MYOZ3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is specifically expressed in the skeletal muscle, and belongs to the myozenin family. Members of this family function as calcineurin-interacting proteins that help tether calcineurin to the sarcomere of cardiac and skeletal muscle. They play an important role in modulation of calcineurin signaling. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1actin-mediated cell contraction (GO:0070252)9.94888512
2skeletal muscle fiber development (GO:0048741)8.35232688
3actin filament-based movement (GO:0030048)7.43781129
4glycogen catabolic process (GO:0005980)7.24008587
5positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)7.20706585
6myotube cell development (GO:0014904)7.11454291
7purine nucleotide salvage (GO:0032261)7.01731868
8response to stimulus involved in regulation of muscle adaptation (GO:0014874)6.85498223
9glucan catabolic process (GO:0009251)6.77901086
10striated muscle atrophy (GO:0014891)6.68682788
11creatine metabolic process (GO:0006600)6.58151775
12plasma membrane repair (GO:0001778)6.47085342
13sarcomere organization (GO:0045214)6.45781085
14skeletal muscle tissue regeneration (GO:0043403)6.44576917
15striated muscle contraction (GO:0006941)6.42609229
16carnitine shuttle (GO:0006853)6.36534843
17cellular polysaccharide catabolic process (GO:0044247)6.33624094
18polysaccharide catabolic process (GO:0000272)6.05606861
19response to muscle activity (GO:0014850)6.03782135
20IMP metabolic process (GO:0046040)5.82583703
21regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)5.81067993
22muscle atrophy (GO:0014889)5.78752712
23myofibril assembly (GO:0030239)5.75788720
24striated muscle adaptation (GO:0014888)5.61061700
25pyrimidine ribonucleoside catabolic process (GO:0046133)5.58361354
26regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)5.55034467
27regulation of cell communication by electrical coupling (GO:0010649)5.54037392
28response to inactivity (GO:0014854)5.50526086
29muscle contraction (GO:0006936)5.49650891
30fatty acid transmembrane transport (GO:1902001)5.30820551
31glucan biosynthetic process (GO:0009250)5.27502683
32glycogen biosynthetic process (GO:0005978)5.27502683
33cardiac myofibril assembly (GO:0055003)5.23252257
34cytidine deamination (GO:0009972)5.12210132
35cytidine metabolic process (GO:0046087)5.12210132
36cytidine catabolic process (GO:0006216)5.12210132
37regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)5.10094703
38muscle fiber development (GO:0048747)5.06003535
39muscle system process (GO:0003012)4.88595315
40positive regulation of mitochondrial calcium ion concentration (GO:0051561)4.84569218
41glycogen metabolic process (GO:0005977)4.71199181
42carnitine transmembrane transport (GO:1902603)4.67031685
43regulation of acyl-CoA biosynthetic process (GO:0050812)4.64357833
44neuronal action potential propagation (GO:0019227)4.63194854
45cellular glucan metabolic process (GO:0006073)4.61716715
46glucan metabolic process (GO:0044042)4.61716715
47regulation of actin filament-based movement (GO:1903115)4.52706820
48muscle adaptation (GO:0043500)4.52229048
49actomyosin structure organization (GO:0031032)4.50174359
50cardiac muscle hypertrophy (GO:0003300)4.35997446
51negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.34617322
52IMP biosynthetic process (GO:0006188)4.32501093
53muscle organ morphogenesis (GO:0048644)4.32123571
54NADH metabolic process (GO:0006734)4.30925029
55negative regulation of skeletal muscle tissue development (GO:0048642)4.29802953
56amino-acid betaine transport (GO:0015838)4.28551361
57carnitine transport (GO:0015879)4.28551361
58response to activity (GO:0014823)4.17956443
592-oxoglutarate metabolic process (GO:0006103)4.17709465
60regulation of cofactor metabolic process (GO:0051193)4.17291324
61regulation of coenzyme metabolic process (GO:0051196)4.17291324
62striated muscle hypertrophy (GO:0014897)4.16642239
63ubiquinone biosynthetic process (GO:0006744)4.14153902
64cellular carbohydrate catabolic process (GO:0044275)4.11011028
65cellular response to dexamethasone stimulus (GO:0071549)4.10801321
66regulation of skeletal muscle cell differentiation (GO:2001014)3.98314380
67fructose metabolic process (GO:0006000)3.90783952
68negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.90357059
69negative regulation of muscle hypertrophy (GO:0014741)3.87297344
70muscle organ development (GO:0007517)3.87018222
71neuromuscular synaptic transmission (GO:0007274)3.85050015
72regulation of relaxation of muscle (GO:1901077)3.83157971
73response to dexamethasone (GO:0071548)3.83024554
74muscle structure development (GO:0061061)3.82874407
75muscle cell fate commitment (GO:0042693)3.80529634
76adult heart development (GO:0007512)3.77614690
77ubiquinone metabolic process (GO:0006743)3.77056380
78myotube differentiation (GO:0014902)3.76886881
