MYOG

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* muscle cell fate commitment (GO:0042693)9.53607493
2actin-mediated cell contraction (GO:0070252)9.48987617
3plasma membrane repair (GO:0001778)9.20393566
4positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)9.03125651
5* myotube cell development (GO:0014904)8.98417051
6* positive regulation of myotube differentiation (GO:0010831)8.62971558
7myotube differentiation (GO:0014902)8.57947933
8myoblast fusion (GO:0007520)8.55543579
9syncytium formation by plasma membrane fusion (GO:0000768)7.76392476
10muscle cell cellular homeostasis (GO:0046716)7.75602677
11sarcomere organization (GO:0045214)7.23881331
12actin filament-based movement (GO:0030048)7.18437673
13syncytium formation (GO:0006949)7.15462228
14negative regulation of potassium ion transmembrane transporter activity (GO:1901017)7.00827233
15* regulation of syncytium formation by plasma membrane fusion (GO:0060142)6.51573392
16striated muscle contraction (GO:0006941)6.37063960
17neuromuscular synaptic transmission (GO:0007274)6.15160096
18regulation of skeletal muscle contraction (GO:0014819)6.10032591
19muscle organ development (GO:0007517)5.58590878
20* muscle fiber development (GO:0048747)5.51983268
21negative regulation of potassium ion transmembrane transport (GO:1901380)5.44503396
22sarcoplasmic reticulum calcium ion transport (GO:0070296)5.43896588
23muscle structure development (GO:0061061)5.43396032
24* skeletal muscle tissue development (GO:0007519)5.08318192
25* response to muscle activity (GO:0014850)5.00027195
26actomyosin structure organization (GO:0031032)4.98561800
27regulation of relaxation of muscle (GO:1901077)4.80132690
28regulation of sarcomere organization (GO:0060297)4.79339311
29* response to inactivity (GO:0014854)4.78977291
30neuromuscular junction development (GO:0007528)4.77525843
31negative regulation of gluconeogenesis (GO:0045721)4.75089514
32plasma membrane fusion (GO:0045026)4.74655765
33muscle contraction (GO:0006936)4.74442149
34* response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.57465540
35negative regulation of nitric-oxide synthase activity (GO:0051001)4.49504535
36negative regulation of cell size (GO:0045792)4.43926849
37embryonic camera-type eye development (GO:0031076)4.42018318
38regulation of protein heterodimerization activity (GO:0043497)4.31539943
39* positive regulation of muscle cell differentiation (GO:0051149)4.28910160
40face morphogenesis (GO:0060325)4.18469291
41* striated muscle cell development (GO:0055002)4.15746632
42* muscle system process (GO:0003012)4.10460283
43negative regulation of muscle hypertrophy (GO:0014741)4.09550992
44* positive regulation of striated muscle cell differentiation (GO:0051155)4.06472956
45embryonic retina morphogenesis in camera-type eye (GO:0060059)4.02870303
46* regulation of myotube differentiation (GO:0010830)4.01876728
47positive regulation of protein depolymerization (GO:1901881)4.01302869
48epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)3.96863309
49regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.93329464
50* muscle cell development (GO:0055001)3.87108654
51* positive regulation of skeletal muscle tissue development (GO:0048643)3.85841253
52regulation of skeletal muscle cell differentiation (GO:2001014)3.78670949
53negative regulation of cardiac muscle tissue development (GO:0055026)3.74798068
54* cellular response to estradiol stimulus (GO:0071392)3.74747028
55myofibril assembly (GO:0030239)3.72777804
56regulation of actin filament-based movement (GO:1903115)3.69807531
57regulation of alkaline phosphatase activity (GO:0010692)3.65648113
58muscle tissue morphogenesis (GO:0060415)3.53244769
59cardiac myofibril assembly (GO:0055003)3.53186464
60regulation of p38MAPK cascade (GO:1900744)3.49858993
61postsynaptic membrane organization (GO:0001941)3.49023417
62regulation of action potential (GO:0098900)3.48443675
63skeletal muscle cell differentiation (GO:0035914)3.45379924
64behavioral response to nicotine (GO:0035095)3.45012316
65synaptic transmission, cholinergic (GO:0007271)3.41404972
66* striated muscle tissue development (GO:0014706)3.38433051
67* regulation of muscle cell differentiation (GO:0051147)3.33975421
68membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.33834641
69embryonic body morphogenesis (GO:0010172)3.33156175
70positive regulation of glycogen biosynthetic process (GO:0045725)3.29302452
71positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.24052577
72neuronal action potential (GO:0019228)3.23117194
73cardiac muscle tissue morphogenesis (GO:0055008)3.21653174
74regulation of muscle contraction (GO:0006937)3.20954692
75body morphogenesis (GO:0010171)3.20352622
76heart contraction (GO:0060047)3.19089765
77heart process (GO:0003015)3.19089765
78cardiac muscle cell development (GO:0055013)3.16075875
79negative regulation of organelle assembly (GO:1902116)3.12307774
80* regulation of muscle system process (GO:0090257)3.11736600
81skeletal muscle tissue regeneration (GO:0043403)3.11544550
82otic vesicle formation (GO:0030916)3.09981223
83cornea development in camera-type eye (GO:0061303)3.06115966
84organ induction (GO:0001759)3.04713248
85cardiac muscle contraction (GO:0060048)3.03984751
86positive regulation of astrocyte differentiation (GO:0048711)3.02041284
87tooth mineralization (GO:0034505)3.00048363
88regulation of striated muscle contraction (GO:0006942)2.98538305
89* muscle tissue development (GO:0060537)2.97544421
90response to gravity (GO:0009629)2.97498939
91response to caffeine (GO:0031000)2.94461754
92glucan biosynthetic process (GO:0009250)2.94322271
93glycogen biosynthetic process (GO:0005978)2.94322271
94regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.92913832
95* positive regulation of myoblast differentiation (GO:0045663)2.92688267
96creatine metabolic process (GO:0006600)2.91638216
97* regulation of myoblast differentiation (GO:0045661)2.90977402
98negative regulation of protein localization to cell surface (GO:2000009)2.90735590
99replacement ossification (GO:0036075)2.90651918
100endochondral ossification (GO:0001958)2.90651918
101positive regulation of protein complex disassembly (GO:0043243)2.89589638
102regulation of membrane repolarization (GO:0060306)2.88766965
103* regulation of striated muscle cell differentiation (GO:0051153)2.88472900
104cardiac cell development (GO:0055006)2.88304527
105skeletal muscle adaptation (GO:0043501)2.88136619
106* striated muscle adaptation (GO:0014888)2.88044073
107negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.87450964
108outer ear morphogenesis (GO:0042473)2.86854911
109negative regulation of cardiac muscle hypertrophy (GO:0010614)2.86807673
110regulation of cell communication by electrical coupling (GO:0010649)2.86154606
111regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.85566996
112* striated muscle atrophy (GO:0014891)2.84743580
113* muscle cell differentiation (GO:0042692)2.84569473
114regulation of potassium ion transmembrane transport (GO:1901379)2.84189493
115positive regulation of glycogen metabolic process (GO:0070875)2.82646343
116negative regulation of fatty acid transport (GO:2000192)2.78652728
117cellular response to glucocorticoid stimulus (GO:0071385)2.74371363
118positive regulation of protein homodimerization activity (GO:0090073)2.73468877
119regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.69960701
120striated muscle cell differentiation (GO:0051146)2.67782948
121cellular response to corticosteroid stimulus (GO:0071384)2.65560159
122negative regulation of potassium ion transport (GO:0043267)2.53661335
123positive regulation of cellular response to insulin stimulus (GO:1900078)2.52471625
124negative regulation of heart growth (GO:0061117)2.52144681
125negative regulation of cardiac muscle tissue growth (GO:0055022)2.52144681
126negative regulation of chondrocyte differentiation (GO:0032331)2.51301316
127regulation of calcium ion transmembrane transporter activity (GO:1901019)2.51152631
128regulation of calcium ion transmembrane transport (GO:1903169)2.51152631
129regulation of potassium ion transmembrane transporter activity (GO:1901016)2.50363105
130embryonic viscerocranium morphogenesis (GO:0048703)2.49056447
131regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.48358447
132regulation of cardiac muscle cell differentiation (GO:2000725)2.45538636
133positive regulation of p38MAPK cascade (GO:1900745)2.43698192
134skeletal muscle contraction (GO:0003009)13.7877080
135muscle filament sliding (GO:0030049)11.3790248
136actin-myosin filament sliding (GO:0033275)11.3790248
137* skeletal muscle fiber development (GO:0048741)10.7420986
138musculoskeletal movement (GO:0050881)10.1724106
139multicellular organismal movement (GO:0050879)10.1724106

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human5.30418068
2EZH2_22144423_ChIP-Seq_EOC_Human4.38622691
3TP63_17297297_ChIP-ChIP_HaCaT_Human4.01348972
4RARG_19884340_ChIP-ChIP_MEFs_Mouse3.39383952
5ESR1_21235772_ChIP-Seq_MCF-7_Human2.92027581
6WT1_19549856_ChIP-ChIP_CCG9911_Human2.89325933
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.77935755
8TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.64065558
9RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.61691888
10MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.54697368
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.40766695
12ESR2_21235772_ChIP-Seq_MCF-7_Human2.39877936
13CLOCK_20551151_ChIP-Seq_293T_Human2.27583358
14WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.21209604
15EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.20478878
16TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.18731986
17ERG_21242973_ChIP-ChIP_JURKAT_Human2.18235047
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.17328095
19BP1_19119308_ChIP-ChIP_Hs578T_Human2.15856790
20ZFP281_18757296_ChIP-ChIP_E14_Mouse2.12950165
21* ESR1_20079471_ChIP-ChIP_T-47D_Human2.08250723
22RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.04488926
23TBX20_22328084_ChIP-Seq_HEART_Mouse2.01644825
24TBX20_22080862_ChIP-Seq_HEART_Mouse2.01644825
25THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.00467518
26IGF1R_20145208_ChIP-Seq_DFB_Human2.00286964
27PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.99688747
28SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.89078324
29JARID2_20064375_ChIP-Seq_MESCs_Mouse1.82731158
30SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.81616904
31SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.80780534
32P300_27058665_Chip-Seq_ZR-75-30cells_Human1.80669334
33ELK3_25401928_ChIP-Seq_HUVEC_Human1.78247835
34PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.76855459
35TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.71690444
36* MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.68947502
37CBX2_27304074_Chip-Seq_ESCs_Mouse1.66912638
38KDM2B_26808549_Chip-Seq_SUP-B15_Human1.65310794
39GBX2_23144817_ChIP-Seq_PC3_Human1.65079753
40ZNF263_19887448_ChIP-Seq_K562_Human1.62743634
41KDM2B_26808549_Chip-Seq_DND41_Human1.61322277
42SUZ12_27294783_Chip-Seq_NPCs_Mouse1.58703546
43PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.57758164
44TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.57137741
45FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.56113428
46SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.53573942
47* LXR_22292898_ChIP-Seq_THP-1_Human1.52803455
48KDM2B_26808549_Chip-Seq_K562_Human1.52341563
49* EZH2_27294783_Chip-Seq_ESCs_Mouse1.49522674
50BMI1_23680149_ChIP-Seq_NPCS_Mouse1.48756761
51KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.48194180
52OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.46898235
53DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.46859190
54EP300_21415370_ChIP-Seq_HL-1_Mouse1.46633099
55ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.41293742
56EZH2_18974828_ChIP-Seq_MESCs_Mouse1.41157617
57RNF2_18974828_ChIP-Seq_MESCs_Mouse1.41157617
58* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.40479051
59SMC1_22415368_ChIP-Seq_MEFs_Mouse1.40002448
60* CRX_20693478_ChIP-Seq_RETINA_Mouse1.39998138
61SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.38445982
62ATF3_27146783_Chip-Seq_COLON_Human1.37593960
63MTF2_20144788_ChIP-Seq_MESCs_Mouse1.36711027
64NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.35238333
65UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.35128649
66TP53_20018659_ChIP-ChIP_R1E_Mouse1.34422267
67TP53_16413492_ChIP-PET_HCT116_Human1.33592544
68GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.32622043
69PPAR_26484153_Chip-Seq_NCI-H1993_Human1.32058486
70CJUN_26792858_Chip-Seq_BT549_Human1.31241111
71PCGF2_27294783_Chip-Seq_NPCs_Mouse1.28805061
72VDR_22108803_ChIP-Seq_LS180_Human1.28268750
73TCF7_22412390_ChIP-Seq_EML_Mouse1.26848983
74TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.26339023
75HIF1A_21447827_ChIP-Seq_MCF-7_Human1.25853095
76* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.25699398
77TP53_22127205_ChIP-Seq_IMR90_Human1.24793182
78CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.24698402
79RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.23578845
80KDM2B_26808549_Chip-Seq_REH_Human1.22699168
81ZNF274_21170338_ChIP-Seq_K562_Hela1.21465678
82TP53_18474530_ChIP-ChIP_U2OS_Human1.19962484
83RING1B_27294783_Chip-Seq_ESCs_Mouse1.19408616
84ZFP57_27257070_Chip-Seq_ESCs_Mouse1.18641630
85* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.17383292
86* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.17130290
87ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.16956972
88KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.16886440
89* RAD21_21589869_ChIP-Seq_MESCs_Mouse1.16446361
90BRD4_25478319_ChIP-Seq_HGPS_Human1.16021673
91* P53_22387025_ChIP-Seq_ESCs_Mouse1.15980870
92* NFE2_27457419_Chip-Seq_LIVER_Mouse1.15777139
93EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.14954678
94TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.14599195
95PKCTHETA_26484144_Chip-Seq_BREAST_Human1.14568098
96SMC3_22415368_ChIP-Seq_MEFs_Mouse1.14465481
97* RACK7_27058665_Chip-Seq_MCF-7_Human1.13544574
98P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12013165
99ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.11905538
100TDRD3_21172665_ChIP-Seq_MCF-7_Human1.11876655
101* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.11470668
102* EZH2_27294783_Chip-Seq_NPCs_Mouse1.10644779
103CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.10543066
104* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.07780165
105KDM2B_26808549_Chip-Seq_JURKAT_Human1.06731572
106* TP53_23651856_ChIP-Seq_MEFs_Mouse1.06718250
107EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.06669654
108GATA1_22025678_ChIP-Seq_K562_Human1.05474744
109DNAJC2_21179169_ChIP-ChIP_NT2_Human1.04749385
110* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.04321670
111ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.03933450
112SA1_27219007_Chip-Seq_Bcells_Human1.03817179
113CTNNB1_20460455_ChIP-Seq_HCT116_Human1.02969807
114HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.02426962
115FUS_26573619_Chip-Seq_HEK293_Human1.02117574
116NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.01988295
117PCGF2_27294783_Chip-Seq_ESCs_Mouse1.01927299
118* OCT4_21477851_ChIP-Seq_ESCs_Mouse1.01365477
119CTCF_27219007_Chip-Seq_Bcells_Human1.01267964
120SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.01193167
121SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.00372960
122* CTCF_21964334_Chip-Seq_Bcells_Human1.00064900
123NFIB_24661679_ChIP-Seq_LUNG_Mouse0.99967749
124NR3C1_23031785_ChIP-Seq_PC12_Mouse0.99754004
125ARNT_22903824_ChIP-Seq_MCF-7_Human0.98654364
126KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.97934352
127KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.97915777
128* ZFX_18555785_Chip-Seq_ESCs_Mouse0.96426325
129RUNX1_27514584_Chip-Seq_MCF-7_Human0.96333017
130DROSHA_22980978_ChIP-Seq_HELA_Human0.96073149
131CREB1_26743006_Chip-Seq_LNCaP_Human0.96024091
132* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.95918122
133SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.95170232
134AHR_22903824_ChIP-Seq_MCF-7_Human0.95147876
135UBF1/2_26484160_Chip-Seq_HMECs_Human0.95106721
136EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.94804536
137* STAT3_18555785_Chip-Seq_ESCs_Mouse0.94430442
138MYC_27129775_Chip-Seq_CORNEA_Mouse0.94383854
139GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93554940
140SOX2_21211035_ChIP-Seq_LN229_Gbm0.92794277
141CDX2_19796622_ChIP-Seq_MESCs_Mouse0.92378933
142* PU1_27457419_Chip-Seq_LIVER_Mouse0.92378709
143TOP2B_26459242_ChIP-Seq_MCF-7_Human0.91565076
144IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.91505719
145CBP_20019798_ChIP-Seq_JUKART_Human0.91505719
146WT1_25993318_ChIP-Seq_PODOCYTE_Human0.91094561
147NR3C1_21868756_ChIP-Seq_MCF10A_Human0.90940026
148GATA1_19941826_ChIP-Seq_K562_Human0.90149775
149RNF2_27304074_Chip-Seq_ESCs_Mouse0.89908364
150EZH2_27304074_Chip-Seq_ESCs_Mouse0.89748573
151TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89042282
152ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.88804716
153* OCT4_18555785_Chip-Seq_ESCs_Mouse0.88331231
154JARID2_20075857_ChIP-Seq_MESCs_Mouse0.88294167
155SOX2_20726797_ChIP-Seq_SW620_Human0.87798967
156ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.86670666
157ZNF217_24962896_ChIP-Seq_MCF-7_Human0.85592141
158STAT6_21828071_ChIP-Seq_BEAS2B_Human0.84528296
159ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.84518919
160STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.84410659

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000750_abnormal_muscle_regeneration6.08967424
2MP0000749_muscle_degeneration5.94163996
3* MP0000733_abnormal_muscle_development5.88451373
4MP0000751_myopathy5.42302223
5MP0000747_muscle_weakness4.73778496
6MP0004145_abnormal_muscle_electrophysio4.03660647
7MP0003646_muscle_fatigue3.91522747
8MP0002106_abnormal_muscle_physiology3.84483624
9MP0009780_abnormal_chondrocyte_physiolo3.66746776
10* MP0000759_abnormal_skeletal_muscle3.58827076
11MP0004087_abnormal_muscle_fiber3.57261252
12MP0005369_muscle_phenotype3.19008012
13MP0002108_abnormal_muscle_morphology2.97445556
14MP0002269_muscular_atrophy2.74892446
15MP0005623_abnormal_meninges_morphology2.67913073
16MP0003950_abnormal_plasma_membrane2.67313382
17* MP0004270_analgesia2.62965148
18MP0004233_abnormal_muscle_weight2.54310984
19MP0002837_dystrophic_cardiac_calcinosis2.34577383
20MP0003941_abnormal_skin_development2.28415055
21MP0004084_abnormal_cardiac_muscle2.25284992
22MP0010030_abnormal_orbit_morphology2.17995028
23MP0001299_abnormal_eye_distance/2.03989270
24MP0005330_cardiomyopathy1.76140228
25MP0002877_abnormal_melanocyte_morpholog1.73210469
26MP0004036_abnormal_muscle_relaxation1.68847315
27MP0004215_abnormal_myocardial_fiber1.64729267
28MP0005620_abnormal_muscle_contractility1.64273690
29MP0008438_abnormal_cutaneous_collagen1.55107559
30MP0010630_abnormal_cardiac_muscle1.47491312
31MP0004134_abnormal_chest_morphology1.45313500
32MP0002332_abnormal_exercise_endurance1.37864319
33MP0003879_abnormal_hair_cell1.35404176
34* MP0002971_abnormal_brown_adipose1.35342764
35MP0001346_abnormal_lacrimal_gland1.26341348
36MP0002972_abnormal_cardiac_muscle1.24808676
37MP0002127_abnormal_cardiovascular_syste1.21523570
38MP0003385_abnormal_body_wall1.18787608
39MP0005503_abnormal_tendon_morphology1.14751565
40MP0005248_abnormal_Harderian_gland1.14164712
41MP0003137_abnormal_impulse_conducting1.12505526
42MP0003705_abnormal_hypodermis_morpholog1.07281156
43MP0000013_abnormal_adipose_tissue1.06887241
44MP0004858_abnormal_nervous_system1.06083536
45* MP0002734_abnormal_mechanical_nocicepti1.04271677
46MP0000049_abnormal_middle_ear1.02953543
47MP0003566_abnormal_cell_adhesion0.98960511
48* MP0002114_abnormal_axial_skeleton0.97491442
49MP0003091_abnormal_cell_migration0.97123995
50MP0002234_abnormal_pharynx_morphology0.96939199
51MP0001661_extended_life_span0.96482739
52MP0003122_maternal_imprinting0.96367525
53MP0009250_abnormal_appendicular_skeleto0.94636957
54MP0000678_abnormal_parathyroid_gland0.94519367
55MP0002184_abnormal_innervation0.91726817
56MP0002932_abnormal_joint_morphology0.85172244
57MP0005451_abnormal_body_composition0.80768032
58MP0003828_pulmonary_edema0.80076205
59MP0003279_aneurysm0.79526830
60MP0004197_abnormal_fetal_growth/weight/0.77558588
61MP0000428_abnormal_craniofacial_morphol0.77299153
