MZB1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous antigen (GO:0019883)8.21830940
2B cell receptor signaling pathway (GO:0050853)7.92932106
3complement activation, classical pathway (GO:0006958)7.55498382
4antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.98770831
5antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.98770831
6cytidine deamination (GO:0009972)5.76814082
7cytidine metabolic process (GO:0046087)5.76814082
8cytidine catabolic process (GO:0006216)5.76814082
9complement activation (GO:0006956)5.70024035
10positive regulation of B cell differentiation (GO:0045579)5.68317165
11negative regulation of B cell proliferation (GO:0030889)5.50632396
12regulation of B cell receptor signaling pathway (GO:0050855)5.48458211
13regulation of B cell differentiation (GO:0045577)5.17553313
14regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.81491162
15positive regulation of gamma-delta T cell activation (GO:0046645)4.80060420
16Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096)4.68795687
17immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:00024.68795687
18Fc-gamma receptor signaling pathway (GO:0038094)4.68795687
19B cell proliferation (GO:0042100)4.67224808
20Fc receptor mediated stimulatory signaling pathway (GO:0002431)4.61145619
21signal peptide processing (GO:0006465)4.52091754
22antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.50392092
23pyrimidine ribonucleoside catabolic process (GO:0046133)4.46540250
24somatic diversification of immune receptors via somatic mutation (GO:0002566)4.37327679
25somatic hypermutation of immunoglobulin genes (GO:0016446)4.37327679
26regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022354.36946028
27humoral immune response (GO:0006959)4.31147219
28mature B cell differentiation (GO:0002335)4.23703996
29B cell mediated immunity (GO:0019724)4.16838160
30Peyers patch development (GO:0048541)4.15125723
31mucosal-associated lymphoid tissue development (GO:0048537)4.15125723
32regulation of B cell apoptotic process (GO:0002902)4.10244994
33cellular response to zinc ion (GO:0071294)4.04349837
34immune response-activating cell surface receptor signaling pathway (GO:0002429)4.03357621
35T cell migration (GO:0072678)3.98547702
36positive regulation of respiratory burst (GO:0060267)3.96815735
37viral transcription (GO:0019083)3.94326875
38regulation of antigen processing and presentation (GO:0002577)3.93432977
39positive regulation of antigen processing and presentation (GO:0002579)3.90463427
40* regulation of B cell proliferation (GO:0030888)3.89445747
41negative T cell selection (GO:0043383)3.88998574
42ribosomal small subunit assembly (GO:0000028)3.86377254
43negative regulation of B cell apoptotic process (GO:0002903)3.84747879
44SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.83853546
45positive regulation of Rap GTPase activity (GO:0032854)3.79604402
46regulation of dendritic cell antigen processing and presentation (GO:0002604)3.78757903
47positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.77637613
48cotranslational protein targeting to membrane (GO:0006613)3.74809820
49protein targeting to ER (GO:0045047)3.74808652
50translational termination (GO:0006415)3.66594072
51negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.65622498
52interferon-gamma-mediated signaling pathway (GO:0060333)3.65495392
53antigen receptor-mediated signaling pathway (GO:0050851)3.63962862
54B cell homeostasis (GO:0001782)3.61537023
55mature B cell differentiation involved in immune response (GO:0002313)3.60982693
56regulation of gamma-delta T cell differentiation (GO:0045586)3.60955732
57response to type I interferon (GO:0034340)3.59490415
58establishment of protein localization to endoplasmic reticulum (GO:0072599)3.57938721
59cellular response to type I interferon (GO:0071357)3.57342263
60type I interferon signaling pathway (GO:0060337)3.57342263
61protein localization to endoplasmic reticulum (GO:0070972)3.51693512
62regulation of interferon-beta biosynthetic process (GO:0045357)3.50819777
63protein activation cascade (GO:0072376)3.50696616
64B cell activation (GO:0042113)3.49601559
65antimicrobial humoral response (GO:0019730)3.48641992
66regulation of respiratory burst (GO:0060263)3.48110694
67respiratory burst (GO:0045730)3.44961111
68DNA deamination (GO:0045006)3.44535876
69positive regulation of granulocyte differentiation (GO:0030854)3.40475355
70antibacterial humoral response (GO:0019731)3.39668732
71positive T cell selection (GO:0043368)3.39524445
72regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.36387256
73regulation of germinal center formation (GO:0002634)3.36030735
74ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)3.30307172
75thymic T cell selection (GO:0045061)3.29107397
76lymphocyte homeostasis (GO:0002260)3.27878534
77regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.27695187
78translational elongation (GO:0006414)3.27422248
79response to interferon-beta (GO:0035456)3.27342712