79striated muscle cell development (GO:0055002)3.74587406
80muscle hypertrophy (GO:0014896)3.70133201
81negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.69189271
82negative regulation of calcium ion transmembrane transport (GO:1903170)3.69189271
83regulation of striated muscle contraction (GO:0006942)3.67668815
84muscle tissue morphogenesis (GO:0060415)3.66544742
85muscle cell cellular homeostasis (GO:0046716)3.66030341
86regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.60748074
87regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.60688724
88gluconeogenesis (GO:0006094)3.59986293
89otic vesicle formation (GO:0030916)3.58423916
90cardiac muscle contraction (GO:0060048)3.55883353
91negative regulation of cAMP-mediated signaling (GO:0043951)3.49054385
92regulation of sulfur metabolic process (GO:0042762)3.47213897
93cardiac muscle tissue morphogenesis (GO:0055008)3.45480519
94heart contraction (GO:0060047)3.43901199
95heart process (GO:0003015)3.43901199
96tricarboxylic acid cycle (GO:0006099)3.42753517
97negative regulation of potassium ion transmembrane transport (GO:1901380)3.41556374
98intracellular lipid transport (GO:0032365)3.36971229
99negative regulation of muscle contraction (GO:0045932)3.35786346
100skeletal muscle tissue development (GO:0007519)3.35216881
101cardiac muscle cell development (GO:0055013)3.34913186
102cellular polysaccharide metabolic process (GO:0044264)3.33607878
103quinone biosynthetic process (GO:1901663)3.33403789
104regulation of calcium ion transmembrane transport (GO:1903169)3.30733632
105regulation of calcium ion transmembrane transporter activity (GO:1901019)3.30733632
106regulation of sequestering of triglyceride (GO:0010889)3.29883163
107aspartate family amino acid catabolic process (GO:0009068)3.27384067
108myoblast fusion (GO:0007520)3.26170387
109relaxation of muscle (GO:0090075)3.25715193
110positive regulation of myotube differentiation (GO:0010831)3.23748724
111AMP metabolic process (GO:0046033)3.20854233
112negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.20375616
113nucleotide salvage (GO:0043173)3.19546047
114hexose biosynthetic process (GO:0019319)3.19316173
115cardiac muscle hypertrophy in response to stress (GO:0014898)3.18094516
116muscle hypertrophy in response to stress (GO:0003299)3.18094516
117cardiac muscle adaptation (GO:0014887)3.18094516
118cellular polysaccharide biosynthetic process (GO:0033692)3.17664670
119muscle cell development (GO:0055001)3.16833554
120neuromuscular junction development (GO:0007528)3.16527874
121purine-containing compound salvage (GO:0043101)3.13522838
122polysaccharide biosynthetic process (GO:0000271)3.12293047
123positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.11146248
124positive regulation of cation channel activity (GO:2001259)3.09469465
125endoplasmic reticulum organization (GO:0007029)3.09134113
126polysaccharide metabolic process (GO:0005976)3.07920083
127positive regulation of myoblast differentiation (GO:0045663)3.07206370
128regulation of skeletal muscle contraction (GO:0014819)12.5428403
129muscle filament sliding (GO:0030049)12.0869162
130actin-myosin filament sliding (GO:0033275)12.0869162
131skeletal muscle adaptation (GO:0043501)11.1108181
132skeletal muscle contraction (GO:0003009)10.9627308
133sarcoplasmic reticulum calcium ion transport (GO:0070296)10.6561834

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human9.76616100
2ESR1_20079471_ChIP-ChIP_T-47D_Human3.83823159
3PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.73207828
4RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.40653251
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.32062677
6GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.19988289
7TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse3.18116917
8ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.83586685
9BCL3_23251550_ChIP-Seq_MUSCLE_Mouse2.75730607
10PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.75432248
11IGF1R_20145208_ChIP-Seq_DFB_Human2.56835006
12CDX2_19796622_ChIP-Seq_MESCs_Mouse2.43709230
13TBX20_22080862_ChIP-Seq_HEART_Mouse2.41782907
14TBX20_22328084_ChIP-Seq_HEART_Mouse2.41782907
15ZNF263_19887448_ChIP-Seq_K562_Human2.34570335
16AR_21572438_ChIP-Seq_LNCaP_Human2.28865280
17ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.14927618
18FLI1_27457419_Chip-Seq_LIVER_Mouse1.94116856
19EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.90947315
20CTCF_21964334_ChIP-Seq_BJAB-B_Human1.89054257
21MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.82941871
22ESR1_21235772_ChIP-Seq_MCF-7_Human1.82369238
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.79153455
24PCGF2_27294783_Chip-Seq_ESCs_Mouse1.68963046
25GBX2_23144817_ChIP-Seq_PC3_Human1.65660337
26RARG_19884340_ChIP-ChIP_MEFs_Mouse1.62582724
27* CTCF_27219007_Chip-Seq_Bcells_Human1.60859982