62MP0002822_catalepsy0.76364542
63MP0000003_abnormal_adipose_tissue0.76285082
64MP0004130_abnormal_muscle_cell0.75551801
65MP0000516_abnormal_urinary_system0.75512315
66MP0005367_renal/urinary_system_phenotyp0.75512315
67MP0008775_abnormal_heart_ventricle0.75053234
68MP0003755_abnormal_palate_morphology0.75019278
69MP0003942_abnormal_urinary_system0.74749260
70MP0005275_abnormal_skin_tensile0.74159088
71MP0004142_abnormal_muscle_tone0.73827612
72MP0001958_emphysema0.72294253
73MP0002160_abnormal_reproductive_system0.70495038
74MP0006036_abnormal_mitochondrial_physio0.68449346
75MP0004510_myositis0.67540040
76MP0001485_abnormal_pinna_reflex0.66754307
77MP0004272_abnormal_basement_membrane0.65941946
78MP0000955_abnormal_spinal_cord0.65792069
79* MP0001943_abnormal_respiration0.65084666
80MP0005508_abnormal_skeleton_morphology0.64372491
81MP0000767_abnormal_smooth_muscle0.63774447
82MP0003959_abnormal_lean_body0.63614479
83MP0000858_altered_metastatic_potential0.62794804
84MP0005076_abnormal_cell_differentiation0.59280570
85MP0004484_altered_response_of0.59077485
86MP0000762_abnormal_tongue_morphology0.58610368
87MP0005670_abnormal_white_adipose0.56275422
88MP0000467_abnormal_esophagus_morphology0.53731605
89MP0009384_cardiac_valve_regurgitation0.52662832
90* MP0001542_abnormal_bone_strength0.52402907
91MP0002896_abnormal_bone_mineralization0.52400160
92MP0001544_abnormal_cardiovascular_syste0.50946897
93MP0005385_cardiovascular_system_phenoty0.50946897
94* MP0002081_perinatal_lethality0.50347072
95MP0003300_gastrointestinal_ulcer0.49890735
96MP0002089_abnormal_postnatal_growth/wei0.49211174
97MP0000266_abnormal_heart_morphology0.48834308
98MP0002233_abnormal_nose_morphology0.47607527
99MP0005375_adipose_tissue_phenotype0.47500992
100MP0002163_abnormal_gland_morphology0.46686388
101MP0005266_abnormal_metabolism0.45665827
102MP0003011_delayed_dark_adaptation0.45168922
103MP0002128_abnormal_blood_circulation0.44671708
104MP0003567_abnormal_fetal_cardiomyocyte0.44622030
105MP0000372_irregular_coat_pigmentation0.44247540
106MP0001849_ear_inflammation0.43545312
107MP0004085_abnormal_heartbeat0.43143361
108MP0000534_abnormal_ureter_morphology0.43011504
109MP0009379_abnormal_foot_pigmentation0.39985868
110MP0000432_abnormal_head_morphology0.39830867
111MP0008789_abnormal_olfactory_epithelium0.39787323
112MP0006138_congestive_heart_failure0.39204744
113MP0009053_abnormal_anal_canal0.38464101
114MP0003221_abnormal_cardiomyocyte_apopto0.36908029
115MP0004185_abnormal_adipocyte_glucose0.36578747
116MP0000230_abnormal_systemic_arterial0.35801015
117MP0006276_abnormal_autonomic_nervous0.35734331
118MP0003453_abnormal_keratinocyte_physiol0.35259062
119MP0003283_abnormal_digestive_organ0.35136334
120* MP0003948_abnormal_gas_homeostasis0.34967110
121MP0002116_abnormal_craniofacial_bone0.34918049
122MP0001915_intracranial_hemorrhage0.34902623
123MP0005595_abnormal_vascular_smooth0.34048585
124MP0005423_abnormal_somatic_nervous0.33572078
125MP0001440_abnormal_grooming_behavior0.33458326
126MP0005319_abnormal_enzyme/_coenzyme0.32663281
127MP0001348_abnormal_lacrimal_gland0.32642416
128MP0000163_abnormal_cartilage_morphology0.32554912
129MP0003935_abnormal_craniofacial_develop0.31930956
130MP0000537_abnormal_urethra_morphology0.30859958

Predicted human phenotypes

RankGene SetZ-score
1Fetal akinesia sequence (HP:0001989)8.38812822
2Popliteal pterygium (HP:0009756)7.98991237
3Aplasia of the musculature (HP:0100854)7.28191865
4Amniotic constriction ring (HP:0009775)7.03842489
5Abnormality of placental membranes (HP:0011409)7.03842489
6Malignant hyperthermia (HP:0002047)6.90751032
7Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)6.79397121
8Distal arthrogryposis (HP:0005684)6.76785889
9Round ear (HP:0100830)6.73910519
10Ulnar deviation of the wrist (HP:0003049)6.55419476
11Muscle fiber inclusion bodies (HP:0100299)6.25649254
12Type 2 muscle fiber atrophy (HP:0003554)6.21719413
13Akinesia (HP:0002304)6.08075555
14Nemaline bodies (HP:0003798)5.74352073
15Calcaneovalgus deformity (HP:0001848)5.71284422
16Muscle fiber atrophy (HP:0100295)5.63166604
17Abnormality of the neuromuscular junction (HP:0003398)5.37033606
18Fatigable weakness (HP:0003473)5.37033606
19Deformed tarsal bones (HP:0008119)5.18699573
20Type 1 muscle fiber predominance (HP:0003803)5.11234679
21Absent phalangeal crease (HP:0006109)4.88739999
22Weak cry (HP:0001612)4.85271134
23Muscle fiber splitting (HP:0003555)4.61501432
24Exercise-induced muscle cramps (HP:0003710)4.50077479
25Aplasia/Hypoplasia involving the musculature (HP:0001460)4.35805638
26Pterygium (HP:0001059)4.35230683
27Thin ribs (HP:0000883)4.31428798
28Gowers sign (HP:0003391)4.17890265
29Difficulty running (HP:0009046)4.16693011
30Abnormal finger flexion creases (HP:0006143)4.10304387
31Difficulty climbing stairs (HP:0003551)4.10095972
32Breech presentation (HP:0001623)4.09414493
33Chin dimple (HP:0010751)4.05144188
34Bulbar palsy (HP:0001283)4.01301484
35Trismus (HP:0000211)3.95049157
36Hip contracture (HP:0003273)3.94348917
37Easy fatigability (HP:0003388)3.84222709
38Myopathic facies (HP:0002058)3.82577705
39Hypoplastic heart (HP:0001961)3.75568319
