NAA30

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic chromosome condensation (GO:0007076)5.40401116
2monoubiquitinated protein deubiquitination (GO:0035520)5.35858324
3mitotic metaphase plate congression (GO:0007080)5.33690413
4histone H2A monoubiquitination (GO:0035518)5.06051761
5regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.58672865
6metaphase plate congression (GO:0051310)4.42530766
7regulation of RNA export from nucleus (GO:0046831)4.38978189
8nuclear pore complex assembly (GO:0051292)4.36819391
9mitotic sister chromatid cohesion (GO:0007064)4.35461750
10piRNA metabolic process (GO:0034587)4.27516493
11cytoplasmic mRNA processing body assembly (GO:0033962)4.25991799
12female gamete generation (GO:0007292)4.24848890
13regulation of transforming growth factor beta2 production (GO:0032909)4.19226820
14labyrinthine layer development (GO:0060711)4.18712852
15negative regulation of retinoic acid receptor signaling pathway (GO:0048387)4.16672658
16attachment of spindle microtubules to kinetochore (GO:0008608)4.16230526
17positive regulation of mitotic sister chromatid separation (GO:1901970)4.12673542
18positive regulation of mitotic metaphase/anaphase transition (GO:0045842)4.12673542
19positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)4.12673542
20regulation of meiosis I (GO:0060631)4.10559523
21regulation of sister chromatid cohesion (GO:0007063)4.06598656
22histone H2A ubiquitination (GO:0033522)4.04935998
23regulation of histone H3-K27 methylation (GO:0061085)4.02314149
24meiotic cell cycle (GO:0051321)3.99103527
25interkinetic nuclear migration (GO:0022027)3.98902754
26synapsis (GO:0007129)3.92748286
27establishment of chromosome localization (GO:0051303)3.89284815
28nuclear pore organization (GO:0006999)3.82768463
29positive regulation of chromosome segregation (GO:0051984)3.78948655
30protein localization to kinetochore (GO:0034501)3.77407062
31histone lysine demethylation (GO:0070076)3.75106602
32regulation of nucleobase-containing compound transport (GO:0032239)3.74887759
33oocyte maturation (GO:0001556)3.72876848
34protein localization to chromosome, centromeric region (GO:0071459)3.64037592
35regulation of DNA methylation (GO:0044030)3.61951511
36histone demethylation (GO:0016577)3.61841514
37regulation of establishment of cell polarity (GO:2000114)3.60973030
38sister chromatid cohesion (GO:0007062)3.60784945
39muscle filament sliding (GO:0030049)3.57647496
40actin-myosin filament sliding (GO:0033275)3.57647496
41regulation of clathrin-mediated endocytosis (GO:2000369)3.52351547
42histone H3-K9 demethylation (GO:0033169)3.51424179
43protein localization to chromosome (GO:0034502)3.50929445
44meiotic chromosome segregation (GO:0045132)3.47503217
45male meiosis I (GO:0007141)3.47032612
46regulation of spindle organization (GO:0090224)3.46678899
47negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.45883698
48negative regulation of histone methylation (GO:0031061)3.45349139
49actin-mediated cell contraction (GO:0070252)3.44069724
50regulation of establishment or maintenance of cell polarity (GO:0032878)3.43704421
51regulation of meiosis (GO:0040020)3.43276173
52negative regulation of meiosis (GO:0045835)3.34320898
53protein K6-linked ubiquitination (GO:0085020)3.30816516
54regulation of female gonad development (GO:2000194)3.30803831
55DNA damage induced protein phosphorylation (GO:0006975)3.29515492
56histone monoubiquitination (GO:0010390)3.28804445
57male meiosis (GO:0007140)3.23956728
58DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla3.23719358
59regulation of mitotic spindle organization (GO:0060236)3.23137761
60negative regulation of hormone metabolic process (GO:0032351)3.21725899
61negative regulation of hormone biosynthetic process (GO:0032353)3.21725899
62pre-miRNA processing (GO:0031054)3.19293596
63intestinal epithelial cell development (GO:0060576)3.13109571
64spindle checkpoint (GO:0031577)3.12691314
65histone exchange (GO:0043486)3.12534335
66sarcoplasmic reticulum calcium ion transport (GO:0070296)3.11439212
67protein dealkylation (GO:0008214)3.10487150
68protein demethylation (GO:0006482)3.10487150
69regulation of cAMP-dependent protein kinase activity (GO:2000479)3.09649571
70meiosis I (GO:0007127)3.08686309
71gene silencing by RNA (GO:0031047)3.07243921
72regulation of retinoic acid receptor signaling pathway (GO:0048385)3.06884296
73DNA damage response, signal transduction resulting in transcription (GO:0042772)3.06555879
74snRNA transcription (GO:0009301)3.06486747
75positive regulation of meiosis (GO:0045836)3.04921551
76negative regulation of potassium ion transmembrane transport (GO:1901380)3.04222885
77kinetochore organization (GO:0051383)3.03215274
78primitive streak formation (GO:0090009)3.03024741
79nodal signaling pathway (GO:0038092)3.02102966
80chromatin remodeling at centromere (GO:0031055)3.00931512
81chromosome organization involved in meiosis (GO:0070192)3.00135622
82peptidyl-threonine dephosphorylation (GO:0035970)2.98803221
83resolution of meiotic recombination intermediates (GO:0000712)2.97469092
84protein monoubiquitination (GO:0006513)2.94811201
85regulation of chromosome segregation (GO:0051983)2.94593039
86histone ubiquitination (GO:0016574)2.94510317
87establishment of spindle localization (GO:0051293)2.94178938
88DNA replication-independent nucleosome assembly (GO:0006336)2.90567888
89DNA replication-independent nucleosome organization (GO:0034724)2.90567888
90somite rostral/caudal axis specification (GO:0032525)2.88383665
91protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.87394412
92chromatin assembly or disassembly (GO:0006333)2.87038167