80positive regulation of gene expression, epigenetic (GO:0045815)3.25269772
81positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.24483617
82regulation of gamma-delta T cell activation (GO:0046643)3.22143470
83negative regulation of gene silencing (GO:0060969)3.20353538
84defense response to protozoan (GO:0042832)3.18328944
85immunoglobulin mediated immune response (GO:0016064)3.16543328
86detection of bacterium (GO:0016045)3.14785833
87regulation of Rap GTPase activity (GO:0032317)3.11055481
88negative regulation of phagocytosis (GO:0050765)3.10740641
89regulation of alpha-beta T cell proliferation (GO:0046640)3.10192082
90ribosomal small subunit biogenesis (GO:0042274)3.09842755
91serine transport (GO:0032329)3.06021667
92positive regulation of B cell activation (GO:0050871)3.04776378
93NIK/NF-kappaB signaling (GO:0038061)3.04674936
94negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.03107705
95mast cell activation (GO:0045576)3.02320615
96natural killer cell mediated immunity (GO:0002228)3.02052930
97natural killer cell mediated cytotoxicity (GO:0042267)3.02052930
98T cell selection (GO:0045058)3.01122497
99negative regulation of thymocyte apoptotic process (GO:0070244)3.00757276
100negative regulation of histone methylation (GO:0031061)3.00547180
101nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.00335277
102CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.99933042
103regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664)2.99206367
104positive thymic T cell selection (GO:0045059)2.97639156
105germinal center formation (GO:0002467)2.95007556
106positive regulation of protein homooligomerization (GO:0032464)2.94668671
107purine deoxyribonucleotide catabolic process (GO:0009155)2.94590100
108T cell costimulation (GO:0031295)2.94546756
109B cell differentiation (GO:0030183)2.94250824
110* regulation of B cell activation (GO:0050864)2.94046503
111immune response-activating signal transduction (GO:0002757)2.93742239
112somatic diversification of immunoglobulins (GO:0016445)2.93699350
113telomere maintenance via semi-conservative replication (GO:0032201)2.93660596
114response to protozoan (GO:0001562)2.93139001
115positive regulation of alpha-beta T cell proliferation (GO:0046641)2.92394726
116leukocyte homeostasis (GO:0001776)2.92383723
117lymphocyte costimulation (GO:0031294)2.91947553
118chaperone mediated protein folding requiring cofactor (GO:0051085)2.91824886
119positive regulation of B cell proliferation (GO:0030890)2.91546986
120cellular response to interferon-gamma (GO:0071346)2.90979086
121regulation of interleukin-12 biosynthetic process (GO:0045075)2.89852972
122positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.86735747
123T cell homeostasis (GO:0043029)2.86198131
124cellular response to interferon-beta (GO:0035458)2.84664356
125natural killer cell differentiation (GO:0001779)2.84589978
126mononuclear cell proliferation (GO:0032943)2.84137994
127B cell activation involved in immune response (GO:0002312)2.83485103
128lymphocyte proliferation (GO:0046651)2.83285700
129V(D)J recombination (GO:0033151)2.82665318
130negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.81700542
131somatic diversification of immune receptors (GO:0002200)2.81436602
132viral life cycle (GO:0019058)2.80998198
133cellular protein complex disassembly (GO:0043624)2.80604135
134glomerular filtration (GO:0003094)2.80598199
135DNA strand elongation involved in DNA replication (GO:0006271)2.80539850
136detection of other organism (GO:0098543)2.79937301
137regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)2.79127381
138regulation of nuclease activity (GO:0032069)2.75881898
139GDP-mannose metabolic process (GO:0019673)2.75795413
140negative thymic T cell selection (GO:0045060)2.75688532
141L-serine transport (GO:0015825)2.75526770
142positive regulation of nuclease activity (GO:0032075)2.75121530
143negative regulation of bone resorption (GO:0045779)2.74005357
144regulation of cellular extravasation (GO:0002691)2.70851342
145response to interferon-gamma (GO:0034341)2.68138415
146myeloid dendritic cell activation (GO:0001773)2.67783834
147T cell lineage commitment (GO:0002360)2.67176423
148regulation of thymocyte apoptotic process (GO:0070243)2.65998967
149deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.65712314
150negative regulation of leukocyte apoptotic process (GO:2000107)2.65478498
151response to interleukin-15 (GO:0070672)2.57152916
152Arp2/3 complex-mediated actin nucleation (GO:0034314)2.56801151
153regulation of granulocyte differentiation (GO:0030852)2.55732647
154negative regulation of cell killing (GO:0031342)2.55729080
155negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.55729080
156positive regulation of defense response to virus by host (GO:0002230)2.55475496
157lymphocyte migration (GO:0072676)2.54390102
158positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.51701643

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.42572042
