MYO5C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1surfactant homeostasis (GO:0043129)6.75410389
2intestinal epithelial cell development (GO:0060576)6.57323318
3branching involved in prostate gland morphogenesis (GO:0060442)6.16450127
4UDP-N-acetylglucosamine metabolic process (GO:0006047)5.79847086
5chemical homeostasis within a tissue (GO:0048875)5.65021114
6hemidesmosome assembly (GO:0031581)5.56366103
7lung secretory cell differentiation (GO:0061140)5.32271656
8axonemal dynein complex assembly (GO:0070286)5.11292801
9bundle of His cell to Purkinje myocyte communication (GO:0086069)5.01751107
10prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060524.95395350
11maintenance of protein localization in endoplasmic reticulum (GO:0035437)4.94764549
12Golgi transport vesicle coating (GO:0048200)4.85753386
13COPI coating of Golgi vesicle (GO:0048205)4.85753386
14epithelial cell differentiation involved in prostate gland development (GO:0060742)4.79663012
15cilium or flagellum-dependent cell motility (GO:0001539)4.77259714
16L-fucose catabolic process (GO:0042355)4.60050237
17fucose catabolic process (GO:0019317)4.60050237
18L-fucose metabolic process (GO:0042354)4.60050237
19protein retention in ER lumen (GO:0006621)4.53063144
20peptide catabolic process (GO:0043171)4.31422742
21cilium movement (GO:0003341)4.30778830
22transcytosis (GO:0045056)4.24384796
23calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)4.18286604
24regulation of branching involved in prostate gland morphogenesis (GO:0060687)4.15978944
25intestinal cholesterol absorption (GO:0030299)4.05440505
26primary alcohol catabolic process (GO:0034310)3.98681968
27tight junction assembly (GO:0070830)3.97423713
28digestion (GO:0007586)3.90974643
29prostate gland epithelium morphogenesis (GO:0060740)3.88012373
30exocrine pancreas development (GO:0031017)3.83879450
31biotin metabolic process (GO:0006768)3.82654615
32artery development (GO:0060840)3.80167397
33epithelial cell maturation (GO:0002070)3.79094028
34regulation of centriole replication (GO:0046599)3.73002219
35motile cilium assembly (GO:0044458)3.72477818
36fucose metabolic process (GO:0006004)3.71835061
37establishment of apical/basal cell polarity (GO:0035089)3.69637585
38epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.67686049
39angiotensin maturation (GO:0002003)3.65767954
40lung lobe morphogenesis (GO:0060463)3.62349926
41N-glycan processing (GO:0006491)3.61232821
42regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)3.59304810
43hepatocyte apoptotic process (GO:0097284)3.56050150
44activation of signaling protein activity involved in unfolded protein response (GO:0006987)3.53871979
45O-glycan processing (GO:0016266)3.53147448
46positive regulation of keratinocyte differentiation (GO:0045618)3.52006668
47pattern specification involved in kidney development (GO:0061004)3.50847995
48trivalent inorganic anion homeostasis (GO:0072506)3.48453370
49phosphate ion homeostasis (GO:0055062)3.48453370
50iron ion import (GO:0097286)3.47320280
51positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003603.45838893
52valine metabolic process (GO:0006573)3.43380024
53ER overload response (GO:0006983)3.36732850
54epithelial cilium movement (GO:0003351)3.36292570
55sulfate transmembrane transport (GO:1902358)3.35869123
56regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.35575500
57lung cell differentiation (GO:0060479)3.35233921
58regulation of establishment or maintenance of cell polarity (GO:0032878)3.34570228
59ethanol metabolic process (GO:0006067)3.33875192
60regulation of cell proliferation involved in kidney development (GO:1901722)3.33872878
61positive regulation of nuclease activity (GO:0032075)3.33293438
62multicellular organismal water homeostasis (GO:0050891)3.32228290
63regulation of keratinocyte differentiation (GO:0045616)3.31564366
64striated muscle atrophy (GO:0014891)3.31544533
65hypotonic response (GO:0006971)3.30617792
66hormone catabolic process (GO:0042447)3.30534764
67keratinocyte development (GO:0003334)3.26464417
68glandular epithelial cell differentiation (GO:0002067)3.26236047
69intestinal absorption (GO:0050892)3.26093632
70ear development (GO:0043583)3.24080392
71columnar/cuboidal epithelial cell development (GO:0002066)3.19797808
72regulation of water loss via skin (GO:0033561)3.18238885
73epithelial cell-cell adhesion (GO:0090136)3.16126071
74nucleotide-sugar metabolic process (GO:0009225)3.14616303
75desmosome organization (GO:0002934)3.14332728
76skeletal muscle adaptation (GO:0043501)3.13277885
77lung epithelial cell differentiation (GO:0060487)3.12981804
78pyrimidine-containing compound transmembrane transport (GO:0072531)3.12562347
79maintenance of gastrointestinal epithelium (GO:0030277)3.12387089
80positive regulation of epidermal cell differentiation (GO:0045606)3.10481302
81axoneme assembly (GO:0035082)3.09242657
82nucleotide-sugar biosynthetic process (GO:0009226)3.08117653
83cytoskeletal anchoring at plasma membrane (GO:0007016)3.08036258
84endoplasmic reticulum unfolded protein response (GO:0030968)3.07705716
85establishment or maintenance of monopolar cell polarity (GO:0061339)3.07032846
86establishment of monopolar cell polarity (GO:0061162)3.07032846
87positive regulation of glycoprotein metabolic process (GO:1903020)3.03942722
88regulation of establishment of cell polarity (GO:2000114)3.03924016
89regulation of nuclease activity (GO:0032069)3.02876411
90positive regulation of glycoprotein biosynthetic process (GO:0010560)3.00637455
91mannose metabolic process (GO:0006013)2.99953297
92ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)2.99952436
93cellular response to unfolded protein (GO:0034620)2.97521171
94thyroid hormone generation (GO:0006590)2.97046584
95regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.96523116
96mesodermal cell differentiation (GO:0048333)2.95097333
97antibacterial humoral response (GO:0019731)2.94903530
98establishment of epithelial cell polarity (GO:0090162)2.94452824
99regulation of hippo signaling (GO:0035330)2.94148739
100prostate gland growth (GO:0060736)2.92583093
101epithelial tube branching involved in lung morphogenesis (GO:0060441)2.92504362
102galactose catabolic process (GO:0019388)2.90983601
103protein autoprocessing (GO:0016540)2.90687830
104cellular zinc ion homeostasis (GO:0006882)2.90527698
105embryonic retina morphogenesis in camera-type eye (GO:0060059)2.90390545
106beta-amyloid metabolic process (GO:0050435)2.89885452
107nitric oxide biosynthetic process (GO:0006809)2.89467560
108response to endoplasmic reticulum stress (GO:0034976)2.89454260
109positive regulation of respiratory burst (GO:0060267)2.89065179
110water homeostasis (GO:0030104)2.88960961
111negative regulation of glycogen biosynthetic process (GO:0045719)2.86942367
112lung epithelium development (GO:0060428)2.85703951
113carnitine transport (GO:0015879)2.85616985
114amino-acid betaine transport (GO:0015838)2.85616985
115ER-nucleus signaling pathway (GO:0006984)2.84747396
116diterpenoid biosynthetic process (GO:0016102)2.83745809
117antimicrobial humoral response (GO:0019730)2.82850243
118auditory receptor cell differentiation (GO:0042491)2.82149842
119toxin transport (GO:1901998)2.81437455
120erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.80986305
121L-phenylalanine metabolic process (GO:0006558)2.80986305
122mitochondrion distribution (GO:0048311)2.80815186
123thyroid hormone metabolic process (GO:0042403)2.79802498
124muscle atrophy (GO:0014889)2.77049414
125vitamin transmembrane transport (GO:0035461)2.75623836
126zinc ion transmembrane transport (GO:0071577)2.75564512
127amyloid precursor protein catabolic process (GO:0042987)2.75157066
128quaternary ammonium group transport (GO:0015697)2.72550346
129norepinephrine metabolic process (GO:0042415)2.72365383
130regulation of interleukin-13 production (GO:0032656)2.72020312
131negative regulation of kidney development (GO:0090185)2.71431021
132positive regulation of establishment of protein localization to plasma membrane (GO:0090004)2.70874393
133polarized epithelial cell differentiation (GO:0030859)2.69643362
134retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.68366521
135negative regulation of cell fate commitment (GO:0010454)2.68167522
136cardiac right ventricle morphogenesis (GO:0003215)2.67813626
137regulation of podosome assembly (GO:0071801)2.67732423
138intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059)2.66278488
139regulation of centrosome duplication (GO:0010824)2.65914163
140cellular response to topologically incorrect protein (GO:0035967)2.65678712
141carnitine transmembrane transport (GO:1902603)2.65002413
142endocardial cushion development (GO:0003197)2.64721034
143mammary gland alveolus development (GO:0060749)2.64039672
144regulation of chemokine secretion (GO:0090196)2.63708213
145cell-cell junction assembly (GO:0007043)2.63532921
146branching involved in mammary gland duct morphogenesis (GO:0060444)2.60575361
147L-alpha-amino acid transmembrane transport (GO:1902475)2.60005024
148digestive system process (GO:0022600)2.59617708
149diol metabolic process (GO:0034311)2.59157832
150positive regulation of hormone metabolic process (GO:0032352)2.58780216
151transepithelial transport (GO:0070633)2.57500533
152zinc ion transport (GO:0006829)2.54447228
153branched-chain amino acid catabolic process (GO:0009083)2.54409773
154uterus development (GO:0060065)2.53019977
155sphingomyelin metabolic process (GO:0006684)2.51994843
156regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.50992649
157glutathione biosynthetic process (GO:0006750)2.47278877
158insulin-like growth factor receptor signaling pathway (GO:0048009)2.45116949
159regulation of fatty acid beta-oxidation (GO:0031998)2.43055543
160vagina development (GO:0060068)2.42610298
161establishment of skin barrier (GO:0061436)2.42031145
162response to food (GO:0032094)2.41674611
163Leydig cell differentiation (GO:0033327)2.40310433
164dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.38512176
165response to nitrosative stress (GO:0051409)2.34796170
166embryonic camera-type eye morphogenesis (GO:0048596)2.34365572
167glutathione derivative metabolic process (GO:1901685)2.33871584

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.30246975
2* SOX2_27498859_Chip-Seq_STOMACH_Mouse4.10728417
3ESR1_15608294_ChIP-ChIP_MCF-7_Human3.90599794
4ESR1_21235772_ChIP-Seq_MCF-7_Human3.85098206
5ESR1_20079471_ChIP-ChIP_T-47D_Human3.81835157
6ESR2_21235772_ChIP-Seq_MCF-7_Human3.38196039
7STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse3.35926999
8CDX2_20551321_ChIP-Seq_CACO-2_Human3.33835230
9GATA4_25053715_ChIP-Seq_YYC3_Human3.15783754
10SMAD4_19686287_ChIP-ChIP_HaCaT_Human3.13492166
11TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.94917988
12SOX2_20726797_ChIP-Seq_SW620_Human2.89910924
13GATA6_25053715_ChIP-Seq_YYC3_Human2.79247306
14* FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.78053845
15STAT6_21828071_ChIP-Seq_BEAS2B_Human2.75091098
16* ZNF217_24962896_ChIP-Seq_MCF-7_Human2.61215328
17PPAR_26484153_Chip-Seq_NCI-H1993_Human2.37549491
18STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.31258722
19RARG_19884340_ChIP-ChIP_MEFs_Mouse2.30545084
20KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human2.24017654
21GATA1_22025678_ChIP-Seq_K562_Human2.23037798
22SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.16907784
23SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.16907784
24SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse2.16627173
25* RUNX1_27514584_Chip-Seq_MCF-7_Human2.12183973
26ER_23166858_ChIP-Seq_MCF-7_Human2.11215671
27FOXO3_23340844_ChIP-Seq_DLD1_Human2.10873766
28ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.07417731
29AHR_22903824_ChIP-Seq_MCF-7_Human2.05291475
30* TFAP2C_20629094_ChIP-Seq_MCF-7_Human2.03908552
31AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.99804698
32ZNF263_19887448_ChIP-Seq_K562_Human1.95551894
33* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.95278941
34CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.94364248
35TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.93845357
36GATA2_21666600_ChIP-Seq_HMVEC_Human1.93699842
37PADI4_21655091_ChIP-ChIP_MCF-7_Human1.88855412
38CLOCK_20551151_ChIP-Seq_293T_Human1.82277809
39GATA3_24758297_ChIP-Seq_MCF-7_Human1.82029544
40FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.79921693
41TDRD3_21172665_ChIP-Seq_MCF-7_Human1.78370007
42TRIM28_21343339_ChIP-Seq_HEK293_Human1.74647366
43ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.73552250
44KLF5_25053715_ChIP-Seq_YYC3_Human1.73234069
45SALL1_21062744_ChIP-ChIP_HESCs_Human1.69571225
46RACK7_27058665_Chip-Seq_MCF-7_Human1.68636770
47ARNT_22903824_ChIP-Seq_MCF-7_Human1.65680208
48PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.64250705
49ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.63452178
50KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.62457233
51SOX9_24532713_ChIP-Seq_HFSC_Mouse1.59514343
52CDX2_19796622_ChIP-Seq_MESCs_Mouse1.58498708
53* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.55686197
54HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.55494219
55PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.54678626
56FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.54002501
57KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.49819247
58KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.49819247
59KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.49819247
60TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.46294557
61PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.44433530
62SALL4_18804426_ChIP-ChIP_XEN_Mouse1.43749047
63AR_21909140_ChIP-Seq_LNCAP_Human1.43568734
64* FOXA2_19822575_ChIP-Seq_HepG2_Human1.43507024
65FOXA1_25552417_ChIP-Seq_VCAP_Human1.40832706
66EP300_21415370_ChIP-Seq_HL-1_Mouse1.39824865
67EGR1_23403033_ChIP-Seq_LIVER_Mouse1.39760190
68ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.35421287
69NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.35365661
70ATF3_27146783_Chip-Seq_COLON_Human1.34507004
71CHD1_26751641_Chip-Seq_LNCaP_Human1.31961673
72LXR_22158963_ChIP-Seq_LIVER_Mouse1.31251404
73POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.30414631
74TCF4_18268006_ChIP-ChIP_LS174T_Human1.28558603
75HIF1A_21447827_ChIP-Seq_MCF-7_Human1.26670507
76FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.26657207
77KDM5A_27292631_Chip-Seq_BREAST_Human1.25964852
78CTNNB1_20460455_ChIP-Seq_HCT116_Human1.25637529
79CJUN_26792858_Chip-Seq_BT549_Human1.23327026
80PKCTHETA_26484144_Chip-Seq_BREAST_Human1.22363588
81PPARA_22158963_ChIP-Seq_LIVER_Mouse1.22246008
82NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.19452672
83SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.19178253
84TBX20_22080862_ChIP-Seq_HEART_Mouse1.19074134
85TBX20_22328084_ChIP-Seq_HEART_Mouse1.19074134
86HOXB7_26014856_ChIP-Seq_BT474_Human1.16749378
87SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.15007451
88P63_26484246_Chip-Seq_KERATINOCYTES_Human1.13928085
89CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.10912308
90PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.10747417
91* HNF4A_19822575_ChIP-Seq_HepG2_Human1.10108672
92ELF5_23300383_ChIP-Seq_T47D_Human1.09254284
93* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08473755
94CDX2_22108803_ChIP-Seq_LS180_Human1.07215618
95FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.06183120
96KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.05934591
97ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.05737457
98TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.04743854
99ISL1_27105846_Chip-Seq_CPCs_Mouse1.04424628
100CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.00899775
101TCF3_18692474_ChIP-Seq_MEFs_Mouse0.99012865
102CREB1_26743006_Chip-Seq_LNCaP_Human0.98628970
103* TP63_23658742_ChIP-Seq_EP156T_Human0.97988053
104* ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.96978142
105EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.96370619
106CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.95206361
107EGR1_19374776_ChIP-ChIP_THP-1_Human0.93610066
108E2F1_21310950_ChIP-Seq_MCF-7_Human0.92877593
109PIAS1_25552417_ChIP-Seq_VCAP_Human0.91639197
110AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.90372059
111ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.90236902
112RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.90201339
113ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.89538634
114* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.84846075
115TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.83983750
116RXR_22158963_ChIP-Seq_LIVER_Mouse0.83146032
117GATA2_19941826_ChIP-Seq_K562_Human0.83050422
118BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.82159024
119JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.81474051
120TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.81312475
121FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.76482943
122AR_20517297_ChIP-Seq_VCAP_Human0.70919023
123E2F7_22180533_ChIP-Seq_HELA_Human0.70823948
124ZFX_18555785_ChIP-Seq_MESCs_Mouse0.64166954
125TCF4_22108803_ChIP-Seq_LS180_Human0.63539565
126RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.62839133
127TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.62748701
128PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.62328202
129NR3C1_21868756_ChIP-Seq_MCF10A_Human0.61947354
130FOXA1_25329375_ChIP-Seq_VCAP_Human0.60573506
131FOXA1_27270436_Chip-Seq_PROSTATE_Human0.60573506
132ERA_21632823_ChIP-Seq_H3396_Human0.58620235
133TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.56579553

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle5.47092140
2MP0008004_abnormal_stomach_pH5.06415547
3MP0004264_abnormal_extraembryonic_tissu4.04391113
4MP0001666_abnormal_nutrient_absorption3.82394284
5MP0000537_abnormal_urethra_morphology3.70916556
6MP0004782_abnormal_surfactant_physiolog3.63458962
7MP0001873_stomach_inflammation3.29552880
8MP0005083_abnormal_biliary_tract3.12574683
9MP0006054_spinal_hemorrhage2.65321265
10MP0001664_abnormal_digestion2.56904883
11MP0005646_abnormal_pituitary_gland2.30229219
12MP0000566_synostosis2.30047386
13MP0005310_abnormal_salivary_gland2.28421303
14MP0010678_abnormal_skin_adnexa2.12509034
15MP0002166_altered_tumor_susceptibility2.07214849
16MP0003300_gastrointestinal_ulcer2.05672022
17MP0005220_abnormal_exocrine_pancreas2.00943537
18MP0001958_emphysema2.00694146
19MP0002009_preneoplasia1.99884329
20MP0010352_gastrointestinal_tract_polyps1.94702397
21MP0000462_abnormal_digestive_system1.90500726
22MP0003123_paternal_imprinting1.85991965
23MP0002909_abnormal_adrenal_gland1.83600194
24MP0000427_abnormal_hair_cycle1.82371789
25MP0000613_abnormal_salivary_gland1.78397886
26MP0008057_abnormal_DNA_replication1.77946805
27MP0002160_abnormal_reproductive_system1.76279948
28MP0010155_abnormal_intestine_physiology1.68834293
29MP0009780_abnormal_chondrocyte_physiolo1.67259380
30MP0000470_abnormal_stomach_morphology1.66972511
31MP0000490_abnormal_crypts_of1.63014608
32MP0002277_abnormal_respiratory_mucosa1.62004491
33MP0008995_early_reproductive_senescence1.60709713
34MP0003866_abnormal_defecation1.58387497
35MP0002006_tumorigenesis1.53575768
36MP0010386_abnormal_urinary_bladder1.52441122
37MP0005647_abnormal_sex_gland1.51127564
38MP0001663_abnormal_digestive_system1.50394783
39MP0002098_abnormal_vibrissa_morphology1.49558751
40MP0005381_digestive/alimentary_phenotyp1.46280887
41MP0003705_abnormal_hypodermis_morpholog1.44679420
42MP0003868_abnormal_feces_composition1.42165451
43MP0002876_abnormal_thyroid_physiology1.41493467
44MP0001765_abnormal_ion_homeostasis1.40386324
45MP0004043_abnormal_pH_regulation1.38448307
46MP0005365_abnormal_bile_salt1.36991322
47MP0000383_abnormal_hair_follicle1.28014282
48MP0002796_impaired_skin_barrier1.27476615
49MP0002254_reproductive_system_inflammat1.26965544
50MP0002132_abnormal_respiratory_system1.26547369
51MP0001881_abnormal_mammary_gland1.26173233
52MP0000516_abnormal_urinary_system1.24840177
53MP0005367_renal/urinary_system_phenotyp1.24840177
54MP0000477_abnormal_intestine_morphology1.23721271
55MP0002138_abnormal_hepatobiliary_system1.23078985
56MP0001944_abnormal_pancreas_morphology1.22598631
57MP0000013_abnormal_adipose_tissue1.22205530
58MP0003941_abnormal_skin_development1.20860670
59MP0009643_abnormal_urine_homeostasis1.20304477
60MP0003936_abnormal_reproductive_system1.18719559
61MP0003566_abnormal_cell_adhesion1.18290611
62MP0003693_abnormal_embryo_hatching1.17289709
63MP0001727_abnormal_embryo_implantation1.15603962
64MP0001849_ear_inflammation1.13616842
65MP0003943_abnormal_hepatobiliary_system1.12676031
66MP0003195_calcinosis1.12295867
67MP0004019_abnormal_vitamin_homeostasis1.11822129
68MP0009384_cardiac_valve_regurgitation1.10645552
69MP0010329_abnormal_lipoprotein_level1.09908302
70MP0003890_abnormal_embryonic-extraembry1.07658023
71MP0000627_abnormal_mammary_gland1.07611081
72MP0005084_abnormal_gallbladder_morpholo1.06811599
73MP0002295_abnormal_pulmonary_circulatio1.06350809
74MP0005085_abnormal_gallbladder_physiolo1.05841331
75MP0000465_gastrointestinal_hemorrhage1.05619808
76MP0000534_abnormal_ureter_morphology1.04527129
77MP0000579_abnormal_nail_morphology1.04004756
78MP0000538_abnormal_urinary_bladder1.03768707
79MP0008961_abnormal_basal_metabolism1.03753154
80MP0004272_abnormal_basement_membrane1.01567380
81MP0005187_abnormal_penis_morphology1.01038065
82MP0005167_abnormal_blood-brain_barrier1.00546484
83MP0000467_abnormal_esophagus_morphology0.99407170
84MP0003315_abnormal_perineum_morphology0.98986994
85MP0001346_abnormal_lacrimal_gland0.98339053
86MP0000681_abnormal_thyroid_gland0.98092402
87MP0001756_abnormal_urination0.94129190
88MP0010307_abnormal_tumor_latency0.93851902
89MP0005636_abnormal_mineral_homeostasis0.93626392
90MP0005248_abnormal_Harderian_gland0.92549736
91MP0002060_abnormal_skin_morphology0.90815988
92MP0008872_abnormal_physiological_respon0.85380851
93MP0003453_abnormal_keratinocyte_physiol0.85191953
94MP0001919_abnormal_reproductive_system0.84323176
95MP0010771_integument_phenotype0.83603908
96MP0004947_skin_inflammation0.83237418
97MP0009703_decreased_birth_body0.82877328
98MP0001177_atelectasis0.82163535
99MP0003937_abnormal_limbs/digits/tail_de0.81943364
100MP0003045_fibrosis0.81762227
101MP0002693_abnormal_pancreas_physiology0.81494702
102MP0005408_hypopigmentation0.80575967
103MP0005389_reproductive_system_phenotype0.79916445
104MP0009672_abnormal_birth_weight0.79191894
105MP0002136_abnormal_kidney_physiology0.78703469
106MP0001216_abnormal_epidermal_layer0.77935321
107MP0002234_abnormal_pharynx_morphology0.77286577
108MP0003183_abnormal_peptide_metabolism0.77247480
109MP0005409_darkened_coat_color0.76444263
110MP0004185_abnormal_adipocyte_glucose0.76383421
111MP0005165_increased_susceptibility_to0.76309067
112MP0004233_abnormal_muscle_weight0.76273952
113MP0004957_abnormal_blastocyst_morpholog0.76148697
114MP0002133_abnormal_respiratory_system0.75779265
115MP0005388_respiratory_system_phenotype0.75779265
116MP0003115_abnormal_respiratory_system0.75129524
117MP0000003_abnormal_adipose_tissue0.74839274
118MP0001661_extended_life_span0.74784739
119MP0002118_abnormal_lipid_homeostasis0.73551875
120MP0005332_abnormal_amino_acid0.72657956
121MP0005166_decreased_susceptibility_to0.72253527
122MP0002088_abnormal_embryonic_growth/wei0.72075994
123MP0000762_abnormal_tongue_morphology0.72020757
124MP0003786_premature_aging0.70812740
125MP0001879_abnormal_lymphatic_vessel0.67737165
126MP0002139_abnormal_hepatobiliary_system0.67708334
127MP0003942_abnormal_urinary_system0.67614571
128MP0003953_abnormal_hormone_level0.67080384
129MP0005275_abnormal_skin_tensile0.66314447
130MP0003984_embryonic_growth_retardation0.66146883
131MP0001672_abnormal_embryogenesis/_devel0.64836877
132MP0005380_embryogenesis_phenotype0.64836877
133MP0004133_heterotaxia0.64646584
134MP0010368_abnormal_lymphatic_system0.64597945
135MP0008875_abnormal_xenobiotic_pharmacok0.64272991
136MP0004381_abnormal_hair_follicle0.64058964
137MP0005023_abnormal_wound_healing0.63895042
138MP0000647_abnormal_sebaceous_gland0.63479599
139MP0002249_abnormal_larynx_morphology0.63117165
140MP0000377_abnormal_hair_follicle0.62927726
141MP0004130_abnormal_muscle_cell0.62647913
142MP0003119_abnormal_digestive_system0.62246360
143MP0005501_abnormal_skin_physiology0.62170518
144MP0003638_abnormal_response/metabolism_0.60743360
145MP0002135_abnormal_kidney_morphology0.59567979
146MP0009764_decreased_sensitivity_to0.57736880
147MP0005058_abnormal_lysosome_morphology0.56962797
148MP0005076_abnormal_cell_differentiation0.56424331

Predicted human phenotypes

RankGene SetZ-score
1Interstitial pulmonary disease (HP:0006530)6.03486020
2Onycholysis (HP:0001806)5.55621412
3Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.10541133
4Right ventricular cardiomyopathy (HP:0011663)5.08157829
5Hyperactive renin-angiotensin system (HP:0000841)4.99695373
6Absent/shortened dynein arms (HP:0200106)4.46846221
7Dynein arm defect of respiratory motile cilia (HP:0012255)4.46846221
8Abnormality of cochlea (HP:0000375)4.45245029
9Abnormal respiratory motile cilium morphology (HP:0005938)4.28539967
10Abnormal respiratory epithelium morphology (HP:0012253)4.28539967
11Abnormal respiratory motile cilium physiology (HP:0012261)4.22603252
12Milia (HP:0001056)4.20818298
13Rhinitis (HP:0012384)4.19027723
14Abnormal ciliary motility (HP:0012262)4.11323697
15Rectal prolapse (HP:0002035)3.87547306
16J-shaped sella turcica (HP:0002680)3.85414471
17Atrophic scars (HP:0001075)3.67887148
18Abnormality of chloride homeostasis (HP:0011422)3.40730658
19Asymmetry of the thorax (HP:0001555)3.34343792
20Gout (HP:0001997)3.27047559
21Micronodular cirrhosis (HP:0001413)3.26766408
22Exocrine pancreatic insufficiency (HP:0001738)3.21734523
23Abnormality of the 2nd finger (HP:0004100)3.15266978
24Biliary tract neoplasm (HP:0100574)3.14556833
25Tubulointerstitial fibrosis (HP:0005576)3.13006552
26Bronchiectasis (HP:0002110)3.05902272
27Pili torti (HP:0003777)3.05690112
28Renal salt wasting (HP:0000127)3.04400341
29Septate vagina (HP:0001153)3.00557324
30Facial shape deformation (HP:0011334)2.99323358
31Potter facies (HP:0002009)2.99323358
32Chromosomal breakage induced by crosslinking agents (HP:0003221)2.87146050
33Chromsome breakage (HP:0040012)2.83400631
34Morphological abnormality of the inner ear (HP:0011390)2.79252965
35Hypoplasia of the uterus (HP:0000013)2.78389615
36Fragile nails (HP:0001808)2.76434284
37Goiter (HP:0000853)2.72993752
38Amelogenesis imperfecta (HP:0000705)2.70784646
39Hypoplasia of dental enamel (HP:0006297)2.68703994
40Aplasia involving bones of the extremities (HP:0009825)2.68641175
41Aplasia involving bones of the upper limbs (HP:0009823)2.68641175
42Aplasia of the phalanges of the hand (HP:0009802)2.68641175
43Aortic aneurysm (HP:0004942)2.65403285
44Concave nail (HP:0001598)2.61684495
45Glomerulosclerosis (HP:0000096)2.60916082
46Dehydration (HP:0001944)2.51949641
47Tachypnea (HP:0002789)2.50868133
48Absent frontal sinuses (HP:0002688)2.50226490
49Esophageal varix (HP:0002040)2.49526781
50Abnormal biliary tract morphology (HP:0012440)2.49225780
51Hyperkalemia (HP:0002153)2.49121316
52Abnormality of the phalanges of the 2nd finger (HP:0009541)2.48820488
53Mildly elevated creatine phosphokinase (HP:0008180)2.48757444
54Testicular atrophy (HP:0000029)2.47971413
55Tubulointerstitial nephritis (HP:0001970)2.47308536
56Curly hair (HP:0002212)2.47127741
57Vascular calcification (HP:0004934)2.45749290
58Microglossia (HP:0000171)2.44249227
59Hyperphosphatemia (HP:0002905)2.43755787
60Abdominal distention (HP:0003270)2.42619751
61Plantar hyperkeratosis (HP:0007556)2.41598582
62Steatorrhea (HP:0002570)2.41031570
63Abnormality of the nasal septum (HP:0000419)2.40687656
64Subacute progressive viral hepatitis (HP:0006572)2.39081737
65Macroorchidism (HP:0000053)2.38315071
66Respiratory distress (HP:0002098)2.37429867
67Abnormality of the gastric mucosa (HP:0004295)2.36300841
68Chronic bronchitis (HP:0004469)2.35441177
69Enlarged penis (HP:0000040)2.35240781
70Pustule (HP:0200039)2.34075867
71Flat acetabular roof (HP:0003180)2.31773027
72Colon cancer (HP:0003003)2.30200003
73Germ cell neoplasia (HP:0100728)2.30081883
74Hematochezia (HP:0002573)2.29789112
75Hypoplasia of the ulna (HP:0003022)2.29360235
76Hyperaldosteronism (HP:0000859)2.28916440
77Papillary thyroid carcinoma (HP:0002895)2.28796771
78Fibular aplasia (HP:0002990)2.28263572
79Decreased circulating renin level (HP:0003351)2.26903074
80Congenital sensorineural hearing impairment (HP:0008527)2.25819949
81Progressive sensorineural hearing impairment (HP:0000408)2.25576171
82Ulnar bowing (HP:0003031)2.23930027
83Hypoplastic nipples (HP:0002557)2.23432347
84Short hallux (HP:0010109)2.22696302
85Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)2.22693631
86Long toe (HP:0010511)2.21649524
87Shawl scrotum (HP:0000049)2.20151241
88Focal segmental glomerulosclerosis (HP:0000097)2.17835042
89Abnormal pancreas size (HP:0012094)2.15762944
90Ketoacidosis (HP:0001993)2.15021704
91Fat malabsorption (HP:0002630)2.14694170
92Ileus (HP:0002595)2.10317849
93Aplasia/Hypoplasia of the hallux (HP:0008362)2.09318868
94Malnutrition (HP:0004395)2.08728070
95Cone-rod dystrophy (HP:0000548)2.07976743
96Esophageal atresia (HP:0002032)2.07496852
97Woolly hair (HP:0002224)2.07439055
98Intrahepatic cholestasis (HP:0001406)2.06639396
99Thyroid carcinoma (HP:0002890)2.05792464
100Bowed forearm bones (HP:0003956)2.04697948
101Bowing of the arm (HP:0006488)2.04697948
102Infertility (HP:0000789)2.03029435
103Uterine neoplasm (HP:0010784)2.01932193
104Hypoplastic labia majora (HP:0000059)2.01861986
105Hyperglycinuria (HP:0003108)2.01369899
106Bronchitis (HP:0012387)2.00811228
107Subcapsular cataract (HP:0000523)2.00688013
108Abnormal foot bone ossification (HP:0010675)2.00087498
109Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.99049056
110Abnormality of the renal cortex (HP:0011035)1.98667401
111Symphalangism affecting the phalanges of the hand (HP:0009773)1.98022000
112Malignant gastrointestinal tract tumors (HP:0006749)1.96876150
113Gastrointestinal carcinoma (HP:0002672)1.96876150
114Abnormality of the middle phalanges of the toes (HP:0010183)1.96604899
115Ureteral stenosis (HP:0000071)1.96544499
116Hypoplasia of the pons (HP:0012110)1.96221773
117Breast carcinoma (HP:0003002)1.95988128
118Radial bowing (HP:0002986)1.95552203
119Hypotension (HP:0002615)1.95265055
120Tubular atrophy (HP:0000092)1.95074262
121Cystic liver disease (HP:0006706)1.93648570
122Ureteral obstruction (HP:0006000)1.91906777
123Neoplasm of the small intestine (HP:0100833)1.91638462
124Abnormality of renin-angiotensin system (HP:0000847)1.90276089
125Hypoglycemic coma (HP:0001325)1.90239524
126Deformed sella turcica (HP:0002681)1.89912317
127Pancreatic cysts (HP:0001737)1.89233146
128Ketosis (HP:0001946)1.88790254
129Sparse lateral eyebrow (HP:0005338)1.88074104
130Aplasia/Hypoplasia of the tongue (HP:0010295)1.87775802
131Progressive hearing impairment (HP:0001730)1.87245962
132Abnormality of small intestinal villus morphology (HP:0011472)1.87156381
133Villous atrophy (HP:0011473)1.87156381
134Abnormality of the dental root (HP:0006486)1.86520108
135Taurodontia (HP:0000679)1.86520108
136Abnormality of permanent molar morphology (HP:0011071)1.86520108
137Testicular neoplasm (HP:0010788)1.86517219
138Lip pit (HP:0100267)1.85286685
139Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.84933392
140Aplasia/Hypoplasia of the ulna (HP:0006495)1.84379791
141Hyponatremia (HP:0002902)1.83851656
142Abnormal hair laboratory examination (HP:0003328)1.83772893
143Vacuolated lymphocytes (HP:0001922)1.83527729
144Cardiovascular calcification (HP:0011915)1.82192706
145Neoplasm of the rectum (HP:0100743)1.81621673
146Adactyly (HP:0009776)1.81262102
147Abnormal tarsal ossification (HP:0008369)1.81067076
148Abnormality of monocarboxylic acid metabolism (HP:0010996)1.80338040
149Abnormality of the proximal phalanges of the hand (HP:0009834)1.79635636
150Hypothermia (HP:0002045)1.78535004
151Abnormality of the dental pulp (HP:0006479)1.76310944
152Hyperglycemia (HP:0003074)1.73161431
153High pitched voice (HP:0001620)1.73121807
154Chronic hepatic failure (HP:0100626)1.71255631
155True hermaphroditism (HP:0010459)1.71214729
156Abnormality of aromatic amino acid family metabolism (HP:0004338)1.71205355
157Abnormality of the distal phalanges of the toes (HP:0010182)1.68387587
158Abnormality of the frontal sinuses (HP:0002687)1.68351160
159Conjugated hyperbilirubinemia (HP:0002908)1.67730909
160Spinal cord compression (HP:0002176)1.67611405
161Deep philtrum (HP:0002002)1.61777033
162Abnormality of the renal medulla (HP:0100957)1.61454543
163Abnormal cartilage morphology (HP:0002763)1.60134303
164Chronic sinusitis (HP:0011109)1.58930460
165Abnormality of molar (HP:0011077)1.58026359
166Abnormality of molar morphology (HP:0011070)1.58026359
167Hyperinsulinemic hypoglycemia (HP:0000825)1.56416253
168Pancreatic fibrosis (HP:0100732)1.56242507
169Abnormality of the preputium (HP:0100587)1.56117939
170Abnormality of vitamin metabolism (HP:0100508)1.55940558
171Hypoglycemic seizures (HP:0002173)1.54536904
172Advanced eruption of teeth (HP:0006288)1.52661179

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST45.11865970
2FRK4.24506457
3AKT34.06820481
4STK393.58955256
5LMTK23.40160044
6EPHA23.39766693
7ERN13.33144817
8TAOK32.87906537
9LATS12.80479031
10OXSR12.02698492
11BCKDK2.00487292
12MST1R1.93505309
13FER1.92699847
14LRRK21.88539796
15RPS6KB21.88182158
16MYLK1.82857471
17PIK3CA1.81951868
18PTK61.77446800
19EEF2K1.74252332
20SIK11.74153718
21SMG11.71192703
22STK101.69627586
23MAP2K21.69303745
24MAP3K21.67719922
25TRIB31.67029870
26MAPK151.63692992
27MUSK1.55402785
28EIF2AK11.51089760
29RIPK11.48907868
30PKN21.46928272
31NUAK11.42909036
32NME11.26107445
33TTN1.24992561
34MAP2K31.23410546
35TAF11.22973103
36TIE11.22754347
37MAPKAPK31.18766833
38TESK11.17602552
39PDK21.15239362
40BRSK21.12723676
41MET1.11580722
42MAP2K61.10962853
43PAK41.10640516
44EPHB21.10294802
45FGFR41.03748194
46PIK3CG1.03731221
47TRPM70.98773182
48PRKCI0.98585942
49VRK20.97686542
50TSSK60.93873120
51BMPR1B0.93231560
52CAMK1D0.92914875
53TTK0.92277639
54TGFBR20.92084014
55PBK0.91046776
56ZAP700.90746368
57PRKG20.88719295
58MAP3K70.88456460
59FGFR20.88227870
60DMPK0.87655387
61RPS6KB10.86424130
62MAP2K10.84973201
63STK30.82698919
64GRK10.78524374
65TRIM280.78431132
66PDGFRB0.76952695
67CDK70.76218355
68MATK0.74811355
69CDK120.72911455
70STK240.72036117
71STK38L0.69158006
72PTK20.68228283
73PDK40.64968095
74PDK30.64968095
75EPHB10.63255949
76SCYL20.63111184
77IRAK30.61038658
78INSRR0.58441305
79MAP3K30.58385357
80EIF2AK20.57033332
81CDK60.55113282
82HIPK20.54627080
83ERBB20.53428270
84MAPKAPK50.53303678
85DAPK20.52503411
86EIF2AK30.51593960
87WNK40.50377106
88DDR20.50281202
89DAPK10.50114744
90MELK0.50060049
91FGFR10.47330849
92TNK20.46997166
93CDK80.46622277
94CSNK1E0.46062258
95MKNK20.44536819
96CAMK1G0.42334251
97ILK0.41648265
98PAK20.41247003
99PDGFRA0.40359510
100TGFBR10.40121111
101CHUK0.39005675
102MAP3K80.37884786
103AURKB0.36873213
104PNCK0.35361193
105ROCK10.34616815
106FLT30.33744478
107NEK90.33495931
108ERBB40.32494216
109ZAK0.32482240
110JAK30.31898804
111PDPK10.31853998
112ATR0.30226019
113BMX0.30127538
114MTOR0.29715803
115PRKCE0.29454493
116PLK10.27799910
117PRKAA20.26587454
118MAPKAPK20.26400983
119RPS6KA40.25265247
120STK380.25161258
121AKT20.24595808
122RPS6KA20.24466119
123MAP3K120.24357093
124EGFR0.24276176
125BRD40.23157060
126CSNK1G10.22915536
127CSNK1D0.22802050
128SGK30.22390214
129RET0.22023298
130ROCK20.19066636
131PHKG10.18397964
132PHKG20.18397964
133PRKD10.18206547
134FGFR30.13895864
135NEK60.11943180
136PRKAA10.11870419
137ERBB30.11543213

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006013.85074801
2Sulfur metabolism_Homo sapiens_hsa009203.80686279
3Pancreatic secretion_Homo sapiens_hsa049723.09373315
4Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.92563030
5Mineral absorption_Homo sapiens_hsa049782.58600698
6Protein digestion and absorption_Homo sapiens_hsa049742.44402921
7Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.35776219
8Renin-angiotensin system_Homo sapiens_hsa046142.31551090
9Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.28891994
10Tight junction_Homo sapiens_hsa045302.26874828
11Phenylalanine metabolism_Homo sapiens_hsa003602.26385042
12Adherens junction_Homo sapiens_hsa045202.14099265
13Vitamin B6 metabolism_Homo sapiens_hsa007502.09072893
14Fat digestion and absorption_Homo sapiens_hsa049752.06171359
15beta-Alanine metabolism_Homo sapiens_hsa004102.02296072
16Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.94053584
17Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.71227249
18Vibrio cholerae infection_Homo sapiens_hsa051101.67741097
19Tyrosine metabolism_Homo sapiens_hsa003501.66136295
20Tryptophan metabolism_Homo sapiens_hsa003801.64069894
21Protein export_Homo sapiens_hsa030601.63268943
22ECM-receptor interaction_Homo sapiens_hsa045121.58310539
23N-Glycan biosynthesis_Homo sapiens_hsa005101.52497753
24Leukocyte transendothelial migration_Homo sapiens_hsa046701.51679741
25Lysine degradation_Homo sapiens_hsa003101.50101904
26Endometrial cancer_Homo sapiens_hsa052131.49465688
27Bladder cancer_Homo sapiens_hsa052191.48951950
28Retinol metabolism_Homo sapiens_hsa008301.48010758
29Steroid hormone biosynthesis_Homo sapiens_hsa001401.46969317
30Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.45777038
31Small cell lung cancer_Homo sapiens_hsa052221.44983575
32Thyroid hormone synthesis_Homo sapiens_hsa049181.44346451
33Butanoate metabolism_Homo sapiens_hsa006501.43359947
34Cyanoamino acid metabolism_Homo sapiens_hsa004601.35701353
35Propanoate metabolism_Homo sapiens_hsa006401.34442267
36Fatty acid metabolism_Homo sapiens_hsa012121.34155878
37Hippo signaling pathway_Homo sapiens_hsa043901.32675544
38Nitrogen metabolism_Homo sapiens_hsa009101.28975331
39Maturity onset diabetes of the young_Homo sapiens_hsa049501.26804865
40Thyroid cancer_Homo sapiens_hsa052161.26730910
41Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.24708571
42Fatty acid biosynthesis_Homo sapiens_hsa000611.20410430
43Gastric acid secretion_Homo sapiens_hsa049711.19400372
44Caffeine metabolism_Homo sapiens_hsa002321.18923297
45Focal adhesion_Homo sapiens_hsa045101.18647413
46Other glycan degradation_Homo sapiens_hsa005111.18589277
47Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.15861773
48Peroxisome_Homo sapiens_hsa041461.15852475
49Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.15660344
50Hepatitis C_Homo sapiens_hsa051601.12099962
51Linoleic acid metabolism_Homo sapiens_hsa005911.06815710
52Fatty acid elongation_Homo sapiens_hsa000621.05194469
53Arginine biosynthesis_Homo sapiens_hsa002201.04916266
54Glycerolipid metabolism_Homo sapiens_hsa005611.04507057
55Fatty acid degradation_Homo sapiens_hsa000711.03645614
56Fructose and mannose metabolism_Homo sapiens_hsa000511.02254558
57Prostate cancer_Homo sapiens_hsa052150.99116754
58Non-homologous end-joining_Homo sapiens_hsa034500.97620719
59Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.95138227
60AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.94125381
61Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.92976760
62Amoebiasis_Homo sapiens_hsa051460.91963367
63Toxoplasmosis_Homo sapiens_hsa051450.91813362
64One carbon pool by folate_Homo sapiens_hsa006700.90270891
65Pentose and glucuronate interconversions_Homo sapiens_hsa000400.89731654
66Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.87025088
67Influenza A_Homo sapiens_hsa051640.86215424
68Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.84947212
69Glutathione metabolism_Homo sapiens_hsa004800.83929709
70Proteoglycans in cancer_Homo sapiens_hsa052050.83830501
71Inositol phosphate metabolism_Homo sapiens_hsa005620.83736471
72Galactose metabolism_Homo sapiens_hsa000520.78525893
73TGF-beta signaling pathway_Homo sapiens_hsa043500.76931182
74Glucagon signaling pathway_Homo sapiens_hsa049220.76732426
75Starch and sucrose metabolism_Homo sapiens_hsa005000.76477164
76alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.75516083
77Fanconi anemia pathway_Homo sapiens_hsa034600.74549590
78Primary bile acid biosynthesis_Homo sapiens_hsa001200.74182039
79Salivary secretion_Homo sapiens_hsa049700.73875223
80Steroid biosynthesis_Homo sapiens_hsa001000.73838818
81Circadian rhythm_Homo sapiens_hsa047100.72334419
82Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.71290398
83Drug metabolism - other enzymes_Homo sapiens_hsa009830.69378512
84Ovarian steroidogenesis_Homo sapiens_hsa049130.69238621
85Platelet activation_Homo sapiens_hsa046110.69221027
86Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.68522641
87Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.68134882
88Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.67549033
89Glycosaminoglycan degradation_Homo sapiens_hsa005310.66767505
90Folate biosynthesis_Homo sapiens_hsa007900.64823331
91Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.64709375
92Glycerophospholipid metabolism_Homo sapiens_hsa005640.64461838
93Prolactin signaling pathway_Homo sapiens_hsa049170.64401243
94Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.63989582
95Vitamin digestion and absorption_Homo sapiens_hsa049770.63808663
96Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.63018623
97RNA transport_Homo sapiens_hsa030130.62670152
98Insulin resistance_Homo sapiens_hsa049310.62331126
99Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.61379007
100Cysteine and methionine metabolism_Homo sapiens_hsa002700.60906392
101Pancreatic cancer_Homo sapiens_hsa052120.60532593
102Pathways in cancer_Homo sapiens_hsa052000.59116040
103Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.58330475
104PPAR signaling pathway_Homo sapiens_hsa033200.58033024
105Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.57304943
106Acute myeloid leukemia_Homo sapiens_hsa052210.57187444
107Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.56948972
108Ether lipid metabolism_Homo sapiens_hsa005650.55804415
1092-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.55129304
110Metabolic pathways_Homo sapiens_hsa011000.54715933
111Lysosome_Homo sapiens_hsa041420.53645745
112Melanoma_Homo sapiens_hsa052180.53362258
113Selenocompound metabolism_Homo sapiens_hsa004500.52836662
114Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.52612529
115Chronic myeloid leukemia_Homo sapiens_hsa052200.52595922
116Choline metabolism in cancer_Homo sapiens_hsa052310.50936692
117Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.48016971
118ABC transporters_Homo sapiens_hsa020100.47127291
119Notch signaling pathway_Homo sapiens_hsa043300.46355064
120Thyroid hormone signaling pathway_Homo sapiens_hsa049190.45737433
121Basal cell carcinoma_Homo sapiens_hsa052170.45592294
122Homologous recombination_Homo sapiens_hsa034400.45431543
123Regulation of actin cytoskeleton_Homo sapiens_hsa048100.44100441
124Salmonella infection_Homo sapiens_hsa051320.43847672
125AMPK signaling pathway_Homo sapiens_hsa041520.42635408
126Phosphatidylinositol signaling system_Homo sapiens_hsa040700.42598841
127Carbohydrate digestion and absorption_Homo sapiens_hsa049730.41754326
128Arachidonic acid metabolism_Homo sapiens_hsa005900.41143611
129NOD-like receptor signaling pathway_Homo sapiens_hsa046210.40901836
130Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.40807822
131mTOR signaling pathway_Homo sapiens_hsa041500.40668961
132Rap1 signaling pathway_Homo sapiens_hsa040150.40368685
133Insulin signaling pathway_Homo sapiens_hsa049100.40112492
134VEGF signaling pathway_Homo sapiens_hsa043700.40055069
135Chemical carcinogenesis_Homo sapiens_hsa052040.39475940
136Arginine and proline metabolism_Homo sapiens_hsa003300.39038691
137Bile secretion_Homo sapiens_hsa049760.38170559
138Histidine metabolism_Homo sapiens_hsa003400.37627059
139Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.36464154
140Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.36097609
141Legionellosis_Homo sapiens_hsa051340.36014833
142ErbB signaling pathway_Homo sapiens_hsa040120.35473562
143Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.34575118
144TNF signaling pathway_Homo sapiens_hsa046680.34556982
145Longevity regulating pathway - mammal_Homo sapiens_hsa042110.34385586
146Pyruvate metabolism_Homo sapiens_hsa006200.33327010
147Sphingolipid metabolism_Homo sapiens_hsa006000.33005561

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