Rank | Gene Set | Z-score |
---|---|---|
1 | vocalization behavior (GO:0071625) | 5.59234841 |
2 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 5.43417141 |
3 | neuron cell-cell adhesion (GO:0007158) | 5.33063150 |
4 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.09742801 |
5 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.83276826 |
6 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.80320311 |
7 | protein localization to synapse (GO:0035418) | 4.65475671 |
8 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.52300098 |
9 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.50891683 |
10 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.29031497 |
11 | synaptic vesicle exocytosis (GO:0016079) | 4.27782102 |
12 | glutamate receptor signaling pathway (GO:0007215) | 4.14427647 |
13 | behavioral response to ethanol (GO:0048149) | 4.14031450 |
14 | presynaptic membrane assembly (GO:0097105) | 4.08725824 |
15 | axonal fasciculation (GO:0007413) | 4.08630336 |
16 | glutamate secretion (GO:0014047) | 4.08131020 |
17 | neuron recognition (GO:0008038) | 4.06611241 |
18 | locomotory exploration behavior (GO:0035641) | 3.99555543 |
19 | postsynaptic membrane organization (GO:0001941) | 3.98450573 |
20 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.98356071 |
21 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.97846229 |
22 | regulation of sarcomere organization (GO:0060297) | 3.96305970 |
23 | synaptic transmission, glutamatergic (GO:0035249) | 3.95732481 |
24 | neuronal action potential propagation (GO:0019227) | 3.92226992 |
25 | dendritic spine morphogenesis (GO:0060997) | 3.85461951 |
26 | synaptic vesicle maturation (GO:0016188) | 3.78861664 |
27 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.78731180 |
28 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.77442480 |
29 | proline transport (GO:0015824) | 3.76663968 |
30 | positive regulation of synapse maturation (GO:0090129) | 3.75169620 |
31 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.71171509 |
32 | neuron-neuron synaptic transmission (GO:0007270) | 3.69245973 |
33 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.64326686 |
34 | regulation of synaptic vesicle transport (GO:1902803) | 3.59600416 |
35 | presynaptic membrane organization (GO:0097090) | 3.57257241 |
36 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.51850677 |
37 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 3.51759396 |
38 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.50553448 |
39 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.48478506 |
40 | regulation of synapse maturation (GO:0090128) | 3.48071356 |
41 | layer formation in cerebral cortex (GO:0021819) | 3.47830828 |
42 | exploration behavior (GO:0035640) | 3.45547421 |
43 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.45547031 |
44 | regulation of postsynaptic membrane potential (GO:0060078) | 3.42169025 |
45 | long-term memory (GO:0007616) | 3.29947673 |
46 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.29687581 |
47 | regulation of synapse structural plasticity (GO:0051823) | 3.28733324 |
48 | behavioral response to nicotine (GO:0035095) | 3.28510752 |
49 | positive regulation of membrane potential (GO:0045838) | 3.27013621 |
50 | synaptic vesicle endocytosis (GO:0048488) | 3.26721762 |
51 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.26594412 |
52 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.25265872 |
53 | neurotransmitter secretion (GO:0007269) | 3.24315622 |
54 | synapse assembly (GO:0007416) | 3.17363145 |
55 | gamma-aminobutyric acid transport (GO:0015812) | 3.16344767 |
56 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.14915383 |
57 | dendrite morphogenesis (GO:0048813) | 3.13025497 |
58 | cell migration in hindbrain (GO:0021535) | 3.12933125 |
59 | long-term synaptic potentiation (GO:0060291) | 3.11564488 |
60 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.10436846 |
61 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.09651439 |
62 | regulation of synaptic plasticity (GO:0048167) | 3.09178897 |
63 | innervation (GO:0060384) | 3.08577896 |
64 | startle response (GO:0001964) | 3.08114488 |
65 | regulation of neurotransmitter secretion (GO:0046928) | 3.07260910 |
66 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.03978336 |
67 | response to auditory stimulus (GO:0010996) | 2.99012364 |
68 | cerebellar granule cell differentiation (GO:0021707) | 2.98874564 |
69 | positive regulation of synapse assembly (GO:0051965) | 2.96515540 |
70 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.95697602 |
71 | regulation of dendritic spine development (GO:0060998) | 2.95371512 |
72 | membrane depolarization (GO:0051899) | 2.94150010 |
73 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.93189873 |
74 | membrane assembly (GO:0071709) | 2.92819664 |
75 | positive regulation of cardiac muscle cell differentiation (GO:2000727) | 2.90494159 |
76 | dendritic spine organization (GO:0097061) | 2.90295780 |
77 | learning (GO:0007612) | 2.87264941 |
78 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 2.83657362 |
79 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.82963309 |
80 | central nervous system neuron axonogenesis (GO:0021955) | 2.82316258 |
81 | negative regulation of protein localization to cell surface (GO:2000009) | 2.82274664 |
82 | regulation of synapse assembly (GO:0051963) | 2.81036904 |
83 | membrane hyperpolarization (GO:0060081) | 2.80365849 |
84 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.77988502 |
85 | regulation of respiratory system process (GO:0044065) | 2.77724120 |
86 | transmission of nerve impulse (GO:0019226) | 2.76060284 |
87 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.74186329 |
88 | regulation of neurotransmitter transport (GO:0051588) | 2.73395074 |
89 | protein K11-linked deubiquitination (GO:0035871) | 2.73361834 |
90 | membrane depolarization during action potential (GO:0086010) | 2.72908322 |
91 | negative regulation of dendrite development (GO:2000171) | 2.72433226 |
92 | dendrite development (GO:0016358) | 2.71998892 |
93 | regulation of hippo signaling (GO:0035330) | 2.71329514 |
94 | regulation of synapse organization (GO:0050807) | 2.71016333 |
95 | regulation of synaptic transmission, GABAergic (GO:0032228) | 2.68496727 |
96 | positive regulation of neurotransmitter transport (GO:0051590) | 2.68333786 |
97 | nerve growth factor signaling pathway (GO:0038180) | 2.68328160 |
98 | auditory behavior (GO:0031223) | 2.68247318 |
99 | synapse organization (GO:0050808) | 2.68068608 |
100 | response to histamine (GO:0034776) | 2.67220897 |
101 | reflex (GO:0060004) | 2.67164061 |
102 | axon extension (GO:0048675) | 2.66171933 |
103 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.66029583 |
104 | neurotransmitter transport (GO:0006836) | 2.65359241 |
105 | neuronal action potential (GO:0019228) | 2.64639373 |
106 | righting reflex (GO:0060013) | 2.63917724 |
107 | behavioral defense response (GO:0002209) | 2.63751982 |
108 | behavioral fear response (GO:0001662) | 2.63751982 |
109 | establishment of nucleus localization (GO:0040023) | 2.63309622 |
110 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.62630299 |
111 | cochlea development (GO:0090102) | 2.61367080 |
112 | negative regulation of neurotransmitter transport (GO:0051589) | 2.61074869 |
113 | positive regulation of dendritic spine development (GO:0060999) | 2.60948190 |
114 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.60923646 |
115 | negative regulation of axon extension (GO:0030517) | 2.60811496 |
116 | tachykinin receptor signaling pathway (GO:0007217) | 2.60753773 |
117 | regulation of synaptic transmission (GO:0050804) | 2.60696108 |
118 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.60153776 |
119 | establishment of protein localization to Golgi (GO:0072600) | 2.58337229 |
120 | neuromuscular synaptic transmission (GO:0007274) | 2.55621122 |
121 | response to gravity (GO:0009629) | 2.55425659 |
122 | negative regulation of mast cell activation (GO:0033004) | 2.49732207 |
123 | alanine transport (GO:0032328) | 2.45971848 |
124 | fear response (GO:0042596) | 2.45184207 |
125 | detection of mechanical stimulus involved in sensory perception (GO:0050974) | 2.44814022 |
126 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.43735695 |
127 | lymphangiogenesis (GO:0001946) | 2.43514466 |
128 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.42989207 |
129 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.42989207 |
130 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.42989207 |
131 | limb development (GO:0060173) | 2.41830105 |
132 | appendage development (GO:0048736) | 2.41830105 |
133 | negative regulation of axon guidance (GO:1902668) | 2.40035467 |
134 | regulation of action potential (GO:0098900) | 2.39405101 |
135 | nucleus localization (GO:0051647) | 2.39389563 |
136 | regulation of axon guidance (GO:1902667) | 2.39195118 |
137 | C4-dicarboxylate transport (GO:0015740) | 2.38201882 |
138 | regulation of pigment cell differentiation (GO:0050932) | 2.37780697 |
139 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 2.37547926 |
140 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.35820437 |
141 | detection of light stimulus involved in visual perception (GO:0050908) | 2.35820437 |
142 | serotonin metabolic process (GO:0042428) | 2.34705668 |
143 | cerebral cortex cell migration (GO:0021795) | 2.34340317 |
144 | positive regulation of muscle hypertrophy (GO:0014742) | 2.33720205 |
145 | positive regulation of cardiac muscle hypertrophy (GO:0010613) | 2.33720205 |
146 | primary amino compound metabolic process (GO:1901160) | 2.33132596 |
147 | negative chemotaxis (GO:0050919) | 2.32608106 |
148 | cardiac myofibril assembly (GO:0055003) | 2.31142563 |
149 | lipid translocation (GO:0034204) | 2.31045614 |
150 | phospholipid translocation (GO:0045332) | 2.31045614 |
151 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.30823596 |
152 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 2.28910956 |
153 | response to pheromone (GO:0019236) | 2.28373538 |
154 | retinal cone cell development (GO:0046549) | 2.27875524 |
155 | sequestering of extracellular ligand from receptor (GO:0035581) | 2.27747629 |
156 | L-amino acid import (GO:0043092) | 2.27032000 |
157 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.26269675 |
158 | pericardium development (GO:0060039) | 2.25677956 |
159 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.24960724 |
160 | Rac protein signal transduction (GO:0016601) | 2.24920692 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.44694461 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 4.24733078 |
3 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.81306551 |
4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.80316032 |
5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.62530658 |
6 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.43812102 |
7 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.41651262 |
8 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.39677540 |
9 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.39677540 |
10 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.32035712 |
11 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.27734396 |
12 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.21296859 |
13 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.20133300 |
14 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.17974569 |
15 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 2.14204813 |
16 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.10941272 |
17 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.08780819 |
18 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.08181790 |
19 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.05047375 |
20 | * ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.04473676 |
21 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.03821784 |
22 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 2.03645034 |
23 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.03608415 |
24 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.03147846 |
25 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.97684043 |
26 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.94456432 |
27 | * PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.89674927 |
28 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.85328044 |
29 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.85225657 |
30 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.82231239 |
31 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.81886234 |
32 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.76658003 |
33 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.74337175 |
34 | * SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.71796898 |
35 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.69534458 |
36 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.66403122 |
37 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.64004312 |
38 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.62824002 |
39 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.62274972 |
40 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.60879171 |
41 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.60776899 |
42 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.60096304 |
43 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.56116809 |
44 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.52565126 |
45 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.51368544 |
46 | AR_25329375_ChIP-Seq_VCAP_Human | 1.51004339 |
47 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.50618611 |
48 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.46451685 |
49 | * EWS_26573619_Chip-Seq_HEK293_Human | 1.45086629 |
50 | STAT3_23295773_ChIP-Seq_U87_Human | 1.44242529 |
51 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.43130261 |
52 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.43010255 |
53 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.41980494 |
54 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.40460363 |
55 | * IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.40428714 |
56 | * CBP_20019798_ChIP-Seq_JUKART_Human | 1.40428714 |
57 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.40092058 |
58 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.40039148 |
59 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.39803139 |
60 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.39685089 |
61 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.38895633 |
62 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.38856595 |
63 | FUS_26573619_Chip-Seq_HEK293_Human | 1.38565461 |
64 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.38418806 |
65 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.36143354 |
66 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.35864294 |
67 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.33892015 |
68 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.33371477 |
69 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.32763432 |
70 | * CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.30223494 |
71 | CJUN_26792858_Chip-Seq_BT549_Human | 1.30060997 |
72 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.29703585 |
73 | TCF4_23295773_ChIP-Seq_U87_Human | 1.28089181 |
74 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.27895636 |
75 | * TP53_16413492_ChIP-PET_HCT116_Human | 1.27750654 |
76 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.27677604 |
77 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.27657239 |
78 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.27657239 |
79 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.26500480 |
80 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.26500480 |
81 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.23225579 |
82 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.22427062 |
83 | KDM2B_26808549_Chip-Seq_REH_Human | 1.21489430 |
84 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.20343653 |
85 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.19947813 |
86 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.19486942 |
87 | * NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.19460532 |
88 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.19279331 |
89 | VDR_22108803_ChIP-Seq_LS180_Human | 1.18866745 |
90 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.18542960 |
91 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.18491657 |
92 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.18151912 |
93 | * AR_19668381_ChIP-Seq_PC3_Human | 1.17713174 |
94 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.17572701 |
95 | * YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.17217863 |
96 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.17074064 |
97 | * TCF4_22108803_ChIP-Seq_LS180_Human | 1.16069319 |
98 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.15587642 |
99 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.14055892 |
100 | * TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.13596958 |
101 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.13572080 |
102 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.12724782 |
103 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.12533282 |
104 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.12513012 |
105 | * FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.11437901 |
106 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.10943056 |
107 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.10288881 |
108 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.10099626 |
109 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.10077364 |
110 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.09564588 |
111 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.08851891 |
112 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.08786236 |
113 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.07667436 |
114 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.05316922 |
115 | * SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.05314743 |
116 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.05254239 |
117 | * PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.05096111 |
118 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.02936353 |
119 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.01732847 |
120 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.01265008 |
121 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.00941826 |
122 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.00399045 |
123 | * MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.99881666 |
124 | * JUN_21703547_ChIP-Seq_K562_Human | 0.99633652 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.54376554 |
2 | MP0003880_abnormal_central_pattern | 4.56504656 |
3 | MP0003635_abnormal_synaptic_transmissio | 3.67236985 |
4 | MP0003950_abnormal_plasma_membrane | 3.45306850 |
5 | MP0004270_analgesia | 3.29242991 |
6 | MP0002063_abnormal_learning/memory/cond | 3.06169561 |
7 | MP0001968_abnormal_touch/_nociception | 3.05566559 |
8 | MP0009745_abnormal_behavioral_response | 3.04067071 |
9 | MP0002064_seizures | 2.87276447 |
10 | MP0009046_muscle_twitch | 2.73863026 |
11 | MP0002572_abnormal_emotion/affect_behav | 2.72220608 |
12 | MP0005423_abnormal_somatic_nervous | 2.63481314 |
13 | MP0002736_abnormal_nociception_after | 2.63149949 |
14 | MP0000569_abnormal_digit_pigmentation | 2.57784418 |
15 | MP0001486_abnormal_startle_reflex | 2.53513073 |
16 | MP0000778_abnormal_nervous_system | 2.50645109 |
17 | MP0002734_abnormal_mechanical_nocicepti | 2.42421968 |
18 | MP0002735_abnormal_chemical_nociception | 2.32902493 |
19 | MP0003787_abnormal_imprinting | 2.20439375 |
20 | MP0002272_abnormal_nervous_system | 2.13926932 |
21 | MP0002067_abnormal_sensory_capabilities | 1.99176507 |
22 | MP0001501_abnormal_sleep_pattern | 1.98531526 |
23 | MP0002184_abnormal_innervation | 1.97685294 |
24 | MP0001440_abnormal_grooming_behavior | 1.95240165 |
25 | MP0002557_abnormal_social/conspecific_i | 1.90358650 |
26 | MP0005646_abnormal_pituitary_gland | 1.86617632 |
27 | MP0006276_abnormal_autonomic_nervous | 1.85409344 |
28 | MP0005645_abnormal_hypothalamus_physiol | 1.80638365 |
29 | MP0002733_abnormal_thermal_nociception | 1.80420425 |
30 | MP0002822_catalepsy | 1.75061099 |
31 | MP0001188_hyperpigmentation | 1.72231108 |
32 | MP0005386_behavior/neurological_phenoty | 1.71049388 |
33 | MP0004924_abnormal_behavior | 1.71049388 |
34 | MP0001970_abnormal_pain_threshold | 1.70774616 |
35 | MP0000749_muscle_degeneration | 1.65159591 |
36 | MP0002102_abnormal_ear_morphology | 1.64047297 |
37 | MP0009780_abnormal_chondrocyte_physiolo | 1.64041947 |
38 | MP0004811_abnormal_neuron_physiology | 1.55361705 |
39 | MP0005503_abnormal_tendon_morphology | 1.52902957 |
40 | MP0003879_abnormal_hair_cell | 1.52071333 |
41 | MP0004858_abnormal_nervous_system | 1.50143133 |
42 | MP0008438_abnormal_cutaneous_collagen | 1.46175961 |
43 | MP0001984_abnormal_olfaction | 1.42950643 |
44 | MP0000955_abnormal_spinal_cord | 1.42947644 |
45 | MP0004043_abnormal_pH_regulation | 1.40322662 |
46 | MP0008569_lethality_at_weaning | 1.38996068 |
47 | MP0006292_abnormal_olfactory_placode | 1.34568429 |
48 | MP0004742_abnormal_vestibular_system | 1.34480032 |
49 | MP0002882_abnormal_neuron_morphology | 1.34141937 |
50 | MP0005171_absent_coat_pigmentation | 1.31161881 |
51 | MP0000427_abnormal_hair_cycle | 1.28876990 |
52 | MP0005253_abnormal_eye_physiology | 1.27692859 |
53 | MP0002066_abnormal_motor_capabilities/c | 1.25821531 |
54 | MP0001529_abnormal_vocalization | 1.23843337 |
55 | MP0003122_maternal_imprinting | 1.23167349 |
56 | MP0004885_abnormal_endolymph | 1.21672016 |
57 | MP0004084_abnormal_cardiac_muscle | 1.21511611 |
58 | MP0004145_abnormal_muscle_electrophysio | 1.20470226 |
59 | MP0002152_abnormal_brain_morphology | 1.19864174 |
60 | MP0005595_abnormal_vascular_smooth | 1.16948848 |
61 | MP0001502_abnormal_circadian_rhythm | 1.16758288 |
62 | MP0003195_calcinosis | 1.12095736 |
63 | MP0009384_cardiac_valve_regurgitation | 1.10310203 |
64 | MP0008004_abnormal_stomach_pH | 1.10006488 |
65 | MP0003045_fibrosis | 1.09700189 |
66 | MP0006072_abnormal_retinal_apoptosis | 1.09300378 |
67 | MP0000538_abnormal_urinary_bladder | 1.07742959 |
68 | MP0000534_abnormal_ureter_morphology | 1.07188212 |
69 | MP0000631_abnormal_neuroendocrine_gland | 1.05820388 |
70 | MP0005187_abnormal_penis_morphology | 1.05818350 |
71 | MP0003633_abnormal_nervous_system | 1.05275522 |
72 | MP0002638_abnormal_pupillary_reflex | 1.02473440 |
73 | MP0002108_abnormal_muscle_morphology | 1.02394171 |
74 | MP0009250_abnormal_appendicular_skeleto | 1.01258409 |
75 | MP0003942_abnormal_urinary_system | 1.01137245 |
76 | MP0000230_abnormal_systemic_arterial | 1.00957746 |
77 | MP0000015_abnormal_ear_pigmentation | 1.00470412 |
78 | MP0010386_abnormal_urinary_bladder | 0.99856303 |
79 | MP0001963_abnormal_hearing_physiology | 0.97674179 |
80 | MP0004142_abnormal_muscle_tone | 0.96812685 |
81 | MP0004134_abnormal_chest_morphology | 0.96382050 |
82 | MP0005620_abnormal_muscle_contractility | 0.93739773 |
83 | MP0003279_aneurysm | 0.93614144 |
84 | MP0001986_abnormal_taste_sensitivity | 0.93589118 |
85 | MP0001177_atelectasis | 0.93171284 |
86 | MP0004085_abnormal_heartbeat | 0.92191422 |
87 | MP0003937_abnormal_limbs/digits/tail_de | 0.91367209 |
88 | MP0001542_abnormal_bone_strength | 0.91310690 |
89 | MP0003631_nervous_system_phenotype | 0.90702233 |
90 | MP0000751_myopathy | 0.88926202 |
91 | MP0002938_white_spotting | 0.88622259 |
92 | MP0005409_darkened_coat_color | 0.88507719 |
93 | MP0002168_other_aberrant_phenotype | 0.88329970 |
94 | MP0009053_abnormal_anal_canal | 0.87421060 |
95 | MP0001905_abnormal_dopamine_level | 0.86787800 |
96 | MP0005195_abnormal_posterior_eye | 0.85768632 |
97 | MP0003861_abnormal_nervous_system | 0.85264107 |
98 | MP0003755_abnormal_palate_morphology | 0.85136474 |
99 | MP0003121_genomic_imprinting | 0.84070968 |
100 | MP0010368_abnormal_lymphatic_system | 0.83617260 |
101 | MP0004484_altered_response_of | 0.83614312 |
102 | MP0005275_abnormal_skin_tensile | 0.83129169 |
103 | MP0003938_abnormal_ear_development | 0.82848857 |
104 | MP0002909_abnormal_adrenal_gland | 0.82437175 |
105 | MP0001958_emphysema | 0.81807653 |
106 | MP0008877_abnormal_DNA_methylation | 0.81440935 |
107 | MP0002069_abnormal_eating/drinking_beha | 0.80449951 |
108 | MP0005174_abnormal_tail_pigmentation | 0.80319530 |
109 | MP0004133_heterotaxia | 0.80216791 |
110 | MP0000639_abnormal_adrenal_gland | 0.79967751 |
111 | MP0004272_abnormal_basement_membrane | 0.79881543 |
112 | MP0000026_abnormal_inner_ear | 0.79554534 |
113 | MP0002752_abnormal_somatic_nervous | 0.79247054 |
114 | MP0003283_abnormal_digestive_organ | 0.79237880 |
115 | MP0002837_dystrophic_cardiac_calcinosis | 0.79052973 |
116 | MP0001299_abnormal_eye_distance/ | 0.78494379 |
117 | MP0006054_spinal_hemorrhage | 0.77638017 |
118 | MP0001485_abnormal_pinna_reflex | 0.76980595 |
119 | MP0005551_abnormal_eye_electrophysiolog | 0.76780533 |
120 | MP0000049_abnormal_middle_ear | 0.75378576 |
121 | MP0003634_abnormal_glial_cell | 0.70022555 |
122 | MP0000566_synostosis | 0.69728129 |
123 | MP0008874_decreased_physiological_sensi | 0.68322121 |
124 | MP0002751_abnormal_autonomic_nervous | 0.67000095 |
125 | MP0002229_neurodegeneration | 0.65519378 |
126 | MP0003329_amyloid_beta_deposits | 0.63829366 |
127 | MP0002234_abnormal_pharynx_morphology | 0.61120848 |
128 | MP0004215_abnormal_myocardial_fiber | 0.61058840 |
129 | MP0003632_abnormal_nervous_system | 0.60483761 |
130 | MP0003137_abnormal_impulse_conducting | 0.58301514 |
131 | MP0003690_abnormal_glial_cell | 0.58139928 |
132 | MP0005394_taste/olfaction_phenotype | 0.57391415 |
133 | MP0005499_abnormal_olfactory_system | 0.57391415 |
134 | MP0010770_preweaning_lethality | 0.57260252 |
135 | MP0002082_postnatal_lethality | 0.57260252 |
136 | MP0008872_abnormal_physiological_respon | 0.56876786 |
137 | MP0001664_abnormal_digestion | 0.56804711 |
138 | MP0003385_abnormal_body_wall | 0.56213742 |
139 | MP0002116_abnormal_craniofacial_bone | 0.55454169 |
140 | MP0001943_abnormal_respiration | 0.54186355 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 7.18352261 |
2 | Focal seizures (HP:0007359) | 5.05491209 |
3 | Epileptic encephalopathy (HP:0200134) | 4.91984446 |
4 | Hyperventilation (HP:0002883) | 4.54885186 |
5 | Febrile seizures (HP:0002373) | 4.44638381 |
6 | Atonic seizures (HP:0010819) | 4.09697272 |
7 | Broad-based gait (HP:0002136) | 3.81594301 |
8 | Myokymia (HP:0002411) | 3.79624155 |
9 | Progressive cerebellar ataxia (HP:0002073) | 3.67566815 |
10 | Visual hallucinations (HP:0002367) | 3.40878931 |
11 | Excessive salivation (HP:0003781) | 3.29259418 |
12 | Drooling (HP:0002307) | 3.29259418 |
13 | Absence seizures (HP:0002121) | 3.19214412 |
14 | Pancreatic cysts (HP:0001737) | 3.16947941 |
15 | Absent speech (HP:0001344) | 3.15508002 |
16 | Aortic aneurysm (HP:0004942) | 3.14767025 |
17 | Dialeptic seizures (HP:0011146) | 3.11798921 |
18 | Generalized tonic-clonic seizures (HP:0002069) | 3.06449012 |
19 | Mutism (HP:0002300) | 3.03423651 |
20 | Hypoplastic ischia (HP:0003175) | 2.95281187 |
21 | Gaze-evoked nystagmus (HP:0000640) | 2.91234710 |
22 | Protruding tongue (HP:0010808) | 2.88476887 |
23 | Aortic dissection (HP:0002647) | 2.80706412 |
24 | Pancreatic fibrosis (HP:0100732) | 2.79978244 |
25 | Abnormality of midbrain morphology (HP:0002418) | 2.77722541 |
26 | Molar tooth sign on MRI (HP:0002419) | 2.77722541 |
27 | Blue irides (HP:0000635) | 2.75994191 |
28 | Amblyopia (HP:0000646) | 2.75496773 |
29 | True hermaphroditism (HP:0010459) | 2.74115813 |
30 | Abnormality of the ischium (HP:0003174) | 2.72619481 |
31 | Keratoconus (HP:0000563) | 2.72197092 |
32 | Increased corneal curvature (HP:0100692) | 2.72197092 |
33 | Aqueductal stenosis (HP:0002410) | 2.71449032 |
34 | Poor eye contact (HP:0000817) | 2.71316429 |
35 | Type 2 muscle fiber atrophy (HP:0003554) | 2.66497316 |
36 | Action tremor (HP:0002345) | 2.66450117 |
37 | Exotropia (HP:0000577) | 2.63996477 |
38 | Genetic anticipation (HP:0003743) | 2.60311497 |
39 | Fatigable weakness (HP:0003473) | 2.53750917 |
40 | Abnormality of the neuromuscular junction (HP:0003398) | 2.53750917 |
41 | Inability to walk (HP:0002540) | 2.52944682 |
42 | Epileptiform EEG discharges (HP:0011182) | 2.51671002 |
43 | Truncal ataxia (HP:0002078) | 2.51154882 |
44 | Generalized hypopigmentation of hair (HP:0011358) | 2.48696365 |
45 | Nephronophthisis (HP:0000090) | 2.44095294 |
46 | Inappropriate behavior (HP:0000719) | 2.43958208 |
47 | Morphological abnormality of the middle ear (HP:0008609) | 2.39862570 |
48 | Fetal akinesia sequence (HP:0001989) | 2.39517770 |
49 | Fair hair (HP:0002286) | 2.38840739 |
50 | Polyphagia (HP:0002591) | 2.37271194 |
51 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.37010313 |
52 | Abnormal eating behavior (HP:0100738) | 2.34580641 |
53 | Obstructive sleep apnea (HP:0002870) | 2.34244566 |
54 | Popliteal pterygium (HP:0009756) | 2.32668683 |
55 | EEG with generalized epileptiform discharges (HP:0011198) | 2.32244027 |
56 | Abnormality of salivation (HP:0100755) | 2.31826366 |
57 | Abnormal social behavior (HP:0012433) | 2.31529481 |
58 | Impaired social interactions (HP:0000735) | 2.31529481 |
59 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.30839914 |
60 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.28197130 |
61 | Cystic liver disease (HP:0006706) | 2.27998236 |
62 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.24588217 |
63 | Progressive inability to walk (HP:0002505) | 2.23851018 |
64 | Gastroesophageal reflux (HP:0002020) | 2.22489419 |
65 | Decreased muscle mass (HP:0003199) | 2.20170081 |
66 | Widely spaced teeth (HP:0000687) | 2.19630709 |
67 | Hypsarrhythmia (HP:0002521) | 2.17039988 |
68 | Attenuation of retinal blood vessels (HP:0007843) | 2.15276499 |
69 | Congenital sensorineural hearing impairment (HP:0008527) | 2.13994706 |
70 | Urethral obstruction (HP:0000796) | 2.13892824 |
71 | Stereotypic behavior (HP:0000733) | 2.13193589 |
72 | Prolonged QT interval (HP:0001657) | 2.12415283 |
73 | Chorioretinal atrophy (HP:0000533) | 2.12009820 |
74 | Abnormality of the renal medulla (HP:0100957) | 2.11471352 |
75 | Narrow nasal bridge (HP:0000446) | 2.10465867 |
76 | Long nose (HP:0003189) | 2.10023822 |
77 | Hemiparesis (HP:0001269) | 2.09773895 |
78 | Aplasia of the musculature (HP:0100854) | 2.09381861 |
79 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.08762197 |
80 | Genital tract atresia (HP:0001827) | 2.08310102 |
81 | Termporal pattern (HP:0011008) | 2.07587839 |
82 | Insidious onset (HP:0003587) | 2.07587839 |
83 | Bulbous nose (HP:0000414) | 2.07398639 |
84 | Gait imbalance (HP:0002141) | 2.05869690 |
85 | Increased number of teeth (HP:0011069) | 2.03199718 |
86 | Dysdiadochokinesis (HP:0002075) | 2.02374604 |
87 | Abnormality of binocular vision (HP:0011514) | 2.00865196 |
88 | Diplopia (HP:0000651) | 2.00865196 |
89 | Type II lissencephaly (HP:0007260) | 1.99915245 |
90 | Dysmetria (HP:0001310) | 1.99578936 |
91 | Abolished electroretinogram (ERG) (HP:0000550) | 1.99547311 |
92 | Impaired smooth pursuit (HP:0007772) | 1.98742089 |
93 | Bile duct proliferation (HP:0001408) | 1.94211109 |
94 | Abnormal biliary tract physiology (HP:0012439) | 1.94211109 |
95 | Intestinal atresia (HP:0011100) | 1.92792489 |
96 | Vaginal atresia (HP:0000148) | 1.92657288 |
97 | Short chin (HP:0000331) | 1.91543154 |
98 | Sleep apnea (HP:0010535) | 1.91154351 |
99 | Abnormal hair whorl (HP:0010721) | 1.89150836 |
100 | Thickened helices (HP:0000391) | 1.89036760 |
101 | Congenital stationary night blindness (HP:0007642) | 1.88815026 |
102 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.88799718 |
103 | Chronic hepatic failure (HP:0100626) | 1.88484136 |
104 | Absent eyebrow (HP:0002223) | 1.88212267 |
105 | Gowers sign (HP:0003391) | 1.88097987 |
106 | Retinal dysplasia (HP:0007973) | 1.87668294 |
107 | Small hand (HP:0200055) | 1.87165859 |
108 | Short foot (HP:0001773) | 1.85454218 |
109 | Midline defect of the nose (HP:0004122) | 1.85441789 |
110 | Muscle fiber atrophy (HP:0100295) | 1.85249334 |
111 | Abnormality of the pubic bones (HP:0003172) | 1.84338735 |
112 | Limb dystonia (HP:0002451) | 1.84195239 |
113 | Autism (HP:0000717) | 1.83657836 |
114 | Arterial tortuosity (HP:0005116) | 1.83652867 |
115 | Open mouth (HP:0000194) | 1.82490201 |
116 | Absent/shortened dynein arms (HP:0200106) | 1.82001334 |
117 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.82001334 |
118 | Abnormality of the renal cortex (HP:0011035) | 1.81538331 |
119 | Limited hip movement (HP:0008800) | 1.81451207 |
120 | Specific learning disability (HP:0001328) | 1.80885805 |
121 | Hemiplegia (HP:0002301) | 1.80276605 |
122 | Ulnar claw (HP:0001178) | 1.79942950 |
123 | Left ventricular hypertrophy (HP:0001712) | 1.79856259 |
124 | Pachygyria (HP:0001302) | 1.79587920 |
125 | Abnormality of the corticospinal tract (HP:0002492) | 1.79088362 |
126 | Depression (HP:0000716) | 1.78273148 |
127 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.77640701 |
128 | Hypoplasia of the brainstem (HP:0002365) | 1.77640701 |
129 | Depressed nasal tip (HP:0000437) | 1.77005787 |
130 | Tented upper lip vermilion (HP:0010804) | 1.76301337 |
131 | Wrist flexion contracture (HP:0001239) | 1.75669237 |
132 | Ankle clonus (HP:0011448) | 1.75109233 |
133 | Supranuclear gaze palsy (HP:0000605) | 1.73998212 |
134 | Abnormality of macular pigmentation (HP:0008002) | 1.73992161 |
135 | Deeply set eye (HP:0000490) | 1.73314409 |
136 | Preaxial foot polydactyly (HP:0001841) | 1.72803387 |
137 | Incomplete penetrance (HP:0003829) | 1.72609748 |
138 | Anosmia (HP:0000458) | 1.69370279 |
139 | Delayed gross motor development (HP:0002194) | 1.68951164 |
140 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.68517341 |
141 | Macroglossia (HP:0000158) | 1.68438673 |
142 | Postural instability (HP:0002172) | 1.67067262 |
143 | Soft skin (HP:0000977) | 1.65731137 |
144 | Overgrowth (HP:0001548) | 1.65037036 |
145 | Hypoplastic iliac wings (HP:0002866) | 1.64972089 |
146 | Bradycardia (HP:0001662) | 1.64409468 |
147 | Optic nerve hypoplasia (HP:0000609) | 1.64226233 |
148 | Vascular tortuosity (HP:0004948) | 1.62919026 |
149 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.62824094 |
150 | Abnormality of the nasal septum (HP:0000419) | 1.62317847 |
151 | Medial flaring of the eyebrow (HP:0010747) | 1.61667604 |
152 | Lower limb asymmetry (HP:0100559) | 1.61016395 |
153 | Lissencephaly (HP:0001339) | 1.60942133 |
154 | Intellectual disability, severe (HP:0010864) | 1.60205914 |
155 | Lower limb muscle weakness (HP:0007340) | 1.59636178 |
156 | Congenital primary aphakia (HP:0007707) | 1.59022949 |
157 | Nephrogenic diabetes insipidus (HP:0009806) | 1.58523695 |
158 | Submucous cleft hard palate (HP:0000176) | 1.57775682 |
159 | Abnormality of the labia minora (HP:0012880) | 1.57520817 |
160 | Cerebral aneurysm (HP:0004944) | 1.57484362 |
161 | Heterochromia iridis (HP:0001100) | 1.57237870 |
162 | Anxiety (HP:0000739) | 1.56801623 |
163 | Hyperthyroidism (HP:0000836) | 1.56718811 |
164 | Postaxial hand polydactyly (HP:0001162) | 1.56666546 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 6.40462430 |
2 | MUSK | 4.93330030 |
3 | MARK1 | 3.87229277 |
4 | NTRK3 | 3.80988922 |
5 | EPHA4 | 3.76302231 |
6 | CASK | 3.72177531 |
7 | MAP3K4 | 3.36442403 |
8 | MAP2K7 | 3.02980496 |
9 | MAP3K9 | 2.62651106 |
10 | PRPF4B | 2.30234409 |
11 | MINK1 | 2.18400156 |
12 | NTRK2 | 2.13478804 |
13 | SIK2 | 2.11096070 |
14 | SIK3 | 2.03686809 |
15 | MAP2K4 | 2.01528428 |
16 | RIPK4 | 1.97032617 |
17 | MAPK13 | 1.95863971 |
18 | KSR1 | 1.87155726 |
19 | DAPK2 | 1.83848501 |
20 | PAK6 | 1.83847821 |
21 | TNIK | 1.83811525 |
22 | PLK2 | 1.79476973 |
23 | MAP3K12 | 1.78421580 |
24 | PINK1 | 1.62477310 |
25 | TAOK3 | 1.48475064 |
26 | GRK7 | 1.44785019 |
27 | MYLK | 1.43181905 |
28 | CAMK1G | 1.41132538 |
29 | PNCK | 1.34893242 |
30 | LIMK1 | 1.30983473 |
31 | SGK2 | 1.24829970 |
32 | CDK5 | 1.24174585 |
33 | LATS2 | 1.23464152 |
34 | DAPK1 | 1.21066160 |
35 | MAP3K6 | 1.20806535 |
36 | NUAK1 | 1.20640105 |
37 | TYRO3 | 1.15066955 |
38 | CAMKK1 | 1.09964347 |
39 | GRK5 | 1.09693758 |
40 | AKT3 | 1.08793865 |
41 | FGFR2 | 1.06306419 |
42 | DMPK | 1.03185165 |
43 | GRK1 | 1.01974271 |
44 | SGK223 | 1.01972917 |
45 | SGK494 | 1.01972917 |
46 | CAMK2A | 0.97980228 |
47 | STK39 | 0.96283949 |
48 | CAMKK2 | 0.95181238 |
49 | CAMK1 | 0.95062463 |
50 | ACVR1B | 0.93594147 |
51 | CDK3 | 0.93569807 |
52 | MAP4K2 | 0.93023092 |
53 | PTK2B | 0.90628709 |
54 | CAMK1D | 0.88166359 |
55 | PIK3CG | 0.87442024 |
56 | CDK19 | 0.84718271 |
57 | CCNB1 | 0.83217389 |
58 | PRKD3 | 0.81506947 |
59 | PRKCG | 0.81429301 |
60 | SGK3 | 0.80924130 |
61 | ROCK1 | 0.79368703 |
62 | STK38 | 0.79022896 |
63 | FES | 0.78494499 |
64 | DYRK1A | 0.78342460 |
65 | RET | 0.77306576 |
66 | BMPR2 | 0.76420428 |
67 | CAMK4 | 0.75560778 |
68 | UHMK1 | 0.75396630 |
69 | NTRK1 | 0.74162466 |
70 | SGK1 | 0.73599225 |
71 | TGFBR2 | 0.70195867 |
72 | CAMK2B | 0.69504360 |
73 | STK11 | 0.69057768 |
74 | KSR2 | 0.67858447 |
75 | MARK2 | 0.67036271 |
76 | FGR | 0.65418114 |
77 | CSNK1A1L | 0.65142650 |
78 | PRKCE | 0.64248574 |
79 | CDK18 | 0.63777321 |
80 | WNK4 | 0.61811908 |
81 | LATS1 | 0.59597956 |
82 | BMPR1B | 0.59010387 |
83 | FER | 0.58276325 |
84 | CSNK1G2 | 0.58104883 |
85 | FLT3 | 0.57192135 |
86 | CDK15 | 0.55951204 |
87 | DYRK2 | 0.54898788 |
88 | PHKG1 | 0.54104562 |
89 | PHKG2 | 0.54104562 |
90 | PAK3 | 0.53704192 |
91 | WNK1 | 0.52871321 |
92 | TAOK2 | 0.50645396 |
93 | EPHB2 | 0.50371500 |
94 | NEK6 | 0.50081471 |
95 | MKNK2 | 0.49073116 |
96 | STK38L | 0.48654796 |
97 | TRPM7 | 0.48387628 |
98 | OXSR1 | 0.48226646 |
99 | YES1 | 0.48023889 |
100 | PRKCZ | 0.47885615 |
101 | TRIM28 | 0.47438603 |
102 | CDK11A | 0.47051814 |
103 | CDK8 | 0.46955810 |
104 | PKN1 | 0.46356042 |
105 | CDC42BPA | 0.46336206 |
106 | MET | 0.45784495 |
107 | TIE1 | 0.45163790 |
108 | MAPK12 | 0.45103491 |
109 | CAMK2D | 0.44444357 |
110 | INSRR | 0.44418978 |
111 | RAF1 | 0.44418251 |
112 | CDK14 | 0.44310372 |
113 | ADRBK2 | 0.43049260 |
114 | PDGFRB | 0.42574950 |
115 | BCR | 0.42474893 |
116 | PDGFRA | 0.42416331 |
117 | PTK2 | 0.42376068 |
118 | PAK2 | 0.41502794 |
119 | PRKACB | 0.40733877 |
120 | ERBB3 | 0.40642367 |
121 | ERBB4 | 0.39948225 |
122 | CSNK1D | 0.39769322 |
123 | WNK3 | 0.39438158 |
124 | PRKCH | 0.39320998 |
125 | TGFBR1 | 0.38733641 |
126 | ROCK2 | 0.38339669 |
127 | ABL1 | 0.37876992 |
128 | MAPK15 | 0.37415697 |
129 | PIK3CA | 0.37362611 |
130 | MAP2K1 | 0.37300955 |
131 | CSNK1G1 | 0.37201855 |
132 | PRKG1 | 0.37034571 |
133 | MAPK10 | 0.36974207 |
134 | MAPKAPK5 | 0.36730685 |
135 | DDR2 | 0.35281371 |
136 | RPS6KA3 | 0.35221862 |
137 | ADRBK1 | 0.35045730 |
138 | PRKAA1 | 0.34989146 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.76927231 |
2 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.71043323 |
3 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.61359407 |
4 | Circadian entrainment_Homo sapiens_hsa04713 | 2.46694285 |
5 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.45798729 |
6 | Long-term potentiation_Homo sapiens_hsa04720 | 2.39927408 |
7 | Morphine addiction_Homo sapiens_hsa05032 | 2.35014267 |
8 | Olfactory transduction_Homo sapiens_hsa04740 | 2.32849037 |
9 | GABAergic synapse_Homo sapiens_hsa04727 | 2.28604215 |
10 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.20927995 |
11 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.98466862 |
12 | Salivary secretion_Homo sapiens_hsa04970 | 1.97148716 |
13 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.83288101 |
14 | Taste transduction_Homo sapiens_hsa04742 | 1.80529455 |
15 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.75084923 |
16 | Long-term depression_Homo sapiens_hsa04730 | 1.74268069 |
17 | Renin secretion_Homo sapiens_hsa04924 | 1.73082446 |
18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.73034233 |
19 | Axon guidance_Homo sapiens_hsa04360 | 1.72959116 |
20 | Insulin secretion_Homo sapiens_hsa04911 | 1.72215895 |
21 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.65071846 |
22 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.59626679 |
23 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.55894413 |
24 | Cocaine addiction_Homo sapiens_hsa05030 | 1.55111750 |
25 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.54497496 |
26 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.45089720 |
27 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.44984125 |
28 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.44639473 |
29 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.38340073 |
30 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.36528967 |
31 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.33590998 |
32 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.29647524 |
33 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.29087156 |
34 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.26790346 |
35 | Gap junction_Homo sapiens_hsa04540 | 1.26546969 |
36 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.20954554 |
37 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.19037939 |
38 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.15479655 |
39 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.14835800 |
40 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.14811361 |
41 | Glioma_Homo sapiens_hsa05214 | 1.13951843 |
42 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.09401585 |
43 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.09108136 |
44 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.08615785 |
45 | Melanogenesis_Homo sapiens_hsa04916 | 1.08302153 |
46 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.04876251 |
47 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.03792246 |
48 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.03724455 |
49 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.03246325 |
50 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.95226285 |
51 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.94696265 |
52 | ABC transporters_Homo sapiens_hsa02010 | 0.93614400 |
53 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.93003770 |
54 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.92454606 |
55 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.90981497 |
56 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.87791018 |
57 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.87326693 |
58 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.87195585 |
59 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.86837893 |
60 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.86231425 |
61 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.86029948 |
62 | Focal adhesion_Homo sapiens_hsa04510 | 0.84175555 |
63 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.83309280 |
64 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.83208142 |
65 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.82284459 |
66 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.81764736 |
67 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.80202396 |
68 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.80031554 |
69 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.79589033 |
70 | Phototransduction_Homo sapiens_hsa04744 | 0.79269426 |
71 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.78620238 |
72 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.78160175 |
73 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.76670113 |
74 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.74500143 |
75 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.74429734 |
76 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.73987617 |
77 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.73779033 |
78 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.72603793 |
79 | Colorectal cancer_Homo sapiens_hsa05210 | 0.71957880 |
80 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.67903475 |
81 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.66079321 |
82 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.65973796 |
83 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.65457019 |
84 | Endometrial cancer_Homo sapiens_hsa05213 | 0.65317350 |
85 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.63205469 |
86 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.62964770 |
87 | Tight junction_Homo sapiens_hsa04530 | 0.62883307 |
88 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.61868537 |
89 | Circadian rhythm_Homo sapiens_hsa04710 | 0.61860528 |
90 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.61855143 |
91 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.60816173 |
92 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.60392817 |
93 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.60034615 |
94 | Lysine degradation_Homo sapiens_hsa00310 | 0.59388829 |
95 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.58637384 |
96 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.57726191 |
97 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.57720577 |
98 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.57209606 |
99 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.56310561 |
100 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.53832005 |
101 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.53739517 |
102 | Melanoma_Homo sapiens_hsa05218 | 0.53259168 |
103 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.53254076 |
104 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.51852816 |
105 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.51434122 |
106 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.51411485 |
107 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.49250089 |
108 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.49212405 |
109 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.49070735 |
110 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.48657705 |
111 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.48641460 |
112 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.47918622 |
113 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.46181599 |
114 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.46098811 |
115 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.45720596 |
116 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.45156398 |
117 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.44476645 |
118 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.44144865 |
119 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.42843200 |
120 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.42627452 |
121 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.41410714 |
122 | Adherens junction_Homo sapiens_hsa04520 | 0.40616133 |
123 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.40335157 |
124 | Prion diseases_Homo sapiens_hsa05020 | 0.40223468 |
125 | Endocytosis_Homo sapiens_hsa04144 | 0.39758120 |
126 | Basal transcription factors_Homo sapiens_hsa03022 | 0.39720564 |
127 | Retinol metabolism_Homo sapiens_hsa00830 | 0.37933809 |
128 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.37770213 |
129 | Platelet activation_Homo sapiens_hsa04611 | 0.37505422 |
130 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.36255311 |
131 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.35215157 |
132 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.35174026 |
133 | Histidine metabolism_Homo sapiens_hsa00340 | 0.34891416 |
134 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.34777723 |
135 | Protein export_Homo sapiens_hsa03060 | 0.34431874 |
136 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.33611240 |