MYSM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic sister chromatid cohesion (GO:0007064)5.74283335
2pre-miRNA processing (GO:0031054)5.62753733
3regulation of RNA export from nucleus (GO:0046831)4.79791666
4negative regulation of translation involved in gene silencing by miRNA (GO:0035278)4.66622188
5negative regulation of translation, ncRNA-mediated (GO:0040033)4.66622188
6regulation of translation, ncRNA-mediated (GO:0045974)4.66622188
7cytoplasmic mRNA processing body assembly (GO:0033962)4.06928921
8definitive hemopoiesis (GO:0060216)4.02369897
9negative regulation of DNA repair (GO:0045738)4.01955634
10regulation of nucleobase-containing compound transport (GO:0032239)3.89900123
11protein prenylation (GO:0018342)3.86645247
12prenylation (GO:0097354)3.86645247
13negative regulation of histone methylation (GO:0031061)3.77368845
14regulation of centriole replication (GO:0046599)3.72267913
15double-strand break repair via nonhomologous end joining (GO:0006303)3.68975387
16non-recombinational repair (GO:0000726)3.68975387
17positive regulation of histone H3-K4 methylation (GO:0051571)3.66927404
18negative regulation of DNA-dependent DNA replication (GO:2000104)3.64792930
19* monoubiquitinated protein deubiquitination (GO:0035520)3.61919886
20regulation of histone H3-K27 methylation (GO:0061085)3.61811924
21DNA duplex unwinding (GO:0032508)3.53303952
22regulation of histone H3-K9 methylation (GO:0051570)3.46594008
23DNA geometric change (GO:0032392)3.44774593
24positive regulation of cell cycle checkpoint (GO:1901978)3.43432175
25replication fork processing (GO:0031297)3.35056556
26N-terminal protein amino acid acetylation (GO:0006474)3.29288991
27histone H4-K16 acetylation (GO:0043984)3.29101068
28regulation of histone methylation (GO:0031060)3.27999156
29protein localization to kinetochore (GO:0034501)3.26974594
30peptidyl-lysine trimethylation (GO:0018023)3.24896321
31DNA topological change (GO:0006265)3.24019323
32histone lysine demethylation (GO:0070076)3.22974943
33embryonic process involved in female pregnancy (GO:0060136)3.22901370
34regulation of histone H3-K4 methylation (GO:0051569)3.21305846
35vitamin transmembrane transport (GO:0035461)3.20501911
36sister chromatid segregation (GO:0000819)3.19501078
37mitotic G2/M transition checkpoint (GO:0044818)3.14515249
38histone demethylation (GO:0016577)3.11760333
39maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.11572619
40regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.08807823
41regulation of mitotic spindle checkpoint (GO:1903504)3.08807823
42mitotic nuclear envelope disassembly (GO:0007077)3.08076025
43negative regulation of mast cell activation (GO:0033004)3.07844151
44negative regulation of fibroblast apoptotic process (GO:2000270)3.03954226
45positive regulation of histone methylation (GO:0031062)3.03677608
46regulation of DNA damage checkpoint (GO:2000001)3.01889057
47histone H3-K9 demethylation (GO:0033169)3.01414383
48negative regulation of DNA recombination (GO:0045910)3.00688648
49NLS-bearing protein import into nucleus (GO:0006607)3.00417058
50histone-serine phosphorylation (GO:0035404)2.99790996
51membrane disassembly (GO:0030397)2.99467372
52nuclear envelope disassembly (GO:0051081)2.99467372
53regulation of centrosome duplication (GO:0010824)2.98852481
54protein localization to chromosome, centromeric region (GO:0071459)2.98244955
55histone H3-K4 trimethylation (GO:0080182)2.97317937
56histone mRNA catabolic process (GO:0071044)2.96393526
57pore complex assembly (GO:0046931)2.96296056
58heterochromatin organization (GO:0070828)2.95909384
59kinetochore organization (GO:0051383)2.95452846
60regulation of chromatin silencing (GO:0031935)2.94568424
61DNA synthesis involved in DNA repair (GO:0000731)2.92451885
62nuclear pore complex assembly (GO:0051292)2.92034482
63meiotic chromosome segregation (GO:0045132)2.91401216
64regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.90036011
65regulation of mitotic metaphase/anaphase transition (GO:0030071)2.90036011
66kinetochore assembly (GO:0051382)2.89441318
67regulation of mitotic sister chromatid separation (GO:0010965)2.88049357
68regulation of mitotic sister chromatid segregation (GO:0033047)2.88049357
69regulation of sister chromatid segregation (GO:0033045)2.88049357
70positive regulation of mitotic sister chromatid separation (GO:1901970)2.88006269
71positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.88006269
72positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.88006269
73intra-S DNA damage checkpoint (GO:0031573)2.87429678
74positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.85462004
75regulation of hexokinase activity (GO:1903299)2.84851053
76regulation of glucokinase activity (GO:0033131)2.84851053
77cell differentiation involved in metanephros development (GO:0072202)2.83623912
78regulation of centrosome cycle (GO:0046605)2.82724910
79nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.80345839
80mitotic G2 DNA damage checkpoint (GO:0007095)2.79503821
81negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.79188821
82negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.79188821
83negative regulation of mitotic sister chromatid segregation (GO:0033048)2.79188821
84negative regulation of mitotic sister chromatid separation (GO:2000816)2.79188821
85negative regulation of sister chromatid segregation (GO:0033046)2.79188821
86negative regulation of chromosome segregation (GO:0051985)2.78949997
87mRNA transport (GO:0051028)2.78803946
88positive regulation of SMAD protein import into nucleus (GO:0060391)2.76319792
89mitotic sister chromatid segregation (GO:0000070)2.73699270
90mitotic spindle checkpoint (GO:0071174)2.73536214
91DNA conformation change (GO:0071103)2.72779658
92positive regulation of dendritic spine morphogenesis (GO:0061003)2.71782437
93regulation of sister chromatid cohesion (GO:0007063)2.71421344