28STAT1_20625510_ChIP-Seq_HELA_Human1.52271169
29LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.51111094
30HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.48476281
31CRX_20693478_ChIP-Seq_RETINA_Mouse1.44607774
32* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.44139049
33EZH2_22144423_ChIP-Seq_EOC_Human1.44005874
34PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.43994859
35ZNF274_21170338_ChIP-Seq_K562_Hela1.43179873
36EZH2_27294783_Chip-Seq_NPCs_Mouse1.42384540
37SUZ12_27294783_Chip-Seq_NPCs_Mouse1.42009796
38RBPJ_22232070_ChIP-Seq_NCS_Mouse1.41320215
39CBX2_27304074_Chip-Seq_ESCs_Mouse1.39706002
40THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.39159811
41* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.38890991
42ESR2_21235772_ChIP-Seq_MCF-7_Human1.38512603
43OCT4_20526341_ChIP-Seq_ESCs_Human1.37755991
44FOXH1_21741376_ChIP-Seq_ESCs_Human1.37327514
45STAT6_21828071_ChIP-Seq_BEAS2B_Human1.33649622
46SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.32492733
47SRF_21415370_ChIP-Seq_HL-1_Mouse1.32282854
48ER_23166858_ChIP-Seq_MCF-7_Human1.29881602
49SA1_27219007_Chip-Seq_Bcells_Human1.28959138
50EP300_21415370_ChIP-Seq_HL-1_Mouse1.28683216
51FUS_26573619_Chip-Seq_HEK293_Human1.27630422
52HTT_18923047_ChIP-ChIP_STHdh_Human1.24604948
53TDRD3_21172665_ChIP-Seq_MCF-7_Human1.24551958
54CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.24022507
55NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.23998310
56TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.23997845
57CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.23226861
58NANOG_20526341_ChIP-Seq_ESCs_Human1.22926368
59* NANOG_19829295_ChIP-Seq_ESCs_Human1.22730554
60* SOX2_19829295_ChIP-Seq_ESCs_Human1.22730554
61DNAJC2_21179169_ChIP-ChIP_NT2_Human1.21760777
62CTCF_21964334_Chip-Seq_Bcells_Human1.21688426
63OCT4_21477851_ChIP-Seq_ESCs_Mouse1.20702697
64SMC1_22415368_ChIP-Seq_MEFs_Mouse1.19680684
65NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.18022992
66SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.17762040
67HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.17186738
68* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.16770186
69* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.15902527
70E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.15270856
71* KDM2B_26808549_Chip-Seq_DND41_Human1.15197329
72GATA4_21415370_ChIP-Seq_HL-1_Mouse1.14021149
73PPARA_22158963_ChIP-Seq_LIVER_Mouse1.13971990
74* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.13765975
75GATA6_21074721_ChIP-Seq_CACO-2_Human1.12398121
76ESR1_15608294_ChIP-ChIP_MCF-7_Human1.12027460
77ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.11450520
78GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.10407725
79SMC3_22415368_ChIP-Seq_MEFs_Mouse1.10058517
80MYC_27129775_Chip-Seq_CORNEA_Mouse1.09716711
81P53_21459846_ChIP-Seq_SAOS-2_Human1.08094896
82YY1_22570637_ChIP-Seq_MALME-3M_Human1.07531636
83ZFP57_27257070_Chip-Seq_ESCs_Mouse1.07290284
84P53_22127205_ChIP-Seq_FIBROBLAST_Human1.05602426
85RAC3_21632823_ChIP-Seq_H3396_Human1.04993513
86PHF8_20622853_ChIP-Seq_HELA_Human1.04611229
87UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.04545772
88CTCF_27219007_Chip-Seq_ERYTHROID_Human1.04307621
89ATF3_27146783_Chip-Seq_COLON_Human1.02946058
90OCT1_27270436_Chip-Seq_PROSTATE_Human1.02936434
91CTCF_26484167_Chip-Seq_Bcells_Mouse1.02921252
92* CREB1_26743006_Chip-Seq_LNCaP_Human1.02296744
93GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.02005514
94CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.01829029
95TP53_22573176_ChIP-Seq_HFKS_Human1.01812965
96VDR_22108803_ChIP-Seq_LS180_Human1.01614213
97CEBPB_22108803_ChIP-Seq_LS180_Human1.00870190
98* CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.99327247
99POU3F2_20337985_ChIP-ChIP_501MEL_Human0.97885664
100P68_20966046_ChIP-Seq_HELA_Human0.96693861
101SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.96651989
102NFE2_27457419_Chip-Seq_LIVER_Mouse0.96352548
103TOP2B_26459242_ChIP-Seq_MCF-7_Human0.96187769
104* TCF7_22412390_ChIP-Seq_EML_Mouse0.94455249
105PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.94190840
106ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93927524
107RXR_22158963_ChIP-Seq_LIVER_Mouse0.93484382
108GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse0.93137761
109KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.92491238
110RACK7_27058665_Chip-Seq_MCF-7_Human0.92440025
111CJUN_26792858_Chip-Seq_BT549_Human0.92340553
112AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.92317422
113NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.91857293
114TP63_22573176_ChIP-Seq_HFKS_Human0.91067571
115FLI1_21867929_ChIP-Seq_TH2_Mouse0.90472647
116ETV1_20927104_ChIP-Seq_GIST48_Human0.90199945
117LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.89844318