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.02393250
3MYC_22102868_ChIP-Seq_BL_Human4.72111942
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.11479660
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.84357152
6BP1_19119308_ChIP-ChIP_Hs578T_Human3.76915161
7SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.72988063
8IRF8_21731497_ChIP-ChIP_J774_Mouse3.23491651
9VDR_21846776_ChIP-Seq_THP-1_Human3.17673806
10FOXM1_23109430_ChIP-Seq_U2OS_Human3.04942104
11E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.91024371
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.82321772
13STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.79989917
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.71811576
15MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.62903392
16SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.58864068
17EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.50535326
18SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.34616016
19MAF_26560356_Chip-Seq_TH1_Human2.31844638
20MYB_26560356_Chip-Seq_TH2_Human2.25638872
21MYB_26560356_Chip-Seq_TH1_Human2.18205895
22IRF8_27001747_Chip-Seq_BMDM_Mouse2.13658004
23RUNX_20019798_ChIP-Seq_JUKART_Human2.12053819
24CIITA_25753668_ChIP-Seq_RAJI_Human2.08431670
25E2F4_17652178_ChIP-ChIP_JURKAT_Human2.05295052
26UTX_26944678_Chip-Seq_JUKART_Human2.05000326
27VDR_24763502_ChIP-Seq_THP-1_Human1.97901343
28FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.95818299
29SPI1_23547873_ChIP-Seq_NB4_Human1.84080090
30CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.83488031
31SCL_19346495_ChIP-Seq_HPC-7_Human1.80630937
32STAT4_19710469_ChIP-ChIP_TH1__Mouse1.76968242
33NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.75726439
34NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.73861222
35ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.73809245
36FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.67156747
37KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.66557666
38FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.66383188
39TCF7_22412390_ChIP-Seq_EML_Mouse1.64609230
40ELF1_17652178_ChIP-ChIP_JURKAT_Human1.63630566
41LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.62879996
42NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.59878615
43IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.58904962
44NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.57772142
45TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.55657460
46BRD4_27068464_Chip-Seq_AML-cells_Mouse1.54036212
47MAF_26560356_Chip-Seq_TH2_Human1.52316928
48VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.51343689
49SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.51094735
50BCL6_27268052_Chip-Seq_Bcells_Human1.50674414
51FOXP3_21729870_ChIP-Seq_TREG_Human1.49049998
52TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.48533844
53STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.47223819
54SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.46278762
55MYC_19079543_ChIP-ChIP_MESCs_Mouse1.43787340
56RUNX1_22412390_ChIP-Seq_EML_Mouse1.43369979
57VDR_23849224_ChIP-Seq_CD4+_Human1.39473007
58KDM5A_27292631_Chip-Seq_BREAST_Human1.38380562
59RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.38103932
60KDM2B_26808549_Chip-Seq_DND41_Human1.37564360
61GATA2_22383799_ChIP-Seq_G1ME_Mouse1.35987424
62PU.1_20513432_ChIP-Seq_Bcells_Mouse1.35151668
63MYC_18555785_ChIP-Seq_MESCs_Mouse1.33237318
64KDM2B_26808549_Chip-Seq_SUP-B15_Human1.32292775
65VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.32070103
66BCOR_27268052_Chip-Seq_Bcells_Human1.29235966
67GATA1_22383799_ChIP-Seq_G1ME_Mouse1.28156957
68EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.26801430
69ERG_20887958_ChIP-Seq_HPC-7_Mouse1.26306216
70GATA3_27048872_Chip-Seq_THYMUS_Human1.24840378
71SPI1_23127762_ChIP-Seq_K562_Human1.24251552
72HOXB4_20404135_ChIP-ChIP_EML_Mouse1.23179675
73EST1_17652178_ChIP-ChIP_JURKAT_Human1.22624978
74GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.21155197
75MYB_21317192_ChIP-Seq_ERMYB_Mouse1.20504067
76XRN2_22483619_ChIP-Seq_HELA_Human1.19963557
77MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.18585321
78CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.17417880
79ETS1_20019798_ChIP-Seq_JURKAT_Human1.17234845
80CREB1_15753290_ChIP-ChIP_HEK293T_Human1.16671024
81E2F1_21310950_ChIP-Seq_MCF-7_Human1.16269255
82MYC_19030024_ChIP-ChIP_MESCs_Mouse1.14866626
83ELK3_25401928_ChIP-Seq_HUVEC_Human1.13727016
84KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.13632648
85RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.11073336
86RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.08275150
87MYC_18358816_ChIP-ChIP_MESCs_Mouse1.07397414
88NOTCH1_21737748_ChIP-Seq_TLL_Human1.07225006
89EGR1_23403033_ChIP-Seq_LIVER_Mouse1.06782508
90GABP_17652178_ChIP-ChIP_JURKAT_Human1.04905235
91KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.04102778
92STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.03294148
93GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.02762084
94PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.02245803
95E2F1_20622854_ChIP-Seq_HELA_Human1.01901052
96TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.97853075
97P68_20966046_ChIP-Seq_HELA_Human0.97387293
98CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.96870642
99SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96391907
100CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.96390712
101RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.93010583
102LXR_22292898_ChIP-Seq_THP-1_Human0.92677695
103YY1_21170310_ChIP-Seq_MESCs_Mouse0.91600715
104GATA3_26560356_Chip-Seq_TH2_Human0.91467323
105PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.91376182
106CTCF_21964334_ChIP-Seq_BJAB-B_Human0.91105434
107NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.90929436
108SRF_21415370_ChIP-Seq_HL-1_Mouse0.90798675
109GATA1_22025678_ChIP-Seq_K562_Human0.89471692
110PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.88818527
111YY1_22570637_ChIP-Seq_MALME-3M_Human0.88541292
112DCP1A_22483619_ChIP-Seq_HELA_Human0.87938492
113P300_27268052_Chip-Seq_Bcells_Human0.87877135
114LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.86974832
115JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.86510205
116SPI1_20517297_ChIP-Seq_HL60_Human0.86026414
117STAT1_20625510_ChIP-Seq_HELA_Human0.85820870
118IRF1_19129219_ChIP-ChIP_H3396_Human0.85428558
119ELK1_19687146_ChIP-ChIP_HELA_Human0.84084429
120FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83872793
121GABP_19822575_ChIP-Seq_HepG2_Human0.81641242
122CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.81340284
123NCOR1_26117541_ChIP-Seq_K562_Human0.80882092
124CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.80048097
125ELF1_20517297_ChIP-Seq_JURKAT_Human0.79401832
126MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.78002866

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation5.77605828
2MP0001800_abnormal_humoral_immune4.92408281
3MP0001790_abnormal_immune_system4.47628569
4MP0005387_immune_system_phenotype4.47628569
5MP0002452_abnormal_antigen_presenting3.71153417
6MP0003303_peritoneal_inflammation3.60462080
7MP0000685_abnormal_immune_system3.41841904
8MP0005671_abnormal_response_to3.33524239
9MP0002723_abnormal_immune_serum3.12417981
10MP0002420_abnormal_adaptive_immunity3.04646186
11MP0002398_abnormal_bone_marrow3.04295333
12MP0001819_abnormal_immune_cell2.97404398
13MP0005000_abnormal_immune_tolerance2.94213911
14MP0000716_abnormal_immune_system2.73406183
15MP0000689_abnormal_spleen_morphology2.73107489
16MP0002429_abnormal_blood_cell2.31149999
17MP0002722_abnormal_immune_system2.30802319
18MP0010234_abnormal_vibrissa_follicle2.30313489
19MP0005025_abnormal_response_to2.28427295
20MP0003763_abnormal_thymus_physiology2.27830701
21MP0003693_abnormal_embryo_hatching2.04797964
22MP0003724_increased_susceptibility_to2.03981081
23MP0009785_altered_susceptibility_to2.03833814
24MP0003300_gastrointestinal_ulcer2.03359733
25MP0001879_abnormal_lymphatic_vessel1.98535645
26MP0002148_abnormal_hypersensitivity_rea1.95182401
27MP0003436_decreased_susceptibility_to1.92703723
28MP0002166_altered_tumor_susceptibility1.89376979
29MP0010094_abnormal_chromosome_stability1.85700511
30MP0002396_abnormal_hematopoietic_system1.81532923
31MP0000703_abnormal_thymus_morphology1.77585729
32MP0010155_abnormal_intestine_physiology1.77034520
33MP0002419_abnormal_innate_immunity1.74113441
34MP0009333_abnormal_splenocyte_physiolog1.68357112
35MP0001845_abnormal_inflammatory_respons1.67346624
36MP0005645_abnormal_hypothalamus_physiol1.61656909
37MP0004947_skin_inflammation1.60989818
38MP0002405_respiratory_system_inflammati1.56831292
39MP0004808_abnormal_hematopoietic_stem1.49118733
40MP0006054_spinal_hemorrhage1.48608279
41MP0003077_abnormal_cell_cycle1.48381942
42MP0002019_abnormal_tumor_incidence1.48240113
43MP0008057_abnormal_DNA_replication1.47327570
44MP0001853_heart_inflammation1.41493805
45MP0002933_joint_inflammation1.39563436
46MP0001873_stomach_inflammation1.36345914
47MP0000490_abnormal_crypts_of1.35972500
48MP0004264_abnormal_extraembryonic_tissu1.33169314
49MP0002006_tumorigenesis1.29296324
50MP0003866_abnormal_defecation1.27319476
51MP0005310_abnormal_salivary_gland1.23747628
52MP0005464_abnormal_platelet_physiology1.22826278
53MP0005220_abnormal_exocrine_pancreas1.19466593
54MP0004957_abnormal_blastocyst_morpholog1.16874787
55MP0003806_abnormal_nucleotide_metabolis1.16560308
56MP0009764_decreased_sensitivity_to1.11684239
57MP0003252_abnormal_bile_duct1.09945495
58MP0003111_abnormal_nucleus_morphology1.07953919
59MP0000372_irregular_coat_pigmentation1.06698064
60MP0005076_abnormal_cell_differentiation1.03982761
61MP0004510_myositis1.03493705
62MP0002876_abnormal_thyroid_physiology1.01317926
63MP0004043_abnormal_pH_regulation0.99150128
64MP0002653_abnormal_ependyma_morphology0.91669768
