69Hypercholesterolemia (HP:0003124)2.47618314
70Sensorimotor neuropathy (HP:0007141)2.46938624
71Milia (HP:0001056)2.46271757
72Abnormal respiratory motile cilium physiology (HP:0012261)2.45187942
73Syncope (HP:0001279)2.44975402
74Abnormality of urine glucose concentration (HP:0011016)2.44578270
75Glycosuria (HP:0003076)2.44578270
76Abnormal tarsal ossification (HP:0008369)2.43084391
77Abnormal urine output (HP:0012590)2.41564314
78Vascular calcification (HP:0004934)2.40985271
79Woolly hair (HP:0002224)2.40866838
80Onycholysis (HP:0001806)2.38444754
81Focal segmental glomerulosclerosis (HP:0000097)2.37683993
82Hyponatremia (HP:0002902)2.35618527
83* Malnutrition (HP:0004395)2.34841322
84Thin bony cortex (HP:0002753)2.34517483
85Glomerulosclerosis (HP:0000096)2.32996291
86Ventricular fibrillation (HP:0001663)2.32088250
87* Dehydration (HP:0001944)2.30507807
88Abnormal ciliary motility (HP:0012262)2.30176386
89Hyperglycemia (HP:0003074)2.26319121
90Hypoplasia of dental enamel (HP:0006297)2.25207353
91Confusion (HP:0001289)2.25202110
92Nephrolithiasis (HP:0000787)2.24982893
93Abnormality of carpal bone ossification (HP:0006257)2.24810172
94Generalized aminoaciduria (HP:0002909)2.23122479
95Complement deficiency (HP:0004431)2.20154537
96Bronchiectasis (HP:0002110)2.17125954
97Flat acetabular roof (HP:0003180)2.13830728
98Delayed CNS myelination (HP:0002188)2.13288619
99Tubulointerstitial fibrosis (HP:0005576)2.12282946
100Abnormal respiratory motile cilium morphology (HP:0005938)2.11999182
101Abnormal respiratory epithelium morphology (HP:0012253)2.11999182
102Abnormality of the distal phalanx of the thumb (HP:0009617)2.11950547
103Bundle branch block (HP:0011710)2.09554494
104Cardiovascular calcification (HP:0011915)2.09423284
105Abnormality of the distal phalanges of the toes (HP:0010182)2.08793174
106Abdominal distention (HP:0003270)2.07802547
107Hypotension (HP:0002615)2.06070004
108Dicarboxylic aciduria (HP:0003215)2.05528234
109Abnormality of dicarboxylic acid metabolism (HP:0010995)2.05528234
110Abnormal biliary tract morphology (HP:0012440)2.04714879
111Hyperphosphatemia (HP:0002905)2.04093695
112Germ cell neoplasia (HP:0100728)2.03804189
113Dynein arm defect of respiratory motile cilia (HP:0012255)2.02099923
114Absent/shortened dynein arms (HP:0200106)2.02099923
115Late onset (HP:0003584)1.99605042
116Hypotrichosis (HP:0001006)1.98946463
117Hyperparathyroidism (HP:0000843)1.97369699
118Fragile nails (HP:0001808)1.96506526
119Spontaneous abortion (HP:0005268)1.96014192
120Tetany (HP:0001281)1.94383225
121Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.94296544
122Renal tubular acidosis (HP:0001947)1.94199849
123Esophageal varix (HP:0002040)1.92447927
124Abnormality of the nasal septum (HP:0000419)1.91381891
125Advanced eruption of teeth (HP:0006288)1.91188565
126Polyuria (HP:0000103)1.91176209
127Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.90208849
128Congenital ichthyosiform erythroderma (HP:0007431)1.90057839
129Irritability (HP:0000737)1.89842119
130Abnormal hand bone ossification (HP:0010660)1.89223010
131Shawl scrotum (HP:0000049)1.89062959
132Cerebral inclusion bodies (HP:0100314)1.88853444
133Abnormality of permanent molar morphology (HP:0011071)1.88610910
134Abnormality of the dental root (HP:0006486)1.88610910
135Taurodontia (HP:0000679)1.88610910
136Hypomagnesemia (HP:0002917)1.87886422
137Chronic bronchitis (HP:0004469)1.87435014
138Chronic diarrhea (HP:0002028)1.87181556
139Renal salt wasting (HP:0000127)1.85170011
140Hemorrhage of the eye (HP:0011885)1.84652586
141Hypoplastic labia majora (HP:0000059)1.84544136
142Rickets (HP:0002748)1.84012918
143Lethargy (HP:0001254)1.83717821
144Nasal polyposis (HP:0100582)1.83694083
145Palpitations (HP:0001962)1.83434702
146Abnormality of potassium homeostasis (HP:0011042)1.82836895
