MZT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to kinetochore (GO:0034501)5.40217317
2sister chromatid segregation (GO:0000819)5.23945296
3protein localization to chromosome, centromeric region (GO:0071459)5.03389608
4regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.66421734
5positive regulation of mitochondrial calcium ion concentration (GO:0051561)4.13208447
6mitotic chromosome condensation (GO:0007076)4.10482170
7ribosome assembly (GO:0042255)3.96336217
8mitochondrial calcium ion transport (GO:0006851)3.96163928
9spindle checkpoint (GO:0031577)3.94730065
10cullin deneddylation (GO:0010388)3.76424688
11negative regulation of chromosome segregation (GO:0051985)3.74915999
12ribosomal small subunit assembly (GO:0000028)3.72290736
13negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.72281746
14negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.72281746
15negative regulation of mitotic sister chromatid segregation (GO:0033048)3.72281746
16negative regulation of mitotic sister chromatid separation (GO:2000816)3.72281746
17negative regulation of sister chromatid segregation (GO:0033046)3.72281746
18mitotic spindle checkpoint (GO:0071174)3.70952221
19purine nucleobase biosynthetic process (GO:0009113)3.67957453
20regulation of chromosome segregation (GO:0051983)3.65827546
21protein deneddylation (GO:0000338)3.58668667
22spindle assembly checkpoint (GO:0071173)3.58393638
23DNA replication checkpoint (GO:0000076)3.57561402
24mitotic spindle assembly checkpoint (GO:0007094)3.56216271
25nuclear pore organization (GO:0006999)3.54354521
26regulation of mitotic spindle organization (GO:0060236)3.52404649
27CENP-A containing nucleosome assembly (GO:0034080)3.50554684
28regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.49121703
29regulation of mitotic metaphase/anaphase transition (GO:0030071)3.49121703
30establishment of viral latency (GO:0019043)3.47254598
31regulation of sister chromatid segregation (GO:0033045)3.47074658
32regulation of mitotic sister chromatid separation (GO:0010965)3.47074658
33regulation of mitotic sister chromatid segregation (GO:0033047)3.47074658
34regulation of mitochondrial translation (GO:0070129)3.46975987
35nuclear pore complex assembly (GO:0051292)3.45155553
36respiratory chain complex IV assembly (GO:0008535)3.42152325
37chromosome segregation (GO:0007059)3.40663394
38deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.39970270
39mitotic nuclear envelope disassembly (GO:0007077)3.39239079
40ventricular cardiac muscle cell development (GO:0055015)3.37557129
41regulation of spindle organization (GO:0090224)3.36773997
42nucleobase biosynthetic process (GO:0046112)3.30840549
43telomere maintenance via semi-conservative replication (GO:0032201)3.26598616
44positive regulation of chromosome segregation (GO:0051984)3.24368664
45protein K6-linked ubiquitination (GO:0085020)3.22536132
46DNA replication-dependent nucleosome assembly (GO:0006335)3.22320130
47DNA replication-dependent nucleosome organization (GO:0034723)3.22320130
48protein localization to chromosome (GO:0034502)3.22092862
49maturation of 5.8S rRNA (GO:0000460)3.21304092
50chromatin remodeling at centromere (GO:0031055)3.20893177
51folic acid-containing compound biosynthetic process (GO:0009396)3.19401959
52DNA topological change (GO:0006265)3.17358498
53regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.16351373
54establishment of protein localization to mitochondrial membrane (GO:0090151)3.15048481
55membrane disassembly (GO:0030397)3.12180164
56nuclear envelope disassembly (GO:0051081)3.12180164
57DNA replication-independent nucleosome assembly (GO:0006336)3.11783891
58DNA replication-independent nucleosome organization (GO:0034724)3.11783891
59regulation of centrosome cycle (GO:0046605)3.09672305
60regulation of double-strand break repair via homologous recombination (GO:0010569)3.08826296
61negative regulation of mitosis (GO:0045839)3.08654849
62DNA damage response, detection of DNA damage (GO:0042769)3.07785060
63IMP metabolic process (GO:0046040)3.07056778
64histone H2A acetylation (GO:0043968)3.05219272
65negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.05082467
66negative regulation of ligase activity (GO:0051352)3.05082467
67cytochrome complex assembly (GO:0017004)2.98895864
68chromatin assembly or disassembly (GO:0006333)2.98564894
69mitotic cell cycle (GO:0000278)2.97101766
70viral mRNA export from host cell nucleus (GO:0046784)2.96779470
71mitotic sister chromatid cohesion (GO:0007064)2.96583619
72protein complex biogenesis (GO:0070271)2.96315564
73DNA strand elongation involved in DNA replication (GO:0006271)2.95998250
74ATP-dependent chromatin remodeling (GO:0043044)2.95753053
75kinetochore organization (GO:0051383)2.95140037
76L-serine metabolic process (GO:0006563)2.94215380
77ribosomal large subunit biogenesis (GO:0042273)2.91505572
78mitotic G2/M transition checkpoint (GO:0044818)2.89995130
79mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.85752727
80mitochondrial respiratory chain complex I assembly (GO:0032981)2.85752727
81NADH dehydrogenase complex assembly (GO:0010257)2.85752727
82DNA strand elongation (GO:0022616)2.84758485
83telomere maintenance via recombination (GO:0000722)2.83186459
84L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.81808057
85synaptic vesicle exocytosis (GO:0016079)2.79379881
86mitochondrial respiratory chain complex assembly (GO:0033108)2.78425939
87definitive hemopoiesis (GO:0060216)2.75500087
88mitotic recombination (GO:0006312)2.72250438
89deoxyribose phosphate biosynthetic process (GO:0046385)2.71875605
902-deoxyribonucleotide biosynthetic process (GO:0009265)2.71875605
91dopamine transport (GO:0015872)2.67585432
92DNA deamination (GO:0045006)2.66884503
93establishment of integrated proviral latency (GO:0075713)2.65781797
94kinetochore assembly (GO:0051382)2.64296498
95metaphase plate congression (GO:0051310)2.63025225
96establishment of chromosome localization (GO:0051303)2.62811622
97tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.62438363
98RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.62438363
99oxidative phosphorylation (GO:0006119)2.61321698
100postreplication repair (GO:0006301)2.61295721
101mitotic metaphase plate congression (GO:0007080)2.55716502
102inositol phosphate catabolic process (GO:0071545)2.54086674
103DNA replication initiation (GO:0006270)2.53812670
104attachment of spindle microtubules to kinetochore (GO:0008608)2.51887511
105deoxyribonucleotide biosynthetic process (GO:0009263)2.49744565
106DNA ligation (GO:0006266)2.49590476
107negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.48041359
108DNA double-strand break processing (GO:0000729)2.48011292
109histone exchange (GO:0043486)2.47934873
110synaptic vesicle docking involved in exocytosis (GO:0016081)2.43637689
111regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.43313848
112proteasome assembly (GO:0043248)2.42671929
113polyketide metabolic process (GO:0030638)2.41273909
114doxorubicin metabolic process (GO:0044598)2.41273909
115daunorubicin metabolic process (GO:0044597)2.41273909
116anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.41259852
117positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.40820545
118termination of RNA polymerase III transcription (GO:0006386)2.40646273
119transcription elongation from RNA polymerase III promoter (GO:0006385)2.40646273
120telomere maintenance via telomere lengthening (GO:0010833)2.38136119
121protein K11-linked ubiquitination (GO:0070979)2.37088024
122nucleotide-excision repair, DNA gap filling (GO:0006297)2.35864433
123meiotic chromosome segregation (GO:0045132)2.34752413
124DNA unwinding involved in DNA replication (GO:0006268)2.34741920
125metallo-sulfur cluster assembly (GO:0031163)2.33395638
126iron-sulfur cluster assembly (GO:0016226)2.33395638
127peptidyl-histidine modification (GO:0018202)2.32656957
128transport of virus (GO:0046794)2.31597504
129intracellular transport of virus (GO:0075733)2.31597504
130multi-organism transport (GO:0044766)2.31597504
131multi-organism localization (GO:1902579)2.31597504
132multi-organism intracellular transport (GO:1902583)2.31597504
133regulation of synaptic vesicle exocytosis (GO:2000300)2.31226111
134positive regulation of mitochondrial fission (GO:0090141)2.30950466
135de novo posttranslational protein folding (GO:0051084)2.30869105
136de novo protein folding (GO:0006458)2.29119463
137pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.28736569
138chaperone-mediated protein transport (GO:0072321)2.27961903
139L-fucose catabolic process (GO:0042355)2.27037403
140fucose catabolic process (GO:0019317)2.27037403
141L-fucose metabolic process (GO:0042354)2.27037403
142pseudouridine synthesis (GO:0001522)2.26568424
143purine-containing compound salvage (GO:0043101)2.23907479
144catecholamine transport (GO:0051937)2.23627792
145mitotic sister chromatid segregation (GO:0000070)2.23501858
146mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.23129473
147IMP biosynthetic process (GO:0006188)2.22911971
148regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.22501675
149SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.21042796
150regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.21019933
151translesion synthesis (GO:0019985)2.20974581
152cotranslational protein targeting to membrane (GO:0006613)2.19331451
153endosome to melanosome transport (GO:0035646)2.19268951
154endosome to pigment granule transport (GO:0043485)2.19268951
155positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.16980763
156neuronal action potential propagation (GO:0019227)2.16622645
157G1/S transition of mitotic cell cycle (GO:0000082)2.16556168
158cell cycle G1/S phase transition (GO:0044843)2.16556168
1597-methylguanosine RNA capping (GO:0009452)2.16513875
160RNA capping (GO:0036260)2.16513875
161generation of neurons (GO:0048699)2.15124102

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.06305380
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.65317584
3HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.55769600
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.24379284
5NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.19106060
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.03337795
7E2F4_17652178_ChIP-ChIP_JURKAT_Human2.97670967
8EST1_17652178_ChIP-ChIP_JURKAT_Human2.97263498
9EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.87147831
10RBPJ_22232070_ChIP-Seq_NCS_Mouse2.83918275
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.80524466
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.72860075
13MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.61272410
14HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.59282168
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.51223859
16THAP11_20581084_ChIP-Seq_MESCs_Mouse2.49490880
17PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.35891621
18* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.33785346
19VDR_23849224_ChIP-Seq_CD4+_Human2.32902313
20CREB1_15753290_ChIP-ChIP_HEK293T_Human2.26870214
21* FOXM1_23109430_ChIP-Seq_U2OS_Human2.24461829
22HOXB4_20404135_ChIP-ChIP_EML_Mouse2.23259835
23* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.21285825
24HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.20484023
25MYC_18358816_ChIP-ChIP_MESCs_Mouse2.17551706
26ELK1_19687146_ChIP-ChIP_HELA_Human2.17001488
27MYC_19030024_ChIP-ChIP_MESCs_Mouse2.12875825
28E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.08784991
29CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.08361817
30* FOXP3_21729870_ChIP-Seq_TREG_Human1.97708013
31YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.95220189
32SRF_21415370_ChIP-Seq_HL-1_Mouse1.92611109
33NELFA_20434984_ChIP-Seq_ESCs_Mouse1.84524524
34SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.84372924
35PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.83024974
36E2F1_18555785_ChIP-Seq_MESCs_Mouse1.81244102
37DCP1A_22483619_ChIP-Seq_HELA_Human1.79967606
38TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.77621613
39MYC_19079543_ChIP-ChIP_MESCs_Mouse1.74124348
40FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.70283677
41EZH2_22144423_ChIP-Seq_EOC_Human1.69792408
42XRN2_22483619_ChIP-Seq_HELA_Human1.69404548
43GABP_19822575_ChIP-Seq_HepG2_Human1.68872328
44ERG_20887958_ChIP-Seq_HPC-7_Mouse1.64735479
45ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.62587897
46TTF2_22483619_ChIP-Seq_HELA_Human1.61560085
47ZFX_18555785_ChIP-Seq_MESCs_Mouse1.56396069
48EWS_26573619_Chip-Seq_HEK293_Human1.54729927
49CIITA_25753668_ChIP-Seq_RAJI_Human1.51314664
50TAF15_26573619_Chip-Seq_HEK293_Human1.48336462
51GBX2_23144817_ChIP-Seq_PC3_Human1.47885387
52MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.47877597
53E2F1_21310950_ChIP-Seq_MCF-7_Human1.47851873
54FUS_26573619_Chip-Seq_HEK293_Human1.44977435
55POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.44362215
56POU3F2_20337985_ChIP-ChIP_501MEL_Human1.42882237
57CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.42507680
58PADI4_21655091_ChIP-ChIP_MCF-7_Human1.41591700
59SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.40019219
60YY1_21170310_ChIP-Seq_MESCs_Mouse1.39818552
61GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.39543559
62PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.38727130
63KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.37344441
64MYCN_18555785_ChIP-Seq_MESCs_Mouse1.36573940
65MYC_18940864_ChIP-ChIP_HL60_Human1.35130290
66IGF1R_20145208_ChIP-Seq_DFB_Human1.28991146
67NANOG_18555785_ChIP-Seq_MESCs_Mouse1.26516892
68TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.14274193
69CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.11998733
70GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11132070
71SALL1_21062744_ChIP-ChIP_HESCs_Human1.08035939
72NOTCH1_21737748_ChIP-Seq_TLL_Human1.07356829
73ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.07252186
74CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.07187622
75ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.06683032
76TP63_19390658_ChIP-ChIP_HaCaT_Human0.99068616
77NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.98951695
78NANOG_16153702_ChIP-ChIP_HESCs_Human0.98825829
79SCL_19346495_ChIP-Seq_HPC-7_Human0.98300910
80IRF1_19129219_ChIP-ChIP_H3396_Human0.98068950
81E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.96748532
82SOX17_20123909_ChIP-Seq_XEN_Mouse0.96284135
83GATA1_22025678_ChIP-Seq_K562_Human0.95962965
84SOX2_16153702_ChIP-ChIP_HESCs_Human0.95297608
85POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.95019353
86MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.94208841
87KLF4_18555785_ChIP-Seq_MESCs_Mouse0.93560497
88CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.92998493
89MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.90844680
90SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.90525061
91SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.90414104
92AR_21909140_ChIP-Seq_LNCAP_Human0.88332234
93NANOG_21062744_ChIP-ChIP_HESCs_Human0.88124010
94KDM5A_27292631_Chip-Seq_BREAST_Human0.87111694
95CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.87078803
96LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.86125602
97CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.85897737
98P300_19829295_ChIP-Seq_ESCs_Human0.85720054
99RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.85695999
100BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.85075207
101POU5F1_16153702_ChIP-ChIP_HESCs_Human0.84062263
102SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.83756963
103CTBP2_25329375_ChIP-Seq_LNCAP_Human0.83641056
104SOX2_18555785_ChIP-Seq_MESCs_Mouse0.83599713
105FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.83287682
106FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.83104790
107REST_19997604_ChIP-ChIP_NEURONS_Mouse0.82764788
108KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.82122262
109SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.81597577
110TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.81423920
111REST_18959480_ChIP-ChIP_MESCs_Mouse0.80993439
112NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.79901159
113SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.79736696
114CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.79181458
115ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.78427437
116CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.78032380
117TFEB_21752829_ChIP-Seq_HELA_Human0.77981246
118POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.77664833
119HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.77489491
120MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.77046824