118FOXH1_21741376_ChIP-Seq_EPCs_Human0.88950990
119NFYB_21822215_ChIP-Seq_K562_Human0.88564570
120NFIB_24661679_ChIP-Seq_LUNG_Mouse0.88289479
121P300_27058665_Chip-Seq_ZR-75-30cells_Human0.88224632
122DROSHA_22980978_ChIP-Seq_HELA_Human0.87659276
123ELF1_20517297_ChIP-Seq_JURKAT_Human0.87035138
124SOX2_21211035_ChIP-Seq_LN229_Gbm0.86726744
125TP53_20018659_ChIP-ChIP_R1E_Mouse0.85745367
126EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.85457340
127MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.85378210
128PCGF2_27294783_Chip-Seq_NPCs_Mouse0.85255471
129SPI1_20517297_ChIP-Seq_HL60_Human0.85016998
130RBPJ_21746931_ChIP-Seq_IB4_Human0.84863691
131FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.84819595
132RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.84739419
133SMAD_19615063_ChIP-ChIP_OVARY_Human0.84526132
134SMAD4_21741376_ChIP-Seq_EPCs_Human0.84029900
135PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.83900115
136CBP_21632823_ChIP-Seq_H3396_Human0.83512658
137* IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.83508895
138* CBP_20019798_ChIP-Seq_JUKART_Human0.83508895
139FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.83420461
140HOXB7_26014856_ChIP-Seq_BT474_Human0.83286232
141CLOCK_20551151_ChIP-Seq_293T_Human0.83239811
142CSB_26484114_Chip-Seq_FIBROBLAST_Human0.83232662
143SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.82576822
144MYC_19829295_ChIP-Seq_ESCs_Human0.82565074
145EZH2_27294783_Chip-Seq_ESCs_Mouse0.82444338
146E2F1_20622854_ChIP-Seq_HELA_Human0.82245231
147CBX2_22325352_ChIP-Seq_293T-Rex_Human0.80827116
148HNFA_21074721_ChIP-Seq_CACO-2_Human0.80664494
149LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.79601836
150UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.78370623
151EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.77563733
152THAP11_20581084_ChIP-Seq_MESCs_Mouse0.76725789
153* AUTS2_25519132_ChIP-Seq_293T-REX_Human0.75596217
154NCOR_22424771_ChIP-Seq_293T_Human0.75246824

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004145_abnormal_muscle_electrophysio8.27273294
2MP0003646_muscle_fatigue7.35921095
3MP0000749_muscle_degeneration6.34828948
4MP0000751_myopathy5.55737449
5MP0000747_muscle_weakness4.35989861
6MP0002106_abnormal_muscle_physiology4.31384045
7MP0004036_abnormal_muscle_relaxation4.08831288
8MP0000759_abnormal_skeletal_muscle3.84255409
9MP0002269_muscular_atrophy3.69536622
10MP0005369_muscle_phenotype3.54373257
11MP0004087_abnormal_muscle_fiber3.33600103
12MP0004130_abnormal_muscle_cell3.30859544
13MP0002837_dystrophic_cardiac_calcinosis3.27673862
14MP0000750_abnormal_muscle_regeneration3.20858564
15MP0005620_abnormal_muscle_contractility3.12646251
16MP0004233_abnormal_muscle_weight2.70880721
17MP0000733_abnormal_muscle_development2.39393163
18MP0002332_abnormal_exercise_endurance2.31358291
19MP0004185_abnormal_adipocyte_glucose1.95236374
20MP0006036_abnormal_mitochondrial_physio1.90967346
21MP0002108_abnormal_muscle_morphology1.86076073
22MP0005330_cardiomyopathy1.63609502
23MP0005666_abnormal_adipose_tissue1.41376469
24MP0004270_analgesia1.40923331
25MP0002971_abnormal_brown_adipose1.38124398
26MP0004084_abnormal_cardiac_muscle1.34481162
27MP0003806_abnormal_nucleotide_metabolis1.30627950
28MP0003221_abnormal_cardiomyocyte_apopto1.19495156
29MP0002972_abnormal_cardiac_muscle1.12528615
30MP0005266_abnormal_metabolism1.11299984
31MP0004484_altered_response_of1.10787322
32MP0001661_extended_life_span1.10252698
33MP0004215_abnormal_myocardial_fiber1.06764321
34MP0010630_abnormal_cardiac_muscle1.05448506
35MP0002822_catalepsy1.04836667
36MP0005375_adipose_tissue_phenotype1.02098319
37MP0003705_abnormal_hypodermis_morpholog0.92565303
38MP0006035_abnormal_mitochondrial_morpho0.91900110
39MP0003950_abnormal_plasma_membrane0.87644543
40MP0003656_abnormal_erythrocyte_physiolo0.85433422
41MP0002234_abnormal_pharynx_morphology0.81174518
42MP0004134_abnormal_chest_morphology0.79168264
43MP0000372_irregular_coat_pigmentation0.79146558
44MP0009250_abnormal_appendicular_skeleto0.79107463
45MP0005385_cardiovascular_system_phenoty0.76570025
46MP0001544_abnormal_cardiovascular_syste0.76570025
47MP0004085_abnormal_heartbeat0.76087109
48MP0000013_abnormal_adipose_tissue0.75995609
49MP0002638_abnormal_pupillary_reflex0.74326276
50MP0005451_abnormal_body_composition0.72388635
51MP0008961_abnormal_basal_metabolism0.71302588
52MP0000762_abnormal_tongue_morphology0.69965293
53MP0004043_abnormal_pH_regulation0.69148361
54MP0005645_abnormal_hypothalamus_physiol0.68354816
55MP0001299_abnormal_eye_distance/0.67098228
56MP0004147_increased_porphyrin_level0.64626486
57MP0005334_abnormal_fat_pad0.64542300
58MP0002078_abnormal_glucose_homeostasis0.61814818
59MP0009780_abnormal_chondrocyte_physiolo0.59846342
60MP0003137_abnormal_impulse_conducting0.59544872