93synaptonemal complex assembly (GO:0007130)2.84507613
94microtubule nucleation (GO:0007020)2.83305560
95type B pancreatic cell development (GO:0003323)2.82543761
96CENP-A containing nucleosome assembly (GO:0034080)2.82093214
97regulation of hippo signaling (GO:0035330)2.81543781
98SMAD protein complex assembly (GO:0007183)2.81336695
99peptidyl-threonine phosphorylation (GO:0018107)2.79741156
100positive regulation of meiotic cell cycle (GO:0051446)2.79435836
101sister chromatid segregation (GO:0000819)2.79065063
102notochord development (GO:0030903)2.78373725
103skeletal muscle contraction (GO:0003009)2.78180954
104nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.76823286
105positive regulation of megakaryocyte differentiation (GO:0045654)2.76455669
106chromosome segregation (GO:0007059)2.76391713
107regulation of centriole replication (GO:0046599)2.75635800
108response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.75445134
109positive regulation of male gonad development (GO:2000020)2.75422558
110regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.73879854
111centriole replication (GO:0007099)2.72776434
112membrane disassembly (GO:0030397)2.72560322
113nuclear envelope disassembly (GO:0051081)2.72560322
114pore complex assembly (GO:0046931)2.71844011
115meiotic cell cycle process (GO:1903046)2.70364733
116mitotic nuclear envelope disassembly (GO:0007077)2.70338609
117mitotic sister chromatid segregation (GO:0000070)2.70247023
118regulation of relaxation of muscle (GO:1901077)2.69956341
119anterior/posterior axis specification, embryo (GO:0008595)2.67996423
120regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.67548530
121peptidyl-threonine modification (GO:0018210)2.65505428
122chromatin assembly (GO:0031497)2.64711463
123oogenesis (GO:0048477)2.64367244
124DNA methylation involved in gamete generation (GO:0043046)2.64357396
125regulation of telomere maintenance via telomerase (GO:0032210)2.63966895
126regulation of DNA endoreduplication (GO:0032875)2.58531122
127regulation of histone H3-K9 methylation (GO:0051570)2.58101807
128Golgi to endosome transport (GO:0006895)2.56928049
129vesicle transport along microtubule (GO:0047496)2.53870193
130negative regulation of NF-kappaB import into nucleus (GO:0042347)2.52919178
131regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.49532633
132regulation of skeletal muscle contraction (GO:0014819)2.48942432
133synaptonemal complex organization (GO:0070193)2.48450199
134actin filament-based movement (GO:0030048)2.48292739
135regulation of meiotic cell cycle (GO:0051445)2.45482961
136embryonic foregut morphogenesis (GO:0048617)2.45167664
137sarcomere organization (GO:0045214)2.44921250
138regulation of male gonad development (GO:2000018)2.42888172
139striated muscle contraction (GO:0006941)2.42739996
140regulation of cell communication by electrical coupling (GO:0010649)2.42117706
141negative regulation of meiotic cell cycle (GO:0051447)2.40353490
142hippo signaling (GO:0035329)2.36331366
143prenylation (GO:0097354)2.36147796
144protein prenylation (GO:0018342)2.36147796
145positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.36115976
146acrosome assembly (GO:0001675)2.34600350
147DNA synthesis involved in DNA repair (GO:0000731)2.33591699
148oocyte development (GO:0048599)2.31317317
149intracellular lipid transport (GO:0032365)2.31110311
150nucleus localization (GO:0051647)2.30939142
151keratinocyte development (GO:0003334)2.30782210
152paraxial mesoderm development (GO:0048339)2.29012852
153atrial cardiac muscle cell action potential (GO:0086014)2.28276399
154protein K63-linked deubiquitination (GO:0070536)2.28005812
155regulation of centrosome cycle (GO:0046605)2.26716694
156myofibril assembly (GO:0030239)2.26502303
157regulation of energy homeostasis (GO:2000505)2.25529805
158histone-serine phosphorylation (GO:0035404)2.24418964
159genitalia morphogenesis (GO:0035112)2.24121231
160response to inactivity (GO:0014854)2.24037174
161cellular protein complex localization (GO:0034629)2.23898160
162fatty acid homeostasis (GO:0055089)2.23453291
163ventricular cardiac muscle cell action potential (GO:0086005)2.22516384
164phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.22176131
165positive regulation of catenin import into nucleus (GO:0035413)2.22042093
166cardiac muscle hypertrophy (GO:0003300)2.22002074
167negative regulation of DNA-dependent DNA replication (GO:2000104)2.21808505
168pyrimidine dimer repair (GO:0006290)2.21792313

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human4.81680660
2E2F7_22180533_ChIP-Seq_HELA_Human3.91534933
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.89666053
4RBPJ_22232070_ChIP-Seq_NCS_Mouse3.27662076
5* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.79576511
6SMAD_19615063_ChIP-ChIP_OVARY_Human2.78962502
7TCF3_18467660_ChIP-ChIP_MESCs_Mouse2.76393713
8GBX2_23144817_ChIP-Seq_PC3_Human2.75326256
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.62072111
10SALL4_18804426_ChIP-ChIP_MESCs_Mouse2.59631917
11AR_21909140_ChIP-Seq_LNCAP_Human2.56936215
12BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.56464767
13FUS_26573619_Chip-Seq_HEK293_Human2.41077838
14ZFP57_27257070_Chip-Seq_ESCs_Mouse2.26829381
15EZH2_22144423_ChIP-Seq_EOC_Human2.20967216
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.15439463
17E2F4_17652178_ChIP-ChIP_JURKAT_Human2.14645652
18ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.09146775
19CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.08523291
20POU3F2_20337985_ChIP-ChIP_501MEL_Human2.01091645
21NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.97210397
22FLI1_27457419_Chip-Seq_LIVER_Mouse1.96555782
23AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.91657732
24GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.83411132
25TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.82062415
26NOTCH1_21737748_ChIP-Seq_TLL_Human1.80802061
27NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.79315032
28SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.76788121
29EP300_21415370_ChIP-Seq_HL-1_Mouse1.76679860
30CBP_20019798_ChIP-Seq_JUKART_Human1.72658242
31IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.72658242
32FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.71847634
33TAF15_26573619_Chip-Seq_HEK293_Human1.71634421
34STAT6_21828071_ChIP-Seq_BEAS2B_Human1.66014593
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.65578687
36IGF1R_20145208_ChIP-Seq_DFB_Human1.65391468
37FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.63216193
38ZNF274_21170338_ChIP-Seq_K562_Hela1.62287671
39SMAD4_21799915_ChIP-Seq_A2780_Human1.60068163
40EWS_26573619_Chip-Seq_HEK293_Human1.59464021
41FOXM1_26456572_ChIP-Seq_MCF-7_Human1.55562822
42ER_23166858_ChIP-Seq_MCF-7_Human1.52136915
43TOP2B_26459242_ChIP-Seq_MCF-7_Human1.51289309
44RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.51259060
45PKCTHETA_26484144_Chip-Seq_BREAST_Human1.49946733
46MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.47086591
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.47004216
48ZNF217_24962896_ChIP-Seq_MCF-7_Human1.46884436
49PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.45941280
50TP53_16413492_ChIP-PET_HCT116_Human1.45170204
51ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.44918626
52* VDR_22108803_ChIP-Seq_LS180_Human1.44672413
53PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.43978704
54UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.41872153
55MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.41761598
56FOXO3_23340844_ChIP-Seq_DLD1_Human1.41245325
57CDX2_19796622_ChIP-Seq_MESCs_Mouse1.41000360
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.40430337
59KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.38678978
60KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.38678978
61KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.38678978
62CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.38487045
63AR_25329375_ChIP-Seq_VCAP_Human1.35807628
64STAT3_23295773_ChIP-Seq_U87_Human1.32645483
65NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.30924304
66HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.29822424
67KAP1_22055183_ChIP-Seq_ESCs_Mouse1.29703847
68NRF2_20460467_ChIP-Seq_MEFs_Mouse1.29252055
69NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.29252055
70FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.29175793
71PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.29128343
72NANOG_18555785_Chip-Seq_ESCs_Mouse1.29020236
73FLI1_21867929_ChIP-Seq_TH2_Mouse1.27203330
74STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.27088593
75NR3C1_21868756_ChIP-Seq_MCF10A_Human1.26352083
76SMAD4_21741376_ChIP-Seq_EPCs_Human1.25741295
77TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25179096
78POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.25179096
79PIAS1_25552417_ChIP-Seq_VCAP_Human1.23712824
80TP63_19390658_ChIP-ChIP_HaCaT_Human1.23364623
81SALL4_18804426_ChIP-ChIP_XEN_Mouse1.22966818
82PCGF2_27294783_Chip-Seq_ESCs_Mouse1.22855475
83ESR1_20079471_ChIP-ChIP_T-47D_Human1.22731437
84TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.19885419
85E2F1_18555785_Chip-Seq_ESCs_Mouse1.19076997
86TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17823407
87PCGF2_27294783_Chip-Seq_NPCs_Mouse1.17672939
88RNF2_27304074_Chip-Seq_NSC_Mouse1.15453589
89TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.15069684
90TBX3_20139965_ChIP-Seq_ESCs_Mouse1.14653820
91TBX3_20139965_ChIP-Seq_MESCs_Mouse1.14405157
92KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.13089948
93EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.12509421
94CDX2_22108803_ChIP-Seq_LS180_Human1.12290577
95CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.11557671
96BCAT_22108803_ChIP-Seq_LS180_Human1.11089655
97TBL1_22424771_ChIP-Seq_293T_Human1.10999851
98CRX_20693478_ChIP-Seq_RETINA_Mouse1.09987426
99CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.09950629
100CTBP2_25329375_ChIP-Seq_LNCAP_Human1.09904442
101OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09017863
102TCF3_18692474_ChIP-Seq_MESCs_Mouse1.08877870
103AHR_22903824_ChIP-Seq_MCF-7_Human1.08417096
104NANOG_21062744_ChIP-ChIP_HESCs_Human1.08213669
105CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07914665
106* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.07625596
107GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.06772783
108P53_22387025_ChIP-Seq_ESCs_Mouse1.06254548
109SUZ12_18555785_Chip-Seq_ESCs_Mouse1.06178420
110CMYC_18555785_Chip-Seq_ESCs_Mouse1.05717745
111PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.05291928
112SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05130299
113PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.05069268
114TCF4_18268006_ChIP-ChIP_LS174T_Human1.04285507
115NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.04192126
116OCT4_21477851_ChIP-Seq_ESCs_Mouse1.03292788
117BRD4_25478319_ChIP-Seq_HGPS_Human1.02948187
118SOX2_21211035_ChIP-Seq_LN229_Gbm1.02774492
119RUNX2_22187159_ChIP-Seq_PCA_Human1.02335864
120YAP1_20516196_ChIP-Seq_MESCs_Mouse1.02001083
121RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01533070
122CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.00323257
123P300_19829295_ChIP-Seq_ESCs_Human1.00129920
124RXR_22108803_ChIP-Seq_LS180_Human1.00114670
125NR3C1_23031785_ChIP-Seq_PC12_Mouse0.99822324
126PPAR_26484153_Chip-Seq_NCI-H1993_Human0.98710037
127CBX2_27304074_Chip-Seq_ESCs_Mouse0.98577425
128POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.98346513
129TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.97477016
130ZNF263_19887448_ChIP-Seq_K562_Human0.96649549
131STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.95865262
132EZH2_27294783_Chip-Seq_NPCs_Mouse0.94702775
133CHD1_26751641_Chip-Seq_LNCaP_Human0.92448397
134DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.91762476
135LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89048676
136TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.88305703
137MYCN_18555785_ChIP-Seq_MESCs_Mouse0.88158582
138TP63_23658742_ChIP-Seq_EP156T_Human0.87404924
139* CTBP1_25329375_ChIP-Seq_LNCAP_Human0.87267261
140NFYA_21822215_ChIP-Seq_K562_Human0.87211771
141SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.87195858
142TCF4_23295773_ChIP-Seq_U87_Human0.86689985
143RUNX1_26923725_Chip-Seq_HPCs_Mouse0.86042928
144NFE2_27457419_Chip-Seq_LIVER_Mouse0.85923725
145GF1B_26923725_Chip-Seq_HPCs_Mouse0.85237404
146GATA1_26923725_Chip-Seq_HPCs_Mouse0.84257369
147* FOXA1_25552417_ChIP-Seq_VCAP_Human0.84054575
148TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.82511026
149KLF4_18555785_ChIP-Seq_MESCs_Mouse0.82409077
150SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.82259087

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle4.66897320
2MP0003123_paternal_imprinting3.47394449
3MP0003693_abnormal_embryo_hatching3.23149104
4MP0004145_abnormal_muscle_electrophysio2.84411339
5MP0005451_abnormal_body_composition2.61886753
6MP0008877_abnormal_DNA_methylation2.57147999
7MP0008057_abnormal_DNA_replication2.49351797
8MP0003787_abnormal_imprinting2.47714950
9MP0003890_abnormal_embryonic-extraembry2.47516792
10MP0003718_maternal_effect2.45403176
11MP0004185_abnormal_adipocyte_glucose2.35940775
12MP0004957_abnormal_blastocyst_morpholog2.33505920
13MP0003077_abnormal_cell_cycle2.24889370
14MP0002877_abnormal_melanocyte_morpholog2.18233907
15MP0003937_abnormal_limbs/digits/tail_de2.16510363
16MP0003705_abnormal_hypodermis_morpholog2.15812592
17MP0003111_abnormal_nucleus_morphology2.14618309
18MP0010094_abnormal_chromosome_stability2.14507549
19MP0000569_abnormal_digit_pigmentation2.08291779
20MP0010678_abnormal_skin_adnexa2.03493014
21MP0002837_dystrophic_cardiac_calcinosis2.01064452
22MP0003950_abnormal_plasma_membrane1.99168917
23MP0010352_gastrointestinal_tract_polyps1.98570275
24MP0004215_abnormal_myocardial_fiber1.97265435
25MP0004084_abnormal_cardiac_muscle1.95835773
26MP0002160_abnormal_reproductive_system1.93979608
27MP0002084_abnormal_developmental_patter1.92911823
28MP0005076_abnormal_cell_differentiation1.92833571
29MP0002102_abnormal_ear_morphology1.90572182
30MP0001730_embryonic_growth_arrest1.90054231
31MP0000579_abnormal_nail_morphology1.87744123
32MP0004036_abnormal_muscle_relaxation1.84642302
33MP0000749_muscle_degeneration1.79847949
34MP0000013_abnormal_adipose_tissue1.78258862
35MP0004233_abnormal_muscle_weight1.76618308
36MP0003121_genomic_imprinting1.76583473
37MP0001849_ear_inflammation1.72240672
38MP0010368_abnormal_lymphatic_system1.64724220
39MP0000350_abnormal_cell_proliferation1.62708594
40MP0005620_abnormal_muscle_contractility1.62203572
41MP0010307_abnormal_tumor_latency1.60774955
42MP0001929_abnormal_gametogenesis1.60012452
43MP0000747_muscle_weakness1.59203790
44MP0000566_synostosis1.59038396
45MP0002085_abnormal_embryonic_tissue1.58748992
46MP0009697_abnormal_copulation1.58307277
47MP0003699_abnormal_female_reproductive1.57050235
48MP0002106_abnormal_muscle_physiology1.56174787
49MP0009780_abnormal_chondrocyte_physiolo1.54662195
50MP0001672_abnormal_embryogenesis/_devel1.54515471
51MP0005380_embryogenesis_phenotype1.54515471
52MP0002332_abnormal_exercise_endurance1.53546392
53MP0000751_myopathy1.52705869
54MP0001119_abnormal_female_reproductive1.52660029
55MP0001697_abnormal_embryo_size1.51934235
56MP0005408_hypopigmentation1.49368723
57MP0000653_abnormal_sex_gland1.48905850
58MP0004270_analgesia1.48038904
59MP0003646_muscle_fatigue1.47741859
60MP0002086_abnormal_extraembryonic_tissu1.47167702
61MP0004130_abnormal_muscle_cell1.46825964
62MP0004087_abnormal_muscle_fiber1.46268037
63MP0002210_abnormal_sex_determination1.45995735
64MP0001346_abnormal_lacrimal_gland1.45824662
65MP0003941_abnormal_skin_development1.45200097
66MP0003453_abnormal_keratinocyte_physiol1.44314067
67MP0004264_abnormal_extraembryonic_tissu1.39900299
68MP0001984_abnormal_olfaction1.39152739
69MP0004484_altered_response_of1.36247059
70MP0002269_muscular_atrophy1.36050162
71MP0002653_abnormal_ependyma_morphology1.34640769
72MP0001879_abnormal_lymphatic_vessel1.32861133
73MP0001661_extended_life_span1.32411746
74MP0002234_abnormal_pharynx_morphology1.32188748
75MP0002088_abnormal_embryonic_growth/wei1.29366466
76MP0003984_embryonic_growth_retardation1.27673925
77MP0000427_abnormal_hair_cycle1.24017444
78MP0003567_abnormal_fetal_cardiomyocyte1.21781094
79MP0003868_abnormal_feces_composition1.21152635
80MP0003755_abnormal_palate_morphology1.20324832
81MP0001145_abnormal_male_reproductive1.20317427
82MP0005369_muscle_phenotype1.18942475
83MP0009672_abnormal_birth_weight1.18636878
84MP0002796_impaired_skin_barrier1.18490546
85MP0005647_abnormal_sex_gland1.17598291
86MP0000759_abnormal_skeletal_muscle1.17509187
87MP0000733_abnormal_muscle_development1.17095383
88MP0009053_abnormal_anal_canal1.14829186
89MP0002972_abnormal_cardiac_muscle1.14343110
90MP0001851_eye_inflammation1.12741185
91MP0000383_abnormal_hair_follicle1.12349250
92MP0001293_anophthalmia1.10309220
93MP0004197_abnormal_fetal_growth/weight/1.10260786
94MP0003221_abnormal_cardiomyocyte_apopto1.08947960
95MP0002138_abnormal_hepatobiliary_system1.08215716
96MP0008932_abnormal_embryonic_tissue1.07806178
97MP0008007_abnormal_cellular_replicative1.07394942
98MP0000537_abnormal_urethra_morphology1.06334948
99MP0005666_abnormal_adipose_tissue1.05103001
100MP0005187_abnormal_penis_morphology1.04180768
101MP0003119_abnormal_digestive_system1.03460105
102MP0005395_other_phenotype1.03368144
103MP0004133_heterotaxia1.02709232
104MP0001915_intracranial_hemorrhage1.02414851
105MP0002127_abnormal_cardiovascular_syste0.99747992
106MP0003943_abnormal_hepatobiliary_system0.99700572
107MP0003861_abnormal_nervous_system0.98172707
108MP0001340_abnormal_eyelid_morphology0.96151400
109MP0000647_abnormal_sebaceous_gland0.95385082
110MP0009384_cardiac_valve_regurgitation0.93330785
111MP0003935_abnormal_craniofacial_develop0.93052509
112MP0006292_abnormal_olfactory_placode0.92823977
113MP0005389_reproductive_system_phenotype0.91854069
114MP0004885_abnormal_endolymph0.91046283
115MP0010630_abnormal_cardiac_muscle0.91019798
116MP0002638_abnormal_pupillary_reflex0.90571269
117MP0002161_abnormal_fertility/fecundity0.89957580
118MP0002139_abnormal_hepatobiliary_system0.88744252
119MP0009046_muscle_twitch0.87996394
120MP0000432_abnormal_head_morphology0.87394372
121MP0003385_abnormal_body_wall0.86801062
122MP0000639_abnormal_adrenal_gland0.85837106
123MP0000465_gastrointestinal_hemorrhage0.83287114
124MP0002233_abnormal_nose_morphology0.83260155
125MP0008058_abnormal_DNA_repair0.83250263
126MP0005248_abnormal_Harderian_gland0.82991261
127MP0002080_prenatal_lethality0.82989557
128MP0001485_abnormal_pinna_reflex0.82948291
129MP0005266_abnormal_metabolism0.82284074
130MP0009703_decreased_birth_body0.82205712
131MP0008995_early_reproductive_senescence0.82136955
132MP0005379_endocrine/exocrine_gland_phen0.81987787
133MP0005360_urolithiasis0.81486274
134MP0002697_abnormal_eye_size0.81078247
135MP0003959_abnormal_lean_body0.80735424
136MP0000750_abnormal_muscle_regeneration0.80636147
137MP0000627_abnormal_mammary_gland0.80512603
138MP0001188_hyperpigmentation0.79982207
139MP0000778_abnormal_nervous_system0.79384937
140MP0000428_abnormal_craniofacial_morphol0.78458750
141MP0003698_abnormal_male_reproductive0.78029884
142MP0000266_abnormal_heart_morphology0.77651952
143MP0005330_cardiomyopathy0.76805480
144MP0001299_abnormal_eye_distance/0.75894232
145MP0001216_abnormal_epidermal_layer0.75804302
146MP0004924_abnormal_behavior0.73945974
147MP0005310_abnormal_salivary_gland0.72969793
148MP0003936_abnormal_reproductive_system0.72745035
149MP0000377_abnormal_hair_follicle0.72544834
150MP0001286_abnormal_eye_development0.72153325
151MP0005085_abnormal_gallbladder_physiolo0.72141075
152MP0003315_abnormal_perineum_morphology0.69939594
153MP0002009_preneoplasia0.68468521

Predicted human phenotypes

RankGene SetZ-score
1Papillary thyroid carcinoma (HP:0002895)5.92386123
2Muscle fiber inclusion bodies (HP:0100299)5.60295060
3Nemaline bodies (HP:0003798)5.57993801
4Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)5.43839367
5Facial hemangioma (HP:0000329)4.76634223
6Male infertility (HP:0003251)4.50295904
7Abnormality of the labia minora (HP:0012880)4.05326688
8Exercise-induced muscle cramps (HP:0003710)4.03272910
9Calf muscle hypertrophy (HP:0008981)3.75724784
10Muscle hypertrophy of the lower extremities (HP:0008968)3.74843852
11Abnormality of the left ventricular outflow tract (HP:0011103)3.49719090
12Subaortic stenosis (HP:0001682)3.49719090
13Rimmed vacuoles (HP:0003805)3.49637383
14Lip pit (HP:0100267)3.43882202
15Thyroid carcinoma (HP:0002890)3.41386327
16Type 1 muscle fiber predominance (HP:0003803)3.37380864
17Exercise-induced myalgia (HP:0003738)3.35456097
18Abnormality of lateral ventricle (HP:0030047)3.27215637
19Distal arthrogryposis (HP:0005684)3.16595366
20Termporal pattern (HP:0011008)3.16230703
21Insidious onset (HP:0003587)3.16230703
22Fair hair (HP:0002286)3.06888578
23Birth length less than 3rd percentile (HP:0003561)3.03819327
24Bundle branch block (HP:0011710)3.03511087
25Sandal gap (HP:0001852)3.00345188
26Oligodactyly (hands) (HP:0001180)2.96319386
27Cortical dysplasia (HP:0002539)2.96080042
28Shoulder girdle muscle weakness (HP:0003547)2.92814385
29Hypoplastic labia majora (HP:0000059)2.91243608
30Hyporeflexia of lower limbs (HP:0002600)2.83315085
31Abnormality of the labia majora (HP:0012881)2.77430384
32Shawl scrotum (HP:0000049)2.74153392
33Capillary hemangiomas (HP:0005306)2.73729794
34Abnormality of the calf musculature (HP:0001430)2.71706444
35Breast hypoplasia (HP:0003187)2.71026413
36Heterotopia (HP:0002282)2.68220875
37Transitional cell carcinoma of the bladder (HP:0006740)2.64876985
38Popliteal pterygium (HP:0009756)2.58626083
39Bladder carcinoma (HP:0002862)2.56690857
40Bladder neoplasm (HP:0009725)2.56690857
41Osteomalacia (HP:0002749)2.55865790
42Diastasis recti (HP:0001540)2.53099621
43Abnormality of the fingertips (HP:0001211)2.48244229
44Abnormality of the proximal phalanges of the hand (HP:0009834)2.46045818
45Muscle fiber splitting (HP:0003555)2.42536847
46Abnormality of chromosome segregation (HP:0002916)2.40465583
47Abnormality of the labia (HP:0000058)2.38767954
48Disinhibition (HP:0000734)2.33178130
49Areflexia of lower limbs (HP:0002522)2.31952893
50Arterial tortuosity (HP:0005116)2.30871646
51Short tibia (HP:0005736)2.30727106
52Oligodactyly (HP:0012165)2.30660536
53Volvulus (HP:0002580)2.30557329
54Aplasia/Hypoplasia of the tibia (HP:0005772)2.29514190
55Colon cancer (HP:0003003)2.26747639
56EMG: myopathic abnormalities (HP:0003458)2.25145654
57Supernumerary spleens (HP:0009799)2.19531012
58Truncal obesity (HP:0001956)2.19524563
59Acute myeloid leukemia (HP:0004808)2.19361111
60Overlapping toe (HP:0001845)2.17984696
61Aplasia/Hypoplasia of the sternum (HP:0006714)2.16101552
62Patellar aplasia (HP:0006443)2.15586399
63Chin dimple (HP:0010751)2.14058227
64Vertebral arch anomaly (HP:0008438)2.13849002
65Spontaneous abortion (HP:0005268)2.13000627
66Gastrointestinal carcinoma (HP:0002672)2.12409077
67Malignant gastrointestinal tract tumors (HP:0006749)2.12409077
68Enlarged penis (HP:0000040)2.11520759
69Aqueductal stenosis (HP:0002410)2.10375578
70Microglossia (HP:0000171)2.10320918
71Neoplasm of the oral cavity (HP:0100649)2.06604516
72Breast aplasia (HP:0100783)2.05532169
73Biliary tract neoplasm (HP:0100574)2.03615797
74Hyperglycemia (HP:0003074)2.03292090
75Generalized hypopigmentation of hair (HP:0011358)2.02750962
76Fetal akinesia sequence (HP:0001989)2.01558422
77Metaphyseal dysplasia (HP:0100255)2.01259125
78Dysmetric saccades (HP:0000641)1.99497548
79Leiomyosarcoma (HP:0100243)1.99154386
80Uterine leiomyosarcoma (HP:0002891)1.99154386
81Absent radius (HP:0003974)1.99012335
82Frequent falls (HP:0002359)1.98652795
83Aplasia/Hypoplasia of the breasts (HP:0010311)1.97934459
84Impaired vibration sensation in the lower limbs (HP:0002166)1.97196887
85Aplasia/Hypoplasia of the earlobes (HP:0009906)1.96955208
86Hypoplastic female external genitalia (HP:0012815)1.95712129
87Absent forearm bone (HP:0003953)1.94095398
88Aplasia involving forearm bones (HP:0009822)1.94095398
89Uterine neoplasm (HP:0010784)1.93427436
90Rhabdomyosarcoma (HP:0002859)1.93152205
91Limb-girdle muscle weakness (HP:0003325)1.93144062
92Curly hair (HP:0002212)1.91362561
93Abnormality of chromosome stability (HP:0003220)1.90768866
94Labial hypoplasia (HP:0000066)1.89860604
95Aplasia/Hypoplasia of the patella (HP:0006498)1.89234833
96Inappropriate behavior (HP:0000719)1.88696708
97Skin pits (HP:0100276)1.88024424
98Broad thumb (HP:0011304)1.87189972
99Round ear (HP:0100830)1.86905272
100Short 1st metacarpal (HP:0010034)1.86212305
101Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.86212305
102Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.85484626
103Pelvic girdle muscle weakness (HP:0003749)1.85480560
104Cystic hygroma (HP:0000476)1.84612031
105Breast carcinoma (HP:0003002)1.84099650
106Poor eye contact (HP:0000817)1.83974579
107Limited hip movement (HP:0008800)1.82957731
108Abnormal biliary tract morphology (HP:0012440)1.82365180
109Azoospermia (HP:0000027)1.82228935
110Hypochromic microcytic anemia (HP:0004840)1.81238404
111Clitoromegaly (HP:0000057)1.80988282
112Hepatoblastoma (HP:0002884)1.80687119
113Difficulty running (HP:0009046)1.80437345
114Cafe-au-lait spot (HP:0000957)1.80141543
115Neck muscle weakness (HP:0000467)1.79773418
116Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.79534200
117Degeneration of the lateral corticospinal tracts (HP:0002314)1.79534200
118Sparse lateral eyebrow (HP:0005338)1.79440580
119Abnormality of the ischium (HP:0003174)1.79387719
120Aplasia involving bones of the upper limbs (HP:0009823)1.78982998
121Aplasia of the phalanges of the hand (HP:0009802)1.78982998
122Aplasia involving bones of the extremities (HP:0009825)1.78982998
123Myoglobinuria (HP:0002913)1.78797285
124Short chin (HP:0000331)1.77938341
125Abnormality of the clitoris (HP:0000056)1.76911627
126Absent phalangeal crease (HP:0006109)1.76797265
127Deep venous thrombosis (HP:0002625)1.76732519
128Abnormal spermatogenesis (HP:0008669)1.76148496
129Abnormality of the musculature of the pelvis (HP:0001469)1.75179563
130Abnormality of the hip-girdle musculature (HP:0001445)1.75179563
131Vascular tortuosity (HP:0004948)1.75106764
132Abnormality of alanine metabolism (HP:0010916)1.74168060
133Hyperalaninemia (HP:0003348)1.74168060
134Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.74168060
135Nephroblastoma (Wilms tumor) (HP:0002667)1.73817294
136Hyperinsulinemic hypoglycemia (HP:0000825)1.73316266
137Chromsome breakage (HP:0040012)1.73246602
138Hypoglycemic coma (HP:0001325)1.73197864
139Protruding tongue (HP:0010808)1.72701806
140Malignant hyperthermia (HP:0002047)1.72509836
141Subacute progressive viral hepatitis (HP:0006572)1.70625136
142Maternal diabetes (HP:0009800)1.69144169
143Abnormality of the corticospinal tract (HP:0002492)1.68583666
144Neoplasm of the small intestine (HP:0100833)1.68571453
145Adrenal hypoplasia (HP:0000835)1.68022007
146Hyperkalemia (HP:0002153)1.67087226
147Limb dystonia (HP:0002451)1.66041862
148Myotonia (HP:0002486)1.65414877
149Increased mean platelet volume (HP:0011877)1.65098125
150Neoplasm of the thyroid gland (HP:0100031)1.64745547
151Microtia (HP:0008551)1.62526296
152Broad alveolar ridges (HP:0000187)1.61951118
153Abnormal finger flexion creases (HP:0006143)1.61866194
154Deep palmar crease (HP:0006191)1.61708905
155Hip contracture (HP:0003273)1.61686557
156Sudden death (HP:0001699)1.61568385
157Rib fusion (HP:0000902)1.61170868
158Esophageal atresia (HP:0002032)1.61143728
159Short middle phalanx of the 5th finger (HP:0004220)1.61023562
160Scotoma (HP:0000575)1.60621221
161Non-midline cleft lip (HP:0100335)1.59232859
162Dyskinesia (HP:0100660)1.59175182
163Gonadotropin excess (HP:0000837)1.58755579
164Rectal prolapse (HP:0002035)1.57817719
165Abdominal situs inversus (HP:0003363)1.57021009
166Abnormality of abdominal situs (HP:0011620)1.57021009
167Type II lissencephaly (HP:0007260)1.56648689
168Hypoglycemic seizures (HP:0002173)1.56097573
169Embryonal renal neoplasm (HP:0011794)1.56037870
170Atonic seizures (HP:0010819)1.55723706
171EMG: neuropathic changes (HP:0003445)1.55259467
172Cubitus valgus (HP:0002967)1.55097885
173Febrile seizures (HP:0002373)1.54881775
174Hip dysplasia (HP:0001385)1.54499469
175Heart block (HP:0012722)1.54078061
176Broad-based gait (HP:0002136)1.53861562
177Hypoplastic ischia (HP:0003175)1.53119220
178Midline defect of the nose (HP:0004122)1.52044958

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS16.12768530
2OBSCN4.23496013
3LATS24.04683276
4STK38L3.66893847
5MAP3K63.01740003
6ACVR1B2.79786706
7KSR22.71067863
8MAP3K92.68995398
9CDC72.59035490
10STK32.51146730
11PHKG22.44563054
12PHKG12.44563054
13ERBB42.38947970
14MAP3K122.30513969
15TAF12.27964275
16FRK2.23317202
17ERBB32.18971762
18CDK122.17786306
19BMPR1B2.06252118
20MELK2.02027855
21PLK42.00435661
22TAOK31.94205854
23FGFR21.85507532
24MAP3K41.79725556
25TIE11.77894785
26RAF11.73903125
27MOS1.63477155
28KSR11.61470236
29TAOK11.61159071
30TTN1.57862322
31TTK1.55729212
32TYRO31.53978191
33NEK91.51135058
34AKT31.51019258
35TGFBR11.48979471
36CDK91.44013179
37PRKD31.41675198
38EIF2AK11.35025988
39CHEK21.31377043
40STK381.24884035
41MAP3K131.22598623
42PAK61.22370345
43CASK1.20643050
44RIPK41.13013054
45PLK31.11189035
46NEK11.06913775
47MAP3K101.06079785
48NLK1.02298510
49MET1.02032227
50MAP3K21.01531495
51STK101.01059779
52NUAK10.99702548
53MKNK20.99383293
54PIK3CG0.99240146
55EEF2K0.98996724
56RET0.97240169
57NEK20.96705056
58PIK3CA0.96622821
59WNK10.95319762
60BMPR20.94944649
61PLK10.94943011
62PDGFRB0.93093189
63TRPM70.92051593
64MAP2K40.87678042
65TSSK60.85267391
66STK110.84055567
67SRPK10.83646878
68WEE10.82179950
69WNK30.80565877
70ATM0.80437406
71RPS6KB10.78372445
72CSNK1G10.78349199
73BRAF0.76028245
74CDK80.76025956
75MAP3K80.75415251
76PINK10.74713353
77TRIM280.74647650
78CHEK10.74424898
79DYRK20.74262390
80MAP2K70.73716059
81ZAK0.72655372
82YES10.70319605
83DMPK0.69134450
84ARAF0.68340429
85PKN20.67020750
86BRSK20.66875514
87BCR0.66332268
88ABL20.63603352
89PRKAA10.63156088
90DYRK30.62705908
91CSNK1G20.62650117
92MAP3K50.62423991
93STK240.61744532
94FGFR10.60064247
95CDK30.58536318
96FGFR30.57093748
97PASK0.56080942
98NTRK20.54930976
99CDK60.53981847
100EIF2AK20.53920543
101MAPK100.53745501
102CAMK2D0.53736492
103AURKB0.53321819
104CSNK1D0.53070783
105ABL10.50674441
106MST40.50635244
107PRKAA20.50377983
108CDK40.50093764
109HIPK20.47918381
110MAP3K70.47425235
111MARK30.47288352
112CDK20.45173475
113CDK10.44925553
114CDK190.44717983
115NEK60.44578880
116PNCK0.43586583
117CAMKK20.43111954
118CSNK1A1L0.43048887
119NTRK30.42107779
120CDK70.41525289
121MAP2K10.41160328
122CAMK2A0.40987428
123DYRK1B0.40539878
124PRKD20.40455734
125PDK10.39546316
126PLK20.39021094
127PAK30.38666722
128EIF2AK30.38594356
129CSNK1G30.37262183
130STK390.36700435
131AKT20.36634575
132JAK20.35814836
133BRD40.35574556
134OXSR10.35178647
135RPS6KB20.35060508
136PDGFRA0.34120495
137MAPK130.31249225
138CSNK1E0.30777100
139MUSK0.30632391
140CAMK1D0.30246399
141ALK0.30098365
142MAPKAPK30.29215738
143SGK20.29155918
144MKNK10.28323743
145CAMK1G0.27592252
146SGK10.27582499

Predicted pathways (KEGG)

RankGene SetZ-score
1Dorso-ventral axis formation_Homo sapiens_hsa043202.79664240
2Nitrogen metabolism_Homo sapiens_hsa009102.61357470
3Cell cycle_Homo sapiens_hsa041102.46512298
4Progesterone-mediated oocyte maturation_Homo sapiens_hsa049142.29353208
5Basal transcription factors_Homo sapiens_hsa030222.24046047
6Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.17990122
7RNA degradation_Homo sapiens_hsa030182.13386835
8Oocyte meiosis_Homo sapiens_hsa041142.13242496
9TGF-beta signaling pathway_Homo sapiens_hsa043502.12420991
10Pancreatic cancer_Homo sapiens_hsa052122.09934019
11Renal cell carcinoma_Homo sapiens_hsa052112.07977265
12mRNA surveillance pathway_Homo sapiens_hsa030151.91751495
13MicroRNAs in cancer_Homo sapiens_hsa052061.90847952
14mTOR signaling pathway_Homo sapiens_hsa041501.90740709
15Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.84362982
16Endometrial cancer_Homo sapiens_hsa052131.82070943
17Colorectal cancer_Homo sapiens_hsa052101.79676587
18Circadian rhythm_Homo sapiens_hsa047101.77396177
19Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.66159404
20Ovarian steroidogenesis_Homo sapiens_hsa049131.64347352
21Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.61560493
22Hippo signaling pathway_Homo sapiens_hsa043901.55574690
23RNA transport_Homo sapiens_hsa030131.54558677
24Choline metabolism in cancer_Homo sapiens_hsa052311.53585898
25Regulation of autophagy_Homo sapiens_hsa041401.53521896
26Thyroid cancer_Homo sapiens_hsa052161.52458230
27Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.45599720
28ErbB signaling pathway_Homo sapiens_hsa040121.44744005
29Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.43089413
30Prostate cancer_Homo sapiens_hsa052151.41680246
31Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.40300378
32Propanoate metabolism_Homo sapiens_hsa006401.37739514
33Prolactin signaling pathway_Homo sapiens_hsa049171.37059272
34Non-small cell lung cancer_Homo sapiens_hsa052231.36116247
35Adherens junction_Homo sapiens_hsa045201.32292903
36Arginine biosynthesis_Homo sapiens_hsa002201.30640827
37Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.30153133
38Chronic myeloid leukemia_Homo sapiens_hsa052201.27182600
39Vitamin B6 metabolism_Homo sapiens_hsa007501.26845274
40Caffeine metabolism_Homo sapiens_hsa002321.24487710
41Glioma_Homo sapiens_hsa052141.24363207
42FoxO signaling pathway_Homo sapiens_hsa040681.23904616
43Dilated cardiomyopathy_Homo sapiens_hsa054141.21660913
44GnRH signaling pathway_Homo sapiens_hsa049121.19754019
45VEGF signaling pathway_Homo sapiens_hsa043701.17988634
46Long-term potentiation_Homo sapiens_hsa047201.14741447
47Estrogen signaling pathway_Homo sapiens_hsa049151.14663680
48p53 signaling pathway_Homo sapiens_hsa041151.13174453
49Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.09694646
50Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.09104761
51Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.05965100
52Lysine degradation_Homo sapiens_hsa003101.04763311
53Small cell lung cancer_Homo sapiens_hsa052221.03566119
54Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.03151401
55Long-term depression_Homo sapiens_hsa047301.02009800
56Maturity onset diabetes of the young_Homo sapiens_hsa049501.00557684
57Longevity regulating pathway - mammal_Homo sapiens_hsa042110.98169637
58Wnt signaling pathway_Homo sapiens_hsa043100.92755155
59Nicotine addiction_Homo sapiens_hsa050330.92144556
60Phototransduction_Homo sapiens_hsa047440.91425841
61Ether lipid metabolism_Homo sapiens_hsa005650.90842578
62Ras signaling pathway_Homo sapiens_hsa040140.90433929
63Type II diabetes mellitus_Homo sapiens_hsa049300.87469601
64Renin secretion_Homo sapiens_hsa049240.86690061
65Thyroid hormone signaling pathway_Homo sapiens_hsa049190.86450382
66AMPK signaling pathway_Homo sapiens_hsa041520.86334318
67MAPK signaling pathway_Homo sapiens_hsa040100.86288738
68Calcium signaling pathway_Homo sapiens_hsa040200.85998777
69Melanoma_Homo sapiens_hsa052180.85930065
70Protein export_Homo sapiens_hsa030600.83855687
71Linoleic acid metabolism_Homo sapiens_hsa005910.83626735
72Insulin resistance_Homo sapiens_hsa049310.83412677
73Fanconi anemia pathway_Homo sapiens_hsa034600.82903145
74Cysteine and methionine metabolism_Homo sapiens_hsa002700.82330836
75Phosphatidylinositol signaling system_Homo sapiens_hsa040700.81432282
76Phospholipase D signaling pathway_Homo sapiens_hsa040720.81256676
77Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.80835111
78Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.79511572
79Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.79288471
80Sphingolipid signaling pathway_Homo sapiens_hsa040710.77843035
81Inositol phosphate metabolism_Homo sapiens_hsa005620.75911819
82GABAergic synapse_Homo sapiens_hsa047270.75736942
83Insulin signaling pathway_Homo sapiens_hsa049100.75240432
84Tight junction_Homo sapiens_hsa045300.74841795
85Insulin secretion_Homo sapiens_hsa049110.74832233
86Gap junction_Homo sapiens_hsa045400.74155180
87Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.73718024
88alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.73522586
89Serotonergic synapse_Homo sapiens_hsa047260.72140497
90Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.71317853
91Glucagon signaling pathway_Homo sapiens_hsa049220.70160549
92Cholinergic synapse_Homo sapiens_hsa047250.69852725
93Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.69815680
94Hepatitis B_Homo sapiens_hsa051610.69596334
95Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.68260332
96Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.68152253
97Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.67908943
98Circadian entrainment_Homo sapiens_hsa047130.66457767
99ABC transporters_Homo sapiens_hsa020100.65962347
100Proteoglycans in cancer_Homo sapiens_hsa052050.64596294
101Basal cell carcinoma_Homo sapiens_hsa052170.62802470
1022-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.59799285
103Non-homologous end-joining_Homo sapiens_hsa034500.59622829
104Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.59308117
105Melanogenesis_Homo sapiens_hsa049160.58926674
106Glutamatergic synapse_Homo sapiens_hsa047240.58911608
107Neurotrophin signaling pathway_Homo sapiens_hsa047220.58393053
108Nucleotide excision repair_Homo sapiens_hsa034200.56387864
109cGMP-PKG signaling pathway_Homo sapiens_hsa040220.56162454
110Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.55578934
111Pathways in cancer_Homo sapiens_hsa052000.55518119
112Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.54208144
113Platelet activation_Homo sapiens_hsa046110.54078690
114Amoebiasis_Homo sapiens_hsa051460.53500950
115Focal adhesion_Homo sapiens_hsa045100.52968518
116Central carbon metabolism in cancer_Homo sapiens_hsa052300.52377973
117cAMP signaling pathway_Homo sapiens_hsa040240.49327958
118HTLV-I infection_Homo sapiens_hsa051660.49110427
119Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.48999383
120Regulation of actin cytoskeleton_Homo sapiens_hsa048100.48718443
121Taste transduction_Homo sapiens_hsa047420.47987592
122Fatty acid biosynthesis_Homo sapiens_hsa000610.46825323
123Dopaminergic synapse_Homo sapiens_hsa047280.46743490
124T cell receptor signaling pathway_Homo sapiens_hsa046600.46739326
125Rap1 signaling pathway_Homo sapiens_hsa040150.46431866
126Oxytocin signaling pathway_Homo sapiens_hsa049210.45950247
127Homologous recombination_Homo sapiens_hsa034400.44493802
128Selenocompound metabolism_Homo sapiens_hsa004500.44378448
129RNA polymerase_Homo sapiens_hsa030200.44021298
130Vascular smooth muscle contraction_Homo sapiens_hsa042700.40371828
131Amphetamine addiction_Homo sapiens_hsa050310.40366666
132Axon guidance_Homo sapiens_hsa043600.39572522
133Hedgehog signaling pathway_Homo sapiens_hsa043400.38424640
134Acute myeloid leukemia_Homo sapiens_hsa052210.37720756
135Toxoplasmosis_Homo sapiens_hsa051450.37192618
136Sphingolipid metabolism_Homo sapiens_hsa006000.36342468

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