40Abnormality of the calcaneus (HP:0008364)3.59195881
41Mildly elevated creatine phosphokinase (HP:0008180)3.56633826
42Abnormality of the calf musculature (HP:0001430)3.46486027
43Cystic hygroma (HP:0000476)3.44730529
44Calf muscle hypertrophy (HP:0008981)3.20453299
45EMG: myopathic abnormalities (HP:0003458)3.17703198
46Myotonia (HP:0002486)3.10770432
47Diminished movement (HP:0002374)3.00148326
48Abnormal auditory evoked potentials (HP:0006958)2.95436235
49Distal lower limb amyotrophy (HP:0008944)2.90091641
50Hyporeflexia of lower limbs (HP:0002600)2.89918130
51Abnormality of the left ventricular outflow tract (HP:0011103)2.86687590
52Subaortic stenosis (HP:0001682)2.86687590
53Abnormalities of placenta or umbilical cord (HP:0001194)2.85679208
54Muscle hypertrophy of the lower extremities (HP:0008968)2.85496757
55Generalized muscle weakness (HP:0003324)2.84623647
56Abnormality of skeletal muscle fiber size (HP:0012084)2.74699150
57Distal lower limb muscle weakness (HP:0009053)2.74147991
58Limited hip movement (HP:0008800)2.73669758
59Poor suck (HP:0002033)2.73306410
60Mask-like facies (HP:0000298)2.64733463
61Increased connective tissue (HP:0009025)2.63640621
62Webbed neck (HP:0000465)2.59327610
63Asymmetric septal hypertrophy (HP:0001670)2.59292640
64Metatarsus adductus (HP:0001840)2.56360335
65Long clavicles (HP:0000890)2.52026045
66Centrally nucleated skeletal muscle fibers (HP:0003687)2.47233880
67Areflexia of lower limbs (HP:0002522)2.45463949
68Muscle stiffness (HP:0003552)2.41666560
69Respiratory insufficiency due to muscle weakness (HP:0002747)2.35418842
70Limb-girdle muscle atrophy (HP:0003797)2.33191045
71Lower limb amyotrophy (HP:0007210)2.29972501
72Slender build (HP:0001533)2.28217666
73Knee flexion contracture (HP:0006380)2.27717302
74Arthrogryposis multiplex congenita (HP:0002804)2.19098001
75Neck muscle weakness (HP:0000467)2.17295098
76Increased variability in muscle fiber diameter (HP:0003557)2.16182927
77Hypoplastic ischia (HP:0003175)2.15786417
78Exercise-induced myalgia (HP:0003738)2.06786867
79Rimmed vacuoles (HP:0003805)2.00940390
80Nasal speech (HP:0001611)1.97614403
81Depressed nasal tip (HP:0000437)1.97277187
82Scapular winging (HP:0003691)1.97266410
83Bundle branch block (HP:0011710)1.94420762
84Distal upper limb amyotrophy (HP:0007149)1.92644005
85Upper limb amyotrophy (HP:0009129)1.92644005
86Vertebral fusion (HP:0002948)1.92300164
87Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.91709365
88Joint contractures involving the joints of the feet (HP:0100492)1.89410824
89Flexion contracture of toe (HP:0005830)1.89410824
90Abnormality of the ischium (HP:0003174)1.86382438
91Rhabdomyolysis (HP:0003201)1.84962803
92Ulnar deviation of finger (HP:0009465)1.79666148
93Increased density of long bones (HP:0006392)1.79486191
94Tarsal synostosis (HP:0008368)1.79213078
95Spinal rigidity (HP:0003306)1.79078234
96Frequent falls (HP:0002359)1.79013494
97Symphalangism affecting the phalanges of the hand (HP:0009773)1.77828354
98Neonatal respiratory distress (HP:0002643)1.76584046
99Myoglobinuria (HP:0002913)1.75679128
100Fused cervical vertebrae (HP:0002949)1.75656271
101Lipoatrophy (HP:0100578)1.74255832
102EMG: neuropathic changes (HP:0003445)1.71534750
103Abnormality of the shoulder girdle musculature (HP:0001435)1.70370710
104Bell-shaped thorax (HP:0001591)1.70168086
105Facial diplegia (HP:0001349)1.67793072
106Abnormal delivery (HP:0001787)1.67146658
107Decreased muscle mass (HP:0003199)1.67103553
108Short palpebral fissure (HP:0012745)1.63286147
109Shoulder girdle muscle weakness (HP:0003547)1.62543746
110Synostosis involving bones of the lower limbs (HP:0009138)1.62203938
111Synostosis involving bones of the feet (HP:0009140)1.62203938
112Rocker bottom foot (HP:0001838)1.61594273
113Waddling gait (HP:0002515)1.61365026
114Sudden death (HP:0001699)1.59923071
115Pelvic girdle muscle weakness (HP:0003749)1.59613700
116Ulnar deviation of the hand or of fingers of the hand (HP:0001193)1.58051858
117Nonprogressive disorder (HP:0003680)1.57579511
118Generalized amyotrophy (HP:0003700)1.56887007
119Abnormality of the musculature of the pelvis (HP:0001469)1.54245161
120Abnormality of the hip-girdle musculature (HP:0001445)1.54245161
121Infantile muscular hypotonia (HP:0008947)1.49986462
122Adducted thumb (HP:0001181)1.49976293
123Dilated cardiomyopathy (HP:0001644)1.44696906

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MOS8.79101109
2MUSK8.20315793
3PIK3CG4.68051796
4TRIB34.55617558
5PIM23.59814428
6MAP2K12.67926862
7OBSCN2.05181681
8CDK152.02201941
9CDK142.01738734
10MAP3K102.00391625
11CDK181.94207740
12CDK61.92204229
13CCNB11.89653952
14CDK11A1.87668419
15PINK11.69188206
16PKN21.63621731
17EPHB11.62823417
18PAK41.55583255
19DYRK1B1.35583229
20AKT21.27528058
21ILK1.26964682
22GRK11.14497733
23MAPK121.09161480
24DDR21.09109931
25PTK61.08411107
26MAP3K51.02855343
27TTN1.02405854
28BCKDK1.00264125
29PRKD20.86112078
30RIPK10.85986931
31DAPK30.84069041
32NEK90.83833865
33EPHB20.82427788
34PTK20.78800067
35ICK0.75945541
36ROCK20.74965742
37MTOR0.74708819
38MARK10.68211249
39PBK0.67466285
40LIMK10.65858273