61MP0006276_abnormal_autonomic_nervous0.58657761
62MP0002734_abnormal_mechanical_nocicepti0.54747481
63MP0000003_abnormal_adipose_tissue0.54575951
64MP0005167_abnormal_blood-brain_barrier0.54150793
65MP0002127_abnormal_cardiovascular_syste0.53725897
66MP0005670_abnormal_white_adipose0.52390634
67MP0000266_abnormal_heart_morphology0.49595545
68MP0005275_abnormal_skin_tensile0.49526887
69MP0010030_abnormal_orbit_morphology0.48392972
70MP0003136_yellow_coat_color0.47931557
71MP0003011_delayed_dark_adaptation0.47680783
72MP0001849_ear_inflammation0.47582628
73MP0000579_abnormal_nail_morphology0.47339310
74MP0005332_abnormal_amino_acid0.46775566
75MP0001529_abnormal_vocalization0.44626561
76MP0005452_abnormal_adipose_tissue0.44612556
77MP0000343_altered_response_to0.44518930
78MP0005423_abnormal_somatic_nervous0.44353348
79MP0008775_abnormal_heart_ventricle0.42358049
80MP0008872_abnormal_physiological_respon0.41910680
81MP0009672_abnormal_birth_weight0.41555096
82MP0005584_abnormal_enzyme/coenzyme_acti0.40671497
83MP0005083_abnormal_biliary_tract0.39775686
84MP0002089_abnormal_postnatal_growth/wei0.39090178
85MP0008569_lethality_at_weaning0.38708232
86MP0003879_abnormal_hair_cell0.38591938
87MP0003959_abnormal_lean_body0.37445880
88MP0001346_abnormal_lacrimal_gland0.37286084
89MP0002876_abnormal_thyroid_physiology0.35400299
90MP0003045_fibrosis0.35294302
91MP0002114_abnormal_axial_skeleton0.35113798
92MP0004142_abnormal_muscle_tone0.33970751
93MP0002896_abnormal_bone_mineralization0.33602165
94MP0009115_abnormal_fat_cell0.33442545
95MP0002067_abnormal_sensory_capabilities0.32140365
96MP0000678_abnormal_parathyroid_gland0.32035321
97MP0002796_impaired_skin_barrier0.30023901
98MP0001986_abnormal_taste_sensitivity0.28811237
99MP0000383_abnormal_hair_follicle0.28399174
100MP0002128_abnormal_blood_circulation0.28247406
101MP0005319_abnormal_enzyme/_coenzyme0.28054297
102MP0001243_abnormal_dermal_layer0.27918018
103MP0003941_abnormal_skin_development0.27625506
104MP0003828_pulmonary_edema0.27518052
105MP0009697_abnormal_copulation0.26938129
106MP0006138_congestive_heart_failure0.26441114
107MP0002066_abnormal_motor_capabilities/c0.26220615
108MP0003948_abnormal_gas_homeostasis0.26156265
109MP0003755_abnormal_palate_morphology0.25417740
110MP0004510_myositis0.25193548
111MP0006292_abnormal_olfactory_placode0.25062928
112MP0005376_homeostasis/metabolism_phenot0.24997787
113MP0004924_abnormal_behavior0.23898337
114MP0000230_abnormal_systemic_arterial0.21958262
115MP0003195_calcinosis0.21830987
116MP0002118_abnormal_lipid_homeostasis0.21611811
117MP0003567_abnormal_fetal_cardiomyocyte0.21121152
118MP0005535_abnormal_body_temperature0.21072135
119MP0005187_abnormal_penis_morphology0.20903975
120MP0005076_abnormal_cell_differentiation0.20596299
121MP0002139_abnormal_hepatobiliary_system0.19650480
122MP0008770_decreased_survivor_rate0.19378162
123MP0003385_abnormal_body_wall0.19075225
124MP0002932_abnormal_joint_morphology0.17769282
125MP0002109_abnormal_limb_morphology0.16556536
126MP0000427_abnormal_hair_cycle0.16419357
127MP0001943_abnormal_respiration0.16244637
128MP0002970_abnormal_white_adipose0.16054892

Predicted human phenotypes

RankGene SetZ-score
1Muscle fiber inclusion bodies (HP:0100299)9.70392474
2Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)9.34089062
3Exercise-induced myalgia (HP:0003738)9.26547248
4Nemaline bodies (HP:0003798)8.59791417
5Exercise-induced muscle cramps (HP:0003710)8.42822827
6Muscle hypertrophy of the lower extremities (HP:0008968)7.20851084
7Distal arthrogryposis (HP:0005684)7.07527499
8Myopathic facies (HP:0002058)6.85021637
9Type 1 muscle fiber predominance (HP:0003803)6.82966526
10Calf muscle hypertrophy (HP:0008981)6.25245613
11Round ear (HP:0100830)6.13219313
12Ulnar deviation of the wrist (HP:0003049)6.06400137
13Difficulty running (HP:0009046)5.75625085
14Myoglobinuria (HP:0002913)5.52951903
15Calcaneovalgus deformity (HP:0001848)5.33719634
16Muscle fiber splitting (HP:0003555)5.26538247
17Muscle stiffness (HP:0003552)5.17088376
18Absent phalangeal crease (HP:0006109)5.05464509
19Deformed tarsal bones (HP:0008119)4.78780084
20Rhabdomyolysis (HP:0003201)4.68777574
21Hyporeflexia of lower limbs (HP:0002600)4.66427610
22Myotonia (HP:0002486)4.50414602
23EMG: myopathic abnormalities (HP:0003458)4.42516752
24Increased connective tissue (HP:0009025)4.39255710
25Abnormal finger flexion creases (HP:0006143)4.23621656
26Abnormality of the calf musculature (HP:0001430)4.02857478
27Malignant hyperthermia (HP:0002047)3.75962441
28Abnormality of skeletal muscle fiber size (HP:0012084)3.67096889
29Subaortic stenosis (HP:0001682)3.63211203
30Abnormality of the left ventricular outflow tract (HP:0011103)3.63211203
31Rimmed vacuoles (HP:0003805)3.53919868
32Pelvic girdle muscle weakness (HP:0003749)3.52141398
33Shoulder girdle muscle weakness (HP:0003547)3.51877204
34Difficulty climbing stairs (HP:0003551)3.47545017
35Abnormality of the musculature of the pelvis (HP:0001469)3.39065664
36Abnormality of the hip-girdle musculature (HP:0001445)3.39065664
37Increased variability in muscle fiber diameter (HP:0003557)3.36986637
38Hyperkalemia (HP:0002153)3.35488367
39Neck muscle weakness (HP:0000467)3.29974607
40Areflexia of lower limbs (HP:0002522)3.19998059
41Abnormality of the calcaneus (HP:0008364)3.19496762
42Frequent falls (HP:0002359)2.98544850
43Paralysis (HP:0003470)2.94060504
44Asymmetric septal hypertrophy (HP:0001670)2.78107794
45Bundle branch block (HP:0011710)2.68407387
46Abnormality of the neuromuscular junction (HP:0003398)2.68108144
47Fatigable weakness (HP:0003473)2.68108144
48Muscular dystrophy (HP:0003560)2.42972954
49EMG: neuropathic changes (HP:0003445)2.41057081
50Hypoplastic ischia (HP:0003175)2.39980356
51Sudden death (HP:0001699)2.38243875
52Slender build (HP:0001533)2.34879404
53Nonprogressive disorder (HP:0003680)2.34417920
54Dilated cardiomyopathy (HP:0001644)2.33722558
55Distal lower limb muscle weakness (HP:0009053)2.32752874
56Limb-girdle muscle weakness (HP:0003325)2.31377518
57Proximal amyotrophy (HP:0007126)2.19061082
58Abnormality of the ischium (HP:0003174)2.08876688
59Abnormality of the shoulder girdle musculature (HP:0001435)2.08188013
60Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.06237672
61Ulnar deviation of finger (HP:0009465)2.04061256
62Generalized muscle weakness (HP:0003324)2.03964956
63Facial diplegia (HP:0001349)2.01762970
64Metatarsus adductus (HP:0001840)2.00323981
65Increased intramyocellular lipid droplets (HP:0012240)1.95519493
66Bulbar palsy (HP:0001283)1.95016440
67Lipoatrophy (HP:0100578)1.94919044
68Mildly elevated creatine phosphokinase (HP:0008180)1.94496266
69Gowers sign (HP:0003391)1.91751988
70Scapular winging (HP:0003691)1.90132106
71Distal lower limb amyotrophy (HP:0008944)1.88994970
72Achilles tendon contracture (HP:0001771)1.87739434
73Increased density of long bones (HP:0006392)1.87277737
74Abnormality of the foot musculature (HP:0001436)1.86461649
75Limb-girdle muscle atrophy (HP:0003797)1.83514137
76Increased muscle lipid content (HP:0009058)1.83507149
77Heart block (HP:0012722)1.82994884
78Stridor (HP:0010307)1.82942768
79Spinal rigidity (HP:0003306)1.82130484
80Hyperuricemia (HP:0002149)1.80019214
81Increased purine levels (HP:0004368)1.80019214
82Cholelithiasis (HP:0001081)1.79927601
83Type 2 muscle fiber atrophy (HP:0003554)1.77790079
84Short palpebral fissure (HP:0012745)1.76266104
85Respiratory insufficiency due to muscle weakness (HP:0002747)1.75219566
86Weak cry (HP:0001612)1.74562142
87Centrally nucleated skeletal muscle fibers (HP:0003687)1.72669159
88Abnormality of the Achilles tendon (HP:0005109)1.70859763
89Ragged-red muscle fibers (HP:0003200)1.69902865
90Abnormality of potassium homeostasis (HP:0011042)1.69562243
91Waddling gait (HP:0002515)1.69358936
92Progressive muscle weakness (HP:0003323)1.68313770
93Foot dorsiflexor weakness (HP:0009027)1.66253346
94Gout (HP:0001997)1.65791801
95Tarsal synostosis (HP:0008368)1.63426726
96Abnormal atrioventricular conduction (HP:0005150)1.62622484
97Muscle fiber atrophy (HP:0100295)1.60503779
98Oligomenorrhea (HP:0000876)1.59470281
99Abnormal gallbladder morphology (HP:0012437)1.59329441
100Lower limb amyotrophy (HP:0007210)1.58414621
101Ulnar deviation of the hand or of fingers of the hand (HP:0001193)1.58275263
102Insulin-resistant diabetes mellitus (HP:0000831)1.58266369
103Fetal akinesia sequence (HP:0001989)1.57720231
104Ventricular tachycardia (HP:0004756)1.56265005
105Long clavicles (HP:0000890)1.51484855
106Popliteal pterygium (HP:0009756)1.48926277
107Synostosis involving bones of the feet (HP:0009140)1.47481767
108Synostosis involving bones of the lower limbs (HP:0009138)1.47481767
109Toxemia of pregnancy (HP:0100603)1.46496588
110Exercise intolerance (HP:0003546)1.46096401
111Hypokalemia (HP:0002900)1.45865846
112Congenital hip dislocation (HP:0001374)1.44404210
113Acute necrotizing encephalopathy (HP:0006965)1.43896519
114Wrist flexion contracture (HP:0001239)1.43569835
115Abnormal mitochondria in muscle tissue (HP:0008316)1.41901022
116Adducted thumb (HP:0001181)1.40161316
117Hip contracture (HP:0003273)1.39266809
118Hyperglycinuria (HP:0003108)1.35796499
119Limited hip movement (HP:0008800)1.34505887
120Ventricular arrhythmia (HP:0004308)1.34324173
121Steppage gait (HP:0003376)1.32055638
122Neonatal hypotonia (HP:0001319)1.29546837
123Hepatic necrosis (HP:0002605)1.29135865

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN7.59157163
2TTN6.46528487
3PHKG25.94677275
4PHKG15.94677275
5NME14.61001102
6PIK3CG3.42708325
7MAP2K32.86791412
8NEK12.43004508
9MAP3K72.17819994
10PINK12.09974057
11DMPK1.94499639
12MAP2K41.84485499
13PDK41.84159467
14PDK31.84159467
15TRIB31.64013194
16PIK3CA1.57859544
17MAPK121.57396635
18BCKDK1.53782854
19MAP2K61.41657752
20MUSK1.27637352
21LATS11.26210536
22PDK21.20629160
23MAP3K61.09702337
24PRKAA21.03206760
25TAOK10.98483164
26NEK90.97870183
27PRKAA10.96414191
28LATS20.92087533
29CCNB10.89191937
30MAPKAPK30.88259700
31MARK10.86486054
32MAP3K30.82478461
33TAOK20.82303669
34STK240.78837719
35TRPM70.72272900
36BMPR1B0.70122556
37KSR20.68289504
38MAPK110.67965339
39VRK20.67504233
40ERBB30.64548874
41CDK190.63236970
42STK38L0.60664533
43MAP3K110.60383217
44TNIK0.55340926
45DAPK20.54315097
46CAMK2G0.52375839
47CAMK40.50463816
48AKT20.49834818
49EEF2K0.49140159
50ZAK0.49076884
51CAMK2A0.47549751
52FRK0.46407793
53CAMK10.44612984
54CAMK2D0.42890058
55NUAK10.39788231
56PKN20.39396807
57OXSR10.38561625
58RIPK10.38000914
59MAP3K50.37419607
60WNK30.37194177
61MAP4K20.36526214
62EPHB10.35627218
63ILK0.35051240
64SIK10.32791596
65MAP3K10.32621186
66SGK10.31477514
67LIMK10.30977543
68MOS0.30646902
69CAMK2B0.30456883
70PAK60.30039343
71INSRR0.28262843
72MAP3K130.28193983
73MAP3K40.27647734
74ADRBK20.27186209
75GRK10.26496832
76RPS6KA30.26071831
77ERBB40.25780373
78PRKACB0.25350726
79PTK60.25022643
80PRKG10.23401407
81PKN10.21932515
82STK30.21812563
83RPS6KB10.21506867
84NLK0.17566467
85PRKD30.17484596
86PRKACA0.15877620
87PLK40.15848965
88SGK20.15273625
89MAPK70.14818014
90MAPK40.14478385
91TYK20.14149776
92PDPK10.13810322
93CAMK1G0.13774769
94MAP3K100.13507441
95PRKD10.13480445
96STK160.13443207
97VRK10.12979392
98KSR10.12068896
99ROCK10.11808720
100TBK10.11619370
101RAF10.11421018
102MAP3K80.11289126
103TAF10.11028081
104PDK10.11015103
105PRKCQ0.10977646
106MAPKAPK50.10795395
107MAP2K10.10771142
108STK380.10637938
109MAP3K90.09997483
110MARK30.09846425
111PBK0.09679862
112CSNK1A10.09188752
113TNK20.09147237
114RPS6KA10.09121345
115CDK80.08983291
116TIE10.08504455
117RPS6KA60.07703831
118MAPK100.07633929
119CSNK1D0.07115848
120TGFBR10.06732307
121RET0.06192571
122GSK3B0.05889339
123STK110.05483047
124SGK30.05388669
125BMX0.05130400
126PRKCA0.04975280
127TSSK60.04903846
128JAK20.04852986
129MAP2K20.04755974
130ADRBK10.04284534
131PNCK0.04019965
132MTOR0.03631790
133BRAF0.00887394
134MAPK130.00112106
135PRKACG0.00082117
136DYRK1B-0.0244048
137RPS6KB2-0.0229549
138LRRK2-0.0226962
139MAPK9-0.0199290
140PRKDC-0.0172647
141ABL2-0.0156822
142MAPK8-0.0075579

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000204.09729360
2Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054104.09506330
3Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054123.63220324
42-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.27139221
5Cardiac muscle contraction_Homo sapiens_hsa042603.23247413
6Starch and sucrose metabolism_Homo sapiens_hsa005003.17033192
7Dilated cardiomyopathy_Homo sapiens_hsa054143.13108639
8Circadian rhythm_Homo sapiens_hsa047103.04924978
9Glucagon signaling pathway_Homo sapiens_hsa049222.61123668
10Insulin signaling pathway_Homo sapiens_hsa049102.52435493
11Oxytocin signaling pathway_Homo sapiens_hsa049212.45073602
12Propanoate metabolism_Homo sapiens_hsa006402.30206687
13Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.22546792
14Insulin resistance_Homo sapiens_hsa049312.22517943
15Carbon metabolism_Homo sapiens_hsa012002.12302621
16Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.94366498
17Adipocytokine signaling pathway_Homo sapiens_hsa049201.85365137
18Galactose metabolism_Homo sapiens_hsa000521.85211531
19AMPK signaling pathway_Homo sapiens_hsa041521.84757286
20Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.77671703
21Calcium signaling pathway_Homo sapiens_hsa040201.73353980
22Nitrogen metabolism_Homo sapiens_hsa009101.60301188
23Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.59226821
24Fructose and mannose metabolism_Homo sapiens_hsa000511.58082093
25Biosynthesis of amino acids_Homo sapiens_hsa012301.55462665
26Arginine and proline metabolism_Homo sapiens_hsa003301.44703442
27Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.44586883
28Pyruvate metabolism_Homo sapiens_hsa006201.42393009
29Alzheimers disease_Homo sapiens_hsa050101.40580336
30Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.40374370
31Parkinsons disease_Homo sapiens_hsa050121.38961922
32Viral myocarditis_Homo sapiens_hsa054161.35267414
33Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.31216175
34GnRH signaling pathway_Homo sapiens_hsa049121.30495336
35Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.29234385
36Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.27054919
37Pentose phosphate pathway_Homo sapiens_hsa000301.25769095
38Tight junction_Homo sapiens_hsa045301.25074234
39cGMP-PKG signaling pathway_Homo sapiens_hsa040221.20945252
40Fatty acid degradation_Homo sapiens_hsa000711.20605373
41Vascular smooth muscle contraction_Homo sapiens_hsa042701.17192297
42FoxO signaling pathway_Homo sapiens_hsa040681.15365335
43Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.12547685
44Oxidative phosphorylation_Homo sapiens_hsa001901.09304439
45Tryptophan metabolism_Homo sapiens_hsa003801.09092016
46Longevity regulating pathway - mammal_Homo sapiens_hsa042111.04816147
47mTOR signaling pathway_Homo sapiens_hsa041501.01564975
48Fatty acid elongation_Homo sapiens_hsa000621.01210457
49Gastric acid secretion_Homo sapiens_hsa049710.99203814
50Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.92619757
51VEGF signaling pathway_Homo sapiens_hsa043700.92242301
52Arginine biosynthesis_Homo sapiens_hsa002200.90596167
53Phototransduction_Homo sapiens_hsa047440.90302971
54Focal adhesion_Homo sapiens_hsa045100.90235083
55Central carbon metabolism in cancer_Homo sapiens_hsa052300.88866883
56Fatty acid metabolism_Homo sapiens_hsa012120.79512123
57MAPK signaling pathway_Homo sapiens_hsa040100.77650146
58HIF-1 signaling pathway_Homo sapiens_hsa040660.74041696
59Renin secretion_Homo sapiens_hsa049240.60425064
60beta-Alanine metabolism_Homo sapiens_hsa004100.59052850
61Platelet activation_Homo sapiens_hsa046110.58895884
62Huntingtons disease_Homo sapiens_hsa050160.55755902
63Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.55692825
64Fatty acid biosynthesis_Homo sapiens_hsa000610.55338584
65Type II diabetes mellitus_Homo sapiens_hsa049300.48174214
66Long-term depression_Homo sapiens_hsa047300.47642577
67Renal cell carcinoma_Homo sapiens_hsa052110.47253889
68Regulation of actin cytoskeleton_Homo sapiens_hsa048100.47204097
69Adherens junction_Homo sapiens_hsa045200.45875687
70Olfactory transduction_Homo sapiens_hsa047400.42542619
71Prolactin signaling pathway_Homo sapiens_hsa049170.37977731
72PPAR signaling pathway_Homo sapiens_hsa033200.37650373
73RNA polymerase_Homo sapiens_hsa030200.36818777
74Insulin secretion_Homo sapiens_hsa049110.36511277
75alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.36454259
76Leukocyte transendothelial migration_Homo sapiens_hsa046700.33139177
77Histidine metabolism_Homo sapiens_hsa003400.33034443
78Aldosterone synthesis and secretion_Homo sapiens_hsa049250.32649125
79Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.31346970
80Linoleic acid metabolism_Homo sapiens_hsa005910.31202760
81One carbon pool by folate_Homo sapiens_hsa006700.29191291
82Amoebiasis_Homo sapiens_hsa051460.27216629
83Dorso-ventral axis formation_Homo sapiens_hsa043200.26673352
84Butanoate metabolism_Homo sapiens_hsa006500.25365133
85Proteasome_Homo sapiens_hsa030500.24825041
86Glycerophospholipid metabolism_Homo sapiens_hsa005640.24541063
87Proteoglycans in cancer_Homo sapiens_hsa052050.24188930
88RNA degradation_Homo sapiens_hsa030180.22563519
89Purine metabolism_Homo sapiens_hsa002300.21578648
90Ovarian steroidogenesis_Homo sapiens_hsa049130.21248418
91Tyrosine metabolism_Homo sapiens_hsa003500.20934422
92Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.20395186
93Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.20250891
94AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.19752457
95Cholinergic synapse_Homo sapiens_hsa047250.19652942
96Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.19124459
97Phenylalanine metabolism_Homo sapiens_hsa003600.18931192
98Cysteine and methionine metabolism_Homo sapiens_hsa002700.17968881
99Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.17891510
100Ribosome_Homo sapiens_hsa030100.17874195
101Maturity onset diabetes of the young_Homo sapiens_hsa049500.17530427
102Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.16754607
103Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.15820286
104Nucleotide excision repair_Homo sapiens_hsa034200.15612048
105Long-term potentiation_Homo sapiens_hsa047200.14815926
106Glutathione metabolism_Homo sapiens_hsa004800.13833030
107Folate biosynthesis_Homo sapiens_hsa007900.13688636
108Amphetamine addiction_Homo sapiens_hsa050310.11914526
109Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.11722937
110Neurotrophin signaling pathway_Homo sapiens_hsa047220.11585021
111Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.11526180
112cAMP signaling pathway_Homo sapiens_hsa040240.11487863
113Basal transcription factors_Homo sapiens_hsa030220.11436416
114Sulfur relay system_Homo sapiens_hsa041220.11163916
115Oocyte meiosis_Homo sapiens_hsa041140.10121192
116Lysine degradation_Homo sapiens_hsa003100.09599770
117Salivary secretion_Homo sapiens_hsa049700.09093935
118Peroxisome_Homo sapiens_hsa041460.07902437
119Metabolic pathways_Homo sapiens_hsa011000.07792015
120Regulation of autophagy_Homo sapiens_hsa041400.07657561
121Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.07453011
122Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.07403341
123Thyroid cancer_Homo sapiens_hsa052160.07337161
124Circadian entrainment_Homo sapiens_hsa047130.06456661

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