MYOF

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell adhesion mediated by integrin (GO:0033627)5.72730496
2Golgi transport vesicle coating (GO:0048200)4.72106168
3COPI coating of Golgi vesicle (GO:0048205)4.72106168
4desmosome organization (GO:0002934)4.58423300
5apoptotic cell clearance (GO:0043277)4.54042815
6wound healing, spreading of epidermal cells (GO:0035313)4.42726354
7endodermal cell differentiation (GO:0035987)4.34715288
8chondrocyte proliferation (GO:0035988)4.17337069
9regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.98584179
10regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.89200009
11hemidesmosome assembly (GO:0031581)3.84447215
12skin morphogenesis (GO:0043589)3.82505622
13antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.80810361
14hypotonic response (GO:0006971)3.80230718
15cellular response to interferon-alpha (GO:0035457)3.75827202
16collagen fibril organization (GO:0030199)3.74194290
17positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.73210388
18barbed-end actin filament capping (GO:0051016)3.54863355
19negative regulation of fatty acid transport (GO:2000192)3.54225762
20maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.51874965
21positive regulation of endothelial cell apoptotic process (GO:2000353)3.49122947
22axon extension involved in axon guidance (GO:0048846)3.46597958
23neuron projection extension involved in neuron projection guidance (GO:1902284)3.46597958
24mesodermal cell differentiation (GO:0048333)3.44384249
25regulation of integrin activation (GO:0033623)3.43216983
26negative regulation of chondrocyte differentiation (GO:0032331)3.40542524
27wound healing, spreading of cells (GO:0044319)3.38878512
28positive regulation by symbiont of host defense response (GO:0052509)3.37815058
29modulation by symbiont of host defense response (GO:0052031)3.37815058
30modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.37815058
31modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.37815058
32positive regulation by organism of defense response of other organism involved in symbiotic interact3.37815058
33modulation by symbiont of host immune response (GO:0052553)3.37815058
34protein retention in ER lumen (GO:0006621)3.36766503
35cell-substrate adherens junction assembly (GO:0007045)3.34341829
36focal adhesion assembly (GO:0048041)3.34341829
37positive regulation of blood vessel endothelial cell migration (GO:0043536)3.34214042
38substrate-dependent cell migration (GO:0006929)3.33268601
39protein heterotrimerization (GO:0070208)3.33022075
40basement membrane organization (GO:0071711)3.21518396
41type B pancreatic cell proliferation (GO:0044342)3.20313006
42glomerular visceral epithelial cell development (GO:0072015)3.20298173
43positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr3.16747203
44cell-substrate junction assembly (GO:0007044)3.15906485
45kidney mesenchyme development (GO:0072074)3.15535375
46regulation of transforming growth factor beta2 production (GO:0032909)3.14326231
47regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)3.10526930
48mammary gland epithelial cell proliferation (GO:0033598)3.09532744
49membrane protein ectodomain proteolysis (GO:0006509)3.06700507
50epithelial cell-cell adhesion (GO:0090136)3.05363260
51positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.04175914
52neutrophil activation involved in immune response (GO:0002283)3.02221057
53muscle cell migration (GO:0014812)3.01059986
54cytoskeletal anchoring at plasma membrane (GO:0007016)2.97950681
55regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.96909324
56collagen metabolic process (GO:0032963)2.95433579
57protein localization to endosome (GO:0036010)2.94369754
58regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.93451571
59negative regulation of anoikis (GO:2000811)2.92657893
60collagen catabolic process (GO:0030574)2.91961823
61regulation of interferon-beta biosynthetic process (GO:0045357)2.90438127
62vascular endothelial growth factor signaling pathway (GO:0038084)2.90288334
63extracellular matrix disassembly (GO:0022617)2.86878076
64cellular response to vitamin (GO:0071295)2.86630751
65substrate adhesion-dependent cell spreading (GO:0034446)2.86543835
66protein hydroxylation (GO:0018126)2.86249273
67planar cell polarity pathway involved in neural tube closure (GO:0090179)2.84884896
68positive regulation of p38MAPK cascade (GO:1900745)2.84047261
69bone trabecula formation (GO:0060346)2.84006835
70glomerular epithelial cell development (GO:0072310)2.82489689
71vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.81899176
72extracellular matrix assembly (GO:0085029)2.81181729
73regulation of early endosome to late endosome transport (GO:2000641)2.81114470
74response to laminar fluid shear stress (GO:0034616)2.79275136
75endocardial cushion development (GO:0003197)2.78846873
76regulation of membrane protein ectodomain proteolysis (GO:0051043)2.78482500
77regulation of mononuclear cell migration (GO:0071675)2.76761919