121CHD1_26751641_Chip-Seq_LNCaP_Human0.73392699
122VDR_22108803_ChIP-Seq_LS180_Human0.72805597
123ELK1_22589737_ChIP-Seq_MCF10A_Human0.70696790

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001188_hyperpigmentation3.51135300
2MP0003880_abnormal_central_pattern2.83777261
3MP0006292_abnormal_olfactory_placode2.64079990
4MP0010094_abnormal_chromosome_stability2.56206639
5MP0004859_abnormal_synaptic_plasticity2.50143874
6MP0003693_abnormal_embryo_hatching2.45632881
7MP0003122_maternal_imprinting2.42691711
8MP0004147_increased_porphyrin_level2.34728032
9MP0001529_abnormal_vocalization2.24258628
10MP0008007_abnormal_cellular_replicative2.08174795
11MP0003787_abnormal_imprinting2.01843478
12MP0003635_abnormal_synaptic_transmissio2.01232664
13MP0005646_abnormal_pituitary_gland2.01067464
14MP0008058_abnormal_DNA_repair1.97500231
15MP0002396_abnormal_hematopoietic_system1.96834757
16MP0003123_paternal_imprinting1.96321887
17MP0000350_abnormal_cell_proliferation1.95330422
18MP0001968_abnormal_touch/_nociception1.91948686
19MP0003121_genomic_imprinting1.91656493
20MP0004957_abnormal_blastocyst_morpholog1.89425866
21MP0003077_abnormal_cell_cycle1.86314322
22MP0001730_embryonic_growth_arrest1.86002384
23MP0006276_abnormal_autonomic_nervous1.79605995
24MP0009745_abnormal_behavioral_response1.75319621
25MP0003111_abnormal_nucleus_morphology1.74786122
26MP0002063_abnormal_learning/memory/cond1.72347298
27MP0010352_gastrointestinal_tract_polyps1.69958254
28MP0003806_abnormal_nucleotide_metabolis1.68637692
29MP0003718_maternal_effect1.68034327
30MP0008057_abnormal_DNA_replication1.67332842
31MP0001293_anophthalmia1.66970901
32MP0002736_abnormal_nociception_after1.65480766
33MP0001346_abnormal_lacrimal_gland1.65022081
34MP0003941_abnormal_skin_development1.61000688
35MP0002638_abnormal_pupillary_reflex1.59049545
36MP0000631_abnormal_neuroendocrine_gland1.58608074
37MP0009379_abnormal_foot_pigmentation1.57748461
38MP0005645_abnormal_hypothalamus_physiol1.57549797
39MP0001697_abnormal_embryo_size1.56348340
40MP0001986_abnormal_taste_sensitivity1.56239895
41MP0002822_catalepsy1.55052580
42MP0006054_spinal_hemorrhage1.54468566
43MP0004808_abnormal_hematopoietic_stem1.51383588
44MP0002734_abnormal_mechanical_nocicepti1.49889292
45MP0001672_abnormal_embryogenesis/_devel1.49832300
46MP0005380_embryogenesis_phenotype1.49832300
47MP0003937_abnormal_limbs/digits/tail_de1.49265986
48MP0001905_abnormal_dopamine_level1.49244929
49MP0010386_abnormal_urinary_bladder1.46911562
50MP0002272_abnormal_nervous_system1.46044881
51MP0002572_abnormal_emotion/affect_behav1.39852232
52MP0005187_abnormal_penis_morphology1.39356635
53MP0002085_abnormal_embryonic_tissue1.38737773
54MP0005409_darkened_coat_color1.37044503
55MP0002064_seizures1.34943650
56MP0003890_abnormal_embryonic-extraembry1.34810411
57MP0004270_analgesia1.34673510
58MP0002095_abnormal_skin_pigmentation1.32789953
59MP0000015_abnormal_ear_pigmentation1.30614526
60MP0003136_yellow_coat_color1.29613861
61MP0002080_prenatal_lethality1.28647571
62MP0002084_abnormal_developmental_patter1.28349721
63MP0002160_abnormal_reproductive_system1.26623264
64MP0001984_abnormal_olfaction1.25802137
65MP0002009_preneoplasia1.25786793
66MP0003984_embryonic_growth_retardation1.25572436
67MP0004811_abnormal_neuron_physiology1.23865406
68MP0003183_abnormal_peptide_metabolism1.20237996
69MP0002877_abnormal_melanocyte_morpholog1.20109868
70MP0004215_abnormal_myocardial_fiber1.19987266
71MP0002735_abnormal_chemical_nociception1.19413323
72MP0005623_abnormal_meninges_morphology1.19107774
73MP0010307_abnormal_tumor_latency1.18584836
74MP0002088_abnormal_embryonic_growth/wei1.18523301
75MP0003879_abnormal_hair_cell1.17194649
76MP0002184_abnormal_innervation1.14477855
77MP0002210_abnormal_sex_determination1.14301094
78MP0006036_abnormal_mitochondrial_physio1.13283190
79MP0002697_abnormal_eye_size1.13220335
80MP0003186_abnormal_redox_activity1.11398995
81MP0008877_abnormal_DNA_methylation1.09229120
82MP0001545_abnormal_hematopoietic_system1.09082258
83MP0005397_hematopoietic_system_phenotyp1.09082258
84MP0001929_abnormal_gametogenesis1.08433636
85MP0002751_abnormal_autonomic_nervous1.08288335
86MP0010030_abnormal_orbit_morphology1.07968593
87MP0000490_abnormal_crypts_of1.07356387
88MP0006035_abnormal_mitochondrial_morpho1.07207526
89MP0002233_abnormal_nose_morphology1.06414062
90MP0002102_abnormal_ear_morphology1.05061936
91MP0002557_abnormal_social/conspecific_i1.04771175
92MP0000358_abnormal_cell_content/1.04020911
93MP0003567_abnormal_fetal_cardiomyocyte1.03571635
94MP0009046_muscle_twitch1.03457975
95MP0009672_abnormal_birth_weight1.03177990
96MP0005174_abnormal_tail_pigmentation1.01972241
97MP0004197_abnormal_fetal_growth/weight/1.01380609
98MP0002163_abnormal_gland_morphology1.01055639
99MP0005379_endocrine/exocrine_gland_phen1.00549512
100MP0003943_abnormal_hepatobiliary_system1.00263981
101MP0001286_abnormal_eye_development1.00219819
102MP0002909_abnormal_adrenal_gland0.99460992
103MP0001145_abnormal_male_reproductive0.98628389
104MP0001970_abnormal_pain_threshold0.98350971
105MP0002067_abnormal_sensory_capabilities0.97803868
106MP0008932_abnormal_embryonic_tissue0.97263341
107MP0001299_abnormal_eye_distance/0.96514082
108MP0006072_abnormal_retinal_apoptosis0.95443133
109MP0004924_abnormal_behavior0.95205208
110MP0005386_behavior/neurological_phenoty0.95205208
111MP0000653_abnormal_sex_gland0.93502943
112MP0004142_abnormal_muscle_tone0.92642273
113MP0002177_abnormal_outer_ear0.92431375
114MP0000681_abnormal_thyroid_gland0.92404840
115MP0002090_abnormal_vision0.92115393
116MP0002086_abnormal_extraembryonic_tissu0.90806134
117MP0008789_abnormal_olfactory_epithelium0.89746579
118MP0001727_abnormal_embryo_implantation0.89607567
119MP0002733_abnormal_thermal_nociception0.89468974
120MP0000647_abnormal_sebaceous_gland0.89123193
121MP0003646_muscle_fatigue0.89086263
122MP0005084_abnormal_gallbladder_morpholo0.87840488
123MP0005423_abnormal_somatic_nervous0.85641132
124MP0001501_abnormal_sleep_pattern0.85366679
125MP0005171_absent_coat_pigmentation0.85184000
126MP0000372_irregular_coat_pigmentation0.84759443
127MP0010234_abnormal_vibrissa_follicle0.82505911
128MP0003763_abnormal_thymus_physiology0.82112689
129MP0005394_taste/olfaction_phenotype0.80845703
130MP0005499_abnormal_olfactory_system0.80845703
131MP0002653_abnormal_ependyma_morphology0.80688956
132MP0008569_lethality_at_weaning0.80594859
133MP0003786_premature_aging0.79878571
134MP0001764_abnormal_homeostasis0.79103882
135MP0003755_abnormal_palate_morphology0.78399301
136MP0003221_abnormal_cardiomyocyte_apopto0.78354403
137MP0004145_abnormal_muscle_electrophysio0.75249331
138MP0008995_early_reproductive_senescence0.74628381
139MP0003698_abnormal_male_reproductive0.74186409
140MP0005671_abnormal_response_to0.73411788
141MP0002938_white_spotting0.72568088
142MP0002693_abnormal_pancreas_physiology0.71802452
143MP0002234_abnormal_pharynx_morphology0.71679274
144MP0001919_abnormal_reproductive_system0.71591566
145MP0000751_myopathy0.71434482
146MP0003861_abnormal_nervous_system0.71347803
147MP0001486_abnormal_startle_reflex0.70918334
148MP0002092_abnormal_eye_morphology0.70839517
149MP0009250_abnormal_appendicular_skeleto0.70252766
150MP0000313_abnormal_cell_death0.70123760
151MP0002398_abnormal_bone_marrow0.69784062
152MP0002837_dystrophic_cardiac_calcinosis0.69476420
153MP0009697_abnormal_copulation0.68732093
154MP0003119_abnormal_digestive_system0.68604223
155MP0003315_abnormal_perineum_morphology0.68573546
156MP0005391_vision/eye_phenotype0.67954412
157MP0001119_abnormal_female_reproductive0.67459974
158MP0005253_abnormal_eye_physiology0.67190032
159MP0003942_abnormal_urinary_system0.65946618
160MP0002111_abnormal_tail_morphology0.65207637
161MP0004233_abnormal_muscle_weight0.64693026
162MP0000049_abnormal_middle_ear0.64529122
163MP0002161_abnormal_fertility/fecundity0.63227222
164MP0005389_reproductive_system_phenotype0.62533967
165MP0003935_abnormal_craniofacial_develop0.61632173

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.08952339
2Hypothermia (HP:0002045)3.94710739
3Chromsome breakage (HP:0040012)3.80298197
4Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.75053572
5Abnormality of alanine metabolism (HP:0010916)3.75053572
6Hyperalaninemia (HP:0003348)3.75053572
7Focal motor seizures (HP:0011153)3.67731828
8Abnormality of the heme biosynthetic pathway (HP:0010472)3.67065148
9Abnormal lung lobation (HP:0002101)3.62529054
10Type I transferrin isoform profile (HP:0003642)3.52888557
11Aplastic anemia (HP:0001915)3.44505071
12Increased serum pyruvate (HP:0003542)3.30960304
13Pancreatic islet-cell hyperplasia (HP:0004510)3.29101387
14Abnormality of glycolysis (HP:0004366)3.26959709
15Abnormal hair whorl (HP:0010721)3.11454191
16Abnormal number of erythroid precursors (HP:0012131)3.09035109
17Meckel diverticulum (HP:0002245)2.98405777
18Abnormal mitochondria in muscle tissue (HP:0008316)2.95763097
19Abnormality of cells of the erythroid lineage (HP:0012130)2.95649585
20Neuroendocrine neoplasm (HP:0100634)2.93845414
21Abnormality of chromosome stability (HP:0003220)2.88882202
22Abnormality of the ileum (HP:0001549)2.85848185
23Acute necrotizing encephalopathy (HP:0006965)2.84438987
24Cortical dysplasia (HP:0002539)2.79713411
25Aplasia/Hypoplasia of the uvula (HP:0010293)2.79240008
26Mitochondrial inheritance (HP:0001427)2.74155188
27Abnormality of the preputium (HP:0100587)2.73733858
28Hepatocellular necrosis (HP:0001404)2.71484136
29Duodenal stenosis (HP:0100867)2.70207025
30Small intestinal stenosis (HP:0012848)2.70207025
31Visual hallucinations (HP:0002367)2.65043589
32Lissencephaly (HP:0001339)2.63068270
33Aplasia/Hypoplasia of the sacrum (HP:0008517)2.60934601
34Multiple enchondromatosis (HP:0005701)2.58232318
35Birth length less than 3rd percentile (HP:0003561)2.55639891
36Reticulocytopenia (HP:0001896)2.55285191
37Protruding tongue (HP:0010808)2.54326551
38Epileptic encephalopathy (HP:0200134)2.51503686
39Increased CSF lactate (HP:0002490)2.49325402
40Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.46509679
41Abnormal protein N-linked glycosylation (HP:0012347)2.46509679
42Abnormal protein glycosylation (HP:0012346)2.46509679
43Abnormal glycosylation (HP:0012345)2.46509679
44Febrile seizures (HP:0002373)2.45931135
45Abnormality of the anterior horn cell (HP:0006802)2.43283556
46Degeneration of anterior horn cells (HP:0002398)2.43283556
47Increased nuchal translucency (HP:0010880)2.40145825
48Atonic seizures (HP:0010819)2.39339716
49Poor suck (HP:0002033)2.38846260
50Progressive macrocephaly (HP:0004481)2.38675012
51Pheochromocytoma (HP:0002666)2.36620634
52Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.36495223
53Decreased activity of mitochondrial respiratory chain (HP:0008972)2.36495223
54Cutaneous melanoma (HP:0012056)2.35353250
55Abnormal umbilical cord blood vessels (HP:0011403)2.35188656
56Single umbilical artery (HP:0001195)2.35188656
57Abnormality of the fetal cardiovascular system (HP:0010948)2.35188656
58Shoulder girdle muscle weakness (HP:0003547)2.32069528
59Pancreatic fibrosis (HP:0100732)2.30572374
60True hermaphroditism (HP:0010459)2.27339576
61Capillary hemangiomas (HP:0005306)2.27103225
62Abnormality of the duodenum (HP:0002246)2.26476786
63Increased hepatocellular lipid droplets (HP:0006565)2.25617943
64Hyperinsulinemic hypoglycemia (HP:0000825)2.22035415
65Short middle phalanx of the 5th finger (HP:0004220)2.21075806
66Hypoglycemic coma (HP:0001325)2.19825836
67Limb dystonia (HP:0002451)2.18421354
68Type 2 muscle fiber atrophy (HP:0003554)2.18393472
69Irregular epiphyses (HP:0010582)2.17113288
70Cerebral edema (HP:0002181)2.16682491
71Type II lissencephaly (HP:0007260)2.16503248
72Abnormality of the pancreatic islet cells (HP:0006476)2.16179662
73Abnormality of endocrine pancreas physiology (HP:0012093)2.16179662
74Papilledema (HP:0001085)2.14602794
75Absent radius (HP:0003974)2.14601154
76Hypoglycemic seizures (HP:0002173)2.13652756
77Triphalangeal thumb (HP:0001199)2.12877832
78Hepatic necrosis (HP:0002605)2.12838679
79Muscle fiber atrophy (HP:0100295)2.11432542
803-Methylglutaconic aciduria (HP:0003535)2.10682604
81Neoplasm of the adrenal gland (HP:0100631)2.08770097
82Pancreatic cysts (HP:0001737)2.08655073
83Increased serum lactate (HP:0002151)2.07055993
84Ectopic kidney (HP:0000086)2.06109320
85Myelodysplasia (HP:0002863)2.04243654
86Reduced antithrombin III activity (HP:0001976)2.03852964
87Exercise-induced muscle cramps (HP:0003710)2.01778252
88Hypoplasia of the pons (HP:0012110)1.99607089
89Nephrogenic diabetes insipidus (HP:0009806)1.99476862
90Progressive inability to walk (HP:0002505)1.99416371
91Aplasia involving forearm bones (HP:0009822)1.99140536
92Absent forearm bone (HP:0003953)1.99140536
93Tinnitus (HP:0000360)1.98998251
94Neoplasm of the peripheral nervous system (HP:0100007)1.98585000
95Progressive muscle weakness (HP:0003323)1.97476342
96Sloping forehead (HP:0000340)1.96934827
97Microvesicular hepatic steatosis (HP:0001414)1.96774281
98Unsteady gait (HP:0002317)1.96613104
99Abnormality of methionine metabolism (HP:0010901)1.96126273
100Abnormality of the umbilical cord (HP:0010881)1.95307475
101Gait imbalance (HP:0002141)1.92577131
102Lipid accumulation in hepatocytes (HP:0006561)1.91426334
103Abnormality of the carotid arteries (HP:0005344)1.91219536
104Myokymia (HP:0002411)1.90257148
105Acute encephalopathy (HP:0006846)1.89030846
106Abnormality of midbrain morphology (HP:0002418)1.88994968
107Molar tooth sign on MRI (HP:0002419)1.88994968
108Mutism (HP:0002300)1.87859496
109Septate vagina (HP:0001153)1.87543059
110Medial flaring of the eyebrow (HP:0010747)1.87362399
111Abnormality of homocysteine metabolism (HP:0010919)1.86697360
112Homocystinuria (HP:0002156)1.86697360
113Lactic acidosis (HP:0003128)1.86165286
114Abnormality of the labia minora (HP:0012880)1.85485447
115Exercise intolerance (HP:0003546)1.84479067
116Deep philtrum (HP:0002002)1.84349108
117Congenital primary aphakia (HP:0007707)1.84271874
118Cafe-au-lait spot (HP:0000957)1.84050145
119Thrombocytosis (HP:0001894)1.83055109
120Fetal akinesia sequence (HP:0001989)1.82992296
121Colon cancer (HP:0003003)1.82632411
12211 pairs of ribs (HP:0000878)1.82060618
123Menstrual irregularities (HP:0000858)1.80272834
124Rimmed vacuoles (HP:0003805)1.79815118
125Arteriovenous malformation (HP:0100026)1.79331264
126Macrocytic anemia (HP:0001972)1.79268779
127Papillary thyroid carcinoma (HP:0002895)1.79207568
128Thyroid carcinoma (HP:0002890)1.78869182
129Impaired vibration sensation in the lower limbs (HP:0002166)1.78406082
130Progressive external ophthalmoplegia (HP:0000590)1.76367821
131Atrophy/Degeneration involving motor neurons (HP:0007373)1.76339317
132Neoplasm of the colon (HP:0100273)1.76289810
133Abnormality of the pons (HP:0007361)1.75259827
134Broad-based gait (HP:0002136)1.74756963
135Sensory axonal neuropathy (HP:0003390)1.74732305
136Horseshoe kidney (HP:0000085)1.74193892
137Abnormal number of incisors (HP:0011064)1.73535365
138Medulloblastoma (HP:0002885)1.73505035
139Nephroblastoma (Wilms tumor) (HP:0002667)1.73349876
140Renal Fanconi syndrome (HP:0001994)1.73092746
141Retinal dysplasia (HP:0007973)1.73068568
142Leukodystrophy (HP:0002415)1.72782823
143Truncal ataxia (HP:0002078)1.71792995
144Anxiety (HP:0000739)1.71503529
145Petechiae (HP:0000967)1.71462159
146Confusion (HP:0001289)1.71239789
147Pancytopenia (HP:0001876)1.71110108
148Facial cleft (HP:0002006)1.70699571
149Volvulus (HP:0002580)1.70670148
150Pelvic girdle muscle weakness (HP:0003749)1.70583446
151Severe visual impairment (HP:0001141)1.70248723
152Selective tooth agenesis (HP:0001592)1.69902580
153Spinal canal stenosis (HP:0003416)1.68604309
154Pallor (HP:0000980)1.67789909
155Neuroblastoma (HP:0003006)1.66170736
156Primitive neuroectodermal tumor (HP:0030065)1.66170736
157Neuroblastic tumors (HP:0004376)1.66170736
158Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.66170736
159Muscular hypotonia of the trunk (HP:0008936)1.64440836
160Abnormality of the hip-girdle musculature (HP:0001445)1.63501714
161Abnormality of the musculature of the pelvis (HP:0001469)1.63501714
162Acute lymphatic leukemia (HP:0006721)1.62541243
163Embryonal renal neoplasm (HP:0011794)1.62124979
164Generalized tonic-clonic seizures (HP:0002069)1.62102940
165Absence seizures (HP:0002121)1.61912967
166Heterochromia iridis (HP:0001100)1.61400393

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K124.07365030
2STK163.63073505
3VRK23.38841155
4TTK3.05917738
5TNIK2.97330658
6CCNB12.85423876
7MAP2K72.67444237
8PLK42.52735620
9PBK2.40771929
10ERBB32.36414804
11SIK32.35380786
12CDK192.34533333
13CASK2.30911499
14TRIM282.19675912
15NTRK32.19184346
16TSSK62.14327404
17STK31.97668302
18MAPK131.97268058
19VRK11.95311920
20WEE11.90190079
21BUB11.90141943
22MST41.89262132
23EIF2AK11.79480392
24NEK11.78462972
25DAPK11.73815181
26ACVR1B1.68570384
27CDC71.67888244
28BRSK11.64356606
29BRSK21.64261625
30TAF11.56827791
31LATS11.56665563
32MKNK11.54809541
33CDK81.49943010
34MAP3K41.48429791
35UHMK11.46073825
36MINK11.43864137
37NUAK11.39026912
38EIF2AK31.38502075
39PASK1.34498515
40SCYL21.33155526
41PLK31.31784370
42PRPF4B1.31616221
43CAMKK21.28054838
44NME21.21840864
45TGFBR11.17688119
46KSR11.14888200
47BRAF1.14720519
48SRPK11.11623140
49ARAF1.11276791
50YES11.08320804
51CLK11.04883675
52MARK10.98450619
53PLK10.96684788
54PLK20.96396310
55CDK70.95703441
56EPHA40.93688781
57TEC0.92703061
58ADRBK20.91713507
59RAF10.91482344
60MKNK20.88304315
61PIM20.87471801
62FLT30.87362435
63MAP3K80.86973826
64DYRK30.85719594
65AKT30.85600514
66CHEK10.83929561
67MAP2K40.82588281
68BMPR20.79695526
69ZAK0.75971620
70MUSK0.75515440
71MAPKAPK50.74707676
72ATR0.72375085
73MAP3K90.72256130
74BMPR1B0.71999689
75MAPKAPK30.69853645
76PDK20.69360080
77DYRK20.68753244
78CSNK1G10.66548694
79ATM0.66166685
80EIF2AK20.65582433
81NEK20.64302031
82TIE10.63708876
83CDK180.63690118
84LIMK10.63684712
85STK38L0.62742892
86STK40.62368517
87SGK20.61398162
88INSRR0.61217427
89ALK0.59636871
90GRK50.59082968
91TXK0.58200544
92RPS6KB10.57994538
93AURKB0.57383524
94KIT0.57116149
95AURKA0.56230566
96WNK30.55540715
97CDK30.55249344
98MAP3K60.54941486
99CDK10.54655738
100NME10.53644461
101CSNK1A1L0.53640141
102TAOK20.52713043
103HIPK20.51853055
104STK240.51374448
105CSNK2A10.51335402
106TESK20.51049267
107CDK140.50979087
108CDK11A0.50303532
109CDK150.49527262
110BCR0.49052216
111CDK50.48421540
112CAMKK10.47693181
113TNK20.46415960
114PNCK0.46045131
115PAK40.45243711
116BRD40.43384279
117CSNK2A20.43356096
118CDK60.42929032
119CSNK1G30.42064895
120RPS6KB20.41702001
121CDK20.41507574
122AKT20.40436174
123ADRBK10.39771328
124CHEK20.39463266
125MYLK0.38706774
126DYRK1A0.37960493
127TLK10.36268700
128PRKCG0.35848826
129SYK0.35539157
130LATS20.34066812
131STK100.32630725
132BTK0.31736509
133RPS6KA40.30792719
134CSNK1E0.30714954
135MATK0.30660393
136CSNK1G20.30491051
137CDK40.30392889
138MAP3K100.30371343
139NTRK20.30160168
140IRAK40.29579345
141RPS6KA50.27711063
142BCKDK0.26313616
143ERBB40.26295929
144GRK70.26222318
145FGFR10.25043012
146PAK10.23633051

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.33808928
2Mismatch repair_Homo sapiens_hsa034302.63557938
3One carbon pool by folate_Homo sapiens_hsa006702.41766050
4Proteasome_Homo sapiens_hsa030502.16194149
5Ribosome_Homo sapiens_hsa030102.12880507
6RNA polymerase_Homo sapiens_hsa030202.07975944
7Protein export_Homo sapiens_hsa030602.05426233
8Homologous recombination_Homo sapiens_hsa034402.03181234
9Base excision repair_Homo sapiens_hsa034102.02368791
10Spliceosome_Homo sapiens_hsa030401.93675120
11Synaptic vesicle cycle_Homo sapiens_hsa047211.89864204
12Parkinsons disease_Homo sapiens_hsa050121.79293385
13Cell cycle_Homo sapiens_hsa041101.77328446
14Nicotine addiction_Homo sapiens_hsa050331.77280216
15Nucleotide excision repair_Homo sapiens_hsa034201.76012281
16SNARE interactions in vesicular transport_Homo sapiens_hsa041301.75112174
17Olfactory transduction_Homo sapiens_hsa047401.65233649
18Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.64032382
19Pyrimidine metabolism_Homo sapiens_hsa002401.61124576
20Cysteine and methionine metabolism_Homo sapiens_hsa002701.60467981
21Folate biosynthesis_Homo sapiens_hsa007901.58898536
22Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.58664860
23Oxidative phosphorylation_Homo sapiens_hsa001901.58175648
24RNA transport_Homo sapiens_hsa030131.48290743
25Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.46848701
26Oocyte meiosis_Homo sapiens_hsa041141.41325640
27RNA degradation_Homo sapiens_hsa030181.38979527
28Amphetamine addiction_Homo sapiens_hsa050311.36659079
29Pyruvate metabolism_Homo sapiens_hsa006201.35064405
30Vibrio cholerae infection_Homo sapiens_hsa051101.32938429
31Vitamin B6 metabolism_Homo sapiens_hsa007501.32808398
32Dopaminergic synapse_Homo sapiens_hsa047281.32100311
33Non-homologous end-joining_Homo sapiens_hsa034501.30569912
34Fanconi anemia pathway_Homo sapiens_hsa034601.30444962
35Basal transcription factors_Homo sapiens_hsa030221.29310441
36Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.27765155
37Biosynthesis of amino acids_Homo sapiens_hsa012301.26197438
38Thyroid cancer_Homo sapiens_hsa052161.25328607
39Alcoholism_Homo sapiens_hsa050341.25065151
40Long-term potentiation_Homo sapiens_hsa047201.24579161
41Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.23749331
42Sulfur relay system_Homo sapiens_hsa041221.23010142
43Circadian entrainment_Homo sapiens_hsa047131.21753238
44Morphine addiction_Homo sapiens_hsa050321.20803870
452-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.18231500
46Purine metabolism_Homo sapiens_hsa002301.18067630
47Collecting duct acid secretion_Homo sapiens_hsa049661.14572320
48Propanoate metabolism_Homo sapiens_hsa006401.13904594
49Huntingtons disease_Homo sapiens_hsa050161.13770526
50Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.13177044
51N-Glycan biosynthesis_Homo sapiens_hsa005101.12900309
52Serotonergic synapse_Homo sapiens_hsa047261.07780880
53Sulfur metabolism_Homo sapiens_hsa009201.07777735
54GABAergic synapse_Homo sapiens_hsa047271.06577666
55Fatty acid elongation_Homo sapiens_hsa000621.04808302
56Taste transduction_Homo sapiens_hsa047421.04444005
57Alzheimers disease_Homo sapiens_hsa050101.02159124
58Type I diabetes mellitus_Homo sapiens_hsa049400.99445143
59Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.97656760
60Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.97602097
61Carbon metabolism_Homo sapiens_hsa012000.97058702
62mRNA surveillance pathway_Homo sapiens_hsa030150.96826586
63Insulin secretion_Homo sapiens_hsa049110.92410163
64Selenocompound metabolism_Homo sapiens_hsa004500.91443721
65Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.90243993
66Cocaine addiction_Homo sapiens_hsa050300.85908619
67Glutamatergic synapse_Homo sapiens_hsa047240.85569878
68Cholinergic synapse_Homo sapiens_hsa047250.83186480
69Regulation of autophagy_Homo sapiens_hsa041400.82465880
70Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.81707128
71Steroid biosynthesis_Homo sapiens_hsa001000.81516756
72Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.79728839
73p53 signaling pathway_Homo sapiens_hsa041150.78873002
74Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.75414523
75Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.72867390
76Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.72829031
77Colorectal cancer_Homo sapiens_hsa052100.72282839
78Calcium signaling pathway_Homo sapiens_hsa040200.72044203
79Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.71980320
80Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.70894165
81Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.70431215
82Epstein-Barr virus infection_Homo sapiens_hsa051690.69459527
83Long-term depression_Homo sapiens_hsa047300.68174130
84Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.68116673
85Legionellosis_Homo sapiens_hsa051340.66447025
86Cardiac muscle contraction_Homo sapiens_hsa042600.66379380
87Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.63501857
88Circadian rhythm_Homo sapiens_hsa047100.60468289
89Glutathione metabolism_Homo sapiens_hsa004800.60323693
90Oxytocin signaling pathway_Homo sapiens_hsa049210.59925459
91Gap junction_Homo sapiens_hsa045400.59816784
92Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.57087662
93Aldosterone synthesis and secretion_Homo sapiens_hsa049250.56448870
94Metabolic pathways_Homo sapiens_hsa011000.56340484
95Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.54658735
96Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.54262238
97Shigellosis_Homo sapiens_hsa051310.52449964
98Hippo signaling pathway_Homo sapiens_hsa043900.50725741
99Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.48995295
100Neurotrophin signaling pathway_Homo sapiens_hsa047220.48749616
101Systemic lupus erythematosus_Homo sapiens_hsa053220.47508989
102Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47279366
103Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.46730878
104Rheumatoid arthritis_Homo sapiens_hsa053230.45861685
105Pentose phosphate pathway_Homo sapiens_hsa000300.44285140
106TGF-beta signaling pathway_Homo sapiens_hsa043500.44063501
107Herpes simplex infection_Homo sapiens_hsa051680.43541151
108Phagosome_Homo sapiens_hsa041450.41523742
109Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.40562641
110Transcriptional misregulation in cancer_Homo sapiens_hsa052020.40258637
111Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.39455107
112Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.39446500
113Viral carcinogenesis_Homo sapiens_hsa052030.38671203
114Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.38083039
115Renin secretion_Homo sapiens_hsa049240.36824536
116Hedgehog signaling pathway_Homo sapiens_hsa043400.34341035
117Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.33699721
118Hepatitis B_Homo sapiens_hsa051610.33628986
119GnRH signaling pathway_Homo sapiens_hsa049120.33156698
120Non-small cell lung cancer_Homo sapiens_hsa052230.33154005
121Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.33066943
122Glioma_Homo sapiens_hsa052140.31606529
123Vitamin digestion and absorption_Homo sapiens_hsa049770.29359948
124Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.29174044
125cAMP signaling pathway_Homo sapiens_hsa040240.28815065
126Gastric acid secretion_Homo sapiens_hsa049710.28719792
127ErbB signaling pathway_Homo sapiens_hsa040120.28641588
128Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.28529637
129Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.28024134
130Platelet activation_Homo sapiens_hsa046110.27042166
131Salivary secretion_Homo sapiens_hsa049700.26684033
132Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.25683281
133Arginine and proline metabolism_Homo sapiens_hsa003300.24590832
134Wnt signaling pathway_Homo sapiens_hsa043100.24072734
135Bladder cancer_Homo sapiens_hsa052190.19203191
136Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.19074702
137MicroRNAs in cancer_Homo sapiens_hsa052060.18641013
138Basal cell carcinoma_Homo sapiens_hsa052170.15875354
139Melanoma_Homo sapiens_hsa052180.15473050
140Lysine degradation_Homo sapiens_hsa003100.12712529
141Fatty acid metabolism_Homo sapiens_hsa012120.12549375
142Adherens junction_Homo sapiens_hsa045200.09936370
143Butanoate metabolism_Homo sapiens_hsa006500.09792860
144Peroxisome_Homo sapiens_hsa041460.08878658
145Maturity onset diabetes of the young_Homo sapiens_hsa049500.08673740
146HTLV-I infection_Homo sapiens_hsa051660.06981843
147Central carbon metabolism in cancer_Homo sapiens_hsa052300.06738215
148Prostate cancer_Homo sapiens_hsa052150.04226703
149Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.03762817
150Phototransduction_Homo sapiens_hsa047440.02829546

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