41TIE10.65403228
42FGFR40.64389550
43MAPK70.62769869
44SIK10.62739558
45STK160.61371802
46MAP3K70.61278927
47MAPKAPK50.61183324
48LATS20.56804633
49MAP2K30.55907295
50PDGFRA0.55330879
51ABL10.54761271
52CDK50.54470703
53MARK20.52701284
54KSR10.52059380
55DAPK20.51511076
56LRRK20.51209363
57CDK80.49821487
58DMPK0.47207726
59ALK0.45512698
60ADRBK20.44611156
61ROCK10.43857414
62MAPK100.43823801
63PRKACB0.43651195
64PRKD30.43470332
65TYRO30.42690941
66CAMK2B0.38520231
67EEF2K0.38179763
68CDK90.36537993
69PRKACA0.35985682
70PDPK10.35726846
71MYLK0.35472404
72PDK20.33968154
73ARAF0.33333288
74FGFR10.32921999
75RPS6KA30.31804110
76MAPKAPK30.31486079
77PTK2B0.31477000
78ERN10.31051654
79PLK20.30527884
80NTRK20.30352062
81RPS6KB10.29933630
82STK110.29597885
83PKN10.29515100
84PAK20.29407739
85PHKG10.28579095
86PHKG20.28579095
87PIK3CA0.28404232
88NEK10.28195603
89PRKAA10.27784516
90MAP2K40.27229240
91VRK20.27160502
92PAK30.26503103
93FER0.26284326
94BMX0.26193578
95TNIK0.26132300
96LATS10.24628282
97PRKG10.23543985
98PRKG20.23130632
99* CAMK2A0.23019680
100PRKCG0.23008275
101FLT30.22541664
102TGFBR20.21893750
103INSRR0.20951467
104MAPK130.20695064
105PDK10.20206981
106MAPK40.18981975
107CAMK10.18522608
108INSR0.18342806
109CAMKK10.18166072
110NME10.18104842
111KSR20.17784329
112PAK60.17707879
113HIPK20.17581802
114MAPK90.16760183
115CAMK2G0.16582501
116CSNK1G20.16276018
117BMPR1B0.15102685
118* PRKCA0.15077083
119MAP2K60.14902559
120PDK40.14646406
121PDK30.14646406
122CDK190.14095399
123PDGFRB0.13821020
124PIM10.13560477
125CAMK40.12461648
126BRAF0.11877824
127MAP3K130.11541580
128MAP3K90.11463560
129SRC0.11334383
130ERBB30.10905175
131PAK10.10713365
132AURKA0.10628808
133RET0.10609446
134CSK0.10046607
135AKT10.09939016
136PRKD10.09844455
137CAMK2D0.09695801
138ABL20.09582402
139PRKAA20.09417151
140CSNK1D0.09234581
141MAPK110.09152728
142MELK0.07715056
143TRPM70.07684033
144ERBB20.07345487
145MAPK80.06744979
146PRKCH0.06669483

Predicted pathways (KEGG)

RankGene SetZ-score
1Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054104.93627728
2Dilated cardiomyopathy_Homo sapiens_hsa054144.85278652
3Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054124.45383740
4Cardiac muscle contraction_Homo sapiens_hsa042603.06204626
5Tight junction_Homo sapiens_hsa045302.89522884
6Focal adhesion_Homo sapiens_hsa045102.28634195
7Proteoglycans in cancer_Homo sapiens_hsa052052.28300425
8Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042612.23982206
9Viral myocarditis_Homo sapiens_hsa054162.00660793
10Bladder cancer_Homo sapiens_hsa052191.95148113
11Chronic myeloid leukemia_Homo sapiens_hsa052201.86116201
12Oxytocin signaling pathway_Homo sapiens_hsa049211.81932370
13Alzheimers disease_Homo sapiens_hsa050101.79856309
14Parkinsons disease_Homo sapiens_hsa050121.78598344
15Circadian rhythm_Homo sapiens_hsa047101.70666370
16Oxidative phosphorylation_Homo sapiens_hsa001901.60280491
17ECM-receptor interaction_Homo sapiens_hsa045121.50639340
18Glioma_Homo sapiens_hsa052141.47023023
19Arginine and proline metabolism_Homo sapiens_hsa003301.36219268
20Protein digestion and absorption_Homo sapiens_hsa049741.35648998
21Insulin signaling pathway_Homo sapiens_hsa049101.35332087
22Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.31438240
23Adherens junction_Homo sapiens_hsa045201.30692141
24Hippo signaling pathway_Homo sapiens_hsa043901.25700696
25Prion diseases_Homo sapiens_hsa050201.21476945
26Amoebiasis_Homo sapiens_hsa051461.21054708
27Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.20397360
28MAPK signaling pathway_Homo sapiens_hsa040101.19009137
29Melanoma_Homo sapiens_hsa052181.18797301
30Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.17232743
31Glucagon signaling pathway_Homo sapiens_hsa049221.15226606
32Phototransduction_Homo sapiens_hsa047441.13926952
33Sulfur metabolism_Homo sapiens_hsa009201.10919838
34Leukocyte transendothelial migration_Homo sapiens_hsa046701.09139389
35Basal cell carcinoma_Homo sapiens_hsa052171.09103049
36Hedgehog signaling pathway_Homo sapiens_hsa043401.08392244
37Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.07718017
38Renal cell carcinoma_Homo sapiens_hsa052111.06696425
39Regulation of actin cytoskeleton_Homo sapiens_hsa048101.05810664
40Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.04128568
41Pyruvate metabolism_Homo sapiens_hsa006201.04037750
42Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.04029002
43Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.02319688
44Ribosome_Homo sapiens_hsa030101.01739838
45Melanogenesis_Homo sapiens_hsa049161.01602471
46Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.96273528
47Vascular smooth muscle contraction_Homo sapiens_hsa042700.95110864
48ErbB signaling pathway_Homo sapiens_hsa040120.94504770
49FoxO signaling pathway_Homo sapiens_hsa040680.93633474
50Axon guidance_Homo sapiens_hsa043600.93597832
51Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.93522200
52Salmonella infection_Homo sapiens_hsa051320.93036081
53Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.89585037
54mTOR signaling pathway_Homo sapiens_hsa041500.89581687
