NAA16

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA replication checkpoint (GO:0000076)4.37742272
2mitotic metaphase plate congression (GO:0007080)4.32605677
3kinetochore organization (GO:0051383)4.21021087
4negative regulation of translation, ncRNA-mediated (GO:0040033)4.19719956
5regulation of translation, ncRNA-mediated (GO:0045974)4.19719956
6negative regulation of translation involved in gene silencing by miRNA (GO:0035278)4.19719956
7CENP-A containing nucleosome assembly (GO:0034080)4.17804146
8protein localization to kinetochore (GO:0034501)4.15470056
9negative regulation of DNA recombination (GO:0045910)4.09361644
10DNA replication initiation (GO:0006270)4.08737491
11telomere maintenance via semi-conservative replication (GO:0032201)4.08246432
12chromatin remodeling at centromere (GO:0031055)4.02381057
13DNA strand elongation involved in DNA replication (GO:0006271)4.01425038
14metaphase plate congression (GO:0051310)3.92976283
15DNA strand elongation (GO:0022616)3.88065691
16telomere maintenance via recombination (GO:0000722)3.87786156
17nuclear pore complex assembly (GO:0051292)3.81144169
18kinetochore assembly (GO:0051382)3.80810169
19attachment of spindle microtubules to kinetochore (GO:0008608)3.79431176
20mitotic recombination (GO:0006312)3.79052962
21DNA deamination (GO:0045006)3.77046124
22regulation of DNA endoreduplication (GO:0032875)3.74560385
23DNA replication-independent nucleosome assembly (GO:0006336)3.72469225
24DNA replication-independent nucleosome organization (GO:0034724)3.72469225
25nuclear pore organization (GO:0006999)3.70482685
26ribosomal small subunit assembly (GO:0000028)3.69444032
27meiotic chromosome segregation (GO:0045132)3.63912789
28regulation of mitotic spindle checkpoint (GO:1903504)3.58756880
29regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.58756880
30mitotic nuclear envelope disassembly (GO:0007077)3.57934022
31centriole replication (GO:0007099)3.56141500
32protein localization to chromosome, centromeric region (GO:0071459)3.52356103
33telomere maintenance via telomere lengthening (GO:0010833)3.49036815
34establishment of chromosome localization (GO:0051303)3.48529968
35regulation of nuclear cell cycle DNA replication (GO:0033262)3.45968889
36DNA unwinding involved in DNA replication (GO:0006268)3.43839452
37nucleobase biosynthetic process (GO:0046112)3.42462393
38regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.38160650
39synapsis (GO:0007129)3.33908808
40histone exchange (GO:0043486)3.32314174
41purine nucleobase biosynthetic process (GO:0009113)3.30129416
42maturation of SSU-rRNA (GO:0030490)3.29603703
43resolution of meiotic recombination intermediates (GO:0000712)3.26092284
44nuclear envelope disassembly (GO:0051081)3.25807941
45membrane disassembly (GO:0030397)3.25807941
46neural tube formation (GO:0001841)3.24111874
47nucleotide-excision repair, DNA gap filling (GO:0006297)3.22429287
48regulation of helicase activity (GO:0051095)3.22323856
49pore complex assembly (GO:0046931)3.21970590
50histone H2A acetylation (GO:0043968)3.21829285
51regulation of spindle organization (GO:0090224)3.21596319
52recombinational repair (GO:0000725)3.20824554
53maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.20332574
54double-strand break repair via homologous recombination (GO:0000724)3.18688230
55mitotic chromosome condensation (GO:0007076)3.16467371
56DNA ligation (GO:0006266)3.16144644
57IMP biosynthetic process (GO:0006188)3.12415199
58regulation of centriole replication (GO:0046599)3.08712337
59telomere maintenance (GO:0000723)3.06946711
60sister chromatid cohesion (GO:0007062)3.06056983
61ribosome biogenesis (GO:0042254)3.05615393
62telomere organization (GO:0032200)3.05088798
63spindle checkpoint (GO:0031577)3.04811477
64olfactory bulb development (GO:0021772)3.04226046
65monoubiquitinated protein deubiquitination (GO:0035520)3.04034244
66folic acid-containing compound biosynthetic process (GO:0009396)3.02159846
67intraciliary transport (GO:0042073)3.00583799
68intra-S DNA damage checkpoint (GO:0031573)3.00411689
69mismatch repair (GO:0006298)2.99730439
70replication fork processing (GO:0031297)2.98395344
71mitotic sister chromatid segregation (GO:0000070)2.97494063
72formation of translation preinitiation complex (GO:0001731)2.96863165
73protein K6-linked ubiquitination (GO:0085020)2.96433977
74mRNA splice site selection (GO:0006376)2.96301161
75ncRNA catabolic process (GO:0034661)2.94815992
76regulation of meiosis I (GO:0060631)2.94587074
77mitotic sister chromatid cohesion (GO:0007064)2.94220911
78spermatid nucleus differentiation (GO:0007289)2.92434190
79reciprocal DNA recombination (GO:0035825)2.92184661
80reciprocal meiotic recombination (GO:0007131)2.92184661
81negative regulation of DNA-dependent DNA replication (GO:2000104)2.91191747
82ribosome assembly (GO:0042255)2.88849015
83pre-miRNA processing (GO:0031054)2.88116103
84rRNA processing (GO:0006364)2.87437902
85double-strand break repair via nonhomologous end joining (GO:0006303)2.85873389
86non-recombinational repair (GO:0000726)2.85873389
87exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.85497855
88DNA replication-dependent nucleosome assembly (GO:0006335)2.84999644
89DNA replication-dependent nucleosome organization (GO:0034723)2.84999644
90regulation of telomere maintenance (GO:0032204)2.84709126
91ribonucleoprotein complex biogenesis (GO:0022613)2.84499645
92DNA catabolic process, exonucleolytic (GO:0000738)2.83924028
93proteasome assembly (GO:0043248)2.83518652
94regulation of double-strand break repair via homologous recombination (GO:0010569)2.83509060
95spindle assembly checkpoint (GO:0071173)2.82129841
96sister chromatid segregation (GO:0000819)2.82034561
97negative regulation of mitotic sister chromatid separation (GO:2000816)2.81826777
98negative regulation of mitotic sister chromatid segregation (GO:0033048)2.81826777
99negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.81826777
100negative regulation of sister chromatid segregation (GO:0033046)2.81826777
101transcription-coupled nucleotide-excision repair (GO:0006283)2.81806668
102somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.81037195
103isotype switching (GO:0045190)2.81037195
104somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.81037195
105regulation of centrosome duplication (GO:0010824)2.80705069
106negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.80700720
107telomere maintenance via telomerase (GO:0007004)2.80618181
108negative regulation of chromosome segregation (GO:0051985)2.80060067
109rRNA metabolic process (GO:0016072)2.79681981
110ribosomal large subunit biogenesis (GO:0042273)2.79419112
111pseudouridine synthesis (GO:0001522)2.77695070
112DNA geometric change (GO:0032392)2.77572885
113DNA duplex unwinding (GO:0032508)2.76223319
114regulation of mitotic metaphase/anaphase transition (GO:0030071)2.75925764
115regulation of sister chromatid segregation (GO:0033045)2.75812922
116regulation of mitotic sister chromatid separation (GO:0010965)2.75812922
117regulation of mitotic sister chromatid segregation (GO:0033047)2.75812922
118regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.75189743
119mitotic spindle checkpoint (GO:0071174)2.74543723
120rRNA modification (GO:0000154)2.74468711
121microtubule anchoring (GO:0034453)2.74032611
122IMP metabolic process (GO:0046040)2.73546728
123nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.72296317
124mitotic spindle assembly checkpoint (GO:0007094)2.71694859
125mitotic G2/M transition checkpoint (GO:0044818)2.71621626
126behavioral response to nicotine (GO:0035095)2.71238360
127definitive hemopoiesis (GO:0060216)2.70830931
128maturation of 5.8S rRNA (GO:0000460)2.70739128
129DNA replication (GO:0006260)2.69592212
130chromosome segregation (GO:0007059)2.67980243
131regulation of centrosome cycle (GO:0046605)2.67797543
132DNA damage response, detection of DNA damage (GO:0042769)2.67530894
133DNA topological change (GO:0006265)2.66663384
134histone H3-K9 methylation (GO:0051567)2.66120224
135DNA synthesis involved in DNA repair (GO:0000731)2.65691485
136DNA double-strand break processing (GO:0000729)2.65502959
137histone mRNA metabolic process (GO:0008334)2.65370572
138chromatin assembly or disassembly (GO:0006333)2.65354921
139somatic hypermutation of immunoglobulin genes (GO:0016446)2.65216143
140somatic diversification of immune receptors via somatic mutation (GO:0002566)2.65216143
141ATP-dependent chromatin remodeling (GO:0043044)2.64532808
142RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.64016248
143nonmotile primary cilium assembly (GO:0035058)2.62253631
144regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.62216182
145DNA strand renaturation (GO:0000733)2.61444708
146regulation of mRNA splicing, via spliceosome (GO:0048024)2.60194394
147postreplication repair (GO:0006301)2.59533017
148negative regulation of RNA splicing (GO:0033119)2.59437612
149presynaptic membrane assembly (GO:0097105)2.59075108
150somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.58237946
151somatic cell DNA recombination (GO:0016444)2.58237946
152DNA recombination (GO:0006310)2.57918300
153forebrain neuron differentiation (GO:0021879)2.56340249
154somatic diversification of immune receptors (GO:0002200)2.56159296
155negative regulation of mRNA processing (GO:0050686)2.55555795

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.26129645
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.10400599
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.81393940
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.81010544
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.32486659
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.28996124
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.08178334
8ZNF274_21170338_ChIP-Seq_K562_Hela2.87198195
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.84954426
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.59948430
11FUS_26573619_Chip-Seq_HEK293_Human2.59637439
12EWS_26573619_Chip-Seq_HEK293_Human2.59566741
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.57760866
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.56635140
15EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.56466995
16POU3F2_20337985_ChIP-ChIP_501MEL_Human2.51562659
17MYC_19079543_ChIP-ChIP_MESCs_Mouse2.46084804
18IGF1R_20145208_ChIP-Seq_DFB_Human2.44679808
19ETS1_20019798_ChIP-Seq_JURKAT_Human2.44132005
20TAF15_26573619_Chip-Seq_HEK293_Human2.43011782
21MYC_18358816_ChIP-ChIP_MESCs_Mouse2.42709066
22VDR_22108803_ChIP-Seq_LS180_Human2.34508339
23* VDR_23849224_ChIP-Seq_CD4+_Human2.30870270
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.24421688
25E2F1_21310950_ChIP-Seq_MCF-7_Human2.22117546
26ELK1_19687146_ChIP-ChIP_HELA_Human2.20914265
27NELFA_20434984_ChIP-Seq_ESCs_Mouse2.19660908
28CREB1_15753290_ChIP-ChIP_HEK293T_Human2.16933910
29CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.16155869
30HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.15699907
31CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.14921532
32SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.12008106
33PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.03988753
34FOXP3_21729870_ChIP-Seq_TREG_Human2.02895454
35NOTCH1_21737748_ChIP-Seq_TLL_Human2.02754720
36AR_21909140_ChIP-Seq_LNCAP_Human2.02508408
37* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.00765159
38ZFP57_27257070_Chip-Seq_ESCs_Mouse1.98373468
39MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.97353463
40MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.96656162
41GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.95707251
42EGR1_19374776_ChIP-ChIP_THP-1_Human1.92191939
43DCP1A_22483619_ChIP-Seq_HELA_Human1.91858549
44* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.91706987
45MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.89199976
46E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.88273364
47XRN2_22483619_ChIP-Seq_HELA_Human1.88043701
48HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.83713577
49FLI1_27457419_Chip-Seq_LIVER_Mouse1.82522663
50GBX2_23144817_ChIP-Seq_PC3_Human1.82272293
51P300_19829295_ChIP-Seq_ESCs_Human1.81765613
52HOXB4_20404135_ChIP-ChIP_EML_Mouse1.80502181
53E2F1_18555785_ChIP-Seq_MESCs_Mouse1.79281030
54MYCN_18555785_ChIP-Seq_MESCs_Mouse1.77202370
55YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.76633811
56FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.72177718
57CIITA_25753668_ChIP-Seq_RAJI_Human1.70800927
58CTBP2_25329375_ChIP-Seq_LNCAP_Human1.68978605
59POU5F1_16153702_ChIP-ChIP_HESCs_Human1.68064997
60EZH2_22144423_ChIP-Seq_EOC_Human1.67046537
61TP63_19390658_ChIP-ChIP_HaCaT_Human1.65443817
62TTF2_22483619_ChIP-Seq_HELA_Human1.62591022
63NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.59900747
64GABP_19822575_ChIP-Seq_HepG2_Human1.58988216
65TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.56845715
66SRF_21415370_ChIP-Seq_HL-1_Mouse1.55918750
67RBPJ_22232070_ChIP-Seq_NCS_Mouse1.55809067
68SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.53315621
69ERG_20887958_ChIP-Seq_HPC-7_Mouse1.51720085
70HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.49696330
71SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.49312838
72FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.48712578
73IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.47769336
74POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.47691648
75* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.46704803
76AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.44025441
77THAP11_20581084_ChIP-Seq_MESCs_Mouse1.43854439
78SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.43748520
79CTBP1_25329375_ChIP-Seq_LNCAP_Human1.42758267
80YY1_21170310_ChIP-Seq_MESCs_Mouse1.42667391
81CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.42207071
82MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.42087487
83NANOG_18555785_ChIP-Seq_MESCs_Mouse1.39947211
84PCGF2_27294783_Chip-Seq_ESCs_Mouse1.38608568
85ER_23166858_ChIP-Seq_MCF-7_Human1.37409290
86ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.34909424
87* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.32427761
88PADI4_21655091_ChIP-ChIP_MCF-7_Human1.30652483
89MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.30439481
90KDM5A_27292631_Chip-Seq_BREAST_Human1.29389727
91TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29235497
92POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.29235497
93SPI1_23547873_ChIP-Seq_NB4_Human1.27289382
94EZH2_27294783_Chip-Seq_NPCs_Mouse1.25943323
95MYC_18940864_ChIP-ChIP_HL60_Human1.23757005
96GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.21878892
97STAT3_23295773_ChIP-Seq_U87_Human1.21125617
98SALL1_21062744_ChIP-ChIP_HESCs_Human1.20842178
99SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.19265203
100PCGF2_27294783_Chip-Seq_NPCs_Mouse1.19167282
101SMAD4_21799915_ChIP-Seq_A2780_Human1.19005140
102IRF8_22096565_ChIP-ChIP_GC-B_Human1.17470032
103BCAT_22108803_ChIP-Seq_LS180_Human1.17181679
104ZFX_18555785_ChIP-Seq_MESCs_Mouse1.17016677
105IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.16695755
106CBP_20019798_ChIP-Seq_JUKART_Human1.16695755
107GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.16661028
108OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14310012
109MYC_22102868_ChIP-Seq_BL_Human1.14128154
110E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.14123600
111FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.13389640
112SUZ12_27294783_Chip-Seq_NPCs_Mouse1.13122918
113SOX2_16153702_ChIP-ChIP_HESCs_Human1.12923345
114RNF2_27304074_Chip-Seq_NSC_Mouse1.12661018
115ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.11224116
116HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.11178170
117TOP2B_26459242_ChIP-Seq_MCF-7_Human1.10883676
118ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.10703795
119TCF4_23295773_ChIP-Seq_U87_Human1.10055779
120ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.09595118
121PIAS1_25552417_ChIP-Seq_VCAP_Human1.09305700
122EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.08904228
123BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.08220968
124TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06598495
125DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.06482066
126NFE2_27457419_Chip-Seq_LIVER_Mouse1.06376724
127PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.05906812
128SMAD3_21741376_ChIP-Seq_EPCs_Human1.05325968
129PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.05130938
130CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.05060191
131MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.03890531
132TFEB_21752829_ChIP-Seq_HELA_Human1.03381634
133AR_25329375_ChIP-Seq_VCAP_Human1.02166151
134NANOG_16153702_ChIP-ChIP_HESCs_Human1.01563667
135IRF8_21731497_ChIP-ChIP_J774_Mouse1.00849398
136TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.00412596
137RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.99562940
138RUNX2_22187159_ChIP-Seq_PCA_Human0.98876426
139RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97954087
140NANOG_18555785_Chip-Seq_ESCs_Mouse0.97788175
141FLI1_21867929_ChIP-Seq_TH2_Mouse0.97494465
142MYB_26560356_Chip-Seq_TH1_Human0.97256567
143SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.97041348
144NR3C1_21868756_ChIP-Seq_MCF10A_Human0.96125526
145KLF5_20875108_ChIP-Seq_MESCs_Mouse0.95611113
146TCF4_22108803_ChIP-Seq_LS180_Human0.95249244
147CBX2_27304074_Chip-Seq_ESCs_Mouse0.94889960
148STAT4_19710469_ChIP-ChIP_TH1__Mouse0.93900719
149TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.93751560
150MYB_26560356_Chip-Seq_TH2_Human0.92284668
151EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.91948092
152POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.90780731
153CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.89514001
154SOX9_26525672_Chip-Seq_HEART_Mouse0.88403001
155SOX2_18555785_ChIP-Seq_MESCs_Mouse0.88402369
156IRF1_19129219_ChIP-ChIP_H3396_Human0.86303054
157MYB_21317192_ChIP-Seq_ERMYB_Mouse0.86077670
158GATA1_22025678_ChIP-Seq_K562_Human0.83473738
159CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.81302171
160SCL_19346495_ChIP-Seq_HPC-7_Human0.81280394
161STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.78852213
162BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.77505871
163KLF4_18555785_ChIP-Seq_MESCs_Mouse0.74080297
164FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71682792
165CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.71017735
166CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.70858334
167ELK1_22589737_ChIP-Seq_MCF10A_Human0.70803892
168SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.69780946

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.79997332
2MP0008057_abnormal_DNA_replication4.45510317
3MP0010094_abnormal_chromosome_stability4.30930744
4MP0003111_abnormal_nucleus_morphology3.81819179
5MP0008058_abnormal_DNA_repair3.60984312
6MP0003077_abnormal_cell_cycle3.52265960
7MP0004957_abnormal_blastocyst_morpholog3.45156519
8MP0002396_abnormal_hematopoietic_system3.25308856
9MP0008007_abnormal_cellular_replicative3.20602930
10MP0003890_abnormal_embryonic-extraembry2.54901809
11MP0003880_abnormal_central_pattern2.36445798
12MP0000569_abnormal_digit_pigmentation2.21507509
13MP0003763_abnormal_thymus_physiology2.18912302
14MP0008932_abnormal_embryonic_tissue1.97403206
15MP0008877_abnormal_DNA_methylation1.96406014
16MP0006072_abnormal_retinal_apoptosis1.87629782
17MP0003786_premature_aging1.85058755
18MP0000490_abnormal_crypts_of1.78030579
19MP0000350_abnormal_cell_proliferation1.76592179
20MP0009333_abnormal_splenocyte_physiolog1.74180671
21MP0004808_abnormal_hematopoietic_stem1.73587615
22MP0001835_abnormal_antigen_presentation1.67866712
23MP0000631_abnormal_neuroendocrine_gland1.65786935
24MP0003567_abnormal_fetal_cardiomyocyte1.63811538
25MP0003937_abnormal_limbs/digits/tail_de1.60966426
26MP0006292_abnormal_olfactory_placode1.60455354
27MP0001730_embryonic_growth_arrest1.60222742
28MP0003718_maternal_effect1.59987521
29MP0000778_abnormal_nervous_system1.55927146
30MP0005671_abnormal_response_to1.53266244
31MP0002398_abnormal_bone_marrow1.51899553
32MP0001529_abnormal_vocalization1.50296135
33MP0003123_paternal_imprinting1.44061230
34MP0001545_abnormal_hematopoietic_system1.42983250
35MP0005397_hematopoietic_system_phenotyp1.42983250
36MP0001485_abnormal_pinna_reflex1.42975836
37MP0003122_maternal_imprinting1.42432365
38MP0010307_abnormal_tumor_latency1.41524323
39MP0001286_abnormal_eye_development1.39755963
40MP0000703_abnormal_thymus_morphology1.39395902
41MP0003136_yellow_coat_color1.37957003
42MP0002233_abnormal_nose_morphology1.37028105
43MP0003943_abnormal_hepatobiliary_system1.36920605
44MP0006276_abnormal_autonomic_nervous1.36609216
45MP0002132_abnormal_respiratory_system1.36415674
46MP0000049_abnormal_middle_ear1.35919738
47MP0005253_abnormal_eye_physiology1.35660927
48MP0002019_abnormal_tumor_incidence1.35288609
49MP0005380_embryogenesis_phenotype1.35128020
50MP0001672_abnormal_embryogenesis/_devel1.35128020
51MP0002736_abnormal_nociception_after1.34629093
52MP0001800_abnormal_humoral_immune1.34312631
53MP0002751_abnormal_autonomic_nervous1.34275831
54MP0001853_heart_inflammation1.33979000
55MP0000313_abnormal_cell_death1.33508594
56MP0000689_abnormal_spleen_morphology1.32897730
57MP0004742_abnormal_vestibular_system1.32482822
58MP0002722_abnormal_immune_system1.32148681
59MP0002163_abnormal_gland_morphology1.29653346
60MP0003938_abnormal_ear_development1.29373780
61MP0008995_early_reproductive_senescence1.28801586
62MP0005551_abnormal_eye_electrophysiolog1.27020553
63MP0009697_abnormal_copulation1.25061568
64MP0008789_abnormal_olfactory_epithelium1.24812169
65MP0001188_hyperpigmentation1.22545485
66MP0000427_abnormal_hair_cycle1.22477796
67MP0003984_embryonic_growth_retardation1.22397391
68MP0001697_abnormal_embryo_size1.21536231
69MP0003119_abnormal_digestive_system1.20808081
70MP0002429_abnormal_blood_cell1.19776156
71MP0002452_abnormal_antigen_presenting1.19479680
72MP0002088_abnormal_embryonic_growth/wei1.18993377
73MP0002420_abnormal_adaptive_immunity1.18404870
74MP0002006_tumorigenesis1.17736892
75MP0000716_abnormal_immune_system1.17222404
76MP0004142_abnormal_muscle_tone1.16827252
77MP0001819_abnormal_immune_cell1.16421488
78MP0006054_spinal_hemorrhage1.14452908
79MP0000566_synostosis1.14342713
80MP0001873_stomach_inflammation1.13872005
81MP0004133_heterotaxia1.13700545
82MP0002086_abnormal_extraembryonic_tissu1.13486424
83MP0003121_genomic_imprinting1.13004615
84MP0001486_abnormal_startle_reflex1.12684829
85MP0001119_abnormal_female_reproductive1.10999778
86MP0001986_abnormal_taste_sensitivity1.08873492
87MP0001984_abnormal_olfaction1.07419570
88MP0002080_prenatal_lethality1.06056242
89MP0002166_altered_tumor_susceptibility1.05381361
90MP0002723_abnormal_immune_serum1.05254387
91MP0009785_altered_susceptibility_to1.05052846
92MP0003646_muscle_fatigue1.04290578
93MP0009703_decreased_birth_body1.03121861
94MP0010352_gastrointestinal_tract_polyps1.03112966
95MP0002210_abnormal_sex_determination1.02630841
96MP0002234_abnormal_pharynx_morphology1.02565452
97MP0005391_vision/eye_phenotype1.02268970
98MP0005075_abnormal_melanosome_morpholog1.01517781
99MP0003861_abnormal_nervous_system1.01346895
100MP0003941_abnormal_skin_development1.00811159
101MP0005367_renal/urinary_system_phenotyp1.00293072
102MP0000516_abnormal_urinary_system1.00293072
103MP0003755_abnormal_palate_morphology1.00275016
104MP0002697_abnormal_eye_size0.99651881
105MP0005394_taste/olfaction_phenotype0.98838729
106MP0005499_abnormal_olfactory_system0.98838729
107MP0005000_abnormal_immune_tolerance0.98187627
108MP0003698_abnormal_male_reproductive0.98083859
109MP0002102_abnormal_ear_morphology0.97892474
110MP0002085_abnormal_embryonic_tissue0.97811973
111MP0000465_gastrointestinal_hemorrhage0.96602949
112MP0002405_respiratory_system_inflammati0.95592799
113MP0002095_abnormal_skin_pigmentation0.94761002
114MP0004147_increased_porphyrin_level0.93211146
115MP0000858_altered_metastatic_potential0.92257465
116MP0000015_abnormal_ear_pigmentation0.89717168
117MP0002938_white_spotting0.89666792
118MP0001968_abnormal_touch/_nociception0.89256201
119MP0009046_muscle_twitch0.88966210
120MP0000647_abnormal_sebaceous_gland0.88832291
121MP0002822_catalepsy0.87404344
122MP0004885_abnormal_endolymph0.86677698
123MP0001145_abnormal_male_reproductive0.86323856
124MP0003828_pulmonary_edema0.85329595
125MP0010155_abnormal_intestine_physiology0.85052412
126MP0005387_immune_system_phenotype0.84191609
127MP0001790_abnormal_immune_system0.84191609
128MP0000653_abnormal_sex_gland0.82606354
129MP0005025_abnormal_response_to0.82515102
130MP0005248_abnormal_Harderian_gland0.82438523
131MP0002084_abnormal_developmental_patter0.82138596
132MP0002184_abnormal_innervation0.81320696
133MP0000685_abnormal_immune_system0.80549034
134MP0000428_abnormal_craniofacial_morphol0.80001971
135MP0003186_abnormal_redox_activity0.79833580
136MP0003787_abnormal_imprinting0.79602273
137MP0003283_abnormal_digestive_organ0.79572960
138MP0005195_abnormal_posterior_eye0.78987758
139MP0005174_abnormal_tail_pigmentation0.78753548
140MP0000955_abnormal_spinal_cord0.77779049
141MP0003724_increased_susceptibility_to0.77165859
142MP0005379_endocrine/exocrine_gland_phen0.76853504
143MP0002752_abnormal_somatic_nervous0.76656555
144MP0001915_intracranial_hemorrhage0.76618223
145MP0001177_atelectasis0.76617278
146MP0001324_abnormal_eye_pigmentation0.76115984
147MP0001929_abnormal_gametogenesis0.76072075
148MP0002419_abnormal_innate_immunity0.75864010
149MP0002009_preneoplasia0.75036461
150MP0002152_abnormal_brain_morphology0.74327133
151MP0004197_abnormal_fetal_growth/weight/0.73805200
152MP0002272_abnormal_nervous_system0.72765154
153MP0003935_abnormal_craniofacial_develop0.72161060
154MP0001919_abnormal_reproductive_system0.70836834
155MP0005389_reproductive_system_phenotype0.70647959
156MP0002148_abnormal_hypersensitivity_rea0.70161275
157MP0009379_abnormal_foot_pigmentation0.69342204
158MP0003806_abnormal_nucleotide_metabolis0.69016479
159MP0004264_abnormal_extraembryonic_tissu0.68251650
160MP0001293_anophthalmia0.67842806
161MP0005409_darkened_coat_color0.64958062

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.87941172
2Chromsome breakage (HP:0040012)4.65568170
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.35929678
4Reticulocytopenia (HP:0001896)3.53738364
5Abnormality of chromosome stability (HP:0003220)3.53438376
6Abnormality of the preputium (HP:0100587)3.40524068
7Chronic hepatic failure (HP:0100626)3.32968826
8Pancreatic cysts (HP:0001737)3.30693972
9Pancreatic fibrosis (HP:0100732)3.14338245
10Meckel diverticulum (HP:0002245)3.11621389
11Aplastic anemia (HP:0001915)3.11549416
12Oral leukoplakia (HP:0002745)3.11493441
13Molar tooth sign on MRI (HP:0002419)3.05431666
14Abnormality of midbrain morphology (HP:0002418)3.05431666
15True hermaphroditism (HP:0010459)3.03737172
16Intestinal atresia (HP:0011100)3.03711427
17Breast hypoplasia (HP:0003187)3.01219589
18Abnormality of the ileum (HP:0001549)2.95990585
19Myelodysplasia (HP:0002863)2.93825082
20Nephronophthisis (HP:0000090)2.93218341
21IgM deficiency (HP:0002850)2.87488834
22Patellar aplasia (HP:0006443)2.86471739
23Degeneration of anterior horn cells (HP:0002398)2.84589474
24Abnormality of the anterior horn cell (HP:0006802)2.84589474
25Ectopic kidney (HP:0000086)2.83314076
26Aplasia/Hypoplasia of the uvula (HP:0010293)2.80996168
27Aplasia/Hypoplasia of the patella (HP:0006498)2.62983667
28Bone marrow hypocellularity (HP:0005528)2.59449872
29Medulloblastoma (HP:0002885)2.59013623
30Abnormality of DNA repair (HP:0003254)2.58324029
31Impulsivity (HP:0100710)2.57209851
32Small intestinal stenosis (HP:0012848)2.56969308
33Duodenal stenosis (HP:0100867)2.56969308
34Acute myeloid leukemia (HP:0004808)2.54547950
35Premature graying of hair (HP:0002216)2.53510032
36Lymphoma (HP:0002665)2.50285935
37Microretrognathia (HP:0000308)2.48638593
38Abnormality of the fingertips (HP:0001211)2.46214984
39Abnormal number of erythroid precursors (HP:0012131)2.44138458
40Absent radius (HP:0003974)2.43289542
41Colon cancer (HP:0003003)2.43141585
42Abnormality of the renal medulla (HP:0100957)2.43019027
43Abnormal lung lobation (HP:0002101)2.39814854
4411 pairs of ribs (HP:0000878)2.39351475
45Abnormality of B cell number (HP:0010975)2.38266191
46B lymphocytopenia (HP:0010976)2.38266191
47Rough bone trabeculation (HP:0100670)2.37193483
48Abnormality of T cell physiology (HP:0011840)2.34807667
49Medial flaring of the eyebrow (HP:0010747)2.34247269
50Duplicated collecting system (HP:0000081)2.31859350
51Rhabdomyosarcoma (HP:0002859)2.30981468
52Clubbing of toes (HP:0100760)2.29160924
53Panhypogammaglobulinemia (HP:0003139)2.28993915
54Aqueductal stenosis (HP:0002410)2.28624119
55Sloping forehead (HP:0000340)2.28508731
56Abnormality of cells of the erythroid lineage (HP:0012130)2.27559002
57Nephroblastoma (Wilms tumor) (HP:0002667)2.26523799
58Septo-optic dysplasia (HP:0100842)2.25736694
59Abnormality of T cells (HP:0002843)2.24984919
60Postaxial foot polydactyly (HP:0001830)2.24341310
61Selective tooth agenesis (HP:0001592)2.23510875
62Ependymoma (HP:0002888)2.22763623
63Agnosia (HP:0010524)2.22469382
64Prominent nose (HP:0000448)2.21645402
65Abnormality of the columella (HP:0009929)2.21105085
66Glioma (HP:0009733)2.20655704
67Type I transferrin isoform profile (HP:0003642)2.19688180
68Petechiae (HP:0000967)2.19600215
69Oligodactyly (hands) (HP:0001180)2.19403133
70Aplasia involving forearm bones (HP:0009822)2.19338430
71Absent forearm bone (HP:0003953)2.19338430
72Abnormality of the renal collecting system (HP:0004742)2.17985125
73Abnormality of the renal cortex (HP:0011035)2.16238426
74Abnormality of the duodenum (HP:0002246)2.13924572
75Hyperventilation (HP:0002883)2.13358946
76Supernumerary spleens (HP:0009799)2.13117431
77Cellular immunodeficiency (HP:0005374)2.11652687
78Hyperglycinemia (HP:0002154)2.10950019
79Embryonal renal neoplasm (HP:0011794)2.09842142
80Cystic liver disease (HP:0006706)2.09488060
81Anencephaly (HP:0002323)2.07661342
82Abnormal biliary tract physiology (HP:0012439)2.07142126
83Bile duct proliferation (HP:0001408)2.07142126
84Abnormality of the astrocytes (HP:0100707)2.06831402
85Astrocytoma (HP:0009592)2.06831402
86Horseshoe kidney (HP:0000085)2.03677780
87Abnormal number of incisors (HP:0011064)2.02540657
88Absent thumb (HP:0009777)1.99680444
89Leukopenia (HP:0001882)1.99161053
90Triphalangeal thumb (HP:0001199)1.98413364
91Aplasia/Hypoplasia of the spleen (HP:0010451)1.98237098
92Small hand (HP:0200055)1.98016869
93Abnormality of the prostate (HP:0008775)1.97765053
94Optic nerve hypoplasia (HP:0000609)1.97651985
95Gastrointestinal atresia (HP:0002589)1.96426630
96Abnormality of lateral ventricle (HP:0030047)1.96311056
97Pallor (HP:0000980)1.96091869
98Drooling (HP:0002307)1.95843765
99IgG deficiency (HP:0004315)1.95597125
100Postaxial hand polydactyly (HP:0001162)1.94219728
101Aplasia/Hypoplasia of the tongue (HP:0010295)1.94108282
102Pendular nystagmus (HP:0012043)1.93839778
103Thrombocytosis (HP:0001894)1.93560545
104Pancytopenia (HP:0001876)1.93251858
105Bifid tongue (HP:0010297)1.90435900
106Abnormal trabecular bone morphology (HP:0100671)1.89343576
107Congenital primary aphakia (HP:0007707)1.88931957
108Neoplasm of the pancreas (HP:0002894)1.88893998
109Cortical dysplasia (HP:0002539)1.88649947
110Squamous cell carcinoma (HP:0002860)1.88363172
111Preaxial hand polydactyly (HP:0001177)1.88299276
112Recurrent viral infections (HP:0004429)1.88204554
113Volvulus (HP:0002580)1.88094179
114Abnormal hair whorl (HP:0010721)1.87705471
115T lymphocytopenia (HP:0005403)1.87578748
116Poikiloderma (HP:0001029)1.87431668
117Genital tract atresia (HP:0001827)1.87316230
118Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.86336968
119Hepatoblastoma (HP:0002884)1.86214339
120Entropion (HP:0000621)1.86175695
121Narrow forehead (HP:0000341)1.86054230
122Encephalitis (HP:0002383)1.85958093
123Myositis (HP:0100614)1.84931786
124Pulmonary fibrosis (HP:0002206)1.84864728
125Abnormality of the labia minora (HP:0012880)1.84015786
126Gait imbalance (HP:0002141)1.83427383
127Basal cell carcinoma (HP:0002671)1.83284737
128Retrobulbar optic neuritis (HP:0100654)1.82019863
129Optic neuritis (HP:0100653)1.82019863
130Growth hormone deficiency (HP:0000824)1.81825448
131Long eyelashes (HP:0000527)1.81673996
132Tracheoesophageal fistula (HP:0002575)1.81261541
133Nephrogenic diabetes insipidus (HP:0009806)1.81198433
134Protruding tongue (HP:0010808)1.80774013
135Capillary hemangiomas (HP:0005306)1.80109944
136Sclerocornea (HP:0000647)1.79834214
137Excessive salivation (HP:0003781)1.79807668
138Vaginal atresia (HP:0000148)1.79425644
139Methylmalonic acidemia (HP:0002912)1.79323685
140Carpal bone hypoplasia (HP:0001498)1.79122665
141Poor coordination (HP:0002370)1.78173922
142Biliary tract neoplasm (HP:0100574)1.76734069
143Cupped ear (HP:0000378)1.76635557
144Highly arched eyebrow (HP:0002553)1.76556904
145Asplenia (HP:0001746)1.76249850
146Abnormality of the carotid arteries (HP:0005344)1.76169730
147Abnormality of T cell number (HP:0011839)1.75209614
148Gaze-evoked nystagmus (HP:0000640)1.75188292
149Broad-based gait (HP:0002136)1.75127672
150Combined immunodeficiency (HP:0005387)1.74899888
151Astigmatism (HP:0000483)1.74898357
152Renal cortical cysts (HP:0000803)1.74766381
153Dandy-Walker malformation (HP:0001305)1.74702307
154Anophthalmia (HP:0000528)1.74129540
155Premature ovarian failure (HP:0008209)1.74002299
156Genetic anticipation (HP:0003743)1.73392587
157Abnormality of the septum pellucidum (HP:0007375)1.73068172
158Short thumb (HP:0009778)1.73000544
159Severe combined immunodeficiency (HP:0004430)1.72869843
160Tubulointerstitial nephritis (HP:0001970)1.72274786
161Oligodactyly (HP:0012165)1.71983314
162IgA deficiency (HP:0002720)1.71264086
163Lissencephaly (HP:0001339)1.70864109
164Lip pit (HP:0100267)1.70487788
165Oculomotor apraxia (HP:0000657)1.70242613
166Absent septum pellucidum (HP:0001331)1.68133020
167Neoplasm of the adrenal cortex (HP:0100641)1.68105625
168Febrile seizures (HP:0002373)1.67803139
169Aplasia/Hypoplasia of the sternum (HP:0006714)1.64798543
170Progressive inability to walk (HP:0002505)1.64375336

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE14.01645792
2CDC73.67922994
3WEE13.03362922
4BUB12.93849835
5SRPK12.68410089
6FRK2.66711926
7STK162.39885740
8EIF2AK12.33721294
9TSSK62.27701517
10PLK42.26309114
11WNK32.21951496
12TTK2.21021155
13TXK2.16337665
14TRIM282.15941542
15PNCK2.15444973
16MAP4K12.14285335
17ACVR1B2.11506715
18MKNK22.10910871
19VRK12.05558975
20TEC2.04379277
21MKNK12.02031266
22CASK1.81947315
23NEK21.78838462
24BCR1.78320522
25EIF2AK31.76362502
26ZAK1.74733974
27IRAK31.74141527
28NME21.70739584
29ATR1.63829677
30BRSK21.62597013
31PLK11.55749695
32MAP4K21.55275964
33TLK11.52201876
34MAP3K41.44803900
35RPS6KA41.42321995
36MAPK131.41241511
37AURKB1.38949204
38CDK71.35983574
39TAF11.34986496
40NLK1.33951404
41PLK31.33217074
42STK101.26930264
43CHEK21.26262513
44PASK1.25966196
45BRD41.21809229
46ERBB31.21044846
47NEK91.20553560
48PBK1.18825501
49EIF2AK21.17964340
50IRAK41.17818812
51STK41.17320077
52FGFR21.15308733
53CDK121.11398427
54MAP3K101.08976645
55TGFBR11.08373787
56DYRK31.07014879
57CDK41.06717971
58PIM21.02907073
59CAMK1G1.01898084
60CAMKK21.00856594
61DYRK21.00282509
62CHEK11.00130644
63AKT30.98383657
64ATM0.98364829
65BRAF0.98180702
66PAK30.97706926
67CDK80.97105142
68SIK30.95622245
69CSNK1G10.95402431
70PIM10.94271282
71CCNB10.94261902
72GRK10.93808211
73NUAK10.89793380
74PINK10.89504935
75BLK0.87390581
76KDR0.86287505
77CDK190.84710427
78CLK10.83434751
79ZAP700.83316821
80SGK20.82711064
81JAK30.82102017
82RPS6KB20.81659919
83STK390.81650069
84MAP3K140.79544250
85CSNK1G20.79096891
86OXSR10.73270578
87MAP3K80.73014430
88BTK0.69790500
89FLT30.67092683
90KIT0.67042681
91CSNK1G30.66033761
92YES10.65856989
93AURKA0.65754965
94ADRBK20.65469795
95RPS6KA50.64355589
96MAP2K70.62759138
97CSNK1A1L0.62529694
98MST40.62138674
99CHUK0.62118031
100STK30.61851394
101TAOK30.60956835
102CDK20.60034873
103CDK60.59943902
104DYRK1A0.58712182
105MARK30.58200729
106MAP2K30.57705008
107IKBKB0.57613150
108MELK0.57385691
109CSNK2A10.56833391
110FGFR10.55807319
111TYK20.55508816
112NTRK20.54662821
113BRSK10.53700025
114CSNK2A20.53688997
115PRKCG0.53573578
116BMPR1B0.52940437
117CDK30.52800551
118WNK40.52252111
119KSR10.51881125
120VRK20.51407503
121MAP3K60.50830443
122LATS10.50723302
123PLK20.50459913
124TESK20.49316805
125INSRR0.48947714
126CDK10.48895908
127SGK2230.45082013
128SGK4940.45082013
129LYN0.44700269
130CSNK1D0.44329832
131UHMK10.43261185
132MAP3K50.42938419
133BMPR20.42302449
134CSF1R0.40557063
135CSNK1E0.40303673
136STK38L0.40268286
137CAMK40.39845973
138NEK10.39845740
139TRPM70.39800326
140IKBKE0.39165641
141CAMK1D0.37720079
142IRAK10.36674693
143ITK0.36499011
144PRKDC0.36119571
145STK110.36017932
146LCK0.35658813
147STK240.35073736
148PIK3CA0.34544175
149TNIK0.30750776

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.46292522
2Mismatch repair_Homo sapiens_hsa034303.85232398
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.57048749
4Homologous recombination_Homo sapiens_hsa034403.28546040
5Base excision repair_Homo sapiens_hsa034103.11667509
6RNA polymerase_Homo sapiens_hsa030202.97793363
7Spliceosome_Homo sapiens_hsa030402.82286039
8Non-homologous end-joining_Homo sapiens_hsa034502.81657315
9Fanconi anemia pathway_Homo sapiens_hsa034602.77019171
10RNA transport_Homo sapiens_hsa030132.69260525
11Nucleotide excision repair_Homo sapiens_hsa034202.64622480
12Cell cycle_Homo sapiens_hsa041102.64129289
13Ribosome_Homo sapiens_hsa030102.63702544
14Proteasome_Homo sapiens_hsa030502.45900204
15RNA degradation_Homo sapiens_hsa030182.42530253
16One carbon pool by folate_Homo sapiens_hsa006702.36268196
17Pyrimidine metabolism_Homo sapiens_hsa002402.27465711
18Basal transcription factors_Homo sapiens_hsa030222.09362932
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.89904538
20Steroid biosynthesis_Homo sapiens_hsa001001.85462127
21Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.84820746
22Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.80794760
23Primary immunodeficiency_Homo sapiens_hsa053401.68930489
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.64588234
25p53 signaling pathway_Homo sapiens_hsa041151.62009252
26Phototransduction_Homo sapiens_hsa047441.60049729
27mRNA surveillance pathway_Homo sapiens_hsa030151.44801087
28Herpes simplex infection_Homo sapiens_hsa051681.44307120
29Propanoate metabolism_Homo sapiens_hsa006401.43369666
30Nicotine addiction_Homo sapiens_hsa050331.40664679
31Protein export_Homo sapiens_hsa030601.30648576
32Purine metabolism_Homo sapiens_hsa002301.28670829
33Antigen processing and presentation_Homo sapiens_hsa046121.23936930
34Lysine degradation_Homo sapiens_hsa003101.15107765
35Epstein-Barr virus infection_Homo sapiens_hsa051691.14626786
36NF-kappa B signaling pathway_Homo sapiens_hsa040641.13690684
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.10700019
38Intestinal immune network for IgA production_Homo sapiens_hsa046721.05907436
39Basal cell carcinoma_Homo sapiens_hsa052171.05667502
40Measles_Homo sapiens_hsa051621.04140679
41Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.03533060
42Huntingtons disease_Homo sapiens_hsa050161.03277523
43Allograft rejection_Homo sapiens_hsa053300.98918845
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.98914260
45Hematopoietic cell lineage_Homo sapiens_hsa046400.98134287
46Systemic lupus erythematosus_Homo sapiens_hsa053220.92987046
47Oxidative phosphorylation_Homo sapiens_hsa001900.92680072
48Parkinsons disease_Homo sapiens_hsa050120.90433877
49Hedgehog signaling pathway_Homo sapiens_hsa043400.87044898
50Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.86020052
51Transcriptional misregulation in cancer_Homo sapiens_hsa052020.85359447
52Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.83543919
53Folate biosynthesis_Homo sapiens_hsa007900.83314271
54Legionellosis_Homo sapiens_hsa051340.80786166
55Viral carcinogenesis_Homo sapiens_hsa052030.79296902
56Butanoate metabolism_Homo sapiens_hsa006500.78443294
57HTLV-I infection_Homo sapiens_hsa051660.77746613
58Vitamin B6 metabolism_Homo sapiens_hsa007500.76934029
59NOD-like receptor signaling pathway_Homo sapiens_hsa046210.76672832
60Wnt signaling pathway_Homo sapiens_hsa043100.76211441
61Linoleic acid metabolism_Homo sapiens_hsa005910.74965784
62Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.74389252
63Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.74282756
64Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.73152369
65Ether lipid metabolism_Homo sapiens_hsa005650.73085261
66Hippo signaling pathway_Homo sapiens_hsa043900.71055512
67Autoimmune thyroid disease_Homo sapiens_hsa053200.70815532
68Graft-versus-host disease_Homo sapiens_hsa053320.70372430
69RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.69724740
70Taste transduction_Homo sapiens_hsa047420.63950091
71Nitrogen metabolism_Homo sapiens_hsa009100.63111834
72Thyroid cancer_Homo sapiens_hsa052160.62868022
73Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.62150766
74Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.61761802
75MicroRNAs in cancer_Homo sapiens_hsa052060.61289254
76Hepatitis B_Homo sapiens_hsa051610.59470977
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.58884025
78Oocyte meiosis_Homo sapiens_hsa041140.58515731
79Influenza A_Homo sapiens_hsa051640.58218125
80Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.57350469
81Leishmaniasis_Homo sapiens_hsa051400.57001849
82Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.55321547
83Drug metabolism - other enzymes_Homo sapiens_hsa009830.55314680
84Jak-STAT signaling pathway_Homo sapiens_hsa046300.54631514
85Apoptosis_Homo sapiens_hsa042100.54398650
86Long-term depression_Homo sapiens_hsa047300.54138391
87Olfactory transduction_Homo sapiens_hsa047400.50488129
88T cell receptor signaling pathway_Homo sapiens_hsa046600.47053783
89Alcoholism_Homo sapiens_hsa050340.46620176
90Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.46586803
91Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.45051152
92Asthma_Homo sapiens_hsa053100.44647654
93Dopaminergic synapse_Homo sapiens_hsa047280.44399092
94TGF-beta signaling pathway_Homo sapiens_hsa043500.43481171
95Selenocompound metabolism_Homo sapiens_hsa004500.42491917
96Pentose phosphate pathway_Homo sapiens_hsa000300.42007856
97Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.41288500
98Small cell lung cancer_Homo sapiens_hsa052220.41149572
99Serotonergic synapse_Homo sapiens_hsa047260.40568114
100Cysteine and methionine metabolism_Homo sapiens_hsa002700.40418467
101Morphine addiction_Homo sapiens_hsa050320.39759621
102Notch signaling pathway_Homo sapiens_hsa043300.39590153
103Type I diabetes mellitus_Homo sapiens_hsa049400.39087124
104Acute myeloid leukemia_Homo sapiens_hsa052210.38932451
105Circadian entrainment_Homo sapiens_hsa047130.37790316
106Alzheimers disease_Homo sapiens_hsa050100.36876940
107Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.36547985
108Shigellosis_Homo sapiens_hsa051310.36254873
109Axon guidance_Homo sapiens_hsa043600.34679952
110Arachidonic acid metabolism_Homo sapiens_hsa005900.34027655
111Glutamatergic synapse_Homo sapiens_hsa047240.33687961
112Glycerolipid metabolism_Homo sapiens_hsa005610.32997012
113Prostate cancer_Homo sapiens_hsa052150.31346617
114Glutathione metabolism_Homo sapiens_hsa004800.30355292
115HIF-1 signaling pathway_Homo sapiens_hsa040660.30005833
116Viral myocarditis_Homo sapiens_hsa054160.29997647
117B cell receptor signaling pathway_Homo sapiens_hsa046620.29730782
118Cyanoamino acid metabolism_Homo sapiens_hsa004600.29666711
119Peroxisome_Homo sapiens_hsa041460.28822593
120Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.28001097
121Metabolic pathways_Homo sapiens_hsa011000.26505850
122Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.25244371
123Regulation of autophagy_Homo sapiens_hsa041400.24944003
124GABAergic synapse_Homo sapiens_hsa047270.24350308
125Colorectal cancer_Homo sapiens_hsa052100.24330987
126Adherens junction_Homo sapiens_hsa045200.23626662
127Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.23109926
128Amphetamine addiction_Homo sapiens_hsa050310.22782559
129Toll-like receptor signaling pathway_Homo sapiens_hsa046200.22362529
130Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.22253845
131Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.21308524
132Endometrial cancer_Homo sapiens_hsa052130.19504695
133Toxoplasmosis_Homo sapiens_hsa051450.19227086
134Maturity onset diabetes of the young_Homo sapiens_hsa049500.18996409
135N-Glycan biosynthesis_Homo sapiens_hsa005100.18726251
136Sulfur relay system_Homo sapiens_hsa041220.18284998
137Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.17790480
138Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.17653537
139Pathways in cancer_Homo sapiens_hsa052000.17496844
140Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.16794769
141Other glycan degradation_Homo sapiens_hsa005110.16266939
142Cholinergic synapse_Homo sapiens_hsa047250.15283273
143FoxO signaling pathway_Homo sapiens_hsa040680.15033896
144Malaria_Homo sapiens_hsa051440.14816797
145Pancreatic cancer_Homo sapiens_hsa052120.14528223
146Circadian rhythm_Homo sapiens_hsa047100.13834075
147Tuberculosis_Homo sapiens_hsa051520.13811480
148Longevity regulating pathway - mammal_Homo sapiens_hsa042110.13311274
149Melanoma_Homo sapiens_hsa052180.12685449
150Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.11589333
151Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.10410333

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