78stress fiber assembly (GO:0043149)2.76221748
79COPII vesicle coating (GO:0048208)2.75538710
80multicellular organismal macromolecule metabolic process (GO:0044259)2.75186154
81dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.75167986
82hippo signaling (GO:0035329)2.74644119
83actin filament depolymerization (GO:0030042)2.74379794
84positive regulation of extracellular matrix organization (GO:1903055)2.73753662
85protein localization to cell surface (GO:0034394)2.73690606
86low-density lipoprotein particle clearance (GO:0034383)2.73450791
87positive regulation of osteoblast proliferation (GO:0033690)2.73014011
88cellular response to vitamin D (GO:0071305)2.72977650
89heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.72458574
90regulation of transforming growth factor beta1 production (GO:0032908)2.72167186
91positive regulation of interferon-alpha production (GO:0032727)2.72000819
92response to fluid shear stress (GO:0034405)2.71810227
93renal filtration (GO:0097205)2.69831937
94regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.68539090
95vesicle coating (GO:0006901)2.68172169
96retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.68101483
97cell migration involved in heart development (GO:0060973)2.67352112
98multicellular organismal catabolic process (GO:0044243)2.66735733
99metanephric mesenchyme development (GO:0072075)2.66346563
100integrin-mediated signaling pathway (GO:0007229)2.65998164
101hyaluronan catabolic process (GO:0030214)2.65063374
102chondrocyte development (GO:0002063)2.64741437
103positive regulation of receptor recycling (GO:0001921)2.63842121
104response to interferon-alpha (GO:0035455)2.63775489
105membrane raft organization (GO:0031579)2.63686361
106negative regulation of stem cell proliferation (GO:2000647)2.61028141
107branching involved in mammary gland duct morphogenesis (GO:0060444)2.60104288
108negative regulation of keratinocyte proliferation (GO:0010839)2.59953904
109glomerular basement membrane development (GO:0032836)2.58158624
110multicellular organismal metabolic process (GO:0044236)2.57526760
111negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.57477325
112extracellular matrix organization (GO:0030198)2.57131586
113regulation of apoptotic process involved in morphogenesis (GO:1902337)2.56875963
114mesenchymal-epithelial cell signaling (GO:0060638)2.56872992
115extracellular structure organization (GO:0043062)2.56116340
116peptidyl-proline hydroxylation (GO:0019511)2.55940321
117extracellular fibril organization (GO:0043206)2.55780694
118semaphorin-plexin signaling pathway (GO:0071526)2.55662808
119cortical actin cytoskeleton organization (GO:0030866)2.55066336
120regulation of interferon-alpha production (GO:0032647)2.52698435
121positive regulation of cell adhesion mediated by integrin (GO:0033630)2.51695544
122fibroblast migration (GO:0010761)2.51630202
123regulation of anoikis (GO:2000209)2.51487625
124activation of Rac GTPase activity (GO:0032863)2.51328889
125positive regulation of endothelial cell migration (GO:0010595)2.51071994
126macrophage activation involved in immune response (GO:0002281)2.51006686
127regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.50321383
128cell junction assembly (GO:0034329)2.50084068
129myeloid cell homeostasis (GO:0002262)2.48805652
130positive regulation of bone resorption (GO:0045780)2.48200671
131positive regulation of bone remodeling (GO:0046852)2.48200671
132regulation of podosome assembly (GO:0071801)2.47119276
133platelet aggregation (GO:0070527)2.46250018
134positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.45875685
135retina vasculature morphogenesis in camera-type eye (GO:0061299)2.45267851
136heterotypic cell-cell adhesion (GO:0034113)2.45110126
137regulation of macrophage cytokine production (GO:0010935)2.44322993
138regulation of integrin-mediated signaling pathway (GO:2001044)2.43791257
139germ cell migration (GO:0008354)2.43772054
140heterochromatin organization (GO:0070828)2.43632221
141positive regulation of natural killer cell differentiation (GO:0032825)2.43436509
142adherens junction assembly (GO:0034333)2.40200066
143regulation of SMAD protein import into nucleus (GO:0060390)2.39935620
144sequestering of extracellular ligand from receptor (GO:0035581)2.39341103
145cell migration involved in sprouting angiogenesis (GO:0002042)2.38942774
146negative regulation of smooth muscle cell migration (GO:0014912)2.35772672
147hepatocyte apoptotic process (GO:0097284)2.35519476
148endothelial cell morphogenesis (GO:0001886)2.35474604
149regulation of cholesterol storage (GO:0010885)2.33433054
150regulation of tight junction assembly (GO:2000810)2.32490942
151positive regulation of macrophage cytokine production (GO:0060907)2.32478000
152mRNA transcription (GO:0009299)2.31178917
153growth hormone receptor signaling pathway (GO:0060396)2.30415136

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.70880788
2RARG_19884340_ChIP-ChIP_MEFs_Mouse3.98740417
3TRIM28_21343339_ChIP-Seq_HEK293_Human3.97000607
4NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.93675435
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.77473027
6TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.21806742
7SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.82340912
8IRF8_21731497_ChIP-ChIP_J774_Mouse2.68791533
9IRF8_22096565_ChIP-ChIP_GC-B_Human2.64904980
10FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.54506199
11* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.51676657
12CLOCK_20551151_ChIP-Seq_293T_Human2.45645749
13* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.43988338
14RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.43482178
15SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.29776238
16SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.29776238
17* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.29142644
18ZNF263_19887448_ChIP-Seq_K562_Human2.28673825
19CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.27608561
20NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.21816748
21IRF8_27001747_Chip-Seq_BMDM_Mouse2.16627355
22SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.16203133
23MYB_21317192_ChIP-Seq_ERMYB_Mouse2.11592004
24STAT6_21828071_ChIP-Seq_BEAS2B_Human2.07492358
25HIF1A_21447827_ChIP-Seq_MCF-7_Human2.00912965
26* CJUN_26792858_Chip-Seq_BT549_Human1.97806201
27SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.93181716
28ESR1_21235772_ChIP-Seq_MCF-7_Human1.92598982
29PPAR_26484153_Chip-Seq_NCI-H1993_Human1.89229058
30CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.88632581
31* BRD4_25478319_ChIP-Seq_HGPS_Human1.86688153
32ELK3_25401928_ChIP-Seq_HUVEC_Human1.84983898
33FOXO3_23340844_ChIP-Seq_DLD1_Human1.79337254
34* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.77674987
35BP1_19119308_ChIP-ChIP_Hs578T_Human1.71891923
36CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.68416589
37GATA2_21666600_ChIP-Seq_HMVEC_Human1.66206573
38BRD4_27068464_Chip-Seq_AML-cells_Mouse1.64268191
39ESR1_20079471_ChIP-ChIP_T-47D_Human1.62646690
40ATF3_27146783_Chip-Seq_COLON_Human1.59749373
41NRF2_20460467_ChIP-Seq_MEFs_Mouse1.59651607
42NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.59651607
43* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.56051290
44ESR2_21235772_ChIP-Seq_MCF-7_Human1.55859794
45SOX2_20726797_ChIP-Seq_SW620_Human1.53045558
46* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.51569025
47P300_27058665_Chip-Seq_ZR-75-30cells_Human1.50991274
48FOXM1_23109430_ChIP-Seq_U2OS_Human1.49921499
49STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.48913815
50STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.48896666
51UBF1/2_26484160_Chip-Seq_HMECs_Human1.46748673
52NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.43243688
53JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.42666596
54KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.42321654
55STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.40020579
56MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.39945623
57PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.37115723
58* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.36659980
59SALL4_18804426_ChIP-ChIP_XEN_Mouse1.36012335
60WT1_19549856_ChIP-ChIP_CCG9911_Human1.35492021
61UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.33790353
62ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.33658766
63ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.32767811
64TBX20_22080862_ChIP-Seq_HEART_Mouse1.29716474
65TBX20_22328084_ChIP-Seq_HEART_Mouse1.29716474
66TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.27779783
67* AHR_22903824_ChIP-Seq_MCF-7_Human1.26780271
68* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.24163439
69* RACK7_27058665_Chip-Seq_MCF-7_Human1.22866331
70KDM2B_26808549_Chip-Seq_SUP-B15_Human1.22761390
71ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.21576829
72ESR1_15608294_ChIP-ChIP_MCF-7_Human1.20654054
73WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.20016437
74TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.17976571
75IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.17391689
76* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.16498323
77* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.16024053
78TFEB_21752829_ChIP-Seq_HELA_Human1.14726348
79NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.14692080
80TP53_16413492_ChIP-PET_HCT116_Human1.14668289
81KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.12614739
82NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.12373578
83NFIB_24661679_ChIP-Seq_LUNG_Mouse1.11463908
84DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.10560810
85FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.10552269
86VDR_24787735_ChIP-Seq_THP-1_Human1.10099711
87TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.09684311
88* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.09367848
89ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.09039741
