

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of interferon-beta biosynthetic process (GO:0045357) | 7.59439341 |
| 2 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 7.44273959 |
| 3 | cellular response to zinc ion (GO:0071294) | 6.59937553 |
| 4 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 6.57309067 |
| 5 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 6.55000963 |
| 6 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 6.55000963 |
| 7 | hydrogen peroxide biosynthetic process (GO:0050665) | 6.51946076 |
| 8 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 5.95943595 |
| 9 | positive regulation of macrophage cytokine production (GO:0060907) | 5.77425212 |
| 10 | reactive oxygen species biosynthetic process (GO:1903409) | 5.71773915 |
| 11 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 5.49659222 |
| 12 | regulation of germinal center formation (GO:0002634) | 5.42003663 |
| 13 | B cell receptor signaling pathway (GO:0050853) | 5.10228152 |
| 14 | neutrophil activation involved in immune response (GO:0002283) | 4.79742647 |
| 15 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 4.78641517 |
| 16 | respiratory burst (GO:0045730) | 4.77909265 |
| 17 | DNA damage response, detection of DNA damage (GO:0042769) | 4.60098530 |
| 18 | I-kappaB phosphorylation (GO:0007252) | 4.58955018 |
| 19 | positive regulation of interferon-alpha production (GO:0032727) | 4.54924390 |
| 20 | positive regulation of protein kinase C signaling (GO:0090037) | 4.48220433 |
| 21 | superoxide anion generation (GO:0042554) | 4.44340154 |
| 22 | regulation of macrophage cytokine production (GO:0010935) | 4.40156119 |
| 23 | regulation of hippo signaling (GO:0035330) | 4.30564535 |
| 24 | dermatan sulfate metabolic process (GO:0030205) | 4.19159399 |
| 25 | negative regulation of cAMP-mediated signaling (GO:0043951) | 4.14956797 |
| 26 | poly(A)+ mRNA export from nucleus (GO:0016973) | 4.11997416 |
| 27 | regulation of interferon-alpha production (GO:0032647) | 4.10222912 |
| 28 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 4.08780578 |
| 29 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 4.06534786 |
| 30 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 4.00773252 |
| 31 | regulation of hexokinase activity (GO:1903299) | 3.94917731 |
| 32 | regulation of glucokinase activity (GO:0033131) | 3.94917731 |
| 33 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.93203288 |
| 34 | protein homotrimerization (GO:0070207) | 3.86107182 |
| 35 | activation of Rac GTPase activity (GO:0032863) | 3.82291360 |
| 36 | prepulse inhibition (GO:0060134) | 3.80143883 |
| 37 | cellular response to cadmium ion (GO:0071276) | 3.70878373 |
| 38 | short-term memory (GO:0007614) | 3.59074956 |
| 39 | iron ion import (GO:0097286) | 3.58225843 |
| 40 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.57896301 |
| 41 | regulation of metalloenzyme activity (GO:0048552) | 3.55587536 |
| 42 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 3.54499652 |
| 43 | acrosome reaction (GO:0007340) | 3.52237549 |
| 44 | regulation of mast cell degranulation (GO:0043304) | 3.48310868 |
| 45 | positive regulation of interferon-beta production (GO:0032728) | 3.46669318 |
| 46 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 3.41007073 |
| 47 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 3.41007073 |
| 48 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.36480704 |
| 49 | regulation of antigen processing and presentation (GO:0002577) | 3.32746200 |
| 50 | chondroitin sulfate catabolic process (GO:0030207) | 3.24610078 |
| 51 | regulation of interferon-beta production (GO:0032648) | 3.23080038 |
| 52 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.22597930 |
| 53 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.22246185 |
| 54 | long term synaptic depression (GO:0060292) | 3.15104254 |
| 55 | cellular response to heat (GO:0034605) | 3.09852695 |
| 56 | import into cell (GO:0098657) | 3.07052086 |
| 57 | regulation of RNA export from nucleus (GO:0046831) | 3.03547222 |
| 58 | negative regulation of telomere maintenance (GO:0032205) | 3.02740740 |
| 59 | axonemal dynein complex assembly (GO:0070286) | 3.02568154 |
| 60 | lysosome organization (GO:0007040) | 2.97290146 |
| 61 | lytic vacuole organization (GO:0080171) | 2.97290146 |
