NAA11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1piRNA metabolic process (GO:0034587)7.53745783
2regulation of DNA methylation (GO:0044030)7.13753658
3regulation of retinoic acid receptor signaling pathway (GO:0048385)6.95209756
4synapsis (GO:0007129)6.02134993
5regulation of female gonad development (GO:2000194)6.00616093
6regulation of acrosome reaction (GO:0060046)5.63301591
7mitotic metaphase plate congression (GO:0007080)5.29660152
8positive regulation of histone H3-K4 methylation (GO:0051571)5.18678233
9DNA methylation involved in gamete generation (GO:0043046)5.15744800
10male meiosis (GO:0007140)4.93035128
11synaptonemal complex assembly (GO:0007130)4.90570663
12regulation of histone H3-K9 methylation (GO:0051570)4.79985882
13oocyte development (GO:0048599)4.78398794
14regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.65180917
15synaptonemal complex organization (GO:0070193)4.64847722
16regulation of histone H3-K4 methylation (GO:0051569)4.47355531
17protein localization to kinetochore (GO:0034501)4.38742555
18metaphase plate congression (GO:0051310)4.37776734
19DNA replication-dependent nucleosome assembly (GO:0006335)4.33662101
20DNA replication-dependent nucleosome organization (GO:0034723)4.33662101
21mitotic sister chromatid segregation (GO:0000070)4.23557799
22regulation of meiosis I (GO:0060631)4.17171067
23protein localization to chromosome, centromeric region (GO:0071459)4.14830513
24DNA replication checkpoint (GO:0000076)4.11666030
25attachment of spindle microtubules to kinetochore (GO:0008608)4.10302383
26meiotic nuclear division (GO:0007126)4.10252748
27mitotic chromosome condensation (GO:0007076)4.02411548
28meiotic chromosome segregation (GO:0045132)3.96590771
29regulation of RNA export from nucleus (GO:0046831)3.91999373
30protein K6-linked ubiquitination (GO:0085020)3.91672160
31histone H3-K9 demethylation (GO:0033169)3.88349370
32negative regulation of reproductive process (GO:2000242)3.83458874
33establishment of chromosome localization (GO:0051303)3.80897118
34meiotic cell cycle (GO:0051321)3.78747857
35regulation of spindle organization (GO:0090224)3.78321960
36mitotic nuclear envelope disassembly (GO:0007077)3.77215215
37male meiosis I (GO:0007141)3.75427301
38protein kinase C signaling (GO:0070528)3.74567017
39negative regulation of meiosis (GO:0045835)3.72262068
40regulation of chromosome segregation (GO:0051983)3.71516367
41positive regulation of chromosome segregation (GO:0051984)3.71431699
42binding of sperm to zona pellucida (GO:0007339)3.67484408
43chromosome organization involved in meiosis (GO:0070192)3.66902833
44meiosis I (GO:0007127)3.65510822
45ribosome assembly (GO:0042255)3.64359657
46histone exchange (GO:0043486)3.63387436
47regulation of histone methylation (GO:0031060)3.62557035
48maturation of 5.8S rRNA (GO:0000460)3.58952280
49gene silencing by RNA (GO:0031047)3.58709091
50meiotic cell cycle process (GO:1903046)3.56279030
51gonadal mesoderm development (GO:0007506)3.56113086
52chromatin remodeling at centromere (GO:0031055)3.54575117
53multicellular organism reproduction (GO:0032504)3.54199556
54membrane disassembly (GO:0030397)3.52756438
55nuclear envelope disassembly (GO:0051081)3.52756438
56centriole replication (GO:0007099)3.51947262
57resolution of meiotic recombination intermediates (GO:0000712)3.51364482
58negative regulation of chromosome segregation (GO:0051985)3.50795843
59spindle checkpoint (GO:0031577)3.49608355
60histone H2A monoubiquitination (GO:0035518)3.48633018
61negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.46489391
62female gamete generation (GO:0007292)3.45334042
63proteasome assembly (GO:0043248)3.44858556
64purine nucleobase biosynthetic process (GO:0009113)3.43714958
65sister chromatid segregation (GO:0000819)3.42874956
66protein localization to chromosome (GO:0034502)3.42631868
67positive regulation of histone methylation (GO:0031062)3.42245538
68DNA replication initiation (GO:0006270)3.41987562
69rRNA modification (GO:0000154)3.41704081
70glycine transport (GO:0015816)3.40552545
71negative regulation of sister chromatid segregation (GO:0033046)3.40338295
72negative regulation of mitotic sister chromatid separation (GO:2000816)3.40338295
73negative regulation of mitotic sister chromatid segregation (GO:0033048)3.40338295
74negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.40338295
75CENP-A containing nucleosome assembly (GO:0034080)3.39402141
76sperm-egg recognition (GO:0035036)3.38986286
77mitotic spindle checkpoint (GO:0071174)3.36445166
78oocyte maturation (GO:0001556)3.35122254
79nuclear pore organization (GO:0006999)3.34923424
80regulation of double-strand break repair via homologous recombination (GO:0010569)3.34206331
81DNA replication-independent nucleosome organization (GO:0034724)3.34008801
82DNA replication-independent nucleosome assembly (GO:0006336)3.34008801
83pore complex assembly (GO:0046931)3.33739156
84regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.33278498
85regulation of sister chromatid cohesion (GO:0007063)3.32963665
86regulation of meiosis (GO:0040020)3.32827827
87formation of translation preinitiation complex (GO:0001731)3.32265042
88chromosome segregation (GO:0007059)3.31313594
89DNA strand elongation (GO:0022616)3.29919411
90microtubule depolymerization (GO:0007019)3.29267541
91regulation of centrosome cycle (GO:0046605)3.28884820
92regulation of mitotic metaphase/anaphase transition (GO:0030071)3.28250661
93protein deneddylation (GO:0000338)3.28199812
94DNA strand elongation involved in DNA replication (GO:0006271)3.27225206
95mitotic spindle assembly checkpoint (GO:0007094)3.26298462
96nuclear pore complex assembly (GO:0051292)3.25777918
97nucleobase biosynthetic process (GO:0046112)3.25608037
98spindle assembly checkpoint (GO:0071173)3.23387269
99negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.23288700
100regulation of mitotic spindle organization (GO:0060236)3.22352525
101kinetochore assembly (GO:0051382)3.20305875
102retinal cone cell development (GO:0046549)3.20190422
103telomere maintenance via semi-conservative replication (GO:0032201)3.19047248
104regulation of telomere maintenance via telomerase (GO:0032210)3.18906482
105regulation of mitotic sister chromatid separation (GO:0010965)3.18532644
106regulation of mitotic sister chromatid segregation (GO:0033047)3.18532644
107regulation of sister chromatid segregation (GO:0033045)3.18532644
108phosphorelay signal transduction system (GO:0000160)3.18357469
109reproduction (GO:0000003)3.16767584
110fusion of sperm to egg plasma membrane (GO:0007342)3.16367949
111DNA alkylation (GO:0006305)3.16098494
112DNA methylation (GO:0006306)3.16098494
113regulation of steroid hormone secretion (GO:2000831)3.15821006
114reciprocal DNA recombination (GO:0035825)3.14950059
115reciprocal meiotic recombination (GO:0007131)3.14950059
116kinetochore organization (GO:0051383)3.14477465
117regulation of nucleobase-containing compound transport (GO:0032239)3.14091033
118regulation of spindle checkpoint (GO:0090231)3.11411200
119mitotic G2/M transition checkpoint (GO:0044818)3.11206616
120nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)3.10346577
121anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.08379660
122regulation of histone H3-K27 methylation (GO:0061085)3.07708949
123regulation of exit from mitosis (GO:0007096)3.06138577
124rRNA methylation (GO:0031167)3.05519872
125histone H2A ubiquitination (GO:0033522)3.04833190
126positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.04640390
127positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.04640390
128positive regulation of mitotic sister chromatid separation (GO:1901970)3.04640390
129regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.03163431
130ribosome biogenesis (GO:0042254)3.02966931
131chromosome condensation (GO:0030261)3.01372465
132histone phosphorylation (GO:0016572)3.01089250
133somatic diversification of immune receptors via somatic mutation (GO:0002566)2.99221076
134somatic hypermutation of immunoglobulin genes (GO:0016446)2.99221076
135negative regulation of histone methylation (GO:0031061)2.98357855
136regulation of gene expression by genetic imprinting (GO:0006349)2.95068844
137positive regulation of meiosis (GO:0045836)2.92711506
138fertilization (GO:0009566)2.90105738
139gene silencing (GO:0016458)2.89385873
140chromatin assembly or disassembly (GO:0006333)2.87630038

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.81625237
2EZH2_22144423_ChIP-Seq_EOC_Human6.61689915
3MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.97814333
4FOXM1_23109430_ChIP-Seq_U2OS_Human4.26099476
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.37343699
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.31404073
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.25213986
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.89578599
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.63417447
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.62227182
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.61292484
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.48485434
13NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.47161521
14SALL1_21062744_ChIP-ChIP_HESCs_Human2.46052584
15AR_21909140_ChIP-Seq_LNCAP_Human2.45805899
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.42191408
17ETS1_20019798_ChIP-Seq_JURKAT_Human2.42092709
18NANOG_18555785_ChIP-Seq_MESCs_Mouse2.41516963
19MYC_19030024_ChIP-ChIP_MESCs_Mouse2.40958732
20MYC_18358816_ChIP-ChIP_MESCs_Mouse2.40860504
21GABP_17652178_ChIP-ChIP_JURKAT_Human2.38763775
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.30537317
23KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.29593751
24KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.29593751
25KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.29593751
26MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.25145722
27NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.21818879
28SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.17232599
29KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.10572864
30POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.08579263
31NELFA_20434984_ChIP-Seq_ESCs_Mouse2.07928572
32MYCN_18555785_ChIP-Seq_MESCs_Mouse2.07439495
33POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.06227505
34NOTCH1_21737748_ChIP-Seq_TLL_Human2.05403214
35HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.01640788
36NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.97356329
37MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.95259601
38BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.94955086
39EGR1_19374776_ChIP-ChIP_THP-1_Human1.86727248
40GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.82344770
41EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.80329538
42POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.76597613
43E2F1_18555785_ChIP-Seq_MESCs_Mouse1.75658959
44XRN2_22483619_ChIP-Seq_HELA_Human1.73660459
45VDR_23849224_ChIP-Seq_CD4+_Human1.69272978
46KAP1_22055183_ChIP-Seq_ESCs_Mouse1.67791378
47GABP_19822575_ChIP-Seq_HepG2_Human1.66380937
48YY1_21170310_ChIP-Seq_MESCs_Mouse1.58523352
49E2F1_21310950_ChIP-Seq_MCF-7_Human1.57646094
50STAT3_1855785_ChIP-Seq_MESCs_Mouse1.55799628
51RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.54994690
52HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.51591379
53PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.51197372
54CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.48890738
55DCP1A_22483619_ChIP-Seq_HELA_Human1.48315267
56HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.47573330
57TCF3_18692474_ChIP-Seq_MESCs_Mouse1.47391427
58KLF4_18555785_ChIP-Seq_MESCs_Mouse1.46817918
59ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.44981881
60ELK1_19687146_ChIP-ChIP_HELA_Human1.44845525
61NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.44581815
62TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.44121438
63NANOG_21062744_ChIP-ChIP_HESCs_Human1.43470655
64TTF2_22483619_ChIP-Seq_HELA_Human1.42582385
65GATA1_26923725_Chip-Seq_HPCs_Mouse1.41377070
66TCF3_18692474_ChIP-Seq_MEFs_Mouse1.40403373
67PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.39514299
68HOXB4_20404135_ChIP-ChIP_EML_Mouse1.38983235
69PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.38594159
70SOX2_18555785_ChIP-Seq_MESCs_Mouse1.37630302
71TP63_19390658_ChIP-ChIP_HaCaT_Human1.37480100
72HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.37391312
73FOXP3_21729870_ChIP-Seq_TREG_Human1.35605819
74THAP11_20581084_ChIP-Seq_MESCs_Mouse1.35409614
75KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.33723335
76KDM5A_27292631_Chip-Seq_BREAST_Human1.33382957
77FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.32095753
78NCOR1_26117541_ChIP-Seq_K562_Human1.27895866
79YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.25892453
80SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.23805295
81ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.18139169
82ELF1_17652178_ChIP-ChIP_JURKAT_Human1.16259243
83NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.15782918
84POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.15343556
85ZFX_18555785_ChIP-Seq_MESCs_Mouse1.14688624
86NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.13123138
87VDR_22108803_ChIP-Seq_LS180_Human1.11456057
88DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.11138125
89NANOG_18692474_ChIP-Seq_MEFs_Mouse1.10251402
90ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.10230521
91NANOG_18692474_ChIP-Seq_MESCs_Mouse1.09944964
92KAP1_27257070_Chip-Seq_ESCs_Mouse1.09860998
93SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.07739027
94SRF_21415370_ChIP-Seq_HL-1_Mouse1.05395907
95SOX2_18692474_ChIP-Seq_MESCs_Mouse1.05256273
96CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.04041759
97CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.03874765
98SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.03845914
99SOX2_18692474_ChIP-Seq_MEFs_Mouse1.03814912
100SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.03227985
101POU5F1_16518401_ChIP-PET_MESCs_Mouse1.00671217
102CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.98813256
103E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.98513613
104CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.98408592
105SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.96854041
106TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.96224975
107STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.96196193
108SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.95913475
109MYC_18940864_ChIP-ChIP_HL60_Human0.95682357
110PKCTHETA_26484144_Chip-Seq_BREAST_Human0.92321194
111IRF1_19129219_ChIP-ChIP_H3396_Human0.90901170
112FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.90103086
113CIITA_25753668_ChIP-Seq_RAJI_Human0.90062855
114TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.89956261
115CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.89767552
116PADI4_21655091_ChIP-ChIP_MCF-7_Human0.86993115
117BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.86930353
118KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.86752886
119OCT4_18692474_ChIP-Seq_MEFs_Mouse0.84870338
120ERG_20887958_ChIP-Seq_HPC-7_Mouse0.83273409
121PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.82585467
122LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.81821512
123TFEB_21752829_ChIP-Seq_HELA_Human0.81776241
124RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.81156977
125ESR1_15608294_ChIP-ChIP_MCF-7_Human0.80463484
126RBPJ_21746931_ChIP-Seq_IB4_Human0.79369250
127PHF8_20622853_ChIP-Seq_HELA_Human0.78937116
128PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.78918120
129SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.78408740
130CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.77612162
131TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.76307599
132CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.76148263
133SALL4_22934838_ChIP-ChIP_CD34+_Human0.75960189
134HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.74751441
135TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.71275970
136CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.70682085
137NFYB_21822215_ChIP-Seq_K562_Human0.70292008
138ETV1_20927104_ChIP-Seq_GIST48_Human0.70290050

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.11338271
2MP0008877_abnormal_DNA_methylation4.50800303
3MP0010094_abnormal_chromosome_stability4.40559536
4MP0003111_abnormal_nucleus_morphology4.38194320
5MP0003718_maternal_effect4.28383946
6MP0004957_abnormal_blastocyst_morpholog4.02969919
7MP0003077_abnormal_cell_cycle3.60589271
8MP0008057_abnormal_DNA_replication3.53090770
9MP0008058_abnormal_DNA_repair3.08457401
10MP0001929_abnormal_gametogenesis3.02445687
11MP0002653_abnormal_ependyma_morphology2.88708578
12MP0005410_abnormal_fertilization2.87694445
13MP0002210_abnormal_sex_determination2.80690105
14MP0008932_abnormal_embryonic_tissue2.65135097
15MP0003646_muscle_fatigue2.53387466
16MP0001145_abnormal_male_reproductive2.34030636
17MP0000653_abnormal_sex_gland2.33677058
18MP0003123_paternal_imprinting2.32964301
19MP0008789_abnormal_olfactory_epithelium2.27564654
20MP0001730_embryonic_growth_arrest2.22557698
21MP0003698_abnormal_male_reproductive2.18304174
22MP0003786_premature_aging2.11669667
23MP0008007_abnormal_cellular_replicative2.03089353
24MP0005499_abnormal_olfactory_system1.96448475
25MP0005394_taste/olfaction_phenotype1.96448475
26MP0002139_abnormal_hepatobiliary_system1.95987452
27MP0000350_abnormal_cell_proliferation1.95405560
28MP0005451_abnormal_body_composition1.95210044
29MP0009697_abnormal_copulation1.93435269
30MP0004147_increased_porphyrin_level1.91863188
31MP0002102_abnormal_ear_morphology1.91242125
32MP0003315_abnormal_perineum_morphology1.84243496
33MP0006292_abnormal_olfactory_placode1.76865110
34MP0002161_abnormal_fertility/fecundity1.74998616
35MP0005395_other_phenotype1.74838700
36MP0001672_abnormal_embryogenesis/_devel1.71513007
37MP0005380_embryogenesis_phenotype1.71513007
38MP0002085_abnormal_embryonic_tissue1.69310027
39MP0001119_abnormal_female_reproductive1.66882664
40MP0001697_abnormal_embryo_size1.62279864
41MP0003806_abnormal_nucleotide_metabolis1.61945267
42MP0008260_abnormal_autophagy1.61312918
43MP0003699_abnormal_female_reproductive1.59147588
44MP0002084_abnormal_developmental_patter1.51007749
45MP0005360_urolithiasis1.41828649
46MP0003890_abnormal_embryonic-extraembry1.37702136
47MP0003121_genomic_imprinting1.34507373
48MP0003984_embryonic_growth_retardation1.33884314
49MP0002080_prenatal_lethality1.32933169
50MP0002160_abnormal_reproductive_system1.29793427
51MP0002088_abnormal_embryonic_growth/wei1.29237608
52MP0005647_abnormal_sex_gland1.25146568
53MP0005389_reproductive_system_phenotype1.19649421
54MP0002086_abnormal_extraembryonic_tissu1.18131780
55MP0003011_delayed_dark_adaptation1.17503400
56MP0004264_abnormal_extraembryonic_tissu1.16282543
57MP0010307_abnormal_tumor_latency1.15117651
58MP0008995_early_reproductive_senescence1.14381966
59MP0010352_gastrointestinal_tract_polyps1.14142061
60MP0001986_abnormal_taste_sensitivity1.13626381
61MP0010234_abnormal_vibrissa_follicle1.09464169
62MP0003959_abnormal_lean_body1.08962976
63MP0003937_abnormal_limbs/digits/tail_de1.05411208
64MP0003879_abnormal_hair_cell1.03731390
65MP0000313_abnormal_cell_death1.03560850
66MP0003656_abnormal_erythrocyte_physiolo1.03379971
67MP0002249_abnormal_larynx_morphology1.02749369
68MP0002019_abnormal_tumor_incidence1.01425097
69MP0002234_abnormal_pharynx_morphology1.00649113
70MP0005646_abnormal_pituitary_gland0.99556856
71MP0004197_abnormal_fetal_growth/weight/0.99108613
72MP0003119_abnormal_digestive_system0.96805685
73MP0002269_muscular_atrophy0.96619960
74MP0000427_abnormal_hair_cycle0.96401653
75MP0002332_abnormal_exercise_endurance0.95550755
76MP0003186_abnormal_redox_activity0.93738193
77MP0001919_abnormal_reproductive_system0.92017020
78MP0000631_abnormal_neuroendocrine_gland0.91249774
79MP0005266_abnormal_metabolism0.90384035
80MP0000647_abnormal_sebaceous_gland0.90036010
81MP0009379_abnormal_foot_pigmentation0.88786681
82MP0000372_irregular_coat_pigmentation0.87963112
83MP0003787_abnormal_imprinting0.85560253
84MP0000490_abnormal_crypts_of0.84684587
85MP0004145_abnormal_muscle_electrophysio0.82505388
86MP0000358_abnormal_cell_content/0.81220496
87MP0004133_heterotaxia0.80651728
88MP0003950_abnormal_plasma_membrane0.79429351
89MP0002095_abnormal_skin_pigmentation0.77774284
90MP0003861_abnormal_nervous_system0.75103169
91MP0006276_abnormal_autonomic_nervous0.74316234
92MP0005384_cellular_phenotype0.73439863
93MP0004019_abnormal_vitamin_homeostasis0.73126841
94MP0002138_abnormal_hepatobiliary_system0.72893236
95MP0005621_abnormal_cell_physiology0.72155769
96MP0001529_abnormal_vocalization0.71835837
97MP0003136_yellow_coat_color0.70227195
98MP0003938_abnormal_ear_development0.70128917
99MP0001881_abnormal_mammary_gland0.68352165
100MP0001666_abnormal_nutrient_absorption0.66141042
101MP0003936_abnormal_reproductive_system0.65799200
102MP0002127_abnormal_cardiovascular_syste0.65117086
103MP0010030_abnormal_orbit_morphology0.65058341
104MP0005187_abnormal_penis_morphology0.65000984
105MP0003755_abnormal_palate_morphology0.64808886
106MP0000678_abnormal_parathyroid_gland0.63811080
107MP0003567_abnormal_fetal_cardiomyocyte0.63331747
108MP0001545_abnormal_hematopoietic_system0.62440409
109MP0005397_hematopoietic_system_phenotyp0.62440409
110MP0010368_abnormal_lymphatic_system0.62139351
111MP0001293_anophthalmia0.62018676
112MP0002114_abnormal_axial_skeleton0.61512152
113MP0002396_abnormal_hematopoietic_system0.60044455
114MP0001915_intracranial_hemorrhage0.59779307
115MP0006072_abnormal_retinal_apoptosis0.58946670
116MP0002132_abnormal_respiratory_system0.58939496
117MP0003252_abnormal_bile_duct0.58910241
118MP0001502_abnormal_circadian_rhythm0.57975603
119MP0001764_abnormal_homeostasis0.56578690
120MP0005171_absent_coat_pigmentation0.56372375
121MP0005076_abnormal_cell_differentiation0.55229115
122MP0001727_abnormal_embryo_implantation0.55157143
123MP0002796_impaired_skin_barrier0.54629666
124MP0003941_abnormal_skin_development0.54125284
125MP0002282_abnormal_trachea_morphology0.53359161
126MP0005501_abnormal_skin_physiology0.52924534
127MP0002111_abnormal_tail_morphology0.52855098
128MP0006035_abnormal_mitochondrial_morpho0.52550074
129MP0000432_abnormal_head_morphology0.51423149
130MP0009672_abnormal_birth_weight0.50600146
131MP0005408_hypopigmentation0.49704214
132MP0000579_abnormal_nail_morphology0.49653403
133MP0009840_abnormal_foam_cell0.49640948
134MP0001849_ear_inflammation0.48789710
135MP0004233_abnormal_muscle_weight0.47258001
136MP0003935_abnormal_craniofacial_develop0.46498754
137MP0000015_abnormal_ear_pigmentation0.45688343
138MP0000462_abnormal_digestive_system0.45399269
139MP0006036_abnormal_mitochondrial_physio0.45257717
140MP0003221_abnormal_cardiomyocyte_apopto0.44093974
141MP0005670_abnormal_white_adipose0.43781970

Predicted human phenotypes

RankGene SetZ-score
1Cholecystitis (HP:0001082)6.77119282
2Abnormal gallbladder physiology (HP:0012438)6.77119282
3Birth length less than 3rd percentile (HP:0003561)5.03527965
4Breast hypoplasia (HP:0003187)5.00712952
5Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.94244432
6Abnormality of the labia minora (HP:0012880)4.41991400
7Male infertility (HP:0003251)4.05635999
8Chromosomal breakage induced by crosslinking agents (HP:0003221)3.96591685
9Chromsome breakage (HP:0040012)3.93851970
10Premature ovarian failure (HP:0008209)3.91265648
11Supernumerary spleens (HP:0009799)3.76654645
12Patellar aplasia (HP:0006443)3.75693056
13Impulsivity (HP:0100710)3.73737129
14Osteomalacia (HP:0002749)3.71776246
15Absent radius (HP:0003974)3.55776550
16Aplasia/Hypoplasia of the patella (HP:0006498)3.52316853
17Truncus arteriosus (HP:0001660)3.50046007
18Rectal fistula (HP:0100590)3.49452517
19Rectovaginal fistula (HP:0000143)3.49452517
20Carpal bone hypoplasia (HP:0001498)3.44148315
21Aplasia/Hypoplasia of the sacrum (HP:0008517)3.38052708
22Aplasia involving forearm bones (HP:0009822)3.36752629
23Absent forearm bone (HP:0003953)3.36752629
24Ependymoma (HP:0002888)3.14652542
25Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.14506442
26Aplasia/Hypoplasia of the fovea (HP:0008060)3.12114925
27Hypoplasia of the fovea (HP:0007750)3.12114925
28Shawl scrotum (HP:0000049)3.11812871
29Meckel diverticulum (HP:0002245)3.11627576
30Infertility (HP:0000789)3.10008703
31Absent/shortened dynein arms (HP:0200106)3.06384631
32Dynein arm defect of respiratory motile cilia (HP:0012255)3.06384631
33Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.05511274
34Abnormality of the ileum (HP:0001549)3.04734903
35Horseshoe kidney (HP:0000085)3.03124217
36Hypergonadotropic hypogonadism (HP:0000815)3.01539012
37Cerebral hypomyelination (HP:0006808)3.00372723
38Secondary amenorrhea (HP:0000869)3.00141575
39Abnormality of the preputium (HP:0100587)2.98981805
40Degeneration of anterior horn cells (HP:0002398)2.98401554
41Abnormality of the anterior horn cell (HP:0006802)2.98401554
42Intestinal fistula (HP:0100819)2.98281470
43Facial hemangioma (HP:0000329)2.97450252
44Aplasia/Hypoplasia of the uvula (HP:0010293)2.96103032
45Abnormality of DNA repair (HP:0003254)2.92300458
46Vaginal fistula (HP:0004320)2.88923000
47Chronic bronchitis (HP:0004469)2.88920358
48Abnormal respiratory motile cilium physiology (HP:0012261)2.85923997
49Upper limb muscle weakness (HP:0003484)2.83756769
50Abnormality of chromosome stability (HP:0003220)2.81977963
51Reticulocytopenia (HP:0001896)2.80909034
52Abnormality of the fovea (HP:0000493)2.73004381
53Rhabdomyosarcoma (HP:0002859)2.71741993
54Ankyloglossia (HP:0010296)2.66466508
55Abnormal spermatogenesis (HP:0008669)2.65860978
56Duplicated collecting system (HP:0000081)2.64841277
57Abnormality of the lower motor neuron (HP:0002366)2.60806826
58Septate vagina (HP:0001153)2.59218055
59Median cleft lip (HP:0000161)2.56916382
60Duodenal stenosis (HP:0100867)2.56338116
61Small intestinal stenosis (HP:0012848)2.56338116
62Hypophosphatemic rickets (HP:0004912)2.55931115
63Abnormality of the renal collecting system (HP:0004742)2.55860322
64Adrenal hypoplasia (HP:0000835)2.54543434
65Abnormality of sulfur amino acid metabolism (HP:0004339)2.53711006
66Rhinitis (HP:0012384)2.53167519
67Breast aplasia (HP:0100783)2.52810948
68Aplasia/hypoplasia of the humerus (HP:0006507)2.50469054
69Acute myeloid leukemia (HP:0004808)2.49977167
70Medulloblastoma (HP:0002885)2.49650253
71Selective tooth agenesis (HP:0001592)2.49258536
72Homocystinuria (HP:0002156)2.46561042
73Abnormality of homocysteine metabolism (HP:0010919)2.46561042
74Abnormality of reticulocytes (HP:0004312)2.44839559
75Aplasia/Hypoplasia of the breasts (HP:0010311)2.44653397
76Bicornuate uterus (HP:0000813)2.44208992
77Cholelithiasis (HP:0001081)2.43076283
78Sloping forehead (HP:0000340)2.41821989
79Hypokinesia (HP:0002375)2.41378795
80Aplasia/Hypoplasia of the earlobes (HP:0009906)2.39461616
81Ileus (HP:0002595)2.39003588
82Oral leukoplakia (HP:0002745)2.38863537
83Gonadotropin excess (HP:0000837)2.38669117
84Aplasia/Hypoplasia involving the musculature (HP:0001460)2.37738771
85Abnormality of cochlea (HP:0000375)2.37530426
86Abnormal respiratory motile cilium morphology (HP:0005938)2.33196594
87Abnormal respiratory epithelium morphology (HP:0012253)2.33196594
88Lower limb hyperreflexia (HP:0002395)2.31052538
89Polycythemia (HP:0001901)2.30140761
90Absent thumb (HP:0009777)2.28081155
91Reticulocytosis (HP:0001923)2.27754018
92Lip pit (HP:0100267)2.25596339
93Rough bone trabeculation (HP:0100670)2.25126182
94Bowel incontinence (HP:0002607)2.22809310
95Hypoplasia of the capital femoral epiphysis (HP:0003090)2.21079546
96Short humerus (HP:0005792)2.19990562
97Agnosia (HP:0010524)2.19617079
98Anal stenosis (HP:0002025)2.19601017
99Limb hypertonia (HP:0002509)2.16971795
100Aplasia/Hypoplasia of the sternum (HP:0006714)2.16683509
101Atrophy/Degeneration involving motor neurons (HP:0007373)2.15718656
102Oligodactyly (hands) (HP:0001180)2.15544588
103Neoplasm of striated muscle (HP:0009728)2.15185019
104Cortical dysplasia (HP:0002539)2.14742251
105Abnormal large intestine physiology (HP:0012700)2.13722336
106Dysmetric saccades (HP:0000641)2.13156782
107Amyotrophic lateral sclerosis (HP:0007354)2.12930620
108Oligodactyly (HP:0012165)2.12255718
109Tongue fasciculations (HP:0001308)2.11193128
110Neoplasm of the oral cavity (HP:0100649)2.10854723
111Astrocytoma (HP:0009592)2.10770094
112Abnormality of the astrocytes (HP:0100707)2.10770094
113Abnormal gallbladder morphology (HP:0012437)2.10481859
114Aplastic anemia (HP:0001915)2.09435417
115Azoospermia (HP:0000027)2.04008605
116Myelodysplasia (HP:0002863)2.03657154
117Capillary hemangiomas (HP:0005306)2.03551109
118Poikiloderma (HP:0001029)2.01961621
119Abnormal lung lobation (HP:0002101)2.01957408
120Abnormality of the duodenum (HP:0002246)1.99703186
121Bone marrow hypocellularity (HP:0005528)1.99088737
122Short thumb (HP:0009778)1.98472716
123CNS hypomyelination (HP:0003429)1.98439462
124Ureteral duplication (HP:0000073)1.97727821
125Thyroid carcinoma (HP:0002890)1.95925171
126Papillary thyroid carcinoma (HP:0002895)1.94020545
127Anhidrosis (HP:0000970)1.92670907
128Hyperthyroidism (HP:0000836)1.92542524
129Personality changes (HP:0000751)1.91735267
130Increased nuchal translucency (HP:0010880)1.91031285
131Multiple enchondromatosis (HP:0005701)1.90924526
132Absent hand (HP:0004050)1.90172387
133Anterior segment dysgenesis (HP:0007700)1.90064774
134Short tibia (HP:0005736)1.89782239
135Microglossia (HP:0000171)1.89145456
136Pallor (HP:0000980)1.88727220
137Entropion (HP:0000621)1.88152232
138Muscle fibrillation (HP:0010546)1.87973685
139Ectopic kidney (HP:0000086)1.85428835
140Increased serum pyruvate (HP:0003542)1.85315369
141Nephroblastoma (Wilms tumor) (HP:0002667)1.85036684
142Flat capital femoral epiphysis (HP:0003370)1.84871991
143Rib fusion (HP:0000902)1.84541559
144Abnormality of abdominal situs (HP:0011620)1.84094781
145Abdominal situs inversus (HP:0003363)1.84094781
146Cafe-au-lait spot (HP:0000957)1.83874841
147Morphological abnormality of the inner ear (HP:0011390)1.82192423
148Aplasia/Hypoplasia of the tibia (HP:0005772)1.81375068
149Overlapping toe (HP:0001845)1.81372505
150Urethral obstruction (HP:0000796)1.80530029
151Abnormality of the carotid arteries (HP:0005344)1.80417877
152Pancreatic fibrosis (HP:0100732)1.79219027
153Absent septum pellucidum (HP:0001331)1.77699018
154Abnormality of the gallbladder (HP:0005264)1.76115628
155Sandal gap (HP:0001852)1.75926838
156Abnormality of pyrimidine metabolism (HP:0004353)1.73736574
157Choanal atresia (HP:0000453)1.72475843
158Muscle stiffness (HP:0003552)1.70755303
159Proximal tubulopathy (HP:0000114)1.70608340
160Peripheral hypomyelination (HP:0007182)1.70567764
161Hypoparathyroidism (HP:0000829)1.70066585

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTK3.77452132
2BUB13.75511303
3WEE13.73181714
4PDK33.13671505
5PDK43.13671505
6MAP3K133.10261616
7PLK43.08451333
8CDC73.02225222
9NEK22.91200902
10EIF2AK12.48808606
11PBK2.39816487
12PLK12.34133957
13BRAF2.32866859
14LATS22.28396527
15NEK62.20081880
16PDK22.13711329
17STK38L2.08823755
18CHEK22.07303564
19EPHA22.05435009
20NEK12.02616543
21MAP3K61.96761865
22PNCK1.94257680
23AKT31.92903443
24NTRK31.86388696
25ACVR1B1.86287798
26MAP3K91.82199210
27SRPK11.76209241
28ERBB41.68537581
29DYRK31.66283173
30LATS11.60607281
31TESK21.57619828
32CDK121.57617846
33WNK41.57066688
34MAPKAPK31.54832862
35CLK11.49537104
36AURKA1.40189978
37CDK71.40076849
38PLK31.39302929
39EEF2K1.38396155
40TSSK61.33254242
41BRSK21.29837987
42AURKB1.29379259
43DYRK21.28964165
44RPS6KB21.28049269
45STK31.19817585
46KSR21.19520311
47CHEK11.18462502
48TNIK1.18182997
49MELK1.16466055
50ARAF1.16279050
51CCNB11.10267361
52MOS1.10029322
53MET1.09423406
54MAP3K81.08543686
55TESK11.07874716
56CDK191.06586899
57ATR1.06507039
58NME11.06292644
59MUSK1.06175539
60STK391.04455042
61PRKD31.03359366
62TYRO31.02211941
63MST40.97723723
64MAP3K20.97393364
65ICK0.96712499
66STK100.93723579
67WNK10.91171658
68RAF10.89980667
69STK380.88105812
70RIPK40.86579052
71BRSK10.86271714
72VRK10.80504776
73MARK30.80485725
74ATM0.79709548
75CDK40.77618559
76PAK10.76021068
77PRKCI0.75494258
78CDK20.74360518
79STK160.73740876
80CDK80.73385876
81CDK90.73230652
82TAOK10.71609909
83EIF2AK30.70730292
84CDK10.61333776
85PIK3CG0.59707924
86TRPM70.59104505
87PASK0.58454926
88PAK40.56579317
89BRD40.55531565
90PAK60.53769088
91TLK10.52016446
92MKNK20.48298813
93NUAK10.48109936
94MAP3K40.47362708
95PRKAA10.46015583
96MATK0.44513907
97ZAK0.44271932
98DMPK0.43201826
99KSR10.41584384
100MAP2K10.41432335
101AKT20.40579535
102CSNK2A10.40355926
103STK40.39754216
104CSNK1E0.39126177
105LMTK20.38002299
106CSNK2A20.36242098
107PIM10.35980845
108TRIM280.35561842
109TAOK30.34662724
110ABL20.34554916
111MTOR0.32216337
112NME20.31808901
113CSNK1G10.29268716
114PINK10.28642368
115ALK0.28233880
116BMX0.28124383
117MAPKAPK50.27930941
118MAP3K10.27394386
119PKN10.27052889
120CSNK1D0.26865359
121MAPK10.25809044
122BMPR20.22838096
123GSK3B0.22175878
124EIF2AK20.20274904
125MAP3K50.19347988
126LIMK10.17616020
127STK240.17491923
128MAPK100.17268757
129MAPK110.16668358
130MAPK130.16200762
131RPS6KA40.15944706
132MKNK10.15207126
133MAPK140.14050675

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.09235787
2Vitamin B6 metabolism_Homo sapiens_hsa007503.69077378
3Mismatch repair_Homo sapiens_hsa034303.66254309
4RNA transport_Homo sapiens_hsa030133.63396099
5RNA polymerase_Homo sapiens_hsa030203.56731900
6DNA replication_Homo sapiens_hsa030303.55414535
7Cell cycle_Homo sapiens_hsa041103.30736744
8Proteasome_Homo sapiens_hsa030503.17692705
9Basal transcription factors_Homo sapiens_hsa030223.15931957
10Homologous recombination_Homo sapiens_hsa034403.15652556
11Fanconi anemia pathway_Homo sapiens_hsa034602.90839406
12Base excision repair_Homo sapiens_hsa034102.74258724
13Nucleotide excision repair_Homo sapiens_hsa034202.72343453
14Spliceosome_Homo sapiens_hsa030402.50915968
15RNA degradation_Homo sapiens_hsa030182.40887691
16Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.32487738
17Pyrimidine metabolism_Homo sapiens_hsa002402.11816450
18Oocyte meiosis_Homo sapiens_hsa041142.01126443
19mRNA surveillance pathway_Homo sapiens_hsa030151.95377552
20One carbon pool by folate_Homo sapiens_hsa006701.74018032
21p53 signaling pathway_Homo sapiens_hsa041151.73304399
22Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.66814767
23Non-homologous end-joining_Homo sapiens_hsa034501.61108945
24Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.58546300
25Olfactory transduction_Homo sapiens_hsa047401.55543241
26Cysteine and methionine metabolism_Homo sapiens_hsa002701.51674397
27Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.37522017
28Purine metabolism_Homo sapiens_hsa002301.34110528
29Pentose phosphate pathway_Homo sapiens_hsa000301.27941052
30Linoleic acid metabolism_Homo sapiens_hsa005911.27865518
31Regulation of autophagy_Homo sapiens_hsa041401.26968316
32SNARE interactions in vesicular transport_Homo sapiens_hsa041301.17183713
33alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.17062908
34Biosynthesis of amino acids_Homo sapiens_hsa012301.14547008
35Ribosome_Homo sapiens_hsa030101.09301264
36Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.07139908
37Epstein-Barr virus infection_Homo sapiens_hsa051691.03203960
38Folate biosynthesis_Homo sapiens_hsa007900.98998007
39Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.98647481
40Fructose and mannose metabolism_Homo sapiens_hsa000510.98526351
41Circadian rhythm_Homo sapiens_hsa047100.97135885
42Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.96169759
43Glycerophospholipid metabolism_Homo sapiens_hsa005640.91742038
44Fatty acid elongation_Homo sapiens_hsa000620.88339819
45Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.87948160
46Cyanoamino acid metabolism_Homo sapiens_hsa004600.86804651
472-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.86750222
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.79327564
49Selenocompound metabolism_Homo sapiens_hsa004500.78614828
50Propanoate metabolism_Homo sapiens_hsa006400.77971541
51Huntingtons disease_Homo sapiens_hsa050160.77693808
52Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.74947098
53Ether lipid metabolism_Homo sapiens_hsa005650.73704541
54Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.72744470
55mTOR signaling pathway_Homo sapiens_hsa041500.68765068
56Glutathione metabolism_Homo sapiens_hsa004800.68423846
57Hippo signaling pathway_Homo sapiens_hsa043900.68320395
58Caffeine metabolism_Homo sapiens_hsa002320.67922698
59Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.67795749
60Ovarian steroidogenesis_Homo sapiens_hsa049130.66097093
61ABC transporters_Homo sapiens_hsa020100.65717930
62Carbon metabolism_Homo sapiens_hsa012000.61943826
63Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.61769786
64TGF-beta signaling pathway_Homo sapiens_hsa043500.59569772
65Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.58444102
66Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.58405119
67Pyruvate metabolism_Homo sapiens_hsa006200.53870582
68Viral carcinogenesis_Homo sapiens_hsa052030.53702684
69Arachidonic acid metabolism_Homo sapiens_hsa005900.53275740
70Steroid biosynthesis_Homo sapiens_hsa001000.50673498
71MicroRNAs in cancer_Homo sapiens_hsa052060.50121708
72Parkinsons disease_Homo sapiens_hsa050120.49822010
73Hedgehog signaling pathway_Homo sapiens_hsa043400.49058835
74Acute myeloid leukemia_Homo sapiens_hsa052210.47448777
75ErbB signaling pathway_Homo sapiens_hsa040120.46945867
76Arginine biosynthesis_Homo sapiens_hsa002200.46455168
77Sulfur relay system_Homo sapiens_hsa041220.42955151
78Drug metabolism - other enzymes_Homo sapiens_hsa009830.42161866
79Dorso-ventral axis formation_Homo sapiens_hsa043200.41962680
80Systemic lupus erythematosus_Homo sapiens_hsa053220.41065875
81Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.40393116
82Lysine degradation_Homo sapiens_hsa003100.38895170
83Colorectal cancer_Homo sapiens_hsa052100.38874406
84HTLV-I infection_Homo sapiens_hsa051660.36147276
85Protein export_Homo sapiens_hsa030600.35467247
86Metabolic pathways_Homo sapiens_hsa011000.34736291
87N-Glycan biosynthesis_Homo sapiens_hsa005100.34143783
88Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.32753849
89Arginine and proline metabolism_Homo sapiens_hsa003300.31935674
90Phosphatidylinositol signaling system_Homo sapiens_hsa040700.31899097
91Gap junction_Homo sapiens_hsa045400.31277000
92Herpes simplex infection_Homo sapiens_hsa051680.29993925
93Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.29554297
94Taste transduction_Homo sapiens_hsa047420.27680124
95Tight junction_Homo sapiens_hsa045300.27478592
96Longevity regulating pathway - mammal_Homo sapiens_hsa042110.26434764
97Thyroid cancer_Homo sapiens_hsa052160.23834196
98Insulin signaling pathway_Homo sapiens_hsa049100.23135473
99Adherens junction_Homo sapiens_hsa045200.19754158
100Inositol phosphate metabolism_Homo sapiens_hsa005620.19322454
101Synaptic vesicle cycle_Homo sapiens_hsa047210.18393675
102Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.18286726
103Notch signaling pathway_Homo sapiens_hsa043300.17937101
104Fatty acid biosynthesis_Homo sapiens_hsa000610.16625951
105Chronic myeloid leukemia_Homo sapiens_hsa052200.16573576
106Nicotine addiction_Homo sapiens_hsa050330.16383717
107AMPK signaling pathway_Homo sapiens_hsa041520.15655070
108Transcriptional misregulation in cancer_Homo sapiens_hsa052020.15216693
109Glycerolipid metabolism_Homo sapiens_hsa005610.14759082
110Central carbon metabolism in cancer_Homo sapiens_hsa052300.14241888
111Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.13920260
112Basal cell carcinoma_Homo sapiens_hsa052170.13841363
113Pancreatic cancer_Homo sapiens_hsa052120.13813659
114Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.13487685
115Thyroid hormone signaling pathway_Homo sapiens_hsa049190.12763755
116Renal cell carcinoma_Homo sapiens_hsa052110.12201787
117Small cell lung cancer_Homo sapiens_hsa052220.12012526
118FoxO signaling pathway_Homo sapiens_hsa040680.10330496
119Oxidative phosphorylation_Homo sapiens_hsa001900.10230347
120Wnt signaling pathway_Homo sapiens_hsa043100.10212404
121Choline metabolism in cancer_Homo sapiens_hsa052310.09506386
122Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.09385583
123Butanoate metabolism_Homo sapiens_hsa006500.08899323
124Other glycan degradation_Homo sapiens_hsa005110.08241065
125Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.07993171
126Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.06909936
127Maturity onset diabetes of the young_Homo sapiens_hsa049500.06477540
128Bladder cancer_Homo sapiens_hsa052190.04330634
129Antigen processing and presentation_Homo sapiens_hsa046120.03503063
130HIF-1 signaling pathway_Homo sapiens_hsa040660.03428832
131Glucagon signaling pathway_Homo sapiens_hsa049220.01917300

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