Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of translational termination (GO:0006449) | 5.57998702 |
2 | regulation of translational fidelity (GO:0006450) | 5.17629336 |
3 | folic acid-containing compound biosynthetic process (GO:0009396) | 5.14824288 |
4 | establishment of integrated proviral latency (GO:0075713) | 5.10750681 |
5 | * tRNA aminoacylation for protein translation (GO:0006418) | 4.96464291 |
6 | formation of translation preinitiation complex (GO:0001731) | 4.80447467 |
7 | * amino acid activation (GO:0043038) | 4.78260349 |
8 | * tRNA aminoacylation (GO:0043039) | 4.78260349 |
9 | COPI coating of Golgi vesicle (GO:0048205) | 4.77537481 |
10 | Golgi transport vesicle coating (GO:0048200) | 4.77537481 |
11 | nucleobase biosynthetic process (GO:0046112) | 4.62896403 |
12 | IMP biosynthetic process (GO:0006188) | 4.57645672 |
13 | purine nucleobase biosynthetic process (GO:0009113) | 4.39156909 |
14 | cullin deneddylation (GO:0010388) | 4.38781349 |
15 | peptidyl-arginine omega-N-methylation (GO:0035247) | 4.37929322 |
16 | protein localization to kinetochore (GO:0034501) | 4.19159047 |
17 | nuclear pore organization (GO:0006999) | 4.18838560 |
18 | ribosome assembly (GO:0042255) | 4.18202674 |
19 | protein deneddylation (GO:0000338) | 4.06069982 |
20 | mitotic sister chromatid segregation (GO:0000070) | 4.03656592 |
21 | IMP metabolic process (GO:0046040) | 3.97663896 |
22 | peptidyl-arginine methylation (GO:0018216) | 3.95090518 |
23 | peptidyl-arginine N-methylation (GO:0035246) | 3.95090518 |
24 | oxaloacetate metabolic process (GO:0006107) | 3.94211715 |
25 | histone arginine methylation (GO:0034969) | 3.86403288 |
26 | establishment of viral latency (GO:0019043) | 3.85919844 |
27 | NADH metabolic process (GO:0006734) | 3.81438754 |
28 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.80963087 |
29 | nuclear pore complex assembly (GO:0051292) | 3.80256888 |
30 | ribosome biogenesis (GO:0042254) | 3.80065692 |
31 | mitotic sister chromatid cohesion (GO:0007064) | 3.74802664 |
32 | regulation of translational elongation (GO:0006448) | 3.70722832 |
33 | sister chromatid segregation (GO:0000819) | 3.70612416 |
34 | mitotic nuclear envelope disassembly (GO:0007077) | 3.67881047 |
35 | cellular protein complex localization (GO:0034629) | 3.66665184 |
36 | protein complex localization (GO:0031503) | 3.63775477 |
37 | nuclear envelope disassembly (GO:0051081) | 3.58380369 |
38 | membrane disassembly (GO:0030397) | 3.58380369 |
39 | de novo protein folding (GO:0006458) | 3.58325291 |
40 | DNA unwinding involved in DNA replication (GO:0006268) | 3.54404263 |
41 | chaperone-mediated protein complex assembly (GO:0051131) | 3.53660364 |
42 | DNA strand elongation (GO:0022616) | 3.48241501 |
43 | non-recombinational repair (GO:0000726) | 3.48024058 |
44 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.48024058 |
45 | de novo posttranslational protein folding (GO:0051084) | 3.43692365 |
46 | mitotic metaphase plate congression (GO:0007080) | 3.38742185 |
47 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.36047386 |
48 | CENP-A containing nucleosome assembly (GO:0034080) | 3.35508906 |
49 | chromatin remodeling at centromere (GO:0031055) | 3.29156219 |
50 | mitotic spindle checkpoint (GO:0071174) | 3.24711372 |
51 | RNA-dependent DNA replication (GO:0006278) | 3.23135389 |
52 | DNA replication initiation (GO:0006270) | 3.22904722 |
53 | spindle checkpoint (GO:0031577) | 3.21690320 |
54 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.20535249 |
55 | negative regulation of sister chromatid segregation (GO:0033046) | 3.18810983 |
56 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.18810983 |
57 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.18810983 |
58 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.18810983 |
59 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.18810983 |
60 | negative regulation of chromosome segregation (GO:0051985) | 3.17496298 |
61 | mitotic chromosome condensation (GO:0007076) | 3.15915061 |
62 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.14825307 |
63 | tetrahydrofolate metabolic process (GO:0046653) | 3.14257922 |
64 | regulation of centriole replication (GO:0046599) | 3.14150572 |
65 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 3.13851248 |
66 | ATP hydrolysis coupled proton transport (GO:0015991) | 3.13851248 |
67 | DNA topological change (GO:0006265) | 3.12995560 |
68 | serine family amino acid biosynthetic process (GO:0009070) | 3.12326258 |
69 | DNA ligation (GO:0006266) | 3.11630471 |
70 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.11230206 |
71 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.10069125 |
72 | regulation of chromosome segregation (GO:0051983) | 3.09968710 |
73 | transferrin transport (GO:0033572) | 3.09801988 |
74 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.06115916 |
75 | pore complex assembly (GO:0046931) | 3.04750795 |
76 | protein-cofactor linkage (GO:0018065) | 3.03153392 |
77 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.00793539 |
78 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.00793539 |
79 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.98341312 |
80 | mitotic spindle assembly checkpoint (GO:0007094) | 2.98097624 |
81 | postreplication repair (GO:0006301) | 2.97437079 |
82 | tricarboxylic acid cycle (GO:0006099) | 2.96787161 |
83 | spindle assembly checkpoint (GO:0071173) | 2.95323823 |
84 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.94610153 |
85 | cell cycle G1/S phase transition (GO:0044843) | 2.94610153 |
86 | telomere maintenance via telomerase (GO:0007004) | 2.94166639 |
87 | ferric iron transport (GO:0015682) | 2.94058804 |
88 | trivalent inorganic cation transport (GO:0072512) | 2.94058804 |
89 | regulation of translational initiation (GO:0006446) | 2.93530518 |
90 | proteasome assembly (GO:0043248) | 2.92446705 |
91 | cellular response to glucose starvation (GO:0042149) | 2.91838275 |
92 | negative regulation of ligase activity (GO:0051352) | 2.89953686 |
93 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.89953686 |
94 | glutamine metabolic process (GO:0006541) | 2.88323651 |
95 | regulation of spindle organization (GO:0090224) | 2.88162145 |
96 | regulation of sister chromatid segregation (GO:0033045) | 2.88009750 |
97 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.88009750 |
98 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.88009750 |
99 | histone exchange (GO:0043486) | 2.87391667 |
100 | regulation of translation in response to stress (GO:0043555) | 2.87227625 |
101 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.86770336 |
102 | DNA replication-independent nucleosome organization (GO:0034724) | 2.86770336 |
103 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.86037604 |
104 | regulation of mitotic spindle organization (GO:0060236) | 2.85760199 |
105 | DNA double-strand break processing (GO:0000729) | 2.84483858 |
106 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.81989597 |
107 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.81888096 |
108 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.81510689 |
109 | regulation of centrosome cycle (GO:0046605) | 2.80763027 |
110 | establishment of chromosome localization (GO:0051303) | 2.79468692 |
111 | regulation of oxidative stress-induced neuron death (GO:1903203) | 2.78926796 |
112 | ER overload response (GO:0006983) | 2.78766207 |
113 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.78240151 |
114 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.78240151 |
115 | L-serine metabolic process (GO:0006563) | 2.77517319 |
116 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.77067171 |
117 | COPII vesicle coating (GO:0048208) | 2.75933548 |
118 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.74860591 |
119 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.74860591 |
120 | mitochondrial DNA metabolic process (GO:0032042) | 2.74011642 |
121 | protein localization to chromosome, centromeric region (GO:0071459) | 2.73827777 |
122 | mitotic recombination (GO:0006312) | 2.72579478 |
123 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.71154772 |
124 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.71154772 |
125 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.71154772 |
126 | aspartate family amino acid biosynthetic process (GO:0009067) | 2.70643485 |
127 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.70013668 |
128 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.69357018 |
129 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.69357018 |
130 | metaphase plate congression (GO:0051310) | 2.68917128 |
131 | positive regulation of chromosome segregation (GO:0051984) | 2.68079030 |
132 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.67606162 |
133 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.66771373 |
134 | positive regulation of ligase activity (GO:0051351) | 2.65779999 |
135 | response to X-ray (GO:0010165) | 2.65330255 |
136 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.65255143 |
137 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.63850648 |
138 | nucleotide-sugar biosynthetic process (GO:0009226) | 2.63480535 |
139 | positive regulation of nuclease activity (GO:0032075) | 2.61346675 |
140 | telomere maintenance via recombination (GO:0000722) | 2.61045035 |
141 | DNA duplex unwinding (GO:0032508) | 2.60809933 |
142 | DNA geometric change (GO:0032392) | 2.60726034 |
143 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.60609838 |
144 | nuclear envelope organization (GO:0006998) | 2.60248886 |
145 | chaperone-mediated protein folding (GO:0061077) | 2.60170867 |
146 | galactose catabolic process (GO:0019388) | 2.59741953 |
147 | heterochromatin organization (GO:0070828) | 2.57967290 |
148 | regulation of helicase activity (GO:0051095) | 2.57930995 |
149 | DNA replication checkpoint (GO:0000076) | 2.57766366 |
150 | regulation of sister chromatid cohesion (GO:0007063) | 2.57763888 |
151 | ribosomal large subunit biogenesis (GO:0042273) | 2.57465546 |
152 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.56562605 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.01430115 |
2 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.72020061 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 4.36190558 |
4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.55635609 |
5 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.34232070 |
6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.31370272 |
7 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.19106468 |
8 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.06839094 |
9 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.06705340 |
10 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 3.06587824 |
11 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.03874647 |
12 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.02382866 |
13 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.95384172 |
14 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.86381951 |
15 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.79751342 |
16 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.71162196 |
17 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.69900969 |
18 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.63507153 |
19 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.60429028 |
20 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.59549020 |
21 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 2.38846784 |
22 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.31077521 |
23 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.30588799 |
24 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.26473065 |
25 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 2.26343120 |
26 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.22315104 |
27 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.22179372 |
28 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.21911651 |
29 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.18570001 |
30 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.17353388 |
31 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 2.13845121 |
32 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 2.13391293 |
33 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.10505043 |
34 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.08218777 |
35 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.99578004 |
36 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.99041370 |
37 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.93998093 |
38 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.93446209 |
39 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.93062386 |
40 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.86073438 |
41 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.86016426 |
42 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.80258127 |
43 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.79660142 |
44 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.79311249 |
45 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.79157142 |
46 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.75466746 |
47 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.70323099 |
48 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.66699285 |
49 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.66504830 |
50 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.63234297 |
51 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.61424541 |
52 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.52861987 |
53 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.51838328 |
54 | * ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.51747104 |
55 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.47384367 |
56 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.43062135 |
57 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.38523803 |
58 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.36863086 |
59 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.35831170 |
60 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.32879425 |
61 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.32755336 |
62 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.30697726 |
63 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.30072672 |
64 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.28494274 |
65 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.26918370 |
66 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.26672339 |
67 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.23966818 |
68 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.23808888 |
69 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.21974715 |
70 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.19150658 |
71 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.18450829 |
72 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.15867917 |
73 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.13729568 |
74 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.11717756 |
75 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.08337882 |
76 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.08196299 |
77 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.07963535 |
78 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.07910628 |
79 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.07360623 |
80 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.05941739 |
81 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.05846564 |
82 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.05657008 |
83 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.05378812 |
84 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.04928542 |
85 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.04850957 |
86 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.03302101 |
87 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.03133370 |
88 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 1.02764508 |
89 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.02523461 |
90 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.01128068 |
91 | * ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.99217556 |
92 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.98345914 |
93 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.97527869 |
94 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.97282779 |
95 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.97054496 |
96 | * ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.96710672 |
97 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.96697281 |
98 | * SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.96606964 |
99 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.96204620 |
100 | * MYC_22102868_ChIP-Seq_BL_Human | 0.95538708 |
101 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.95041431 |
102 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.94356828 |
103 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.93655293 |
104 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.93639617 |
105 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.93564618 |
106 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.92911971 |
107 | * CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.91268018 |
108 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.90366969 |
109 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.90309619 |
110 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.89364349 |
111 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.89140046 |
112 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.89058975 |
113 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.87238815 |
114 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.86917556 |
115 | * CIITA_25753668_ChIP-Seq_RAJI_Human | 0.86752797 |
116 | * GATA4_21415370_ChIP-Seq_HL-1_Mouse | 0.84848309 |
117 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.84365362 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003941_abnormal_skin_development | 4.11498991 |
2 | MP0004957_abnormal_blastocyst_morpholog | 3.90036051 |
3 | MP0003693_abnormal_embryo_hatching | 3.84842192 |
4 | MP0003123_paternal_imprinting | 3.50211667 |
5 | MP0010352_gastrointestinal_tract_polyps | 3.33597466 |
6 | MP0003111_abnormal_nucleus_morphology | 2.72683349 |
7 | MP0010094_abnormal_chromosome_stability | 2.63778659 |
8 | MP0003705_abnormal_hypodermis_morpholog | 2.59633153 |
9 | MP0003077_abnormal_cell_cycle | 2.58645148 |
10 | MP0008438_abnormal_cutaneous_collagen | 2.51432802 |
11 | MP0004233_abnormal_muscle_weight | 2.50339895 |
12 | MP0010307_abnormal_tumor_latency | 2.37946996 |
13 | MP0008932_abnormal_embryonic_tissue | 2.30076323 |
14 | MP0002735_abnormal_chemical_nociception | 2.07094893 |
15 | MP0002877_abnormal_melanocyte_morpholog | 1.98111891 |
16 | MP0001730_embryonic_growth_arrest | 1.95579594 |
17 | MP0003806_abnormal_nucleotide_metabolis | 1.91815817 |
18 | MP0000350_abnormal_cell_proliferation | 1.91795542 |
19 | MP0009697_abnormal_copulation | 1.90271414 |
20 | MP0009780_abnormal_chondrocyte_physiolo | 1.89662111 |
21 | MP0004272_abnormal_basement_membrane | 1.80484358 |
22 | MP0003566_abnormal_cell_adhesion | 1.77864154 |
23 | MP0002736_abnormal_nociception_after | 1.71795542 |
24 | MP0008007_abnormal_cellular_replicative | 1.70947525 |
25 | MP0009046_muscle_twitch | 1.69853694 |
26 | MP0009672_abnormal_birth_weight | 1.63664497 |
27 | MP0005623_abnormal_meninges_morphology | 1.62803118 |
28 | MP0004859_abnormal_synaptic_plasticity | 1.62741021 |
29 | MP0005408_hypopigmentation | 1.60784617 |
30 | MP0001542_abnormal_bone_strength | 1.60671458 |
31 | MP0008057_abnormal_DNA_replication | 1.57324123 |
32 | MP0003787_abnormal_imprinting | 1.56647343 |
33 | MP0005076_abnormal_cell_differentiation | 1.56133280 |
34 | MP0003121_genomic_imprinting | 1.55243722 |
35 | MP0000358_abnormal_cell_content/ | 1.53941384 |
36 | MP0001697_abnormal_embryo_size | 1.51734198 |
37 | MP0002080_prenatal_lethality | 1.46482299 |
38 | MP0001968_abnormal_touch/_nociception | 1.44816097 |
39 | MP0004197_abnormal_fetal_growth/weight/ | 1.42233698 |
40 | MP0001299_abnormal_eye_distance/ | 1.41845576 |
41 | MP0008058_abnormal_DNA_repair | 1.40502339 |
42 | MP0005023_abnormal_wound_healing | 1.40174448 |
43 | MP0004270_analgesia | 1.36702507 |
44 | MP0003283_abnormal_digestive_organ | 1.36189960 |
45 | MP0005503_abnormal_tendon_morphology | 1.36161956 |
46 | MP0003122_maternal_imprinting | 1.35265017 |
47 | MP0002734_abnormal_mechanical_nocicepti | 1.34807832 |
48 | MP0001672_abnormal_embryogenesis/_devel | 1.33873559 |
49 | MP0005380_embryogenesis_phenotype | 1.33873559 |
50 | MP0000537_abnormal_urethra_morphology | 1.31866689 |
51 | MP0000013_abnormal_adipose_tissue | 1.30883405 |
52 | MP0006054_spinal_hemorrhage | 1.30843482 |
53 | MP0003937_abnormal_limbs/digits/tail_de | 1.28874393 |
54 | MP0003567_abnormal_fetal_cardiomyocyte | 1.27412638 |
55 | MP0003984_embryonic_growth_retardation | 1.27339107 |
56 | MP0002084_abnormal_developmental_patter | 1.24425689 |
57 | MP0002088_abnormal_embryonic_growth/wei | 1.24386395 |
58 | MP0000579_abnormal_nail_morphology | 1.23574066 |
59 | MP0005275_abnormal_skin_tensile | 1.22296427 |
60 | MP0003635_abnormal_synaptic_transmissio | 1.19545437 |
61 | MP0002796_impaired_skin_barrier | 1.18357054 |
62 | MP0001293_anophthalmia | 1.17029156 |
63 | MP0005384_cellular_phenotype | 1.16431075 |
64 | MP0008877_abnormal_DNA_methylation | 1.16361556 |
65 | MP0001348_abnormal_lacrimal_gland | 1.15554559 |
66 | MP0001661_extended_life_span | 1.15379847 |
67 | MP0002090_abnormal_vision | 1.12939360 |
68 | MP0002064_seizures | 1.12891851 |
69 | MP0005621_abnormal_cell_physiology | 1.12851348 |
70 | MP0004811_abnormal_neuron_physiology | 1.10814161 |
71 | MP0002697_abnormal_eye_size | 1.10128350 |
72 | MP0005501_abnormal_skin_physiology | 1.09989669 |
73 | MP0002086_abnormal_extraembryonic_tissu | 1.09727611 |
74 | MP0006035_abnormal_mitochondrial_morpho | 1.08806761 |
75 | MP0003718_maternal_effect | 1.08796993 |
76 | MP0003186_abnormal_redox_activity | 1.06759833 |
77 | MP0001915_intracranial_hemorrhage | 1.06453069 |
78 | MP0006036_abnormal_mitochondrial_physio | 1.06197240 |
79 | MP0002060_abnormal_skin_morphology | 1.05173532 |
80 | MP0002085_abnormal_embryonic_tissue | 1.03206867 |
81 | MP0003656_abnormal_erythrocyte_physiolo | 1.02836453 |
82 | MP0008004_abnormal_stomach_pH | 1.02533659 |
83 | MP0003950_abnormal_plasma_membrane | 1.00390389 |
84 | MP0002269_muscular_atrophy | 0.98465971 |
85 | MP0003890_abnormal_embryonic-extraembry | 0.97844465 |
86 | MP0003786_premature_aging | 0.97281954 |
87 | MP0002063_abnormal_learning/memory/cond | 0.96852623 |
88 | MP0002733_abnormal_thermal_nociception | 0.96732040 |
89 | MP0009745_abnormal_behavioral_response | 0.95889747 |
90 | MP0002896_abnormal_bone_mineralization | 0.95771214 |
91 | MP0004147_increased_porphyrin_level | 0.94129790 |
92 | MP0000467_abnormal_esophagus_morphology | 0.94031318 |
93 | MP0003385_abnormal_body_wall | 0.93533246 |
94 | MP0004185_abnormal_adipocyte_glucose | 0.91275132 |
95 | MP0002254_reproductive_system_inflammat | 0.90732950 |
96 | MP0000747_muscle_weakness | 0.89790735 |
97 | MP0001849_ear_inflammation | 0.89352591 |
98 | MP0000647_abnormal_sebaceous_gland | 0.88390287 |
99 | MP0002751_abnormal_autonomic_nervous | 0.88271762 |
100 | MP0009053_abnormal_anal_canal | 0.87747645 |
101 | MP0002396_abnormal_hematopoietic_system | 0.85829984 |
102 | MP0000750_abnormal_muscle_regeneration | 0.85499885 |
103 | MP0000762_abnormal_tongue_morphology | 0.84990448 |
104 | MP0004264_abnormal_extraembryonic_tissu | 0.84304768 |
105 | MP0002111_abnormal_tail_morphology | 0.83630028 |
106 | MP0001188_hyperpigmentation | 0.83110192 |
107 | MP0001177_atelectasis | 0.83072767 |
108 | MP0005266_abnormal_metabolism | 0.83060458 |
109 | MP0004858_abnormal_nervous_system | 0.82527595 |
110 | MP0003879_abnormal_hair_cell | 0.81630959 |
111 | MP0001970_abnormal_pain_threshold | 0.81030537 |
112 | MP0000749_muscle_degeneration | 0.80841069 |
113 | MP0005187_abnormal_penis_morphology | 0.79595889 |
114 | MP0002233_abnormal_nose_morphology | 0.79528539 |
115 | MP0000751_myopathy | 0.78919356 |
116 | MP0003119_abnormal_digestive_system | 0.78716104 |
117 | MP0000490_abnormal_crypts_of | 0.78250127 |
118 | MP0004084_abnormal_cardiac_muscle | 0.78235155 |
119 | MP0000858_altered_metastatic_potential | 0.77710426 |
120 | MP0000377_abnormal_hair_follicle | 0.77231625 |
121 | MP0000313_abnormal_cell_death | 0.74914455 |
122 | MP0005257_abnormal_intraocular_pressure | 0.74263464 |
123 | MP0002102_abnormal_ear_morphology | 0.74105913 |
124 | MP0002009_preneoplasia | 0.73869326 |
125 | MP0001286_abnormal_eye_development | 0.73610156 |
126 | MP0004215_abnormal_myocardial_fiber | 0.72614938 |
127 | MP0001243_abnormal_dermal_layer | 0.72542539 |
128 | MP0010234_abnormal_vibrissa_follicle | 0.72017679 |
129 | MP0008260_abnormal_autophagy | 0.71327064 |
130 | MP0005171_absent_coat_pigmentation | 0.71093945 |
131 | MP0000627_abnormal_mammary_gland | 0.70230771 |
132 | MP0003221_abnormal_cardiomyocyte_apopto | 0.69822476 |
133 | MP0004133_heterotaxia | 0.69085535 |
134 | MP0001501_abnormal_sleep_pattern | 0.69071123 |
135 | MP0002184_abnormal_innervation | 0.69046293 |
136 | MP0010386_abnormal_urinary_bladder | 0.68895109 |
137 | MP0003091_abnormal_cell_migration | 0.68833902 |
138 | MP0002092_abnormal_eye_morphology | 0.68651769 |
139 | MP0005330_cardiomyopathy | 0.68004632 |
140 | MP0006072_abnormal_retinal_apoptosis | 0.67639887 |
141 | MP0002572_abnormal_emotion/affect_behav | 0.67557995 |
142 | MP0002019_abnormal_tumor_incidence | 0.67399296 |
143 | MP0001529_abnormal_vocalization | 0.67236460 |
144 | MP0009703_decreased_birth_body | 0.67095561 |
145 | MP0002272_abnormal_nervous_system | 0.66387168 |
146 | MP0000428_abnormal_craniofacial_morphol | 0.65075066 |
147 | MP0000432_abnormal_head_morphology | 0.63938082 |
148 | MP0001216_abnormal_epidermal_layer | 0.62655890 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of the labia minora (HP:0012880) | 4.01327612 |
2 | Multiple enchondromatosis (HP:0005701) | 3.84552006 |
3 | Irregular epiphyses (HP:0010582) | 3.76605197 |
4 | Atonic seizures (HP:0010819) | 3.62525178 |
5 | Resting tremor (HP:0002322) | 3.43732323 |
6 | Chromsome breakage (HP:0040012) | 3.38294513 |
7 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.23089677 |
8 | Cervical subluxation (HP:0003308) | 3.21816646 |
9 | Abnormality of the anterior horn cell (HP:0006802) | 3.11846249 |
10 | Degeneration of anterior horn cells (HP:0002398) | 3.11846249 |
11 | Protrusio acetabuli (HP:0003179) | 3.02265215 |
12 | Shoulder girdle muscle weakness (HP:0003547) | 2.94987177 |
13 | Increased nuchal translucency (HP:0010880) | 2.94986994 |
14 | Hypoplasia of the pons (HP:0012110) | 2.94551470 |
15 | Birth length less than 3rd percentile (HP:0003561) | 2.93163525 |
16 | Abnormality of methionine metabolism (HP:0010901) | 2.90664579 |
17 | Exercise-induced muscle cramps (HP:0003710) | 2.84256989 |
18 | Abnormality of glycolysis (HP:0004366) | 2.82324678 |
19 | Increased serum pyruvate (HP:0003542) | 2.82324678 |
20 | Microvesicular hepatic steatosis (HP:0001414) | 2.80055261 |
21 | Agnosia (HP:0010524) | 2.78284983 |
22 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.76504572 |
23 | Cortical dysplasia (HP:0002539) | 2.72552556 |
24 | Hand muscle atrophy (HP:0009130) | 2.72242932 |
25 | Embryonal renal neoplasm (HP:0011794) | 2.69548754 |
26 | Premature rupture of membranes (HP:0001788) | 2.69524327 |
27 | Insidious onset (HP:0003587) | 2.69360036 |
28 | Termporal pattern (HP:0011008) | 2.69360036 |
29 | Long foot (HP:0001833) | 2.67948623 |
30 | Progressive external ophthalmoplegia (HP:0000590) | 2.55570685 |
31 | Impaired pain sensation (HP:0007328) | 2.51730357 |
32 | Abnormality of pain sensation (HP:0010832) | 2.51730357 |
33 | Cerebral hypomyelination (HP:0006808) | 2.51477884 |
34 | Rhabdomyosarcoma (HP:0002859) | 2.48431685 |
35 | Postnatal microcephaly (HP:0005484) | 2.48038727 |
36 | Spinal cord compression (HP:0002176) | 2.44123864 |
37 | Upper limb muscle weakness (HP:0003484) | 2.43673931 |
38 | Ependymoma (HP:0002888) | 2.43416576 |
39 | Abnormality of the pons (HP:0007361) | 2.41900056 |
40 | Abnormal lung lobation (HP:0002101) | 2.40247703 |
41 | Vertebral compression fractures (HP:0002953) | 2.38316899 |
42 | Colon cancer (HP:0003003) | 2.36266329 |
43 | Abnormality of the astrocytes (HP:0100707) | 2.35697002 |
44 | Astrocytoma (HP:0009592) | 2.35697002 |
45 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.34844291 |
46 | Focal motor seizures (HP:0011153) | 2.34261540 |
47 | Abnormality of the calcaneus (HP:0008364) | 2.34245772 |
48 | Carpal bone hypoplasia (HP:0001498) | 2.33913040 |
49 | Absence seizures (HP:0002121) | 2.33080480 |
50 | Pelvic girdle muscle weakness (HP:0003749) | 2.31999555 |
51 | Distal upper limb amyotrophy (HP:0007149) | 2.30355279 |
52 | Upper limb amyotrophy (HP:0009129) | 2.30355279 |
53 | Abnormality of the umbilical cord (HP:0010881) | 2.30341262 |
54 | Autoamputation (HP:0001218) | 2.26965423 |
55 | Mild short stature (HP:0003502) | 2.26053833 |
56 | Neoplasm of the colon (HP:0100273) | 2.25080600 |
57 | Abnormality of chromosome stability (HP:0003220) | 2.24598181 |
58 | Medulloblastoma (HP:0002885) | 2.24550342 |
59 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 2.23136089 |
60 | Abnormal gallbladder physiology (HP:0012438) | 2.23084866 |
61 | Cholecystitis (HP:0001082) | 2.23084866 |
62 | Pterygium (HP:0001059) | 2.22517396 |
63 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.21608766 |
64 | Absent epiphyses (HP:0010577) | 2.21608766 |
65 | Abnormalities of placenta or umbilical cord (HP:0001194) | 2.21425628 |
66 | Selective tooth agenesis (HP:0001592) | 2.20768911 |
67 | Neoplasm of the adrenal gland (HP:0100631) | 2.18939736 |
68 | Hypoplasia of the odontoid process (HP:0003311) | 2.14400222 |
69 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.13245799 |
70 | Hypoglycemic seizures (HP:0002173) | 2.12768923 |
71 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.11369389 |
72 | Papillary thyroid carcinoma (HP:0002895) | 2.11219760 |
73 | Abnormality of serum amino acid levels (HP:0003112) | 2.08310712 |
74 | Abnormal cartilage morphology (HP:0002763) | 2.07259316 |
75 | Neoplasm of the small intestine (HP:0100833) | 2.06360707 |
76 | Delayed puberty (HP:0000823) | 2.06058900 |
77 | Breech presentation (HP:0001623) | 2.04546537 |
78 | Epiphyseal dysplasia (HP:0002656) | 2.04456279 |
79 | Abnormality of the preputium (HP:0100587) | 2.04267242 |
80 | Emotional lability (HP:0000712) | 2.01561732 |
81 | Hypoglycemic coma (HP:0001325) | 2.01049362 |
82 | Megaloblastic anemia (HP:0001889) | 2.00966549 |
83 | Cutaneous melanoma (HP:0012056) | 2.00881906 |
84 | Meckel diverticulum (HP:0002245) | 2.00107678 |
85 | Vertebral hypoplasia (HP:0008417) | 1.99372294 |
86 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.99372294 |
87 | Neuroblastoma (HP:0003006) | 1.99166869 |
88 | Primitive neuroectodermal tumor (HP:0030065) | 1.99166869 |
89 | Neuroblastic tumors (HP:0004376) | 1.99166869 |
90 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 1.99166869 |
91 | Ankyloglossia (HP:0010296) | 1.99121290 |
92 | Spinal muscular atrophy (HP:0007269) | 1.99112162 |
93 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.98285880 |
94 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.98285880 |
95 | Abnormality of placental membranes (HP:0011409) | 1.97055339 |
96 | Amniotic constriction ring (HP:0009775) | 1.97055339 |
97 | Angiofibromas (HP:0010615) | 1.96194121 |
98 | Adenoma sebaceum (HP:0009720) | 1.96194121 |
99 | Wrist flexion contracture (HP:0001239) | 1.96169854 |
100 | Tongue fasciculations (HP:0001308) | 1.95865471 |
101 | Abnormality of the odontoid process (HP:0003310) | 1.94608877 |
102 | Epileptic encephalopathy (HP:0200134) | 1.94076646 |
103 | Trismus (HP:0000211) | 1.93585985 |
104 | Progressive muscle weakness (HP:0003323) | 1.93314232 |
105 | Spastic diplegia (HP:0001264) | 1.90653999 |
106 | Dialeptic seizures (HP:0011146) | 1.88407832 |
107 | Poor suck (HP:0002033) | 1.88017874 |
108 | Muscle fibrillation (HP:0010546) | 1.87881080 |
109 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.87865067 |
110 | Coxa vara (HP:0002812) | 1.87515751 |
111 | Symptomatic seizures (HP:0011145) | 1.87175470 |
112 | Reduced antithrombin III activity (HP:0001976) | 1.86658094 |
113 | Freckling (HP:0001480) | 1.85267227 |
114 | Deviation of the thumb (HP:0009603) | 1.85147777 |
115 | Neoplasm of the rectum (HP:0100743) | 1.84520256 |
116 | Proximal placement of thumb (HP:0009623) | 1.84435197 |
117 | Ovarian neoplasm (HP:0100615) | 1.83994923 |
118 | Abnormal auditory evoked potentials (HP:0006958) | 1.83627405 |
119 | Increased density of long bones (HP:0006392) | 1.82940725 |
120 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.82312110 |
121 | Disproportionate short-trunk short stature (HP:0003521) | 1.79332959 |
122 | Metaphyseal cupping (HP:0003021) | 1.79218135 |
123 | Abnormality of the ileum (HP:0001549) | 1.78445096 |
124 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.78308360 |
125 | Increased hepatocellular lipid droplets (HP:0006565) | 1.77893771 |
126 | Hammertoe (HP:0001765) | 1.77776689 |
127 | Cupped ribs (HP:0000887) | 1.77711035 |
128 | Ankle contracture (HP:0006466) | 1.77598916 |
129 | Stillbirth (HP:0003826) | 1.77173395 |
130 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.77121883 |
131 | Biliary tract neoplasm (HP:0100574) | 1.77049985 |
132 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.76968634 |
133 | Single umbilical artery (HP:0001195) | 1.76968634 |
134 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.76968634 |
135 | Delayed gross motor development (HP:0002194) | 1.76456894 |
136 | Overlapping toe (HP:0001845) | 1.76299706 |
137 | Uterine neoplasm (HP:0010784) | 1.75896737 |
138 | Small intestinal stenosis (HP:0012848) | 1.75584569 |
139 | Duodenal stenosis (HP:0100867) | 1.75584569 |
140 | Breast hypoplasia (HP:0003187) | 1.75345149 |
141 | Volvulus (HP:0002580) | 1.75274134 |
142 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.75101211 |
143 | Right ventricular cardiomyopathy (HP:0011663) | 1.74785271 |
144 | Sensory axonal neuropathy (HP:0003390) | 1.74178310 |
145 | Glossoptosis (HP:0000162) | 1.72718982 |
146 | Acute necrotizing encephalopathy (HP:0006965) | 1.72591023 |
147 | Rough bone trabeculation (HP:0100670) | 1.72328842 |
148 | Insomnia (HP:0100785) | 1.71893964 |
149 | Abnormality of the lower motor neuron (HP:0002366) | 1.70817981 |
150 | Neuroendocrine neoplasm (HP:0100634) | 1.70803939 |
151 | Athetosis (HP:0002305) | 1.70334825 |
152 | Genu recurvatum (HP:0002816) | 1.70054029 |
153 | Large hands (HP:0001176) | 1.69825313 |
154 | Flat acetabular roof (HP:0003180) | 1.69160561 |
155 | Hyperalaninemia (HP:0003348) | 1.69079743 |
156 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.69079743 |
157 | Abnormality of alanine metabolism (HP:0010916) | 1.69079743 |
158 | Failure to thrive in infancy (HP:0001531) | 1.68982628 |
159 | Glioma (HP:0009733) | 1.68837149 |
160 | Abnormal hair whorl (HP:0010721) | 1.67477147 |
161 | Embryonal neoplasm (HP:0002898) | 1.67294951 |
162 | Breast carcinoma (HP:0003002) | 1.66921633 |
163 | Type I transferrin isoform profile (HP:0003642) | 1.66921613 |
164 | Beaking of vertebral bodies (HP:0004568) | 1.66800054 |
165 | Abnormality of oral frenula (HP:0000190) | 1.66383830 |
166 | Homocystinuria (HP:0002156) | 1.66201562 |
167 | Abnormality of homocysteine metabolism (HP:0010919) | 1.66201562 |
168 | Febrile seizures (HP:0002373) | 1.66177867 |
169 | Pheochromocytoma (HP:0002666) | 1.65919093 |
170 | Focal seizures (HP:0007359) | 1.65880066 |
171 | Palpitations (HP:0001962) | 1.65746303 |
172 | Abnormality of glycine metabolism (HP:0010895) | 1.65613193 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TSSK6 | 4.97731805 |
2 | NEK1 | 3.79019169 |
3 | EIF2AK1 | 3.38137648 |
4 | PBK | 3.35840960 |
5 | EPHA2 | 2.78595090 |
6 | SCYL2 | 2.72682242 |
7 | CDC7 | 2.61174901 |
8 | BUB1 | 2.52844333 |
9 | AKT3 | 2.35300061 |
10 | PLK2 | 2.30404307 |
11 | WEE1 | 2.20976034 |
12 | EIF2AK3 | 2.18819002 |
13 | MAP3K12 | 2.15556011 |
14 | PLK3 | 2.09458888 |
15 | PDK3 | 2.01161182 |
16 | PDK4 | 2.01161182 |
17 | NME1 | 1.88775676 |
18 | TRIM28 | 1.80900608 |
19 | LIMK1 | 1.77693258 |
20 | LATS2 | 1.66119281 |
21 | TESK1 | 1.60709058 |
22 | EEF2K | 1.53782679 |
23 | CASK | 1.52482823 |
24 | MAP3K4 | 1.49877295 |
25 | NTRK3 | 1.44867162 |
26 | PDK2 | 1.44030092 |
27 | BCR | 1.43410327 |
28 | RPS6KB2 | 1.36144221 |
29 | PIM2 | 1.32329630 |
30 | TTK | 1.29148097 |
31 | CCNB1 | 1.28810179 |
32 | ERBB4 | 1.28545035 |
33 | MINK1 | 1.27456702 |
34 | PASK | 1.27380825 |
35 | TESK2 | 1.25692278 |
36 | PNCK | 1.25413065 |
37 | PAK4 | 1.24946318 |
38 | DAPK1 | 1.24044135 |
39 | TAF1 | 1.22036923 |
40 | MST1R | 1.18836478 |
41 | ALK | 1.17478539 |
42 | BRSK2 | 1.16471326 |
43 | LATS1 | 1.13882028 |
44 | DDR2 | 1.11021497 |
45 | CDK6 | 1.07508432 |
46 | BRAF | 1.07434992 |
47 | PLK1 | 1.06330822 |
48 | EIF2AK2 | 1.02830580 |
49 | MAP3K9 | 1.02067837 |
50 | PKN2 | 1.00830848 |
51 | VRK2 | 0.99438812 |
52 | BRSK1 | 0.96236845 |
53 | AURKA | 0.95603863 |
54 | MST4 | 0.94701788 |
55 | ZAK | 0.91837576 |
56 | NEK2 | 0.91116939 |
57 | SRPK1 | 0.85513327 |
58 | CDK8 | 0.83932163 |
59 | MKNK1 | 0.83346657 |
60 | STK3 | 0.81913237 |
61 | MAP2K7 | 0.81710879 |
62 | ERBB3 | 0.79655797 |
63 | MAP3K8 | 0.79088313 |
64 | SMG1 | 0.78408518 |
65 | MAPKAPK3 | 0.76304726 |
66 | MAP2K4 | 0.76030182 |
67 | PDGFRA | 0.75746094 |
68 | STK39 | 0.75719294 |
69 | ARAF | 0.75595120 |
70 | BRD4 | 0.74888296 |
71 | AURKB | 0.74726456 |
72 | CLK1 | 0.74504168 |
73 | RPS6KA4 | 0.72064224 |
74 | MAP3K10 | 0.71554460 |
75 | CDK14 | 0.71022189 |
76 | CHEK1 | 0.70186606 |
77 | ATR | 0.69866664 |
78 | PRKCI | 0.69219789 |
79 | CDK7 | 0.68466774 |
80 | CAMKK2 | 0.67993276 |
81 | TTN | 0.67168844 |
82 | TNIK | 0.67084334 |
83 | CSNK1G1 | 0.66773405 |
84 | CDK18 | 0.66399877 |
85 | NTRK1 | 0.64653995 |
86 | FGFR1 | 0.63632835 |
87 | MAP2K1 | 0.63032539 |
88 | PRKCG | 0.63023296 |
89 | FER | 0.62133678 |
90 | CDK15 | 0.62043267 |
91 | NEK9 | 0.61783607 |
92 | PLK4 | 0.57219912 |
93 | STK10 | 0.55138685 |
94 | CSNK2A2 | 0.54490024 |
95 | CSNK1G3 | 0.54229134 |
96 | RPS6KB1 | 0.53391584 |
97 | TAOK2 | 0.53390858 |
98 | CSNK1E | 0.52298808 |
99 | CAMKK1 | 0.51834508 |
100 | CSNK1A1L | 0.51561578 |
101 | CDK11A | 0.51384148 |
102 | NEK6 | 0.51100863 |
103 | MAPKAPK5 | 0.51027264 |
104 | MAP3K11 | 0.50845566 |
105 | CSNK1G2 | 0.50264986 |
106 | PAK1 | 0.49090318 |
107 | CDK19 | 0.48617603 |
108 | CDK2 | 0.48169608 |
109 | MAP3K3 | 0.48008341 |
110 | STK24 | 0.47426044 |
111 | MAP3K5 | 0.46508438 |
112 | PTK2 | 0.45651196 |
113 | ACVR1B | 0.43889538 |
114 | PRKDC | 0.42157294 |
115 | PAK2 | 0.41619812 |
116 | YES1 | 0.40747843 |
117 | STK16 | 0.40329498 |
118 | VRK1 | 0.40066329 |
119 | NME2 | 0.38570846 |
120 | MET | 0.38543325 |
121 | STK38L | 0.38315289 |
122 | AKT2 | 0.38223740 |
123 | CDK1 | 0.38008876 |
124 | WNK4 | 0.37223655 |
125 | GRK5 | 0.36293967 |
126 | KSR1 | 0.36091060 |
127 | CSNK2A1 | 0.35338573 |
128 | ROCK2 | 0.34991512 |
129 | DMPK | 0.33804341 |
130 | ATM | 0.33786453 |
131 | FLT3 | 0.33436288 |
132 | MKNK2 | 0.33174470 |
133 | CHEK2 | 0.30901769 |
134 | DAPK3 | 0.30700269 |
135 | CDK12 | 0.30105640 |
136 | FRK | 0.29554403 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 4.61400796 |
2 | Proteasome_Homo sapiens_hsa03050 | 3.76032929 |
3 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 3.34061921 |
4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.31948014 |
5 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.92852603 |
6 | RNA transport_Homo sapiens_hsa03013 | 2.89498761 |
7 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.72187283 |
8 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.58251896 |
9 | DNA replication_Homo sapiens_hsa03030 | 2.36686540 |
10 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.30588158 |
11 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.18077533 |
12 | Mismatch repair_Homo sapiens_hsa03430 | 2.09052337 |
13 | RNA polymerase_Homo sapiens_hsa03020 | 1.87064670 |
14 | Spliceosome_Homo sapiens_hsa03040 | 1.86278300 |
15 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.82141203 |
16 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.81644595 |
17 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.80864853 |
18 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.74663366 |
19 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.69119292 |
20 | Cell cycle_Homo sapiens_hsa04110 | 1.68614673 |
21 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.63291265 |
22 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.56603205 |
23 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.42502223 |
24 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.37612937 |
25 | Carbon metabolism_Homo sapiens_hsa01200 | 1.36226966 |
26 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.36034318 |
27 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.35211550 |
28 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.33987454 |
29 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.30424570 |
30 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.30334044 |
31 | Phagosome_Homo sapiens_hsa04145 | 1.23297145 |
32 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.23016903 |
33 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.21904272 |
34 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.21703879 |
35 | Protein export_Homo sapiens_hsa03060 | 1.21452049 |
36 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.16703355 |
37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.10294445 |
38 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.06909411 |
39 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.06881931 |
40 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.06200739 |
41 | Base excision repair_Homo sapiens_hsa03410 | 1.05932942 |
42 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.03127492 |
43 | RNA degradation_Homo sapiens_hsa03018 | 1.01559700 |
44 | Nicotine addiction_Homo sapiens_hsa05033 | 1.01226026 |
45 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.99427773 |
46 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.98606376 |
47 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.97345281 |
48 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.90171761 |
49 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.87275427 |
50 | Adherens junction_Homo sapiens_hsa04520 | 0.87259092 |
51 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.86768378 |
52 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.85650222 |
53 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.84179772 |
54 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.83814401 |
55 | Thyroid cancer_Homo sapiens_hsa05216 | 0.83813506 |
56 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.83137161 |
57 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.82501481 |
58 | Long-term potentiation_Homo sapiens_hsa04720 | 0.82501213 |
59 | Bladder cancer_Homo sapiens_hsa05219 | 0.81597937 |
60 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.80935310 |
61 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.80532290 |
62 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.77772775 |
63 | Galactose metabolism_Homo sapiens_hsa00052 | 0.77365770 |
64 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.76145360 |
65 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.75473104 |
66 | Homologous recombination_Homo sapiens_hsa03440 | 0.75422656 |
67 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.75224951 |
68 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.74669197 |
69 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.74480705 |
70 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.72594460 |
71 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.72494444 |
72 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.72192692 |
73 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.69735303 |
74 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.68898343 |
75 | Basal transcription factors_Homo sapiens_hsa03022 | 0.67185151 |
76 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.66701120 |
77 | Legionellosis_Homo sapiens_hsa05134 | 0.66415068 |
78 | Parkinsons disease_Homo sapiens_hsa05012 | 0.66278888 |
79 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.65022743 |
80 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.64190075 |
81 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.63796935 |
82 | Melanoma_Homo sapiens_hsa05218 | 0.62410992 |
83 | Ribosome_Homo sapiens_hsa03010 | 0.62156862 |
84 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.61365884 |
85 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.61108741 |
86 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.60569831 |
87 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.60490664 |
88 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.59561330 |
89 | Purine metabolism_Homo sapiens_hsa00230 | 0.57369052 |
90 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.56426716 |
91 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.56413080 |
92 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.55850210 |
93 | Huntingtons disease_Homo sapiens_hsa05016 | 0.55326874 |
94 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.54453988 |
95 | Colorectal cancer_Homo sapiens_hsa05210 | 0.51211281 |
96 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.50953084 |
97 | GABAergic synapse_Homo sapiens_hsa04727 | 0.49192034 |
98 | Gap junction_Homo sapiens_hsa04540 | 0.48403542 |
99 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.47596588 |
100 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.46329998 |
101 | Metabolic pathways_Homo sapiens_hsa01100 | 0.44896564 |
102 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.43650974 |
103 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.43601023 |
104 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.42688314 |
105 | Glioma_Homo sapiens_hsa05214 | 0.42686870 |
106 | Lysine degradation_Homo sapiens_hsa00310 | 0.42467932 |
107 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.41645119 |
108 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.40189690 |
109 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.38975141 |
110 | Long-term depression_Homo sapiens_hsa04730 | 0.37245335 |
111 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.36964182 |
112 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.36289841 |
113 | Shigellosis_Homo sapiens_hsa05131 | 0.35879411 |
114 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.31183596 |
115 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.31162413 |
116 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.30277532 |
117 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.30125207 |
118 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.30067378 |
119 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.29790539 |
120 | Endometrial cancer_Homo sapiens_hsa05213 | 0.29733397 |
121 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.28872687 |
122 | Olfactory transduction_Homo sapiens_hsa04740 | 0.27779514 |
123 | Alzheimers disease_Homo sapiens_hsa05010 | 0.25581029 |
124 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.24734758 |
125 | Apoptosis_Homo sapiens_hsa04210 | 0.24421339 |
126 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.22806515 |
127 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.22731393 |
128 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.22064591 |
129 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.21850280 |
130 | HTLV-I infection_Homo sapiens_hsa05166 | 0.21413903 |
131 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.21022800 |
132 | Tight junction_Homo sapiens_hsa04530 | 0.20674554 |
133 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.17766593 |
134 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.17169042 |
135 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.15195414 |
136 | Prostate cancer_Homo sapiens_hsa05215 | 0.14741802 |
137 | Peroxisome_Homo sapiens_hsa04146 | 0.12637141 |