65MP0002139_abnormal_hepatobiliary_system0.90633508
66MP0002136_abnormal_kidney_physiology0.89648132
67MP0004381_abnormal_hair_follicle0.88796920
68MP0002132_abnormal_respiratory_system0.88083843
69MP0005397_hematopoietic_system_phenotyp0.87722128
70MP0001545_abnormal_hematopoietic_system0.87722128
71MP0000465_gastrointestinal_hemorrhage0.87622499
72MP0009278_abnormal_bone_marrow0.86810953
73MP0008872_abnormal_physiological_respon0.86503547
74MP0000350_abnormal_cell_proliferation0.84892043
75MP0010352_gastrointestinal_tract_polyps0.84794522
76MP0001986_abnormal_taste_sensitivity0.84778177
77MP0008469_abnormal_protein_level0.81153278
78MP0006082_CNS_inflammation0.79298558
79MP0009643_abnormal_urine_homeostasis0.78741388
80MP0005166_decreased_susceptibility_to0.78190299
81MP0001730_embryonic_growth_arrest0.78132306
82MP0001764_abnormal_homeostasis0.75887866
83MP0000313_abnormal_cell_death0.75226252
84MP0009840_abnormal_foam_cell0.75107001
85MP0000003_abnormal_adipose_tissue0.73807402
86MP0003183_abnormal_peptide_metabolism0.73189079
87MP0002009_preneoplasia0.72336146
88MP0003943_abnormal_hepatobiliary_system0.70954162
89MP0001919_abnormal_reproductive_system0.69127571
90MP0001191_abnormal_skin_condition0.68926487
91MP0001663_abnormal_digestive_system0.68251791
92MP0005584_abnormal_enzyme/coenzyme_acti0.68164503
93MP0006036_abnormal_mitochondrial_physio0.67856581
94MP0002693_abnormal_pancreas_physiology0.66024265
95MP0001533_abnormal_skeleton_physiology0.65997275
96MP0005360_urolithiasis0.65208301
97MP0008877_abnormal_DNA_methylation0.65048019
98MP0010307_abnormal_tumor_latency0.65000862
99MP0002083_premature_death0.64686860
100MP0002095_abnormal_skin_pigmentation0.64592004
101MP0000477_abnormal_intestine_morphology0.64397001
102MP0005174_abnormal_tail_pigmentation0.63942217
103MP0000013_abnormal_adipose_tissue0.63826217
104MP0001666_abnormal_nutrient_absorption0.62674681
105MP0005621_abnormal_cell_physiology0.61423773
106MP0002163_abnormal_gland_morphology0.61385406
107MP0008058_abnormal_DNA_repair0.60889652
108MP0003075_altered_response_to0.60604136
109MP0009763_increased_sensitivity_to0.60362206
110MP0009931_abnormal_skin_appearance0.60023563
111MP0003045_fibrosis0.59796684
112MP0005381_digestive/alimentary_phenotyp0.57834593
113MP0008007_abnormal_cellular_replicative0.57182517
114MP0000681_abnormal_thyroid_gland0.54260098
115MP0001348_abnormal_lacrimal_gland0.53455421
116MP0001944_abnormal_pancreas_morphology0.53294771
117MP0000609_abnormal_liver_physiology0.52049811
118MP0000015_abnormal_ear_pigmentation0.51453419
119MP0002138_abnormal_hepatobiliary_system0.49913578
120MP0003091_abnormal_cell_migration0.49562642
121MP0000858_altered_metastatic_potential0.48902979
122MP0005451_abnormal_body_composition0.47885492
123MP0005075_abnormal_melanosome_morpholog0.46229210
124MP0002928_abnormal_bile_duct0.45994372
125MP0005023_abnormal_wound_healing0.44256629
126MP0002168_other_aberrant_phenotype0.44125945
127MP0003646_muscle_fatigue0.43311856
128MP0001697_abnormal_embryo_size0.43216866
129MP0002080_prenatal_lethality0.42555424
130MP0000598_abnormal_liver_morphology0.42326185

Predicted human phenotypes

RankGene SetZ-score
1Cellulitis (HP:0100658)7.93763630
2B lymphocytopenia (HP:0010976)7.21359345
3Abnormality of B cell number (HP:0010975)7.21359345
4Recurrent bronchitis (HP:0002837)7.14023188
5Verrucae (HP:0200043)6.84124860
6Papilloma (HP:0012740)6.84124860
7Colitis (HP:0002583)6.61662147
8Recurrent sinusitis (HP:0011108)6.57570482
9Gastrointestinal stroma tumor (HP:0100723)5.80731381
10Recurrent viral infections (HP:0004429)5.48769329
11IgM deficiency (HP:0002850)5.42716094
12Meningitis (HP:0001287)5.42035479
13Inflammation of the large intestine (HP:0002037)5.38905235
14Recurrent pneumonia (HP:0006532)5.32747271
15Gastrointestinal inflammation (HP:0004386)5.27125901
16Chronic sinusitis (HP:0011109)4.98286641
17Osteomyelitis (HP:0002754)4.86543073
18Recurrent lower respiratory tract infections (HP:0002783)4.78628419
19Chronic otitis media (HP:0000389)4.44855869
20Bronchitis (HP:0012387)4.16659005
21Sepsis (HP:0100806)4.03887903
22Recurrent otitis media (HP:0000403)3.98434258
23Panhypogammaglobulinemia (HP:0003139)3.91687190
24Thyroiditis (HP:0100646)3.72681700
25IgA deficiency (HP:0002720)3.72090544
26Emphysema (HP:0002097)3.71095203
27Lymphopenia (HP:0001888)3.63454379
28Skin rash (HP:0000988)3.60762231
29Autoimmune hemolytic anemia (HP:0001890)3.55232420
30Abnormality of cells of the lymphoid lineage (HP:0012140)3.55052090
31IgG deficiency (HP:0004315)3.33724230
32Abnormality of the prostate (HP:0008775)3.33472448
33Abnormal delayed hypersensitivity skin test (HP:0002963)3.30359772
34Small epiphyses (HP:0010585)3.23887103
35Abnormality of T cell physiology (HP:0011840)3.23104845
36Interstitial pulmonary disease (HP:0006530)3.10439108
37Vasculitis (HP:0002633)3.01452578
38Basal cell carcinoma (HP:0002671)2.90307806
39Recurrent abscess formation (HP:0002722)2.84116996
40Abnormality of T cells (HP:0002843)2.82053768
41Recurrent fungal infections (HP:0002841)2.81524837
42Restrictive lung disease (HP:0002091)2.77945396
43Prostate neoplasm (HP:0100787)2.69410334
44Recurrent bacterial skin infections (HP:0005406)2.68421829
45Thrombocytosis (HP:0001894)2.55016951
46Neutropenia (HP:0001875)2.51948320
47Increased IgM level (HP:0003496)2.50596253
48Onycholysis (HP:0001806)2.50388039
49Nasal polyposis (HP:0100582)2.45818699
50Skin ulcer (HP:0200042)2.43408839
51Squamous cell carcinoma (HP:0002860)2.42304141
52Decreased circulating renin level (HP:0003351)2.41203836
53Leukocytosis (HP:0001974)2.37117684
54Lymphoma (HP:0002665)2.37007502
55Autoimmune thrombocytopenia (HP:0001973)2.34766220
56Abnormality of eosinophils (HP:0001879)2.33603636
57Leukopenia (HP:0001882)2.31455987
58Mitral stenosis (HP:0001718)2.30966978
59Abnormality of T cell number (HP:0011839)2.28692869
60Erythema (HP:0010783)2.28438458
61Elevated erythrocyte sedimentation rate (HP:0003565)2.25877659
62Mediastinal lymphadenopathy (HP:0100721)2.25071560
63Dry hair (HP:0011359)2.24487924
64T lymphocytopenia (HP:0005403)2.23936881
65Flattened epiphyses (HP:0003071)2.23353122
66Dicarboxylic aciduria (HP:0003215)2.22521802
67Abnormality of dicarboxylic acid metabolism (HP:0010995)2.22521802
68Urticaria (HP:0001025)2.21198377
69Recurrent skin infections (HP:0001581)2.19243759
70Acute hepatic failure (HP:0006554)2.18170712
71Hypoplasia of the capital femoral epiphysis (HP:0003090)2.16472097
72Gastrointestinal infarctions (HP:0005244)2.16236403
73Chest pain (HP:0100749)2.15577217
74Dehydration (HP:0001944)2.14656440
75Acute lymphatic leukemia (HP:0006721)2.14039962
76Eczematoid dermatitis (HP:0000976)2.14014610
77Abnormality of the pleura (HP:0002103)2.13013548
78Abnormality of macrophages (HP:0004311)2.12660954
79Type I transferrin isoform profile (HP:0003642)2.11994115
80Abnormality of small intestinal villus morphology (HP:0011472)2.11383124
81Villous atrophy (HP:0011473)2.11383124
82Recurrent cutaneous fungal infections (HP:0011370)2.11041068
83Chronic mucocutaneous candidiasis (HP:0002728)2.11041068
84Bronchiectasis (HP:0002110)2.09822188
85Abnormality of male internal genitalia (HP:0000022)2.09350829
86Combined immunodeficiency (HP:0005387)2.08985110
87Abnormality of the nasal mucosa (HP:0000433)2.03540640
88Increased IgE level (HP:0003212)2.03175184
89Viral hepatitis (HP:0006562)2.02401710
90Agammaglobulinemia (HP:0004432)11.2992545
91Severe combined immunodeficiency (HP:0004430)1.97881685
92Chronic obstructive pulmonary disease (HP:0006510)1.96557243
93Obstructive lung disease (HP:0006536)1.96557243
94Abnormality of the fingertips (HP:0001211)1.95107945
95Vertebral arch anomaly (HP:0008438)1.90606203
96Pustule (HP:0200039)1.86410736
97Premature loss of primary teeth (HP:0006323)1.85775433
98Alkalosis (HP:0001948)1.85409272
99External ear malformation (HP:0008572)1.84830323
100Stomatitis (HP:0010280)1.84540804
101Cerebral palsy (HP:0100021)1.82892626
102Reduced antithrombin III activity (HP:0001976)1.81765138
103Hemoptysis (HP:0002105)1.78430618
104Irregular vertebral endplates (HP:0003301)1.78136128
105Teleangiectasia of the skin (HP:0100585)1.77017027
106Abnormal protein glycosylation (HP:0012346)1.76705686
107Abnormal glycosylation (HP:0012345)1.76705686
108Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.76705686
109Abnormal protein N-linked glycosylation (HP:0012347)1.76705686
110Encephalitis (HP:0002383)1.70240378
111Absent epiphyses (HP:0010577)1.70017006
112Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.70017006
113Recurrent gram-negative bacterial infections (HP:0005420)1.68839522
114Myositis (HP:0100614)1.62942134
115Eosinophilia (HP:0001880)1.62218557
116Abnormality of cells of the erythroid lineage (HP:0012130)1.58326050
117Hypoplasia of the thymus (HP:0000778)1.57839884
118Petechiae (HP:0000967)1.57636165
119Arthralgia (HP:0002829)1.55737599
120Reticulocytopenia (HP:0001896)1.55057420
121Conical tooth (HP:0000698)1.54874711
122Pulmonary infiltrates (HP:0002113)1.53764693
123Hypergammaglobulinemia (HP:0010702)1.52769199
124Blepharitis (HP:0000498)1.49438293
125Aplasia/Hypoplasia of the thymus (HP:0010515)1.48124928
126Granulocytopenia (HP:0001913)1.47710693
127Chronic diarrhea (HP:0002028)1.47600341
128Limb hypertonia (HP:0002509)1.42562095

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K16.07815761
2ERN15.74825687
3MAP3K104.38282712
4CSF1R3.11068683
5EEF2K2.98303804
6SYK2.85319316
7GRK62.79367443
8BLK2.38733362
9NME22.28458705
10RIPK42.23058379
11BTK2.07916047
12MAP3K132.07830170
13VRK21.99974177
14SIK21.98544065
15FRK1.95669629
16TYK21.93433750
17TBK11.93076790
18MAP3K141.77788782
19STK101.71313656
20ZAK1.66915046
21NEK21.58831013
22LYN1.57716362
23LRRK21.54256246
24EIF2AK31.53537140
25PRPF4B1.51632439
26SMG11.49035920
27TESK21.45714815
28VRK11.45224131
29CLK11.35437572
30KIT1.32958551
31KDR1.31899405
32PRKCH1.31328179
33TXK1.31240906
34IKBKE1.30768677
35NUAK11.25001223
36FES1.22332071
37IKBKB1.10850681
38HCK1.10284668
39IRAK41.09981229
40MAPKAPK31.02097179
41PIK3CG1.01086508
42CDC70.99085926
43MST40.97685737
44JAK10.96247165
45HIPK20.95097042
46IRAK30.90598921
47PIM10.90195029
48JAK30.89935720
49BMPR20.88862290
50TAOK30.88460469
51CDK40.87746898
52PRKCQ0.87500286
53TEC0.86208291
54ITK0.86102474
55LCK0.85031948
56BUB10.84557668
57MAPKAPK50.84202358
58RPS6KB20.83680914
59TRIB30.80927094
60PIM20.80811931
61STK40.80796447
62PKN20.80337352
63SIK30.80157983
64SIK10.78798301
65ACVR1B0.78750846
66RPS6KA50.75969333
67CCNB10.73624976
68DAPK10.73126793
69SCYL20.70691284
70MAPK110.70453471
71IRAK10.70384177
72PRKCI0.68241964
73MAP3K110.67310750
74CDK120.67109385
75ZAP700.65898617
76MAPK120.64596557
77BMPR1B0.63235926
78MAP3K90.63158959
79MAP2K20.62853134
80CSK0.62660498
81BCKDK0.61708349
82MAP3K80.61279292
83ADRBK20.61094880
84EIF2AK10.60228593
85ARAF0.59987833
86RPS6KA40.59848652
87TLK10.58090214
88ALK0.57520067
89MARK30.56556518
90TAF10.55659294
91JAK20.55384088
92PDK10.54941808
93CHUK0.54882496
94FLT30.54509480
95CDK190.49487232
96MATK0.46036188
97CDK80.45978807
98NLK0.45167205
99TNK20.44777158
100PRKD20.43365831
101TGFBR20.41762199
102MAPK40.41272681
103MAP3K70.41257172
104PASK0.40728448
105RAF10.40466355
106CDK70.37918231
107DAPK30.37336688
108CHEK10.37327144
109CAMKK10.37221018
110OXSR10.36267518
111ABL10.36233964
112FGFR30.36050232
113BRD40.34353624
114MELK0.34167494
115FGFR40.33742151
116MAP2K30.33682643
117ATR0.33594297
118CAMKK20.33401533
119MAP2K60.32985966
120MAPK70.32835580
121BRSK10.32021019
122CDK90.31978664
123MAPK30.31086739
124CHEK20.30666296
125INSRR0.30211683
126PRKCD0.28197019
127KSR20.28172410
128MAPKAPK20.27798109
129FGR0.27584400
130FYN0.27566422
131PRKD10.26581141
132AURKB0.26570351
133MAP4K20.26381443
134BRAF0.26159662
135INSR0.25673529
136GRK10.25387991

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053407.08375426
2B cell receptor signaling pathway_Homo sapiens_hsa046625.25830547
3Intestinal immune network for IgA production_Homo sapiens_hsa046724.40567278
4Graft-versus-host disease_Homo sapiens_hsa053323.89796241
5Type I diabetes mellitus_Homo sapiens_hsa049403.31819431
6Protein export_Homo sapiens_hsa030602.86227213
7Base excision repair_Homo sapiens_hsa034102.80789865
8DNA replication_Homo sapiens_hsa030302.76891746
9NF-kappa B signaling pathway_Homo sapiens_hsa040642.40840159
10Ribosome_Homo sapiens_hsa030102.39858292
11Staphylococcus aureus infection_Homo sapiens_hsa051502.39680161
12Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.27031102
13Antigen processing and presentation_Homo sapiens_hsa046122.26645136
14Mismatch repair_Homo sapiens_hsa034302.12481387
15Non-homologous end-joining_Homo sapiens_hsa034501.94807993
16Osteoclast differentiation_Homo sapiens_hsa043801.66633084
17Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.63838951
18Hematopoietic cell lineage_Homo sapiens_hsa046401.61362508
19N-Glycan biosynthesis_Homo sapiens_hsa005101.60148102
20Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.56013480
21Leishmaniasis_Homo sapiens_hsa051401.51565950
22Measles_Homo sapiens_hsa051621.28995125
23Herpes simplex infection_Homo sapiens_hsa051681.27285495
24T cell receptor signaling pathway_Homo sapiens_hsa046601.23318969
25Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.23131223
26Rheumatoid arthritis_Homo sapiens_hsa053231.22101542
27Spliceosome_Homo sapiens_hsa030401.10644223
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.07934263
29Epstein-Barr virus infection_Homo sapiens_hsa051691.07422592
30Hepatitis B_Homo sapiens_hsa051611.05659082
31RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.05552478
32Non-small cell lung cancer_Homo sapiens_hsa052231.04234463
33Homologous recombination_Homo sapiens_hsa034401.01738881
34Toll-like receptor signaling pathway_Homo sapiens_hsa046201.01067775
35Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.00321128
36Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.99065652
37Apoptosis_Homo sapiens_hsa042100.96773231
38Leukocyte transendothelial migration_Homo sapiens_hsa046700.95233687
39HTLV-I infection_Homo sapiens_hsa051660.93295970
40Tuberculosis_Homo sapiens_hsa051520.91279609
41Acute myeloid leukemia_Homo sapiens_hsa052210.91271617
42Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.91080642
43Nucleotide excision repair_Homo sapiens_hsa034200.88880385
44Shigellosis_Homo sapiens_hsa051310.88219431
45Chronic myeloid leukemia_Homo sapiens_hsa052200.87386190
46Chemokine signaling pathway_Homo sapiens_hsa040620.86811391
47Caffeine metabolism_Homo sapiens_hsa002320.85747973
48alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.85337320
49Viral myocarditis_Homo sapiens_hsa054160.82544010
50Alcoholism_Homo sapiens_hsa050340.81574821
51Asthma_Homo sapiens_hsa053100.81148715
52p53 signaling pathway_Homo sapiens_hsa041150.80444371
53Jak-STAT signaling pathway_Homo sapiens_hsa046300.80117760
54Viral carcinogenesis_Homo sapiens_hsa052030.80019554