94interkinetic nuclear migration (GO:0022027)2.71216764
95positive regulation of protein homodimerization activity (GO:0090073)2.70710064
96protein K48-linked deubiquitination (GO:0071108)2.70084715
97mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.69324356
98positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.69324356
99regulation of helicase activity (GO:0051095)2.69225257
100protein demethylation (GO:0006482)2.68664518
101protein dealkylation (GO:0008214)2.68664518
102regulation of DNA endoreduplication (GO:0032875)2.67826558
103nucleus organization (GO:0006997)2.66229616
104poly(A)+ mRNA export from nucleus (GO:0016973)2.65245969
105regulation of Rac protein signal transduction (GO:0035020)2.64559146
106regulation of nuclear cell cycle DNA replication (GO:0033262)2.64110013
107negative regulation of dendrite morphogenesis (GO:0050774)2.63913277
108DNA strand renaturation (GO:0000733)2.63889340
109DNA ligation (GO:0006266)2.63819304
110protein K6-linked ubiquitination (GO:0085020)2.63541680
111DNA-dependent DNA replication (GO:0006261)2.61338381
112interferon-gamma production (GO:0032609)2.60202483
113nuclear pore organization (GO:0006999)2.58616142
114positive regulation of cellular amide metabolic process (GO:0034250)2.57126426
115replicative senescence (GO:0090399)2.54837257
116response to pheromone (GO:0019236)2.54703104
117sister chromatid cohesion (GO:0007062)2.53867967
118viral protein processing (GO:0019082)2.53353391
119CENP-A containing nucleosome assembly (GO:0034080)2.51042609
120GMP metabolic process (GO:0046037)2.50521748
121snRNA processing (GO:0016180)2.48244202
122termination of RNA polymerase I transcription (GO:0006363)2.47665043
123regulation of germinal center formation (GO:0002634)2.46924447
124reciprocal meiotic recombination (GO:0007131)2.46739431
125reciprocal DNA recombination (GO:0035825)2.46739431
126microtubule depolymerization (GO:0007019)2.45857136
127negative regulation of keratinocyte proliferation (GO:0010839)2.45574853
128transcription elongation from RNA polymerase I promoter (GO:0006362)2.45207320
129resolution of meiotic recombination intermediates (GO:0000712)2.44886428
130purine nucleobase biosynthetic process (GO:0009113)2.42328776
131dendritic cell chemotaxis (GO:0002407)2.41592562
132histone H3-K36 demethylation (GO:0070544)2.38581984
133cellular response to gamma radiation (GO:0071480)2.38196567
134mitotic metaphase plate congression (GO:0007080)2.35295290
135fat-soluble vitamin biosynthetic process (GO:0042362)2.34909448
136regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.34879985
137mRNA splice site selection (GO:0006376)2.34796665
138DNA double-strand break processing (GO:0000729)2.34207410
139preassembly of GPI anchor in ER membrane (GO:0016254)2.32530192
140mesenchymal cell differentiation involved in kidney development (GO:0072161)2.31245868
141mesenchymal cell differentiation involved in renal system development (GO:2001012)2.31245868
142startle response (GO:0001964)2.30895359
143regulation of establishment or maintenance of cell polarity (GO:0032878)2.29697973
144metaphase plate congression (GO:0051310)2.29065648
145smooth muscle tissue development (GO:0048745)2.28568279
146chromatin remodeling at centromere (GO:0031055)2.27690326
147sprouting angiogenesis (GO:0002040)2.26561979
148centriole replication (GO:0007099)2.26299897
149microtubule anchoring (GO:0034453)2.25886203
150transcription initiation from RNA polymerase I promoter (GO:0006361)2.25820621
151maturation of 5.8S rRNA (GO:0000460)2.25544524
152V(D)J recombination (GO:0033151)2.24101356
153N-terminal protein amino acid modification (GO:0031365)2.22925579
154dendritic cell migration (GO:0036336)2.22543235
155transcription elongation from RNA polymerase III promoter (GO:0006385)2.22237663
156termination of RNA polymerase III transcription (GO:0006386)2.22237663
157rRNA methylation (GO:0031167)2.20577031
158centriole assembly (GO:0098534)2.19781532
159CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.19383502
160transcription from RNA polymerase III promoter (GO:0006383)2.19027727
161phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.18955812
162antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.17009898
163protein K11-linked deubiquitination (GO:0035871)2.16438014
164negative regulation of myoblast differentiation (GO:0045662)2.15962421
1657-methylguanosine mRNA capping (GO:0006370)2.15470276
1667-methylguanosine RNA capping (GO:0009452)2.13646584
167RNA capping (GO:0036260)2.13646584
168DNA replication-independent nucleosome organization (GO:0034724)2.12889615
169DNA replication-independent nucleosome assembly (GO:0006336)2.12889615
170regulation of telomere maintenance (GO:0032204)2.12655511
171DNA catabolic process, exonucleolytic (GO:0000738)2.10664562
172transcription from RNA polymerase I promoter (GO:0006360)2.10647887
173mannosylation (GO:0097502)2.10435875
174cyclic nucleotide catabolic process (GO:0009214)2.10007198
175mitotic recombination (GO:0006312)2.09390992
176spindle checkpoint (GO:0031577)2.08666081
177histone mRNA metabolic process (GO:0008334)2.08437070
178histone H3-K4 methylation (GO:0051568)2.07717329

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.14683506
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.38255848
3HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.14621232
4EGR1_19374776_ChIP-ChIP_THP-1_Human2.96396405
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.63828525
6FOXM1_23109430_ChIP-Seq_U2OS_Human2.54275512
7GBX2_23144817_ChIP-Seq_PC3_Human2.53088406
8POU3F2_20337985_ChIP-ChIP_501MEL_Human2.51928620
9FLI1_27457419_Chip-Seq_LIVER_Mouse2.50084914
10TP63_19390658_ChIP-ChIP_HaCaT_Human2.31834176
11PCGF2_27294783_Chip-Seq_ESCs_Mouse2.29865591
12SALL1_21062744_ChIP-ChIP_HESCs_Human2.18652321
13ZFP57_27257070_Chip-Seq_ESCs_Mouse2.13129031