147Abnormal pancreas size (HP:0012094)1.82521495
148Atrophic scars (HP:0001075)1.82321125
149Glomerulonephritis (HP:0000099)1.82187572
150Prolonged partial thromboplastin time (HP:0003645)1.81157426
151Polycythemia (HP:0001901)1.80734368
152Ventricular arrhythmia (HP:0004308)1.80696502
153Abnormality of sodium homeostasis (HP:0010931)1.79508701
154Hepatocellular carcinoma (HP:0001402)1.78800598
155Abnormality of vitamin metabolism (HP:0100508)1.78353879
156Pterygium (HP:0001059)1.78050585
157Ventricular tachycardia (HP:0004756)1.78027188
158Abnormality of the dental pulp (HP:0006479)1.76209953
159Abnormality of the common coagulation pathway (HP:0010990)1.75668143
160Pigmentary retinal degeneration (HP:0001146)1.75178626
161Subcapsular cataract (HP:0000523)1.74569769
162Abnormality of molar morphology (HP:0011070)1.72027816
163Abnormality of molar (HP:0011077)1.72027816

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST1R5.11815604
2KSR24.03210738
3MAP3K23.27379913
4PIK3CA3.04125908
5LMTK22.77307013
6FRK2.62588157
7MAP3K92.61480770
8EPHA42.55824832
9ACVR1B2.54187779
10LATS12.41909495
11TAOK32.40712990
12WNK42.16796338
13MAP3K121.99732944
14STK38L1.81773650
15PRKD31.73335656
16CDK121.70484580
17PDK41.67801898
18PDK31.67801898
19MET1.66735339
20NME11.65706824
21TAOK11.65532699
22OXSR11.60685667
23LATS21.56989897
24WNK31.54470530
25MAP3K61.38652180
26MAPK151.35957156
27SIK11.35100929
28STK381.32784619
29MAP2K11.31713663
30MAP2K21.29647661
31MAP3K41.28962852
32ERBB41.26754213
33EPHA21.25167371
34RIPK11.24733299
35MAP3K31.22035018
36PBK1.21222895
37MAP3K11.20466689
38MAP2K41.16764443
39RET1.10758423
40FER1.09907025
41MAP3K131.09513891
42DMPK1.08588873
43KSR11.07992663
44STK391.06789542
45NTRK31.06299689
46BCR1.04694490
47NEK61.03930636
48PDK21.00762044
49DAPK21.00038921
50FGFR30.99358317
51BCKDK0.97998306
52TTK0.96799090
53TRIB30.93403877
54ICK0.92827365
55PAK40.92188273
56ARAF0.91550383
57CASK0.89820906
58MST40.89818752
59PTK2B0.88497540
60SMG10.88087219
61EIF2AK30.87490746
62EEF2K0.87405076
63RAF10.83639430
64MAP3K70.83185556
65MYLK0.82592544
66AKT30.82009041
67PAK30.80694028
68EPHB20.80225154
69TYRO30.79123312
70TRPM70.78127412
71PTK20.73756706
72PDPK10.73241417
73PRKAA20.72699827
74EPHB10.72374928
75PAK60.72227674
76BRAF0.72218057
77NEK10.71935341
78TESK10.71552065
79MAPKAPK30.71516222
80PRKG20.69531355
81PINK10.69369406
82MAP3K100.68111705
83PRKAA10.67811092
84SCYL20.65869557
85PTK60.65532775
86RPS6KB20.65405636
87NLK0.64931365
88RIPK40.64851839
89PDGFRA0.64361054
90SGK30.62115993
91ERBB30.61747956
92BMPR20.61143632
93GRK60.60406267
94FGFR40.59650258
95NUAK10.59082596
96MTOR0.58839091
97EPHA30.56345496
98MINK10.56004605
99LRRK20.55662800
100PKN20.54556501
101ERN10.54265411
102PDK10.54103070
103SGK2230.53969820
104SGK4940.53969820
105PDGFRB0.52523948
106ERBB20.51881834
107CAMK2D0.51716583
108MAP3K80.50561940
109MOS0.50191150
110NTRK10.49542197
111MAPK110.48904661
112CAMK2A0.46995935
113IRAK30.46879536
114CAMKK10.45776895
115CDK90.45526240
116CHUK0.44837498
117MELK0.44684854
118SGK20.43630660
119STK30.43140251
120INSRR0.42219144
121PRKCZ0.42213988
122FGFR10.41789943
123MAP2K70.40633573
124CDK50.40152162
125ABL20.37071832
126YES10.36564625
127MUSK0.35463228
128BMX0.35271758
129WNK10.34887207
130TNIK0.33849751
131SGK10.33600726
132CDC42BPA0.33578546
133CAMK1G0.33023016
134PRKCI0.32887415
135STK110.32660298
136BRD40.32431251
137STK240.31342360
138RPS6KB10.30772304
139FGFR20.26557982
140ROCK10.25584313
141AKT20.25180235
142SIK30.24191552
143CSNK1E0.23940814
144MAP2K60.23893093
145ILK0.21375264
146SRC0.21167491
147IRAK10.21111142

Predicted pathways (KEGG)

RankGene SetZ-score
1Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.98395837
2Nitrogen metabolism_Homo sapiens_hsa009102.69906531
3Bile secretion_Homo sapiens_hsa049762.40574582
4Mineral absorption_Homo sapiens_hsa049782.26482916
5Arginine biosynthesis_Homo sapiens_hsa002202.23080481
6Fatty acid degradation_Homo sapiens_hsa000712.18341864
7Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.15909185
8Fat digestion and absorption_Homo sapiens_hsa049752.14727950
9Tryptophan metabolism_Homo sapiens_hsa003802.12299184
10Primary bile acid biosynthesis_Homo sapiens_hsa001202.12238408
11Sulfur metabolism_Homo sapiens_hsa009202.10431351
12Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.10398907
13Butanoate metabolism_Homo sapiens_hsa006502.10111705
14Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.91534067
15Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.84575458
16Propanoate metabolism_Homo sapiens_hsa006401.83490610
17Pentose and glucuronate interconversions_Homo sapiens_hsa000401.75880702
18PPAR signaling pathway_Homo sapiens_hsa033201.74397778
192-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.65190312
20Vitamin digestion and absorption_Homo sapiens_hsa049771.63753534
21Pyruvate metabolism_Homo sapiens_hsa006201.57582161
22Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.52433511
23Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.51448965
24Caffeine metabolism_Homo sapiens_hsa002321.49578779
25Starch and sucrose metabolism_Homo sapiens_hsa005001.47399568
26Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.46625028
27Histidine metabolism_Homo sapiens_hsa003401.45527850
28Fatty acid metabolism_Homo sapiens_hsa012121.41236551
29Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.40701460
30Sphingolipid metabolism_Homo sapiens_hsa006001.39009769
31Glycerolipid metabolism_Homo sapiens_hsa005611.31914101
32beta-Alanine metabolism_Homo sapiens_hsa004101.31093908
33Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.30725810
34Peroxisome_Homo sapiens_hsa041461.28506509
35Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.25512912
36Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.22845433
37Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.20046243
38Renin-angiotensin system_Homo sapiens_hsa046141.17587851
39Chemical carcinogenesis_Homo sapiens_hsa052041.17311129
40Cyanoamino acid metabolism_Homo sapiens_hsa004601.16869060
41Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.15630116
42Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.13478274
43Carbohydrate digestion and absorption_Homo sapiens_hsa049731.05030136
44Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.03599254
45Carbon metabolism_Homo sapiens_hsa012001.03584110
46Maturity onset diabetes of the young_Homo sapiens_hsa049501.02404411
47Arachidonic acid metabolism_Homo sapiens_hsa005901.01859856
48Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.01541127
49Steroid hormone biosynthesis_Homo sapiens_hsa001400.97439209
50ABC transporters_Homo sapiens_hsa020100.92553272
51Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.91162788
52Salivary secretion_Homo sapiens_hsa049700.88842395
53Retinol metabolism_Homo sapiens_hsa008300.87440145
54Protein digestion and absorption_Homo sapiens_hsa049740.85475603
55Glutathione metabolism_Homo sapiens_hsa004800.85228104
56Complement and coagulation cascades_Homo sapiens_hsa046100.83612042
57Gastric acid secretion_Homo sapiens_hsa049710.81563804
58Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.80096765
59Folate biosynthesis_Homo sapiens_hsa007900.78435803
60Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.77437730
61Galactose metabolism_Homo sapiens_hsa000520.77405138
62Cysteine and methionine metabolism_Homo sapiens_hsa002700.74115178
63Arginine and proline metabolism_Homo sapiens_hsa003300.73082296
64Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.71952289
65Biosynthesis of amino acids_Homo sapiens_hsa012300.69412957
66Fructose and mannose metabolism_Homo sapiens_hsa000510.67952111
67Dorso-ventral axis formation_Homo sapiens_hsa043200.66964705
68Phenylalanine metabolism_Homo sapiens_hsa003600.66307782
69Ether lipid metabolism_Homo sapiens_hsa005650.65947415
70Thyroid hormone synthesis_Homo sapiens_hsa049180.65899442
71Lysine degradation_Homo sapiens_hsa003100.64426535
72Selenocompound metabolism_Homo sapiens_hsa004500.63657190
73Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.62084938
74Drug metabolism - other enzymes_Homo sapiens_hsa009830.60675594
75Glycerophospholipid metabolism_Homo sapiens_hsa005640.59321735
76Ovarian steroidogenesis_Homo sapiens_hsa049130.57966655
77Fatty acid biosynthesis_Homo sapiens_hsa000610.57176221
78Circadian rhythm_Homo sapiens_hsa047100.57122906
79Long-term potentiation_Homo sapiens_hsa047200.56764101
80alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.55692202
81Vibrio cholerae infection_Homo sapiens_hsa051100.53370005
82Pancreatic secretion_Homo sapiens_hsa049720.53178012
83Tight junction_Homo sapiens_hsa045300.52947742
84Hepatitis C_Homo sapiens_hsa051600.52274856
85GnRH signaling pathway_Homo sapiens_hsa049120.51684068
86Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.51520415
87Endometrial cancer_Homo sapiens_hsa052130.50303629
88Type II diabetes mellitus_Homo sapiens_hsa049300.49383328
89Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.48919531
90Other glycan degradation_Homo sapiens_hsa005110.47686362
91Renin secretion_Homo sapiens_hsa049240.47070921
92Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.44014896
93Insulin secretion_Homo sapiens_hsa049110.43741062
94Tyrosine metabolism_Homo sapiens_hsa003500.43688776
95Aldosterone synthesis and secretion_Homo sapiens_hsa049250.42980990
96ECM-receptor interaction_Homo sapiens_hsa045120.42749773
97Bladder cancer_Homo sapiens_hsa052190.41369152
98TGF-beta signaling pathway_Homo sapiens_hsa043500.41251196
99Inositol phosphate metabolism_Homo sapiens_hsa005620.39330716
100Glucagon signaling pathway_Homo sapiens_hsa049220.38408477
101Choline metabolism in cancer_Homo sapiens_hsa052310.38404376
102Amphetamine addiction_Homo sapiens_hsa050310.38057167
103Leukocyte transendothelial migration_Homo sapiens_hsa046700.36681537
104Adherens junction_Homo sapiens_hsa045200.34750410
105Circadian entrainment_Homo sapiens_hsa047130.33365804
106Olfactory transduction_Homo sapiens_hsa047400.33220846
107Glutamatergic synapse_Homo sapiens_hsa047240.32207624
108Phosphatidylinositol signaling system_Homo sapiens_hsa040700.31815725
109Hippo signaling pathway_Homo sapiens_hsa043900.31447448
110Amoebiasis_Homo sapiens_hsa051460.31154323
111N-Glycan biosynthesis_Homo sapiens_hsa005100.31035191
112Vitamin B6 metabolism_Homo sapiens_hsa007500.30367093
113Insulin resistance_Homo sapiens_hsa049310.30129273
114Pentose phosphate pathway_Homo sapiens_hsa000300.29995399
115AMPK signaling pathway_Homo sapiens_hsa041520.29554934
116Thyroid cancer_Homo sapiens_hsa052160.28986823
117Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.28639128
118cGMP-PKG signaling pathway_Homo sapiens_hsa040220.27363118
119Vascular smooth muscle contraction_Homo sapiens_hsa042700.26730043
120Gap junction_Homo sapiens_hsa045400.25622531
121Linoleic acid metabolism_Homo sapiens_hsa005910.25227179
122Synaptic vesicle cycle_Homo sapiens_hsa047210.25054723
123Metabolic pathways_Homo sapiens_hsa011000.23945092
124Insulin signaling pathway_Homo sapiens_hsa049100.21666694
125Prostate cancer_Homo sapiens_hsa052150.20113367
126Proteoglycans in cancer_Homo sapiens_hsa052050.19979761
127Steroid biosynthesis_Homo sapiens_hsa001000.18506282
128Thyroid hormone signaling pathway_Homo sapiens_hsa049190.18437675
129ErbB signaling pathway_Homo sapiens_hsa040120.16222695

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »