

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | immunoglobulin mediated immune response (GO:0016064) | 6.70509773 |
| 2 | antigen processing and presentation of endogenous antigen (GO:0019883) | 6.02881141 |
| 3 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.71069751 |
| 4 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.60373904 |
| 5 | B cell receptor signaling pathway (GO:0050853) | 5.35567719 |
| 6 | B cell mediated immunity (GO:0019724) | 5.32319377 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.30671995 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.30671995 |
| 9 | modulation by symbiont of host immune response (GO:0052553) | 5.30671995 |
| 10 | positive regulation by symbiont of host defense response (GO:0052509) | 5.30671995 |
| 11 | modulation by symbiont of host defense response (GO:0052031) | 5.30671995 |
| 12 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.30671995 |
| 13 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.29854159 |
| 14 | interferon-gamma-mediated signaling pathway (GO:0060333) | 5.10190206 |
| 15 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 5.07540484 |
| 16 | detection of bacterium (GO:0016045) | 4.94922390 |
| 17 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.90309142 |
| 18 | macrophage activation involved in immune response (GO:0002281) | 4.87949591 |
| 19 | positive thymic T cell selection (GO:0045059) | 4.81421916 |
| 20 | detection of other organism (GO:0098543) | 4.78708781 |
| 21 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.78349638 |
| 22 | neutrophil activation involved in immune response (GO:0002283) | 4.68078192 |
| 23 | regulation of antigen processing and presentation (GO:0002577) | 4.66145984 |
| 24 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 4.64653634 |
| 25 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.62815966 |
| 26 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.60119140 |
| 27 | negative regulation of cell killing (GO:0031342) | 4.60119140 |
| 28 | positive regulation of type 2 immune response (GO:0002830) | 4.24065131 |
| 29 | positive regulation of antigen processing and presentation (GO:0002579) | 4.23196312 |
| 30 | positive regulation of mast cell activation (GO:0033005) | 4.15474378 |
| 31 | type I interferon signaling pathway (GO:0060337) | 4.13789250 |
| 32 | cellular response to type I interferon (GO:0071357) | 4.13789250 |
| 33 | defense response to protozoan (GO:0042832) | 4.12558882 |
| 34 | positive regulation of B cell differentiation (GO:0045579) | 4.09280615 |
| 35 | response to type I interferon (GO:0034340) | 4.08374570 |
| 36 | response to peptidoglycan (GO:0032494) | 4.07970326 |
| 37 | positive regulation of mast cell degranulation (GO:0043306) | 4.07900306 |
| 38 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 4.07900306 |
| 39 | regulation of B cell differentiation (GO:0045577) | 4.01690292 |
| 40 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.92109951 |
| 41 | T cell costimulation (GO:0031295) | 3.92102141 |
| 42 | regulation of gamma-delta T cell activation (GO:0046643) | 3.90568510 |
| 43 | microglial cell activation (GO:0001774) | 3.86514184 |
| 44 | lymphocyte costimulation (GO:0031294) | 3.86489019 |
| 45 | cellular response to interferon-gamma (GO:0071346) | 3.85314488 |
| 46 | detection of external biotic stimulus (GO:0098581) | 3.83115575 |
| 47 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.81576634 |
| 48 | response to host immune response (GO:0052572) | 3.81576634 |
| 49 | negative thymic T cell selection (GO:0045060) | 3.81317551 |
| 50 | regulation of mast cell degranulation (GO:0043304) | 3.75825745 |
| 51 | positive T cell selection (GO:0043368) | 3.69225418 |
| 52 | myeloid cell activation involved in immune response (GO:0002275) | 3.66221765 |
| 53 | positive regulation of interferon-alpha production (GO:0032727) | 3.65041460 |
| 54 | response to protozoan (GO:0001562) | 3.61194722 |
| 55 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.61032032 |
| 56 | B cell proliferation (GO:0042100) | 3.56987573 |
| 57 | regulation of mast cell activation (GO:0033003) | 3.56903659 |
| 58 | T cell selection (GO:0045058) | 3.56373243 |
| 59 | negative T cell selection (GO:0043383) | 3.54475198 |
| 60 | thymic T cell selection (GO:0045061) | 3.52663631 |
| 61 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.48556488 |
| 62 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.48083730 |
| 63 | response to host (GO:0075136) | 3.47127507 |
| 64 | response to host defenses (GO:0052200) | 3.47127507 |
| 65 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.47127507 |
| 66 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.46203345 |
| 67 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.43911417 |
| 68 | response to interferon-gamma (GO:0034341) | 3.43821484 |
| 69 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.43061243 |
| 70 | regulation of hypersensitivity (GO:0002883) | 3.42049203 |
| 71 | regulation of interferon-alpha production (GO:0032647) | 3.40263053 |
| 72 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.36512451 |
| 73 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.34807137 |
| 74 | NIK/NF-kappaB signaling (GO:0038061) | 3.34345398 |
| 75 | detection of biotic stimulus (GO:0009595) | 3.32961076 |
| 76 | regulation of type 2 immune response (GO:0002828) | 3.31861456 |
| 77 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.30567561 |
| 78 | regulation of T cell tolerance induction (GO:0002664) | 3.30396991 |
| 79 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.28770785 |
| 80 | respiratory burst (GO:0045730) | 3.28490798 |
| 81 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.27051280 |
| 82 | B cell homeostasis (GO:0001782) | 3.25130565 |
| 83 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.22282299 |
| 84 | macrophage activation (GO:0042116) | 3.18630856 |
| 85 | regulation of tolerance induction (GO:0002643) | 3.13152759 |
| 86 | germinal center formation (GO:0002467) | 3.13040646 |
| 87 | neutrophil activation (GO:0042119) | 3.11736248 |
| 88 | regulation of germinal center formation (GO:0002634) | 3.11433936 |
| 89 | positive regulation of B cell proliferation (GO:0030890) | 3.09883422 |
| 90 | T-helper 1 type immune response (GO:0042088) | 3.08871881 |
| 91 | T cell migration (GO:0072678) | 3.08721729 |
| 92 | cellular extravasation (GO:0045123) | 3.07409345 |
| 93 | negative regulation of interleukin-12 production (GO:0032695) | 3.06811978 |
| 94 | negative regulation of T cell mediated immunity (GO:0002710) | 3.06778973 |
| 95 | regulation of B cell proliferation (GO:0030888) | 3.06552886 |
| 96 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli | 3.06039281 |
| 97 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.05290260 |
| 98 | positive regulation of B cell activation (GO:0050871) | 3.03590096 |
| 99 | regulation of MHC class I biosynthetic process (GO:0045343) | 3.02612927 |
| 100 | regulation of leukocyte degranulation (GO:0043300) | 3.00969933 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 7.87678466 |
| 2 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.94338621 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.39162338 |
| 4 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.90343067 |
| 5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.47565421 |
| 6 | MYC_22102868_ChIP-Seq_BL_Human | 3.40803588 |
| 7 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 3.36666457 |
| 8 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.35976356 |
| 9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.23085446 |
| 10 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.20829748 |
| 11 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.19463388 |
| 12 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.16821670 |
| 13 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.05987557 |
| 14 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.86814593 |
| 15 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.76812325 |
| 16 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.76795087 |
| 17 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.63829339 |
| 18 | MYB_26560356_Chip-Seq_TH2_Human | 2.55568476 |
| 19 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.51100054 |
| 20 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.43105272 |
| 21 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.38676071 |
| 22 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.37998296 |
| 23 | * MAF_26560356_Chip-Seq_TH1_Human | 2.34328498 |
| 24 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.28047182 |
| 25 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.23282258 |
| 26 | SPI1_23127762_ChIP-Seq_K562_Human | 2.20763186 |
| 27 | MYB_26560356_Chip-Seq_TH1_Human | 2.19135020 |
| 28 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.16272172 |
| 29 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.15528213 |
| 30 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.08502795 |
| 31 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.08342166 |
| 32 | UTX_26944678_Chip-Seq_JUKART_Human | 2.04106528 |
| 33 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.01681557 |
| 34 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.97337436 |
| 35 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.92241438 |
| 36 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.92228957 |
| 37 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.86081223 |
| 38 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.84027197 |
| 39 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.77475799 |
| 40 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.76976629 |
| 41 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.75188650 |
| 42 | MAF_26560356_Chip-Seq_TH2_Human | 1.69013978 |
| 43 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.68484722 |
| 44 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.67957698 |
| 45 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.54705146 |
| 46 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.51007011 |
| 47 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.49409813 |
| 48 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.41660642 |
| 49 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.39625145 |
| 50 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.38790568 |
| 51 | GATA3_26560356_Chip-Seq_TH2_Human | 1.38649662 |
| 52 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.35485462 |
| 53 | * VDR_24787735_ChIP-Seq_THP-1_Human | 1.33297335 |
| 54 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.33278173 |
| 55 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.30501168 |
| 56 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.30436059 |
| 57 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.29834233 |
| 58 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.29584934 |
| 59 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.29211642 |
| 60 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.26467658 |
| 61 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.26117548 |
| 62 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.25504467 |
| 63 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.24856869 |
| 64 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.22444146 |
| 65 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.22144586 |
| 66 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.20727911 |
| 67 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.19934958 |
| 68 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.18861051 |
| 69 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.16394553 |
| 70 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.15134208 |
| 71 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.14990573 |
| 72 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14493264 |
| 73 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.13140702 |
| 74 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.12322377 |
| 75 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.12322314 |
| 76 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.11747020 |
| 77 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.10496942 |
| 78 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.09858562 |
| 79 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.09088025 |
| 80 | * BCOR_27268052_Chip-Seq_Bcells_Human | 1.08848243 |
| 81 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.08073389 |
| 82 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.00968727 |
| 83 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.97473683 |
| 84 | GATA1_22025678_ChIP-Seq_K562_Human | 0.96533165 |
| 85 | * P300_27268052_Chip-Seq_Bcells_Human | 0.94604096 |
| 86 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.94585914 |
| 87 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92304303 |
| 88 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.88596820 |
| 89 | * SPI1_20517297_ChIP-Seq_HL60_Human | 0.87383934 |
| 90 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.86644405 |
| 91 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.85841945 |
| 92 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.84811729 |
| 93 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.79354042 |
| 94 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.78090447 |
| 95 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.76656396 |
| 96 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.76254768 |
| 97 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.76145997 |
| 98 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.75414895 |
| 99 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.74606110 |
| 100 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.74546504 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 5.97279370 |
| 2 | MP0001800_abnormal_humoral_immune | 3.96722147 |
| 3 | MP0005671_abnormal_response_to | 3.83023436 |
| 4 | MP0001790_abnormal_immune_system | 3.67450802 |
| 5 | MP0005387_immune_system_phenotype | 3.67450802 |
| 6 | MP0000685_abnormal_immune_system | 3.64828678 |
| 7 | MP0003303_peritoneal_inflammation | 3.46787308 |
| 8 | MP0005000_abnormal_immune_tolerance | 3.35456725 |
| 9 | MP0003436_decreased_susceptibility_to | 3.30201469 |
| 10 | MP0002452_abnormal_antigen_presenting | 3.21825419 |
| 11 | MP0003724_increased_susceptibility_to | 3.10845104 |
| 12 | MP0002723_abnormal_immune_serum | 3.05937456 |
| 13 | MP0009785_altered_susceptibility_to | 2.96661222 |
| 14 | MP0005025_abnormal_response_to | 2.88038070 |
| 15 | MP0002420_abnormal_adaptive_immunity | 2.85516978 |
| 16 | MP0001819_abnormal_immune_cell | 2.84971997 |
| 17 | MP0002419_abnormal_innate_immunity | 2.77899493 |
| 18 | MP0003763_abnormal_thymus_physiology | 2.55594099 |
| 19 | MP0002148_abnormal_hypersensitivity_rea | 2.45287011 |
| 20 | MP0002398_abnormal_bone_marrow | 2.31444647 |
| 21 | MP0006082_CNS_inflammation | 2.27733844 |
| 22 | MP0000716_abnormal_immune_system | 2.22298921 |
| 23 | MP0003183_abnormal_peptide_metabolism | 2.05133696 |
| 24 | MP0002166_altered_tumor_susceptibility | 2.05010752 |
| 25 | MP0010155_abnormal_intestine_physiology | 2.00632083 |
| 26 | MP0005464_abnormal_platelet_physiology | 1.97085532 |
| 27 | MP0002138_abnormal_hepatobiliary_system | 1.96852998 |
| 28 | MP0000689_abnormal_spleen_morphology | 1.92938828 |
| 29 | MP0002405_respiratory_system_inflammati | 1.89992365 |
| 30 | MP0001845_abnormal_inflammatory_respons | 1.83156256 |
| 31 | MP0002429_abnormal_blood_cell | 1.77445343 |
| 32 | MP0003300_gastrointestinal_ulcer | 1.76228275 |
| 33 | MP0001873_stomach_inflammation | 1.70661603 |
| 34 | MP0002722_abnormal_immune_system | 1.68542493 |
| 35 | MP0003172_abnormal_lysosome_physiology | 1.67909687 |
| 36 | MP0005310_abnormal_salivary_gland | 1.67245954 |
| 37 | MP0002396_abnormal_hematopoietic_system | 1.65180936 |
| 38 | MP0003866_abnormal_defecation | 1.56509523 |
| 39 | MP0009333_abnormal_splenocyte_physiolog | 1.55444105 |
| 40 | MP0008469_abnormal_protein_level | 1.49015192 |
| 41 | MP0000465_gastrointestinal_hemorrhage | 1.47160113 |
| 42 | MP0001533_abnormal_skeleton_physiology | 1.46456629 |
| 43 | MP0005451_abnormal_body_composition | 1.42099290 |
| 44 | MP0001853_heart_inflammation | 1.41691069 |
| 45 | MP0004947_skin_inflammation | 1.38632324 |
| 46 | MP0008260_abnormal_autophagy | 1.33735823 |
| 47 | MP0000703_abnormal_thymus_morphology | 1.33423026 |
| 48 | MP0002006_tumorigenesis | 1.30265781 |
| 49 | MP0009764_decreased_sensitivity_to | 1.26054837 |
| 50 | MP0001986_abnormal_taste_sensitivity | 1.24502907 |
| 51 | MP0003191_abnormal_cellular_cholesterol | 1.19299879 |
| 52 | MP0005166_decreased_susceptibility_to | 1.17977638 |
| 53 | MP0005075_abnormal_melanosome_morpholog | 1.16257916 |
| 54 | MP0003075_altered_response_to | 1.12448670 |
| 55 | MP0000858_altered_metastatic_potential | 1.11186019 |
| 56 | MP0002132_abnormal_respiratory_system | 1.08522655 |
| 57 | MP0002009_preneoplasia | 1.04261083 |
| 58 | MP0001348_abnormal_lacrimal_gland | 0.99773476 |
| 59 | MP0005397_hematopoietic_system_phenotyp | 0.94105868 |
| 60 | MP0001545_abnormal_hematopoietic_system | 0.94105868 |
| 61 | MP0001663_abnormal_digestive_system | 0.93101932 |
| 62 | MP0009278_abnormal_bone_marrow | 0.92921779 |
| 63 | MP0002998_abnormal_bone_remodeling | 0.91629594 |
| 64 | MP0009763_increased_sensitivity_to | 0.84705569 |
| 65 | MP0003828_pulmonary_edema | 0.83571287 |
| 66 | MP0004883_abnormal_blood_vessel | 0.82541823 |
| 67 | MP0003806_abnormal_nucleotide_metabolis | 0.82195958 |
| 68 | MP0005058_abnormal_lysosome_morphology | 0.81702286 |
| 69 | MP0001851_eye_inflammation | 0.81272128 |
| 70 | MP0004381_abnormal_hair_follicle | 0.78436019 |
| 71 | MP0000490_abnormal_crypts_of | 0.75888005 |
| 72 | MP0003045_fibrosis | 0.75496562 |
| 73 | MP0004510_myositis | 0.74588927 |
| 74 | MP0000249_abnormal_blood_vessel | 0.72215601 |
| 75 | MP0000015_abnormal_ear_pigmentation | 0.68864336 |
| 76 | MP0004808_abnormal_hematopoietic_stem | 0.68830288 |
| 77 | MP0002019_abnormal_tumor_incidence | 0.67610556 |
| 78 | MP0002933_joint_inflammation | 0.65806903 |
| 79 | MP0003690_abnormal_glial_cell | 0.65339830 |
| 80 | MP0003252_abnormal_bile_duct | 0.64846429 |
| 81 | MP0000343_altered_response_to | 0.60969601 |
| 82 | MP0003091_abnormal_cell_migration | 0.60748171 |
| 83 | MP0003448_altered_tumor_morphology | 0.59083692 |
| 84 | MP0002136_abnormal_kidney_physiology | 0.55497655 |
| 85 | MP0008004_abnormal_stomach_pH | 0.53493534 |
| 86 | MP0005645_abnormal_hypothalamus_physiol | 0.52186821 |
| 87 | MP0002928_abnormal_bile_duct | 0.51521110 |
| 88 | MP0005381_digestive/alimentary_phenotyp | 0.51030149 |
| 89 | MP0008874_decreased_physiological_sensi | 0.50247565 |
| 90 | MP0002693_abnormal_pancreas_physiology | 0.50073740 |
| 91 | MP0005390_skeleton_phenotype | 0.46672099 |
| 92 | MP0003795_abnormal_bone_structure | 0.46229128 |
| 93 | MP0002277_abnormal_respiratory_mucosa | 0.45408141 |
| 94 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.44965511 |
| 95 | MP0006036_abnormal_mitochondrial_physio | 0.44442833 |
| 96 | MP0005164_abnormal_response_to | 0.43245996 |
| 97 | MP0000609_abnormal_liver_physiology | 0.41220460 |
| 98 | MP0009642_abnormal_blood_homeostasis | 0.40916348 |
| 99 | MP0000371_diluted_coat_color | 0.40508557 |
| 100 | MP0000313_abnormal_cell_death | 0.36715565 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Agammaglobulinemia (HP:0004432) | 6.22226297 |
| 2 | Meningitis (HP:0001287) | 5.58646687 |
| 3 | Eczematoid dermatitis (HP:0000976) | 5.34110046 |
| 4 | Recurrent bacterial skin infections (HP:0005406) | 5.23293944 |
| 5 | Chronic obstructive pulmonary disease (HP:0006510) | 5.00328310 |
| 6 | Obstructive lung disease (HP:0006536) | 5.00328310 |
| 7 | Recurrent abscess formation (HP:0002722) | 5.00213091 |
| 8 | Vasculitis (HP:0002633) | 4.78555238 |
| 9 | Mediastinal lymphadenopathy (HP:0100721) | 4.77537027 |
| 10 | Gastrointestinal stroma tumor (HP:0100723) | 4.65211799 |
| 11 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.47318891 |
| 12 | Recurrent cutaneous fungal infections (HP:0011370) | 4.47318891 |
| 13 | Cellulitis (HP:0100658) | 4.40000787 |
| 14 | Recurrent fungal infections (HP:0002841) | 4.32295351 |
| 15 | Abnormality of macrophages (HP:0004311) | 4.22844102 |
| 16 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.20428169 |
| 17 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.09658811 |
| 18 | Recurrent bronchitis (HP:0002837) | 4.09419393 |
| 19 | Panhypogammaglobulinemia (HP:0003139) | 4.08418487 |
| 20 | Gastrointestinal infarctions (HP:0005244) | 4.06126184 |
| 21 | Colitis (HP:0002583) | 4.03092262 |
| 22 | Recurrent skin infections (HP:0001581) | 4.01250810 |
| 23 | Recurrent viral infections (HP:0004429) | 3.98504535 |
| 24 | Recurrent sinusitis (HP:0011108) | 3.98326150 |
| 25 | Hemoptysis (HP:0002105) | 3.63379317 |
| 26 | Chest pain (HP:0100749) | 3.62745890 |
| 27 | Pulmonary infiltrates (HP:0002113) | 3.62022703 |
| 28 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.60869148 |
| 29 | Inflammation of the large intestine (HP:0002037) | 3.57396908 |
| 30 | Myositis (HP:0100614) | 3.56568361 |
| 31 | Urticaria (HP:0001025) | 3.56457816 |
| 32 | Abnormality of the prostate (HP:0008775) | 3.53491748 |
| 33 | Lymphopenia (HP:0001888) | 3.52488862 |
| 34 | Gastrointestinal inflammation (HP:0004386) | 3.47765858 |
| 35 | Osteomyelitis (HP:0002754) | 3.47212293 |
| 36 | Restrictive lung disease (HP:0002091) | 3.39132763 |
| 37 | Papilloma (HP:0012740) | 3.34141154 |
| 38 | Verrucae (HP:0200043) | 3.34141154 |
| 39 | Encephalitis (HP:0002383) | 3.26561517 |
| 40 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.26116506 |
| 41 | Skin rash (HP:0000988) | 3.22749382 |
| 42 | Abnormality of the pleura (HP:0002103) | 3.22644273 |
| 43 | Emphysema (HP:0002097) | 3.22163540 |
| 44 | Recurrent pneumonia (HP:0006532) | 3.22045214 |
| 45 | Optic neuritis (HP:0100653) | 3.20296486 |
| 46 | Retrobulbar optic neuritis (HP:0100654) | 3.20296486 |
| 47 | Orchitis (HP:0100796) | 3.19629494 |
| 48 | Increased IgE level (HP:0003212) | 3.03291604 |
| 49 | IgM deficiency (HP:0002850) | 2.98458098 |
| 50 | Recurrent lower respiratory tract infections (HP:0002783) | 2.97873426 |
| 51 | Stomatitis (HP:0010280) | 2.83467106 |
| 52 | Chronic otitis media (HP:0000389) | 2.77819561 |
| 53 | Sepsis (HP:0100806) | 2.77002243 |
| 54 | Epistaxis (HP:0000421) | 2.70211106 |
| 55 | Gingivitis (HP:0000230) | 2.64753850 |
| 56 | Chronic sinusitis (HP:0011109) | 2.63716450 |
| 57 | Abnormality of T cell physiology (HP:0011840) | 2.57804995 |
| 58 | Increased IgM level (HP:0003496) | 2.55704029 |
| 59 | Skin ulcer (HP:0200042) | 2.55586834 |
| 60 | Abnormality of T cells (HP:0002843) | 2.49300864 |
| 61 | Prolonged bleeding time (HP:0003010) | 2.48417847 |
| 62 | Gingival bleeding (HP:0000225) | 2.47860457 |
| 63 | Pulmonary embolism (HP:0002204) | 2.46903077 |
| 64 | Gangrene (HP:0100758) | 2.45996089 |
| 65 | Petechiae (HP:0000967) | 2.43093611 |
| 66 | Spontaneous hematomas (HP:0007420) | 2.42930339 |
| 67 | Arterial thrombosis (HP:0004420) | 2.41230160 |
| 68 | Glomerulopathy (HP:0100820) | 2.40641973 |
| 69 | Amyloidosis (HP:0011034) | 2.39454853 |
| 70 | IgG deficiency (HP:0004315) | 2.38226517 |
| 71 | Abnormality of the peritoneum (HP:0002585) | 2.37932200 |
| 72 | Keratoconjunctivitis sicca (HP:0001097) | 2.37792177 |
| 73 | Acrocyanosis (HP:0001063) | 2.37723538 |
| 74 | Fatigue (HP:0012378) | 2.34859075 |
| 75 | Pustule (HP:0200039) | 2.33696696 |
| 76 | Pulmonary fibrosis (HP:0002206) | 2.32206353 |
| 77 | Viral hepatitis (HP:0006562) | 2.30647815 |
| 78 | Bronchitis (HP:0012387) | 2.30198121 |
| 79 | Keratoconjunctivitis (HP:0001096) | 2.28564273 |
| 80 | Chronic diarrhea (HP:0002028) | 2.24524051 |
| 81 | Abnormality of B cell number (HP:0010975) | 2.24471485 |
| 82 | Hypertensive crisis (HP:0100735) | 2.23142119 |
| 83 | Lymphoma (HP:0002665) | 2.23046706 |
| 84 | Amaurosis fugax (HP:0100576) | 2.21136604 |
| 85 | Abnormality of male internal genitalia (HP:0000022) | 2.18677340 |
| 86 | Abnormality of T cell number (HP:0011839) | 2.15595822 |
| 87 | Leukocytosis (HP:0001974) | 2.15402927 |
| 88 | Granulocytopenia (HP:0001913) | 2.14781559 |
| 89 | Arthralgia (HP:0002829) | 2.14670306 |
| 90 | T lymphocytopenia (HP:0005403) | 2.13890051 |
| 91 | Anorexia (HP:0002039) | 2.11048097 |
| 92 | Recurrent otitis media (HP:0000403) | 2.09515045 |
| 93 | B lymphocytopenia (HP:0010976) | 2.09512533 |
| 94 | Xerostomia (HP:0000217) | 2.08787063 |
| 95 | Hypoplasia of the thymus (HP:0000778) | 2.07818637 |
| 96 | Systemic lupus erythematosus (HP:0002725) | 2.05284415 |
| 97 | Purpura (HP:0000979) | 2.04855218 |
| 98 | Hypergammaglobulinemia (HP:0010702) | 2.03972648 |
| 99 | Polyneuropathy (HP:0001271) | 2.01925351 |
| 100 | Ureteral stenosis (HP:0000071) | 1.97678293 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 5.21311230 |
| 2 | RIPK4 | 4.99278746 |
| 3 | BLK | 3.98453336 |
| 4 | TYK2 | 3.19210412 |
| 5 | ERN1 | 3.00534488 |
| 6 | BMPR2 | 2.73296747 |
| 7 | CSF1R | 2.66729659 |
| 8 | IRAK4 | 2.64446068 |
| 9 | JAK3 | 2.60437980 |
| 10 | SYK | 2.43790474 |
| 11 | MAP3K13 | 2.26734842 |
| 12 | BTK | 2.26293474 |
| 13 | MAP3K14 | 2.21527133 |
| 14 | FES | 2.11458308 |
| 15 | KIT | 2.05113119 |
| 16 | PRPF4B | 2.02866913 |
| 17 | IKBKE | 1.97364203 |
| 18 | CSK | 1.85343786 |
| 19 | CDK19 | 1.83229180 |
| 20 | LYN | 1.76017246 |
| 21 | TNK2 | 1.62408588 |
| 22 | TBK1 | 1.60430870 |
| 23 | ITK | 1.56272768 |
| 24 | JAK1 | 1.53238146 |
| 25 | GRK6 | 1.50016751 |
| 26 | MAP2K3 | 1.49646080 |
| 27 | IKBKB | 1.48433655 |
| 28 | MAP3K10 | 1.47489245 |
| 29 | ZAP70 | 1.47092819 |
| 30 | HCK | 1.45313619 |
| 31 | SIK3 | 1.41031321 |
| 32 | TEC | 1.34460192 |
| 33 | TESK2 | 1.24176538 |
| 34 | FGR | 1.22784780 |
| 35 | LCK | 1.22187695 |
| 36 | TXK | 1.19920180 |
| 37 | SIK2 | 1.11538930 |
| 38 | PIK3CG | 1.07823040 |
| 39 | JAK2 | 1.03152428 |
| 40 | MARK3 | 0.96341145 |
| 41 | PDK1 | 0.94625444 |
| 42 | MATK | 0.90011035 |
| 43 | MAPK12 | 0.87408588 |
| 44 | STK10 | 0.82844714 |
| 45 | PRKCQ | 0.76739111 |
| 46 | MAPK7 | 0.75795147 |
| 47 | TAOK3 | 0.71999714 |
| 48 | MAP3K11 | 0.71407451 |
| 49 | SMG1 | 0.71043801 |
| 50 | MAP3K3 | 0.69144108 |
| 51 | MAPK11 | 0.68270077 |
| 52 | KDR | 0.67581432 |
| 53 | PDPK1 | 0.65530838 |
| 54 | FGFR4 | 0.64628727 |
| 55 | MAP3K1 | 0.64079881 |
| 56 | CDC42BPA | 0.63942312 |
| 57 | FYN | 0.60164534 |
| 58 | TLK1 | 0.57459883 |
| 59 | LRRK2 | 0.57385300 |
| 60 | PASK | 0.57167677 |
| 61 | CDK4 | 0.56500467 |
| 62 | TAOK1 | 0.56152111 |
| 63 | TRIB3 | 0.52235606 |
| 64 | RPS6KA4 | 0.50357989 |
| 65 | TAOK2 | 0.50274372 |
| 66 | HIPK2 | 0.49634973 |
| 67 | PIM1 | 0.48417528 |
| 68 | YES1 | 0.48246495 |
| 69 | IRAK1 | 0.44660873 |
| 70 | SCYL2 | 0.43922482 |
| 71 | MAP3K8 | 0.43711048 |
| 72 | ABL1 | 0.43683748 |
| 73 | FGFR3 | 0.43666806 |
| 74 | MOS | 0.43578270 |
| 75 | IRAK2 | 0.42745989 |
| 76 | MARK2 | 0.42714036 |
| 77 | NEK9 | 0.41332067 |
| 78 | KSR2 | 0.41149972 |
| 79 | CHUK | 0.40903092 |
| 80 | MAP2K2 | 0.40879482 |
| 81 | MAPKAPK2 | 0.39193802 |
| 82 | MAP3K12 | 0.38453382 |
| 83 | GRK7 | 0.36224470 |
| 84 | SIK1 | 0.34661338 |
| 85 | CDK12 | 0.34214598 |
| 86 | EPHB1 | 0.34151625 |
| 87 | NME2 | 0.33895567 |
| 88 | MAPK4 | 0.33579324 |
| 89 | PRKCD | 0.33428161 |
| 90 | MAP3K7 | 0.30707114 |
| 91 | RPS6KL1 | 0.30573429 |
| 92 | RPS6KC1 | 0.30573429 |
| 93 | EGFR | 0.29876603 |
| 94 | OXSR1 | 0.28569176 |
| 95 | CCNB1 | 0.28039733 |
| 96 | ARAF | 0.26587377 |
| 97 | TGFBR2 | 0.25307376 |
| 98 | MST4 | 0.24284718 |
| 99 | RPS6KA6 | 0.23279371 |
| 100 | DYRK1B | 0.22474911 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 5.09140855 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 4.88026973 |
| 3 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 4.74735298 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 4.55972935 |
| 5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 4.16483188 |
| 6 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 3.88627326 |
| 7 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.37510204 |
| 8 | Leishmaniasis_Homo sapiens_hsa05140 | 3.26503250 |
| 9 | Viral myocarditis_Homo sapiens_hsa05416 | 3.02010213 |
| 10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.94861715 |
| 11 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.90867651 |
| 12 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.50005945 |
| 13 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.33590640 |
| 14 | Tuberculosis_Homo sapiens_hsa05152 | 1.93787624 |
| 15 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.86898781 |
| 16 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.80914391 |
| 17 | Influenza A_Homo sapiens_hsa05164 | 1.79459171 |
| 18 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.77973623 |
| 19 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.71554678 |
| 20 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.66990813 |
| 21 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.50104112 |
| 22 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.39822202 |
| 23 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.33451569 |
| 24 | Phagosome_Homo sapiens_hsa04145 | 1.29463953 |
| 25 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.25215972 |
| 26 | Measles_Homo sapiens_hsa05162 | 1.22480073 |
| 27 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.17306095 |
| 28 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.06862936 |
| 29 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.05205977 |
| 30 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.98842364 |
| 31 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.98034759 |
| 32 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.94527848 |
| 33 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.88343013 |
| 34 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.87160567 |
| 35 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.86841094 |
| 36 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.75605542 |
| 37 | Pertussis_Homo sapiens_hsa05133 | 0.75579954 |
| 38 | HTLV-I infection_Homo sapiens_hsa05166 | 0.67555017 |
| 39 | Legionellosis_Homo sapiens_hsa05134 | 0.67523087 |
| 40 | Hepatitis B_Homo sapiens_hsa05161 | 0.65280503 |
| 41 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.65230913 |
| 42 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.63953407 |
| 43 | Malaria_Homo sapiens_hsa05144 | 0.59836216 |
| 44 | Hepatitis C_Homo sapiens_hsa05160 | 0.59714448 |
| 45 | Platelet activation_Homo sapiens_hsa04611 | 0.59506442 |
| 46 | Other glycan degradation_Homo sapiens_hsa00511 | 0.57970995 |
| 47 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.54809784 |
| 48 | Shigellosis_Homo sapiens_hsa05131 | 0.52536654 |
| 49 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.48841800 |
| 50 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.46537658 |
| 51 | Salmonella infection_Homo sapiens_hsa05132 | 0.45950729 |
| 52 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.43939836 |
| 53 | Apoptosis_Homo sapiens_hsa04210 | 0.43001033 |
| 54 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.40477873 |
| 55 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.37053228 |
| 56 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.35913544 |
| 57 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.34555282 |
| 58 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.32837859 |
| 59 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.30005114 |
| 60 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.28802648 |
| 61 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.26177575 |
| 62 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.25385625 |
| 63 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.22125625 |
| 64 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.22022581 |
| 65 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.21449811 |
| 66 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.21140907 |
| 67 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.21070275 |
| 68 | Lysosome_Homo sapiens_hsa04142 | 0.17891693 |
| 69 | Endocytosis_Homo sapiens_hsa04144 | 0.17826509 |
| 70 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.16484307 |
| 71 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.15532478 |
| 72 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.14074524 |
| 73 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.12046116 |
| 74 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.11594305 |
| 75 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.11165076 |
| 76 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.10745293 |
| 77 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.08191605 |
| 78 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.06708356 |
| 79 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.05641848 |
| 80 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.05616961 |
| 81 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.05488369 |
| 82 | Ribosome_Homo sapiens_hsa03010 | 0.02960261 |
| 83 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.02806021 |
| 84 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.02762642 |
| 85 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.02111709 |
| 86 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.00392430 |
| 87 | Prostate cancer_Homo sapiens_hsa05215 | -0.0994381 |
| 88 | Cholinergic synapse_Homo sapiens_hsa04725 | -0.0986308 |
| 89 | Amoebiasis_Homo sapiens_hsa05146 | -0.0983952 |
| 90 | mTOR signaling pathway_Homo sapiens_hsa04150 | -0.0901214 |
| 91 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | -0.0862374 |
| 92 | Type II diabetes mellitus_Homo sapiens_hsa04930 | -0.0787584 |
| 93 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | -0.0655237 |
| 94 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.0604425 |
| 95 | Colorectal cancer_Homo sapiens_hsa05210 | -0.0425871 |
| 96 | Insulin resistance_Homo sapiens_hsa04931 | -0.0417829 |
| 97 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | -0.0343708 |
| 98 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | -0.0233489 |
| 99 | Alcoholism_Homo sapiens_hsa05034 | -0.0091543 |
| 100 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | -0.0086645 |

