

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | interferon-gamma production (GO:0032609) | 9.33805900 |
| 2 | negative regulation of T cell mediated immunity (GO:0002710) | 7.67456566 |
| 3 | positive regulation of T cell chemotaxis (GO:0010820) | 7.34571396 |
| 4 | regulation of T cell chemotaxis (GO:0010819) | 7.34571396 |
| 5 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 7.31185673 |
| 6 | positive regulation of T cell cytokine production (GO:0002726) | 7.30724057 |
| 7 | positive regulation of T-helper 1 type immune response (GO:0002827) | 6.28606030 |
| 8 | negative regulation of interleukin-2 production (GO:0032703) | 5.83235608 |
| 9 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 5.77511752 |
| 10 | regulation of T cell mediated cytotoxicity (GO:0001914) | 5.71282122 |
| 11 | lymphocyte chemotaxis (GO:0048247) | 5.22981416 |
| 12 | positive regulation of type 2 immune response (GO:0002830) | 5.02202106 |
| 13 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.92183561 |
| 14 | positive regulation of transforming growth factor beta production (GO:0071636) | 4.71598026 |
| 15 | regulation of T-helper 1 type immune response (GO:0002825) | 4.68596117 |
| 16 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 4.52308213 |
| 17 | positive regulation of neutrophil chemotaxis (GO:0090023) | 4.45040572 |
| 18 | positive regulation of neutrophil migration (GO:1902624) | 4.45040572 |
| 19 | regulation of T cell cytokine production (GO:0002724) | 4.42168082 |
| 20 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 4.42072724 |
| 21 | regulation of lymphocyte chemotaxis (GO:1901623) | 4.33320634 |
| 22 | negative regulation of cytokine production involved in immune response (GO:0002719) | 4.14839096 |
| 23 | negative regulation of adaptive immune response (GO:0002820) | 4.10916804 |
| 24 | protein K6-linked ubiquitination (GO:0085020) | 4.04975071 |
| 25 | receptor guanylyl cyclase signaling pathway (GO:0007168) | 4.03064702 |
| 26 | positive regulation of granulocyte chemotaxis (GO:0071624) | 3.90498201 |
| 27 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.90459296 |
| 28 | sleep (GO:0030431) | 3.87221582 |
| 29 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.82766930 |
| 30 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.78992016 |
| 31 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.72100499 |
| 32 | phosphorelay signal transduction system (GO:0000160) | 3.71271658 |
| 33 | male meiosis (GO:0007140) | 3.70970914 |
| 34 | histone H3-K4 trimethylation (GO:0080182) | 3.66880724 |
| 35 | negative regulation of alpha-beta T cell activation (GO:0046636) | 3.66306811 |
| 36 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 3.65890269 |
| 37 | cellular response to interleukin-4 (GO:0071353) | 3.63967929 |
| 38 | positive regulation of immunoglobulin production (GO:0002639) | 3.62729603 |
| 39 | positive regulation of T cell migration (GO:2000406) | 3.61437747 |
| 40 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.61102443 |
| 41 | proline transport (GO:0015824) | 3.57098319 |
| 42 | lymphocyte migration (GO:0072676) | 3.55898063 |
| 43 | regulation of T cell migration (GO:2000404) | 3.52782792 |
| 44 | negative regulation of production of molecular mediator of immune response (GO:0002701) | 3.51209353 |
| 45 | methionine biosynthetic process (GO:0009086) | 3.50975830 |
| 46 | positive regulation of T cell mediated immunity (GO:0002711) | 3.46618280 |
| 47 | negative regulation of viral transcription (GO:0032897) | 3.45891565 |
| 48 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.45516166 |
| 49 | interleukin-6-mediated signaling pathway (GO:0070102) | 3.38964815 |
| 50 | positive regulation of release of sequestered calcium ion into cytosol (GO:0051281) | 3.37749132 |
| 51 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 3.35500647 |
| 52 | regulation of neutrophil migration (GO:1902622) | 3.34518872 |
| 53 | regulation of neutrophil chemotaxis (GO:0090022) | 3.34518872 |
| 54 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.32255275 |
| 55 | cellular response to ethanol (GO:0071361) | 3.32007793 |
| 56 | positive regulation of defense response to virus by host (GO:0002230) | 3.31695899 |
| 57 | leukotriene biosynthetic process (GO:0019370) | 3.31498367 |
| 58 | aspartate family amino acid biosynthetic process (GO:0009067) | 3.25536876 |
| 59 | negative regulation of execution phase of apoptosis (GO:1900118) | 3.24193152 |
| 60 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.23058497 |
| 61 | interferon-gamma secretion (GO:0072643) | 3.22032644 |
| 62 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 3.21689214 |
| 63 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.19784047 |
| 64 | lipopolysaccharide biosynthetic process (GO:0009103) | 3.19513526 |
| 65 | positive regulation of cell killing (GO:0031343) | 3.17672111 |
| 66 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.14819443 |
| 67 | autophagic vacuole fusion (GO:0000046) | 3.14251113 |
| 68 | hepatocyte apoptotic process (GO:0097284) | 3.11465175 |
| 69 | regulation of cell killing (GO:0031341) | 3.09505493 |
| 70 | mannosylation (GO:0097502) | 3.09314511 |
| 71 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 3.08312168 |
| 72 | glucosamine-containing compound catabolic process (GO:1901072) | 3.08073522 |
| 73 | lipopolysaccharide metabolic process (GO:0008653) | 3.04954357 |
| 74 | coenzyme A metabolic process (GO:0015936) | 3.04557798 |
| 75 | negative regulation of glucose transport (GO:0010829) | 3.02169646 |
| 76 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.01999803 |
| 77 | regulation of T cell mediated immunity (GO:0002709) | 3.00669649 |
| 78 | ribonucleoprotein complex disassembly (GO:0032988) | 3.00352899 |
| 79 | metallo-sulfur cluster assembly (GO:0031163) | 2.93068621 |
| 80 | iron-sulfur cluster assembly (GO:0016226) | 2.93068621 |
| 81 | response to interleukin-4 (GO:0070670) | 2.92902538 |
| 82 | positive regulation of lymphocyte migration (GO:2000403) | 2.92703379 |
| 83 | cGMP metabolic process (GO:0046068) | 2.92596188 |
| 84 | methionine metabolic process (GO:0006555) | 2.89608804 |
| 85 | rhodopsin mediated signaling pathway (GO:0016056) | 2.87825957 |
| 86 | piRNA metabolic process (GO:0034587) | 2.86637902 |
| 87 | positive regulation of granulocyte differentiation (GO:0030854) | 2.86160691 |
| 88 | mitochondrial genome maintenance (GO:0000002) | 2.85488704 |
| 89 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.82778020 |
| 90 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.80302090 |
| 91 | positive regulation of B cell mediated immunity (GO:0002714) | 2.79540841 |
| 92 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.79540841 |
| 93 | negative regulation of glucose import (GO:0046325) | 2.78893342 |
| 94 | natural killer cell differentiation (GO:0001779) | 2.78433551 |
| 95 | glomerular basement membrane development (GO:0032836) | 2.74070067 |
| 96 | DNA deamination (GO:0045006) | 2.73815878 |
| 97 | positive thymic T cell selection (GO:0045059) | 2.73746738 |
| 98 | regulation of gamma-delta T cell activation (GO:0046643) | 2.72094587 |
| 99 | regulation of glucokinase activity (GO:0033131) | 2.71021576 |
| 100 | regulation of hexokinase activity (GO:1903299) | 2.71021576 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.55443613 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.29870918 |
| 3 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 3.90817349 |
| 4 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.90083704 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.33855239 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.28234817 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 3.02125642 |
| 8 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.97352252 |
| 9 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.60230673 |
| 10 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.54109919 |
| 11 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.53959429 |
| 12 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.51334754 |
| 13 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.39397340 |
| 14 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.31932309 |
| 15 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.14638816 |
| 16 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.97686251 |
| 17 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.84131177 |
| 18 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.83858429 |
| 19 | MYB_26560356_Chip-Seq_TH2_Human | 1.81265230 |
| 20 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.80275338 |
| 21 | GATA1_22025678_ChIP-Seq_K562_Human | 1.79009997 |
| 22 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.78457057 |
| 23 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.78055441 |
| 24 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.68304619 |
| 25 | GATA3_26560356_Chip-Seq_TH2_Human | 1.66304200 |
| 26 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.57268816 |
| 27 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.53105259 |
| 28 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.52523351 |
| 29 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.49276163 |
| 30 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.48532573 |
| 31 | FUS_26573619_Chip-Seq_HEK293_Human | 1.40051544 |
| 32 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.39457743 |
| 33 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.38316060 |
| 34 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.37097889 |
| 35 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.36624781 |
| 36 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.36458443 |
| 37 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.34757451 |
| 38 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.30706524 |
| 39 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.30581715 |
| 40 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.30580739 |
| 41 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.30414217 |
| 42 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.27115435 |
| 43 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.26693852 |
| 44 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.26406351 |
| 45 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.26333307 |
| 46 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.26248961 |
| 47 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.19527645 |
| 48 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.19527645 |
| 49 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.19219964 |
| 50 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.18847357 |
| 51 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.17067268 |
| 52 | EWS_26573619_Chip-Seq_HEK293_Human | 1.15560911 |
| 53 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15279216 |
| 54 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.14509711 |
| 55 | GATA3_26560356_Chip-Seq_TH1_Human | 1.14171526 |
| 56 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.13092244 |
| 57 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.12799121 |
| 58 | STAT3_23295773_ChIP-Seq_U87_Human | 1.12226975 |
| 59 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.11561492 |
| 60 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.11561492 |
| 61 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.10596384 |
| 62 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.10432638 |
| 63 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 1.09881275 |
| 64 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.08898418 |
| 65 | TCF4_23295773_ChIP-Seq_U87_Human | 1.06863551 |
| 66 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.05688667 |
| 67 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.05478360 |
| 68 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.04406408 |
| 69 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.04029322 |
| 70 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.02609181 |
| 71 | NCOR_22424771_ChIP-Seq_293T_Human | 1.02501118 |
| 72 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.01935887 |
| 73 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.01046706 |
| 74 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.00897351 |
| 75 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.00873557 |
| 76 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.00099151 |
| 77 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.99372938 |
| 78 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.99370386 |
| 79 | AR_20517297_ChIP-Seq_VCAP_Human | 0.99112984 |
| 80 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.98455671 |
| 81 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.97143062 |
| 82 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.96671399 |
| 83 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.96562211 |
| 84 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.96175840 |
| 85 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.94924003 |
| 86 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.94663236 |
| 87 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.93972801 |
| 88 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.92703562 |
| 89 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.92577354 |
| 90 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.92374397 |
| 91 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.92372289 |
| 92 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.92212394 |
| 93 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.91322113 |
| 94 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.90519929 |
| 95 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.90168539 |
| 96 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.89224578 |
| 97 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.88426947 |
| 98 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.87852139 |
| 99 | MYB_26560356_Chip-Seq_TH1_Human | 0.87816734 |
| 100 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.87750725 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005310_abnormal_salivary_gland | 4.35055212 |
| 2 | MP0008877_abnormal_DNA_methylation | 4.24342560 |
| 3 | MP0000569_abnormal_digit_pigmentation | 3.70768729 |
| 4 | MP0003195_calcinosis | 3.41426282 |
| 5 | MP0002876_abnormal_thyroid_physiology | 3.28601128 |
| 6 | MP0003646_muscle_fatigue | 3.19563806 |
| 7 | MP0002006_tumorigenesis | 2.77360836 |
| 8 | MP0005671_abnormal_response_to | 2.66702236 |
| 9 | MP0002653_abnormal_ependyma_morphology | 2.48965217 |
| 10 | MP0000015_abnormal_ear_pigmentation | 2.31605950 |
| 11 | MP0009840_abnormal_foam_cell | 2.30819059 |
| 12 | MP0003656_abnormal_erythrocyte_physiolo | 2.24119746 |
| 13 | MP0003011_delayed_dark_adaptation | 2.18557210 |
| 14 | MP0000613_abnormal_salivary_gland | 2.02928442 |
| 15 | MP0002102_abnormal_ear_morphology | 1.95201793 |
| 16 | MP0005551_abnormal_eye_electrophysiolog | 1.90087042 |
| 17 | MP0003191_abnormal_cellular_cholesterol | 1.89812686 |
| 18 | MP0003763_abnormal_thymus_physiology | 1.87606877 |
| 19 | MP0005075_abnormal_melanosome_morpholog | 1.86192301 |
| 20 | MP0003045_fibrosis | 1.75518817 |
| 21 | MP0002396_abnormal_hematopoietic_system | 1.68944927 |
| 22 | MP0003786_premature_aging | 1.67390235 |
| 23 | MP0009333_abnormal_splenocyte_physiolog | 1.65516484 |
| 24 | MP0001800_abnormal_humoral_immune | 1.64594581 |
| 25 | MP0005000_abnormal_immune_tolerance | 1.64442071 |
| 26 | MP0004808_abnormal_hematopoietic_stem | 1.58177922 |
| 27 | MP0002723_abnormal_immune_serum | 1.52362585 |
| 28 | MP0004130_abnormal_muscle_cell | 1.49833359 |
| 29 | MP0005174_abnormal_tail_pigmentation | 1.47128305 |
| 30 | MP0001501_abnormal_sleep_pattern | 1.45621265 |
| 31 | MP0000013_abnormal_adipose_tissue | 1.43429537 |
| 32 | MP0003303_peritoneal_inflammation | 1.41650005 |
| 33 | MP0010386_abnormal_urinary_bladder | 1.37086449 |
| 34 | MP0002254_reproductive_system_inflammat | 1.36281159 |
| 35 | MP0003329_amyloid_beta_deposits | 1.33457920 |
| 36 | MP0002452_abnormal_antigen_presenting | 1.32061114 |
| 37 | MP0009046_muscle_twitch | 1.31485272 |
| 38 | MP0001270_distended_abdomen | 1.28879259 |
| 39 | MP0001819_abnormal_immune_cell | 1.28772532 |
| 40 | MP0002420_abnormal_adaptive_immunity | 1.27098419 |
| 41 | MP0004145_abnormal_muscle_electrophysio | 1.25353897 |
| 42 | MP0010368_abnormal_lymphatic_system | 1.24402677 |
| 43 | MP0002398_abnormal_bone_marrow | 1.24059008 |
| 44 | MP0002148_abnormal_hypersensitivity_rea | 1.23554725 |
| 45 | MP0002168_other_aberrant_phenotype | 1.20077892 |
| 46 | MP0002722_abnormal_immune_system | 1.15151047 |
| 47 | MP0005253_abnormal_eye_physiology | 1.14596180 |
| 48 | MP0005647_abnormal_sex_gland | 1.12949472 |
| 49 | MP0004036_abnormal_muscle_relaxation | 1.08734457 |
| 50 | MP0000689_abnormal_spleen_morphology | 1.08382991 |
| 51 | MP0000604_amyloidosis | 1.06070162 |
| 52 | MP0005025_abnormal_response_to | 1.04207630 |
| 53 | MP0004084_abnormal_cardiac_muscle | 1.02849752 |
| 54 | MP0004134_abnormal_chest_morphology | 1.02441382 |
| 55 | MP0008872_abnormal_physiological_respon | 1.01820634 |
| 56 | MP0004142_abnormal_muscle_tone | 1.00622858 |
| 57 | MP0000716_abnormal_immune_system | 0.99774943 |
| 58 | MP0001661_extended_life_span | 0.97724539 |
| 59 | MP0005360_urolithiasis | 0.97551669 |
| 60 | MP0003172_abnormal_lysosome_physiology | 0.97078803 |
| 61 | MP0002419_abnormal_innate_immunity | 0.96623424 |
| 62 | MP0003724_increased_susceptibility_to | 0.96608347 |
| 63 | MP0005395_other_phenotype | 0.95344212 |
| 64 | MP0004233_abnormal_muscle_weight | 0.93688550 |
| 65 | MP0006035_abnormal_mitochondrial_morpho | 0.93222795 |
| 66 | MP0003718_maternal_effect | 0.92675236 |
| 67 | MP0003950_abnormal_plasma_membrane | 0.91652850 |
| 68 | MP0010329_abnormal_lipoprotein_level | 0.90983633 |
| 69 | MP0000427_abnormal_hair_cycle | 0.90919220 |
| 70 | MP0002229_neurodegeneration | 0.90735752 |
| 71 | MP0003866_abnormal_defecation | 0.90330593 |
| 72 | MP0009785_altered_susceptibility_to | 0.89852707 |
| 73 | MP0010094_abnormal_chromosome_stability | 0.89837566 |
| 74 | MP0004043_abnormal_pH_regulation | 0.87361866 |
| 75 | MP0001845_abnormal_inflammatory_respons | 0.86927447 |
| 76 | MP0000703_abnormal_thymus_morphology | 0.84940346 |
| 77 | MP0001529_abnormal_vocalization | 0.83935155 |
| 78 | MP0002136_abnormal_kidney_physiology | 0.82133809 |
| 79 | MP0002429_abnormal_blood_cell | 0.81508152 |
| 80 | MP0004185_abnormal_adipocyte_glucose | 0.73232483 |
| 81 | MP0003943_abnormal_hepatobiliary_system | 0.72128019 |
| 82 | MP0005167_abnormal_blood-brain_barrier | 0.71553599 |
| 83 | MP0008995_early_reproductive_senescence | 0.69503435 |
| 84 | MP0003959_abnormal_lean_body | 0.69492335 |
| 85 | MP0008775_abnormal_heart_ventricle | 0.69423401 |
| 86 | MP0004924_abnormal_behavior | 0.68759524 |
| 87 | MP0005386_behavior/neurological_phenoty | 0.68759524 |
| 88 | MP0005332_abnormal_amino_acid | 0.66495809 |
| 89 | MP0001764_abnormal_homeostasis | 0.65339879 |
| 90 | MP0004484_altered_response_of | 0.64998579 |
| 91 | MP0003448_altered_tumor_morphology | 0.63812558 |
| 92 | MP0002019_abnormal_tumor_incidence | 0.63780235 |
| 93 | MP0001545_abnormal_hematopoietic_system | 0.62538071 |
| 94 | MP0005397_hematopoietic_system_phenotyp | 0.62538071 |
| 95 | MP0009745_abnormal_behavioral_response | 0.62129745 |
| 96 | MP0005058_abnormal_lysosome_morphology | 0.62020992 |
| 97 | MP0001664_abnormal_digestion | 0.62005958 |
| 98 | MP0009703_decreased_birth_body | 0.61415040 |
| 99 | MP0009643_abnormal_urine_homeostasis | 0.59723515 |
| 100 | MP0008469_abnormal_protein_level | 0.59364347 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Retrobulbar optic neuritis (HP:0100654) | 7.55073218 |
| 2 | Optic neuritis (HP:0100653) | 7.55073218 |
| 3 | Orchitis (HP:0100796) | 6.74948222 |
| 4 | Myositis (HP:0100614) | 5.64803679 |
| 5 | Decreased central vision (HP:0007663) | 5.27885618 |
| 6 | Keratoconjunctivitis (HP:0001096) | 5.12104954 |
| 7 | Keratoconjunctivitis sicca (HP:0001097) | 5.05643627 |
| 8 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 4.84906113 |
| 9 | Increased corneal curvature (HP:0100692) | 4.35606094 |
| 10 | Keratoconus (HP:0000563) | 4.35606094 |
| 11 | Arterial thrombosis (HP:0004420) | 4.14768081 |
| 12 | Nonimmune hydrops fetalis (HP:0001790) | 3.89900662 |
| 13 | Beaking of vertebral bodies (HP:0004568) | 3.80401616 |
| 14 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.73315850 |
| 15 | Pulmonary infiltrates (HP:0002113) | 3.52619215 |
| 16 | Keratitis (HP:0000491) | 3.48168927 |
| 17 | Type I transferrin isoform profile (HP:0003642) | 3.47669009 |
| 18 | Microvesicular hepatic steatosis (HP:0001414) | 3.30723481 |
| 19 | Abnormality of the pericardium (HP:0001697) | 3.27540307 |
| 20 | Visual hallucinations (HP:0002367) | 3.21396532 |
| 21 | Abnormality of the labia minora (HP:0012880) | 3.09739552 |
| 22 | Hypoplastic ischia (HP:0003175) | 3.07697643 |
| 23 | Hemoptysis (HP:0002105) | 3.06525376 |
| 24 | Attenuation of retinal blood vessels (HP:0007843) | 3.05397799 |
| 25 | Focal motor seizures (HP:0011153) | 3.01206062 |
| 26 | J-shaped sella turcica (HP:0002680) | 2.99889069 |
| 27 | Abnormality of lateral ventricle (HP:0030047) | 2.87442887 |
| 28 | Gangrene (HP:0100758) | 2.82664799 |
| 29 | Hypoplasia of the pons (HP:0012110) | 2.82579888 |
| 30 | Anorexia (HP:0002039) | 2.82528394 |
| 31 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.81248586 |
| 32 | Encephalitis (HP:0002383) | 2.71356859 |
| 33 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.70048604 |
| 34 | Polyneuropathy (HP:0001271) | 2.69689555 |
| 35 | Supranuclear gaze palsy (HP:0000605) | 2.69415594 |
| 36 | Congenital stationary night blindness (HP:0007642) | 2.68167488 |
| 37 | Abnormality of homocysteine metabolism (HP:0010919) | 2.65616149 |
| 38 | Homocystinuria (HP:0002156) | 2.65616149 |
| 39 | Abnormality of the pons (HP:0007361) | 2.65338933 |
| 40 | Abnormality of the ischium (HP:0003174) | 2.64034861 |
| 41 | Cone-rod dystrophy (HP:0000548) | 2.62677732 |
| 42 | Agammaglobulinemia (HP:0004432) | 2.60088442 |
| 43 | Abnormality of the pleura (HP:0002103) | 2.59800361 |
| 44 | Abnormal protein glycosylation (HP:0012346) | 2.58245979 |
| 45 | Abnormal glycosylation (HP:0012345) | 2.58245979 |
| 46 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.58245979 |
| 47 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.58245979 |
| 48 | Abnormality of macular pigmentation (HP:0008002) | 2.57646908 |
| 49 | Type II lissencephaly (HP:0007260) | 2.54398521 |
| 50 | Acne (HP:0001061) | 2.51209026 |
| 51 | Abnormality of glycolipid metabolism (HP:0010969) | 2.49996414 |
| 52 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.49996414 |
| 53 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.49996414 |
| 54 | Menstrual irregularities (HP:0000858) | 2.46510517 |
| 55 | Horizontal nystagmus (HP:0000666) | 2.45180209 |
| 56 | Cerebellar dysplasia (HP:0007033) | 2.44338397 |
| 57 | Slow saccadic eye movements (HP:0000514) | 2.41838210 |
| 58 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.39131277 |
| 59 | Lipid accumulation in hepatocytes (HP:0006561) | 2.37408291 |
| 60 | Pulmonary embolism (HP:0002204) | 2.34092887 |
| 61 | Gastrointestinal infarctions (HP:0005244) | 2.30009648 |
| 62 | Abnormality of the aortic arch (HP:0012303) | 2.28379458 |
| 63 | Abnormal auditory evoked potentials (HP:0006958) | 2.25040219 |
| 64 | Mitral stenosis (HP:0001718) | 2.19410943 |
| 65 | IgG deficiency (HP:0004315) | 2.16832799 |
| 66 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.13424909 |
| 67 | Recurrent cutaneous fungal infections (HP:0011370) | 2.13424909 |
| 68 | Recurrent corneal erosions (HP:0000495) | 2.10716879 |
| 69 | Cutaneous melanoma (HP:0012056) | 2.09555051 |
| 70 | Thrombophlebitis (HP:0004418) | 2.06264657 |
| 71 | Glomerulopathy (HP:0100820) | 2.01531635 |
| 72 | Abnormality of the pubic bones (HP:0003172) | 2.01474824 |
| 73 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.99906869 |
| 74 | Follicular hyperkeratosis (HP:0007502) | 1.99232225 |
| 75 | Vasculitis (HP:0002633) | 1.95489348 |
| 76 | Hyperglycinuria (HP:0003108) | 1.94819408 |
| 77 | Prominent nose (HP:0000448) | 1.92929244 |
| 78 | Agitation (HP:0000713) | 1.91170474 |
| 79 | Prostate neoplasm (HP:0100787) | 1.89659940 |
| 80 | Pancreatic fibrosis (HP:0100732) | 1.89252676 |
| 81 | Abnormality of the endocardium (HP:0004306) | 1.87103995 |
| 82 | Vertigo (HP:0002321) | 1.86310954 |
| 83 | Megaloblastic anemia (HP:0001889) | 1.84856824 |
| 84 | Neoplasm of the heart (HP:0100544) | 1.84372149 |
| 85 | Chest pain (HP:0100749) | 1.84188287 |
| 86 | Abnormality of the epiphyses of the phalanges of the hand (HP:0005920) | 1.83637036 |
| 87 | Meningitis (HP:0001287) | 1.82734649 |
| 88 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.82274951 |
| 89 | Abnormality of the prostate (HP:0008775) | 1.80626244 |
| 90 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.79401380 |
| 91 | Abnormality of serum amino acid levels (HP:0003112) | 1.76621132 |
| 92 | Fair hair (HP:0002286) | 1.74780941 |
| 93 | Cerebral hypomyelination (HP:0006808) | 1.71070856 |
| 94 | Metaphyseal dysplasia (HP:0100255) | 1.65817145 |
| 95 | Abnormality of the epiphyses of the hand (HP:0005924) | 1.63743524 |
| 96 | Pendular nystagmus (HP:0012043) | 1.63287387 |
| 97 | Abnormality of the lumbar spine (HP:0100712) | 1.62889246 |
| 98 | Central scotoma (HP:0000603) | 1.62812165 |
| 99 | Striae distensae (HP:0001065) | 1.61066238 |
| 100 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.60742628 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NEK9 | 4.39739717 |
| 2 | TAOK3 | 4.32196614 |
| 3 | IRAK4 | 4.31886539 |
| 4 | CAMKK2 | 4.11118885 |
| 5 | BRSK2 | 3.73443631 |
| 6 | PKN2 | 3.63543750 |
| 7 | FES | 3.18509573 |
| 8 | FLT3 | 3.13997059 |
| 9 | TXK | 3.02567486 |
| 10 | TLK1 | 2.64412821 |
| 11 | MAP3K4 | 2.53868694 |
| 12 | PIK3CG | 2.40506178 |
| 13 | EPHA3 | 2.15059764 |
| 14 | ZAK | 2.06832028 |
| 15 | JAK3 | 1.91012045 |
| 16 | PINK1 | 1.76107290 |
| 17 | IRAK1 | 1.71581284 |
| 18 | CAMKK1 | 1.68820372 |
| 19 | MAP3K14 | 1.58904531 |
| 20 | WNK4 | 1.48420210 |
| 21 | ADRBK2 | 1.44693095 |
| 22 | ERN1 | 1.34757864 |
| 23 | TEC | 1.22845932 |
| 24 | AKT3 | 1.16254133 |
| 25 | DYRK1B | 1.13532064 |
| 26 | MET | 1.13284847 |
| 27 | WNK3 | 1.13122503 |
| 28 | TSSK6 | 1.08253127 |
| 29 | TRPM7 | 1.07893993 |
| 30 | FRK | 1.07339940 |
| 31 | BTK | 1.04992497 |
| 32 | BRSK1 | 1.02019377 |
| 33 | PAK2 | 1.00974856 |
| 34 | MATK | 1.00446193 |
| 35 | OXSR1 | 0.98839876 |
| 36 | MAPK11 | 0.98805716 |
| 37 | HCK | 0.98598629 |
| 38 | IKBKB | 0.97213724 |
| 39 | BCKDK | 0.97070827 |
| 40 | MAP3K13 | 0.89901764 |
| 41 | IKBKE | 0.87623890 |
| 42 | SYK | 0.84710987 |
| 43 | PRKCQ | 0.84610482 |
| 44 | TYK2 | 0.80800778 |
| 45 | PRKAA2 | 0.74837919 |
| 46 | MELK | 0.68229150 |
| 47 | NTRK3 | 0.67678875 |
| 48 | STK38L | 0.67496201 |
| 49 | ABL1 | 0.66591763 |
| 50 | MAP2K6 | 0.63922911 |
| 51 | ITK | 0.63076212 |
| 52 | IRAK2 | 0.62303303 |
| 53 | GRK1 | 0.62117948 |
| 54 | STK39 | 0.60661563 |
| 55 | MAPKAPK5 | 0.59964972 |
| 56 | CSK | 0.59446170 |
| 57 | SRPK1 | 0.57129859 |
| 58 | IGF1R | 0.54581137 |
| 59 | ATR | 0.53627832 |
| 60 | LCK | 0.53313829 |
| 61 | ACVR1B | 0.51498078 |
| 62 | EIF2AK2 | 0.51089047 |
| 63 | FER | 0.48339535 |
| 64 | MAPK7 | 0.47362673 |
| 65 | ADRBK1 | 0.47188169 |
| 66 | TBK1 | 0.46684886 |
| 67 | PHKG1 | 0.46275593 |
| 68 | PHKG2 | 0.46275593 |
| 69 | MINK1 | 0.45427503 |
| 70 | MAP2K3 | 0.45289093 |
| 71 | DAPK1 | 0.45050112 |
| 72 | KIT | 0.43012462 |
| 73 | LYN | 0.42939317 |
| 74 | PBK | 0.42358512 |
| 75 | OBSCN | 0.42342510 |
| 76 | MAPK3 | 0.40277660 |
| 77 | JAK2 | 0.38634674 |
| 78 | RPS6KB2 | 0.38569219 |
| 79 | MAP2K2 | 0.36435983 |
| 80 | MAPKAPK3 | 0.35235518 |
| 81 | EPHB1 | 0.33402313 |
| 82 | DYRK1A | 0.31036785 |
| 83 | WNK1 | 0.30446158 |
| 84 | MAP3K7 | 0.29644573 |
| 85 | CHEK1 | 0.29221902 |
| 86 | BMPR1B | 0.25841093 |
| 87 | STK11 | 0.25567191 |
| 88 | PRKAA1 | 0.24751353 |
| 89 | CHUK | 0.24413626 |
| 90 | MAPK1 | 0.23557348 |
| 91 | TAF1 | 0.22313255 |
| 92 | ERBB3 | 0.21951963 |
| 93 | NUAK1 | 0.21798337 |
| 94 | CDK4 | 0.19260438 |
| 95 | PIM2 | 0.18832208 |
| 96 | MAPK13 | 0.17612663 |
| 97 | MAPK8 | 0.17542006 |
| 98 | JAK1 | 0.17479432 |
| 99 | NME1 | 0.16454742 |
| 100 | EIF2AK3 | 0.16408741 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | One carbon pool by folate_Homo sapiens_hsa00670 | 3.98086948 |
| 2 | Phototransduction_Homo sapiens_hsa04744 | 3.79757301 |
| 3 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.41638494 |
| 4 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 2.90815012 |
| 5 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.36374940 |
| 6 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.23622186 |
| 7 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 2.22656952 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.17309209 |
| 9 | Olfactory transduction_Homo sapiens_hsa04740 | 2.10219298 |
| 10 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.02210577 |
| 11 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.94446086 |
| 12 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.89951609 |
| 13 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.86116875 |
| 14 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.82760397 |
| 15 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.79398693 |
| 16 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.76176486 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 1.75430483 |
| 18 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.69505787 |
| 19 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.68230122 |
| 20 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.68032792 |
| 21 | Protein export_Homo sapiens_hsa03060 | 1.67954970 |
| 22 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.67260066 |
| 23 | Malaria_Homo sapiens_hsa05144 | 1.66807233 |
| 24 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.47643549 |
| 25 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.33312112 |
| 26 | Circadian rhythm_Homo sapiens_hsa04710 | 1.32419818 |
| 27 | Purine metabolism_Homo sapiens_hsa00230 | 1.27938622 |
| 28 | Other glycan degradation_Homo sapiens_hsa00511 | 1.24436413 |
| 29 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.22243740 |
| 30 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.20300507 |
| 31 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.18119942 |
| 32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.18083915 |
| 33 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.16291167 |
| 34 | Lysosome_Homo sapiens_hsa04142 | 1.14854328 |
| 35 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.13740288 |
| 36 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.13678219 |
| 37 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.11871424 |
| 38 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.11513508 |
| 39 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.06876310 |
| 40 | Basal transcription factors_Homo sapiens_hsa03022 | 1.05658629 |
| 41 | ABC transporters_Homo sapiens_hsa02010 | 1.05572921 |
| 42 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.04589019 |
| 43 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.99576285 |
| 44 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.94417968 |
| 45 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.92461288 |
| 46 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.92216749 |
| 47 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.89081459 |
| 48 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.88526189 |
| 49 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.88432603 |
| 50 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.87604120 |
| 51 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.84390522 |
| 52 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.76290174 |
| 53 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.74626653 |
| 54 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.74018565 |
| 55 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.73862497 |
| 56 | Measles_Homo sapiens_hsa05162 | 0.72595173 |
| 57 | Asthma_Homo sapiens_hsa05310 | 0.72430930 |
| 58 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.72354659 |
| 59 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.70675679 |
| 60 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.69366922 |
| 61 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.68861617 |
| 62 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.67460751 |
| 63 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.66185405 |
| 64 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.64202302 |
| 65 | Allograft rejection_Homo sapiens_hsa05330 | 0.63799077 |
| 66 | Morphine addiction_Homo sapiens_hsa05032 | 0.62571159 |
| 67 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.62327052 |
| 68 | Leishmaniasis_Homo sapiens_hsa05140 | 0.61787306 |
| 69 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.60003805 |
| 70 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.56646963 |
| 71 | RNA degradation_Homo sapiens_hsa03018 | 0.56538362 |
| 72 | Insulin resistance_Homo sapiens_hsa04931 | 0.55278541 |
| 73 | Legionellosis_Homo sapiens_hsa05134 | 0.51987262 |
| 74 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.49928485 |
| 75 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.49800454 |
| 76 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.49754024 |
| 77 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.46626470 |
| 78 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.46190987 |
| 79 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.43837467 |
| 80 | Peroxisome_Homo sapiens_hsa04146 | 0.43636131 |
| 81 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.42462829 |
| 82 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.41982061 |
| 83 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.41907894 |
| 84 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.38365734 |
| 85 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.38307866 |
| 86 | Retinol metabolism_Homo sapiens_hsa00830 | 0.37754206 |
| 87 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.37135115 |
| 88 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.36376240 |
| 89 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.35479367 |
| 90 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.35261833 |
| 91 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.34734306 |
| 92 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.33013136 |
| 93 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.31992012 |
| 94 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.31866025 |
| 95 | Taste transduction_Homo sapiens_hsa04742 | 0.31088293 |
| 96 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.29300727 |
| 97 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.28565964 |
| 98 | Viral myocarditis_Homo sapiens_hsa05416 | 0.26651146 |
| 99 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.26482463 |
| 100 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.25970008 |