| 62 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 2.96658680 |
| 63 | positive regulation of antigen processing and presentation (GO:0002579) | 2.90901622 |
| 64 | positive regulation of chemokine production (GO:0032722) | 2.87692396 |
| 65 | binding of sperm to zona pellucida (GO:0007339) | 2.86373426 |
| 66 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.85535498 |
| 67 | negative regulation of B cell apoptotic process (GO:0002903) | 2.85310349 |
| 68 | neutrophil activation (GO:0042119) | 2.85059736 |
| 69 | positive regulation of interferon-gamma production (GO:0032729) | 2.84787216 |
| 70 | regulation of cilium movement (GO:0003352) | 2.83002978 |
| 71 | positive regulation of T cell apoptotic process (GO:0070234) | 2.82623895 |
| 72 | regulation of Cdc42 GTPase activity (GO:0043088) | 2.79501642 |
| 73 | epithelial structure maintenance (GO:0010669) | 2.79232502 |
| 74 | leukocyte mediated cytotoxicity (GO:0001909) | 2.77699003 |
| 75 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.72476109 |
| 76 | granulocyte activation (GO:0036230) | 2.71973587 |
| 77 | dopamine transport (GO:0015872) | 2.69845733 |
| 78 | biotin metabolic process (GO:0006768) | 2.69318003 |
| 79 | retinal cone cell development (GO:0046549) | 2.68640893 |
| 80 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.67496346 |
| 81 | positive regulation of mast cell degranulation (GO:0043306) | 2.67496346 |
| 82 | type I interferon signaling pathway (GO:0060337) | 2.66629447 |
| 83 | cellular response to type I interferon (GO:0071357) | 2.66629447 |
| 84 | cranial suture morphogenesis (GO:0060363) | 2.66185721 |
| 85 | positive regulation of DNA recombination (GO:0045911) | 2.66048302 |
| 86 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 2.66034410 |
| 87 | response to type I interferon (GO:0034340) | 2.65335970 |
| 88 | positive regulation of histone deacetylation (GO:0031065) | 2.65139776 |
| 89 | positive regulation of CREB transcription factor activity (GO:0032793) | 2.63026299 |
| 90 | ether lipid metabolic process (GO:0046485) | 2.62545582 |
| 91 | myeloid cell activation involved in immune response (GO:0002275) | 2.61086388 |
| 92 | macrophage activation involved in immune response (GO:0002281) | 2.60149834 |
| 93 | short-chain fatty acid metabolic process (GO:0046459) | 2.59831928 |
| 94 | sperm-egg recognition (GO:0035036) | 2.59604372 |
| 95 | prostaglandin biosynthetic process (GO:0001516) | 2.55022969 |
| 96 | prostanoid biosynthetic process (GO:0046457) | 2.55022969 |
| 97 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.54641639 |
| 98 | detection of bacterium (GO:0016045) | 2.54330588 |
| 99 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.53485249 |
| 100 | epithelial cilium movement (GO:0003351) | 2.52329612 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.64147933 |
| 2 | MYC_22102868_ChIP-Seq_BL_Human | 4.30986757 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 4.27899883 |
| 4 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 4.01288846 |
| 5 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 3.75405568 |
| 6 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 3.64377150 |
| 7 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.80426917 |
| 8 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.71009599 |
| 9 | SPI1_23127762_ChIP-Seq_K562_Human | 2.65042742 |
| 10 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.55895989 |
| 11 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 2.46112577 |
| 12 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.44338726 |
| 13 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.31798587 |
| 14 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.22256695 |
| 15 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 2.20919624 |
| 16 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.01583824 |
| 17 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.95255985 |
| 18 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.82988970 |
| 19 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.73609151 |
| 20 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.72516191 |
| 21 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.70822705 |
| 22 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.70377578 |
| 23 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.60130080 |
| 24 | UTX_26944678_Chip-Seq_JUKART_Human | 1.58958573 |
| 25 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.56866492 |
| 26 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.55899428 |
| 27 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.52991452 |
| 28 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.51857201 |
| 29 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.49181333 |
| 30 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.47407752 |
| 31 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.45997039 |
| 32 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.43500825 |
| 33 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.42333602 |
| 34 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.40534176 |
| 35 | MAF_26560356_Chip-Seq_TH1_Human | 1.40165571 |
| 36 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.33633242 |
| 37 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.29973374 |
| 38 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.29424912 |
| 39 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.28649733 |
| 40 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.27972721 |
| 41 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.27759776 |
| 42 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.27509004 |
| 43 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.26359678 |
| 44 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.26199448 |
| 45 | MYB_26560356_Chip-Seq_TH2_Human | 1.25626702 |
| 46 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.24597335 |
| 47 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.24554994 |
| 48 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.23972669 |
| 49 | P68_20966046_ChIP-Seq_HELA_Human | 1.22506460 |
| 50 | P300_27268052_Chip-Seq_Bcells_Human | 1.21795656 |
| 51 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20726717 |
| 52 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.17900806 |
| 53 | MYB_26560356_Chip-Seq_TH1_Human | 1.17084245 |
| 54 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.15253194 |
| 55 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.13981076 |
| 56 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.12842662 |
| 57 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.12401591 |
| 58 | SOX11_22085726_ChIP-Seq_ESNs_Mouse | 1.11366765 |
| 59 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.10582855 |
| 60 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.10367503 |
| 61 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 1.09696952 |
| 62 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.07141851 |
| 63 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.06197033 |
| 64 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.06121789 |
| 65 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.05917603 |
| 66 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.05748312 |
| 67 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.05609227 |
| 68 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.05090559 |
| 69 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.04559588 |
| 70 | MAF_26560356_Chip-Seq_TH2_Human | 1.03044390 |
| 71 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00958623 |
| 72 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.98890254 |
| 73 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.98876836 |
| 74 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.98656030 |
| 75 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.97760625 |
| 76 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.97447734 |
| 77 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.96055503 |
| 78 | GATA3_26560356_Chip-Seq_TH1_Human | 0.95988520 |
| 79 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.94388935 |
| 80 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.94386073 |
| 81 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.93872696 |
| 82 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.93715102 |
| 83 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.92616732 |
| 84 | BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human | 0.92168984 |
| 85 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.92108771 |
| 86 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.90446851 |
| 87 | FLI1_21867929_ChIP-Seq_CD8_Mouse | 0.89918875 |
| 88 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.89790464 |
| 89 | JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 0.88117001 |
| 90 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.87169626 |
| 91 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.85512496 |
| 92 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.85509833 |
| 93 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.85307825 |
| 94 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.85222041 |
| 95 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.84800454 |
| 96 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.84451196 |
| 97 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.84198755 |
| 98 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.84150632 |
| 99 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.83534738 |
| 100 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.82076108 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003880_abnormal_central_pattern | 4.95561343 |
| 2 | MP0003950_abnormal_plasma_membrane | 4.24834722 |
| 3 | MP0003172_abnormal_lysosome_physiology | 3.74304674 |
| 4 | MP0009379_abnormal_foot_pigmentation | 3.54895601 |
| 5 | MP0003191_abnormal_cellular_cholesterol | 3.11136237 |
| 6 | MP0001800_abnormal_humoral_immune | 2.66578665 |
| 7 | MP0001502_abnormal_circadian_rhythm | 2.65186744 |
| 8 | MP0005174_abnormal_tail_pigmentation | 2.63449993 |
| 9 | MP0004043_abnormal_pH_regulation | 2.61184858 |
| 10 | MP0001879_abnormal_lymphatic_vessel | 2.44924313 |
| 11 | MP0008004_abnormal_stomach_pH | 2.44388530 |
| 12 | MP0005387_immune_system_phenotype | 2.44117461 |
| 13 | MP0001790_abnormal_immune_system | 2.44117461 |
| 14 | MP0009384_cardiac_valve_regurgitation | 2.42512674 |
| 15 | MP0005410_abnormal_fertilization | 2.25480618 |
| 16 | MP0005645_abnormal_hypothalamus_physiol | 2.16523764 |
| 17 | MP0003186_abnormal_redox_activity | 2.07671956 |
| 18 | MP0006292_abnormal_olfactory_placode | 2.04163875 |
| 19 | MP0003279_aneurysm | 2.03850904 |
| 20 | MP0002234_abnormal_pharynx_morphology | 2.00975431 |
| 21 | MP0003878_abnormal_ear_physiology | 1.96291053 |
| 22 | MP0005377_hearing/vestibular/ear_phenot | 1.96291053 |
| 23 | MP0004084_abnormal_cardiac_muscle | 1.94414550 |
| 24 | MP0002452_abnormal_antigen_presenting | 1.92488836 |
| 25 | MP0003787_abnormal_imprinting | 1.87350065 |
| 26 | MP0004742_abnormal_vestibular_system | 1.85496931 |
| 27 | MP0006138_congestive_heart_failure | 1.84569390 |
| 28 | MP0001986_abnormal_taste_sensitivity | 1.80886566 |
| 29 | MP0002295_abnormal_pulmonary_circulatio | 1.78396162 |
| 30 | MP0002723_abnormal_immune_serum | 1.75109541 |
| 31 | MP0003879_abnormal_hair_cell | 1.71939898 |
| 32 | MP0001299_abnormal_eye_distance/ | 1.67370870 |
| 33 | MP0004147_increased_porphyrin_level | 1.65401952 |
| 34 | MP0002420_abnormal_adaptive_immunity | 1.63370725 |
| 35 | MP0001819_abnormal_immune_cell | 1.61207311 |
| 36 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.53968268 |
| 37 | MP0000689_abnormal_spleen_morphology | 1.35961687 |
| 38 | MP0004142_abnormal_muscle_tone | 1.31862519 |
| 39 | MP0006276_abnormal_autonomic_nervous | 1.31803607 |
| 40 | MP0005166_decreased_susceptibility_to | 1.31436561 |
| 41 | MP0002398_abnormal_bone_marrow | 1.30507512 |
| 42 | MP0003656_abnormal_erythrocyte_physiolo | 1.30177961 |
| 43 | MP0005025_abnormal_response_to | 1.28630639 |
| 44 | MP0001835_abnormal_antigen_presentation | 1.28258070 |
| 45 | MP0002638_abnormal_pupillary_reflex | 1.25302528 |
| 46 | MP0003436_decreased_susceptibility_to | 1.25023961 |
| 47 | MP0004510_myositis | 1.18767304 |
| 48 | MP0003690_abnormal_glial_cell | 1.16582244 |
| 49 | MP0003221_abnormal_cardiomyocyte_apopto | 1.15816887 |
| 50 | MP0000015_abnormal_ear_pigmentation | 1.15328051 |
| 51 | MP0000343_altered_response_to | 1.12701779 |
| 52 | MP0006035_abnormal_mitochondrial_morpho | 1.12131401 |
| 53 | MP0005058_abnormal_lysosome_morphology | 1.11655351 |
| 54 | MP0003763_abnormal_thymus_physiology | 1.09585122 |
| 55 | MP0005671_abnormal_response_to | 1.02490955 |
| 56 | MP0000538_abnormal_urinary_bladder | 1.02446660 |
| 57 | MP0001764_abnormal_homeostasis | 1.00928920 |
| 58 | MP0000716_abnormal_immune_system | 1.00814205 |
| 59 | MP0000733_abnormal_muscle_development | 0.98542727 |
| 60 | MP0009697_abnormal_copulation | 0.96959737 |
| 61 | MP0002419_abnormal_innate_immunity | 0.95080554 |
| 62 | MP0001849_ear_inflammation | 0.91876641 |
| 63 | MP0002722_abnormal_immune_system | 0.90357041 |
| 64 | MP0003300_gastrointestinal_ulcer | 0.88007887 |
| 65 | MP0002177_abnormal_outer_ear | 0.85795408 |
| 66 | MP0001905_abnormal_dopamine_level | 0.83816155 |
| 67 | MP0001501_abnormal_sleep_pattern | 0.83664379 |
| 68 | MP0000747_muscle_weakness | 0.83516227 |
| 69 | MP0005551_abnormal_eye_electrophysiolog | 0.80950400 |
| 70 | MP0002405_respiratory_system_inflammati | 0.80516779 |
| 71 | MP0005310_abnormal_salivary_gland | 0.80002224 |
| 72 | MP0001968_abnormal_touch/_nociception | 0.79535549 |
| 73 | MP0005023_abnormal_wound_healing | 0.79474484 |
| 74 | MP0002429_abnormal_blood_cell | 0.79037552 |
| 75 | MP0002063_abnormal_learning/memory/cond | 0.78871914 |
| 76 | MP0009785_altered_susceptibility_to | 0.78620510 |
| 77 | MP0003075_altered_response_to | 0.76550216 |
| 78 | MP0003183_abnormal_peptide_metabolism | 0.72553834 |
| 79 | MP0004036_abnormal_muscle_relaxation | 0.71316725 |
| 80 | MP0001845_abnormal_inflammatory_respons | 0.70760532 |
| 81 | MP0008874_decreased_physiological_sensi | 0.70685252 |
| 82 | MP0002095_abnormal_skin_pigmentation | 0.66854172 |
| 83 | MP0009053_abnormal_anal_canal | 0.66007644 |
| 84 | MP0002067_abnormal_sensory_capabilities | 0.65576501 |
| 85 | MP0009703_decreased_birth_body | 0.65528729 |
| 86 | MP0004859_abnormal_synaptic_plasticity | 0.65471041 |
| 87 | MP0004484_altered_response_of | 0.64424481 |
| 88 | MP0002229_neurodegeneration | 0.62645130 |
| 89 | MP0003303_peritoneal_inflammation | 0.62610398 |
| 90 | MP0009745_abnormal_behavioral_response | 0.60386747 |
| 91 | MP0001188_hyperpigmentation | 0.59945416 |
| 92 | MP0002572_abnormal_emotion/affect_behav | 0.59315655 |
| 93 | MP0003828_pulmonary_edema | 0.58622791 |
| 94 | MP0005452_abnormal_adipose_tissue | 0.55554728 |
| 95 | MP0000230_abnormal_systemic_arterial | 0.55520559 |
| 96 | MP0005451_abnormal_body_composition | 0.54758717 |
| 97 | MP0001756_abnormal_urination | 0.54627232 |
| 98 | MP0001486_abnormal_startle_reflex | 0.52128071 |
| 99 | MP0008469_abnormal_protein_level | 0.50416352 |
| 100 | MP0010329_abnormal_lipoprotein_level | 0.50380709 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Agammaglobulinemia (HP:0004432) | 9.21507054 |
| 2 | Cervical subluxation (HP:0003308) | 7.80156195 |
| 3 | Cellulitis (HP:0100658) | 5.85214695 |
| 4 | Recurrent pneumonia (HP:0006532) | 5.80965266 |
| 5 | Eczematoid dermatitis (HP:0000976) | 5.42255309 |
| 6 | Chronic sinusitis (HP:0011109) | 5.13482814 |
| 7 | Recurrent bronchitis (HP:0002837) | 5.12631616 |
| 8 | Broad face (HP:0000283) | 4.62505746 |
| 9 | Hyperglycinemia (HP:0002154) | 4.36925024 |
| 10 | Recurrent lower respiratory tract infections (HP:0002783) | 4.35587804 |
| 11 | Meningitis (HP:0001287) | 4.10613534 |
| 12 | Osteomyelitis (HP:0002754) | 4.09145160 |
| 13 | J-shaped sella turcica (HP:0002680) | 4.07198541 |
| 14 | Papilloma (HP:0012740) | 3.97296153 |
| 15 | Verrucae (HP:0200043) | 3.97296153 |
| 16 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.97211538 |
| 17 | Obstructive sleep apnea (HP:0002870) | 3.73311626 |
| 18 | Mediastinal lymphadenopathy (HP:0100721) | 3.65174063 |
| 19 | Flared iliac wings (HP:0002869) | 3.62505057 |
| 20 | Papilledema (HP:0001085) | 3.48907365 |
| 21 | Bronchitis (HP:0012387) | 3.41314913 |
| 22 | Hypoplasia of the odontoid process (HP:0003311) | 3.40594818 |
| 23 | Chronic obstructive pulmonary disease (HP:0006510) | 3.32331928 |
| 24 | Obstructive lung disease (HP:0006536) | 3.32331928 |
| 25 | Recurrent bacterial skin infections (HP:0005406) | 3.11660211 |
| 26 | Recurrent fungal infections (HP:0002841) | 3.04294676 |
| 27 | Sepsis (HP:0100806) | 3.02886747 |
| 28 | Abnormality of macrophages (HP:0004311) | 2.92651388 |
| 29 | Deformed sella turcica (HP:0002681) | 2.89802943 |
| 30 | Renal cortical cysts (HP:0000803) | 2.79182709 |
| 31 | Abnormality of the odontoid process (HP:0003310) | 2.77265293 |
| 32 | Recurrent otitis media (HP:0000403) | 2.68830563 |
| 33 | Gastrointestinal stroma tumor (HP:0100723) | 2.67855301 |
| 34 | Limb hypertonia (HP:0002509) | 2.65939863 |
| 35 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.63555805 |
| 36 | Abnormality of alanine metabolism (HP:0010916) | 2.63555805 |
| 37 | Hyperalaninemia (HP:0003348) | 2.63555805 |
| 38 | Dehydration (HP:0001944) | 2.60930489 |
| 39 | Recurrent abscess formation (HP:0002722) | 2.59174593 |
| 40 | Inflammation of the large intestine (HP:0002037) | 2.58442144 |
| 41 | Nephronophthisis (HP:0000090) | 2.57415477 |
| 42 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.55446946 |
| 43 | Mucopolysacchariduria (HP:0008155) | 2.55446946 |
| 44 | Colitis (HP:0002583) | 2.46038786 |
| 45 | Hypoplastic labia majora (HP:0000059) | 2.44371770 |
| 46 | Progressive microcephaly (HP:0000253) | 2.42092347 |
| 47 | Sleep apnea (HP:0010535) | 2.41889785 |
| 48 | Recurrent sinusitis (HP:0011108) | 2.40152959 |
| 49 | Biconcave vertebral bodies (HP:0004586) | 2.39157632 |
| 50 | Gastrointestinal inflammation (HP:0004386) | 2.39077779 |
| 51 | Skin rash (HP:0000988) | 2.37752705 |
| 52 | Neurodegeneration (HP:0002180) | 2.36892100 |
| 53 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.36659056 |
| 54 | Increased serum ferritin (HP:0003281) | 2.35589071 |
| 55 | Lymphopenia (HP:0001888) | 2.34125471 |
| 56 | Abnormality of glycine metabolism (HP:0010895) | 2.29666639 |
| 57 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.29666639 |
| 58 | Thrombocytosis (HP:0001894) | 2.28560811 |
| 59 | Restrictive lung disease (HP:0002091) | 2.26130144 |
| 60 | Abnormality of the labia majora (HP:0012881) | 2.24760488 |
| 61 | Abnormality of the sella turcica (HP:0002679) | 2.24679913 |
| 62 | Asplenia (HP:0001746) | 2.24269703 |
| 63 | Abnormality of iron homeostasis (HP:0011031) | 2.23664350 |
| 64 | Hepatosplenomegaly (HP:0001433) | 2.22712915 |
| 65 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.22617327 |
| 66 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.22617327 |
| 67 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.22617327 |
| 68 | Cerebral palsy (HP:0100021) | 2.16146916 |
| 69 | Abnormality of the renal medulla (HP:0100957) | 2.11108683 |
| 70 | Small hand (HP:0200055) | 2.11028867 |
| 71 | Oligodactyly (HP:0012165) | 2.08066516 |
| 72 | Encephalitis (HP:0002383) | 2.06815019 |
| 73 | Hemorrhage of the eye (HP:0011885) | 2.06762289 |
| 74 | Trigonocephaly (HP:0000243) | 2.02757010 |
| 75 | Long palpebral fissure (HP:0000637) | 1.99358541 |
| 76 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.98847505 |
| 77 | Abnormality of the renal cortex (HP:0011035) | 1.96763891 |
| 78 | Panhypogammaglobulinemia (HP:0003139) | 1.96348712 |
| 79 | Growth hormone deficiency (HP:0000824) | 1.94482078 |
| 80 | Oligodactyly (hands) (HP:0001180) | 1.94142714 |
| 81 | Gingivitis (HP:0000230) | 1.93322084 |
| 82 | Microvesicular hepatic steatosis (HP:0001414) | 1.93210199 |
| 83 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.90722340 |
| 84 | Spinal canal stenosis (HP:0003416) | 1.89851042 |
| 85 | Diplopia (HP:0000651) | 1.84757860 |
| 86 | Abnormality of binocular vision (HP:0011514) | 1.84757860 |
| 87 | Labial hypoplasia (HP:0000066) | 1.84726804 |
| 88 | Renal duplication (HP:0000075) | 1.84594768 |
| 89 | Myoglobinuria (HP:0002913) | 1.83764969 |
| 90 | Neutropenia (HP:0001875) | 1.83207691 |
| 91 | 3-Methylglutaconic aciduria (HP:0003535) | 1.83165524 |
| 92 | Hypoplastic female external genitalia (HP:0012815) | 1.81171582 |
| 93 | Recurrent skin infections (HP:0001581) | 1.79302638 |
| 94 | Skin ulcer (HP:0200042) | 1.79103337 |
| 95 | Lymphoma (HP:0002665) | 1.79054969 |
| 96 | Severe visual impairment (HP:0001141) | 1.76506117 |
| 97 | Dysostosis multiplex (HP:0000943) | 1.74663089 |
| 98 | Recurrent viral infections (HP:0004429) | 1.74280813 |
| 99 | Abnormality of serum amino acid levels (HP:0003112) | 1.73043728 |
| 100 | Aortic regurgitation (HP:0001659) | 1.69647649 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ARAF | 5.05083552 |
| 2 | MAP3K13 | 4.44030630 |
| 3 | MAP3K3 | 4.35692147 |
| 4 | DDR2 | 3.03378264 |
| 5 | IRAK4 | 2.83169042 |
| 6 | BMPR2 | 2.66007293 |
| 7 | PKN1 | 2.63600331 |
| 8 | MAP3K6 | 2.23986031 |
| 9 | BLK | 2.13728129 |
| 10 | MAP2K7 | 2.05845887 |
| 11 | MAPK15 | 2.04638612 |
| 12 | MAPK13 | 1.96916842 |
| 13 | KDR | 1.94130813 |
| 14 | NTRK2 | 1.93811569 |
| 15 | TLK1 | 1.88482515 |
| 16 | ILK | 1.85226923 |
| 17 | TYK2 | 1.83445591 |
| 18 | GRK6 | 1.79722136 |
| 19 | KIT | 1.77889451 |
| 20 | EPHA4 | 1.76472056 |
| 21 | MAP3K5 | 1.75526756 |
| 22 | FRK | 1.60638342 |
| 23 | PIM2 | 1.58213242 |
| 24 | TAOK2 | 1.48485996 |
| 25 | NTRK1 | 1.45953714 |
| 26 | PRKD2 | 1.43141361 |
| 27 | BRAF | 1.39932328 |
| 28 | MAPK12 | 1.38278533 |
| 29 | MAPK11 | 1.29964378 |
| 30 | CDK12 | 1.27286222 |
| 31 | EIF2AK1 | 1.27185530 |
| 32 | RAF1 | 1.26138416 |
| 33 | MAP3K4 | 1.23383111 |
| 34 | PRKD1 | 1.22816716 |
| 35 | LYN | 1.13802174 |
| 36 | CAMK2B | 1.06863310 |
| 37 | IKBKB | 1.04610059 |
| 38 | PBK | 0.99050702 |
| 39 | FYN | 0.99011491 |
| 40 | ICK | 0.93032252 |
| 41 | CAMK2G | 0.92350200 |
| 42 | DAPK1 | 0.91725375 |
| 43 | JAK1 | 0.87531388 |
| 44 | DAPK3 | 0.85223612 |
| 45 | MAP4K2 | 0.84653751 |
| 46 | SYK | 0.84207672 |
| 47 | STK38 | 0.82297405 |
| 48 | ZAP70 | 0.79761364 |
| 49 | LCK | 0.78876595 |
| 50 | PRKCE | 0.78556985 |
| 51 | DMPK | 0.77715779 |
| 52 | STK39 | 0.77367147 |
| 53 | DYRK1B | 0.75653242 |
| 54 | KSR2 | 0.75503233 |
| 55 | TAOK1 | 0.74914064 |
| 56 | MAP3K9 | 0.69684947 |
| 57 | YES1 | 0.69418020 |
| 58 | TESK2 | 0.64504873 |
| 59 | JAK2 | 0.64392465 |
| 60 | BRD4 | 0.62871918 |
| 61 | CAMK1 | 0.62476789 |
| 62 | TBK1 | 0.62014688 |
| 63 | MST4 | 0.59577705 |
| 64 | RIPK4 | 0.58105474 |
| 65 | WNK4 | 0.58022781 |
| 66 | PRKCQ | 0.56767130 |
| 67 | MAPK4 | 0.56363314 |
| 68 | RET | 0.54804484 |
| 69 | PRKCD | 0.54361403 |
| 70 | PRKD3 | 0.53410769 |
| 71 | MAP3K11 | 0.53156048 |
| 72 | ROCK2 | 0.52962385 |
| 73 | PDGFRA | 0.51042883 |
| 74 | PAK1 | 0.50929585 |
| 75 | KSR1 | 0.49758909 |
| 76 | FLT3 | 0.49252305 |
| 77 | ZAK | 0.47637840 |
| 78 | BTK | 0.46327555 |
| 79 | EPHB2 | 0.45995361 |
| 80 | DYRK1A | 0.45183655 |
| 81 | MST1R | 0.45152302 |
| 82 | GRK1 | 0.42834907 |
| 83 | IKBKE | 0.42627785 |
| 84 | PINK1 | 0.40783352 |
| 85 | RPS6KA4 | 0.40270024 |
| 86 | MAP2K3 | 0.39892286 |
| 87 | CDK3 | 0.39337338 |
| 88 | CDK14 | 0.38725380 |
| 89 | CAMK2D | 0.38577820 |
| 90 | PRKCZ | 0.37604371 |
| 91 | PTK2B | 0.36068763 |
| 92 | TEC | 0.35629093 |
| 93 | ADRBK1 | 0.33842647 |
| 94 | CSK | 0.33090928 |
| 95 | CAMK2A | 0.32832957 |
| 96 | CDK5 | 0.29533720 |
| 97 | CSNK1D | 0.28615249 |
| 98 | PRKAA1 | 0.27109597 |
| 99 | RPS6KA2 | 0.26694376 |
| 100 | NTRK3 | 0.25903539 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 4.30624009 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.39812266 |
| 3 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 3.01330437 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.82744592 |
| 5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.65229970 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.57792852 |
| 7 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.38043782 |
| 8 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.36252538 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.35634514 |
| 10 | Asthma_Homo sapiens_hsa05310 | 2.30971876 |
| 11 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.22275125 |
| 12 | Leishmaniasis_Homo sapiens_hsa05140 | 1.82916237 |
| 13 | Viral myocarditis_Homo sapiens_hsa05416 | 1.82812713 |
| 14 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.74614379 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.72383971 |
| 16 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.66577131 |
| 17 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.63464544 |
| 18 | Base excision repair_Homo sapiens_hsa03410 | 1.58303026 |
| 19 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.57068803 |
| 20 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.56309736 |
| 21 | Mineral absorption_Homo sapiens_hsa04978 | 1.55565829 |
| 22 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.45434904 |
| 23 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.36786807 |
| 24 | Tuberculosis_Homo sapiens_hsa05152 | 1.35597010 |
| 25 | Morphine addiction_Homo sapiens_hsa05032 | 1.33706208 |
| 26 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.30379301 |
| 27 | Mismatch repair_Homo sapiens_hsa03430 | 1.27919512 |
| 28 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.21069100 |
| 29 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.20172643 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.17916940 |
| 31 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.16576134 |
| 32 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.15375665 |
| 33 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.10184311 |
| 34 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.10148745 |
| 35 | Phagosome_Homo sapiens_hsa04145 | 1.09453092 |
| 36 | Cocaine addiction_Homo sapiens_hsa05030 | 1.09306974 |
| 37 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.08430620 |
| 38 | Shigellosis_Homo sapiens_hsa05131 | 1.05907416 |
| 39 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.03114437 |
| 40 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.02842006 |
| 41 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.01297948 |
| 42 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.99544192 |
| 43 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.97459716 |
| 44 | Influenza A_Homo sapiens_hsa05164 | 0.94711167 |
| 45 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.92361965 |
| 46 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.87824702 |
| 47 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.87269008 |
| 48 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.85804014 |
| 49 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.79035932 |
| 50 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.78238870 |
| 51 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.77502451 |
| 52 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.76338098 |
| 53 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.75212385 |
| 54 | Legionellosis_Homo sapiens_hsa05134 | 0.74139282 |
| 55 | Salmonella infection_Homo sapiens_hsa05132 | 0.73827164 |
| 56 | HTLV-I infection_Homo sapiens_hsa05166 | 0.73743679 |
| 57 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.72955341 |
| 58 | Measles_Homo sapiens_hsa05162 | 0.72238697 |
| 59 | Proteasome_Homo sapiens_hsa03050 | 0.71190547 |
| 60 | Endocytosis_Homo sapiens_hsa04144 | 0.70610594 |
| 61 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.67877677 |
| 62 | RNA polymerase_Homo sapiens_hsa03020 | 0.65701069 |
| 63 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.65106005 |
| 64 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.64762157 |
| 65 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.61723107 |
| 66 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.61223481 |
| 67 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.61170850 |
| 68 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.59825858 |
| 69 | Malaria_Homo sapiens_hsa05144 | 0.59807904 |
| 70 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.58903372 |
| 71 | Hepatitis C_Homo sapiens_hsa05160 | 0.55066328 |
| 72 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.54348487 |
| 73 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.54001665 |
| 74 | Nicotine addiction_Homo sapiens_hsa05033 | 0.53825988 |
| 75 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.53776379 |
| 76 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.53141082 |
| 77 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.52953507 |
| 78 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.52697692 |
| 79 | Hepatitis B_Homo sapiens_hsa05161 | 0.49795174 |
| 80 | Olfactory transduction_Homo sapiens_hsa04740 | 0.48134508 |
| 81 | Protein export_Homo sapiens_hsa03060 | 0.46675696 |
| 82 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.46673270 |
| 83 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.45457321 |
| 84 | Circadian rhythm_Homo sapiens_hsa04710 | 0.41953065 |
| 85 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.41738440 |
| 86 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.39262581 |
| 87 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.38675699 |
| 88 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.37995293 |
| 89 | Alcoholism_Homo sapiens_hsa05034 | 0.37776680 |
| 90 | Galactose metabolism_Homo sapiens_hsa00052 | 0.36014830 |
| 91 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.35536738 |
| 92 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.34792984 |
| 93 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.33152152 |
| 94 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.33107301 |
| 95 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.32702783 |
| 96 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.29291282 |
| 97 | DNA replication_Homo sapiens_hsa03030 | 0.28647033 |
| 98 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.27223069 |
| 99 | Colorectal cancer_Homo sapiens_hsa05210 | 0.27064965 |
| 100 | Homologous recombination_Homo sapiens_hsa03440 | 0.26689015 |