90KLF5_25053715_ChIP-Seq_YYC3_Human1.08922073
91VDR_24763502_ChIP-Seq_THP-1_Human1.08472823
92CTNNB1_20460455_ChIP-Seq_HCT116_Human1.07730270
93TCF7_22412390_ChIP-Seq_EML_Mouse1.07409410
94SPI1_23127762_ChIP-Seq_K562_Human1.06997119
95EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.06735486
96KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.06711254
97PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06589773
98TP53_23651856_ChIP-Seq_MEFs_Mouse1.06267831
99STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.05192336
100TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.05022089
101POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.04809529
102NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.03548730
103SMAD_19615063_ChIP-ChIP_OVARY_Human1.02957722
104EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.02387972
105AR_21909140_ChIP-Seq_LNCAP_Human1.01857489
106PU_27001747_Chip-Seq_BMDM_Mouse0.99844272
107MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.99357785
108TP53_22127205_ChIP-Seq_IMR90_Human0.99346344
109CDX2_20551321_ChIP-Seq_CACO-2_Human0.99346111
110ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.98856764
111ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.98794310
112NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.98770233
113EP300_21415370_ChIP-Seq_HL-1_Mouse0.98495707
114VDR_21846776_ChIP-Seq_THP-1_Human0.98487977
115KDM2B_26808549_Chip-Seq_DND41_Human0.97924835
116HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.97923568
117* SMC1_22415368_ChIP-Seq_MEFs_Mouse0.97848613
118* GATA6_25053715_ChIP-Seq_YYC3_Human0.97377730
119NCOR1_26117541_ChIP-Seq_K562_Human0.96920789
120* RUNX1_27514584_Chip-Seq_MCF-7_Human0.95347493
121* TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.94722603
122TP63_23658742_ChIP-Seq_EP156T_Human0.94100909
123CDX2_19796622_ChIP-Seq_MESCs_Mouse0.94070773
124TP53_18474530_ChIP-ChIP_U2OS_Human0.92816625
125DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.91098217
126SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.90742843
127KDM2B_26808549_Chip-Seq_K562_Human0.89667624
128THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.89526866
129* GATA3_24758297_ChIP-Seq_MCF-7_Human0.89505342
130KLF4_18555785_ChIP-Seq_MESCs_Mouse0.88595588
131* ARNT_22903824_ChIP-Seq_MCF-7_Human0.88407176

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.44512337
2MP0003705_abnormal_hypodermis_morpholog4.03380673
3MP0005275_abnormal_skin_tensile3.44909866
4MP0010352_gastrointestinal_tract_polyps3.02936513
5MP0003566_abnormal_cell_adhesion2.92333108
6MP0001958_emphysema2.75764384
7MP0005623_abnormal_meninges_morphology2.50541380
8MP0003279_aneurysm2.43688530
9MP0005257_abnormal_intraocular_pressure2.35662173
10MP0000569_abnormal_digit_pigmentation2.32357693
11MP0005503_abnormal_tendon_morphology2.29653456
12MP0003091_abnormal_cell_migration2.28884338
13MP0003941_abnormal_skin_development2.24717804
14MP0002877_abnormal_melanocyte_morpholog2.21513336
15MP0004272_abnormal_basement_membrane2.14948191
16MP0005023_abnormal_wound_healing2.11569564
17MP0003300_gastrointestinal_ulcer2.02246874
18MP0003191_abnormal_cellular_cholesterol2.02008760
19MP0003303_peritoneal_inflammation2.00557795
20MP0005076_abnormal_cell_differentiation1.93074781
21MP0005058_abnormal_lysosome_morphology1.89391321
22MP0009780_abnormal_chondrocyte_physiolo1.86141266
23MP0002060_abnormal_skin_morphology1.78698194
24MP0006054_spinal_hemorrhage1.70580272
25* MP0000733_abnormal_muscle_development1.56831186
26MP0003436_decreased_susceptibility_to1.50626757
27MP0000762_abnormal_tongue_morphology1.49533771
28MP0003448_altered_tumor_morphology1.48259163
29MP0002796_impaired_skin_barrier1.44186973
30MP0004233_abnormal_muscle_weight1.43745427
31MP0009278_abnormal_bone_marrow1.43085175
32MP0010307_abnormal_tumor_latency1.40743950
33MP0004947_skin_inflammation1.39924280
34MP0003045_fibrosis1.38140568
35MP0000858_altered_metastatic_potential1.37976744
36MP0003453_abnormal_keratinocyte_physiol1.36826255
37MP0010234_abnormal_vibrissa_follicle1.35929721
38MP0000767_abnormal_smooth_muscle1.34509067
39MP0009384_cardiac_valve_regurgitation1.32430623
40MP0000751_myopathy1.30416238
41MP0005508_abnormal_skeleton_morphology1.30406629
42MP0000013_abnormal_adipose_tissue1.28034268
43MP0001533_abnormal_skeleton_physiology1.27808554
44MP0002998_abnormal_bone_remodeling1.27359961
45MP0001243_abnormal_dermal_layer1.25841212
46MP0000467_abnormal_esophagus_morphology1.20963406
47MP0002168_other_aberrant_phenotype1.20844458
48MP0001849_ear_inflammation1.19640227
49MP0000579_abnormal_nail_morphology1.18094782
50MP0002896_abnormal_bone_mineralization1.17299890
51MP0005390_skeleton_phenotype1.14246054
52MP0009840_abnormal_foam_cell1.11858586
53MP0002295_abnormal_pulmonary_circulatio1.11781439
54MP0010030_abnormal_orbit_morphology1.11505086
55MP0005409_darkened_coat_color1.10664140
56MP0003172_abnormal_lysosome_physiology1.08798500
57MP0004858_abnormal_nervous_system1.08044874
58MP0005595_abnormal_vascular_smooth1.07394173
59MP0002419_abnormal_innate_immunity1.05375159
60MP0002933_joint_inflammation1.04686130
61MP0006082_CNS_inflammation1.04021036
62MP0005165_increased_susceptibility_to1.01189678
63MP0001915_intracranial_hemorrhage1.00118967
64MP0000003_abnormal_adipose_tissue0.99418532
65MP0001299_abnormal_eye_distance/0.98383375
66MP0000750_abnormal_muscle_regeneration0.96886742
67MP0001835_abnormal_antigen_presentation0.95889069
68MP0000685_abnormal_immune_system0.95673405
69MP0009053_abnormal_anal_canal0.94204418
70MP0004185_abnormal_adipocyte_glucose0.93559194
71MP0004808_abnormal_hematopoietic_stem0.92473661
72MP0001542_abnormal_bone_strength0.92176484
73MP0005197_abnormal_uvea_morphology0.92082495
74MP0005164_abnormal_response_to0.91181158
75MP0000343_altered_response_to0.90060745
76MP0010678_abnormal_skin_adnexa0.89031628
77MP0010771_integument_phenotype0.88726197
78MP0000627_abnormal_mammary_gland0.88369119
79MP0000537_abnormal_urethra_morphology0.86984555
80MP0009250_abnormal_appendicular_skeleto0.86918018
81MP0003795_abnormal_bone_structure0.86574598
82MP0000428_abnormal_craniofacial_morphol0.85628467
83MP0002282_abnormal_trachea_morphology0.85393296
84MP0003115_abnormal_respiratory_system0.84604556
85MP0008004_abnormal_stomach_pH0.84029351
86MP0001614_abnormal_blood_vessel0.83925069
87MP0005397_hematopoietic_system_phenotyp0.83716855
88MP0001545_abnormal_hematopoietic_system0.83716855
89MP0001879_abnormal_lymphatic_vessel0.83391477
90MP0010368_abnormal_lymphatic_system0.82703211
91MP0005000_abnormal_immune_tolerance0.81560966
92MP0002113_abnormal_skeleton_development0.81454274
93MP0002108_abnormal_muscle_morphology0.80278466
94MP0002166_altered_tumor_susceptibility0.79488566
95MP0002115_abnormal_skeleton_extremities0.79443399
96MP0005464_abnormal_platelet_physiology0.79251134
97MP0001348_abnormal_lacrimal_gland0.78412581
98MP0002452_abnormal_antigen_presenting0.77978588
99MP0000516_abnormal_urinary_system0.77732725
100MP0005367_renal/urinary_system_phenotyp0.77732725
101MP0005451_abnormal_body_composition0.76576721
102MP0001790_abnormal_immune_system0.76262625
103MP0005387_immune_system_phenotype0.76262625
104MP0002128_abnormal_blood_circulation0.75006542
105MP0005193_abnormal_anterior_eye0.74774552
106MP0001216_abnormal_epidermal_layer0.74403930
107MP0002405_respiratory_system_inflammati0.74167496
108MP0002925_abnormal_cardiovascular_devel0.74005533
109MP0002006_tumorigenesis0.73905706
110MP0005621_abnormal_cell_physiology0.73611618
111MP0010386_abnormal_urinary_bladder0.72090953
112MP0000163_abnormal_cartilage_morphology0.71780936
113* MP0000759_abnormal_skeletal_muscle0.71237816
114MP0000432_abnormal_head_morphology0.70707546
115MP0001175_abnormal_lung_morphology0.70646582
116MP0000534_abnormal_ureter_morphology0.70266702
117MP0003942_abnormal_urinary_system0.70237950
118MP0003385_abnormal_body_wall0.69605671
119MP0004883_abnormal_blood_vessel0.68898002
120MP0003950_abnormal_plasma_membrane0.68739245
121MP0002254_reproductive_system_inflammat0.68634453
122MP0004782_abnormal_surfactant_physiolog0.68547703
123MP0003828_pulmonary_edema0.68124707
124MP0005501_abnormal_skin_physiology0.67492535
125MP0003755_abnormal_palate_morphology0.67284944
126MP0001881_abnormal_mammary_gland0.66957372
127MP0002148_abnormal_hypersensitivity_rea0.66783904
128MP0000462_abnormal_digestive_system0.66723811
129MP0009785_altered_susceptibility_to0.66277083
130MP0006138_congestive_heart_failure0.62549472
131MP0002098_abnormal_vibrissa_morphology0.62356135
132MP0000383_abnormal_hair_follicle0.61732599
133MP0004084_abnormal_cardiac_muscle0.61398483
134MP0004264_abnormal_extraembryonic_tissu0.61039653

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)5.60405975
2Protrusio acetabuli (HP:0003179)5.41585892
3Ankle contracture (HP:0006466)4.25228659
4Atrophic scars (HP:0001075)4.04798703
5Cervical subluxation (HP:0003308)4.01587302
6Cerebral aneurysm (HP:0004944)3.90597434
7Shallow orbits (HP:0000586)3.74066857
8Aortic dissection (HP:0002647)3.67162358
9Osteolytic defects of the hand bones (HP:0009699)3.66146097
10Osteolytic defects of the phalanges of the hand (HP:0009771)3.66146097
11Peritonitis (HP:0002586)3.57414408
12Aortic aneurysm (HP:0004942)3.28525835
13Dilatation of the ascending aorta (HP:0005111)3.12679452
14Increased density of long bones (HP:0006392)3.04839580
15Increased connective tissue (HP:0009025)3.03216552
16Fragile skin (HP:0001030)3.00280854
17Vertebral compression fractures (HP:0002953)2.98672221
18Soft skin (HP:0000977)2.83805561
19Ulnar bowing (HP:0003031)2.83064747
20Short nail (HP:0001799)2.81404029
21Mitral valve prolapse (HP:0001634)2.80179350
22Wrist flexion contracture (HP:0001239)2.70598462
23Wormian bones (HP:0002645)2.66086535
24Genu recurvatum (HP:0002816)2.65042811
25Radial bowing (HP:0002986)2.59066147
26Spinal cord lesions (HP:0100561)2.56841393
27Syringomyelia (HP:0003396)2.56841393
28Natal tooth (HP:0000695)2.54751416
29Absent frontal sinuses (HP:0002688)2.53635072
30Spinal rigidity (HP:0003306)2.50613978
31Increased cerebral lipofuscin (HP:0011813)2.45780885
32Mitral stenosis (HP:0001718)2.45675598
33Aortic regurgitation (HP:0001659)2.44142176
34Myocardial infarction (HP:0001658)2.41651855
35Blue sclerae (HP:0000592)2.41277027
36Broad metatarsal (HP:0001783)2.37220031
37Vascular tortuosity (HP:0004948)2.34838849
38Cardiovascular calcification (HP:0011915)2.34707482
39Interstitial pulmonary disease (HP:0006530)2.33622289
40Distal lower limb amyotrophy (HP:0008944)2.31807738
41Distal upper limb amyotrophy (HP:0007149)2.30841078
42Upper limb amyotrophy (HP:0009129)2.30841078
43Bladder diverticulum (HP:0000015)2.30763261
44Neonatal short-limb short stature (HP:0008921)2.30134033
45Bowed forearm bones (HP:0003956)2.29860749
46Bowing of the arm (HP:0006488)2.29860749
47Distal lower limb muscle weakness (HP:0009053)2.26776407
48Spondylolisthesis (HP:0003302)2.26244394
49Follicular hyperkeratosis (HP:0007502)2.25725938
50Abnormality of dentin (HP:0010299)2.24303142
51Arterial tortuosity (HP:0005116)2.21211728
52Aneurysm (HP:0002617)2.21042345
53Hyperacusis (HP:0010780)2.20608169
54Broad face (HP:0000283)2.18866352
55Reduced subcutaneous adipose tissue (HP:0003758)2.18410402
56Tibial bowing (HP:0002982)2.18150494
57Thin bony cortex (HP:0002753)2.16119777
58Type 1 muscle fiber predominance (HP:0003803)2.16074739
59Increased mean platelet volume (HP:0011877)2.13693824
60Elbow flexion contracture (HP:0002987)2.13528441
61Hematochezia (HP:0002573)2.11947012
62Overgrowth (HP:0001548)2.09525043
63Abnormality of the acetabulum (HP:0003170)2.07128204
64Thick nail (HP:0001805)2.04921099
65Subacute progressive viral hepatitis (HP:0006572)2.03806429
66Persistence of primary teeth (HP:0006335)2.03510888
67Alopecia of scalp (HP:0002293)2.03474832
68Entropion (HP:0000621)2.01428280
69Fused cervical vertebrae (HP:0002949)2.00476833
70Milia (HP:0001056)2.00345806
71Camptodactyly of toe (HP:0001836)1.99819521
72Eczematoid dermatitis (HP:0000976)1.97115454
73Achilles tendon contracture (HP:0001771)1.96981094
74Abnormality of the calcaneus (HP:0008364)1.96527849
75Aortic valve stenosis (HP:0001650)1.96446689
76Difficulty climbing stairs (HP:0003551)1.96073454
77Biconcave vertebral bodies (HP:0004586)1.95684535
78Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.94335786
79Abnormal ossification of hand bones (HP:0005921)1.94252675
80Femoral bowing (HP:0002980)1.94133301
81Scapular winging (HP:0003691)1.93836359
82Vacuolated lymphocytes (HP:0001922)1.92987517
83Abnormality of carpal bone ossification (HP:0006257)1.92157937
84Abnormal platelet volume (HP:0011876)1.90975482
85Recurrent abscess formation (HP:0002722)1.90968406
86Right ventricular cardiomyopathy (HP:0011663)1.89834416
87Bowel diverticulosis (HP:0005222)1.89713572
88Abnormality of the distal phalanges of the toes (HP:0010182)1.86777712
89Abnormality of the peritoneum (HP:0002585)1.86097251
90Mildly elevated creatine phosphokinase (HP:0008180)1.84162188
91Generalized amyotrophy (HP:0003700)1.83943003
92Increased variability in muscle fiber diameter (HP:0003557)1.83579085
93Joint stiffness (HP:0001387)1.83498915
94Spinal cord compression (HP:0002176)1.82489128
95Focal segmental glomerulosclerosis (HP:0000097)1.82127050
96Hand muscle atrophy (HP:0009130)1.82052425
97Disproportionate tall stature (HP:0001519)1.81924387
98Dysostosis multiplex (HP:0000943)1.79761450
99Hyperextensible skin (HP:0000974)1.79348041
100Abnormality of oral frenula (HP:0000190)1.79229741
101Mitral regurgitation (HP:0001653)1.78466375
102Increased neuronal autofluorescent lipopigment (HP:0002074)1.78100532
103Slender build (HP:0001533)1.78091427
104Advanced eruption of teeth (HP:0006288)1.77553451
105Glucose intolerance (HP:0000833)1.77361397
106Mesomelia (HP:0003027)1.77090995
107Flat acetabular roof (HP:0003180)1.75545956
108Deviation of the hallux (HP:0010051)1.74575788
109Coxa vara (HP:0002812)1.74111083
110Long toe (HP:0010511)1.74054977
111Axonal loss (HP:0003447)1.73751385
112Abnormality of the odontoid process (HP:0003310)1.73355993
113Selective tooth agenesis (HP:0001592)1.73058222
114Onycholysis (HP:0001806)1.72108891
115Lower limb amyotrophy (HP:0007210)1.70366718
116Abnormal delivery (HP:0001787)1.70033691
117Trismus (HP:0000211)1.69777451
118Hallux valgus (HP:0001822)1.69650603
119Ovoid vertebral bodies (HP:0003300)1.69394290
120Joint laxity (HP:0001388)1.68672023
121Vascular calcification (HP:0004934)1.68407921
122Delayed cranial suture closure (HP:0000270)1.68273688
123Abnormality of the Achilles tendon (HP:0005109)1.67699972
124Striae distensae (HP:0001065)1.66725546
125Joint contractures involving the joints of the feet (HP:0100492)1.66570649
126Flexion contracture of toe (HP:0005830)1.66570649
127Abnormality of skeletal muscle fiber size (HP:0012084)1.66501194
128Abnormality of the frontal sinuses (HP:0002687)1.64948852
129Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.64679828

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN4.57897855
2TRIB33.36136608
3EPHA23.29227649
4DDR23.15252891
5MYLK2.77233606
6PKN22.45236454
7PDGFRA2.35918732
8LATS12.23159582
9TRPM72.22477819
10RIPK12.19153345
11ERN12.16426963
12LRRK22.10714349
13BMX2.04544280
14NTRK11.99876271
15PAK41.90913039
16PTK61.81332203
17ERBB41.74146775
18RPS6KA41.73515295
19STK101.73295082
20STK31.66700644
21PTK21.65050647
22PAK21.64991589
23NEK91.62622137
24TGFBR21.59738393
25ICK1.59651358
26SCYL21.53281690
27CDK121.51176405
28MOS1.50306462
29SIK11.48431110
30LMTK21.42994119
31TBK11.39351188
32STK381.39040537
33EEF2K1.36869080
34CAMK1D1.35136805
35FER1.32456597
36PDGFRB1.31170659
37MST1R1.29757815
38NME21.28928728
39MET1.28423682
40MAP3K141.23695152
41TESK11.22638854
42EPHB21.20083158
43EPHB11.19000744
44CDK61.18366042
45SMG11.16413127
46MAP3K121.15321648
47KIT1.14326168
48MST41.08246919
49CDC42BPA1.01910577
50PIM21.01630106
51JAK11.00518633
52JAK31.00267028
53FRK0.96600446
54PRKD20.94615354
55CSK0.94128642
56MAP3K100.92417779
57MTOR0.90164741
58PBK0.89733821
59TYK20.89123367
60DMPK0.88475754
61IKBKB0.88357402
62MAP3K30.87636073
63CDK80.86150545
64ABL20.86096745
65LATS20.86025122
66MELK0.85094093
67MAP3K60.83492698
68CSF1R0.81934877
69CHUK0.80857767
70ERBB30.80624386
71FGR0.78708338
72FGFR10.73139057
73HCK0.71609173
74MAP3K80.69721390
75MAP2K30.69716714
76MAP2K10.69529130
77MAPKAPK30.68113903
78ARAF0.66791153
79RPS6KA20.66598904
80EGFR0.65449385
81PAK30.65284968
82STK38L0.64201970
83ILK0.63556495
84FLT30.63257569
85LIMK10.63115295
86AKT30.62927590
87TGFBR10.62791228
88ABL10.62449510
89PTK2B0.62223575
90BLK0.61918650
91INSR0.60857755
92CAMK1G0.59893918
93PRKG20.57284738
94RPS6KB20.56814767
95TAOK20.55988075
96ROCK10.55654577
97DYRK1B0.55576771
98FGFR30.55386820
99IRAK30.53781036
100RIPK40.53472560
101ZAP700.51069717
102EIF2AK10.50896969
103MAP3K20.50177639
104CAMK2G0.46360446
105MATK0.45739701
106PAK10.45201514
107NUAK10.45076271
108MAPKAPK20.44522418
109ROCK20.43465480
110KSR10.42872721
111SRC0.42806178
112MARK30.39590391
113CDK90.39474962
114PRPF4B0.38681115
115PIM10.37314918
116EPHA30.37175073
117PIK3CG0.36439374
118GSK3A0.36289382
119MAP3K130.35470305
120GRK70.33565944
121KSR20.33489084
122NEK20.32523322
123FGFR40.32422390
124CAMKK10.32286056
125PAK60.32115804
126PRKD10.31710730
127SIK30.31704245
128CAMK2D0.30842712
129DAPK30.30686508
130MAP3K90.30603930
131CAMKK20.29331263
132ALK0.28841801
133TESK20.28105536
134IGF1R0.28035442
135PDPK10.26770927
136CAMK2B0.26416175
137CDK70.25461002

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.89939346
2Bacterial invasion of epithelial cells_Homo sapiens_hsa051002.37714411
3Focal adhesion_Homo sapiens_hsa045102.31495360
4Small cell lung cancer_Homo sapiens_hsa052222.17620861
5Malaria_Homo sapiens_hsa051442.10761017
6Proteoglycans in cancer_Homo sapiens_hsa052052.09060343
7Amoebiasis_Homo sapiens_hsa051462.06530160
8Leishmaniasis_Homo sapiens_hsa051402.02246232
9Adherens junction_Homo sapiens_hsa045201.94052744
10AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.87609572
11Lysosome_Homo sapiens_hsa041421.83372422
12Chronic myeloid leukemia_Homo sapiens_hsa052201.77883139
13Shigellosis_Homo sapiens_hsa051311.77612745
14Leukocyte transendothelial migration_Homo sapiens_hsa046701.75851391
15Bladder cancer_Homo sapiens_hsa052191.71481481
16Phagosome_Homo sapiens_hsa041451.66684778
17Glycosaminoglycan degradation_Homo sapiens_hsa005311.63630423
18Toxoplasmosis_Homo sapiens_hsa051451.63501883
19Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.63139422
20Osteoclast differentiation_Homo sapiens_hsa043801.58367159
21Salmonella infection_Homo sapiens_hsa051321.57147975
22MicroRNAs in cancer_Homo sapiens_hsa052061.55230170
23Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.50700054
24Toll-like receptor signaling pathway_Homo sapiens_hsa046201.50416322
25TNF signaling pathway_Homo sapiens_hsa046681.50378007
26Tuberculosis_Homo sapiens_hsa051521.45298705
27Regulation of actin cytoskeleton_Homo sapiens_hsa048101.45039298
28Pertussis_Homo sapiens_hsa051331.43159087
29Apoptosis_Homo sapiens_hsa042101.41022546
30Pancreatic cancer_Homo sapiens_hsa052121.35262967
31Viral myocarditis_Homo sapiens_hsa054161.35132060
32Legionellosis_Homo sapiens_hsa051341.33317579
33NF-kappa B signaling pathway_Homo sapiens_hsa040641.28222718
34Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.23720891
35Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.22871584
36Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.20192557
37Platelet activation_Homo sapiens_hsa046111.18908308
38p53 signaling pathway_Homo sapiens_hsa041151.16270073
39TGF-beta signaling pathway_Homo sapiens_hsa043501.14237426
40Vibrio cholerae infection_Homo sapiens_hsa051101.11147521
41Galactose metabolism_Homo sapiens_hsa000521.09599941
42Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.08924440
43Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.08670080
44Other glycan degradation_Homo sapiens_hsa005111.08631996
45Hepatitis B_Homo sapiens_hsa051611.07094612
46Rheumatoid arthritis_Homo sapiens_hsa053231.06824412
47Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.06450644
48Hematopoietic cell lineage_Homo sapiens_hsa046401.05521700
49PI3K-Akt signaling pathway_Homo sapiens_hsa041511.04297059
50Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.03297560
51Hippo signaling pathway_Homo sapiens_hsa043901.02778411
52Melanoma_Homo sapiens_hsa052181.02686213
53Staphylococcus aureus infection_Homo sapiens_hsa051501.01900046
54Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.01081294
55NOD-like receptor signaling pathway_Homo sapiens_hsa046211.00702033
56Measles_Homo sapiens_hsa051620.98827981
57Prion diseases_Homo sapiens_hsa050200.95905423
58B cell receptor signaling pathway_Homo sapiens_hsa046620.95040882
59Viral carcinogenesis_Homo sapiens_hsa052030.94343787
60Antigen processing and presentation_Homo sapiens_hsa046120.94301989
61Glioma_Homo sapiens_hsa052140.90303332
62Caffeine metabolism_Homo sapiens_hsa002320.89448471
63Thyroid hormone signaling pathway_Homo sapiens_hsa049190.89157460
64N-Glycan biosynthesis_Homo sapiens_hsa005100.89089268
65Dilated cardiomyopathy_Homo sapiens_hsa054140.89038980
66Prostate cancer_Homo sapiens_hsa052150.88351113
67Pentose phosphate pathway_Homo sapiens_hsa000300.88087643
68Influenza A_Homo sapiens_hsa051640.87801425
69Acute myeloid leukemia_Homo sapiens_hsa052210.86115011
70Sphingolipid metabolism_Homo sapiens_hsa006000.85016001
71Tight junction_Homo sapiens_hsa045300.84937602
72Axon guidance_Homo sapiens_hsa043600.84668100
73Pathways in cancer_Homo sapiens_hsa052000.83635649
74Endocytosis_Homo sapiens_hsa041440.81181113
75ErbB signaling pathway_Homo sapiens_hsa040120.80957531
76HTLV-I infection_Homo sapiens_hsa051660.80850313
77Jak-STAT signaling pathway_Homo sapiens_hsa046300.80834737
78Protein digestion and absorption_Homo sapiens_hsa049740.80019915
79HIF-1 signaling pathway_Homo sapiens_hsa040660.78611880
80Renal cell carcinoma_Homo sapiens_hsa052110.78403860
81Rap1 signaling pathway_Homo sapiens_hsa040150.75882562
82Neurotrophin signaling pathway_Homo sapiens_hsa047220.75525004
83mTOR signaling pathway_Homo sapiens_hsa041500.74080745
84Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.72874416
85VEGF signaling pathway_Homo sapiens_hsa043700.72855581
86Hepatitis C_Homo sapiens_hsa051600.72236163
87Renin-angiotensin system_Homo sapiens_hsa046140.71581145
88Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.71166642
89Basal cell carcinoma_Homo sapiens_hsa052170.70852905
90RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.70040119
91Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.70037628
92Central carbon metabolism in cancer_Homo sapiens_hsa052300.68509738
93Colorectal cancer_Homo sapiens_hsa052100.67502952
94Gap junction_Homo sapiens_hsa045400.67355428
95Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.65330215
96Endometrial cancer_Homo sapiens_hsa052130.65170345
97Melanogenesis_Homo sapiens_hsa049160.64566753
98Prolactin signaling pathway_Homo sapiens_hsa049170.63535742
99Phospholipase D signaling pathway_Homo sapiens_hsa040720.63299081
100Estrogen signaling pathway_Homo sapiens_hsa049150.62733157
101Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.62484764
102Non-small cell lung cancer_Homo sapiens_hsa052230.62394405
103Sulfur metabolism_Homo sapiens_hsa009200.61918879
104Hedgehog signaling pathway_Homo sapiens_hsa043400.61622506
105Notch signaling pathway_Homo sapiens_hsa043300.61575852
106Chemokine signaling pathway_Homo sapiens_hsa040620.61358770
107Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.60859803
108Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.60263000
109Herpes simplex infection_Homo sapiens_hsa051680.59062385
110Thyroid cancer_Homo sapiens_hsa052160.58190105
111Transcriptional misregulation in cancer_Homo sapiens_hsa052020.56583483
112GnRH signaling pathway_Homo sapiens_hsa049120.55870138
113Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.55675280
114Fructose and mannose metabolism_Homo sapiens_hsa000510.55392899
115Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.55048467
116Insulin signaling pathway_Homo sapiens_hsa049100.53778299
117Adipocytokine signaling pathway_Homo sapiens_hsa049200.52333508
118FoxO signaling pathway_Homo sapiens_hsa040680.51198204
119Complement and coagulation cascades_Homo sapiens_hsa046100.49693673
120Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.49370351
121Inositol phosphate metabolism_Homo sapiens_hsa005620.48617423
122Wnt signaling pathway_Homo sapiens_hsa043100.47666808
123Insulin resistance_Homo sapiens_hsa049310.47592725
124Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.47449474
125Sphingolipid signaling pathway_Homo sapiens_hsa040710.44728931
126Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.44164426
127Mineral absorption_Homo sapiens_hsa049780.42907663
128Thyroid hormone synthesis_Homo sapiens_hsa049180.42427924
129AMPK signaling pathway_Homo sapiens_hsa041520.40543131
130Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.39921963

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