55Neurotrophin signaling pathway_Homo sapiens_hsa047220.79290389
56Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.77348406
57Influenza A_Homo sapiens_hsa051640.76247534
58Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.76046430
59Cell cycle_Homo sapiens_hsa041100.73765747
60Pyrimidine metabolism_Homo sapiens_hsa002400.72728789
61Toxoplasmosis_Homo sapiens_hsa051450.70026734
62Legionellosis_Homo sapiens_hsa051340.67761818
63Pancreatic cancer_Homo sapiens_hsa052120.67029530
64NOD-like receptor signaling pathway_Homo sapiens_hsa046210.67026368
65Proteasome_Homo sapiens_hsa030500.65129263
66One carbon pool by folate_Homo sapiens_hsa006700.63537739
67Fructose and mannose metabolism_Homo sapiens_hsa000510.61196545
68Platelet activation_Homo sapiens_hsa046110.61097845
69Allograft rejection_Homo sapiens_hsa053300.59954024
70Other glycan degradation_Homo sapiens_hsa005110.59805085
71Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.59590643
72Malaria_Homo sapiens_hsa051440.56548697
73Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.56334149
74VEGF signaling pathway_Homo sapiens_hsa043700.56006049
75African trypanosomiasis_Homo sapiens_hsa051430.55612385
76Renin-angiotensin system_Homo sapiens_hsa046140.55356490
77Linoleic acid metabolism_Homo sapiens_hsa005910.55330956
78Fat digestion and absorption_Homo sapiens_hsa049750.53404215
79SNARE interactions in vesicular transport_Homo sapiens_hsa041300.52696360
80Glioma_Homo sapiens_hsa052140.51996816
81Pertussis_Homo sapiens_hsa051330.51823073
82Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.50986219
83Arachidonic acid metabolism_Homo sapiens_hsa005900.50324503
84Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.46787157
85MicroRNAs in cancer_Homo sapiens_hsa052060.44475059
86Transcriptional misregulation in cancer_Homo sapiens_hsa052020.44235872
87AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.43866729
88Ether lipid metabolism_Homo sapiens_hsa005650.43423468
89RNA transport_Homo sapiens_hsa030130.42721941
90Drug metabolism - other enzymes_Homo sapiens_hsa009830.42586945
91Pentose phosphate pathway_Homo sapiens_hsa000300.42432336
92Small cell lung cancer_Homo sapiens_hsa052220.41926099
93Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.39048295
94Tryptophan metabolism_Homo sapiens_hsa003800.38784773
95Pancreatic secretion_Homo sapiens_hsa049720.38190159
96RNA degradation_Homo sapiens_hsa030180.38009968
97Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.37471232
98Prostate cancer_Homo sapiens_hsa052150.37176519
99Phagosome_Homo sapiens_hsa041450.36790114
100Phosphatidylinositol signaling system_Homo sapiens_hsa040700.36402496
101TNF signaling pathway_Homo sapiens_hsa046680.36245700
102Systemic lupus erythematosus_Homo sapiens_hsa053220.36193368
103Hepatitis C_Homo sapiens_hsa051600.36043927
104Colorectal cancer_Homo sapiens_hsa052100.34838776
105mRNA surveillance pathway_Homo sapiens_hsa030150.33949988
106Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.33931168
107Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.32872400
108Thyroid hormone synthesis_Homo sapiens_hsa049180.32437635
109Fanconi anemia pathway_Homo sapiens_hsa034600.32375532
110Long-term potentiation_Homo sapiens_hsa047200.30527472
111Cyanoamino acid metabolism_Homo sapiens_hsa004600.30411469
112Folate biosynthesis_Homo sapiens_hsa007900.29785798
113Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.29646271
114Inositol phosphate metabolism_Homo sapiens_hsa005620.29372427
115Carbohydrate digestion and absorption_Homo sapiens_hsa049730.29322976
116Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.29011307
117RNA polymerase_Homo sapiens_hsa030200.27888317
118Peroxisome_Homo sapiens_hsa041460.26733459
119Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.26204565
120Purine metabolism_Homo sapiens_hsa002300.25739649
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.25458502
122Maturity onset diabetes of the young_Homo sapiens_hsa049500.24810290
123mTOR signaling pathway_Homo sapiens_hsa041500.24250659
124Vitamin digestion and absorption_Homo sapiens_hsa049770.22547274
125Steroid hormone biosynthesis_Homo sapiens_hsa001400.22078621
126Sulfur metabolism_Homo sapiens_hsa009200.21843258
127Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.21524835
128Insulin resistance_Homo sapiens_hsa049310.21376793
129Autoimmune thyroid disease_Homo sapiens_hsa053200.20684163
130Glycerolipid metabolism_Homo sapiens_hsa005610.20185793
131Proteoglycans in cancer_Homo sapiens_hsa052050.19165960
132Glycerophospholipid metabolism_Homo sapiens_hsa005640.17811049
133MAPK signaling pathway_Homo sapiens_hsa040100.17804176
134Parkinsons disease_Homo sapiens_hsa050120.17573252
135Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.17142870
136Butanoate metabolism_Homo sapiens_hsa006500.16518319
137Nitrogen metabolism_Homo sapiens_hsa009100.16491078
138Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.16202238

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