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.12512541
15CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.09390134
16* EWS_26573619_Chip-Seq_HEK293_Human2.09085646
17ELF1_17652178_ChIP-ChIP_JURKAT_Human2.08201086
18* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.99878642
19FUS_26573619_Chip-Seq_HEK293_Human1.97758447
20WT1_19549856_ChIP-ChIP_CCG9911_Human1.91194680
21MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.88131281
22E2F4_17652178_ChIP-ChIP_JURKAT_Human1.85123930
23RBPJ_22232070_ChIP-Seq_NCS_Mouse1.84947686
24STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.82682272
25SUZ12_27294783_Chip-Seq_NPCs_Mouse1.81862498
26KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.81483433
27AR_21909140_ChIP-Seq_LNCAP_Human1.81090968
28ELK1_19687146_ChIP-ChIP_HELA_Human1.78128114
29SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.77527829
30POU5F1_16153702_ChIP-ChIP_HESCs_Human1.77485160
31SMAD_19615063_ChIP-ChIP_OVARY_Human1.73910492
32NFE2_27457419_Chip-Seq_LIVER_Mouse1.72898097
33NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.72414390
34E2F1_21310950_ChIP-Seq_MCF-7_Human1.69049035
35YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.68443483
36* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.68414199
37IRF1_19129219_ChIP-ChIP_H3396_Human1.67826020
38GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.67137316
39PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.67042192
40PCGF2_27294783_Chip-Seq_NPCs_Mouse1.64173856
41NOTCH1_21737748_ChIP-Seq_TLL_Human1.63786947
42NANOG_18555785_Chip-Seq_ESCs_Mouse1.63472296
43P300_19829295_ChIP-Seq_ESCs_Human1.63320317
44KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.59138986
45KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.59138986
46KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.59138986
47TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.57957213
48TAF15_26573619_Chip-Seq_HEK293_Human1.56033848
49E2F1_18555785_Chip-Seq_ESCs_Mouse1.55569807
50EZH2_27294783_Chip-Seq_NPCs_Mouse1.54856591
51SUZ12_18555785_Chip-Seq_ESCs_Mouse1.52735838
52IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.51053531
53STAT3_18555785_Chip-Seq_ESCs_Mouse1.49149412
54EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.49008183
55PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.47520047
56EST1_17652178_ChIP-ChIP_JURKAT_Human1.44472604
57SALL4_18804426_ChIP-ChIP_XEN_Mouse1.44003203
58AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.43595135
59P53_22387025_ChIP-Seq_ESCs_Mouse1.43105753
60TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.41916549
61NMYC_18555785_Chip-Seq_ESCs_Mouse1.41449066
62P300_18555785_Chip-Seq_ESCs_Mouse1.37828602
63HOXB4_20404135_ChIP-ChIP_EML_Mouse1.37727366
64EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.37448613
65DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.37030309
66SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.35717057
67HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.35048973
68TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.34522309
69HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.33567040
70IGF1R_20145208_ChIP-Seq_DFB_Human1.32765927
71MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.32726904
72CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.31521342
73IRF8_22096565_ChIP-ChIP_GC-B_Human1.31035073
74SOX2_18555785_Chip-Seq_ESCs_Mouse1.30977541
75CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.30906217
76TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.30119898
77CMYC_18555785_Chip-Seq_ESCs_Mouse1.30090144
78GABP_17652178_ChIP-ChIP_JURKAT_Human1.29406916
79RUNX1_27457419_Chip-Seq_LIVER_Mouse1.28381042
80RNF2_27304074_Chip-Seq_NSC_Mouse1.28023814
81GATA1_22025678_ChIP-Seq_K562_Human1.26809658
82OCT4_18555785_Chip-Seq_ESCs_Mouse1.25891477
83VDR_23849224_ChIP-Seq_CD4+_Human1.25286771
84STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.25095792
85STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.24928521
86BP1_19119308_ChIP-ChIP_Hs578T_Human1.23795440
87SRF_21415370_ChIP-Seq_HL-1_Mouse1.23506812
88ZFX_18555785_Chip-Seq_ESCs_Mouse1.22961401
89SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.22851615
90RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.21375908
91FOXM1_26456572_ChIP-Seq_MCF-7_Human1.19779192
92AR_21572438_ChIP-Seq_LNCaP_Human1.18759972
93TP53_16413492_ChIP-PET_HCT116_Human1.18632345
94PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.17571723
95ER_23166858_ChIP-Seq_MCF-7_Human1.16435969
96SMAD1_18555785_Chip-Seq_ESCs_Mouse1.16185994
97MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.14719966
98* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.13856820
99FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.13665534
100PU1_27457419_Chip-Seq_LIVER_Mouse1.12852240
101ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.12536713
102PADI4_21655091_ChIP-ChIP_MCF-7_Human1.12369972
103MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.11957852
104KLF4_18555785_Chip-Seq_ESCs_Mouse1.11520883
105RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.11461384
106OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.10673619
107MYCN_18555785_ChIP-Seq_MESCs_Mouse1.10639234
108FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.10625671
109* SMAD4_21799915_ChIP-Seq_A2780_Human1.10425272
110BMI1_23680149_ChIP-Seq_NPCS_Mouse1.09821208
111FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.09515378
112PIAS1_25552417_ChIP-Seq_VCAP_Human1.08642265
113ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.08322206
114FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.07847711
115CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.07253781
116LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07167622
117* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.07135383
118CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.06177170
119CTCF_18555785_Chip-Seq_ESCs_Mouse1.05562051
120* TCF4_23295773_ChIP-Seq_U87_Human1.04490604
121FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.04463606
122ZNF217_24962896_ChIP-Seq_MCF-7_Human1.04357733
123CRX_20693478_ChIP-Seq_RETINA_Mouse1.02729481
124* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.02187418
125ESRRB_18555785_Chip-Seq_ESCs_Mouse1.01866985
126CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.00863706
127* STAT3_23295773_ChIP-Seq_U87_Human1.00545317
128FOXP3_21729870_ChIP-Seq_TREG_Human0.99892621
129POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.99752700
130TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99752700
131SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98391942
132* SMAD3_21741376_ChIP-Seq_EPCs_Human0.97264956
133TCF4_18268006_ChIP-ChIP_LS174T_Human0.95552486
134CHD1_26751641_Chip-Seq_LNCaP_Human0.95003080
135CDX2_19796622_ChIP-Seq_MESCs_Mouse0.94670366
136CTNNB1_20460455_ChIP-Seq_HCT116_Human0.93078867
137ZNF274_21170338_ChIP-Seq_K562_Hela0.91823684
138* BRD4_25478319_ChIP-Seq_HGPS_Human0.91281384
139STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.90046278
140NANOG_16153702_ChIP-ChIP_HESCs_Human0.89690604
141OCT4_21477851_ChIP-Seq_ESCs_Mouse0.87797264
142TBX3_20139965_ChIP-Seq_ESCs_Mouse0.87789246
143TBX3_20139965_ChIP-Seq_MESCs_Mouse0.87414973
144MYB_26560356_Chip-Seq_TH2_Human0.86631227

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode3.25194141
2MP0010352_gastrointestinal_tract_polyps3.18737916
3MP0008058_abnormal_DNA_repair3.13170314
4MP0003787_abnormal_imprinting3.07397108
5MP0000015_abnormal_ear_pigmentation3.02371273
6MP0001188_hyperpigmentation2.80119329
7MP0004957_abnormal_blastocyst_morpholog2.73043292
8MP0002009_preneoplasia2.58927171
9MP0000569_abnormal_digit_pigmentation2.52707358
10MP0008877_abnormal_DNA_methylation2.47674422
11MP0008057_abnormal_DNA_replication2.44420103
12MP0000566_synostosis2.38808754
13MP0010094_abnormal_chromosome_stability2.36465376
14MP0010307_abnormal_tumor_latency2.22605781
15MP0008007_abnormal_cellular_replicative2.18221894
16MP0002396_abnormal_hematopoietic_system2.05050703
17MP0005671_abnormal_response_to1.95621344
18MP0005409_darkened_coat_color1.95189790
19MP0009672_abnormal_birth_weight1.87481037
20MP0003984_embryonic_growth_retardation1.87092362
21MP0002088_abnormal_embryonic_growth/wei1.84251464
22MP0001672_abnormal_embryogenesis/_devel1.82484275
23MP0005380_embryogenesis_phenotype1.82484275
24MP0009697_abnormal_copulation1.80139015
25MP0005075_abnormal_melanosome_morpholog1.79354148
26MP0003121_genomic_imprinting1.79051014
27MP0003941_abnormal_skin_development1.77523320
28MP0002095_abnormal_skin_pigmentation1.77255237
29MP0003943_abnormal_hepatobiliary_system1.76819748
30MP0001730_embryonic_growth_arrest1.75252625
31MP0001986_abnormal_taste_sensitivity1.74114402
32MP0010386_abnormal_urinary_bladder1.71962286
33MP0009703_decreased_birth_body1.69966493
34MP0003136_yellow_coat_color1.68368633
35MP0000350_abnormal_cell_proliferation1.67655063
36MP0004264_abnormal_extraembryonic_tissu1.64903885
37MP0005171_absent_coat_pigmentation1.62440274
38MP0003693_abnormal_embryo_hatching1.59192317
39MP0002938_white_spotting1.58864303
40MP0000516_abnormal_urinary_system1.56106367
41MP0005367_renal/urinary_system_phenotyp1.56106367
42MP0002254_reproductive_system_inflammat1.55884872
43MP0004197_abnormal_fetal_growth/weight/1.55714642
44MP0001697_abnormal_embryo_size1.55244229
45MP0008260_abnormal_autophagy1.54833035
46MP0005379_endocrine/exocrine_gland_phen1.51386788
47MP0002086_abnormal_extraembryonic_tissu1.51169628
48MP0003111_abnormal_nucleus_morphology1.51034969
49MP0008961_abnormal_basal_metabolism1.50899929
50MP0002102_abnormal_ear_morphology1.49546802
51MP0005174_abnormal_tail_pigmentation1.48438960
52MP0002084_abnormal_developmental_patter1.47292392
53MP0005076_abnormal_cell_differentiation1.46756136
54MP0001835_abnormal_antigen_presentation1.46685758
55MP0008932_abnormal_embryonic_tissue1.46165109
56MP0003077_abnormal_cell_cycle1.46145208
57MP0003786_premature_aging1.45641534
58MP0003763_abnormal_thymus_physiology1.43996515
59MP0003890_abnormal_embryonic-extraembry1.41088819
60MP0003221_abnormal_cardiomyocyte_apopto1.35714047
61MP0002006_tumorigenesis1.35706657
62MP0002163_abnormal_gland_morphology1.35500634
63MP0003724_increased_susceptibility_to1.35321005
64MP0002277_abnormal_respiratory_mucosa1.35083532
65MP0004808_abnormal_hematopoietic_stem1.30163100
66MP0005646_abnormal_pituitary_gland1.30133459
67MP0002132_abnormal_respiratory_system1.27667295
68MP0002085_abnormal_embryonic_tissue1.23950357
69MP0005377_hearing/vestibular/ear_phenot1.20409789
70MP0003878_abnormal_ear_physiology1.20409789
71MP0001873_stomach_inflammation1.19213883
72MP0002166_altered_tumor_susceptibility1.16914996
73MP0003123_paternal_imprinting1.14550743
74MP0002160_abnormal_reproductive_system1.14320600
75MP0000372_irregular_coat_pigmentation1.12543944
76MP0001186_pigmentation_phenotype1.12286051
77MP0002177_abnormal_outer_ear1.12124879
78MP0001119_abnormal_female_reproductive1.11272979
79MP0002876_abnormal_thyroid_physiology1.09857063
80MP0002080_prenatal_lethality1.09746007
81MP0005187_abnormal_penis_morphology1.07223555
82MP0000428_abnormal_craniofacial_morphol1.06561361
83MP0003718_maternal_effect1.04270314
84MP0003656_abnormal_erythrocyte_physiolo1.04128890
85MP0001286_abnormal_eye_development1.03459548
86MP0005389_reproductive_system_phenotype1.00529126
87MP0003183_abnormal_peptide_metabolism0.98757784
88MP0004381_abnormal_hair_follicle0.98651838
89MP0005310_abnormal_salivary_gland0.98552033
90MP0008995_early_reproductive_senescence0.98410882
91MP0001800_abnormal_humoral_immune0.98039865
92MP0002697_abnormal_eye_size0.97386744
93MP0002398_abnormal_bone_marrow0.96889673
94MP0001293_anophthalmia0.96744700
95MP0004782_abnormal_surfactant_physiolog0.95065957
96MP0005621_abnormal_cell_physiology0.94478584
97MP0002420_abnormal_adaptive_immunity0.93879118
98MP0000313_abnormal_cell_death0.92786482
99MP0000681_abnormal_thyroid_gland0.92225318
100MP0002925_abnormal_cardiovascular_devel0.92052310
101MP0002452_abnormal_antigen_presenting0.91796756
102MP0001819_abnormal_immune_cell0.91525643
103MP0010630_abnormal_cardiac_muscle0.91322509
104MP0003122_maternal_imprinting0.90970308
105MP0005408_hypopigmentation0.89570061
106MP0000613_abnormal_salivary_gland0.89486516
107MP0002210_abnormal_sex_determination0.87672821
108MP0001915_intracranial_hemorrhage0.86694455
109MP0004084_abnormal_cardiac_muscle0.86035544
110MP0000432_abnormal_head_morphology0.85037834
111MP0005645_abnormal_hypothalamus_physiol0.84878027
112MP0000703_abnormal_thymus_morphology0.84841889
113MP0002075_abnormal_coat/hair_pigmentati0.83099698
114MP0003172_abnormal_lysosome_physiology0.81792689
115MP0002723_abnormal_immune_serum0.80093225
116MP0002638_abnormal_pupillary_reflex0.80040262
117MP0001177_atelectasis0.79549716
118MP0000716_abnormal_immune_system0.79136629
119MP0010234_abnormal_vibrissa_follicle0.78755963
120MP0001919_abnormal_reproductive_system0.78719445
121MP0003868_abnormal_feces_composition0.78479017
122MP0003935_abnormal_craniofacial_develop0.78183529
123MP0005384_cellular_phenotype0.77425105
124MP0002148_abnormal_hypersensitivity_rea0.77228760
125MP0005387_immune_system_phenotype0.76976581
126MP0001790_abnormal_immune_system0.76976581
127MP0001905_abnormal_dopamine_level0.76903443
128MP0003567_abnormal_fetal_cardiomyocyte0.76675620
129MP0004147_increased_porphyrin_level0.76563206
130MP0010678_abnormal_skin_adnexa0.75697299
131MP0000371_diluted_coat_color0.73215949
132MP0004185_abnormal_adipocyte_glucose0.72981470
133MP0004233_abnormal_muscle_weight0.72503397
134MP0000689_abnormal_spleen_morphology0.71180609
135MP0009333_abnormal_splenocyte_physiolog0.71125373
136MP0004134_abnormal_chest_morphology0.70858348
137MP0002429_abnormal_blood_cell0.70126980
138MP0003937_abnormal_limbs/digits/tail_de0.69761634
139MP0005000_abnormal_immune_tolerance0.69228516
140MP0003828_pulmonary_edema0.69099267
141MP0005647_abnormal_sex_gland0.69055506
142MP0002722_abnormal_immune_system0.68417763
143MP0000266_abnormal_heart_morphology0.67950646
144MP0002751_abnormal_autonomic_nervous0.67389910
145MP0002877_abnormal_melanocyte_morpholog0.66670005
146MP0002419_abnormal_innate_immunity0.66233841
147MP0001145_abnormal_male_reproductive0.65781914
148MP0000631_abnormal_neuroendocrine_gland0.65731670
149MP0001299_abnormal_eye_distance/0.65385292
150MP0000653_abnormal_sex_gland0.65272738
151MP0002019_abnormal_tumor_incidence0.64674252
152MP0001784_abnormal_fluid_regulation0.63759791
153MP0003115_abnormal_respiratory_system0.63547735
154MP0005395_other_phenotype0.62987803
155MP0000383_abnormal_hair_follicle0.61920463
156MP0005220_abnormal_exocrine_pancreas0.60650964
157MP0009115_abnormal_fat_cell0.59666898
158MP0002092_abnormal_eye_morphology0.58138716
159MP0001929_abnormal_gametogenesis0.53999589
160MP0000647_abnormal_sebaceous_gland0.53483401
161MP0003861_abnormal_nervous_system0.52594316
162MP0001191_abnormal_skin_condition0.51779332

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.54525922
2Chromsome breakage (HP:0040012)4.29237079
3Hepatoblastoma (HP:0002884)3.60477302
4Rhabdomyosarcoma (HP:0002859)3.34664140
5Birth length less than 3rd percentile (HP:0003561)3.14281156
6Abnormal hair whorl (HP:0010721)3.11179913
7Medulloblastoma (HP:0002885)3.02065015
8Thyroid carcinoma (HP:0002890)3.00616119
9Pancreatic fibrosis (HP:0100732)2.98027360
10Ectopic kidney (HP:0000086)2.96588690
11Volvulus (HP:0002580)2.96398501
12Biliary tract neoplasm (HP:0100574)2.86690610
13True hermaphroditism (HP:0010459)2.80408006
14Intestinal atresia (HP:0011100)2.76819654
15Gastrointestinal carcinoma (HP:0002672)2.73460104
16Malignant gastrointestinal tract tumors (HP:0006749)2.73460104
17Prostate neoplasm (HP:0100787)2.69158077
18Abnormality of chromosome stability (HP:0003220)2.68929984
19Aqueductal stenosis (HP:0002410)2.68620140
20Curly hair (HP:0002212)2.66670174
21Neoplasm of the small intestine (HP:0100833)2.65046006
22Abnormality of the astrocytes (HP:0100707)2.62781166
23Astrocytoma (HP:0009592)2.62781166
24Glioma (HP:0009733)2.62660823
25Transitional cell carcinoma of the bladder (HP:0006740)2.61383587
26Anal stenosis (HP:0002025)2.57308239
27Abnormality of incisor morphology (HP:0011063)2.57214353
28Neoplasm of the adrenal cortex (HP:0100641)2.56245915
29Hypoplastic labia majora (HP:0000059)2.56177149
30Aplasia/Hypoplasia of the uvula (HP:0010293)2.52759281
31Acute lymphatic leukemia (HP:0006721)2.51986059
32Abnormality of the preputium (HP:0100587)2.51084149
33Acute myeloid leukemia (HP:0004808)2.50419870
34Meckel diverticulum (HP:0002245)2.48884282
35Neoplasm of striated muscle (HP:0009728)2.46377222
36Subacute progressive viral hepatitis (HP:0006572)2.43894614
37Colon cancer (HP:0003003)2.42398577
38Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.41184316
39Abnormality of the fingertips (HP:0001211)2.38615106
40Abnormality of the ileum (HP:0001549)2.37625977
41Bladder carcinoma (HP:0002862)2.37401483
42Bladder neoplasm (HP:0009725)2.37401483
43Febrile seizures (HP:0002373)2.36360519
44Type I transferrin isoform profile (HP:0003642)2.35724831
45Aplasia/Hypoplasia of the fovea (HP:0008060)2.34033129
46Hypoplasia of the fovea (HP:0007750)2.34033129
47Abnormality of the labia majora (HP:0012881)2.33478160
48Heterotopia (HP:0002282)2.32607347
49Submucous cleft hard palate (HP:0000176)2.32445928
50Ependymoma (HP:0002888)2.30651384
51Optic neuritis (HP:0100653)2.24518567
52Retrobulbar optic neuritis (HP:0100654)2.24518567
53Leiomyosarcoma (HP:0100243)2.24444539
54Uterine leiomyosarcoma (HP:0002891)2.24444539
55Hypothermia (HP:0002045)2.23782812
56Diastasis recti (HP:0001540)2.23289723
57Overlapping toe (HP:0001845)2.23177190
58Nephroblastoma (Wilms tumor) (HP:0002667)2.22121142
59Long clavicles (HP:0000890)2.21690188
60Embryonal renal neoplasm (HP:0011794)2.17866829
61Low anterior hairline (HP:0000294)2.17369620
62Absent eyebrow (HP:0002223)2.15542891
63T lymphocytopenia (HP:0005403)2.13601249
64Neonatal hypoglycemia (HP:0001998)2.13024381
65Narrow palate (HP:0000189)2.12789354
66Gaze-evoked nystagmus (HP:0000640)2.12288087
67Uterine neoplasm (HP:0010784)2.11785332
68Dysmetric saccades (HP:0000641)2.11075984
69Impulsivity (HP:0100710)2.10201356
70Small intestinal stenosis (HP:0012848)2.09461780
71Duodenal stenosis (HP:0100867)2.09461780
72Pancreatic cysts (HP:0001737)2.06208229
73Sandal gap (HP:0001852)2.06162900
74Clubbing of toes (HP:0100760)2.05949103
75Cystic hygroma (HP:0000476)2.05544595
76Abnormal biliary tract morphology (HP:0012440)2.05429383
77Syringomyelia (HP:0003396)2.05084047
78Spinal cord lesions (HP:0100561)2.05084047
79Neoplasm of the oral cavity (HP:0100649)2.05006721
80Abnormal pancreas size (HP:0012094)2.04658458
81Cafe-au-lait spot (HP:0000957)2.01701006
82Supernumerary spleens (HP:0009799)2.01674769
83Papillary thyroid carcinoma (HP:0002895)1.99968425
84Abnormality of DNA repair (HP:0003254)1.99294961
85Chronic hepatic failure (HP:0100626)1.96602356
86Abnormal lung lobation (HP:0002101)1.95282388
87Acanthocytosis (HP:0001927)1.94800612
88Abnormality of T cell number (HP:0011839)1.94779479
89Alveolar cell carcinoma (HP:0006519)1.93795873
90Myelodysplasia (HP:0002863)1.93604365
91Neoplasm of the colon (HP:0100273)1.93493346
92Abnormality of the renal collecting system (HP:0004742)1.93384335
93Abnormality of the duodenum (HP:0002246)1.93131091
94Abnormality of chromosome segregation (HP:0002916)1.92732606
95Macroorchidism (HP:0000053)1.92509100
96Aplasia/Hypoplasia of the tibia (HP:0005772)1.92385011
97Abnormality of the nasal septum (HP:0000419)1.92143195
98Obsessive-compulsive behavior (HP:0000722)1.91523370
99Bone marrow hypocellularity (HP:0005528)1.91512575
100Abnormality of the fovea (HP:0000493)1.90496674
101Protruding tongue (HP:0010808)1.88611013
102Stomach cancer (HP:0012126)1.88048867
1032-3 toe syndactyly (HP:0004691)1.87604005
104Flat capital femoral epiphysis (HP:0003370)1.86255433
105Aplasia/Hypoplasia of the sternum (HP:0006714)1.85792807
106Sloping forehead (HP:0000340)1.84052602
107Increased nuchal translucency (HP:0010880)1.83975155
108Pancreatic islet-cell hyperplasia (HP:0004510)1.83459080
109Long eyelashes (HP:0000527)1.83433323
110Abnormality of the columella (HP:0009929)1.83266607
111Abnormality of the labia minora (HP:0012880)1.83169552
112Duplicated collecting system (HP:0000081)1.81266543
113Homocystinuria (HP:0002156)1.80910688
114Abnormality of homocysteine metabolism (HP:0010919)1.80910688
115Sparse lateral eyebrow (HP:0005338)1.80333554
116Neoplasm of the tracheobronchial system (HP:0100552)1.78776394
117Abnormality of the incisor (HP:0000676)1.77473760
118Fair hair (HP:0002286)1.77135170
119Capillary hemangiomas (HP:0005306)1.76173869
120Short tibia (HP:0005736)1.75898098
121Truncal obesity (HP:0001956)1.74605597
122Neoplasm of the rectum (HP:0100743)1.73482863
123Neuroectodermal neoplasm (HP:0030061)1.72318318
124Neuroepithelial neoplasm (HP:0030063)1.72318318
125Nervous tissue neoplasm (HP:0030060)1.72318318
126White forelock (HP:0002211)1.72101429
127Oligodactyly (hands) (HP:0001180)1.71842420
128Thickened helices (HP:0000391)1.70854058
129Neuroblastic tumors (HP:0004376)1.70459014
130Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.70459014
131Neuroblastoma (HP:0003006)1.70459014
132Primitive neuroectodermal tumor (HP:0030065)1.70459014
133Subaortic stenosis (HP:0001682)1.70445563
134Abnormality of the left ventricular outflow tract (HP:0011103)1.70445563
135Preaxial hand polydactyly (HP:0001177)1.70312119
136Wide nose (HP:0000445)1.69792812
137Prominent nose (HP:0000448)1.69223562
138Abnormality of the prostate (HP:0008775)1.69187475
139Ovarian neoplasm (HP:0100615)1.68802113
140Urethral obstruction (HP:0000796)1.67993550
141Basal cell carcinoma (HP:0002671)1.67615159
142Patchy hypopigmentation of hair (HP:0011365)1.67021959
143Medial flaring of the eyebrow (HP:0010747)1.66814667
144Abnormal delayed hypersensitivity skin test (HP:0002963)1.64612106
145Renal hypoplasia (HP:0000089)1.64501868
146Abnormality of male internal genitalia (HP:0000022)1.62229158
147Oligohydramnios (HP:0001562)1.62171292
148Adrenal hypoplasia (HP:0000835)1.60777489
149Postaxial foot polydactyly (HP:0001830)1.60777426
150IgM deficiency (HP:0002850)1.60759820
151Hypoplastic iliac wings (HP:0002866)1.60500735
152Cupped ear (HP:0000378)1.60234246
153Patellar aplasia (HP:0006443)1.59978533
154Petechiae (HP:0000967)1.59866556
155Encephalitis (HP:0002383)1.58633645
156Nephrogenic diabetes insipidus (HP:0009806)1.58222420
157Generalized hypopigmentation of hair (HP:0011358)1.56937849
158Deep philtrum (HP:0002002)1.56848766
159Agammaglobulinemia (HP:0004432)1.54403439
160Lip pit (HP:0100267)1.53334199
161Convex nasal ridge (HP:0000444)1.52981361
16211 pairs of ribs (HP:0000878)1.51302242
163Chronic diarrhea (HP:0002028)1.51207054
164Absent frontal sinuses (HP:0002688)1.50999435
165Abnormality of the lacrimal duct (HP:0011481)1.50466767
166Abnormality of the nasolacrimal system (HP:0000614)1.50090079
167Abnormal spermatogenesis (HP:0008669)1.48908631
168Tetany (HP:0001281)1.48122405
169Renal cortical cysts (HP:0000803)1.48063474
170Optic nerve hypoplasia (HP:0000609)1.47703198
171Lymphoma (HP:0002665)1.47664990
172Embryonal neoplasm (HP:0002898)1.47547373
173Poor coordination (HP:0002370)1.47509574
174Tubulointerstitial nephritis (HP:0001970)1.47423478
175Aplasia/Hypoplasia of the patella (HP:0006498)1.47143002
176Thyroiditis (HP:0100646)1.47076732

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE15.74039835
2AKT34.09552448
3CASK3.33704233
4ZAK2.80194887
5TEC2.56968466
6MKNK22.37074168
7NUAK12.34603678
8SGK22.07666171
9MKNK12.05839370
10MAP3K102.02918014
11YES11.98175129
12TXK1.95762082
13FRK1.92595371
14TSSK61.86224030
15SIK31.85160725
16FGFR21.82930201
17INSRR1.82827925
18CDC71.75267540
19SRPK11.73772719
20CDK61.72356053
21STK161.71246915
22TTK1.70200574
23BRD41.63325733
24BMPR1B1.60877901
25GRK11.58754805
26NEK61.57333705
27PLK41.52412162
28IRAK31.51912324
29IRAK41.43031374
30FGFR11.42768484
31VRK11.41135814
32EIF2AK21.40373371
33MAP3K141.40116631
34MAP2K71.38235625
35WNK11.35319035
36WEE11.30024316
37PRPF4B1.28985878
38ERBB31.26123810
39PLK31.24977282
40BMPR21.24856044
41PNCK1.23492315
42DMPK1.20396373
43STK241.15914529
44EIF2AK31.15631744
45SGK4941.15344988
46SGK2231.15344988
47TNIK1.14981832
48ACVR1B1.13635819
49CDK81.12790314
50MAPK131.11811362
51SGK31.11236459
52CCNB11.05911139
53STK38L1.02903670
54CDK31.01427958
55ERBB40.97993762
56BRSK20.95684692
57CAMK1D0.91986742
58PLK20.91780132
59DYRK30.90065767
60ADRBK20.89085572
61MAP3K20.87942305
62RPS6KA40.87774287
63NLK0.87771273
64TRIM280.84229018
65CHUK0.82836069
66BCR0.82508569
67ATR0.81346298
68TAF10.81142474
69EEF2K0.76904977
70LATS10.76368784
71STK30.75604371
72IKBKB0.72068668
73FGFR40.70535063
74CAMK1G0.68996600
75CDK40.68874552
76BUB10.68766756
77RAF10.68642682
78PINK10.67930244
79ALK0.63794054
80MAP3K130.63201359
81JAK30.60860702
82TRPM70.59880835
83BRAF0.59702283
84CLK10.59076482
85MAPK70.57846438
86PRKCE0.57766539
87FLT30.57383132
88TNK20.56536172
89CHEK20.56086894
90PBK0.55149437
91NEK90.54239371
92PDK20.53933841
93MTOR0.53261382
94ATM0.52568842
95PIM10.51822439
96EIF2AK10.51786410
97CDK20.49101587
98CSNK1E0.48955597
99IKBKE0.48501419
100MUSK0.47877860
101STK100.47645706
102CAMKK20.47413966
103PLK10.47238779
104PDGFRB0.46910149
105MAP3K60.46864047
106PRKAA20.46804140
107MAPK100.46550592
108PASK0.45659572
109KSR10.44857639
110DYRK1A0.44689341
111MAP3K40.43947190
112BRSK10.42519469
113TGFBR10.42207797
114MAP3K70.41389639
115BLK0.41197473
116MARK30.40702419
117GRK70.40559555
118RPS6KB20.38890101
119PRKDC0.38380928
120STK40.38350163
121PIK3CG0.38289267
122CSNK1A1L0.38280335
123CDK120.38073709
124IRAK10.37875246
125CAMK40.36849087
126BTK0.36226708
127MAP3K120.36202466
128PRKCI0.35407411
129CHEK10.34789853
130IRAK20.34782475
131SGK10.34471867
132RPS6KB10.34315947
133NEK20.33185121
134MST40.32178957
135PIK3CA0.31353200
136FGFR30.30262812
137CDK10.29859012
138MELK0.29290438
139RPS6KA50.28783703
140ITK0.27863003
141AURKB0.27767590
142LYN0.25988398
143MAPK140.24801465

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034602.67123684
2Non-homologous end-joining_Homo sapiens_hsa034502.55035928
3Basal transcription factors_Homo sapiens_hsa030222.47774821
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.46888842
5Homologous recombination_Homo sapiens_hsa034402.28920830
6RNA polymerase_Homo sapiens_hsa030202.06093242
7Mismatch repair_Homo sapiens_hsa034302.05258121
8Thyroid cancer_Homo sapiens_hsa052162.04876769
9Lysine degradation_Homo sapiens_hsa003102.01015026
10RNA degradation_Homo sapiens_hsa030181.95861928
11DNA replication_Homo sapiens_hsa030301.80008814
12Base excision repair_Homo sapiens_hsa034101.77819447
13Cell cycle_Homo sapiens_hsa041101.76515396
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.70234090
15Primary immunodeficiency_Homo sapiens_hsa053401.63411245
16Endometrial cancer_Homo sapiens_hsa052131.61830537
17Nucleotide excision repair_Homo sapiens_hsa034201.61731383
18Non-small cell lung cancer_Homo sapiens_hsa052231.60750019
19Spliceosome_Homo sapiens_hsa030401.58582241
20NF-kappa B signaling pathway_Homo sapiens_hsa040641.56777328
21Chronic myeloid leukemia_Homo sapiens_hsa052201.55508966
22Rheumatoid arthritis_Homo sapiens_hsa053231.54202344
23Selenocompound metabolism_Homo sapiens_hsa004501.53818797
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.52113761
25Dorso-ventral axis formation_Homo sapiens_hsa043201.49875788
26Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.49562513
27Intestinal immune network for IgA production_Homo sapiens_hsa046721.47902418
28Allograft rejection_Homo sapiens_hsa053301.46522087
29Herpes simplex infection_Homo sapiens_hsa051681.40766268
30Regulation of autophagy_Homo sapiens_hsa041401.39814417
31Graft-versus-host disease_Homo sapiens_hsa053321.32676722
32Autoimmune thyroid disease_Homo sapiens_hsa053201.30896604
33Vitamin B6 metabolism_Homo sapiens_hsa007501.29009686
34RNA transport_Homo sapiens_hsa030131.28457556
35Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.24955212
36Renal cell carcinoma_Homo sapiens_hsa052111.24734513
37Measles_Homo sapiens_hsa051621.23696189
38Pancreatic cancer_Homo sapiens_hsa052121.23224934
39Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.23055200
40Acute myeloid leukemia_Homo sapiens_hsa052211.22990226
41Longevity regulating pathway - mammal_Homo sapiens_hsa042111.22760054
42mTOR signaling pathway_Homo sapiens_hsa041501.22221731
43Hematopoietic cell lineage_Homo sapiens_hsa046401.20918599
44Purine metabolism_Homo sapiens_hsa002301.20301203
45Choline metabolism in cancer_Homo sapiens_hsa052311.16704206
46Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.16477807
47Circadian rhythm_Homo sapiens_hsa047101.12774565
48Transcriptional misregulation in cancer_Homo sapiens_hsa052021.11260709
49Protein export_Homo sapiens_hsa030601.10982734
50Phototransduction_Homo sapiens_hsa047441.09992774
51Pyrimidine metabolism_Homo sapiens_hsa002401.06940011
52Sphingolipid metabolism_Homo sapiens_hsa006001.06116734
53Glioma_Homo sapiens_hsa052141.05794299
54RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.03383560
55mRNA surveillance pathway_Homo sapiens_hsa030151.03292295
56Type I diabetes mellitus_Homo sapiens_hsa049401.03002755
57Epstein-Barr virus infection_Homo sapiens_hsa051691.02401083
58SNARE interactions in vesicular transport_Homo sapiens_hsa041301.02172668
59Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.02098845
60B cell receptor signaling pathway_Homo sapiens_hsa046620.99870896
61Jak-STAT signaling pathway_Homo sapiens_hsa046300.99610810
62Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.98673786
63Taste transduction_Homo sapiens_hsa047420.96493311
64Thyroid hormone signaling pathway_Homo sapiens_hsa049190.95602592
65NOD-like receptor signaling pathway_Homo sapiens_hsa046210.95572802
66Maturity onset diabetes of the young_Homo sapiens_hsa049500.94358661
67ErbB signaling pathway_Homo sapiens_hsa040120.93119904
68p53 signaling pathway_Homo sapiens_hsa041150.93008220
69Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.92493905
70Antigen processing and presentation_Homo sapiens_hsa046120.90296006
71Oocyte meiosis_Homo sapiens_hsa041140.89675907
72Propanoate metabolism_Homo sapiens_hsa006400.89281605
73Glucagon signaling pathway_Homo sapiens_hsa049220.88150236
74Long-term potentiation_Homo sapiens_hsa047200.88059711
75Proteoglycans in cancer_Homo sapiens_hsa052050.87510433
76Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.84443982
77Influenza A_Homo sapiens_hsa051640.82109674
78Prolactin signaling pathway_Homo sapiens_hsa049170.81130841
79Small cell lung cancer_Homo sapiens_hsa052220.80476801
80Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.80099709
81Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.80006373
82Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.78474064
83AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.75482152
84Insulin signaling pathway_Homo sapiens_hsa049100.74823001
85Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.74741766
86Cysteine and methionine metabolism_Homo sapiens_hsa002700.72291240
87HTLV-I infection_Homo sapiens_hsa051660.71764411
88Morphine addiction_Homo sapiens_hsa050320.67307579
89HIF-1 signaling pathway_Homo sapiens_hsa040660.66420783
90Estrogen signaling pathway_Homo sapiens_hsa049150.65357471
91Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.63994861
92Prostate cancer_Homo sapiens_hsa052150.63802106
93Central carbon metabolism in cancer_Homo sapiens_hsa052300.63522119
94FoxO signaling pathway_Homo sapiens_hsa040680.62894949
95Hepatitis B_Homo sapiens_hsa051610.62798840
96Notch signaling pathway_Homo sapiens_hsa043300.61747719
97T cell receptor signaling pathway_Homo sapiens_hsa046600.61261973
98Insulin resistance_Homo sapiens_hsa049310.61211269
99Leishmaniasis_Homo sapiens_hsa051400.60377888
100Toll-like receptor signaling pathway_Homo sapiens_hsa046200.60239559
101Legionellosis_Homo sapiens_hsa051340.59672401
102Ovarian steroidogenesis_Homo sapiens_hsa049130.59406857
103Platelet activation_Homo sapiens_hsa046110.58704199
104Nicotine addiction_Homo sapiens_hsa050330.56374674
105Vitamin digestion and absorption_Homo sapiens_hsa049770.54880950
106Melanoma_Homo sapiens_hsa052180.54339949
107Hepatitis C_Homo sapiens_hsa051600.54088628
108Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.54084033
109MicroRNAs in cancer_Homo sapiens_hsa052060.53656103
110Tight junction_Homo sapiens_hsa045300.52320780
111Phosphatidylinositol signaling system_Homo sapiens_hsa040700.52023653
112Inositol phosphate metabolism_Homo sapiens_hsa005620.51381374
113TGF-beta signaling pathway_Homo sapiens_hsa043500.51306140
114Viral carcinogenesis_Homo sapiens_hsa052030.50824046
115Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.50602294
116Malaria_Homo sapiens_hsa051440.49551180
117TNF signaling pathway_Homo sapiens_hsa046680.48550814
118Colorectal cancer_Homo sapiens_hsa052100.48171536
119Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.48127742
120Arachidonic acid metabolism_Homo sapiens_hsa005900.47848404
121Long-term depression_Homo sapiens_hsa047300.47174547
122Serotonergic synapse_Homo sapiens_hsa047260.46996256
123Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.45084986
124Asthma_Homo sapiens_hsa053100.44509894
125Leukocyte transendothelial migration_Homo sapiens_hsa046700.44386897
126Phospholipase D signaling pathway_Homo sapiens_hsa040720.44046427
127Hippo signaling pathway_Homo sapiens_hsa043900.43999652
128PI3K-Akt signaling pathway_Homo sapiens_hsa041510.43606904
129Neurotrophin signaling pathway_Homo sapiens_hsa047220.43426615
130Adherens junction_Homo sapiens_hsa045200.42341687
131Wnt signaling pathway_Homo sapiens_hsa043100.42114488
132Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.40942127
133Chemokine signaling pathway_Homo sapiens_hsa040620.40901955
134Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.40764156
135Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.40731366
136Type II diabetes mellitus_Homo sapiens_hsa049300.40443053
137Toxoplasmosis_Homo sapiens_hsa051450.40169565
138Tuberculosis_Homo sapiens_hsa051520.39857424
139GnRH signaling pathway_Homo sapiens_hsa049120.38792457
140One carbon pool by folate_Homo sapiens_hsa006700.38692301
141Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.37900172
142Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.36921985
143Thyroid hormone synthesis_Homo sapiens_hsa049180.36208203
144Pathways in cancer_Homo sapiens_hsa052000.36010832
145Systemic lupus erythematosus_Homo sapiens_hsa053220.35973382
146Olfactory transduction_Homo sapiens_hsa047400.35958857
147Regulation of actin cytoskeleton_Homo sapiens_hsa048100.35821322
148cGMP-PKG signaling pathway_Homo sapiens_hsa040220.35658039
149MAPK signaling pathway_Homo sapiens_hsa040100.34164534
150ABC transporters_Homo sapiens_hsa020100.32031697
151Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.31844399
152Basal cell carcinoma_Homo sapiens_hsa052170.30752442
153AMPK signaling pathway_Homo sapiens_hsa041520.30453522

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