55Central carbon metabolism in cancer_Homo sapiens_hsa052300.89326469
56Huntingtons disease_Homo sapiens_hsa050160.89216188
57Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.86370270
58HIF-1 signaling pathway_Homo sapiens_hsa040660.85884982
59Prostate cancer_Homo sapiens_hsa052150.85472175
60Gap junction_Homo sapiens_hsa045400.84000477
61Pancreatic cancer_Homo sapiens_hsa052120.83474253
62Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.80954851
63Adipocytokine signaling pathway_Homo sapiens_hsa049200.79786153
64Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.78957765
65VEGF signaling pathway_Homo sapiens_hsa043700.77480397
66cGMP-PKG signaling pathway_Homo sapiens_hsa040220.77104954
67Insulin resistance_Homo sapiens_hsa049310.76055852
68Non-small cell lung cancer_Homo sapiens_hsa052230.73875763
69Cholinergic synapse_Homo sapiens_hsa047250.73836472
70Platelet activation_Homo sapiens_hsa046110.72431280
71TGF-beta signaling pathway_Homo sapiens_hsa043500.72370904
72Longevity regulating pathway - mammal_Homo sapiens_hsa042110.71210714
73Wnt signaling pathway_Homo sapiens_hsa043100.70620000
74GnRH signaling pathway_Homo sapiens_hsa049120.68453683
75B cell receptor signaling pathway_Homo sapiens_hsa046620.65983550
76AMPK signaling pathway_Homo sapiens_hsa041520.65902464
77Renin-angiotensin system_Homo sapiens_hsa046140.65741741
78MicroRNAs in cancer_Homo sapiens_hsa052060.65407489
79Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.64391874
802-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.63465915
81Nitrogen metabolism_Homo sapiens_hsa009100.62735793
82Dorso-ventral axis formation_Homo sapiens_hsa043200.61164796
83Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.60777140
84Insulin secretion_Homo sapiens_hsa049110.60439452
85Renin secretion_Homo sapiens_hsa049240.59702644
86Estrogen signaling pathway_Homo sapiens_hsa049150.58963383
87Acute myeloid leukemia_Homo sapiens_hsa052210.57965466
88cAMP signaling pathway_Homo sapiens_hsa040240.55686562
89Endocytosis_Homo sapiens_hsa041440.55546374
90Endometrial cancer_Homo sapiens_hsa052130.55220221
91Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.54045466
92Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.53933452
93Tryptophan metabolism_Homo sapiens_hsa003800.53926949
94Neurotrophin signaling pathway_Homo sapiens_hsa047220.53431487
95HTLV-I infection_Homo sapiens_hsa051660.53375396
96Olfactory transduction_Homo sapiens_hsa047400.52919349
97Starch and sucrose metabolism_Homo sapiens_hsa005000.51322663
98Long-term depression_Homo sapiens_hsa047300.50502106
99AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.49343929
100Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.49248296
101Calcium signaling pathway_Homo sapiens_hsa040200.47840753
102Biosynthesis of amino acids_Homo sapiens_hsa012300.46019769
103Carbon metabolism_Homo sapiens_hsa012000.45893994
104Pathways in cancer_Homo sapiens_hsa052000.45802567
105Cocaine addiction_Homo sapiens_hsa050300.45080629
106Aldosterone synthesis and secretion_Homo sapiens_hsa049250.44586002
107Fatty acid degradation_Homo sapiens_hsa000710.44455191
108Bile secretion_Homo sapiens_hsa049760.44367798
109Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.44016303
110Sulfur relay system_Homo sapiens_hsa041220.43766341
111PI3K-Akt signaling pathway_Homo sapiens_hsa041510.43737441
112Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.43709581
113Small cell lung cancer_Homo sapiens_hsa052220.43455463
114Arginine biosynthesis_Homo sapiens_hsa002200.42505639
115Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.40893152
116Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.40654595
117Gastric acid secretion_Homo sapiens_hsa049710.40409344
118Selenocompound metabolism_Homo sapiens_hsa004500.40351874
119Circadian entrainment_Homo sapiens_hsa047130.40315553
120Colorectal cancer_Homo sapiens_hsa052100.40113073
121Hepatitis B_Homo sapiens_hsa051610.39856377
122Notch signaling pathway_Homo sapiens_hsa043300.39316736
123Propanoate metabolism_Homo sapiens_hsa006400.38511360
124Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.38269816
125Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.37582531
126Rap1 signaling pathway_Homo sapiens_hsa040150.36832255
127Long-term potentiation_Homo sapiens_hsa047200.36401757
128RNA degradation_Homo sapiens_hsa030180.35899344
129beta-Alanine metabolism_Homo sapiens_hsa004100.35867361
130Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.35101143
131Carbohydrate digestion and absorption_Homo sapiens_hsa049730.34261985
132Salivary secretion_Homo sapiens_hsa049700.34133780
133Ras signaling pathway_Homo sapiens_hsa040140.33309390
134Folate biosynthesis_Homo sapiens_hsa007900.30887436
135RNA polymerase_Homo sapiens_hsa030200.27838122
136Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.26500167
137Cyanoamino acid metabolism_Homo sapiens_hsa004600.23073816
138Thyroid hormone synthesis_Homo sapiens_hsa049180.21363042
139Histidine metabolism_Homo sapiens_hsa003400.20440781
140Amphetamine addiction_Homo sapiens_hsa050310.19900983

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »