

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 7.89679039 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 7.75682376 |
| 3 | regulation of hypersensitivity (GO:0002883) | 7.58040439 |
| 4 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 6.62330999 |
| 5 | positive regulation of mast cell degranulation (GO:0043306) | 6.62330999 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 6.57992675 |
| 7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.57992675 |
| 8 | positive regulation of mast cell activation (GO:0033005) | 5.81616603 |
| 9 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 5.57855880 |
| 10 | positive regulation of protein homodimerization activity (GO:0090073) | 5.43920195 |
| 11 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 5.40406764 |
| 12 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.28430955 |
| 13 | chaperone-mediated protein transport (GO:0072321) | 5.16708037 |
| 14 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 4.94536346 |
| 15 | platelet dense granule organization (GO:0060155) | 4.94380617 |
| 16 | respiratory electron transport chain (GO:0022904) | 4.66735805 |
| 17 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.62669964 |
| 18 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 4.62131446 |
| 19 | viral transcription (GO:0019083) | 4.60349899 |
| 20 | electron transport chain (GO:0022900) | 4.54008262 |
| 21 | protein maturation by protein folding (GO:0022417) | 4.52385356 |
| 22 | ribosomal small subunit assembly (GO:0000028) | 4.52379216 |
| 23 | positive regulation of leukocyte degranulation (GO:0043302) | 4.49696702 |
| 24 | translational termination (GO:0006415) | 4.41496046 |
| 25 | response to pheromone (GO:0019236) | 4.41351124 |
| 26 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.27081408 |
| 27 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.27081408 |
| 28 | NADH dehydrogenase complex assembly (GO:0010257) | 4.27081408 |
| 29 | negative regulation of heart rate (GO:0010459) | 4.26987397 |
| 30 | hepatocyte differentiation (GO:0070365) | 4.21143837 |
| 31 | monoamine transport (GO:0015844) | 4.19600139 |
| 32 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 4.17877050 |
| 33 | positive regulation of B cell mediated immunity (GO:0002714) | 4.17877050 |
| 34 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.08149026 |
| 35 | immunoglobulin mediated immune response (GO:0016064) | 4.05728417 |
| 36 | regulation of inflammatory response to antigenic stimulus (GO:0002861) | 4.05242826 |
| 37 | protein complex biogenesis (GO:0070271) | 4.01167848 |
| 38 | protein targeting to ER (GO:0045047) | 4.00605932 |
| 39 | cotranslational protein targeting to membrane (GO:0006613) | 3.98569312 |
| 40 | ribosomal large subunit biogenesis (GO:0042273) | 3.90144342 |
| 41 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.81760134 |
| 42 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.81154526 |
| 43 | proteasome assembly (GO:0043248) | 3.80848782 |
| 44 | ATP biosynthetic process (GO:0006754) | 3.79550974 |
| 45 | protein localization to endoplasmic reticulum (GO:0070972) | 3.79186650 |
| 46 | dopamine transport (GO:0015872) | 3.75194237 |
| 47 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 3.68773855 |
| 48 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 3.68773855 |
| 49 | B cell mediated immunity (GO:0019724) | 3.61464317 |
| 50 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.61415810 |
| 51 | translational elongation (GO:0006414) | 3.60263547 |
| 52 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.50888010 |
| 53 | GPI anchor biosynthetic process (GO:0006506) | 3.47653718 |
| 54 | viral life cycle (GO:0019058) | 3.45897139 |
| 55 | icosanoid secretion (GO:0032309) | 3.43819846 |
| 56 | arachidonic acid secretion (GO:0050482) | 3.43819846 |
| 57 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.38855870 |
| 58 | response to vitamin E (GO:0033197) | 3.32972641 |
| 59 | hydrogen ion transmembrane transport (GO:1902600) | 3.29270088 |
| 60 | cellular protein complex disassembly (GO:0043624) | 3.28659804 |
| 61 | regulation of mast cell activation (GO:0033003) | 3.20879482 |
| 62 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.20309720 |
| 63 | secondary heart field specification (GO:0003139) | 3.19125244 |
| 64 | heart field specification (GO:0003128) | 3.19125244 |
| 65 | maturation of SSU-rRNA (GO:0030490) | 3.17376954 |
| 66 | positive regulation of acute inflammatory response (GO:0002675) | 3.16608014 |
| 67 | translational initiation (GO:0006413) | 3.13410728 |
| 68 | GPI anchor metabolic process (GO:0006505) | 3.13048085 |
| 69 | regulation of mast cell degranulation (GO:0043304) | 3.12840121 |
| 70 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 3.12296934 |
| 71 | respiratory chain complex IV assembly (GO:0008535) | 3.11468697 |
| 72 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.11354506 |
| 73 | neutrophil activation involved in immune response (GO:0002283) | 3.06661755 |
| 74 | skeletal muscle tissue regeneration (GO:0043403) | 3.05467735 |
| 75 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.02383774 |
| 76 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.00203914 |
| 77 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 3.00041579 |
| 78 | regulation of growth of symbiont in host (GO:0044126) | 3.00041579 |
| 79 | negative regulation of growth of symbiont in host (GO:0044130) | 3.00041579 |
| 80 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 3.00041579 |
| 81 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.98205876 |
| 82 | galactose catabolic process (GO:0019388) | 2.96836876 |
| 83 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.94795172 |
| 84 | translation (GO:0006412) | 2.94454947 |
| 85 | neuronal action potential propagation (GO:0019227) | 2.93535591 |
| 86 | positive regulation of regulated secretory pathway (GO:1903307) | 2.91812819 |
| 87 | protein targeting to membrane (GO:0006612) | 2.89496340 |
| 88 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.89040692 |
| 89 | positive regulation of chemokine biosynthetic process (GO:0045080) | 2.86925287 |
| 90 | protein peptidyl-prolyl isomerization (GO:0000413) | 2.86117307 |
| 91 | regulation of chronic inflammatory response (GO:0002676) | 2.85666669 |
| 92 | aldehyde catabolic process (GO:0046185) | 2.80298999 |
| 93 | regulation of myeloid cell apoptotic process (GO:0033032) | 2.77795183 |
| 94 | proton transport (GO:0015992) | 2.77552738 |
| 95 | positive regulation of vesicle fusion (GO:0031340) | 2.76926178 |
| 96 | fatty acid derivative transport (GO:1901571) | 2.76773829 |
| 97 | icosanoid transport (GO:0071715) | 2.76773829 |
| 98 | viral mRNA export from host cell nucleus (GO:0046784) | 2.76264380 |
| 99 | negative regulation of acute inflammatory response (GO:0002674) | 2.76088295 |
| 100 | heart trabecula morphogenesis (GO:0061384) | 2.75876265 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.71977877 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 3.85193563 |
| 3 | TAF15_26573619_Chip-Seq_HEK293_Human | 3.78028778 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.43369979 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.17827393 |
| 6 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 3.05178411 |
| 7 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.91828654 |
| 8 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.83848709 |
| 9 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.77598356 |
| 10 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.49917114 |
| 11 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.43537946 |
| 12 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.33961980 |
| 13 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.18252617 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.08046499 |
| 15 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.05401097 |
| 16 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.05024282 |
| 17 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.04392587 |
| 18 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 2.03610656 |
| 19 | P300_19829295_ChIP-Seq_ESCs_Human | 2.03398505 |
| 20 | EWS_26573619_Chip-Seq_HEK293_Human | 2.00727188 |
| 21 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.98998158 |
| 22 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.93396061 |
| 23 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.78968475 |
| 24 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.75780907 |
| 25 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.69415958 |
| 26 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.66028181 |
| 27 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.63574867 |
| 28 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.63036855 |
| 29 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.63036855 |
| 30 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.61431830 |
| 31 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.56431883 |
| 32 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.52734381 |
| 33 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.51365382 |
| 34 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.48618008 |
| 35 | FUS_26573619_Chip-Seq_HEK293_Human | 1.48037634 |
| 36 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.46996805 |
| 37 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.46996805 |
| 38 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.45759110 |
| 39 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.45113072 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.42888912 |
| 41 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.39585802 |
| 42 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.39085630 |
| 43 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.38432185 |
| 44 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.36897289 |
| 45 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.36696625 |
| 46 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.36077543 |
| 47 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.35966927 |
| 48 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.35156584 |
| 49 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.31700795 |
| 50 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.28944669 |
| 51 | GATA3_26560356_Chip-Seq_TH2_Human | 1.27541428 |
| 52 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.24208533 |
| 53 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.19687590 |
| 54 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.16742158 |
| 55 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.16647112 |
| 56 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.16500890 |
| 57 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.16462130 |
| 58 | AR_20517297_ChIP-Seq_VCAP_Human | 1.16063442 |
| 59 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.15991265 |
| 60 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.15853412 |
| 61 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.15680852 |
| 62 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.14254748 |
| 63 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.13538063 |
| 64 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.12385465 |
| 65 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.12354415 |
| 66 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.12275084 |
| 67 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.11803282 |
| 68 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.11760037 |
| 69 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.08894476 |
| 70 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.08572243 |
| 71 | GATA3_26560356_Chip-Seq_TH1_Human | 1.05311361 |
| 72 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.04937976 |
| 73 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.04790202 |
| 74 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.04770954 |
| 75 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.04583800 |
| 76 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.04317612 |
| 77 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.03952316 |
| 78 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.02810574 |
| 79 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.02526432 |
| 80 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.02431485 |
| 81 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.01192275 |
| 82 | AR_25329375_ChIP-Seq_VCAP_Human | 1.00049338 |
| 83 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.99870852 |
| 84 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.99843163 |
| 85 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.95789819 |
| 86 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.95589679 |
| 87 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.94445785 |
| 88 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.93463114 |
| 89 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.93144838 |
| 90 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.92142579 |
| 91 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.91762400 |
| 92 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.91697161 |
| 93 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.91555179 |
| 94 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.91431149 |
| 95 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.91122017 |
| 96 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.90181608 |
| 97 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.89475365 |
| 98 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.89404613 |
| 99 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.89379416 |
| 100 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.89199360 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 4.38572679 |
| 2 | MP0009379_abnormal_foot_pigmentation | 4.17045844 |
| 3 | MP0004147_increased_porphyrin_level | 3.84372701 |
| 4 | MP0005671_abnormal_response_to | 3.01692417 |
| 5 | MP0006292_abnormal_olfactory_placode | 2.51955113 |
| 6 | MP0009333_abnormal_splenocyte_physiolog | 2.27077176 |
| 7 | MP0005367_renal/urinary_system_phenotyp | 2.26465643 |
| 8 | MP0000516_abnormal_urinary_system | 2.26465643 |
| 9 | MP0002234_abnormal_pharynx_morphology | 2.02282365 |
| 10 | MP0009785_altered_susceptibility_to | 1.98334310 |
| 11 | MP0008872_abnormal_physiological_respon | 1.97315746 |
| 12 | MP0000685_abnormal_immune_system | 1.94988931 |
| 13 | MP0005646_abnormal_pituitary_gland | 1.94061831 |
| 14 | MP0002163_abnormal_gland_morphology | 1.93052626 |
| 15 | MP0001800_abnormal_humoral_immune | 1.92846671 |
| 16 | MP0001873_stomach_inflammation | 1.90318284 |
| 17 | MP0008995_early_reproductive_senescence | 1.76358747 |
| 18 | MP0009764_decreased_sensitivity_to | 1.73039999 |
| 19 | MP0006036_abnormal_mitochondrial_physio | 1.68487088 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 1.66661671 |
| 21 | MP0001905_abnormal_dopamine_level | 1.61007615 |
| 22 | MP0003724_increased_susceptibility_to | 1.53533611 |
| 23 | MP0000372_irregular_coat_pigmentation | 1.53475157 |
| 24 | MP0005551_abnormal_eye_electrophysiolog | 1.53303383 |
| 25 | MP0002138_abnormal_hepatobiliary_system | 1.52050201 |
| 26 | MP0002102_abnormal_ear_morphology | 1.50145797 |
| 27 | MP0001986_abnormal_taste_sensitivity | 1.47367310 |
| 28 | MP0002736_abnormal_nociception_after | 1.45614005 |
| 29 | MP0005645_abnormal_hypothalamus_physiol | 1.41132945 |
| 30 | MP0000427_abnormal_hair_cycle | 1.38462502 |
| 31 | MP0005000_abnormal_immune_tolerance | 1.34285785 |
| 32 | MP0004381_abnormal_hair_follicle | 1.31089058 |
| 33 | MP0001765_abnormal_ion_homeostasis | 1.30905102 |
| 34 | MP0005387_immune_system_phenotype | 1.30721571 |
| 35 | MP0001790_abnormal_immune_system | 1.30721571 |
| 36 | MP0003950_abnormal_plasma_membrane | 1.30690830 |
| 37 | MP0002452_abnormal_antigen_presenting | 1.27752336 |
| 38 | MP0002837_dystrophic_cardiac_calcinosis | 1.25770735 |
| 39 | MP0004019_abnormal_vitamin_homeostasis | 1.25127790 |
| 40 | MP0006276_abnormal_autonomic_nervous | 1.24831216 |
| 41 | MP0002166_altered_tumor_susceptibility | 1.24193135 |
| 42 | MP0001919_abnormal_reproductive_system | 1.23261489 |
| 43 | MP0004145_abnormal_muscle_electrophysio | 1.21916819 |
| 44 | MP0001529_abnormal_vocalization | 1.21121379 |
| 45 | MP0003195_calcinosis | 1.18776782 |
| 46 | MP0001486_abnormal_startle_reflex | 1.16541133 |
| 47 | MP0003567_abnormal_fetal_cardiomyocyte | 1.16160106 |
| 48 | MP0003075_altered_response_to | 1.16009291 |
| 49 | MP0003011_delayed_dark_adaptation | 1.15834442 |
| 50 | MP0000647_abnormal_sebaceous_gland | 1.15196850 |
| 51 | MP0010155_abnormal_intestine_physiology | 1.09768785 |
| 52 | MP0005166_decreased_susceptibility_to | 1.09691544 |
| 53 | MP0002723_abnormal_immune_serum | 1.06382632 |
| 54 | MP0002277_abnormal_respiratory_mucosa | 1.05564693 |
| 55 | MP0002751_abnormal_autonomic_nervous | 1.05157912 |
| 56 | MP0000383_abnormal_hair_follicle | 1.04949305 |
| 57 | MP0005379_endocrine/exocrine_gland_phen | 1.04529817 |
| 58 | MP0005253_abnormal_eye_physiology | 1.03797055 |
| 59 | MP0009053_abnormal_anal_canal | 1.03203479 |
| 60 | MP0008875_abnormal_xenobiotic_pharmacok | 1.02915220 |
| 61 | MP0004142_abnormal_muscle_tone | 1.00489977 |
| 62 | MP0003436_decreased_susceptibility_to | 0.98868557 |
| 63 | MP0003638_abnormal_response/metabolism_ | 0.97383182 |
| 64 | MP0002090_abnormal_vision | 0.97075158 |
| 65 | MP0006072_abnormal_retinal_apoptosis | 0.96072938 |
| 66 | MP0005389_reproductive_system_phenotype | 0.95704341 |
| 67 | MP0002006_tumorigenesis | 0.95556312 |
| 68 | MP0005636_abnormal_mineral_homeostasis | 0.92236816 |
| 69 | MP0003866_abnormal_defecation | 0.91812988 |
| 70 | MP0002735_abnormal_chemical_nociception | 0.91692187 |
| 71 | MP0000569_abnormal_digit_pigmentation | 0.91134127 |
| 72 | MP0001968_abnormal_touch/_nociception | 0.90497283 |
| 73 | MP0009046_muscle_twitch | 0.89728668 |
| 74 | MP0008961_abnormal_basal_metabolism | 0.88282291 |
| 75 | MP0000343_altered_response_to | 0.88157272 |
| 76 | MP0005025_abnormal_response_to | 0.87674182 |
| 77 | MP0002420_abnormal_adaptive_immunity | 0.86988595 |
| 78 | MP0001664_abnormal_digestion | 0.85769347 |
| 79 | MP0003252_abnormal_bile_duct | 0.84960885 |
| 80 | MP0009745_abnormal_behavioral_response | 0.84629698 |
| 81 | MP0001819_abnormal_immune_cell | 0.84219873 |
| 82 | MP0004085_abnormal_heartbeat | 0.83957352 |
| 83 | MP0006054_spinal_hemorrhage | 0.83129624 |
| 84 | MP0000537_abnormal_urethra_morphology | 0.82607079 |
| 85 | MP0002282_abnormal_trachea_morphology | 0.80904817 |
| 86 | MP0000230_abnormal_systemic_arterial | 0.79621288 |
| 87 | MP0006035_abnormal_mitochondrial_morpho | 0.78823103 |
| 88 | MP0002734_abnormal_mechanical_nocicepti | 0.78556841 |
| 89 | MP0001970_abnormal_pain_threshold | 0.77985116 |
| 90 | MP0004084_abnormal_cardiac_muscle | 0.77913979 |
| 91 | MP0002272_abnormal_nervous_system | 0.77167579 |
| 92 | MP0006082_CNS_inflammation | 0.76830014 |
| 93 | MP0003938_abnormal_ear_development | 0.76303968 |
| 94 | MP0005647_abnormal_sex_gland | 0.75796207 |
| 95 | MP0001845_abnormal_inflammatory_respons | 0.74997135 |
| 96 | MP0002160_abnormal_reproductive_system | 0.74850722 |
| 97 | MP0001286_abnormal_eye_development | 0.73334834 |
| 98 | MP0008058_abnormal_DNA_repair | 0.72725417 |
| 99 | MP0003186_abnormal_redox_activity | 0.72581961 |
| 100 | MP0005377_hearing/vestibular/ear_phenot | 0.71600331 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 6.39485591 |
| 2 | Acute encephalopathy (HP:0006846) | 5.66199774 |
| 3 | Mitochondrial inheritance (HP:0001427) | 5.49568771 |
| 4 | Progressive macrocephaly (HP:0004481) | 5.37903756 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.36510162 |
| 6 | Increased CSF lactate (HP:0002490) | 5.22910850 |
| 7 | Lipid accumulation in hepatocytes (HP:0006561) | 4.97427025 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 4.96024943 |
| 9 | Hypothermia (HP:0002045) | 4.61106634 |
| 10 | Hepatocellular necrosis (HP:0001404) | 4.56943967 |
| 11 | Exertional dyspnea (HP:0002875) | 4.27997788 |
| 12 | Cerebral edema (HP:0002181) | 4.21027209 |
| 13 | Congenital, generalized hypertrichosis (HP:0004540) | 4.08667920 |
| 14 | Renal Fanconi syndrome (HP:0001994) | 3.74160809 |
| 15 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.63567289 |
| 16 | Hepatic necrosis (HP:0002605) | 3.62708177 |
| 17 | Large eyes (HP:0001090) | 3.31183107 |
| 18 | Chronic sinusitis (HP:0011109) | 3.26138669 |
| 19 | Leukodystrophy (HP:0002415) | 3.25228498 |
| 20 | Azoospermia (HP:0000027) | 3.09424580 |
| 21 | Premature ovarian failure (HP:0008209) | 3.07938895 |
| 22 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.99024527 |
| 23 | Sensory axonal neuropathy (HP:0003390) | 2.78320537 |
| 24 | Optic disc pallor (HP:0000543) | 2.69685422 |
| 25 | Exercise intolerance (HP:0003546) | 2.69063962 |
| 26 | Abnormality of renal resorption (HP:0011038) | 2.67623488 |
| 27 | Supernumerary spleens (HP:0009799) | 2.65061881 |
| 28 | Reduced antithrombin III activity (HP:0001976) | 2.59832959 |
| 29 | Concave nail (HP:0001598) | 2.57836901 |
| 30 | Hypoalphalipoproteinemia (HP:0003233) | 2.57021413 |
| 31 | Increased intramyocellular lipid droplets (HP:0012240) | 2.52543395 |
| 32 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.43906598 |
| 33 | Absent/shortened dynein arms (HP:0200106) | 2.43906598 |
| 34 | Testicular atrophy (HP:0000029) | 2.43364519 |
| 35 | Respiratory failure (HP:0002878) | 2.38783541 |
| 36 | CNS demyelination (HP:0007305) | 2.37263707 |
| 37 | Hyperphosphaturia (HP:0003109) | 2.32857484 |
| 38 | Febrile seizures (HP:0002373) | 2.31898360 |
| 39 | Increased muscle lipid content (HP:0009058) | 2.31837992 |
| 40 | Pulmonary infiltrates (HP:0002113) | 2.31502535 |
| 41 | Poor head control (HP:0002421) | 2.27663747 |
| 42 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.26417805 |
| 43 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.21664256 |
| 44 | Large for gestational age (HP:0001520) | 2.19386921 |
| 45 | Constricted visual fields (HP:0001133) | 2.17137870 |
| 46 | Increased serum lactate (HP:0002151) | 2.16579922 |
| 47 | Rib fusion (HP:0000902) | 2.14613714 |
| 48 | Abnormal ciliary motility (HP:0012262) | 2.14136047 |
| 49 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.12671829 |
| 50 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.12671829 |
| 51 | Reticulocytopenia (HP:0001896) | 2.07165735 |
| 52 | Respiratory difficulties (HP:0002880) | 2.05572065 |
| 53 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.04709009 |
| 54 | Arthropathy (HP:0003040) | 2.04261379 |
| 55 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.01818611 |
| 56 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.01818611 |
| 57 | Glycosuria (HP:0003076) | 2.00521996 |
| 58 | Abnormality of urine glucose concentration (HP:0011016) | 2.00521996 |
| 59 | Abnormal spermatogenesis (HP:0008669) | 1.99848101 |
| 60 | Pallor (HP:0000980) | 1.98838998 |
| 61 | Abnormality of macular pigmentation (HP:0008002) | 1.98268149 |
| 62 | Tetany (HP:0001281) | 1.97936019 |
| 63 | Absent hand (HP:0004050) | 1.97610545 |
| 64 | Gangrene (HP:0100758) | 1.97242092 |
| 65 | Woolly hair (HP:0002224) | 1.96947363 |
| 66 | Ureteral stenosis (HP:0000071) | 1.96038428 |
| 67 | Intestinal atresia (HP:0011100) | 1.92610121 |
| 68 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.92463340 |
| 69 | Renal tubular dysfunction (HP:0000124) | 1.90565212 |
| 70 | Oral leukoplakia (HP:0002745) | 1.89859915 |
| 71 | Lethargy (HP:0001254) | 1.89595189 |
| 72 | Hypomagnesemia (HP:0002917) | 1.86417860 |
| 73 | Ureteral obstruction (HP:0006000) | 1.84961831 |
| 74 | Chronic bronchitis (HP:0004469) | 1.84666410 |
| 75 | Alveolar cell carcinoma (HP:0006519) | 1.84146044 |
| 76 | Volvulus (HP:0002580) | 1.82854724 |
| 77 | Macrocytic anemia (HP:0001972) | 1.81638443 |
| 78 | Symptomatic seizures (HP:0011145) | 1.80734241 |
| 79 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.79975172 |
| 80 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.77773909 |
| 81 | Lactic acidosis (HP:0003128) | 1.77709909 |
| 82 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.76674630 |
| 83 | Abnormal urine phosphate concentration (HP:0012599) | 1.76606190 |
| 84 | Tongue fasciculations (HP:0001308) | 1.76338001 |
| 85 | Onycholysis (HP:0001806) | 1.75705985 |
| 86 | Abnormality of the prostate (HP:0008775) | 1.75134204 |
| 87 | Type II lissencephaly (HP:0007260) | 1.71526138 |
| 88 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.69431160 |
| 89 | Abnormality of dental color (HP:0011073) | 1.69230845 |
| 90 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.69105376 |
| 91 | Short chin (HP:0000331) | 1.67794912 |
| 92 | Myotonia (HP:0002486) | 1.66952530 |
| 93 | X-linked dominant inheritance (HP:0001423) | 1.66775607 |
| 94 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.65782925 |
| 95 | Pancreatic cysts (HP:0001737) | 1.64939452 |
| 96 | Polyneuropathy (HP:0001271) | 1.62508623 |
| 97 | Parakeratosis (HP:0001036) | 1.62361805 |
| 98 | Short tibia (HP:0005736) | 1.61524706 |
| 99 | Abnormality of the pleura (HP:0002103) | 1.61450998 |
| 100 | Resting tremor (HP:0002322) | 1.60967346 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K12 | 5.79025031 |
| 2 | BMPR2 | 4.45126032 |
| 3 | STK16 | 3.43083507 |
| 4 | MYLK | 3.05883104 |
| 5 | ILK | 2.78085365 |
| 6 | ERBB3 | 2.74616201 |
| 7 | TLK1 | 2.68941610 |
| 8 | BLK | 2.64844199 |
| 9 | TAOK3 | 2.52815635 |
| 10 | CDK19 | 2.43192025 |
| 11 | DAPK1 | 2.38449320 |
| 12 | STK38L | 2.19866666 |
| 13 | TRPM7 | 2.09101726 |
| 14 | TRIM28 | 2.00070394 |
| 15 | DAPK3 | 1.95856437 |
| 16 | SCYL2 | 1.92216873 |
| 17 | DAPK2 | 1.72792308 |
| 18 | PIK3CG | 1.60232403 |
| 19 | MKNK2 | 1.56141283 |
| 20 | ACVR1B | 1.54705662 |
| 21 | RIPK4 | 1.47774598 |
| 22 | NME1 | 1.47294931 |
| 23 | GRK1 | 1.47196312 |
| 24 | TIE1 | 1.38884997 |
| 25 | BUB1 | 1.37155212 |
| 26 | STK39 | 1.34679607 |
| 27 | MKNK1 | 1.34578590 |
| 28 | OXSR1 | 1.28120662 |
| 29 | SIK3 | 1.26268882 |
| 30 | GRK6 | 1.25929824 |
| 31 | FRK | 1.25409903 |
| 32 | CDK8 | 1.23878953 |
| 33 | MAP4K2 | 1.18468009 |
| 34 | ERBB4 | 1.06760280 |
| 35 | MATK | 1.03298505 |
| 36 | MAP4K1 | 1.01024450 |
| 37 | EIF2AK3 | 0.95622747 |
| 38 | PAK4 | 0.93635000 |
| 39 | MAPKAPK3 | 0.90698723 |
| 40 | LYN | 0.84932121 |
| 41 | CSF1R | 0.84917301 |
| 42 | GRK5 | 0.82869390 |
| 43 | ROCK1 | 0.77463826 |
| 44 | TEC | 0.73785717 |
| 45 | INSRR | 0.73585345 |
| 46 | PRKCG | 0.72642078 |
| 47 | ERBB2 | 0.72571674 |
| 48 | SYK | 0.68839900 |
| 49 | AURKB | 0.68574746 |
| 50 | PRKCE | 0.67849812 |
| 51 | MST4 | 0.67752284 |
| 52 | PRKD3 | 0.67369500 |
| 53 | OBSCN | 0.62363604 |
| 54 | WNK3 | 0.61959916 |
| 55 | PRKG1 | 0.61736991 |
| 56 | TXK | 0.61698491 |
| 57 | ADRBK2 | 0.61134692 |
| 58 | IKBKB | 0.60148428 |
| 59 | VRK2 | 0.59861155 |
| 60 | MAPK13 | 0.57936775 |
| 61 | KIT | 0.57329412 |
| 62 | IGF1R | 0.56413200 |
| 63 | PKN1 | 0.55995295 |
| 64 | PHKG2 | 0.55677106 |
| 65 | PHKG1 | 0.55677106 |
| 66 | EIF2AK2 | 0.55603515 |
| 67 | EPHB2 | 0.55459811 |
| 68 | BMPR1B | 0.53067835 |
| 69 | CAMKK2 | 0.51380150 |
| 70 | FLT3 | 0.49561086 |
| 71 | MARK3 | 0.48398920 |
| 72 | EGFR | 0.48263411 |
| 73 | WNK4 | 0.46664959 |
| 74 | GRK7 | 0.46581058 |
| 75 | ROCK2 | 0.46233863 |
| 76 | STK24 | 0.45248962 |
| 77 | NUAK1 | 0.40855277 |
| 78 | ABL1 | 0.40680017 |
| 79 | FES | 0.38919267 |
| 80 | CAMK2D | 0.37495467 |
| 81 | PRKACA | 0.37432080 |
| 82 | PASK | 0.35688484 |
| 83 | VRK1 | 0.35535745 |
| 84 | PRKACB | 0.34792341 |
| 85 | PRKCA | 0.34736973 |
| 86 | CSNK2A2 | 0.34391377 |
| 87 | CAMK2G | 0.34198621 |
| 88 | CAMK2B | 0.33464932 |
| 89 | DYRK2 | 0.31926731 |
| 90 | PRKACG | 0.31608561 |
| 91 | LCK | 0.31341495 |
| 92 | HCK | 0.31094558 |
| 93 | STK3 | 0.30234079 |
| 94 | PRKCB | 0.29389174 |
| 95 | CAMK2A | 0.28738130 |
| 96 | PRKCD | 0.28330316 |
| 97 | MUSK | 0.27809158 |
| 98 | IRAK1 | 0.25823977 |
| 99 | SIK2 | 0.25555128 |
| 100 | JAK1 | 0.25133282 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 6.58078177 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 3.95408004 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.81239150 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.80530414 |
| 5 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 3.68198661 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.68069493 |
| 7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.45939436 |
| 8 | Ribosome_Homo sapiens_hsa03010 | 3.21658274 |
| 9 | Parkinsons disease_Homo sapiens_hsa05012 | 3.17965935 |
| 10 | Proteasome_Homo sapiens_hsa03050 | 2.70781842 |
| 11 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.24326659 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 2.23311422 |
| 13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.18461252 |
| 14 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.03208832 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.96388720 |
| 16 | Huntingtons disease_Homo sapiens_hsa05016 | 1.95128147 |
| 17 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.91042624 |
| 18 | Protein export_Homo sapiens_hsa03060 | 1.82712628 |
| 19 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.77414793 |
| 20 | Viral myocarditis_Homo sapiens_hsa05416 | 1.77369198 |
| 21 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.75102807 |
| 22 | Leishmaniasis_Homo sapiens_hsa05140 | 1.48741220 |
| 23 | Homologous recombination_Homo sapiens_hsa03440 | 1.34642544 |
| 24 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.32315539 |
| 25 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.31758495 |
| 26 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.03029295 |
| 27 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.98777104 |
| 28 | Tuberculosis_Homo sapiens_hsa05152 | 0.89747874 |
| 29 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.89647803 |
| 30 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.86739219 |
| 31 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.85749847 |
| 32 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.85354825 |
| 33 | Basal transcription factors_Homo sapiens_hsa03022 | 0.83063361 |
| 34 | Olfactory transduction_Homo sapiens_hsa04740 | 0.77901019 |
| 35 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.76145006 |
| 36 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.73802977 |
| 37 | Legionellosis_Homo sapiens_hsa05134 | 0.72248026 |
| 38 | RNA degradation_Homo sapiens_hsa03018 | 0.71613377 |
| 39 | Phototransduction_Homo sapiens_hsa04744 | 0.70951711 |
| 40 | Phagosome_Homo sapiens_hsa04145 | 0.67924091 |
| 41 | RNA polymerase_Homo sapiens_hsa03020 | 0.64788331 |
| 42 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.60707543 |
| 43 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.59082326 |
| 44 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.56890661 |
| 45 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.53021435 |
| 46 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.52774934 |
| 47 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.52000605 |
| 48 | Influenza A_Homo sapiens_hsa05164 | 0.48751506 |
| 49 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.47415820 |
| 50 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.47172604 |
| 51 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.46855510 |
| 52 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.45403444 |
| 53 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.44742345 |
| 54 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.42799956 |
| 55 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.42263025 |
| 56 | RNA transport_Homo sapiens_hsa03013 | 0.40926059 |
| 57 | Retinol metabolism_Homo sapiens_hsa00830 | 0.39125718 |
| 58 | Nicotine addiction_Homo sapiens_hsa05033 | 0.37572714 |
| 59 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.36470378 |
| 60 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.36133293 |
| 61 | Base excision repair_Homo sapiens_hsa03410 | 0.33801395 |
| 62 | Spliceosome_Homo sapiens_hsa03040 | 0.32981357 |
| 63 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.32451877 |
| 64 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.32189548 |
| 65 | Taste transduction_Homo sapiens_hsa04742 | 0.32143621 |
| 66 | Salivary secretion_Homo sapiens_hsa04970 | 0.30880314 |
| 67 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.29898547 |
| 68 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.28714581 |
| 69 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.28177805 |
| 70 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.28032720 |
| 71 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.27721169 |
| 72 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.27554097 |
| 73 | Morphine addiction_Homo sapiens_hsa05032 | 0.27281839 |
| 74 | Purine metabolism_Homo sapiens_hsa00230 | 0.27070535 |
| 75 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.20335110 |
| 76 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.20004030 |
| 77 | Metabolic pathways_Homo sapiens_hsa01100 | 0.19776258 |
| 78 | Peroxisome_Homo sapiens_hsa04146 | 0.19562552 |
| 79 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.19173461 |
| 80 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.17592299 |
| 81 | Galactose metabolism_Homo sapiens_hsa00052 | 0.16906527 |
| 82 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.16406205 |
| 83 | Mismatch repair_Homo sapiens_hsa03430 | 0.16290740 |
| 84 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.15769780 |
| 85 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.14319315 |
| 86 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.14212927 |
| 87 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.13420677 |
| 88 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.11806101 |
| 89 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.10736730 |
| 90 | GABAergic synapse_Homo sapiens_hsa04727 | 0.10631323 |
| 91 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.10059149 |
| 92 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.08684622 |
| 93 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.08577583 |
| 94 | DNA replication_Homo sapiens_hsa03030 | 0.08400612 |
| 95 | Circadian entrainment_Homo sapiens_hsa04713 | 0.07278526 |
| 96 | Malaria_Homo sapiens_hsa05144 | 0.06920349 |
| 97 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.06276294 |
| 98 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.05874047 |
| 99 | Pertussis_Homo sapiens_hsa05133 | 0.05115137 |
| 100 | Salmonella infection_Homo sapiens_hsa05132 | 0.04867298 |

