

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 6.04126717 |
| 2 | ribosomal small subunit assembly (GO:0000028) | 5.88358457 |
| 3 | regulation of mitochondrial translation (GO:0070129) | 5.62651143 |
| 4 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 5.22078435 |
| 5 | pyrimidine nucleotide catabolic process (GO:0006244) | 4.99495301 |
| 6 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.99413999 |
| 7 | ATP synthesis coupled proton transport (GO:0015986) | 4.83698089 |
| 8 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.83698089 |
| 9 | maturation of SSU-rRNA (GO:0030490) | 4.83111874 |
| 10 | deoxyribonucleotide catabolic process (GO:0009264) | 4.82004512 |
| 11 | protein complex biogenesis (GO:0070271) | 4.78795862 |
| 12 | pseudouridine synthesis (GO:0001522) | 4.64001808 |
| 13 | ribosomal small subunit biogenesis (GO:0042274) | 4.62173538 |
| 14 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 4.55563053 |
| 15 | base-excision repair, AP site formation (GO:0006285) | 4.55138037 |
| 16 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.53390211 |
| 17 | deoxyribose phosphate catabolic process (GO:0046386) | 4.52688446 |
| 18 | viral transcription (GO:0019083) | 4.50926583 |
| 19 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.38324992 |
| 20 | translational termination (GO:0006415) | 4.37902606 |
| 21 | iron-sulfur cluster assembly (GO:0016226) | 4.23221498 |
| 22 | metallo-sulfur cluster assembly (GO:0031163) | 4.23221498 |
| 23 | respiratory electron transport chain (GO:0022904) | 4.22545765 |
| 24 | DNA deamination (GO:0045006) | 4.15625187 |
| 25 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.15097955 |
| 26 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.15097955 |
| 27 | NADH dehydrogenase complex assembly (GO:0010257) | 4.15097955 |
| 28 | electron transport chain (GO:0022900) | 4.13069324 |
| 29 | cytochrome complex assembly (GO:0017004) | 4.12882402 |
| 30 | translational elongation (GO:0006414) | 4.05292691 |
| 31 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.01656376 |
| 32 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.99939628 |
| 33 | chaperone-mediated protein transport (GO:0072321) | 3.97410847 |
| 34 | cotranslational protein targeting to membrane (GO:0006613) | 3.92719738 |
| 35 | protein targeting to ER (GO:0045047) | 3.89919026 |
| 36 | respiratory chain complex IV assembly (GO:0008535) | 3.84610757 |
| 37 | proteasome assembly (GO:0043248) | 3.83261488 |
| 38 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.81784371 |
| 39 | protein localization to endoplasmic reticulum (GO:0070972) | 3.80418968 |
| 40 | peptidyl-histidine modification (GO:0018202) | 3.75704947 |
| 41 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 3.73665622 |
| 42 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.68991891 |
| 43 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.66899606 |
| 44 | cellular component biogenesis (GO:0044085) | 3.60265328 |
| 45 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.59727960 |
| 46 | oxidative phosphorylation (GO:0006119) | 3.59568803 |
| 47 | deoxyribose phosphate metabolic process (GO:0019692) | 3.54997198 |
| 48 | protein targeting to mitochondrion (GO:0006626) | 3.54309410 |
| 49 | ribosomal large subunit biogenesis (GO:0042273) | 3.52730398 |
| 50 | viral life cycle (GO:0019058) | 3.52711990 |
| 51 | translation (GO:0006412) | 3.51851438 |
| 52 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.48722547 |
| 53 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.48722547 |
| 54 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.45579739 |
| 55 | translational initiation (GO:0006413) | 3.45511617 |
| 56 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.45386388 |
| 57 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.42993970 |
| 58 | lipopolysaccharide biosynthetic process (GO:0009103) | 3.40143169 |
| 59 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.39196389 |
| 60 | mannosylation (GO:0097502) | 3.38505693 |
| 61 | rRNA modification (GO:0000154) | 3.36467418 |
| 62 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.36105912 |
| 63 | establishment of protein localization to mitochondrion (GO:0072655) | 3.34913366 |
| 64 | cellular protein complex disassembly (GO:0043624) | 3.34685508 |
| 65 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.34217518 |
| 66 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.31616986 |
| 67 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.28073783 |
| 68 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 3.26314604 |
| 69 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.22971249 |
| 70 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.22971249 |
| 71 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.22971249 |
| 72 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.22429931 |
| 73 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.22429931 |
| 74 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.21370345 |
| 75 | negative regulation of ligase activity (GO:0051352) | 3.21370345 |
| 76 | deoxyribonucleotide metabolic process (GO:0009262) | 3.16448348 |
| 77 | negative regulation of telomere maintenance (GO:0032205) | 3.16342225 |
| 78 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.14417544 |
| 79 | protein localization to mitochondrion (GO:0070585) | 3.13369981 |
| 80 | ubiquinone biosynthetic process (GO:0006744) | 3.12720668 |
| 81 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.12282888 |
| 82 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.12282888 |
| 83 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.08655137 |
| 84 | purine deoxyribonucleotide metabolic process (GO:0009151) | 3.07123959 |
| 85 | spliceosomal snRNP assembly (GO:0000387) | 3.05693563 |
| 86 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.02521719 |
| 87 | termination of RNA polymerase III transcription (GO:0006386) | 3.02521719 |
| 88 | maturation of 5.8S rRNA (GO:0000460) | 3.01919237 |
| 89 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 2.99797281 |
| 90 | deoxyribose phosphate biosynthetic process (GO:0046385) | 2.99797281 |
| 91 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.98009997 |
| 92 | protein complex disassembly (GO:0043241) | 2.97709469 |
| 93 | rRNA processing (GO:0006364) | 2.97704814 |
| 94 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.94572633 |
| 95 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.93626513 |
| 96 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.92482958 |
| 97 | protein deneddylation (GO:0000338) | 2.91869053 |
| 98 | pentose metabolic process (GO:0019321) | 2.91818349 |
| 99 | macromolecular complex disassembly (GO:0032984) | 2.91499054 |
| 100 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.90425480 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.12128408 |
| 2 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.03085544 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.00337292 |
| 4 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.50282869 |
| 5 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.47694602 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.37420853 |
| 7 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.30660455 |
| 8 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.25849409 |
| 9 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.21234339 |
| 10 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.18742684 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.05137876 |
| 12 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.98497630 |
| 13 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.71583535 |
| 14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.67589782 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.50281903 |
| 16 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.49717988 |
| 17 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.49039634 |
| 18 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.48228866 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.45448045 |
| 20 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.43869875 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.41506907 |
| 22 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.37754631 |
| 23 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.36876317 |
| 24 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.35225410 |
| 25 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.17899800 |
| 26 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.06347667 |
| 27 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.06227322 |
| 28 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 2.02441202 |
| 29 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.99400711 |
| 30 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.98142397 |
| 31 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.93100715 |
| 32 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.91211759 |
| 33 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.89937593 |
| 34 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.82269244 |
| 35 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.81187338 |
| 36 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.81037767 |
| 37 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.76246520 |
| 38 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.72221128 |
| 39 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.66233544 |
| 40 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.61506417 |
| 41 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.56869241 |
| 42 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.54691681 |
| 43 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.54669201 |
| 44 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.54175919 |
| 45 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.52541901 |
| 46 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.50437223 |
| 47 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.50428324 |
| 48 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.46825665 |
| 49 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.46372771 |
| 50 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.45463546 |
| 51 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.40765589 |
| 52 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.35236386 |
| 53 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.33200449 |
| 54 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.32549031 |
| 55 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.31229369 |
| 56 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.31061706 |
| 57 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.30737393 |
| 58 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.30424354 |
| 59 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.30211885 |
| 60 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.29308800 |
| 61 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.27759745 |
| 62 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.26335554 |
| 63 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.26280492 |
| 64 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.25389986 |
| 65 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.25154697 |
| 66 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.24309794 |
| 67 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.20110818 |
| 68 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.19657027 |
| 69 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.19570954 |
| 70 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.18989606 |
| 71 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.18799299 |
| 72 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.17847081 |
| 73 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.15392169 |
| 74 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.13022630 |
| 75 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.12175018 |
| 76 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.11059646 |
| 77 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.10795261 |
| 78 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.10686169 |
| 79 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.10527424 |
| 80 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.09882787 |
| 81 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.09141676 |
| 82 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.08895695 |
| 83 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.07531641 |
| 84 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.04911823 |
| 85 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.04107176 |
| 86 | P68_20966046_ChIP-Seq_HELA_Human | 1.03146941 |
| 87 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.01038092 |
| 88 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.00068781 |
| 89 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.97951130 |
| 90 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.97619903 |
| 91 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.95371823 |
| 92 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.95338575 |
| 93 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.94230682 |
| 94 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.93577234 |
| 95 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.93398114 |
| 96 | MAF_26560356_Chip-Seq_TH2_Human | 0.92353017 |
| 97 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.92185232 |
| 98 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.91359188 |
| 99 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.89668083 |
| 100 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.89312166 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003806_abnormal_nucleotide_metabolis | 3.32235048 |
| 2 | MP0008058_abnormal_DNA_repair | 3.15215317 |
| 3 | MP0009379_abnormal_foot_pigmentation | 2.97061646 |
| 4 | MP0006292_abnormal_olfactory_placode | 2.80189550 |
| 5 | MP0005075_abnormal_melanosome_morpholog | 2.55094657 |
| 6 | MP0000372_irregular_coat_pigmentation | 2.51019747 |
| 7 | MP0006036_abnormal_mitochondrial_physio | 2.35727147 |
| 8 | MP0003186_abnormal_redox_activity | 2.25474710 |
| 9 | MP0002653_abnormal_ependyma_morphology | 2.23160041 |
| 10 | MP0010094_abnormal_chromosome_stability | 2.22565316 |
| 11 | MP0003646_muscle_fatigue | 2.20622578 |
| 12 | MP0001529_abnormal_vocalization | 2.16356357 |
| 13 | MP0003693_abnormal_embryo_hatching | 2.15348465 |
| 14 | MP0005646_abnormal_pituitary_gland | 2.11952568 |
| 15 | MP0003786_premature_aging | 2.02877929 |
| 16 | MP0003122_maternal_imprinting | 1.92535512 |
| 17 | MP0008789_abnormal_olfactory_epithelium | 1.90121876 |
| 18 | MP0001905_abnormal_dopamine_level | 1.87974047 |
| 19 | MP0003121_genomic_imprinting | 1.85444667 |
| 20 | MP0002837_dystrophic_cardiac_calcinosis | 1.84524317 |
| 21 | MP0003880_abnormal_central_pattern | 1.79657609 |
| 22 | MP0003136_yellow_coat_color | 1.74866741 |
| 23 | MP0008995_early_reproductive_senescence | 1.74052547 |
| 24 | MP0005645_abnormal_hypothalamus_physiol | 1.73373111 |
| 25 | MP0003123_paternal_imprinting | 1.66572621 |
| 26 | MP0001968_abnormal_touch/_nociception | 1.65016955 |
| 27 | MP0006035_abnormal_mitochondrial_morpho | 1.64892290 |
| 28 | MP0008877_abnormal_DNA_methylation | 1.64120432 |
| 29 | MP0004147_increased_porphyrin_level | 1.62088662 |
| 30 | MP0006276_abnormal_autonomic_nervous | 1.54390871 |
| 31 | MP0002277_abnormal_respiratory_mucosa | 1.52596292 |
| 32 | MP0003111_abnormal_nucleus_morphology | 1.50213214 |
| 33 | MP0004142_abnormal_muscle_tone | 1.45314447 |
| 34 | MP0008007_abnormal_cellular_replicative | 1.43917942 |
| 35 | MP0002736_abnormal_nociception_after | 1.43675368 |
| 36 | MP0002163_abnormal_gland_morphology | 1.41720614 |
| 37 | MP0001986_abnormal_taste_sensitivity | 1.41577020 |
| 38 | MP0003787_abnormal_imprinting | 1.39148511 |
| 39 | MP0001764_abnormal_homeostasis | 1.38601606 |
| 40 | MP0008875_abnormal_xenobiotic_pharmacok | 1.37766972 |
| 41 | MP0002095_abnormal_skin_pigmentation | 1.37206123 |
| 42 | MP0005499_abnormal_olfactory_system | 1.37110904 |
| 43 | MP0005394_taste/olfaction_phenotype | 1.37110904 |
| 44 | MP0001727_abnormal_embryo_implantation | 1.33267846 |
| 45 | MP0001853_heart_inflammation | 1.32912883 |
| 46 | MP0004957_abnormal_blastocyst_morpholog | 1.30567405 |
| 47 | MP0003718_maternal_effect | 1.28472291 |
| 48 | MP0005671_abnormal_response_to | 1.27285242 |
| 49 | MP0009333_abnormal_splenocyte_physiolog | 1.23197801 |
| 50 | MP0002876_abnormal_thyroid_physiology | 1.22656607 |
| 51 | MP0008872_abnormal_physiological_respon | 1.19374265 |
| 52 | MP0002160_abnormal_reproductive_system | 1.19099007 |
| 53 | MP0003077_abnormal_cell_cycle | 1.15250687 |
| 54 | MP0008932_abnormal_embryonic_tissue | 1.15067895 |
| 55 | MP0006072_abnormal_retinal_apoptosis | 1.13906983 |
| 56 | MP0002822_catalepsy | 1.13568152 |
| 57 | MP0002132_abnormal_respiratory_system | 1.13149386 |
| 58 | MP0009278_abnormal_bone_marrow | 1.09126008 |
| 59 | MP0005379_endocrine/exocrine_gland_phen | 1.04289048 |
| 60 | MP0009046_muscle_twitch | 1.02804960 |
| 61 | MP0001984_abnormal_olfaction | 1.02547993 |
| 62 | MP0005389_reproductive_system_phenotype | 0.99101429 |
| 63 | MP0005423_abnormal_somatic_nervous | 0.96300500 |
| 64 | MP0005084_abnormal_gallbladder_morpholo | 0.96079825 |
| 65 | MP0001835_abnormal_antigen_presentation | 0.93807724 |
| 66 | MP0004858_abnormal_nervous_system | 0.93378408 |
| 67 | MP0004145_abnormal_muscle_electrophysio | 0.92465419 |
| 68 | MP0005551_abnormal_eye_electrophysiolog | 0.92396131 |
| 69 | MP0000631_abnormal_neuroendocrine_gland | 0.91631935 |
| 70 | MP0005670_abnormal_white_adipose | 0.91243740 |
| 71 | MP0000015_abnormal_ear_pigmentation | 0.91171747 |
| 72 | MP0002102_abnormal_ear_morphology | 0.90889952 |
| 73 | MP0001293_anophthalmia | 0.90491748 |
| 74 | MP0001919_abnormal_reproductive_system | 0.89193232 |
| 75 | MP0002148_abnormal_hypersensitivity_rea | 0.86852740 |
| 76 | MP0005397_hematopoietic_system_phenotyp | 0.86390643 |
| 77 | MP0001545_abnormal_hematopoietic_system | 0.86390643 |
| 78 | MP0003315_abnormal_perineum_morphology | 0.85463237 |
| 79 | MP0005451_abnormal_body_composition | 0.84626424 |
| 80 | MP0002210_abnormal_sex_determination | 0.82368212 |
| 81 | MP0005410_abnormal_fertilization | 0.81433798 |
| 82 | MP0002019_abnormal_tumor_incidence | 0.80839670 |
| 83 | MP0005636_abnormal_mineral_homeostasis | 0.80813704 |
| 84 | MP0000313_abnormal_cell_death | 0.80786238 |
| 85 | MP0000358_abnormal_cell_content/ | 0.79901313 |
| 86 | MP0001929_abnormal_gametogenesis | 0.78461287 |
| 87 | MP0005266_abnormal_metabolism | 0.76908823 |
| 88 | MP0001145_abnormal_male_reproductive | 0.75446429 |
| 89 | MP0000049_abnormal_middle_ear | 0.73831914 |
| 90 | MP0000689_abnormal_spleen_morphology | 0.73575944 |
| 91 | MP0004133_heterotaxia | 0.73290056 |
| 92 | MP0002938_white_spotting | 0.72852637 |
| 93 | MP0000639_abnormal_adrenal_gland | 0.71159911 |
| 94 | MP0002398_abnormal_bone_marrow | 0.70205803 |
| 95 | MP0003011_delayed_dark_adaptation | 0.69888449 |
| 96 | MP0000653_abnormal_sex_gland | 0.68005563 |
| 97 | MP0003567_abnormal_fetal_cardiomyocyte | 0.67899018 |
| 98 | MP0002722_abnormal_immune_system | 0.67891693 |
| 99 | MP0001661_extended_life_span | 0.67184073 |
| 100 | MP0001485_abnormal_pinna_reflex | 0.65767312 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.22398634 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 5.15892990 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.94467447 |
| 4 | Hepatocellular necrosis (HP:0001404) | 4.90143056 |
| 5 | Acute encephalopathy (HP:0006846) | 4.64674059 |
| 6 | Increased CSF lactate (HP:0002490) | 4.58292270 |
| 7 | Hepatic necrosis (HP:0002605) | 4.42975333 |
| 8 | Increased intramyocellular lipid droplets (HP:0012240) | 4.18117653 |
| 9 | Progressive macrocephaly (HP:0004481) | 4.14545634 |
| 10 | Microvesicular hepatic steatosis (HP:0001414) | 4.10632193 |
| 11 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.94346198 |
| 12 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.94346198 |
| 13 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.90029914 |
| 14 | Increased muscle lipid content (HP:0009058) | 3.88496526 |
| 15 | Abnormal number of erythroid precursors (HP:0012131) | 3.56832422 |
| 16 | Increased serum lactate (HP:0002151) | 3.55304549 |
| 17 | Increased hepatocellular lipid droplets (HP:0006565) | 3.52548365 |
| 18 | Lipid accumulation in hepatocytes (HP:0006561) | 3.49950309 |
| 19 | Reticulocytopenia (HP:0001896) | 3.47188460 |
| 20 | Cerebral edema (HP:0002181) | 3.39865421 |
| 21 | Lactic acidosis (HP:0003128) | 3.36973876 |
| 22 | 3-Methylglutaconic aciduria (HP:0003535) | 3.12871744 |
| 23 | Exercise intolerance (HP:0003546) | 3.06152946 |
| 24 | Renal Fanconi syndrome (HP:0001994) | 2.99335879 |
| 25 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.97740676 |
| 26 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.97740676 |
| 27 | Abnormal protein glycosylation (HP:0012346) | 2.97740676 |
| 28 | Abnormal glycosylation (HP:0012345) | 2.97740676 |
| 29 | Hyperglycinemia (HP:0002154) | 2.91958944 |
| 30 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.89909231 |
| 31 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.87116130 |
| 32 | Type I transferrin isoform profile (HP:0003642) | 2.85251831 |
| 33 | Progressive microcephaly (HP:0000253) | 2.82515033 |
| 34 | Respiratory failure (HP:0002878) | 2.70547671 |
| 35 | Aplastic anemia (HP:0001915) | 2.66682479 |
| 36 | Cerebral hypomyelination (HP:0006808) | 2.59972372 |
| 37 | Dicarboxylic aciduria (HP:0003215) | 2.59308430 |
| 38 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.59308430 |
| 39 | Optic disc pallor (HP:0000543) | 2.56741361 |
| 40 | Emotional lability (HP:0000712) | 2.55462066 |
| 41 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.54605698 |
| 42 | Lethargy (HP:0001254) | 2.54009614 |
| 43 | Absent thumb (HP:0009777) | 2.52196983 |
| 44 | Respiratory difficulties (HP:0002880) | 2.47759684 |
| 45 | CNS demyelination (HP:0007305) | 2.43240702 |
| 46 | Failure to thrive in infancy (HP:0001531) | 2.37664252 |
| 47 | Pancytopenia (HP:0001876) | 2.34344683 |
| 48 | Ragged-red muscle fibers (HP:0003200) | 2.30690277 |
| 49 | Abnormality of alanine metabolism (HP:0010916) | 2.27157863 |
| 50 | Hyperalaninemia (HP:0003348) | 2.27157863 |
| 51 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.27157863 |
| 52 | Macrocytic anemia (HP:0001972) | 2.26175749 |
| 53 | Microretrognathia (HP:0000308) | 2.25359514 |
| 54 | Colon cancer (HP:0003003) | 2.19117854 |
| 55 | Exertional dyspnea (HP:0002875) | 2.17422018 |
| 56 | Pallor (HP:0000980) | 2.15883508 |
| 57 | Methylmalonic aciduria (HP:0012120) | 2.14853789 |
| 58 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.14760020 |
| 59 | Leukodystrophy (HP:0002415) | 2.12063525 |
| 60 | Increased serum pyruvate (HP:0003542) | 2.08817480 |
| 61 | Septo-optic dysplasia (HP:0100842) | 2.07313586 |
| 62 | Cerebral palsy (HP:0100021) | 2.00946319 |
| 63 | Congenital stationary night blindness (HP:0007642) | 2.00786893 |
| 64 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.00040273 |
| 65 | Testicular atrophy (HP:0000029) | 1.97704291 |
| 66 | Panhypogammaglobulinemia (HP:0003139) | 1.96533179 |
| 67 | Abnormality of renal resorption (HP:0011038) | 1.90819628 |
| 68 | Tubulointerstitial nephritis (HP:0001970) | 1.86961056 |
| 69 | Abnormality of the anterior horn cell (HP:0006802) | 1.86810036 |
| 70 | Degeneration of anterior horn cells (HP:0002398) | 1.86810036 |
| 71 | Medial flaring of the eyebrow (HP:0010747) | 1.86804930 |
| 72 | Sclerocornea (HP:0000647) | 1.85837966 |
| 73 | Thrombocytosis (HP:0001894) | 1.85257938 |
| 74 | Rhabdomyolysis (HP:0003201) | 1.84087330 |
| 75 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.83507247 |
| 76 | Neutropenia (HP:0001875) | 1.82718908 |
| 77 | Abnormality of glycolysis (HP:0004366) | 1.81207798 |
| 78 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.80358374 |
| 79 | IgG deficiency (HP:0004315) | 1.79226958 |
| 80 | B lymphocytopenia (HP:0010976) | 1.78493506 |
| 81 | Nephrogenic diabetes insipidus (HP:0009806) | 1.78458993 |
| 82 | Increased IgM level (HP:0003496) | 1.78382209 |
| 83 | Hyperglycinuria (HP:0003108) | 1.78119861 |
| 84 | Rib fusion (HP:0000902) | 1.76533575 |
| 85 | Reduced antithrombin III activity (HP:0001976) | 1.76227842 |
| 86 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.75864083 |
| 87 | Gliosis (HP:0002171) | 1.75386970 |
| 88 | Abnormality of B cell number (HP:0010975) | 1.73905561 |
| 89 | Opisthotonus (HP:0002179) | 1.72693952 |
| 90 | Abnormality of glycine metabolism (HP:0010895) | 1.71770392 |
| 91 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.71770392 |
| 92 | Severe combined immunodeficiency (HP:0004430) | 1.71183063 |
| 93 | Multiple enchondromatosis (HP:0005701) | 1.70340989 |
| 94 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.69184264 |
| 95 | Flat capital femoral epiphysis (HP:0003370) | 1.68296546 |
| 96 | Hyperthyroidism (HP:0000836) | 1.68081901 |
| 97 | Abnormality of serum amino acid levels (HP:0003112) | 1.68014666 |
| 98 | Methylmalonic acidemia (HP:0002912) | 1.66111262 |
| 99 | Hypoplasia of the uterus (HP:0000013) | 1.65619325 |
| 100 | Congenital primary aphakia (HP:0007707) | 1.65468434 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.56093945 |
| 2 | BCKDK | 4.14069795 |
| 3 | TESK2 | 3.95731612 |
| 4 | NME2 | 3.70922084 |
| 5 | MAP4K2 | 2.87474340 |
| 6 | STK16 | 2.81995679 |
| 7 | KDR | 2.72390124 |
| 8 | PIM2 | 2.48449058 |
| 9 | SRPK1 | 2.31698139 |
| 10 | ZAK | 2.22804477 |
| 11 | TESK1 | 2.15916856 |
| 12 | CDC7 | 2.02285483 |
| 13 | VRK1 | 1.98480057 |
| 14 | BUB1 | 1.88356815 |
| 15 | TLK1 | 1.80885250 |
| 16 | LIMK1 | 1.68764719 |
| 17 | TAOK3 | 1.67767912 |
| 18 | ARAF | 1.67123307 |
| 19 | SCYL2 | 1.60302879 |
| 20 | NUAK1 | 1.54111547 |
| 21 | CSNK1G3 | 1.51234539 |
| 22 | MAP3K11 | 1.50257123 |
| 23 | PINK1 | 1.43053460 |
| 24 | MAP2K7 | 1.35909144 |
| 25 | CDK19 | 1.32983867 |
| 26 | DYRK2 | 1.24652623 |
| 27 | ABL2 | 1.21632606 |
| 28 | RPS6KA4 | 1.17485848 |
| 29 | DAPK1 | 1.15561825 |
| 30 | CSNK1G2 | 1.14492016 |
| 31 | MAP4K1 | 1.13239802 |
| 32 | CSNK1A1L | 1.13123482 |
| 33 | MAP3K12 | 1.12814428 |
| 34 | CCNB1 | 1.08346785 |
| 35 | PDK2 | 1.07987024 |
| 36 | ATR | 1.06545706 |
| 37 | PBK | 1.05968133 |
| 38 | LRRK2 | 1.05760091 |
| 39 | EIF2AK1 | 1.02684994 |
| 40 | RPS6KA5 | 1.01691544 |
| 41 | AURKA | 1.00910816 |
| 42 | CSNK1G1 | 0.97147317 |
| 43 | TNK2 | 0.91523632 |
| 44 | FLT3 | 0.89565239 |
| 45 | NME1 | 0.83907764 |
| 46 | CDK8 | 0.78929353 |
| 47 | PLK1 | 0.78909738 |
| 48 | DAPK3 | 0.77615263 |
| 49 | AURKB | 0.76335032 |
| 50 | GRK6 | 0.74823525 |
| 51 | CHEK2 | 0.74813808 |
| 52 | PIM1 | 0.73319625 |
| 53 | PLK4 | 0.72894458 |
| 54 | CSNK2A2 | 0.71961344 |
| 55 | ADRBK2 | 0.70708081 |
| 56 | BMPR1B | 0.70041141 |
| 57 | CSF1R | 0.69284391 |
| 58 | WNK4 | 0.68616367 |
| 59 | TXK | 0.68587133 |
| 60 | GRK1 | 0.67769765 |
| 61 | TEC | 0.66333909 |
| 62 | NEK1 | 0.66115756 |
| 63 | CSNK2A1 | 0.63147213 |
| 64 | PRKCQ | 0.60697051 |
| 65 | MAPKAPK3 | 0.60115253 |
| 66 | IKBKB | 0.59434066 |
| 67 | EPHA4 | 0.59218267 |
| 68 | ERN1 | 0.58662616 |
| 69 | RPS6KB2 | 0.52887901 |
| 70 | CDK7 | 0.51725881 |
| 71 | TBK1 | 0.50911053 |
| 72 | KIT | 0.49885681 |
| 73 | MST4 | 0.49611181 |
| 74 | PRKCI | 0.48771948 |
| 75 | RAF1 | 0.48764615 |
| 76 | BCR | 0.47932494 |
| 77 | BTK | 0.47769854 |
| 78 | PLK3 | 0.46304762 |
| 79 | CSNK1A1 | 0.45926630 |
| 80 | TRIM28 | 0.45585779 |
| 81 | TAF1 | 0.44171388 |
| 82 | MAP3K5 | 0.41863545 |
| 83 | PAK1 | 0.39612091 |
| 84 | CHEK1 | 0.37945484 |
| 85 | DYRK3 | 0.37117111 |
| 86 | GRK5 | 0.35661568 |
| 87 | DYRK1B | 0.34485182 |
| 88 | TIE1 | 0.34240036 |
| 89 | SYK | 0.33864755 |
| 90 | CDK14 | 0.33249960 |
| 91 | MAPK13 | 0.33133820 |
| 92 | AKT2 | 0.33114107 |
| 93 | CAMK1 | 0.32982118 |
| 94 | LYN | 0.32093030 |
| 95 | ITK | 0.31562490 |
| 96 | MAP2K2 | 0.31533663 |
| 97 | BRAF | 0.31345844 |
| 98 | LCK | 0.30965052 |
| 99 | TAOK2 | 0.29523413 |
| 100 | PRKCD | 0.28834919 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.32813159 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.18870538 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.92754546 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.46920889 |
| 5 | DNA replication_Homo sapiens_hsa03030 | 3.12056282 |
| 6 | Base excision repair_Homo sapiens_hsa03410 | 2.92171689 |
| 7 | Sulfur relay system_Homo sapiens_hsa04122 | 2.82280827 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.64386399 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.40017161 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 2.26537202 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 2.22810162 |
| 12 | Mismatch repair_Homo sapiens_hsa03430 | 2.18598534 |
| 13 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.08855443 |
| 14 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.04741215 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.01878245 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 2.00201863 |
| 17 | Protein export_Homo sapiens_hsa03060 | 1.96891834 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.94241799 |
| 19 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.88500735 |
| 20 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.74654243 |
| 21 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.57448600 |
| 22 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.51608060 |
| 23 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.50926069 |
| 24 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.47137502 |
| 25 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.38488432 |
| 26 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.37958705 |
| 27 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.31805246 |
| 28 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.30945135 |
| 29 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.30210346 |
| 30 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.26543638 |
| 31 | Asthma_Homo sapiens_hsa05310 | 1.26532207 |
| 32 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.26155044 |
| 33 | RNA degradation_Homo sapiens_hsa03018 | 1.23789668 |
| 34 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.23183012 |
| 35 | RNA transport_Homo sapiens_hsa03013 | 1.16792326 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.12591255 |
| 37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.10473947 |
| 38 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.09427664 |
| 39 | Peroxisome_Homo sapiens_hsa04146 | 1.06118278 |
| 40 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.00347726 |
| 41 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.99269450 |
| 42 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.96083450 |
| 43 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.94561782 |
| 44 | Basal transcription factors_Homo sapiens_hsa03022 | 0.92628964 |
| 45 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.90550479 |
| 46 | Allograft rejection_Homo sapiens_hsa05330 | 0.90275608 |
| 47 | Metabolic pathways_Homo sapiens_hsa01100 | 0.88860364 |
| 48 | Carbon metabolism_Homo sapiens_hsa01200 | 0.88209391 |
| 49 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.85737654 |
| 50 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.85458178 |
| 51 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.83635444 |
| 52 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.80828046 |
| 53 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.80472678 |
| 54 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.80295769 |
| 55 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.79720757 |
| 56 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.74496453 |
| 57 | Phototransduction_Homo sapiens_hsa04744 | 0.71744169 |
| 58 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.71613685 |
| 59 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.70837456 |
| 60 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.68821416 |
| 61 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.66749224 |
| 62 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.65141972 |
| 63 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.59493921 |
| 64 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.57149227 |
| 65 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.56133882 |
| 66 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.55730655 |
| 67 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.55010455 |
| 68 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.54438158 |
| 69 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.50307467 |
| 70 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.47198722 |
| 71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.46313969 |
| 72 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.45829155 |
| 73 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.45092916 |
| 74 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.43151493 |
| 75 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.42586029 |
| 76 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.40362841 |
| 77 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.37394625 |
| 78 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.36346262 |
| 79 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.33807232 |
| 80 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.32730477 |
| 81 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.32021975 |
| 82 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.30766767 |
| 83 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.30539256 |
| 84 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.30451601 |
| 85 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.27588590 |
| 86 | Alcoholism_Homo sapiens_hsa05034 | 0.27141617 |
| 87 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.26474621 |
| 88 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.25081995 |
| 89 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.24391311 |
| 90 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.23815119 |
| 91 | Cell cycle_Homo sapiens_hsa04110 | 0.22852427 |
| 92 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.22784925 |
| 93 | Viral myocarditis_Homo sapiens_hsa05416 | 0.22643206 |
| 94 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.22039368 |
| 95 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.21893404 |
| 96 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.21491873 |
| 97 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.18147958 |
| 98 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.17107480 |
| 99 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.16881150 |
| 100 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.16151229 |

