Rank | Gene Set | Z-score |
---|---|---|
1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 8.16874314 |
2 | ATP synthesis coupled proton transport (GO:0015986) | 7.79677123 |
3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 7.79677123 |
4 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 7.28484380 |
5 | chaperone-mediated protein transport (GO:0072321) | 6.60012749 |
6 | ribosomal small subunit biogenesis (GO:0042274) | 6.59033411 |
7 | respiratory electron transport chain (GO:0022904) | 6.51047450 |
8 | viral transcription (GO:0019083) | 6.48245386 |
9 | electron transport chain (GO:0022900) | 6.35324721 |
10 | translational termination (GO:0006415) | 6.24373852 |
11 | cotranslational protein targeting to membrane (GO:0006613) | 5.82981578 |
12 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.78650755 |
13 | protein targeting to ER (GO:0045047) | 5.74460781 |
14 | ribosomal small subunit assembly (GO:0000028) | 5.69282344 |
15 | protein localization to endoplasmic reticulum (GO:0070972) | 5.56189700 |
16 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.46528771 |
17 | maturation of 5.8S rRNA (GO:0000460) | 5.39497299 |
18 | proteasome assembly (GO:0043248) | 5.24773473 |
19 | translational elongation (GO:0006414) | 5.22810387 |
20 | protein neddylation (GO:0045116) | 5.22572004 |
21 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.04259889 |
22 | viral life cycle (GO:0019058) | 5.00280349 |
23 | cellular protein complex disassembly (GO:0043624) | 4.98350321 |
24 | protein complex biogenesis (GO:0070271) | 4.91749671 |
25 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.87743551 |
26 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.87743551 |
27 | NADH dehydrogenase complex assembly (GO:0010257) | 4.87743551 |
28 | DNA deamination (GO:0045006) | 4.75060992 |
29 | ribosomal large subunit biogenesis (GO:0042273) | 4.72813806 |
30 | maturation of SSU-rRNA (GO:0030490) | 4.71698503 |
31 | translational initiation (GO:0006413) | 4.51176417 |
32 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.48722777 |
33 | translation (GO:0006412) | 4.47767232 |
34 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.45242786 |
35 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.34540279 |
36 | termination of RNA polymerase III transcription (GO:0006386) | 4.34540279 |
37 | GTP biosynthetic process (GO:0006183) | 4.17720628 |
38 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.16238189 |
39 | protein targeting to mitochondrion (GO:0006626) | 4.15973846 |
40 | protein complex disassembly (GO:0043241) | 4.12055767 |
41 | establishment of protein localization to mitochondrion (GO:0072655) | 4.07341967 |
42 | hydrogen ion transmembrane transport (GO:1902600) | 4.01525849 |
43 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.99673525 |
44 | regulation of mitochondrial translation (GO:0070129) | 3.95729544 |
45 | ATP biosynthetic process (GO:0006754) | 3.94517210 |
46 | macromolecular complex disassembly (GO:0032984) | 3.93087877 |
47 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.92342768 |
48 | protein targeting to membrane (GO:0006612) | 3.90487341 |
49 | protein-cofactor linkage (GO:0018065) | 3.87125671 |
50 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.78688452 |
51 | platelet dense granule organization (GO:0060155) | 3.78410380 |
52 | inner mitochondrial membrane organization (GO:0007007) | 3.76807924 |
53 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.75964050 |
54 | protein localization to mitochondrion (GO:0070585) | 3.74734633 |
55 | nucleotide transmembrane transport (GO:1901679) | 3.69253852 |
56 | rRNA modification (GO:0000154) | 3.65486912 |
57 | oxidative phosphorylation (GO:0006119) | 3.65114518 |
58 | cellular component biogenesis (GO:0044085) | 3.63996475 |
59 | respiratory chain complex IV assembly (GO:0008535) | 3.59727458 |
60 | 7-methylguanosine mRNA capping (GO:0006370) | 3.59315093 |
61 | spliceosomal snRNP assembly (GO:0000387) | 3.56604485 |
62 | proton transport (GO:0015992) | 3.56497360 |
63 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.56143739 |
64 | negative regulation of ligase activity (GO:0051352) | 3.56143739 |
65 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.56093558 |
66 | UTP biosynthetic process (GO:0006228) | 3.56056860 |
67 | protein import into peroxisome matrix (GO:0016558) | 3.55955170 |
68 | 7-methylguanosine RNA capping (GO:0009452) | 3.55253508 |
69 | RNA capping (GO:0036260) | 3.55253508 |
70 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.55070872 |
71 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.50277040 |
72 | pseudouridine synthesis (GO:0001522) | 3.48147063 |
73 | establishment of integrated proviral latency (GO:0075713) | 3.48019978 |
74 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.47562457 |
75 | cullin deneddylation (GO:0010388) | 3.47373949 |
76 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.46956125 |
77 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.46956125 |
78 | hydrogen transport (GO:0006818) | 3.46928936 |
79 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.46892394 |
80 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.43967245 |
81 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.43352634 |
82 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.43352634 |
83 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.43352634 |
84 | deoxyribonucleotide catabolic process (GO:0009264) | 3.43160813 |
85 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.41196044 |
86 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.37603718 |
87 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.34511768 |
88 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.34431092 |
89 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.33112453 |
90 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.33112453 |
91 | intracellular protein transmembrane import (GO:0044743) | 3.32409678 |
92 | protein deneddylation (GO:0000338) | 3.30958742 |
93 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.27481283 |
94 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.24395575 |
95 | deoxyribose phosphate catabolic process (GO:0046386) | 3.24031776 |
96 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.23627880 |
97 | base-excision repair, AP site formation (GO:0006285) | 3.23463733 |
98 | establishment of viral latency (GO:0019043) | 3.20171873 |
99 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.20156723 |
100 | mitochondrial transport (GO:0006839) | 3.19444213 |
101 | cytochrome complex assembly (GO:0017004) | 3.19179340 |
102 | axon ensheathment in central nervous system (GO:0032291) | 3.19095829 |
103 | central nervous system myelination (GO:0022010) | 3.19095829 |
104 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.18410430 |
105 | peptidyl-histidine modification (GO:0018202) | 3.16629416 |
106 | metallo-sulfur cluster assembly (GO:0031163) | 3.16331189 |
107 | iron-sulfur cluster assembly (GO:0016226) | 3.16331189 |
108 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.14323354 |
109 | nucleoside triphosphate biosynthetic process (GO:0009142) | 3.14227078 |
110 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.13865076 |
111 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.13865076 |
112 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.11104612 |
113 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.08223966 |
114 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.08050569 |
115 | intracellular protein transmembrane transport (GO:0065002) | 3.07530613 |
116 | nucleoside diphosphate phosphorylation (GO:0006165) | 3.05566477 |
117 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 3.05037666 |
118 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.04600762 |
119 | CTP biosynthetic process (GO:0006241) | 3.04082598 |
120 | CTP metabolic process (GO:0046036) | 3.04082598 |
121 | positive regulation of prostaglandin secretion (GO:0032308) | 3.03850558 |
122 | rRNA processing (GO:0006364) | 3.02504875 |
123 | negative regulation of B cell apoptotic process (GO:0002903) | 3.00946020 |
124 | purine nucleoside monophosphate biosynthetic process (GO:0009127) | 3.00914425 |
125 | purine ribonucleoside monophosphate biosynthetic process (GO:0009168) | 3.00914425 |
126 | rRNA metabolic process (GO:0016072) | 3.00351741 |
127 | UTP metabolic process (GO:0046051) | 2.99946460 |
128 | protein targeting (GO:0006605) | 2.99910413 |
129 | lipopolysaccharide biosynthetic process (GO:0009103) | 2.97097923 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 5.90198804 |
2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.89192516 |
3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.79644770 |
4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.45283005 |
5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.17634829 |
6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.12432931 |
7 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.80803257 |
8 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.79200208 |
9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.58662409 |
10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.49668806 |
11 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.46328859 |
12 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.38253501 |
13 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 3.32618712 |
14 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.29604571 |
15 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.01127702 |
16 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.83920223 |
17 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.67829065 |
18 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.56822871 |
19 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.49412205 |
20 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.41783764 |
21 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.38421838 |
22 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.30889130 |
23 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.28365647 |
24 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 2.20488803 |
25 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.20380549 |
26 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.19564923 |
27 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.17208741 |
28 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.14708247 |
29 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.09266793 |
30 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.95533115 |
31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.92311082 |
32 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.91688511 |
33 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.77221412 |
34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.72193112 |
35 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.69128485 |
36 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.63264045 |
37 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.53741069 |
38 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.52892599 |
39 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.51815893 |
40 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.49968409 |
41 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.49339547 |
42 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.36851343 |
43 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.36651169 |
44 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.31742173 |
45 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.31080306 |
46 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.30654116 |
47 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.29887324 |
48 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.29134897 |
49 | VDR_22108803_ChIP-Seq_LS180_Human | 1.26845234 |
50 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.26363209 |
51 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.26329219 |
52 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.26035975 |
53 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.24967705 |
54 | * TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.24618156 |
55 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.20662838 |
56 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.18777479 |
57 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.18647910 |
58 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.18148721 |
59 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.16776082 |
60 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.15972464 |
61 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.15437872 |
62 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.15076023 |
63 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.14379309 |
64 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.12687791 |
65 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.10667923 |
66 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.09422307 |
67 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.08621944 |
68 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.06980841 |
69 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.06969527 |
70 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.06365582 |
71 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.05973060 |
72 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.05015754 |
73 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.04717869 |
74 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.02820048 |
75 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.00877173 |
76 | P68_20966046_ChIP-Seq_HELA_Human | 0.99723744 |
77 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.98444803 |
78 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.97549506 |
79 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.95473035 |
80 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.94971285 |
81 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.94599011 |
82 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.94173279 |
83 | ERA_21632823_ChIP-Seq_H3396_Human | 0.94130586 |
84 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.93633529 |
85 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.92596586 |
86 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.90676474 |
87 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.89902625 |
88 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.89034592 |
89 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.88937835 |
90 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.88540753 |
91 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.88374987 |
92 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.87616107 |
93 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.87473236 |
94 | P300_27268052_Chip-Seq_Bcells_Human | 0.87236120 |
95 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.86703792 |
96 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.86389636 |
97 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.84908001 |
98 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.84849604 |
99 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.84523272 |
100 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.84290577 |
101 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.84076945 |
102 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.83467032 |
103 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.82342231 |
104 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.82114274 |
105 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.80421747 |
106 | SA1_27219007_Chip-Seq_Bcells_Human | 0.79872563 |
107 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.78674344 |
108 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.77416763 |
109 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.77285909 |
110 | FUS_26573619_Chip-Seq_HEK293_Human | 0.76157378 |
111 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.73596262 |
112 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.71890504 |
113 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.71491512 |
114 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.71476537 |
115 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.71232044 |
116 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.70409805 |
117 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.68558200 |
118 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.67241273 |
119 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.65912958 |
120 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.62706151 |
121 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.62527310 |
122 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.62464629 |
123 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.60546781 |
124 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.60303899 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0009379_abnormal_foot_pigmentation | 5.18784892 |
2 | MP0001529_abnormal_vocalization | 3.94522532 |
3 | MP0001905_abnormal_dopamine_level | 3.27417477 |
4 | MP0003136_yellow_coat_color | 3.25723162 |
5 | MP0003880_abnormal_central_pattern | 2.89872648 |
6 | MP0001986_abnormal_taste_sensitivity | 2.74623408 |
7 | MP0002254_reproductive_system_inflammat | 2.73882245 |
8 | MP0003693_abnormal_embryo_hatching | 2.33737657 |
9 | MP0005409_darkened_coat_color | 2.31964712 |
10 | MP0006036_abnormal_mitochondrial_physio | 2.28351568 |
11 | MP0000372_irregular_coat_pigmentation | 2.27644308 |
12 | MP0003186_abnormal_redox_activity | 2.25270555 |
13 | MP0003806_abnormal_nucleotide_metabolis | 2.20111047 |
14 | MP0004142_abnormal_muscle_tone | 2.18813548 |
15 | MP0004381_abnormal_hair_follicle | 2.11236780 |
16 | MP0005646_abnormal_pituitary_gland | 2.01788498 |
17 | MP0002736_abnormal_nociception_after | 1.96943215 |
18 | MP0006276_abnormal_autonomic_nervous | 1.89235962 |
19 | MP0005410_abnormal_fertilization | 1.88268710 |
20 | MP0006035_abnormal_mitochondrial_morpho | 1.83095885 |
21 | MP0002163_abnormal_gland_morphology | 1.71987828 |
22 | MP0004147_increased_porphyrin_level | 1.71229958 |
23 | MP0001188_hyperpigmentation | 1.69845466 |
24 | MP0008932_abnormal_embryonic_tissue | 1.69180117 |
25 | MP0003718_maternal_effect | 1.68524460 |
26 | MP0000920_abnormal_myelination | 1.66886448 |
27 | MP0004957_abnormal_blastocyst_morpholog | 1.65440453 |
28 | MP0008875_abnormal_xenobiotic_pharmacok | 1.63708029 |
29 | MP0001346_abnormal_lacrimal_gland | 1.61546526 |
30 | MP0005408_hypopigmentation | 1.61236526 |
31 | MP0002653_abnormal_ependyma_morphology | 1.61144898 |
32 | MP0001873_stomach_inflammation | 1.57926832 |
33 | MP0005075_abnormal_melanosome_morpholog | 1.54661038 |
34 | MP0002160_abnormal_reproductive_system | 1.54291803 |
35 | MP0003011_delayed_dark_adaptation | 1.52816168 |
36 | MP0002272_abnormal_nervous_system | 1.52001794 |
37 | MP0001727_abnormal_embryo_implantation | 1.51517190 |
38 | MP0001968_abnormal_touch/_nociception | 1.50417008 |
39 | MP0002938_white_spotting | 1.46103709 |
40 | MP0002638_abnormal_pupillary_reflex | 1.44108015 |
41 | MP0005389_reproductive_system_phenotype | 1.43533629 |
42 | MP0005451_abnormal_body_composition | 1.42997794 |
43 | MP0005171_absent_coat_pigmentation | 1.41175418 |
44 | MP0002837_dystrophic_cardiac_calcinosis | 1.39435822 |
45 | MP0005379_endocrine/exocrine_gland_phen | 1.38898298 |
46 | MP0005645_abnormal_hypothalamus_physiol | 1.38787061 |
47 | MP0002735_abnormal_chemical_nociception | 1.35521524 |
48 | MP0006292_abnormal_olfactory_placode | 1.32222902 |
49 | MP0003786_premature_aging | 1.24590092 |
50 | MP0002132_abnormal_respiratory_system | 1.24551574 |
51 | MP0008057_abnormal_DNA_replication | 1.24072383 |
52 | MP0001919_abnormal_reproductive_system | 1.23242746 |
53 | MP0001970_abnormal_pain_threshold | 1.16500151 |
54 | MP0008995_early_reproductive_senescence | 1.16362857 |
55 | MP0008058_abnormal_DNA_repair | 1.15906626 |
56 | MP0000631_abnormal_neuroendocrine_gland | 1.14178384 |
57 | MP0002148_abnormal_hypersensitivity_rea | 1.12848887 |
58 | MP0003315_abnormal_perineum_morphology | 1.11156342 |
59 | MP0003950_abnormal_plasma_membrane | 1.10648658 |
60 | MP0001485_abnormal_pinna_reflex | 1.10508933 |
61 | MP0002822_catalepsy | 1.10242912 |
62 | MP0008789_abnormal_olfactory_epithelium | 1.09273767 |
63 | MP0002234_abnormal_pharynx_morphology | 1.05316061 |
64 | MP0002876_abnormal_thyroid_physiology | 1.05214720 |
65 | MP0003283_abnormal_digestive_organ | 1.01537120 |
66 | MP0008872_abnormal_physiological_respon | 1.00611796 |
67 | MP0001984_abnormal_olfaction | 1.00262757 |
68 | MP0002734_abnormal_mechanical_nocicepti | 0.99568443 |
69 | MP0003646_muscle_fatigue | 0.99536590 |
70 | MP0009046_muscle_twitch | 0.99196972 |
71 | MP0004133_heterotaxia | 0.98859800 |
72 | MP0003195_calcinosis | 0.98313979 |
73 | MP0005253_abnormal_eye_physiology | 0.98025678 |
74 | MP0005332_abnormal_amino_acid | 0.97393758 |
75 | MP0001542_abnormal_bone_strength | 0.97158741 |
76 | MP0005423_abnormal_somatic_nervous | 0.96065929 |
77 | MP0002064_seizures | 0.94589345 |
78 | MP0006072_abnormal_retinal_apoptosis | 0.94391884 |
79 | MP0004145_abnormal_muscle_electrophysio | 0.91939965 |
80 | MP0001440_abnormal_grooming_behavior | 0.91036119 |
81 | MP0005636_abnormal_mineral_homeostasis | 0.90464132 |
82 | MP0005084_abnormal_gallbladder_morpholo | 0.89400248 |
83 | MP0001853_heart_inflammation | 0.89201486 |
84 | MP0002909_abnormal_adrenal_gland | 0.89110071 |
85 | MP0002733_abnormal_thermal_nociception | 0.88657850 |
86 | MP0000049_abnormal_middle_ear | 0.88629385 |
87 | MP0000749_muscle_degeneration | 0.88549572 |
88 | MP0000015_abnormal_ear_pigmentation | 0.86797149 |
89 | MP0000639_abnormal_adrenal_gland | 0.86754291 |
90 | MP0001756_abnormal_urination | 0.86566401 |
91 | MP0003698_abnormal_male_reproductive | 0.86315739 |
92 | MP0004742_abnormal_vestibular_system | 0.85363126 |
93 | MP0002751_abnormal_autonomic_nervous | 0.85158908 |
94 | MP0001764_abnormal_homeostasis | 0.84914365 |
95 | MP0003787_abnormal_imprinting | 0.84575770 |
96 | MP0010386_abnormal_urinary_bladder | 0.83945534 |
97 | MP0003724_increased_susceptibility_to | 0.82868182 |
98 | MP0002210_abnormal_sex_determination | 0.82273341 |
99 | MP0005551_abnormal_eye_electrophysiolog | 0.81591911 |
100 | MP0002693_abnormal_pancreas_physiology | 0.81490497 |
101 | MP0009697_abnormal_copulation | 0.81270707 |
102 | MP0005670_abnormal_white_adipose | 0.80948242 |
103 | MP0001929_abnormal_gametogenesis | 0.80614657 |
104 | MP0002277_abnormal_respiratory_mucosa | 0.80314311 |
105 | MP0008877_abnormal_DNA_methylation | 0.79013480 |
106 | MP0005386_behavior/neurological_phenoty | 0.78974978 |
107 | MP0004924_abnormal_behavior | 0.78974978 |
108 | MP0005671_abnormal_response_to | 0.78244348 |
109 | MP0002229_neurodegeneration | 0.77843601 |
110 | MP0008873_increased_physiological_sensi | 0.77518468 |
111 | MP0002102_abnormal_ear_morphology | 0.75748048 |
112 | MP0000653_abnormal_sex_gland | 0.75732247 |
113 | MP0002752_abnormal_somatic_nervous | 0.75521750 |
114 | MP0005174_abnormal_tail_pigmentation | 0.74341672 |
115 | MP0009745_abnormal_behavioral_response | 0.73913995 |
116 | MP0010094_abnormal_chromosome_stability | 0.73657952 |
117 | MP0000230_abnormal_systemic_arterial | 0.72771061 |
118 | MP0003077_abnormal_cell_cycle | 0.72740473 |
119 | MP0002557_abnormal_social/conspecific_i | 0.72530846 |
120 | MP0002095_abnormal_skin_pigmentation | 0.72427624 |
121 | MP0009333_abnormal_splenocyte_physiolog | 0.72381488 |
122 | MP0009785_altered_susceptibility_to | 0.72033842 |
123 | MP0003938_abnormal_ear_development | 0.71881181 |
124 | MP0001963_abnormal_hearing_physiology | 0.71586921 |
125 | MP0003879_abnormal_hair_cell | 0.71309654 |
126 | MP0005083_abnormal_biliary_tract | 0.70355806 |
127 | MP0005266_abnormal_metabolism | 0.69763799 |
128 | MP0002067_abnormal_sensory_capabilities | 0.69527187 |
129 | MP0008004_abnormal_stomach_pH | 0.69521990 |
130 | MP0001663_abnormal_digestive_system | 0.69323605 |
131 | MP0000026_abnormal_inner_ear | 0.68878144 |
132 | MP0006082_CNS_inflammation | 0.68516844 |
133 | MP0000358_abnormal_cell_content/ | 0.68425336 |
134 | MP0001145_abnormal_male_reproductive | 0.67895019 |
135 | MP0002572_abnormal_emotion/affect_behav | 0.66834091 |
136 | MP0004270_analgesia | 0.66808044 |
137 | MP0003656_abnormal_erythrocyte_physiolo | 0.66587908 |
138 | MP0003121_genomic_imprinting | 0.66395519 |
139 | MP0005647_abnormal_sex_gland | 0.66080378 |
140 | MP0005195_abnormal_posterior_eye | 0.65623136 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 7.02498642 |
2 | Mitochondrial inheritance (HP:0001427) | 6.26745589 |
3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 6.24178642 |
4 | Progressive macrocephaly (HP:0004481) | 5.73458582 |
5 | Acute encephalopathy (HP:0006846) | 5.64148782 |
6 | Hepatocellular necrosis (HP:0001404) | 5.35277978 |
7 | Increased hepatocellular lipid droplets (HP:0006565) | 5.31178229 |
8 | Increased CSF lactate (HP:0002490) | 5.26307350 |
9 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.22640643 |
10 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 4.73255785 |
11 | Lipid accumulation in hepatocytes (HP:0006561) | 4.70995977 |
12 | Renal Fanconi syndrome (HP:0001994) | 4.67919462 |
13 | Abnormal number of erythroid precursors (HP:0012131) | 4.65796962 |
14 | Hepatic necrosis (HP:0002605) | 4.64041694 |
15 | 3-Methylglutaconic aciduria (HP:0003535) | 4.43801626 |
16 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 4.42881927 |
17 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 4.35151160 |
18 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 4.35151160 |
19 | Increased intramyocellular lipid droplets (HP:0012240) | 4.13756270 |
20 | Cerebral edema (HP:0002181) | 3.88006747 |
21 | Exertional dyspnea (HP:0002875) | 3.87987402 |
22 | Respiratory failure (HP:0002878) | 3.76137977 |
23 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.75196020 |
24 | Exercise intolerance (HP:0003546) | 3.73797830 |
25 | Optic disc pallor (HP:0000543) | 3.68043962 |
26 | Leukodystrophy (HP:0002415) | 3.66785664 |
27 | Lactic acidosis (HP:0003128) | 3.53175220 |
28 | Increased serum lactate (HP:0002151) | 3.48465908 |
29 | Macrocytic anemia (HP:0001972) | 3.46736704 |
30 | Reticulocytopenia (HP:0001896) | 3.46300760 |
31 | Increased muscle lipid content (HP:0009058) | 3.44553393 |
32 | Parakeratosis (HP:0001036) | 3.31921731 |
33 | Abnormality of glycolysis (HP:0004366) | 3.17326309 |
34 | Increased serum pyruvate (HP:0003542) | 3.17326309 |
35 | Respiratory difficulties (HP:0002880) | 3.03555991 |
36 | Abnormality of renal resorption (HP:0011038) | 3.00131476 |
37 | Pallor (HP:0000980) | 2.89648521 |
38 | Brushfield spots (HP:0001088) | 2.74934901 |
39 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.72842164 |
40 | Cerebral hypomyelination (HP:0006808) | 2.64297721 |
41 | Type I transferrin isoform profile (HP:0003642) | 2.48972956 |
42 | Testicular atrophy (HP:0000029) | 2.47482596 |
43 | Sensory axonal neuropathy (HP:0003390) | 2.44746341 |
44 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.39137561 |
45 | Generalized aminoaciduria (HP:0002909) | 2.34605645 |
46 | CNS demyelination (HP:0007305) | 2.29983779 |
47 | Hyperphosphaturia (HP:0003109) | 2.28174745 |
48 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.27860721 |
49 | Dicarboxylic aciduria (HP:0003215) | 2.27860721 |
50 | Molar tooth sign on MRI (HP:0002419) | 2.25103220 |
51 | Abnormality of midbrain morphology (HP:0002418) | 2.25103220 |
52 | X-linked dominant inheritance (HP:0001423) | 2.23647516 |
53 | Glycosuria (HP:0003076) | 2.23025448 |
54 | Abnormality of urine glucose concentration (HP:0011016) | 2.23025448 |
55 | Emotional lability (HP:0000712) | 2.19681849 |
56 | Pancreatic fibrosis (HP:0100732) | 2.14715262 |
57 | Pancreatic cysts (HP:0001737) | 2.13444236 |
58 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.12904378 |
59 | Oral leukoplakia (HP:0002745) | 2.10461077 |
60 | Microvesicular hepatic steatosis (HP:0001414) | 2.07467524 |
61 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.03616854 |
62 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.03616854 |
63 | Abnormality of the axillary hair (HP:0100134) | 1.99334804 |
64 | Abnormality of secondary sexual hair (HP:0009888) | 1.99334804 |
65 | Retinal dysplasia (HP:0007973) | 1.96441454 |
66 | Hypothermia (HP:0002045) | 1.96260245 |
67 | Lethargy (HP:0001254) | 1.95393250 |
68 | Abnormality of placental membranes (HP:0011409) | 1.95346979 |
69 | Amniotic constriction ring (HP:0009775) | 1.95346979 |
70 | True hermaphroditism (HP:0010459) | 1.93863840 |
71 | Asplenia (HP:0001746) | 1.92484647 |
72 | Stenosis of the external auditory canal (HP:0000402) | 1.92326510 |
73 | Progressive microcephaly (HP:0000253) | 1.90879619 |
74 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.90879558 |
75 | Medial flaring of the eyebrow (HP:0010747) | 1.89702270 |
76 | Congenital stationary night blindness (HP:0007642) | 1.88980437 |
77 | Microretrognathia (HP:0000308) | 1.86489985 |
78 | Congenital, generalized hypertrichosis (HP:0004540) | 1.86116558 |
79 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.85887949 |
80 | Sclerocornea (HP:0000647) | 1.83763951 |
81 | Abnormal ciliary motility (HP:0012262) | 1.83517466 |
82 | Opisthotonus (HP:0002179) | 1.81783959 |
83 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.81238475 |
84 | Epiphyseal stippling (HP:0010655) | 1.80803475 |
85 | Abnormal urine phosphate concentration (HP:0012599) | 1.80784590 |
86 | Hyperglycinemia (HP:0002154) | 1.80643466 |
87 | Abnormality of magnesium homeostasis (HP:0004921) | 1.79371852 |
88 | CNS hypomyelination (HP:0003429) | 1.77998839 |
89 | Delusions (HP:0000746) | 1.77884185 |
90 | Blindness (HP:0000618) | 1.77099098 |
91 | Abnormal pupillary function (HP:0007686) | 1.75994538 |
92 | Absent/shortened dynein arms (HP:0200106) | 1.75518044 |
93 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.75518044 |
94 | Aplastic anemia (HP:0001915) | 1.75239177 |
95 | Attenuation of retinal blood vessels (HP:0007843) | 1.75201336 |
96 | Polydipsia (HP:0001959) | 1.74745677 |
97 | Abnormal drinking behavior (HP:0030082) | 1.74745677 |
98 | Renal tubular dysfunction (HP:0000124) | 1.74292915 |
99 | Methylmalonic aciduria (HP:0012120) | 1.73055612 |
100 | Absent thumb (HP:0009777) | 1.73009994 |
101 | Myokymia (HP:0002411) | 1.72795813 |
102 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.69223106 |
103 | Methylmalonic acidemia (HP:0002912) | 1.68357227 |
104 | Patchy hypopigmentation of hair (HP:0011365) | 1.67627786 |
105 | Abnormal hemoglobin (HP:0011902) | 1.66531974 |
106 | Abnormal protein glycosylation (HP:0012346) | 1.66488072 |
107 | Abnormal glycosylation (HP:0012345) | 1.66488072 |
108 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.66488072 |
109 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.66488072 |
110 | Female pseudohermaphroditism (HP:0010458) | 1.66470486 |
111 | Progressive external ophthalmoplegia (HP:0000590) | 1.65873620 |
112 | Neuroendocrine neoplasm (HP:0100634) | 1.65139425 |
113 | Hyperthyroidism (HP:0000836) | 1.64900505 |
114 | Type II lissencephaly (HP:0007260) | 1.64180246 |
115 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.63361412 |
116 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.62008912 |
117 | Vomiting (HP:0002013) | 1.61578451 |
118 | Neutropenia (HP:0001875) | 1.60226910 |
119 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.59817536 |
120 | Polyuria (HP:0000103) | 1.57315303 |
121 | Pendular nystagmus (HP:0012043) | 1.56586768 |
122 | Sparse eyelashes (HP:0000653) | 1.55461041 |
123 | Concave nail (HP:0001598) | 1.54396778 |
124 | Congenital primary aphakia (HP:0007707) | 1.53535539 |
125 | Type 2 muscle fiber atrophy (HP:0003554) | 1.52374137 |
126 | Secondary amenorrhea (HP:0000869) | 1.50407281 |
127 | Poor head control (HP:0002421) | 1.49467909 |
128 | Rough bone trabeculation (HP:0100670) | 1.48577608 |
129 | Hypoplasia of the uterus (HP:0000013) | 1.48111550 |
130 | Muscle fiber atrophy (HP:0100295) | 1.47634004 |
131 | Pancytopenia (HP:0001876) | 1.46499661 |
132 | Gait imbalance (HP:0002141) | 1.45920489 |
133 | Poor suck (HP:0002033) | 1.45188504 |
134 | Nephrogenic diabetes insipidus (HP:0009806) | 1.42873695 |
135 | Pheochromocytoma (HP:0002666) | 1.41623731 |
136 | Breast hypoplasia (HP:0003187) | 1.40519743 |
Rank | Gene Set | Z-score |
---|---|---|
1 | VRK2 | 5.53801112 |
2 | NME2 | 4.14045918 |
3 | STK16 | 3.88814429 |
4 | PBK | 2.96436040 |
5 | BUB1 | 2.89478252 |
6 | NME1 | 2.75323279 |
7 | ARAF | 2.71837486 |
8 | STK39 | 2.63065287 |
9 | VRK1 | 2.47821116 |
10 | EIF2AK1 | 2.44285851 |
11 | PASK | 2.40457943 |
12 | PIM2 | 2.25151073 |
13 | EIF2AK3 | 2.17414158 |
14 | MST4 | 2.12278293 |
15 | MUSK | 2.12092450 |
16 | MAP3K12 | 2.10178370 |
17 | NUAK1 | 2.09011310 |
18 | WEE1 | 2.05653232 |
19 | MAPKAPK5 | 2.01412082 |
20 | TLK1 | 1.97094817 |
21 | GRK5 | 1.81901643 |
22 | BMPR1B | 1.80980502 |
23 | MAP4K2 | 1.65111730 |
24 | CASK | 1.64855777 |
25 | OXSR1 | 1.63425899 |
26 | LIMK1 | 1.61797218 |
27 | CDK19 | 1.56863824 |
28 | MYLK | 1.50092175 |
29 | BCR | 1.47448339 |
30 | BRAF | 1.29412712 |
31 | SRPK1 | 1.29388141 |
32 | PNCK | 1.25611137 |
33 | MAP3K11 | 1.23558106 |
34 | TNIK | 1.22765716 |
35 | GRK7 | 1.22405208 |
36 | WNK4 | 1.22336711 |
37 | CDC7 | 1.22045661 |
38 | PLK4 | 1.16145994 |
39 | TESK2 | 1.11840689 |
40 | BMPR2 | 1.09691290 |
41 | ADRBK2 | 1.08323044 |
42 | TAF1 | 1.08000846 |
43 | ABL2 | 1.06368664 |
44 | KDR | 1.01846726 |
45 | TESK1 | 1.00303229 |
46 | CSNK1G2 | 0.99065440 |
47 | NEK1 | 0.98656396 |
48 | RPS6KA5 | 0.93743989 |
49 | INSRR | 0.89703315 |
50 | TAOK3 | 0.88210643 |
51 | AURKA | 0.88095619 |
52 | PDK2 | 0.86243253 |
53 | WNK3 | 0.85151424 |
54 | LRRK2 | 0.82841652 |
55 | CAMK2B | 0.82673595 |
56 | CSNK1A1L | 0.82366414 |
57 | IRAK4 | 0.82124489 |
58 | CSNK1G3 | 0.81637105 |
59 | DYRK2 | 0.81548630 |
60 | FRK | 0.81134737 |
61 | DAPK1 | 0.81053464 |
62 | KIT | 0.80623503 |
63 | ITK | 0.80261318 |
64 | PHKG2 | 0.79453021 |
65 | PHKG1 | 0.79453021 |
66 | ILK | 0.78488426 |
67 | IRAK3 | 0.75763826 |
68 | BCKDK | 0.73910698 |
69 | CHEK2 | 0.72966260 |
70 | TSSK6 | 0.72307121 |
71 | CAMK2D | 0.69790833 |
72 | MKNK1 | 0.68628304 |
73 | IRAK2 | 0.64670472 |
74 | CSNK2A1 | 0.64461004 |
75 | TEC | 0.64077753 |
76 | FGR | 0.63553583 |
77 | CAMK2G | 0.63177885 |
78 | CSNK2A2 | 0.61274689 |
79 | CDK8 | 0.58396952 |
80 | ADRBK1 | 0.58046534 |
81 | PAK1 | 0.57691973 |
82 | UHMK1 | 0.57410059 |
83 | ZAK | 0.56752709 |
84 | PRKCI | 0.56043105 |
85 | CAMKK1 | 0.55846949 |
86 | CLK1 | 0.55229963 |
87 | OBSCN | 0.53565335 |
88 | GRK1 | 0.53138535 |
89 | MAPK15 | 0.52871326 |
90 | IRAK1 | 0.52562503 |
91 | MAP3K13 | 0.52051602 |
92 | RIPK4 | 0.51899524 |
93 | DAPK3 | 0.51707064 |
94 | EIF2AK2 | 0.51260900 |
95 | ROCK2 | 0.50619601 |
96 | CAMK2A | 0.50370843 |
97 | ATR | 0.49231256 |
98 | MAP2K7 | 0.49100257 |
99 | TXK | 0.48806537 |
100 | DYRK3 | 0.48697985 |
101 | PRKCG | 0.47042866 |
102 | MAPK13 | 0.47019056 |
103 | MAP2K6 | 0.46085511 |
104 | PLK1 | 0.46031404 |
105 | CDK14 | 0.43623101 |
106 | CCNB1 | 0.42206463 |
107 | PLK2 | 0.41745416 |
108 | PKN1 | 0.41380421 |
109 | CSNK1A1 | 0.40849188 |
110 | IKBKB | 0.40502753 |
111 | STK4 | 0.39838163 |
112 | CDK11A | 0.39617958 |
113 | STK24 | 0.39344414 |
114 | CSNK1G1 | 0.39202114 |
115 | YES1 | 0.38883116 |
116 | RPS6KB2 | 0.38798271 |
117 | TIE1 | 0.37881045 |
118 | TNK2 | 0.37630355 |
119 | GRK6 | 0.36949596 |
120 | PRKACA | 0.36910251 |
121 | PRKCE | 0.36866668 |
122 | ACVR1B | 0.36539937 |
123 | NEK6 | 0.36218422 |
124 | LYN | 0.36079349 |
125 | PLK3 | 0.35680150 |
126 | AURKB | 0.35537120 |
127 | MAP2K2 | 0.35504136 |
128 | CDK18 | 0.34771974 |
129 | MOS | 0.34755876 |
130 | PINK1 | 0.34257843 |
131 | TBK1 | 0.32555562 |
132 | PRKCQ | 0.31926494 |
133 | EPHB2 | 0.31541494 |
134 | PRKCA | 0.31438272 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 5.68158788 |
2 | Ribosome_Homo sapiens_hsa03010 | 5.48907568 |
3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.89006600 |
4 | Proteasome_Homo sapiens_hsa03050 | 4.10627543 |
5 | Alzheimers disease_Homo sapiens_hsa05010 | 3.61296729 |
6 | Huntingtons disease_Homo sapiens_hsa05016 | 3.56751777 |
7 | RNA polymerase_Homo sapiens_hsa03020 | 3.42775625 |
8 | Protein export_Homo sapiens_hsa03060 | 3.21217923 |
9 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 3.04335229 |
10 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.11505871 |
11 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.00243644 |
12 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.81785567 |
13 | DNA replication_Homo sapiens_hsa03030 | 1.71825940 |
14 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.69216273 |
15 | Spliceosome_Homo sapiens_hsa03040 | 1.63187052 |
16 | Homologous recombination_Homo sapiens_hsa03440 | 1.50157528 |
17 | Mismatch repair_Homo sapiens_hsa03430 | 1.47403194 |
18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.47064552 |
19 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.46050250 |
20 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.44481971 |
21 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.40115477 |
22 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.39413208 |
23 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.37250135 |
24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.33107283 |
25 | Purine metabolism_Homo sapiens_hsa00230 | 1.18004826 |
26 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.13101745 |
27 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.06267007 |
28 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.05480412 |
29 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.04848519 |
30 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.03669610 |
31 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.03583191 |
32 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.01591751 |
33 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.97354380 |
34 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.95179242 |
35 | Base excision repair_Homo sapiens_hsa03410 | 0.90676445 |
36 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.88633632 |
37 | Metabolic pathways_Homo sapiens_hsa01100 | 0.88422777 |
38 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.88103542 |
39 | Phototransduction_Homo sapiens_hsa04744 | 0.87050395 |
40 | RNA degradation_Homo sapiens_hsa03018 | 0.84033329 |
41 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.83316895 |
42 | RNA transport_Homo sapiens_hsa03013 | 0.82831845 |
43 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.80489330 |
44 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.78025526 |
45 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.77213196 |
46 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.75807785 |
47 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.74623478 |
48 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.71919848 |
49 | Sulfur relay system_Homo sapiens_hsa04122 | 0.63509577 |
50 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.63264912 |
51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.60440572 |
52 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.60278646 |
53 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.59278584 |
54 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.56946353 |
55 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.53307770 |
56 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.52152498 |
57 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.49639173 |
58 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.49494119 |
59 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.49303317 |
60 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.48379453 |
61 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.47320766 |
62 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.47241894 |
63 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.46673854 |
64 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.45211415 |
65 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.44496075 |
66 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.43306668 |
67 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.42618961 |
68 | Asthma_Homo sapiens_hsa05310 | 0.41519882 |
69 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.40639028 |
70 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.39620986 |
71 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.39443999 |
72 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.39333206 |
73 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.39279602 |
74 | Histidine metabolism_Homo sapiens_hsa00340 | 0.38998767 |
75 | Phagosome_Homo sapiens_hsa04145 | 0.38330273 |
76 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.38120730 |
77 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.36905486 |
78 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.36881587 |
79 | Retinol metabolism_Homo sapiens_hsa00830 | 0.35583035 |
80 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.34284454 |
81 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.32910767 |
82 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.32906848 |
83 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.32792141 |
84 | Alcoholism_Homo sapiens_hsa05034 | 0.32600942 |
85 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.31895693 |
86 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.30159332 |
87 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.29347052 |
88 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.28814527 |
89 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.28795371 |
90 | Allograft rejection_Homo sapiens_hsa05330 | 0.28263595 |
91 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.27848757 |
92 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.27443302 |
93 | Olfactory transduction_Homo sapiens_hsa04740 | 0.26731272 |
94 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.25826915 |
95 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.25647512 |
96 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.25536857 |
97 | Peroxisome_Homo sapiens_hsa04146 | 0.24618167 |
98 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.24480753 |
99 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.24086159 |
100 | Mineral absorption_Homo sapiens_hsa04978 | 0.23563021 |
101 | Cell cycle_Homo sapiens_hsa04110 | 0.22052275 |
102 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.21610219 |
103 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.20656436 |
104 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.20545638 |
105 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.20222550 |
106 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.18754219 |
107 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.17674923 |
108 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.17335549 |
109 | Carbon metabolism_Homo sapiens_hsa01200 | 0.14459935 |
110 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.13717782 |
111 | Taste transduction_Homo sapiens_hsa04742 | 0.12226114 |
112 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.11452411 |
113 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.10865568 |
114 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.09673406 |
115 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.08980983 |
116 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.08890431 |
117 | Other glycan degradation_Homo sapiens_hsa00511 | 0.08850088 |
118 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.08402780 |
119 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.08172828 |
120 | Nicotine addiction_Homo sapiens_hsa05033 | 0.07614721 |
121 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.05998580 |
122 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.05708449 |
123 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.03235407 |
124 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.02642959 |