N4BP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1transcription from mitochondrial promoter (GO:0006390)8.33895805
2proline metabolic process (GO:0006560)8.01945352
3embryonic process involved in female pregnancy (GO:0060136)7.70256156
4replication fork processing (GO:0031297)7.22266310
5positive regulation of protein homooligomerization (GO:0032464)6.69891234
6establishment of apical/basal cell polarity (GO:0035089)6.64276283
7regulation of integrin activation (GO:0033623)6.37359025
8DNA deamination (GO:0045006)6.21272204
9maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)6.00774794
10regulation of protein homooligomerization (GO:0032462)5.75609829
11establishment of monopolar cell polarity (GO:0061162)5.72419071
12establishment or maintenance of monopolar cell polarity (GO:0061339)5.72419071
13oxidative demethylation (GO:0070989)5.71583599
14somatic hypermutation of immunoglobulin genes (GO:0016446)5.47982336
15somatic diversification of immune receptors via somatic mutation (GO:0002566)5.47982336
16mitochondrial DNA metabolic process (GO:0032042)5.40587745
17DNA strand renaturation (GO:0000733)5.10137173
18mitotic G1 DNA damage checkpoint (GO:0031571)5.06664095
19poly(A)+ mRNA export from nucleus (GO:0016973)4.89518228
20embryonic placenta development (GO:0001892)4.83319555
21regulation of translational fidelity (GO:0006450)4.65805704
22negative regulation of JAK-STAT cascade (GO:0046426)4.62948761
23peptidyl-arginine omega-N-methylation (GO:0035247)4.58348325
24viral mRNA export from host cell nucleus (GO:0046784)4.57112852
25histone arginine methylation (GO:0034969)4.50967978
26mitotic G1/S transition checkpoint (GO:0044819)4.50741489
27L-alpha-amino acid transmembrane transport (GO:1902475)4.49795742
28G1 DNA damage checkpoint (GO:0044783)4.48217976
29pre-miRNA processing (GO:0031054)4.46318329
30regulation of branching involved in prostate gland morphogenesis (GO:0060687)4.36023733
31positive regulation of keratinocyte differentiation (GO:0045618)4.35642640
32negative regulation of cell cycle arrest (GO:0071157)4.31659968
33establishment of protein localization to mitochondrial membrane (GO:0090151)4.29394871
34mRNA cleavage (GO:0006379)4.28113283
35formation of translation preinitiation complex (GO:0001731)4.27350510
36cellular response to ATP (GO:0071318)4.20716696
37glutamine family amino acid biosynthetic process (GO:0009084)4.20614956
38protein complex localization (GO:0031503)4.20395657
39spliceosomal tri-snRNP complex assembly (GO:0000244)4.19824912
40negative regulation of Ras GTPase activity (GO:0034261)4.17022003
41base-excision repair (GO:0006284)4.12796019
42negative regulation of fatty acid biosynthetic process (GO:0045717)4.04634854
43cellular response to zinc ion (GO:0071294)4.00547294
44positive regulation of protein oligomerization (GO:0032461)3.98604767
45adherens junction assembly (GO:0034333)3.97984271
46negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.97410469
47negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.97217284
48histone H4-K12 acetylation (GO:0043983)3.96052024
49DNA unwinding involved in DNA replication (GO:0006268)3.94400953
50DNA integration (GO:0015074)3.93860536
51telomere maintenance via semi-conservative replication (GO:0032201)3.91919731
52ear development (GO:0043583)3.91577081
53positive regulation by host of viral transcription (GO:0043923)3.90007356
54peptidyl-arginine methylation (GO:0018216)3.86901193
55peptidyl-arginine N-methylation (GO:0035246)3.86901193
56apoptotic process involved in morphogenesis (GO:0060561)3.86418981
57negative regulation of protein oligomerization (GO:0032460)3.84744881
58cell-substrate adherens junction assembly (GO:0007045)3.84334817
59focal adhesion assembly (GO:0048041)3.84334817
60positive regulation of developmental pigmentation (GO:0048087)3.82336579
61regulation of gene silencing by RNA (GO:0060966)3.81142946
62regulation of posttranscriptional gene silencing (GO:0060147)3.81142946
63regulation of gene silencing by miRNA (GO:0060964)3.81142946
64trophectodermal cell differentiation (GO:0001829)3.80071925
65embryonic camera-type eye development (GO:0031076)3.77140815
66dosage compensation (GO:0007549)3.76696350
67regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.72397184
68face development (GO:0060324)3.70980596
69regulation of protein oligomerization (GO:0032459)3.70619823
70negative regulation of cell fate specification (GO:0009996)3.69266436
71mitochondrial RNA metabolic process (GO:0000959)3.68117843
72nucleotide-excision repair, DNA gap filling (GO:0006297)3.67819623
73nucleosome disassembly (GO:0006337)3.67337011
74protein-DNA complex disassembly (GO:0032986)3.67337011
75non-recombinational repair (GO:0000726)3.66504792
76double-strand break repair via nonhomologous end joining (GO:0006303)3.66504792
77convergent extension (GO:0060026)3.63593434
78branching involved in salivary gland morphogenesis (GO:0060445)3.62434339
79regulation of mammary gland epithelial cell proliferation (GO:0033599)3.61314704
80regulation of sister chromatid cohesion (GO:0007063)3.60726536
81negative regulation of mRNA processing (GO:0050686)3.54359756
82positive regulation of mitotic sister chromatid separation (GO:1901970)3.53552640
83positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.53552640
84positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.53552640
85nodal signaling pathway (GO:0038092)3.51575341
86heterochromatin organization (GO:0070828)3.49195621
87labyrinthine layer development (GO:0060711)3.48250687
88anatomical structure regression (GO:0060033)3.47518535
89base-excision repair, AP site formation (GO:0006285)3.42691721
90planar cell polarity pathway involved in neural tube closure (GO:0090179)3.41381266
91regulation of RNA export from nucleus (GO:0046831)3.39138473
92glial cell migration (GO:0008347)3.38967680
93positive regulation of Cdc42 GTPase activity (GO:0043089)3.38098102
94cellular protein complex localization (GO:0034629)3.37477488
95DNA topological change (GO:0006265)3.37226882
96termination of RNA polymerase II transcription (GO:0006369)3.33753317
97maternal placenta development (GO:0001893)3.32592029
98endothelium development (GO:0003158)3.31435845
99positive regulation of catenin import into nucleus (GO:0035413)3.29731998
100DNA double-strand break processing (GO:0000729)3.29618164
101regulation of double-strand break repair via homologous recombination (GO:0010569)3.28937844
102nuclear pore complex assembly (GO:0051292)3.28025160
103DNA ligation (GO:0006266)3.26970078
104pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.25759741
105regulation of cell fate specification (GO:0042659)3.24252318
106regulation of histone H3-K27 methylation (GO:0061085)3.23575768
107regulation of chromatin binding (GO:0035561)3.21829403
108semaphorin-plexin signaling pathway (GO:0071526)3.21590723
109determination of adult lifespan (GO:0008340)3.19744003
110meiotic chromosome segregation (GO:0045132)3.18780156
111regulation of hippo signaling (GO:0035330)3.15955506
112positive regulation of SMAD protein import into nucleus (GO:0060391)3.15244232
113paraxial mesoderm development (GO:0048339)3.15124093
114regulation of double-strand break repair (GO:2000779)3.15079387
115positive regulation of DNA repair (GO:0045739)3.14494030
116nuclear envelope reassembly (GO:0031468)3.13933995
117mitotic nuclear envelope reassembly (GO:0007084)3.13933995
118negative regulation of cell fate commitment (GO:0010454)3.13787670
119activation of Rac GTPase activity (GO:0032863)3.13514520
120L-serine metabolic process (GO:0006563)3.13482030
121DNA strand elongation involved in DNA replication (GO:0006271)3.12336836
122post-embryonic morphogenesis (GO:0009886)3.10666279
123negative regulation of histone methylation (GO:0031061)3.09786767
124regulation of cell proliferation involved in kidney development (GO:1901722)3.08690938
125vagina development (GO:0060068)3.08366811
126negative regulation of RNA splicing (GO:0033119)3.08324037
127telomere maintenance via recombination (GO:0000722)3.06191253
128regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.06178124
129GDP-mannose metabolic process (GO:0019673)3.06102384
130maturation of 5.8S rRNA (GO:0000460)3.04858357
131regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)3.04131470
132intracellular estrogen receptor signaling pathway (GO:0030520)3.03986540
133regulation of DNA damage checkpoint (GO:2000001)3.03971992
134positive regulation of epidermal cell differentiation (GO:0045606)3.02433189
135hypotonic response (GO:0006971)3.02204900
136establishment of integrated proviral latency (GO:0075713)3.01630351
137positive regulation of receptor recycling (GO:0001921)3.01215251
138dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.00114034
139epithelial cell differentiation involved in prostate gland development (GO:0060742)2.99263976
140DNA demethylation (GO:0080111)2.98529807
141regulation of cell size (GO:0008361)2.97545310
142regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901212.97381943
143signal complex assembly (GO:0007172)2.96835998
144regulation of podosome assembly (GO:0071801)2.94033818
145cell migration in hindbrain (GO:0021535)2.93435129
146negative regulation of tumor necrosis factor production (GO:0032720)2.93022450
147epithelial cell-cell adhesion (GO:0090136)2.92401203
148DNA strand elongation (GO:0022616)2.91058433
149regulation of histone H3-K9 methylation (GO:0051570)2.88825538
150regulation of establishment or maintenance of cell polarity (GO:0032878)2.88401444
151histone H3-K36 demethylation (GO:0070544)2.84806705
152negative regulation of cell size (GO:0045792)2.81825728
153RNA stabilization (GO:0043489)2.81204481
154mRNA stabilization (GO:0048255)2.81204481
155striated muscle atrophy (GO:0014891)2.80705680
156negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)2.80160103
157regulation of NFAT protein import into nucleus (GO:0051532)2.78107339
158mRNA transcription from RNA polymerase II promoter (GO:0042789)2.77886231
159mitotic chromosome condensation (GO:0007076)2.77605641
160embryonic eye morphogenesis (GO:0048048)2.77285400
161regulation of centriole replication (GO:0046599)2.77167556
162negative regulation of adherens junction organization (GO:1903392)2.75850019
163negative regulation of focal adhesion assembly (GO:0051895)2.75850019
164negative regulation of cell junction assembly (GO:1901889)2.75850019
165pentose-phosphate shunt (GO:0006098)2.73830730
166DNA duplex unwinding (GO:0032508)2.73082212
167protein localization to chromosome, centromeric region (GO:0071459)2.67518281
168protein localization to kinetochore (GO:0034501)2.65612604
169positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.64503079
170regulation of stem cell maintenance (GO:2000036)2.64490974
1713-UTR-mediated mRNA stabilization (GO:0070935)2.64382236
172negative regulation of gene silencing (GO:0060969)2.62889284
173cell differentiation involved in embryonic placenta development (GO:0060706)2.62758862
174peptidyl-tyrosine autophosphorylation (GO:0038083)2.62684538
175embryonic camera-type eye morphogenesis (GO:0048596)2.62179113
176nuclear pore organization (GO:0006999)2.61132842
177positive regulation of cell cycle G2/M phase transition (GO:1902751)2.59978598
178positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.59978598
179regulation of establishment of cell polarity (GO:2000114)2.57333532
180NADPH regeneration (GO:0006740)2.56153030
181cell surface receptor signaling pathway involved in heart development (GO:0061311)2.55036427
182DNA geometric change (GO:0032392)2.53954151
183regulation of glucose import in response to insulin stimulus (GO:2001273)2.53554770
184regulation of nucleobase-containing compound transport (GO:0032239)2.53144268
185proline biosynthetic process (GO:0006561)10.6872076

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SMAD1_18555785_ChIP-Seq_MESCs_Mouse3.55766059
2KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.46608299
3KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.46608299
4KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.46608299
5ZFP281_18358816_ChIP-ChIP_MESCs_Mouse3.26955582
6SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.72656444
7RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.70812316
8MYC_18555785_ChIP-Seq_MESCs_Mouse2.54169435
9NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.53997270
10VDR_21846776_ChIP-Seq_THP-1_Human2.52030155
11SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.48445517
12E2F7_22180533_ChIP-Seq_HELA_Human2.47473015
13NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.44797589
14* ESR2_21235772_ChIP-Seq_MCF-7_Human2.36864109
15KLF4_18358816_ChIP-ChIP_MESCs_Mouse2.30288018
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.29200207
17STAT6_21828071_ChIP-Seq_BEAS2B_Human2.22037746
18MYC_19079543_ChIP-ChIP_MESCs_Mouse2.19297025
19POU5F1_16518401_ChIP-PET_MESCs_Mouse2.14612221
20DACH1_20351289_ChIP-Seq_MDA-MB-231_Human2.14154695
21POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.11680072
22TCF3_18692474_ChIP-Seq_MESCs_Mouse2.09995892
23TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.09147851
24* ESR1_21235772_ChIP-Seq_MCF-7_Human2.08558585
25EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.07803251
26LXR_22292898_ChIP-Seq_THP-1_Human2.06133815
27STAT3_1855785_ChIP-Seq_MESCs_Mouse1.99625864
28NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.96543263
29TCF3_18692474_ChIP-Seq_MEFs_Mouse1.94065845
30* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.93397127
31SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.90326361
32ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.87958257
33MYC_22102868_ChIP-Seq_BL_Human1.86469339
34MYC_18358816_ChIP-ChIP_MESCs_Mouse1.82065270
35FOXM1_23109430_ChIP-Seq_U2OS_Human1.80263033
36CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.76605263
37ERG_21242973_ChIP-ChIP_JURKAT_Human1.74100402
38ZNF263_19887448_ChIP-Seq_K562_Human1.70470915
39NANOG_21062744_ChIP-ChIP_HESCs_Human1.68724212
40CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.68285308
41EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.66404028
42PU.1_20513432_ChIP-Seq_Bcells_Mouse1.63900161
43* RUNX1_27514584_Chip-Seq_MCF-7_Human1.63138713
44NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.61334473
45NANOG_18555785_ChIP-Seq_MESCs_Mouse1.60045926
46MYC_19030024_ChIP-ChIP_MESCs_Mouse1.59815522
47TP63_17297297_ChIP-ChIP_HaCaT_Human1.56952511
48XRN2_22483619_ChIP-Seq_HELA_Human1.56239413
49ZFP281_18757296_ChIP-ChIP_E14_Mouse1.52414088
50KDM2B_26808549_Chip-Seq_K562_Human1.52299098
51ZFP281_27345836_Chip-Seq_ESCs_Mouse1.50102123
52ZFX_18555785_ChIP-Seq_MESCs_Mouse1.49909934
53TET1_21451524_ChIP-Seq_MESCs_Mouse1.47695320
54KLF4_18555785_ChIP-Seq_MESCs_Mouse1.46873433
55* RACK7_27058665_Chip-Seq_MCF-7_Human1.46317803
56CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.43858548
57MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.43597642
58* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.42418762
59NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.40474738
60ESR1_15608294_ChIP-ChIP_MCF-7_Human1.40393553
61POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.40039981
62TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.36454952
63POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.35729063
64* KDM2B_26808549_Chip-Seq_DND41_Human1.35326012
65E2F1_21310950_ChIP-Seq_MCF-7_Human1.35045051
66* HIF1A_21447827_ChIP-Seq_MCF-7_Human1.34258279
67ELK3_25401928_ChIP-Seq_HUVEC_Human1.34203385
68KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.34105156
69ESR1_20079471_ChIP-ChIP_T-47D_Human1.33693924
70KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.33443128
71FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.32364870
72NANOG_18692474_ChIP-Seq_MESCs_Mouse1.30405643
73SOX2_18692474_ChIP-Seq_MESCs_Mouse1.30324689
74SOX2_18692474_ChIP-Seq_MEFs_Mouse1.29139266
75SOX2_18555785_ChIP-Seq_MESCs_Mouse1.27736173
76NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.27050991
77PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.26463797
78KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.25844901
79KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.25534905
80RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.24749836
81CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.23779083
82E2F1_18555785_ChIP-Seq_MESCs_Mouse1.23090975
83PKCTHETA_26484144_Chip-Seq_BREAST_Human1.22788712
84DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.22738730
85WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.22552427
86EGR1_19374776_ChIP-ChIP_THP-1_Human1.21853944
87POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.21608856
88OCT4_18692474_ChIP-Seq_MEFs_Mouse1.21301663
89CREB1_26743006_Chip-Seq_LNCaP_Human1.20685498
90PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.20081693
91P68_20966046_ChIP-Seq_HELA_Human1.19487292
92RARG_19884340_ChIP-ChIP_MEFs_Mouse1.16853254
93BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.16639981
94YY1_21170310_ChIP-Seq_MESCs_Mouse1.16413129
95RXRA_24833708_ChIP-Seq_LIVER_Mouse1.15609032
96ETS1_21867929_ChIP-Seq_TH2_Mouse1.14401944
97SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13594171
98* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.13532841
99MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13383947
100SMC4_20622854_ChIP-Seq_HELA_Human1.13280429
101CTCF_21964334_ChIP-Seq_BJAB-B_Human1.12819235
102SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.12175699
103STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.11577956
104THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.11044408
105CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.10927782
106NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.10327152
107RARB_24833708_ChIP-Seq_LIVER_Mouse1.10211783
108ATF3_27146783_Chip-Seq_COLON_Human1.08030442
109THAP11_20581084_ChIP-Seq_MESCs_Mouse1.07897388
110TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.07568056
111SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.06431034
112NANOG_18692474_ChIP-Seq_MEFs_Mouse1.06031676
113E2F4_17652178_ChIP-ChIP_JURKAT_Human1.05952782
114CLOCK_20551151_ChIP-Seq_293T_Human1.05165367
115TCF7_22412390_ChIP-Seq_EML_Mouse1.05046803
116CTCF_27219007_Chip-Seq_ERYTHROID_Human1.04570443
117SRY_22984422_ChIP-ChIP_TESTIS_Rat1.04501707
118JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.03335352
119TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.02512923
120NELFA_20434984_ChIP-Seq_ESCs_Mouse1.01628224
121PHF8_20622854_ChIP-Seq_HELA_Human1.01090378
122EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.00922751
123BCOR_27268052_Chip-Seq_Bcells_Human1.00047327
124CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99861242
125KAP1_27257070_Chip-Seq_ESCs_Mouse0.99655111
126NCOR1_26117541_ChIP-Seq_K562_Human0.99646857
127MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.99390842
128KDM5A_27292631_Chip-Seq_BREAST_Human0.99066979
129TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.98722851
130UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.97909476
131SPI1_26923725_Chip-Seq_HPCs_Mouse0.97681376
132P300_27058665_Chip-Seq_ZR-75-30cells_Human0.97628987
133KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.96668037
134NANOG_16518401_ChIP-PET_MESCs_Mouse0.96462352
135RARA_24833708_ChIP-Seq_LIVER_Mouse0.96417788

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication6.17323405
2MP0009278_abnormal_bone_marrow4.75459964
3MP0002254_reproductive_system_inflammat4.31856613
4MP0005171_absent_coat_pigmentation4.26621329
5MP0010030_abnormal_orbit_morphology3.56820428
6MP0002009_preneoplasia3.18346362
7MP0004233_abnormal_muscle_weight3.17616285
8MP0010234_abnormal_vibrissa_follicle2.99293393
9MP0009672_abnormal_birth_weight2.85524104
10MP0008995_early_reproductive_senescence2.66572489
11MP0010094_abnormal_chromosome_stability2.41931617
12MP0003283_abnormal_digestive_organ2.41530349
13MP0001849_ear_inflammation2.34843011
14MP0001545_abnormal_hematopoietic_system2.32238778
15MP0005397_hematopoietic_system_phenotyp2.32238778
16MP0003123_paternal_imprinting2.29644236
17MP0003890_abnormal_embryonic-extraembry2.26203113
18MP0004133_heterotaxia2.22734551
19MP0002653_abnormal_ependyma_morphology2.11685304
20MP0003119_abnormal_digestive_system2.10820649
21MP0003453_abnormal_keratinocyte_physiol2.08405819
22MP0005076_abnormal_cell_differentiation1.98224410
23MP0004957_abnormal_blastocyst_morpholog1.98145092
24MP0003786_premature_aging1.97806351
25MP0000537_abnormal_urethra_morphology1.94587936
26MP0010352_gastrointestinal_tract_polyps1.89841980
27MP0002089_abnormal_postnatal_growth/wei1.88989037
28MP0002249_abnormal_larynx_morphology1.86755705
29MP0005174_abnormal_tail_pigmentation1.84833022
30MP0006072_abnormal_retinal_apoptosis1.79118374
31MP0002086_abnormal_extraembryonic_tissu1.78138512
32MP0002796_impaired_skin_barrier1.71755999
33MP0002282_abnormal_trachea_morphology1.71727483
34MP0005451_abnormal_body_composition1.65972133
35MP0004381_abnormal_hair_follicle1.65697437
36MP0002084_abnormal_developmental_patter1.65478732
37MP0003567_abnormal_fetal_cardiomyocyte1.64379876
38MP0000579_abnormal_nail_morphology1.58648558
39MP0004197_abnormal_fetal_growth/weight/1.58549241
40MP0001697_abnormal_embryo_size1.57870152
41MP0010368_abnormal_lymphatic_system1.55140762
42MP0001293_anophthalmia1.54126920
43MP0003111_abnormal_nucleus_morphology1.53500654
44MP0000750_abnormal_muscle_regeneration1.53055468
45MP0004272_abnormal_basement_membrane1.51343501
46MP0002085_abnormal_embryonic_tissue1.49749243
47MP0008058_abnormal_DNA_repair1.47838003
48MP0002098_abnormal_vibrissa_morphology1.47262977
49MP0005409_darkened_coat_color1.44963154
50MP0000490_abnormal_crypts_of1.43230630
51MP0003828_pulmonary_edema1.43030450
52MP0008877_abnormal_DNA_methylation1.42046299
53MP0009703_decreased_birth_body1.40572633
54MP0000377_abnormal_hair_follicle1.39153665
55MP0002697_abnormal_eye_size1.38028650
56MP0001672_abnormal_embryogenesis/_devel1.35159502
57MP0005380_embryogenesis_phenotype1.35159502
58MP0008932_abnormal_embryonic_tissue1.33379882
59MP0000371_diluted_coat_color1.32629826
60MP0000470_abnormal_stomach_morphology1.30468258
61MP0000383_abnormal_hair_follicle1.27949202
62MP0005075_abnormal_melanosome_morpholog1.26954082
63MP0003077_abnormal_cell_cycle1.25209953
64MP0004264_abnormal_extraembryonic_tissu1.24529359
65MP0010678_abnormal_skin_adnexa1.24052592
66MP0005501_abnormal_skin_physiology1.22273164
67MP0002269_muscular_atrophy1.21336370
68MP0003172_abnormal_lysosome_physiology1.20972115
69MP0000350_abnormal_cell_proliferation1.19080875
70MP0004782_abnormal_surfactant_physiolog1.17696404
71MP0002111_abnormal_tail_morphology1.15427641
72MP0000462_abnormal_digestive_system1.14609436
73MP0003878_abnormal_ear_physiology1.14283791
74MP0005377_hearing/vestibular/ear_phenot1.14283791
75MP0000015_abnormal_ear_pigmentation1.14231606
76MP0001730_embryonic_growth_arrest1.12869588
77MP0000678_abnormal_parathyroid_gland1.12168160
78MP0001340_abnormal_eyelid_morphology1.10997104
79MP0000003_abnormal_adipose_tissue1.10031700
80MP0000762_abnormal_tongue_morphology1.09366610
81MP0003984_embryonic_growth_retardation1.07501105
82MP0003942_abnormal_urinary_system1.06871328
83MP0005423_abnormal_somatic_nervous1.06706698
84MP0000639_abnormal_adrenal_gland1.05449790
85MP0000566_synostosis1.03826615
86MP0002088_abnormal_embryonic_growth/wei1.03368941
87MP0002080_prenatal_lethality1.02783327
88MP0002019_abnormal_tumor_incidence1.02747039
89MP0004858_abnormal_nervous_system1.02124389
90MP0001348_abnormal_lacrimal_gland1.01116730
91MP0003705_abnormal_hypodermis_morpholog0.98691759
92MP0002932_abnormal_joint_morphology0.97913694
93MP0003941_abnormal_skin_development0.96860407
94MP0003693_abnormal_embryo_hatching0.96299580
95MP0008260_abnormal_autophagy0.95723471
96MP0002060_abnormal_skin_morphology0.95603436
97MP0003566_abnormal_cell_adhesion0.94451635
98MP0001879_abnormal_lymphatic_vessel0.93917987
99MP0003045_fibrosis0.93660308
100MP0002332_abnormal_exercise_endurance0.93159861
101MP0005266_abnormal_metabolism0.92418684
102MP0003935_abnormal_craniofacial_develop0.91320966
103MP0000685_abnormal_immune_system0.90318208
104MP0000467_abnormal_esophagus_morphology0.89634787
105MP0003115_abnormal_respiratory_system0.89341096
106MP0010630_abnormal_cardiac_muscle0.88332196
107MP0004087_abnormal_muscle_fiber0.86270720
108MP0002075_abnormal_coat/hair_pigmentati0.86008183
109MP0000627_abnormal_mammary_gland0.85674912
110MP0005058_abnormal_lysosome_morphology0.85579321
111MP0009115_abnormal_fat_cell0.84416184
112MP0000428_abnormal_craniofacial_morphol0.83776441
113MP0009053_abnormal_anal_canal0.83235064
114MP0009931_abnormal_skin_appearance0.83097300
115MP0005375_adipose_tissue_phenotype0.82853685
116MP0003861_abnormal_nervous_system0.81906473
117MP0003755_abnormal_palate_morphology0.81868678
118MP0005621_abnormal_cell_physiology0.81208999
119MP0001216_abnormal_epidermal_layer0.81088586
120MP0002092_abnormal_eye_morphology0.80912143
121MP0002114_abnormal_axial_skeleton0.80791591
122MP0005330_cardiomyopathy0.80608542
123MP0000747_muscle_weakness0.79735910
124MP0010307_abnormal_tumor_latency0.79373994
125MP0003137_abnormal_impulse_conducting0.78931453
126MP0005023_abnormal_wound_healing0.78658195
127MP0001346_abnormal_lacrimal_gland0.78592168
128MP0000751_myopathy0.78249516
129MP0001727_abnormal_embryo_implantation0.77745542
130MP0005367_renal/urinary_system_phenotyp0.76702677
131MP0000516_abnormal_urinary_system0.76702677
132MP0004808_abnormal_hematopoietic_stem0.75262390
133MP0002877_abnormal_melanocyte_morpholog0.74904743
134MP0001784_abnormal_fluid_regulation0.74700733
135MP0010771_integument_phenotype0.73720378
136MP0005083_abnormal_biliary_tract0.73061002
137MP0003937_abnormal_limbs/digits/tail_de0.72991773
138MP0000767_abnormal_smooth_muscle0.72547655
139MP0000313_abnormal_cell_death0.71338824
140MP0003718_maternal_effect0.71075869
141MP0000432_abnormal_head_morphology0.70757355
142MP0002405_respiratory_system_inflammati0.69756919
143MP0005384_cellular_phenotype0.69724044
144MP0002116_abnormal_craniofacial_bone0.69155489
145MP0005085_abnormal_gallbladder_physiolo0.68514270
146MP0001186_pigmentation_phenotype0.67310949
147MP0002396_abnormal_hematopoietic_system0.67097122
148MP0002925_abnormal_cardiovascular_devel0.65302301
149MP0000477_abnormal_intestine_morphology0.65143613
150MP0002166_altered_tumor_susceptibility0.63697268
151MP0005508_abnormal_skeleton_morphology0.62243378
152MP0003385_abnormal_body_wall0.61806760
153MP0004185_abnormal_adipocyte_glucose0.61805396

Predicted human phenotypes

RankGene SetZ-score
1Rib fusion (HP:0000902)5.63950512
2Concave nail (HP:0001598)5.33194703
3Annular pancreas (HP:0001734)5.21659946
4Pustule (HP:0200039)4.94963311
5Rectal fistula (HP:0100590)4.84007699
6Rectovaginal fistula (HP:0000143)4.84007699
7Facial hemangioma (HP:0000329)4.83285773
8Increased IgM level (HP:0003496)4.52980671
9Alopecia of scalp (HP:0002293)4.50028358
10Intestinal fistula (HP:0100819)4.38821694
11Poikiloderma (HP:0001029)4.36751814
12Ulnar bowing (HP:0003031)4.36364981
13Turricephaly (HP:0000262)4.35004665
14Vaginal fistula (HP:0004320)4.30524288
15Hypochromic microcytic anemia (HP:0004840)4.06838989
16Hyperacusis (HP:0010780)4.03393887
17Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.98184647
18Short humerus (HP:0005792)3.89012932
19Abnormal hemoglobin (HP:0011902)3.84581524
20Tongue fasciculations (HP:0001308)3.81900290
21Aplasia/hypoplasia of the humerus (HP:0006507)3.76890523
22Intestinal atresia (HP:0011100)3.66548620
23Muscle fibrillation (HP:0010546)3.66081890
24Coronal craniosynostosis (HP:0004440)3.59886214
25Male infertility (HP:0003251)3.51265430
26Orthostatic hypotension (HP:0001278)3.47009910
27Hypotrichosis (HP:0001006)3.42505647
28Asymmetry of the thorax (HP:0001555)3.37153004
29Vertebral hypoplasia (HP:0008417)3.34349689
30Aplasia/Hypoplasia of the vertebrae (HP:0008515)3.34349689
31Absent radius (HP:0003974)3.29725516
32Esophageal varix (HP:0002040)3.25873586
33Basal cell carcinoma (HP:0002671)3.17928323
34J-shaped sella turcica (HP:0002680)3.13345807
35Congenital hip dislocation (HP:0001374)3.11798129
36Squamous cell carcinoma (HP:0002860)3.11588189
37Aplasia involving forearm bones (HP:0009822)3.09668355
38Absent forearm bone (HP:0003953)3.09668355
39Anteriorly placed anus (HP:0001545)3.07780597
40Abnormality of male internal genitalia (HP:0000022)3.03463436
41Micronodular cirrhosis (HP:0001413)3.02568145
42Septate vagina (HP:0001153)3.01562520
43Short chin (HP:0000331)2.99397881
44Premature skin wrinkling (HP:0100678)2.99228483
45Absent thumb (HP:0009777)2.96133728
46Broad alveolar ridges (HP:0000187)2.92853355
47Progressive muscle weakness (HP:0003323)2.90079908
48Overriding aorta (HP:0002623)2.88522126
49Large for gestational age (HP:0001520)2.87137030
50Lymphangioma (HP:0100764)2.87038611
51Alacrima (HP:0000522)2.86566095
52Skull defect (HP:0001362)2.83467119
53Hamartoma (HP:0010566)2.82880337
54Abnormality of the aortic arch (HP:0012303)2.81418611
55Urinary glycosaminoglycan excretion (HP:0003541)2.78868998
56Mucopolysacchariduria (HP:0008155)2.78868998
57Polycythemia (HP:0001901)2.77345595
58Distal lower limb muscle weakness (HP:0009053)2.77117012
59Pancreatic islet-cell hyperplasia (HP:0004510)2.76604442
60Albinism (HP:0001022)2.76081426
61Dysautonomia (HP:0002459)2.74017237
62Selective tooth agenesis (HP:0001592)2.69706099
63Cerebral aneurysm (HP:0004944)2.66678223
64Growth hormone excess (HP:0000845)2.65390995
65Volvulus (HP:0002580)2.62756004
66Diaphragmatic weakness (HP:0009113)2.61763155
67Patellar aplasia (HP:0006443)2.54774090
68Hypochromic anemia (HP:0001931)2.53155505
69Capillary hemangiomas (HP:0005306)2.50801236
70Chromosomal breakage induced by crosslinking agents (HP:0003221)2.48670205
71Hypotelorism (HP:0000601)2.48234906
72Nephroblastoma (Wilms tumor) (HP:0002667)2.48112586
73Elfin facies (HP:0004428)2.48111672
74Long palpebral fissure (HP:0000637)2.48015696
75Bowed forearm bones (HP:0003956)2.46373270
76Bowing of the arm (HP:0006488)2.46373270
77Abnormality of mucopolysaccharide metabolism (HP:0011020)2.46043726
78Abnormality of polysaccharide metabolism (HP:0011012)2.46043726
79Abnormality of glycosaminoglycan metabolism (HP:0004371)2.46043726
80Joint stiffness (HP:0001387)2.45478217
81Choanal stenosis (HP:0000452)2.44403889
82Dysmetric saccades (HP:0000641)2.43398132
83Vertebral fusion (HP:0002948)2.43037138
84Bifid uvula (HP:0000193)2.40844568
85Trismus (HP:0000211)2.40475381
86Germ cell neoplasia (HP:0100728)2.39496477
87Dysostosis multiplex (HP:0000943)2.37066050
88Astrocytoma (HP:0009592)2.36909918
89Abnormality of the astrocytes (HP:0100707)2.36909918
90Gastrointestinal atresia (HP:0002589)2.35470174
91IgA deficiency (HP:0002720)2.35438231
92Uterine leiomyosarcoma (HP:0002891)2.34725011
93Leiomyosarcoma (HP:0100243)2.34725011
94Malignant gastrointestinal tract tumors (HP:0006749)2.32520560
95Gastrointestinal carcinoma (HP:0002672)2.32520560
96Abnormality of the salivary glands (HP:0010286)2.31793809
97Aplasia/Hypoplasia of the patella (HP:0006498)2.31197369
98Insomnia (HP:0100785)2.30926892
99Clumsiness (HP:0002312)2.30707450
100Premature graying of hair (HP:0002216)2.30017869
101Aplasia of the musculature (HP:0100854)2.29714188
102Abnormality of cochlea (HP:0000375)2.26696275
103Progressive external ophthalmoplegia (HP:0000590)2.24950679
104Embryonal renal neoplasm (HP:0011794)2.24016550
105Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.23843352
106Spastic diplegia (HP:0001264)2.21109445
107Increased nuchal translucency (HP:0010880)2.20806031
108High pitched voice (HP:0001620)2.20041943
109Amelogenesis imperfecta (HP:0000705)2.19922040
110Neoplasm of the oral cavity (HP:0100649)2.19289673
111Abnormality of the labia minora (HP:0012880)2.18871208
112Split hand (HP:0001171)2.18212969
113Bronchomalacia (HP:0002780)2.17527745
114Enlarged penis (HP:0000040)2.16548023
115Pointed chin (HP:0000307)2.15541676
116Acute lymphatic leukemia (HP:0006721)2.14853591
117Generalized hypotonia (HP:0001290)2.14461910
118Bulbar palsy (HP:0001283)2.14207518
119Chromsome breakage (HP:0040012)2.12236760
120Microglossia (HP:0000171)2.12114383
121Hepatoblastoma (HP:0002884)2.10845367
122Hypokinesia (HP:0002375)2.10173418
123Decreased lacrimation (HP:0000633)2.09638037
124Arnold-Chiari malformation (HP:0002308)2.09591673
125Increased number of teeth (HP:0011069)2.07453357
126Popliteal pterygium (HP:0009756)2.04652643
127Centrally nucleated skeletal muscle fibers (HP:0003687)2.03339339
128Redundant skin (HP:0001582)2.03220272
129Breast carcinoma (HP:0003002)2.03009933
130Hypercortisolism (HP:0001578)2.02181592
131Hypoplasia of the radius (HP:0002984)2.01542828
132Asymmetric septal hypertrophy (HP:0001670)2.00405363
133Narrow nasal bridge (HP:0000446)1.99663590
134Broad distal phalanx of finger (HP:0009836)1.99428315
135Spinal muscular atrophy (HP:0007269)1.97996631
136Advanced eruption of teeth (HP:0006288)1.96254663
137Abnormality of the lower motor neuron (HP:0002366)1.96002547
138Hypoplasia of the ulna (HP:0003022)1.95825939
139Sparse lateral eyebrow (HP:0005338)1.94997547
140Generalized amyotrophy (HP:0003700)1.91319432
141Right ventricular cardiomyopathy (HP:0011663)1.87978077
142Spina bifida occulta (HP:0003298)1.86846538
143Abnormal number of incisors (HP:0011064)1.86616194
144Ependymoma (HP:0002888)1.85989734
145Colitis (HP:0002583)1.85953764
146Short 5th finger (HP:0009237)1.85809584
147Hyporeflexia of lower limbs (HP:0002600)1.85768762
148Renovascular hypertension (HP:0100817)1.83293303
149Curly hair (HP:0002212)1.83016968
150Thin ribs (HP:0000883)1.82434372
151Transitional cell carcinoma of the bladder (HP:0006740)1.81499093
152Absent eyelashes (HP:0000561)1.80820837
153Deformed sella turcica (HP:0002681)1.79386302
154High anterior hairline (HP:0009890)1.77926738
155Hemangiomatosis (HP:0007461)1.77330559
156Pterygium (HP:0001059)1.76821970
157Multiple enchondromatosis (HP:0005701)1.76260393
158Aplasia involving bones of the extremities (HP:0009825)1.73046381
159Aplasia involving bones of the upper limbs (HP:0009823)1.73046381
160Aplasia of the phalanges of the hand (HP:0009802)1.73046381
161Anal stenosis (HP:0002025)1.72771085
162Hypoparathyroidism (HP:0000829)1.72372322
163Precocious puberty (HP:0000826)1.72242522
164Distal lower limb amyotrophy (HP:0008944)1.72092102
165Lower limb amyotrophy (HP:0007210)1.72086308
166Patellar dislocation (HP:0002999)1.71861835
167Abnormality of the fingertips (HP:0001211)1.70104622
168Renal duplication (HP:0000075)1.70062560
169Tracheal stenosis (HP:0002777)1.69318492
170Deep philtrum (HP:0002002)1.69283135
171Reticulocytopenia (HP:0001896)1.68354722
172Shallow orbits (HP:0000586)1.67300648
173Abnormality of the distal phalanx of the thumb (HP:0009617)1.65996143
174Visceral angiomatosis (HP:0100761)1.65465162
175Increased connective tissue (HP:0009025)1.65193694
176Abnormality of reticulocytes (HP:0004312)1.64904619
177Abnormality of the septum pellucidum (HP:0007375)1.64862635
178Renal cell carcinoma (HP:0005584)1.64248290
179Reticulocytosis (HP:0001923)1.63270360
180Atresia of the external auditory canal (HP:0000413)1.63266790
181Neoplasm of the adrenal cortex (HP:0100641)1.63138178
182Difficulty climbing stairs (HP:0003551)1.62180634
183Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.61784635
184Metaphyseal cupping (HP:0003021)1.61762577
185Embryonal neoplasm (HP:0002898)1.60968255
186Areflexia of lower limbs (HP:0002522)1.60378634
187Bladder neoplasm (HP:0009725)1.60196515
188Bladder carcinoma (HP:0002862)1.60196515
189Abnormality of nail color (HP:0100643)1.59001239
190Deviation of the thumb (HP:0009603)1.58692199
191Uterine neoplasm (HP:0010784)1.57122035
192Abnormality of the lacrimal duct (HP:0011481)1.56652284

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ICK6.04618763
2MAPK155.27926861
3DDR24.77882124
4SMG14.70779366
5MAP3K64.48972672
6EEF2K3.90548885
7SIK13.85818415
8MAP3K113.45712678
9TYRO33.06009811
10MATK3.00615384
11PINK12.94513018
12FGR2.89986522
13DAPK12.38053682
14BMX2.34238277
15UHMK12.30612027
16PRKD22.25104889
17CSK2.22904952
18PIM22.16884379
19DYRK1B2.12118681
20YES12.08734588
21PKN22.07687379
22SCYL22.03755155
23PDGFRA2.02041816
24NME21.90736167
25FGFR41.86585574
26VRK21.79775256
27CDK71.78397926
28TAF11.68692845
29MAP2K21.62291758
30CDK61.51359300
31MAP3K101.50458018
32PIM11.47911071
33AKT31.44926914
34MUSK1.37299823
35LATS21.31409462
36TRPM71.30124975
37TTK1.29795360
38RPS6KL11.27091944
39RPS6KC11.27091944
40TTN1.18612786
41TSSK61.18498449
42TESK21.15919720
43NEK61.12324605
44RPS6KA61.09856623
45CDC42BPA1.09452724
46GSK3A1.09239644
47MAPK111.08981965
48BRD41.08104704
49PTK61.04090695
50EPHA21.02582348
51FGFR21.02070303
52CHEK21.01389869
53IRAK31.00562779
54CDK120.99927857
55CHUK0.99549635
56RPS6KA20.99011750
57PHKG10.94461063
58PHKG20.94461063
59NME10.94039955
60DYRK30.93329132
61RPS6KB20.89422819
62SRPK10.82915967
63PLK10.78036901
64HIPK20.77061669
65MTOR0.75214034
66PASK0.69366937
67RPS6KA10.68253592
68ARAF0.67687230
69PIK3CA0.64153780
70PRKAA10.63187287
71BRAF0.62546741
72TRIB30.60787089
73SIK30.57968201
74TAOK20.57652293
75PRKCI0.56927922
76MAPKAPK30.53760888
77PRPF4B0.52983998
78FGFR10.52649653
79MAP3K80.51844775
80RAF10.50234221
81ATR0.50112812
82NEK20.49848376
83BUB10.49816471
84KSR20.49038485
85RIPK10.49010805
86PRKG20.47770574
87CDK20.47095906
88EGFR0.46938429
89MAP2K10.46773594
90EIF2AK20.46548371
91AKT20.44252342
92IRAK20.43452856
93MAP3K90.42674358
94CDK90.42053698
95WEE10.41148715
96DAPK30.40706041
97PBK0.40231433
98CSNK2A10.38240946
99KDR0.38240739
100PDPK10.38080564
101MAP3K10.37502190
102LYN0.37484606
103MAPK10.35709530
104ALK0.35549154
105PDGFRB0.35013362
106TESK10.34947944
107MELK0.34190274
108AURKA0.33483979
109MAPK90.33249670
110MAPK30.32975324
111MAP3K130.32333351
112MAPK40.32104243
113ERN10.31720794
114MAPK80.31482463
115STK100.30958261
116FLT30.30819498
117CDK40.30588120
118CHEK10.29539208
119PAK40.29525418
120RPS6KB10.29505313
121NEK10.29142395
122STK40.28960496
123PTK20.28761452
124PRKAA20.28372358
125GSK3B0.27306634
126STK30.27125240
127CSNK2A20.27109401
128TAOK10.27077266
129RET0.26503708
130MAPK140.26480095
131ATM0.25699717
132TIE10.25589414
133TNK20.24937824
134MAPK100.24612326
135ERBB30.24573577
136MAPKAPK20.23990671
137INSR0.23969926
138TLK10.23627261
139MAP4K10.22801217
140PAK20.22769972
141CDC70.22388652
142DYRK20.22130068
143CAMK2G0.22058535
144CAMK2B0.21349091
145PRKD10.21311400
146AURKB0.20478490
147LATS10.19677706
148CSNK1G10.19522732
149CDK10.18957897
150GRK60.18235459
151SIK20.16520934
152MARK20.16050880
153DMPK0.14170951

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000615.22175636
2Mismatch repair_Homo sapiens_hsa034305.09083362
3Base excision repair_Homo sapiens_hsa034104.71780023
4DNA replication_Homo sapiens_hsa030303.89084719
5Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.54646732
6Nucleotide excision repair_Homo sapiens_hsa034202.24197497
7Notch signaling pathway_Homo sapiens_hsa043302.23202511
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.12923796
9Spliceosome_Homo sapiens_hsa030402.06418025
10Hippo signaling pathway_Homo sapiens_hsa043902.05426858
11Hedgehog signaling pathway_Homo sapiens_hsa043402.02134464
12mTOR signaling pathway_Homo sapiens_hsa041502.01554143
13Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.00638389
14mRNA surveillance pathway_Homo sapiens_hsa030151.97891792
15RNA transport_Homo sapiens_hsa030131.89881226
16Adherens junction_Homo sapiens_hsa045201.85141951
17Arginine and proline metabolism_Homo sapiens_hsa003301.79827862
18Pentose phosphate pathway_Homo sapiens_hsa000301.79329428
19Homologous recombination_Homo sapiens_hsa034401.76816492
20Circadian rhythm_Homo sapiens_hsa047101.74622056
21p53 signaling pathway_Homo sapiens_hsa041151.65320734
222-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.64312054
23Fanconi anemia pathway_Homo sapiens_hsa034601.60721845
24Biosynthesis of amino acids_Homo sapiens_hsa012301.57685169
25Sulfur relay system_Homo sapiens_hsa041221.48100238
26Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.44782686
27Basal cell carcinoma_Homo sapiens_hsa052171.44474277
28Bladder cancer_Homo sapiens_hsa052191.43275268
29Transcriptional misregulation in cancer_Homo sapiens_hsa052021.41662250
30Non-small cell lung cancer_Homo sapiens_hsa052231.40531004
31TGF-beta signaling pathway_Homo sapiens_hsa043501.39515862
32Longevity regulating pathway - mammal_Homo sapiens_hsa042111.31827635
33Cell cycle_Homo sapiens_hsa041101.31514108
34Glioma_Homo sapiens_hsa052141.28432101
35Renal cell carcinoma_Homo sapiens_hsa052111.27206415
36Alcoholism_Homo sapiens_hsa050341.26428179
37Wnt signaling pathway_Homo sapiens_hsa043101.22693779
38Ribosome_Homo sapiens_hsa030101.21938640
39VEGF signaling pathway_Homo sapiens_hsa043701.21215683
40Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.17025217
41Fatty acid metabolism_Homo sapiens_hsa012121.14684239
42Shigellosis_Homo sapiens_hsa051311.13462636
43Folate biosynthesis_Homo sapiens_hsa007901.12914553
44Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.09698644
45Primary immunodeficiency_Homo sapiens_hsa053401.07680185
46Leukocyte transendothelial migration_Homo sapiens_hsa046701.07554389
47Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.07552039
48Lysine degradation_Homo sapiens_hsa003101.07056032
49Neurotrophin signaling pathway_Homo sapiens_hsa047221.06680426
50Systemic lupus erythematosus_Homo sapiens_hsa053221.03208109
51Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.02877937
52Vitamin B6 metabolism_Homo sapiens_hsa007500.97327514
53Hepatitis C_Homo sapiens_hsa051600.94859336
54Fructose and mannose metabolism_Homo sapiens_hsa000510.94408296
55Oocyte meiosis_Homo sapiens_hsa041140.92209256
56Colorectal cancer_Homo sapiens_hsa052100.91910309
57Axon guidance_Homo sapiens_hsa043600.91168405
58Inositol phosphate metabolism_Homo sapiens_hsa005620.89739399
59MicroRNAs in cancer_Homo sapiens_hsa052060.89398188
60Tight junction_Homo sapiens_hsa045300.88529821
61Carbon metabolism_Homo sapiens_hsa012000.86824545
62Melanoma_Homo sapiens_hsa052180.86035512
63Arginine biosynthesis_Homo sapiens_hsa002200.83309649
64Phosphatidylinositol signaling system_Homo sapiens_hsa040700.83172553
65Melanogenesis_Homo sapiens_hsa049160.80445906
66Regulation of actin cytoskeleton_Homo sapiens_hsa048100.78588336
67Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.75348590
68Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.75136046
69Sphingolipid signaling pathway_Homo sapiens_hsa040710.75011820
70Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.73741586
71Pentose and glucuronate interconversions_Homo sapiens_hsa000400.73622839
72Viral myocarditis_Homo sapiens_hsa054160.73005076
73Acute myeloid leukemia_Homo sapiens_hsa052210.71950294
74Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.71837392
75Insulin resistance_Homo sapiens_hsa049310.71458408
76Dorso-ventral axis formation_Homo sapiens_hsa043200.71417059
77Small cell lung cancer_Homo sapiens_hsa052220.71332282
78One carbon pool by folate_Homo sapiens_hsa006700.69528631
79Prolactin signaling pathway_Homo sapiens_hsa049170.69358728
80Chronic myeloid leukemia_Homo sapiens_hsa052200.69000609
81Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.68505047
82Phospholipase D signaling pathway_Homo sapiens_hsa040720.67805681
83Thyroid cancer_Homo sapiens_hsa052160.66416079
84Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.65860734
85Apoptosis_Homo sapiens_hsa042100.65299748
86Glycosaminoglycan degradation_Homo sapiens_hsa005310.63847854
87Viral carcinogenesis_Homo sapiens_hsa052030.63146794
88Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.61730247
89Long-term potentiation_Homo sapiens_hsa047200.60673970
90GnRH signaling pathway_Homo sapiens_hsa049120.59550869
91ErbB signaling pathway_Homo sapiens_hsa040120.57555025
92Gap junction_Homo sapiens_hsa045400.57543813
93Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.56701474
94Choline metabolism in cancer_Homo sapiens_hsa052310.56511963
95AMPK signaling pathway_Homo sapiens_hsa041520.55986130
96Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.55068522
97Non-homologous end-joining_Homo sapiens_hsa034500.54560177
98Glucagon signaling pathway_Homo sapiens_hsa049220.54367334
99Proteoglycans in cancer_Homo sapiens_hsa052050.50902771
100Central carbon metabolism in cancer_Homo sapiens_hsa052300.49277028
101Legionellosis_Homo sapiens_hsa051340.48696516
102Galactose metabolism_Homo sapiens_hsa000520.46875338
103Maturity onset diabetes of the young_Homo sapiens_hsa049500.44412414
104Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.43071354
105Insulin signaling pathway_Homo sapiens_hsa049100.42211365
106HTLV-I infection_Homo sapiens_hsa051660.41593073
107Focal adhesion_Homo sapiens_hsa045100.41070422
108PI3K-Akt signaling pathway_Homo sapiens_hsa041510.39067994
109Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.38222032
110Pathways in cancer_Homo sapiens_hsa052000.38093312
111Herpes simplex infection_Homo sapiens_hsa051680.35979831
112Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.35975261
113B cell receptor signaling pathway_Homo sapiens_hsa046620.34412473
114MAPK signaling pathway_Homo sapiens_hsa040100.33711405
115Glutathione metabolism_Homo sapiens_hsa004800.33486670
116Epstein-Barr virus infection_Homo sapiens_hsa051690.32070612
117Endometrial cancer_Homo sapiens_hsa052130.30598429
118HIF-1 signaling pathway_Homo sapiens_hsa040660.28849243
119RNA degradation_Homo sapiens_hsa030180.27854679
120Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.27030263
121Cyanoamino acid metabolism_Homo sapiens_hsa004600.25535524
122Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.24955603
123Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.24462861
124Rap1 signaling pathway_Homo sapiens_hsa040150.23908984
125Prostate cancer_Homo sapiens_hsa052150.22396928
126Hepatitis B_Homo sapiens_hsa051610.22072811
127Endocytosis_Homo sapiens_hsa041440.20914775
128AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.17278895
129Thyroid hormone signaling pathway_Homo sapiens_hsa049190.17158701
130Pancreatic cancer_Homo sapiens_hsa052120.16475097
131Estrogen signaling pathway_Homo sapiens_hsa049150.14632266
132Basal transcription factors_Homo sapiens_hsa030220.11697143
133Selenocompound metabolism_Homo sapiens_hsa004500.10223494
134Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.10132934

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »