NAA35

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)4.62339517
2metaphase plate congression (GO:0051310)4.07274087
3nuclear pore organization (GO:0006999)3.96804789
4DNA double-strand break processing (GO:0000729)3.88032725
5piRNA metabolic process (GO:0034587)3.82591726
6attachment of spindle microtubules to kinetochore (GO:0008608)3.72211590
7synapsis (GO:0007129)3.60700667
8DNA replication checkpoint (GO:0000076)3.55038126
9resolution of meiotic recombination intermediates (GO:0000712)3.51752318
10cullin deneddylation (GO:0010388)3.50085736
11mitotic sister chromatid segregation (GO:0000070)3.49500784
12replication fork processing (GO:0031297)3.48838684
13purine nucleobase biosynthetic process (GO:0009113)3.46223001
14regulation of meiosis I (GO:0060631)3.43851449
15protein deneddylation (GO:0000338)3.38764375
16DNA replication-dependent nucleosome assembly (GO:0006335)3.37685170
17DNA replication-dependent nucleosome organization (GO:0034723)3.37685170
18establishment of chromosome localization (GO:0051303)3.32485471
19mitotic nuclear envelope disassembly (GO:0007077)3.32100500
20nuclear pore complex assembly (GO:0051292)3.31084681
21nucleobase biosynthetic process (GO:0046112)3.30408918
22chromatin remodeling at centromere (GO:0031055)3.28875098
23kinetochore organization (GO:0051383)3.26891252
24microtubule depolymerization (GO:0007019)3.24831438
25CENP-A containing nucleosome assembly (GO:0034080)3.24323663
26mitotic spindle checkpoint (GO:0071174)3.23744818
27kinetochore assembly (GO:0051382)3.23117384
28negative regulation of chromosome segregation (GO:0051985)3.22347769
29negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.21874233
30DNA methylation involved in gamete generation (GO:0043046)3.19731539
31negative regulation of mitotic sister chromatid separation (GO:2000816)3.19731051
32negative regulation of mitotic sister chromatid segregation (GO:0033048)3.19731051
33negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.19731051
34negative regulation of sister chromatid segregation (GO:0033046)3.19731051
35DNA replication initiation (GO:0006270)3.19162616
36spindle checkpoint (GO:0031577)3.18350038
37mitotic spindle assembly checkpoint (GO:0007094)3.15360226
38DNA replication-independent nucleosome assembly (GO:0006336)3.13885608
39DNA replication-independent nucleosome organization (GO:0034724)3.13885608
407-methylguanosine mRNA capping (GO:0006370)3.10608155
41maturation of 5.8S rRNA (GO:0000460)3.10434729
42spindle assembly checkpoint (GO:0071173)3.08176821
43histone arginine methylation (GO:0034969)3.05745155
44nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.05223212
45nuclear envelope disassembly (GO:0051081)3.04808135
46membrane disassembly (GO:0030397)3.04808135
47exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.03028499
48histone exchange (GO:0043486)3.02345591
49RNA capping (GO:0036260)3.02177953
507-methylguanosine RNA capping (GO:0009452)3.02177953
51sister chromatid segregation (GO:0000819)3.00680659
52mitotic chromosome condensation (GO:0007076)3.00577809
53regulation of DNA endoreduplication (GO:0032875)3.00535295
54regulation of mitotic spindle checkpoint (GO:1903504)2.99248830
55regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.99248830
56formation of translation preinitiation complex (GO:0001731)2.97998395
57regulation of centriole replication (GO:0046599)2.97963670
58spliceosomal snRNP assembly (GO:0000387)2.97188025
59regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.97110118
60establishment of protein localization to mitochondrial membrane (GO:0090151)2.95917323
61mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.95338252
62regulation of mitotic metaphase/anaphase transition (GO:0030071)2.94889441
63regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.92844080
64regulation of double-strand break repair via homologous recombination (GO:0010569)2.92802771
65intraciliary transport (GO:0042073)2.91086423
66spliceosomal complex assembly (GO:0000245)2.89665674
67regulation of chromosome segregation (GO:0051983)2.89423831
68negative regulation of DNA-dependent DNA replication (GO:2000104)2.88552346
69meiotic chromosome segregation (GO:0045132)2.88301060
70non-recombinational repair (GO:0000726)2.88047959
71double-strand break repair via nonhomologous end joining (GO:0006303)2.88047959
72regulation of mitotic sister chromatid separation (GO:0010965)2.86423518
73regulation of mitotic sister chromatid segregation (GO:0033047)2.86423518
74regulation of sister chromatid segregation (GO:0033045)2.86423518
75paraxial mesoderm development (GO:0048339)2.86221749
76ribosome biogenesis (GO:0042254)2.85872810
77centriole replication (GO:0007099)2.85846540
78termination of RNA polymerase III transcription (GO:0006386)2.82754633
79transcription elongation from RNA polymerase III promoter (GO:0006385)2.82754633
80histone H2A acetylation (GO:0043968)2.79119411
81IMP biosynthetic process (GO:0006188)2.78795274
82histone mRNA metabolic process (GO:0008334)2.78412022
83DNA damage response, detection of DNA damage (GO:0042769)2.78068832
84protein localization to kinetochore (GO:0034501)2.77139571
85postreplication repair (GO:0006301)2.76926573
86synaptonemal complex assembly (GO:0007130)2.76767703
87maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.76446453
88anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.76417380
89proteasome assembly (GO:0043248)2.75098415
90negative regulation of meiosis (GO:0045835)2.74356533
91transcription-coupled nucleotide-excision repair (GO:0006283)2.74139839
92intra-S DNA damage checkpoint (GO:0031573)2.73160496
93mitotic sister chromatid cohesion (GO:0007064)2.72917347
94synaptonemal complex organization (GO:0070193)2.71837763
95regulation of centrosome cycle (GO:0046605)2.71632429
96viral mRNA export from host cell nucleus (GO:0046784)2.71493016
97nucleotide-excision repair, DNA gap filling (GO:0006297)2.70245238
98protein localization to chromosome, centromeric region (GO:0071459)2.70016405
99male meiosis (GO:0007140)2.69340888
100establishment of integrated proviral latency (GO:0075713)2.68251233
101DNA strand elongation involved in DNA replication (GO:0006271)2.68093530
102DNA strand elongation (GO:0022616)2.67951401
103ribosome assembly (GO:0042255)2.67890571
104telomere maintenance via semi-conservative replication (GO:0032201)2.66743982
105DNA ligation (GO:0006266)2.65973564
106negative regulation of mitosis (GO:0045839)2.65665626
107DNA strand renaturation (GO:0000733)2.65267655
108meiotic nuclear division (GO:0007126)2.63544767
109negative regulation of nuclear division (GO:0051784)2.63418529
110protein K6-linked ubiquitination (GO:0085020)2.62857983
111chromosome segregation (GO:0007059)2.62838778
112tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.62816220
113RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.62816220
114RNA splicing, via transesterification reactions (GO:0000375)2.62428855
115peptidyl-arginine omega-N-methylation (GO:0035247)2.62264247
116regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.61463692
117ATP-dependent chromatin remodeling (GO:0043044)2.60306384
118mRNA splicing, via spliceosome (GO:0000398)2.60208261
119RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.60208261
120regulation of nuclear cell cycle DNA replication (GO:0033262)2.59615537
121mismatch repair (GO:0006298)2.59117465
122regulation of helicase activity (GO:0051095)2.58864922
123telomere maintenance via telomerase (GO:0007004)2.58468492
124DNA catabolic process, exonucleolytic (GO:0000738)2.58463413
125mRNA transport (GO:0051028)2.58379708
126somatic hypermutation of immunoglobulin genes (GO:0016446)2.57871020
127peptidyl-histidine modification (GO:0018202)2.55701331
128negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.54939246
129meiotic cell cycle (GO:0051321)2.54175007
130positive regulation of histone H3-K4 methylation (GO:0051571)2.54086895
131recombinational repair (GO:0000725)2.52038094
132mitotic recombination (GO:0006312)2.51081869
133telomere maintenance via recombination (GO:0000722)2.49260813
134positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.48847034
135sister chromatid cohesion (GO:0007062)2.48791010
136double-strand break repair via homologous recombination (GO:0000724)2.48509233
137negative regulation of DNA recombination (GO:0045910)2.46954374
138RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.45359368
139somatic diversification of immune receptors via somatic mutation (GO:0002566)2.44949110
140reciprocal DNA recombination (GO:0035825)2.44775034
141reciprocal meiotic recombination (GO:0007131)2.44775034
142protein localization to chromosome (GO:0034502)2.44012068
143chromosome organization involved in meiosis (GO:0070192)2.41936430
144translesion synthesis (GO:0019985)2.41836247
145rRNA modification (GO:0000154)2.39863342
146chaperone-mediated protein transport (GO:0072321)2.39431481

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.15151542
2RBPJ_22232070_ChIP-Seq_NCS_Mouse3.92211126
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.51215744
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.39620050
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.18708109
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.11940801
7MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.96270155
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.88906962
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.80403886
10* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.76237187
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.60666634
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.58944714
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.56225929
14SALL1_21062744_ChIP-ChIP_HESCs_Human2.56184074
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.51650410
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.50834612
17ETS1_20019798_ChIP-Seq_JURKAT_Human2.46277419
18ZNF274_21170338_ChIP-Seq_K562_Hela2.46147336
19E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.35464468
20TP63_19390658_ChIP-ChIP_HaCaT_Human2.34168241
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.32582779
22CREB1_15753290_ChIP-ChIP_HEK293T_Human2.32329817
23NELFA_20434984_ChIP-Seq_ESCs_Mouse2.23502241
24MYC_18358816_ChIP-ChIP_MESCs_Mouse2.21399632
25MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.15937667
26YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.14940847
27POU3F2_20337985_ChIP-ChIP_501MEL_Human2.12949591
28PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.05850899
29TAF15_26573619_Chip-Seq_HEK293_Human2.02800129
30MYCN_18555785_ChIP-Seq_MESCs_Mouse1.98781933
31IGF1R_20145208_ChIP-Seq_DFB_Human1.96230322
32AR_21909140_ChIP-Seq_LNCAP_Human1.92587346
33VDR_22108803_ChIP-Seq_LS180_Human1.88943023
34THAP11_20581084_ChIP-Seq_MESCs_Mouse1.88592394
35HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.88138370
36POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.86703503
37* DCP1A_22483619_ChIP-Seq_HELA_Human1.85514363
38MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.83625828
39XRN2_22483619_ChIP-Seq_HELA_Human1.82714669
40SOX2_18555785_ChIP-Seq_MESCs_Mouse1.79022795
41CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.75125400
42E2F1_18555785_ChIP-Seq_MESCs_Mouse1.73467470
43* VDR_23849224_ChIP-Seq_CD4+_Human1.69899038
44EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.68031457
45ZFP57_27257070_Chip-Seq_ESCs_Mouse1.65154058
46FLI1_27457419_Chip-Seq_LIVER_Mouse1.64161874
47YY1_21170310_ChIP-Seq_MESCs_Mouse1.61886168
48E2F1_21310950_ChIP-Seq_MCF-7_Human1.61614193
49* TTF2_22483619_ChIP-Seq_HELA_Human1.59431516
50P300_19829295_ChIP-Seq_ESCs_Human1.59147722
51GABP_19822575_ChIP-Seq_HepG2_Human1.58917245
52DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.57586071
53POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.57219917
54ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.53761099
55POU5F1_16153702_ChIP-ChIP_HESCs_Human1.53623623
56NANOG_18555785_ChIP-Seq_MESCs_Mouse1.49322828
57CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.48635689
58NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.47882789
59FOXP3_21729870_ChIP-Seq_TREG_Human1.47824281
60NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.46640539
61NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.44688547
62KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.39980073
63KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.39980073
64KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.39980073
65GBX2_23144817_ChIP-Seq_PC3_Human1.39870866
66SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.37940067
67FUS_26573619_Chip-Seq_HEK293_Human1.35943027
68PADI4_21655091_ChIP-ChIP_MCF-7_Human1.35178044
69FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.31955331
70SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.29677772
71PCGF2_27294783_Chip-Seq_ESCs_Mouse1.29354889
72* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.28487187
73NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.28476470
74ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.26397493
75ZFX_18555785_ChIP-Seq_MESCs_Mouse1.25492451
76NANOG_21062744_ChIP-ChIP_HESCs_Human1.24002066
77PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.23680862
78HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.23394391
79SOX2_16153702_ChIP-ChIP_HESCs_Human1.22615047
80CTBP1_25329375_ChIP-Seq_LNCAP_Human1.22209574
81EWS_26573619_Chip-Seq_HEK293_Human1.21423951
82NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.21314747
83* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.20152279
84TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19243366
85GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18936587
86KDM5A_27292631_Chip-Seq_BREAST_Human1.18022859
87SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.17905301
88RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.16807163
89MYC_18940864_ChIP-ChIP_HL60_Human1.16749808
90PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.15944856
91AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.15683867
92GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.13539681
93POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.12927892
94CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.12919102
95SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.12904395
96EZH2_22144423_ChIP-Seq_EOC_Human1.12790742
97ELK1_19687146_ChIP-ChIP_HELA_Human1.12251805
98IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.11862120
99CBP_20019798_ChIP-Seq_JUKART_Human1.11862120
100* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11198286
101HOXB4_20404135_ChIP-ChIP_EML_Mouse1.10675004
102CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.10426904
103UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.09618879
104KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.09142129
105TCF3_18692474_ChIP-Seq_MESCs_Mouse1.08380132
106ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.08297994
107CIITA_25753668_ChIP-Seq_RAJI_Human1.08014196
108MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.05324057
109ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.05221400
110ER_23166858_ChIP-Seq_MCF-7_Human1.04764860
111TCF3_18692474_ChIP-Seq_MEFs_Mouse1.03512212
112MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.03182317
113SMAD4_21799915_ChIP-Seq_A2780_Human1.02575716
114SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.02557103
115SRF_21415370_ChIP-Seq_HL-1_Mouse1.00700919
116RNF2_27304074_Chip-Seq_NSC_Mouse0.99634377
117NANOG_16153702_ChIP-ChIP_HESCs_Human0.97105748
118OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.95975769
119TOP2B_26459242_ChIP-Seq_MCF-7_Human0.94963562
120TP53_22573176_ChIP-Seq_HFKS_Human0.93444357
121IRF1_19129219_ChIP-ChIP_H3396_Human0.93306171
122EZH2_27294783_Chip-Seq_NPCs_Mouse0.93010897
123HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.92155607
124CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.91247819
125SOX17_20123909_ChIP-Seq_XEN_Mouse0.90817651
126POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.90672174
127STAT3_23295773_ChIP-Seq_U87_Human0.90451142
128EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.89550639
129FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.88247009
130BMI1_23680149_ChIP-Seq_NPCS_Mouse0.87483186
131NOTCH1_21737748_ChIP-Seq_TLL_Human0.85588233
132E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.81583144
133NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.80251761
134GATA1_26923725_Chip-Seq_HPCs_Mouse0.80099935
135TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.79224601
136CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.78646825

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.57639921
2MP0003123_paternal_imprinting3.42768234
3MP0008877_abnormal_DNA_methylation3.30437740
4MP0010094_abnormal_chromosome_stability2.98859556
5MP0003111_abnormal_nucleus_morphology2.88901929
6MP0004957_abnormal_blastocyst_morpholog2.82494291
7MP0008058_abnormal_DNA_repair2.65221759
8MP0003121_genomic_imprinting2.62164618
9MP0006292_abnormal_olfactory_placode2.60317703
10MP0008057_abnormal_DNA_replication2.51938018
11MP0003077_abnormal_cell_cycle2.51244134
12MP0009697_abnormal_copulation2.26624469
13MP0003718_maternal_effect2.22887331
14MP0008932_abnormal_embryonic_tissue2.12733743
15MP0002653_abnormal_ependyma_morphology2.09303451
16MP0003315_abnormal_perineum_morphology2.08597670
17MP0003890_abnormal_embryonic-extraembry1.99965798
18MP0001188_hyperpigmentation1.86987850
19MP0003122_maternal_imprinting1.81518615
20MP0001529_abnormal_vocalization1.73161172
21MP0003119_abnormal_digestive_system1.72745144
22MP0003787_abnormal_imprinting1.69594701
23MP0002210_abnormal_sex_determination1.68559807
24MP0002102_abnormal_ear_morphology1.65082706
25MP0004133_heterotaxia1.57661613
26MP0003937_abnormal_limbs/digits/tail_de1.57189800
27MP0001730_embryonic_growth_arrest1.56963443
28MP0008007_abnormal_cellular_replicative1.52996539
29MP0003786_premature_aging1.51340728
30MP0003941_abnormal_skin_development1.47125429
31MP0005380_embryogenesis_phenotype1.45003852
32MP0001672_abnormal_embryogenesis/_devel1.45003852
33MP0000537_abnormal_urethra_morphology1.44317849
34MP0000350_abnormal_cell_proliferation1.43688736
35MP0008789_abnormal_olfactory_epithelium1.43588462
36MP0002085_abnormal_embryonic_tissue1.41198926
37MP0001929_abnormal_gametogenesis1.39749744
38MP0002084_abnormal_developmental_patter1.39688665
39MP0009053_abnormal_anal_canal1.37973350
40MP0001145_abnormal_male_reproductive1.36997962
41MP0004145_abnormal_muscle_electrophysio1.36473478
42MP0001984_abnormal_olfaction1.36144837
43MP0000647_abnormal_sebaceous_gland1.34234404
44MP0002751_abnormal_autonomic_nervous1.34222605
45MP0006072_abnormal_retinal_apoptosis1.32112012
46MP0001697_abnormal_embryo_size1.30139317
47MP0000049_abnormal_middle_ear1.27965249
48MP0000569_abnormal_digit_pigmentation1.27624437
49MP0004142_abnormal_muscle_tone1.27610313
50MP0000653_abnormal_sex_gland1.26990206
51MP0003984_embryonic_growth_retardation1.26970809
52MP0002088_abnormal_embryonic_growth/wei1.26918023
53MP0010030_abnormal_orbit_morphology1.22580920
54MP0002160_abnormal_reproductive_system1.21193073
55MP0002697_abnormal_eye_size1.19530138
56MP0000778_abnormal_nervous_system1.18083232
57MP0005394_taste/olfaction_phenotype1.17391333
58MP0005499_abnormal_olfactory_system1.17391333
59MP0004233_abnormal_muscle_weight1.17278730
60MP0003861_abnormal_nervous_system1.15745005
61MP0003136_yellow_coat_color1.13259034
62MP0003698_abnormal_male_reproductive1.12999050
63MP0010678_abnormal_skin_adnexa1.12948194
64MP0000427_abnormal_hair_cycle1.12313067
65MP0003755_abnormal_palate_morphology1.12313004
66MP0005187_abnormal_penis_morphology1.10833302
67MP0000383_abnormal_hair_follicle1.10431056
68MP0003567_abnormal_fetal_cardiomyocyte1.06795157
69MP0000566_synostosis1.06669958
70MP0003938_abnormal_ear_development1.06048175
71MP0002127_abnormal_cardiovascular_syste1.03629586
72MP0005367_renal/urinary_system_phenotyp1.03395273
73MP0000516_abnormal_urinary_system1.03395273
74MP0006276_abnormal_autonomic_nervous1.03274127
75MP0002938_white_spotting1.02470358
76MP0002080_prenatal_lethality1.01304913
77MP0005084_abnormal_gallbladder_morpholo1.00397777
78MP0006035_abnormal_mitochondrial_morpho0.99298091
79MP0005253_abnormal_eye_physiology0.97009843
80MP0001485_abnormal_pinna_reflex0.96855399
81MP0000631_abnormal_neuroendocrine_gland0.96816997
82MP0004197_abnormal_fetal_growth/weight/0.96815536
83MP0008995_early_reproductive_senescence0.96388956
84MP0005395_other_phenotype0.95325094
85MP0003385_abnormal_body_wall0.94964838
86MP0004084_abnormal_cardiac_muscle0.94948377
87MP0005551_abnormal_eye_electrophysiolog0.94690944
88MP0002282_abnormal_trachea_morphology0.94643545
89MP0001293_anophthalmia0.94147547
90MP0003221_abnormal_cardiomyocyte_apopto0.93098451
91MP0005391_vision/eye_phenotype0.92555357
92MP0002233_abnormal_nose_morphology0.92545418
93MP0001119_abnormal_female_reproductive0.89034127
94MP0002095_abnormal_skin_pigmentation0.88783650
95MP0002184_abnormal_innervation0.86387546
96MP0001346_abnormal_lacrimal_gland0.85613752
97MP0005389_reproductive_system_phenotype0.85037505
98MP0002086_abnormal_extraembryonic_tissu0.84939131
99MP0002161_abnormal_fertility/fecundity0.84767643
100MP0010234_abnormal_vibrissa_follicle0.84360580
101MP0003935_abnormal_craniofacial_develop0.84300788
102MP0003880_abnormal_central_pattern0.84244233
103MP0001286_abnormal_eye_development0.83524994
104MP0003942_abnormal_urinary_system0.82658947
105MP0003186_abnormal_redox_activity0.82389690
106MP0003137_abnormal_impulse_conducting0.81069586
107MP0002092_abnormal_eye_morphology0.80857890
108MP0002111_abnormal_tail_morphology0.80207761
109MP0002249_abnormal_larynx_morphology0.77502703
110MP0002234_abnormal_pharynx_morphology0.77333829
111MP0009703_decreased_birth_body0.76515009
112MP0000762_abnormal_tongue_morphology0.75763169
113MP0003699_abnormal_female_reproductive0.75642228
114MP0002928_abnormal_bile_duct0.75244765
115MP0002116_abnormal_craniofacial_bone0.75212498
116MP0002736_abnormal_nociception_after0.75164529
117MP0002152_abnormal_brain_morphology0.74736380
118MP0001324_abnormal_eye_pigmentation0.74313252
119MP0001299_abnormal_eye_distance/0.74244602
120MP0005248_abnormal_Harderian_gland0.73548902
121MP0004215_abnormal_myocardial_fiber0.72319671
122MP0003115_abnormal_respiratory_system0.72189308
123MP0003283_abnormal_digestive_organ0.71246828
124MP0002177_abnormal_outer_ear0.70888362
125MP0001905_abnormal_dopamine_level0.70379273
126MP0002638_abnormal_pupillary_reflex0.68170711
127MP0000026_abnormal_inner_ear0.67084444
128MP0005377_hearing/vestibular/ear_phenot0.65367275

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the labia minora (HP:0012880)3.96573424
2Birth length less than 3rd percentile (HP:0003561)3.83778369
3Abnormality of the anterior horn cell (HP:0006802)3.25676230
4Degeneration of anterior horn cells (HP:0002398)3.25676230
5Supernumerary spleens (HP:0009799)3.24292158
6Breast hypoplasia (HP:0003187)3.09370913
7Patellar aplasia (HP:0006443)3.06265343
8Aplasia/Hypoplasia of the patella (HP:0006498)2.88617675
9Absent radius (HP:0003974)2.86491550
10True hermaphroditism (HP:0010459)2.73335984
11Absent forearm bone (HP:0003953)2.70554765
12Aplasia involving forearm bones (HP:0009822)2.70554765
13Increased hepatocellular lipid droplets (HP:0006565)2.63780789
14Septo-optic dysplasia (HP:0100842)2.62468281
15Oligodactyly (hands) (HP:0001180)2.58347605
16Abnormality of midbrain morphology (HP:0002418)2.57558441
17Molar tooth sign on MRI (HP:0002419)2.57558441
18Lipid accumulation in hepatocytes (HP:0006561)2.57028049
19Chromosomal breakage induced by crosslinking agents (HP:0003221)2.56246565
20Nephronophthisis (HP:0000090)2.52712832
21Colon cancer (HP:0003003)2.48311197
22Congenital primary aphakia (HP:0007707)2.46301261
23Impulsivity (HP:0100710)2.42990240
24Gonadotropin excess (HP:0000837)2.42786269
25Genital tract atresia (HP:0001827)2.41672812
26Ependymoma (HP:0002888)2.40200588
27Chromsome breakage (HP:0040012)2.37641284
28Vaginal atresia (HP:0000148)2.35170234
29Nephrogenic diabetes insipidus (HP:0009806)2.34930220
30Cerebral hypomyelination (HP:0006808)2.32545469
31Acute encephalopathy (HP:0006846)2.32289903
32Nephroblastoma (Wilms tumor) (HP:0002667)2.31242147
33Abnormal lung lobation (HP:0002101)2.31061868
34Meckel diverticulum (HP:0002245)2.29285406
35Reticulocytopenia (HP:0001896)2.28832324
36Horseshoe kidney (HP:0000085)2.28295824
37Abnormality of the ileum (HP:0001549)2.24409945
38Abnormality of the preputium (HP:0100587)2.23163286
39Short tibia (HP:0005736)2.20430591
40Medulloblastoma (HP:0002885)2.20381727
41Shoulder girdle muscle weakness (HP:0003547)2.19997164
42Shawl scrotum (HP:0000049)2.19335166
43Double outlet right ventricle (HP:0001719)2.19175619
44Congenital malformation of the right heart (HP:0011723)2.19175619
45Aplasia/Hypoplasia of the tongue (HP:0010295)2.17192722
46Embryonal renal neoplasm (HP:0011794)2.17176110
47Atrophy/Degeneration involving motor neurons (HP:0007373)2.17171748
48Volvulus (HP:0002580)2.16791961
49Increased CSF lactate (HP:0002490)2.15393532
50Median cleft lip (HP:0000161)2.15086164
51Aplasia/Hypoplasia of the uvula (HP:0010293)2.15016299
52Aplasia/Hypoplasia of the tibia (HP:0005772)2.14662495
53Aplasia/Hypoplasia of the sternum (HP:0006714)2.13998907
54Acute necrotizing encephalopathy (HP:0006965)2.13300397
55Absent septum pellucidum (HP:0001331)2.12051423
56Hyperglycinemia (HP:0002154)2.11842032
57Absent thumb (HP:0009777)2.08754967
58Intestinal atresia (HP:0011100)2.08387993
59Abnormality of the renal medulla (HP:0100957)2.07466128
60Rectal fistula (HP:0100590)2.07075985
61Rectovaginal fistula (HP:0000143)2.07075985
62Methylmalonic acidemia (HP:0002912)2.05927744
63Small intestinal stenosis (HP:0012848)2.05735222
64Duodenal stenosis (HP:0100867)2.05735222
65Postaxial foot polydactyly (HP:0001830)2.04964400
66Abnormality of the septum pellucidum (HP:0007375)2.03845073
67Spinal muscular atrophy (HP:0007269)2.03769043
68Abnormal number of incisors (HP:0011064)2.01477208
69Carpal bone hypoplasia (HP:0001498)2.01375555
70Type II lissencephaly (HP:0007260)2.00127382
71Papillary thyroid carcinoma (HP:0002895)1.99052992
72Facial cleft (HP:0002006)1.98892821
73Mitochondrial inheritance (HP:0001427)1.96714930
74Facial hemangioma (HP:0000329)1.96495130
75Abnormality of the lower motor neuron (HP:0002366)1.94446901
76Aplasia/Hypoplasia involving the musculature (HP:0001460)1.93979712
77Postaxial hand polydactyly (HP:0001162)1.91442092
78Oligodactyly (HP:0012165)1.91219313
79Optic nerve hypoplasia (HP:0000609)1.89542685
80Abdominal situs inversus (HP:0003363)1.88313697
81Abnormality of abdominal situs (HP:0011620)1.88313697
82Abnormal ventriculo-arterial connection (HP:0011563)1.87978193
83Transposition of the great arteries (HP:0001669)1.87978193
84Abnormal connection of the cardiac segments (HP:0011545)1.87978193
85Oral leukoplakia (HP:0002745)1.85718454
86Abnormality of the duodenum (HP:0002246)1.85517666
87Abnormality of methionine metabolism (HP:0010901)1.85271884
88Truncus arteriosus (HP:0001660)1.85106352
89Abnormal mitochondria in muscle tissue (HP:0008316)1.84679217
90Triphalangeal thumb (HP:0001199)1.83632335
91Sclerocornea (HP:0000647)1.83560151
92Bifid tongue (HP:0010297)1.82584610
93Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.82076395
94Abnormality of alanine metabolism (HP:0010916)1.82076395
95Hyperalaninemia (HP:0003348)1.82076395
96Gastrointestinal atresia (HP:0002589)1.82040558
97Anal stenosis (HP:0002025)1.80734985
98Stenosis of the external auditory canal (HP:0000402)1.79195448
99Premature ovarian failure (HP:0008209)1.78788758
100Aplasia/hypoplasia of the humerus (HP:0006507)1.78309146
101Hypoplastic pelvis (HP:0008839)1.78296797
102Renal Fanconi syndrome (HP:0001994)1.77627116
103Hepatocellular necrosis (HP:0001404)1.76925571
104Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.76087663
105Pancreatic fibrosis (HP:0100732)1.74510655
106Cerebral edema (HP:0002181)1.74217366
107Tongue fasciculations (HP:0001308)1.73759784
108Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.72754634
109Anophthalmia (HP:0000528)1.72743465
110Anencephaly (HP:0002323)1.72731733
111Rhabdomyosarcoma (HP:0002859)1.72711867
112Astrocytoma (HP:0009592)1.72670508
113Abnormality of the astrocytes (HP:0100707)1.72670508
114Secondary amenorrhea (HP:0000869)1.71589360
115Intestinal fistula (HP:0100819)1.71242048
116Ectopic kidney (HP:0000086)1.70773335
117Bile duct proliferation (HP:0001408)1.69338100
118Abnormal biliary tract physiology (HP:0012439)1.69338100
119Abnormality of chromosome stability (HP:0003220)1.69249950
120Rough bone trabeculation (HP:0100670)1.68969608
121Pancreatic cysts (HP:0001737)1.68396386
122Dandy-Walker malformation (HP:0001305)1.68014883
123Hepatic necrosis (HP:0002605)1.67836793
124Preaxial hand polydactyly (HP:0001177)1.67386746
125High anterior hairline (HP:0009890)1.67375928
126Breast aplasia (HP:0100783)1.67144091
127Neoplasm of the pancreas (HP:0002894)1.66955787
128Renal cortical cysts (HP:0000803)1.66642031
129Absent eyebrow (HP:0002223)1.66254670
130Poor coordination (HP:0002370)1.66195952
131Abnormality of the carotid arteries (HP:0005344)1.66083894
132Abnormality of the renal cortex (HP:0011035)1.64861361
133Increased serum lactate (HP:0002151)1.64514153
134Rimmed vacuoles (HP:0003805)1.63789361
135Esophageal atresia (HP:0002032)1.63339065
136Medial flaring of the eyebrow (HP:0010747)1.62617612
137Renal hypoplasia (HP:0000089)1.61914458
138Adrenal hypoplasia (HP:0000835)1.61841758
139Orthostatic hypotension (HP:0001278)1.61364827
140Abnormality of glycolysis (HP:0004366)1.61055032
141Increased serum pyruvate (HP:0003542)1.61055032
142Abnormality of aspartate family amino acid metabolism (HP:0010899)1.59984788
143Gait imbalance (HP:0002141)1.59952281
144Glioma (HP:0009733)1.59749086
145Sloping forehead (HP:0000340)1.59281518
146Decreased testicular size (HP:0008734)1.59214408
147Progressive macrocephaly (HP:0004481)1.58926111
148Micropenis (HP:0000054)1.58741400
149Vaginal fistula (HP:0004320)1.58225449
150Proximal placement of thumb (HP:0009623)1.58188294
151Aganglionic megacolon (HP:0002251)1.58059910
152Chronic hepatic failure (HP:0100626)1.57922053
153Atresia of the external auditory canal (HP:0000413)1.56443153
154Protruding tongue (HP:0010808)1.55408506
155Urethral obstruction (HP:0000796)1.55203288

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.13202927
2CDC73.14461311
3MKNK23.12296417
4TRIM283.02896249
5MKNK12.88817652
6WEE12.84868567
7TSSK62.79376980
8AKT32.69837624
9NUAK12.49328978
10SRPK12.48465951
11PLK32.27030286
12MST42.25692266
13TTK2.23399847
14PNCK2.20523299
15CASK2.16018249
16ACVR1B2.14993262
17NEK12.14582129
18WNK31.99748908
19EIF2AK31.97882610
20TNIK1.94924427
21STK38L1.90092516
22PLK11.87001076
23CDK121.86880147
24BRD41.86025088
25PLK41.81552322
26MAP4K21.76379595
27PLK21.67022751
28NEK21.58580809
29PDK21.52867173
30FRK1.48652381
31VRK21.39716556
32LATS11.39414801
33DYRK21.37495779
34CCNB11.34802387
35VRK11.33049300
36BRAF1.32009448
37AURKA1.31539305
38PINK11.30485628
39BMPR1B1.28547875
40MAPK131.27889686
41CDK191.27854586
42CHEK21.26746015
43CDK81.24911766
44MAP3K41.21400437
45STK161.21333387
46STK391.20955104
47CDK71.19907654
48LATS21.18684515
49MAP3K91.16596748
50PDK31.16060893
51PDK41.16060893
52NME11.15777922
53MARK11.13296580
54AURKB1.09538408
55CHEK11.06353967
56MAP2K71.06196365
57INSRR1.02490454
58DYRK31.01625983
59KSR10.98155315
60PASK0.96616297
61TAF10.93658986
62ATR0.91013473
63GRK70.90578821
64MAP3K60.90075618
65BMPR20.89305371
66EPHA40.87287420
67WNK40.87284336
68EIF2AK10.86944171
69OXSR10.84673717
70BCR0.82913633
71ATM0.82514340
72CSNK1G30.78285908
73CDK20.77522531
74DYRK1A0.75216412
75CSNK1E0.73267604
76ERBB30.72673015
77CDK10.71779176
78MELK0.69765038
79NEK60.67552998
80MAP3K120.67231838
81YES10.67141043
82FGFR20.65134725
83STK240.65093024
84TLK10.65039033
85EPHA30.64643677
86CDK30.63923883
87CSNK1A1L0.63697492
88BCKDK0.62176538
89RPS6KA40.61878891
90PAK30.61612776
91MOS0.59614388
92CSNK2A20.57558156
93NTRK30.56983537
94RPS6KB20.55933035
95OBSCN0.55657179
96CDK40.55492404
97PRKCI0.55247739
98CSNK2A10.55127257
99NEK90.54916889
100MET0.54237035
101GRK10.53942920
102CSNK1G10.53903335
103PRKCE0.52759875
104SIK30.52122828
105CSNK1G20.50759538
106RAF10.50695088
107BRSK20.49964922
108EPHB20.49956859
109FGFR10.49703676
110MAP2K40.47981849
111EPHA20.46967170
112ARAF0.45907137
113PBK0.45196113
114EIF2AK20.45034809
115MINK10.44218628
116UHMK10.42583034
117ZAK0.41430405
118ERBB40.39299321
119TGFBR10.38731138
120GSK3B0.38722178
121STK30.38514266
122ADRBK20.38172640
123AKT20.38126583
124BRSK10.37966031
125PRKCG0.37866827
126GRK50.35190172
127CDK90.35030960
128CAMK2B0.34887488
129TAOK20.34730153
130LIMK10.34654305
131ALK0.34478023
132MAPK140.32764728
133PRKDC0.32333371
134SGK20.32084506

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.05918391
2Mismatch repair_Homo sapiens_hsa034303.79598108
3RNA polymerase_Homo sapiens_hsa030203.76701750
4RNA transport_Homo sapiens_hsa030133.64496092
5Spliceosome_Homo sapiens_hsa030403.52504383
6DNA replication_Homo sapiens_hsa030303.38089243
7Proteasome_Homo sapiens_hsa030503.27374280
8Cell cycle_Homo sapiens_hsa041102.83940526
9Homologous recombination_Homo sapiens_hsa034402.70503404
10Nucleotide excision repair_Homo sapiens_hsa034202.62874627
11mRNA surveillance pathway_Homo sapiens_hsa030152.56300255
12Basal transcription factors_Homo sapiens_hsa030222.45515447
13Fanconi anemia pathway_Homo sapiens_hsa034602.41365047
14Base excision repair_Homo sapiens_hsa034102.33976820
15RNA degradation_Homo sapiens_hsa030182.16381496
16Pyrimidine metabolism_Homo sapiens_hsa002402.15268265
17One carbon pool by folate_Homo sapiens_hsa006702.03269679
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.98683280
19Propanoate metabolism_Homo sapiens_hsa006401.95894037
20Steroid biosynthesis_Homo sapiens_hsa001001.87982749
21Oocyte meiosis_Homo sapiens_hsa041141.85148448
22Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.74541263
23Vitamin B6 metabolism_Homo sapiens_hsa007501.67615929
24Huntingtons disease_Homo sapiens_hsa050161.57666414
25Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.49544513
26Purine metabolism_Homo sapiens_hsa002301.43654961
27Oxidative phosphorylation_Homo sapiens_hsa001901.35094423
28Ribosome_Homo sapiens_hsa030101.30475424
29Butanoate metabolism_Homo sapiens_hsa006501.28262287
30Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.27781579
31Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.27354377
32Parkinsons disease_Homo sapiens_hsa050121.27301766
33Non-homologous end-joining_Homo sapiens_hsa034501.23856860
34Nicotine addiction_Homo sapiens_hsa050331.19860197
35Hippo signaling pathway_Homo sapiens_hsa043901.09005843
36Epstein-Barr virus infection_Homo sapiens_hsa051691.03023386
37p53 signaling pathway_Homo sapiens_hsa041150.99834501
38Basal cell carcinoma_Homo sapiens_hsa052170.93522092
39Cysteine and methionine metabolism_Homo sapiens_hsa002700.92371824
40Fatty acid elongation_Homo sapiens_hsa000620.90556064
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.89793441
42Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.87940251
43Peroxisome_Homo sapiens_hsa041460.87554718
44Caffeine metabolism_Homo sapiens_hsa002320.87310926
45Wnt signaling pathway_Homo sapiens_hsa043100.82946412
46Hedgehog signaling pathway_Homo sapiens_hsa043400.81563501
47Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.78214268
48TGF-beta signaling pathway_Homo sapiens_hsa043500.78120020
49Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.73067441
50Biosynthesis of amino acids_Homo sapiens_hsa012300.72761736
51Phototransduction_Homo sapiens_hsa047440.71862976
52Alzheimers disease_Homo sapiens_hsa050100.71629867
532-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.70797395
54Tight junction_Homo sapiens_hsa045300.69431656
55Cardiac muscle contraction_Homo sapiens_hsa042600.69203586
56Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.67898590
57Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.67463904
58Amphetamine addiction_Homo sapiens_hsa050310.63909524
59Regulation of autophagy_Homo sapiens_hsa041400.62813633
60Protein export_Homo sapiens_hsa030600.62582352
61Circadian rhythm_Homo sapiens_hsa047100.61573352
62Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.60874077
63Sulfur metabolism_Homo sapiens_hsa009200.58346990
64Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.56907232
65Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.56878912
66Dopaminergic synapse_Homo sapiens_hsa047280.54909027
67Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.54525241
68Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54266021
69Drug metabolism - other enzymes_Homo sapiens_hsa009830.54114175
70Taste transduction_Homo sapiens_hsa047420.51421881
71Thyroid cancer_Homo sapiens_hsa052160.49241870
72Primary bile acid biosynthesis_Homo sapiens_hsa001200.46394257
73Arginine and proline metabolism_Homo sapiens_hsa003300.46190106
74Nitrogen metabolism_Homo sapiens_hsa009100.45508497
75Serotonergic synapse_Homo sapiens_hsa047260.44757883
76Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44039197
77Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.43089318
78Fatty acid metabolism_Homo sapiens_hsa012120.42730131
79Pentose and glucuronate interconversions_Homo sapiens_hsa000400.41480524
80Colorectal cancer_Homo sapiens_hsa052100.41390600
81Long-term potentiation_Homo sapiens_hsa047200.41366875
82Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.40735205
83Carbon metabolism_Homo sapiens_hsa012000.40441075
84N-Glycan biosynthesis_Homo sapiens_hsa005100.38883493
85Folate biosynthesis_Homo sapiens_hsa007900.38647239
86Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.36572484
87Adherens junction_Homo sapiens_hsa045200.36282989
88Axon guidance_Homo sapiens_hsa043600.34811668
89HTLV-I infection_Homo sapiens_hsa051660.34663366
90Lysine degradation_Homo sapiens_hsa003100.34544769
91Pyruvate metabolism_Homo sapiens_hsa006200.34175089
92Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.33693562
93Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.32879536
94MicroRNAs in cancer_Homo sapiens_hsa052060.32493384
95beta-Alanine metabolism_Homo sapiens_hsa004100.32050519
96Vibrio cholerae infection_Homo sapiens_hsa051100.31636696
97Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.31622941
98Metabolic pathways_Homo sapiens_hsa011000.31392295
99Notch signaling pathway_Homo sapiens_hsa043300.31203011
100Steroid hormone biosynthesis_Homo sapiens_hsa001400.30673942
101Long-term depression_Homo sapiens_hsa047300.28558705
102Maturity onset diabetes of the young_Homo sapiens_hsa049500.27929752
103Retinol metabolism_Homo sapiens_hsa008300.26995338
104Sulfur relay system_Homo sapiens_hsa041220.25271344
105Tryptophan metabolism_Homo sapiens_hsa003800.25044435
106Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.24475928
107Chemical carcinogenesis_Homo sapiens_hsa052040.23373476
108Collecting duct acid secretion_Homo sapiens_hsa049660.23228340
109Vitamin digestion and absorption_Homo sapiens_hsa049770.22404889
110Fatty acid degradation_Homo sapiens_hsa000710.21790421
111Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.21765500
112Melanogenesis_Homo sapiens_hsa049160.20675635
113Selenocompound metabolism_Homo sapiens_hsa004500.20501357
114FoxO signaling pathway_Homo sapiens_hsa040680.19601972
115Olfactory transduction_Homo sapiens_hsa047400.19559074
116Gap junction_Homo sapiens_hsa045400.18745030
117Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.18397349
118Synaptic vesicle cycle_Homo sapiens_hsa047210.18046971
119Linoleic acid metabolism_Homo sapiens_hsa005910.17978952
120Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.17200225
121Glucagon signaling pathway_Homo sapiens_hsa049220.16099104
122Glutamatergic synapse_Homo sapiens_hsa047240.14909976
123Alcoholism_Homo sapiens_hsa050340.14549325
124Viral carcinogenesis_Homo sapiens_hsa052030.14404202
125Ether lipid metabolism_Homo sapiens_hsa005650.14253875
126Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.14235909
127Glutathione metabolism_Homo sapiens_hsa004800.13996658
128Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.13050058
129Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.12163399
130Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.11848648
131Pathways in cancer_Homo sapiens_hsa052000.11767854

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