NCCRP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1polyol transport (GO:0015791)9.89457974
2renal absorption (GO:0070293)8.30436799
3response to mercury ion (GO:0046689)8.23962482
4establishment of skin barrier (GO:0061436)8.19608543
5hair cycle (GO:0042633)8.12317221
6molting cycle (GO:0042303)8.12317221
7keratinocyte proliferation (GO:0043616)8.09960083
8excretion (GO:0007588)7.97559846
9desmosome organization (GO:0002934)7.82930308
10regulation of water loss via skin (GO:0033561)7.42302886
11collecting duct development (GO:0072044)7.24669360
12one-carbon compound transport (GO:0019755)7.18654760
13actin filament depolymerization (GO:0030042)7.01798890
14lipoxygenase pathway (GO:0019372)6.29600352
15linoleic acid metabolic process (GO:0043651)5.91215191
16intermediate filament organization (GO:0045109)5.88013646
17gap junction assembly (GO:0016264)5.87102525
18multicellular organismal water homeostasis (GO:0050891)5.79066714
19phosphatidylinositol acyl-chain remodeling (GO:0036149)5.73752940
20metanephric tubule development (GO:0072170)5.56991109
21metanephric nephron tubule development (GO:0072234)5.56991109
22phosphatidylserine acyl-chain remodeling (GO:0036150)5.53006226
23metanephric nephron epithelium development (GO:0072243)5.25207303
24cell volume homeostasis (GO:0006884)5.17917592
25detection of bacterium (GO:0016045)5.12382515
26cardiovascular system development (GO:0072358)5.05983981
27response to water (GO:0009415)5.03878779
28peptide cross-linking (GO:0018149)4.99006153
29bundle of His cell to Purkinje myocyte communication (GO:0086069)4.95982118
30water homeostasis (GO:0030104)4.89768186
31establishment of planar polarity (GO:0001736)4.88792173
32establishment of tissue polarity (GO:0007164)4.88792173
33phosphatidylethanolamine acyl-chain remodeling (GO:0036152)4.72218106
34keratinocyte differentiation (GO:0030216)4.68658717
35metanephric epithelium development (GO:0072207)4.67655181
36detection of other organism (GO:0098543)4.59344776
37regulation of natural killer cell differentiation (GO:0032823)4.57223258
38lysine catabolic process (GO:0006554)4.45463719
39lysine metabolic process (GO:0006553)4.45463719
40phosphatidylglycerol acyl-chain remodeling (GO:0036148)4.32904788
41intestinal epithelial cell development (GO:0060576)4.26558768
42negative regulation of interferon-gamma production (GO:0032689)4.24469415
43phosphatidylcholine acyl-chain remodeling (GO:0036151)4.15260068
44cell-substrate junction assembly (GO:0007044)4.14272421
45lateral sprouting from an epithelium (GO:0060601)4.11549800
46ectoderm development (GO:0007398)4.10308473
47regulation of Wnt signaling pathway involved in heart development (GO:0003307)4.07850028
48regulation of hippo signaling (GO:0035330)4.04392748
49epidermal cell differentiation (GO:0009913)3.83815172
50polarized epithelial cell differentiation (GO:0030859)3.82474625
51nephron tubule development (GO:0072080)3.74662492
52hyperosmotic response (GO:0006972)3.74455478
53epithelium development (GO:0060429)3.71388451
54skin morphogenesis (GO:0043589)3.70920199
55eyelid development in camera-type eye (GO:0061029)3.66005587
56epidermis development (GO:0008544)3.65259270
57skin development (GO:0043588)3.61285803
58water transport (GO:0006833)3.60172127
59regulation of neuron projection regeneration (GO:0070570)3.60156662
60regulation of axon regeneration (GO:0048679)3.60156662
61epithelial cell-cell adhesion (GO:0090136)3.59306500
62positive regulation of G-protein coupled receptor protein signaling pathway (GO:0045745)3.58910253
63negative regulation of interleukin-17 production (GO:0032700)3.57815340
64response to copper ion (GO:0046688)3.49479721
65cytoskeletal anchoring at plasma membrane (GO:0007016)3.42215455
66long-chain fatty acid biosynthetic process (GO:0042759)3.41721242
67intermediate filament cytoskeleton organization (GO:0045104)3.41398502
68renal system development (GO:0072001)3.35945392
69interferon-gamma secretion (GO:0072643)3.33842344
70hair follicle morphogenesis (GO:0031069)3.33353264
71fluid transport (GO:0042044)3.33122943
72aspartate family amino acid catabolic process (GO:0009068)3.27943335
73intermediate filament-based process (GO:0045103)3.26423240
74hair cell differentiation (GO:0035315)3.24150795
75renal tubule development (GO:0061326)3.21620506
76phosphatidylserine metabolic process (GO:0006658)3.21282645
77renal system process (GO:0003014)3.21191750
78regulation of keratinocyte proliferation (GO:0010837)3.20663213
79pattern specification involved in kidney development (GO:0061004)3.18181534
80phospholipid catabolic process (GO:0009395)3.18039273
81negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.17172901
82positive regulation of catenin import into nucleus (GO:0035413)3.14966086
832-oxoglutarate metabolic process (GO:0006103)3.12839179
84ceramide biosynthetic process (GO:0046513)3.12042473
85regulation of keratinocyte differentiation (GO:0045616)3.11445054
86response to salt stress (GO:0009651)3.11425616
87regulation of ruffle assembly (GO:1900027)3.10387677
88defense response to fungus (GO:0050832)3.07493767
89negative regulation of keratinocyte proliferation (GO:0010839)3.07322651
90nephron epithelium development (GO:0072009)3.05340511
91keratinocyte development (GO:0003334)3.05307314
92sodium ion export (GO:0071436)3.00324059
93regulation of natural killer cell activation (GO:0032814)2.96175182
94chemical homeostasis within a tissue (GO:0048875)2.90068269
95regulation of T cell chemotaxis (GO:0010819)2.89268391
96positive regulation of T cell chemotaxis (GO:0010820)2.89268391
97epithelial cell maturation (GO:0002070)2.84878114
98positive regulation of monocyte chemotaxis (GO:0090026)2.83569771
99magnesium ion transport (GO:0015693)2.79267695
100epithelial cell differentiation (GO:0030855)2.77927233
101positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.75211075
102tricarboxylic acid metabolic process (GO:0072350)2.73652738
103positive regulation of hair cycle (GO:0042635)2.72606721
104positive regulation of hair follicle development (GO:0051798)2.72606721
105mesodermal cell differentiation (GO:0048333)2.72079157
106cellular response to osmotic stress (GO:0071470)2.71373841
107renal filtration (GO:0097205)2.69026403
108hyperosmotic salinity response (GO:0042538)2.68361873
109atrial cardiac muscle cell action potential (GO:0086014)2.67173897
110hypotonic response (GO:0006971)2.67059615
111response to lithium ion (GO:0010226)2.66066021
112sympathetic nervous system development (GO:0048485)2.65425055
113adhesion of symbiont to host cell (GO:0044650)2.62845626
114virion attachment to host cell (GO:0019062)2.62845626
115cellular hyperosmotic response (GO:0071474)2.62472770
116regulation of hair follicle development (GO:0051797)2.62311086
117drug transmembrane transport (GO:0006855)2.62309038
1184-hydroxyproline metabolic process (GO:0019471)2.62293506
119surfactant homeostasis (GO:0043129)2.61805464
120alditol phosphate metabolic process (GO:0052646)2.60772068
121apoptotic cell clearance (GO:0043277)2.60498328
122apical protein localization (GO:0045176)2.60405882
123positive regulation of epidermis development (GO:0045684)2.60405588
124ventricular cardiac muscle cell action potential (GO:0086005)2.59821782
125protein K11-linked deubiquitination (GO:0035871)2.56142425
126sequestering of metal ion (GO:0051238)2.54822348
127proximal/distal pattern formation (GO:0009954)2.54432370
128glomerular filtration (GO:0003094)2.52542383
129regulation of heart rate by cardiac conduction (GO:0086091)2.51784068
130cardiac muscle cell action potential involved in contraction (GO:0086002)2.50084254
131phosphate ion transport (GO:0006817)2.50049230
132positive regulation of p38MAPK cascade (GO:1900745)2.49540700
133transepithelial transport (GO:0070633)2.47603349
134regulation of epidermis development (GO:0045682)2.47320042
135regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.47318682
136cardiac muscle cell action potential (GO:0086001)2.46939622
137urate metabolic process (GO:0046415)2.46692985
138atrioventricular valve morphogenesis (GO:0003181)2.46442347
139cellular potassium ion homeostasis (GO:0030007)2.45560435
140glyoxylate metabolic process (GO:0046487)2.44767166
141molting cycle process (GO:0022404)2.44088574
142hair cycle process (GO:0022405)2.44088574
143regulation of cell fate specification (GO:0042659)2.43003778
144regulation of potassium ion transmembrane transporter activity (GO:1901016)2.41693632
145cysteine metabolic process (GO:0006534)2.41169322
146early endosome to late endosome transport (GO:0045022)2.40370936
147quaternary ammonium group transport (GO:0015697)2.38848424
148sphingolipid biosynthetic process (GO:0030148)2.38565814
149fatty acid elongation (GO:0030497)2.38140732
150negative regulation of cell fate specification (GO:0009996)2.36809226
151positive regulation of epidermal cell differentiation (GO:0045606)2.35512330
152phosphatidylglycerol metabolic process (GO:0046471)2.34772570
153organic cation transport (GO:0015695)2.34411974
154erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.33540590
155L-phenylalanine metabolic process (GO:0006558)2.33540590
156protein localization to endosome (GO:0036010)2.33117107
157regulation of cholesterol homeostasis (GO:2000188)2.32982331
158parturition (GO:0007567)2.32365319
159skeletal muscle tissue regeneration (GO:0043403)2.32074459
160amino-acid betaine transport (GO:0015838)2.32005523
161cornea development in camera-type eye (GO:0061303)2.30504878
162epithelial cell differentiation involved in prostate gland development (GO:0060742)2.29750018
163regulation of tight junction assembly (GO:2000810)2.27648160
164detection of external biotic stimulus (GO:0098581)2.25887893
165negative regulation of epidermal cell differentiation (GO:0045605)2.25338442
166endothelium development (GO:0003158)2.25108787
167smooth muscle tissue development (GO:0048745)2.24684185
168genitalia morphogenesis (GO:0035112)2.23227599
169regulation of glomerular filtration (GO:0003093)2.22614402
170regulation of protein localization to cell surface (GO:2000008)2.19789741
171negative regulation of cell aging (GO:0090344)2.16956591
172keratinization (GO:0031424)10.1396445
173hemidesmosome assembly (GO:0031581)10.0923234

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF263_19887448_ChIP-Seq_K562_Human3.84174824
2RARG_19884340_ChIP-ChIP_MEFs_Mouse2.91678500
3TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.81259471
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.76112487
5VDR_22108803_ChIP-Seq_LS180_Human2.45538352
6ESR1_21235772_ChIP-Seq_MCF-7_Human2.41456739
7ESR2_21235772_ChIP-Seq_MCF-7_Human2.40059156
8SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.38769071
9TRIM28_21343339_ChIP-Seq_HEK293_Human2.22750282
10ZNF217_24962896_ChIP-Seq_MCF-7_Human2.20554256
11P63_26484246_Chip-Seq_KERATINOCYTES_Human2.12772560
12TP63_23658742_ChIP-Seq_EP156T_Human2.09035130
13HIF1A_21447827_ChIP-Seq_MCF-7_Human2.00517018
14TP63_17297297_ChIP-ChIP_HaCaT_Human12.7947850
15ZFP57_27257070_Chip-Seq_ESCs_Mouse1.98298394
16* RACK7_27058665_Chip-Seq_MCF-7_Human1.97974690
17ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.85474498
18FOXO3_23340844_ChIP-Seq_DLD1_Human1.82295319
19SOX9_24532713_ChIP-Seq_HFSC_Mouse1.79777221
20CLOCK_20551151_ChIP-Seq_293T_Human1.74942346
21GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.74596521
22* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.67736041
23ATF3_27146783_Chip-Seq_COLON_Human1.67265420
24KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.67151250
25CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.65961637
26ELK3_25401928_ChIP-Seq_HUVEC_Human1.64983584
27POU3F2_20337985_ChIP-ChIP_501MEL_Human1.64143381
28TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.63136050
29LXR_22292898_ChIP-Seq_THP-1_Human1.62035127
30NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.61911827
31GATA6_21074721_ChIP-Seq_CACO-2_Human1.60970324
32FOXM1_26456572_ChIP-Seq_MCF-7_Human1.60208350
33AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.58960764
34PIAS1_25552417_ChIP-Seq_VCAP_Human1.58587738
35KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.56063591
36EGR1_19032775_ChIP-ChIP_M12_Human1.53709157
37ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.53184760
38ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.50695928
39SRY_22984422_ChIP-ChIP_TESTIS_Rat1.50312266
40CJUN_26792858_Chip-Seq_BT549_Human1.49185084
41CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.46731390
42AR_25329375_ChIP-Seq_VCAP_Human1.44992956
43FUS_26573619_Chip-Seq_HEK293_Human1.43976405
44* AHR_22903824_ChIP-Seq_MCF-7_Human1.43144510
45P300_27058665_Chip-Seq_ZR-75-30cells_Human1.42652506
46SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.41924145
47SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.41924145
48TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.40858937
49NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.38276775
50UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.38179027
51ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.36997739
52ERG_20517297_ChIP-Seq_VCAP_Human1.36639728
53TCF4_22108803_ChIP-Seq_LS180_Human1.36014110
54KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.35983309
55AR_21572438_ChIP-Seq_LNCaP_Human1.35053519
56SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.34882531
57RXR_22158963_ChIP-Seq_LIVER_Mouse1.34433041
58PPARA_22158963_ChIP-Seq_LIVER_Mouse1.33803251
59SMAD4_21799915_ChIP-Seq_A2780_Human1.33640048
60ZFP281_18757296_ChIP-ChIP_E14_Mouse1.32045650
61STAT6_21828071_ChIP-Seq_BEAS2B_Human1.31681531
62DNAJC2_21179169_ChIP-ChIP_NT2_Human1.31222153
63KDM2B_26808549_Chip-Seq_SUP-B15_Human1.30702184
64BCAT_22108803_ChIP-Seq_LS180_Human1.30618131
65* CTCF_27219007_Chip-Seq_Bcells_Human1.29746041
66KLF5_25053715_ChIP-Seq_YYC3_Human1.29653029
67THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.29610746
68P300_19829295_ChIP-Seq_ESCs_Human1.28844563
69TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.28726303
70NRF2_20460467_ChIP-Seq_MEFs_Mouse1.27983576
71NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.27983576
72GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.27557378
73* ARNT_22903824_ChIP-Seq_MCF-7_Human1.24949648
74CDX2_22108803_ChIP-Seq_LS180_Human1.24055025
75CDX2_20551321_ChIP-Seq_CACO-2_Human1.23529798
76CDX2_19796622_ChIP-Seq_MESCs_Mouse1.22876101
77TP53_18474530_ChIP-ChIP_U2OS_Human1.22190942
78TP63_22573176_ChIP-Seq_HFKS_Human1.21276138
79RBPJ_21746931_ChIP-Seq_IB4_Human1.21215394
80TAF15_26573619_Chip-Seq_HEK293_Human1.20875077
81NR3C1_21868756_ChIP-Seq_MCF10A_Human1.20777778
82AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.20306342
83WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.18792769
84P68_20966046_ChIP-Seq_HELA_Human1.18684918
85TCF4_18268006_ChIP-ChIP_LS174T_Human1.18545879
86GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.18229136
87FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.17589922
88KDM2B_26808549_Chip-Seq_DND41_Human1.17579862
89STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.17376243
90* RUNX1_27514584_Chip-Seq_MCF-7_Human1.17057324
91GATA6_25053715_ChIP-Seq_YYC3_Human1.16953681
92GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16443328
93SA1_27219007_Chip-Seq_ERYTHROID_Human1.16126330
94ZNF274_21170338_ChIP-Seq_K562_Hela1.16052496
95RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.15103754
96CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.14904892
97NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.14500085
98SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.14276288
99SOX2_20726797_ChIP-Seq_SW620_Human1.14038825
100KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.12278374
101HTT_18923047_ChIP-ChIP_STHdh_Human1.12274163
102* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.11791110
103SOX2_27498859_Chip-Seq_STOMACH_Mouse1.11749591
104ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.10970871
105PCGF2_27294783_Chip-Seq_NPCs_Mouse1.09925083
106TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.09859060
107CTBP2_25329375_ChIP-Seq_LNCAP_Human1.08938672
108POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08313428
109TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08313428
110GBX2_23144817_ChIP-Seq_PC3_Human1.07880323
111ERG_21242973_ChIP-ChIP_JURKAT_Human1.06883236
112CREB1_26743006_Chip-Seq_LNCaP_Human1.06456907
113UBF1/2_26484160_Chip-Seq_HMECs_Human1.06446479
114MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.06431823
115NCOR_22424771_ChIP-Seq_293T_Human1.06196075
116MYC_22102868_ChIP-Seq_BL_Human1.05939195
117SMAD3_21741376_ChIP-Seq_EPCs_Human1.05791443
118P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.05533783
119KDM2B_26808549_Chip-Seq_K562_Human1.04656422
120EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.03643921
121UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.03447943
122FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.01955451
123TP53_16413492_ChIP-PET_HCT116_Human1.01796549
124BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.01677619
125NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.01596316
126SMAD3_21741376_ChIP-Seq_HESCs_Human1.00705496
127STAT3_1855785_ChIP-Seq_MESCs_Mouse0.99984935
128FOXA1_21572438_ChIP-Seq_LNCaP_Human0.99589291
129PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.99062016
130SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.98754900
131TCF7_22412390_ChIP-Seq_EML_Mouse0.98546274
132RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.98076386
133RXR_22108803_ChIP-Seq_LS180_Human0.97875386
134FLI1_27457419_Chip-Seq_LIVER_Mouse0.97606007
135STAT3_23295773_ChIP-Seq_U87_Human0.97361735
136HNFA_21074721_ChIP-Seq_CACO-2_Human0.97177663
137TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.96701944
138KDM2B_26808549_Chip-Seq_JURKAT_Human0.96469695
139NANOG_18692474_ChIP-Seq_MEFs_Mouse0.96313407
140CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.96126411
141CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.95991386
142GATA3_21878914_ChIP-Seq_MCF-7_Human0.95751911
143P53_22127205_ChIP-Seq_FIBROBLAST_Human0.95257919
144CTBP1_25329375_ChIP-Seq_LNCAP_Human0.95247199
145E2F1_20622854_ChIP-Seq_HELA_Human0.94913468
146EZH2_27294783_Chip-Seq_NPCs_Mouse0.94910717
147GATA4_25053715_ChIP-Seq_YYC3_Human0.94748314
148ELF1_20517297_ChIP-Seq_JURKAT_Human0.94665397
149TP53_22127205_ChIP-Seq_IMR90_Human0.93963246
150FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.93524884
151PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.93495311
152POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.93048936
153TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.92992660
154SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.92707104
155ETV1_20927104_ChIP-Seq_GIST48_Human0.92428671
156AUTS2_25519132_ChIP-Seq_293T-REX_Human0.91709835
157FOXA1_25552417_ChIP-Seq_VCAP_Human0.91493414
158TCF4_23295773_ChIP-Seq_U87_Human0.91476473
159OCT1_27270436_Chip-Seq_PROSTATE_Human0.90200444
160FOXH1_21741376_ChIP-Seq_EPCs_Human0.90095134
161GATA3_24758297_ChIP-Seq_MCF-7_Human0.89636552
162* P53_21459846_ChIP-Seq_SAOS-2_Human0.89525810
163TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.89376797
164BCOR_27268052_Chip-Seq_Bcells_Human0.88838796
165NANOG_19829295_ChIP-Seq_ESCs_Human0.88364094
166ESR1_20079471_ChIP-ChIP_T-47D_Human0.88113405
167ZFP281_27345836_Chip-Seq_ESCs_Mouse0.87941014
168GATA2_21666600_ChIP-Seq_HMVEC_Human0.87928343
169PPAR_26484153_Chip-Seq_NCI-H1993_Human0.87739913
170* SMC4_20622854_ChIP-Seq_HELA_Human0.87312934
171HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.87074413
172TP53_20018659_ChIP-ChIP_R1E_Mouse0.86752276
173TCF3_18692474_ChIP-Seq_MEFs_Mouse0.86300291
174ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.85886753
175EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.85101215
176LXR_22158963_ChIP-Seq_LIVER_Mouse0.83480081
177TBX20_22080862_ChIP-Seq_HEART_Mouse0.83093400
178TBX20_22328084_ChIP-Seq_HEART_Mouse0.83093400
179EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.83054158

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004043_abnormal_pH_regulation5.76224105
2MP0002796_impaired_skin_barrier5.75269744
3MP0000579_abnormal_nail_morphology5.12794020
4MP0010234_abnormal_vibrissa_follicle4.82212031
5MP0003195_calcinosis4.34812270
6MP0005275_abnormal_skin_tensile4.01350091
7MP0005501_abnormal_skin_physiology3.92010343
8MP0000467_abnormal_esophagus_morphology3.66287239
9MP0001756_abnormal_urination3.59823638
10MP0003705_abnormal_hypodermis_morpholog2.79967965
11MP0000762_abnormal_tongue_morphology2.71257941
12MP0003941_abnormal_skin_development2.68627158
13MP0004381_abnormal_hair_follicle2.53953649
14MP0001216_abnormal_epidermal_layer2.29385376
15MP0003566_abnormal_cell_adhesion2.21577524
16MP0010678_abnormal_skin_adnexa2.18887229
17MP0002234_abnormal_pharynx_morphology2.17252668
18MP0001188_hyperpigmentation2.14530429
19MP0003453_abnormal_keratinocyte_physiol2.13351062
20MP0009379_abnormal_foot_pigmentation2.03886313
21MP0009643_abnormal_urine_homeostasis2.00193900
22MP0010771_integument_phenotype1.98925036
23MP0002060_abnormal_skin_morphology1.98744317
24MP0000538_abnormal_urinary_bladder1.96842134
25MP0001849_ear_inflammation1.96577950
26MP0002095_abnormal_skin_pigmentation1.95150073
27MP0000566_synostosis1.93956752
28MP0002098_abnormal_vibrissa_morphology1.87536868
29MP0003315_abnormal_perineum_morphology1.82535589
30MP0000383_abnormal_hair_follicle1.82343361
31MP0008961_abnormal_basal_metabolism1.80940822
32MP0009053_abnormal_anal_canal1.78273889
33MP0004885_abnormal_endolymph1.77219989
34MP0004782_abnormal_surfactant_physiolog1.77083324
35MP0001765_abnormal_ion_homeostasis1.75423939
36MP0000377_abnormal_hair_follicle1.64601019
37MP0002136_abnormal_kidney_physiology1.63049425
38MP0005451_abnormal_body_composition1.56488010
39MP0000534_abnormal_ureter_morphology1.55368628
40MP0010352_gastrointestinal_tract_polyps1.50676556
41MP0003011_delayed_dark_adaptation1.49965587
42MP0005332_abnormal_amino_acid1.48174695
43MP0002282_abnormal_trachea_morphology1.46655398
44MP0004185_abnormal_adipocyte_glucose1.44459344
45MP0000647_abnormal_sebaceous_gland1.43229957
46MP0001191_abnormal_skin_condition1.33569526
47MP0004858_abnormal_nervous_system1.33450566
48MP0005360_urolithiasis1.32862322
49MP0000465_gastrointestinal_hemorrhage1.28678886
50MP0008789_abnormal_olfactory_epithelium1.27407579
51MP0009931_abnormal_skin_appearance1.26611151
52MP0002168_other_aberrant_phenotype1.25843009
53MP0004233_abnormal_muscle_weight1.21064169
54MP0004947_skin_inflammation1.16490011
55MP0000427_abnormal_hair_cycle1.11586718
56MP0003191_abnormal_cellular_cholesterol1.10809977
57MP0005409_darkened_coat_color1.08986771
58MP0002089_abnormal_postnatal_growth/wei1.08685686
59MP0005666_abnormal_adipose_tissue1.07338952
60MP0000516_abnormal_urinary_system1.05855472
61MP0005367_renal/urinary_system_phenotyp1.05855472
62MP0000015_abnormal_ear_pigmentation1.04257677
63MP0000372_irregular_coat_pigmentation1.03785225
64MP0005174_abnormal_tail_pigmentation1.02214743
65MP0002254_reproductive_system_inflammat0.99515915
66MP0005636_abnormal_mineral_homeostasis0.99251205
67MP0002653_abnormal_ependyma_morphology0.99178517
68MP0005248_abnormal_Harderian_gland0.99142614
69MP0005394_taste/olfaction_phenotype0.98257081
70MP0005499_abnormal_olfactory_system0.98257081
71MP0004019_abnormal_vitamin_homeostasis0.97708456
72MP0000367_abnormal_coat/_hair0.95883434
73MP0004272_abnormal_basement_membrane0.91236640
74MP0002138_abnormal_hepatobiliary_system0.88360961
75MP0004264_abnormal_extraembryonic_tissu0.87141453
76MP0009780_abnormal_chondrocyte_physiolo0.86523872
77MP0002877_abnormal_melanocyte_morpholog0.85316665
78MP0003045_fibrosis0.84616730
79MP0001851_eye_inflammation0.84590184
80MP0010030_abnormal_orbit_morphology0.83791236
81MP0000569_abnormal_digit_pigmentation0.83185253
82MP0009384_cardiac_valve_regurgitation0.79678197
83MP0005076_abnormal_cell_differentiation0.77487713
84MP0005075_abnormal_melanosome_morpholog0.74479785
85MP0001984_abnormal_olfaction0.72355466
86MP0003252_abnormal_bile_duct0.69002736
87MP0003950_abnormal_plasma_membrane0.67933973
88MP0001784_abnormal_fluid_regulation0.67809778
89MP0001485_abnormal_pinna_reflex0.61896967
90MP0005375_adipose_tissue_phenotype0.61107477
91MP0005023_abnormal_wound_healing0.57902971
92MP0002139_abnormal_hepatobiliary_system0.56808281
93MP0002135_abnormal_kidney_morphology0.56302668
94MP0001958_emphysema0.56272811
95MP0001243_abnormal_dermal_layer0.55627240
96MP0003300_gastrointestinal_ulcer0.54716708
97MP0003755_abnormal_palate_morphology0.52828437
98MP0000371_diluted_coat_color0.52792324
99MP0001270_distended_abdomen0.52635635
100MP0000747_muscle_weakness0.47899595
101MP0005171_absent_coat_pigmentation0.46385954
102MP0003878_abnormal_ear_physiology0.45692422
103MP0005377_hearing/vestibular/ear_phenot0.45692422
104MP0000678_abnormal_parathyroid_gland0.45278880
105MP0003329_amyloid_beta_deposits0.45190083
106MP0000751_myopathy0.44522201
107MP0002177_abnormal_outer_ear0.43948484
108MP0003646_muscle_fatigue0.43478646
109MP0005670_abnormal_white_adipose0.43238675
110MP0002896_abnormal_bone_mineralization0.41676825
111MP0005395_other_phenotype0.41427435
112MP0005503_abnormal_tendon_morphology0.40916027
113MP0003942_abnormal_urinary_system0.39247360
114MP0002009_preneoplasia0.39230468
115MP0006054_spinal_hemorrhage0.39215741
116MP0003959_abnormal_lean_body0.38840201
117MP0002249_abnormal_larynx_morphology0.38803440
118MP0003638_abnormal_response/metabolism_0.38490536
119MP0001324_abnormal_eye_pigmentation0.37784721
120MP0002069_abnormal_eating/drinking_beha0.37663809
121MP0000750_abnormal_muscle_regeneration0.35870454
122MP0002233_abnormal_nose_morphology0.35575304
123MP0008770_decreased_survivor_rate0.35267611
124MP0004742_abnormal_vestibular_system0.35061075
125MP0001340_abnormal_eyelid_morphology0.35057363
126MP0001853_heart_inflammation0.34690873
127MP0009046_muscle_twitch0.34085443
128MP0009333_abnormal_splenocyte_physiolog0.30916907
129MP0001502_abnormal_circadian_rhythm0.30467404
130MP0000627_abnormal_mammary_gland0.29733573
131MP0010386_abnormal_urinary_bladder0.29044321
132MP0008004_abnormal_stomach_pH0.28197444
133MP0001186_pigmentation_phenotype0.26660972
134MP0002876_abnormal_thyroid_physiology0.25252131
135MP0005253_abnormal_eye_physiology0.23973269
136MP0004484_altered_response_of0.23397577
137MP0003567_abnormal_fetal_cardiomyocyte0.22588401
138MP0002111_abnormal_tail_morphology0.22449749
139MP0005408_hypopigmentation0.21742730
140MP0003136_yellow_coat_color0.21723125
141MP0004197_abnormal_fetal_growth/weight/0.20911473
142MP0001542_abnormal_bone_strength0.20442915
143MP0005551_abnormal_eye_electrophysiolog0.20043553
144MP0000470_abnormal_stomach_morphology0.19114005
145MP0004215_abnormal_myocardial_fiber0.18966819
146MP0002075_abnormal_coat/hair_pigmentati0.18676137
147MP0005197_abnormal_uvea_morphology0.18502316
148MP0001286_abnormal_eye_development0.17745026
149MP0005193_abnormal_anterior_eye0.15818214

Predicted human phenotypes

RankGene SetZ-score
1Hypokalemic alkalosis (HP:0001949)9.40475072
2Abnormality of chloride homeostasis (HP:0011422)8.14131399
3Hyperactive renin-angiotensin system (HP:0000841)7.48262758
4Polyuria (HP:0000103)7.18164676
5Increased circulating renin level (HP:0000848)7.11102511
6Renal salt wasting (HP:0000127)7.06798878
7Hyperaldosteronism (HP:0000859)6.76084617
8Abnormal urine output (HP:0012590)6.61542750
9Hypomagnesemia (HP:0002917)6.54513453
10Abnormality of secondary sexual hair (HP:0009888)6.09795206
11Abnormality of the axillary hair (HP:0100134)6.09795206
12Parakeratosis (HP:0001036)5.98644306
13Abnormality of renal excretion (HP:0011036)5.76694955
14Abnormality of magnesium homeostasis (HP:0004921)5.58713656
15Abnormality of nail color (HP:0100643)5.36768969
16Abnormal drinking behavior (HP:0030082)5.33482218
17Polydipsia (HP:0001959)5.33482218
18Tetany (HP:0001281)5.32494173
19Alkalosis (HP:0001948)5.22322427
20Hypokalemia (HP:0002900)4.48733177
21Abnormality of renin-angiotensin system (HP:0000847)4.41170530
22Fragile nails (HP:0001808)4.37147435
23Lip pit (HP:0100267)4.32291674
24Plantar hyperkeratosis (HP:0007556)4.21400757
25Milia (HP:0001056)4.11772588
26Abnormality of sodium homeostasis (HP:0010931)3.99937801
27Gangrene (HP:0100758)3.98539893
28Thick nail (HP:0001805)3.79488913
29Absent eyelashes (HP:0000561)3.78853482
30Gout (HP:0001997)3.73686949
31Adrenal overactivity (HP:0002717)3.68879504
32Pustule (HP:0200039)3.67937709
33Palmoplantar hyperkeratosis (HP:0000972)3.66936556
34Abnormality of potassium homeostasis (HP:0011042)3.54753443
35Absent hair (HP:0002298)3.50612761
36Sparse scalp hair (HP:0002209)3.47846616
37Palmar hyperkeratosis (HP:0010765)3.40961049
38Sparse eyelashes (HP:0000653)3.32347296
39Dehydration (HP:0001944)3.29145689
40Furrowed tongue (HP:0000221)3.27215047
41Hyponatremia (HP:0002902)3.24276783
42Right ventricular cardiomyopathy (HP:0011663)3.17247704
43Neonatal onset (HP:0003623)3.09840498
44Woolly hair (HP:0002224)3.06514111
45Hypoplastic labia majora (HP:0000059)3.06243955
46Alopecia of scalp (HP:0002293)3.03390375
47Abnormality of the salivary glands (HP:0010286)3.01749491
48Abnormal blistering of the skin (HP:0008066)2.90275242
49Hypotrichosis (HP:0001006)2.85964808
50Pili torti (HP:0003777)2.81880593
51Slow-growing hair (HP:0002217)2.80238032
52Abnormality of hair growth rate (HP:0011363)2.80238032
53Abnormality of fatty-acid metabolism (HP:0004359)2.79964439
54Conjunctival hamartoma (HP:0100780)2.77903557
55Oral leukoplakia (HP:0002745)2.76962748
56Abnormality of the labia majora (HP:0012881)2.76677809
57Brittle hair (HP:0002299)2.76550741
58Natal tooth (HP:0000695)2.75139098
59Pruritus (HP:0000989)2.74360252
60Nail dystrophy (HP:0008404)2.70454919
61Atrophic scars (HP:0001075)2.69680443
62Increased IgE level (HP:0003212)2.65500071
63Esophageal atresia (HP:0002032)2.60312530
64Onycholysis (HP:0001806)2.60046986
65Selective tooth agenesis (HP:0001592)2.58474341
66Congenital ichthyosiform erythroderma (HP:0007431)2.55722968
67Hyperuricemia (HP:0002149)2.55149791
68Increased purine levels (HP:0004368)2.55149791
69Advanced eruption of teeth (HP:0006288)2.53428409
70Hypercalciuria (HP:0002150)2.47027955
71Dry hair (HP:0011359)2.41472440
72Aplasia involving bones of the upper limbs (HP:0009823)2.40274737
73Aplasia of the phalanges of the hand (HP:0009802)2.40274737
74Aplasia involving bones of the extremities (HP:0009825)2.40274737
75Abnormality of permanent molar morphology (HP:0011071)2.39773071
76Abnormality of the dental root (HP:0006486)2.39773071
77Taurodontia (HP:0000679)2.39773071
78Ectropion (HP:0000656)2.36828244
79Distal lower limb muscle weakness (HP:0009053)2.27161681
80Oligodontia (HP:0000677)2.26468079
81Lack of skin elasticity (HP:0100679)2.23951551
82Large eyes (HP:0001090)2.23869025
83Erythema (HP:0010783)2.23629682
84Abnormality of molar (HP:0011077)2.22470386
85Abnormality of molar morphology (HP:0011070)2.22470386
86Split foot (HP:0001839)2.19574570
87Abnormality of the dental pulp (HP:0006479)2.19431615
88Aplasia cutis congenita (HP:0001057)2.15256261
89Chondrocalcinosis (HP:0000934)2.13782440
90Blepharitis (HP:0000498)2.13048187
91Conical tooth (HP:0000698)2.12990968
92Abnormality of placental membranes (HP:0011409)2.12956079
93Amniotic constriction ring (HP:0009775)2.12956079
94Generalized muscle weakness (HP:0003324)2.12150684
95Autoamputation (HP:0001218)2.10987546
96Eczematoid dermatitis (HP:0000976)2.07721743
97Fine hair (HP:0002213)2.05999141
98Labial hypoplasia (HP:0000066)2.04001387
99Melanocytic nevus (HP:0000995)2.03649759
100Hamartoma of the eye (HP:0010568)2.00242650
101Nasolacrimal duct obstruction (HP:0000579)2.00151491
102Metabolic alkalosis (HP:0200114)10.2446198
103Curly hair (HP:0002212)1.99886196
104Distal lower limb amyotrophy (HP:0008944)1.97754982
105Abnormality of Sharpey fibers (HP:0100685)1.96907855
106Recurrent corneal erosions (HP:0000495)1.96050212
107Hypergammaglobulinemia (HP:0010702)1.95790442
108Increased connective tissue (HP:0009025)1.95583700
109Long nose (HP:0003189)1.89560038
110Duplicated collecting system (HP:0000081)1.89151553
111Depressed nasal tip (HP:0000437)1.88273857
112Fragile skin (HP:0001030)1.88228272
113Abnormality of purine metabolism (HP:0004352)1.85030053
114Hypotension (HP:0002615)1.84600670
115Hypoplastic female external genitalia (HP:0012815)1.83545617
116Ureteral stenosis (HP:0000071)1.83405756
117Palmoplantar keratoderma (HP:0000982)1.79492811
118Non-midline cleft lip (HP:0100335)1.78960211
119Follicular hyperkeratosis (HP:0007502)1.77954544
120Septate vagina (HP:0001153)1.76827818
121Ridged nail (HP:0001807)1.75935898
122Dry skin (HP:0000958)1.75187820
123Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.75124726
124Nephrocalcinosis (HP:0000121)1.73061550
125Urticaria (HP:0001025)1.72057178
126Glomerulosclerosis (HP:0000096)1.71974839
127Pterygium (HP:0001059)1.71745850
128Short middle phalanx of the 5th finger (HP:0004220)1.71699960
129Abnormality of the lacrimal duct (HP:0011481)1.68576037
130Abnormality of the renal collecting system (HP:0004742)1.68085547
131Fair hair (HP:0002286)1.66826607
132Ureteral obstruction (HP:0006000)1.64761649
133Abnormal platelet function (HP:0011869)1.63955837
134Impaired platelet aggregation (HP:0003540)1.63955837
135Anonychia (HP:0001798)1.63494601
136Hamartoma (HP:0010566)1.63438460
137Premature birth (HP:0001622)1.63390340
138Muscle fiber splitting (HP:0003555)1.62268936
139Abnormality of small intestinal villus morphology (HP:0011472)1.62106494
140Villous atrophy (HP:0011473)1.62106494
141Decreased circulating renin level (HP:0003351)1.60718014
142Abnormal hair laboratory examination (HP:0003328)1.60717897
143Tubulointerstitial fibrosis (HP:0005576)1.59300476
144Abnormality of the nasolacrimal system (HP:0000614)1.57047699
145Erythroderma (HP:0001019)1.55693771
146Generalized hypopigmentation of hair (HP:0011358)1.54315465
147Anhidrosis (HP:0000970)1.53775796
148Hyperkalemia (HP:0002153)1.49621847
149Hyperhidrosis (HP:0000975)1.49442506
150Corneal erosion (HP:0200020)1.48005729
151Ventricular tachycardia (HP:0004756)1.47846321
152Lower limb amyotrophy (HP:0007210)1.47503272
153Adenoma sebaceum (HP:0009720)1.47362510
154Angiofibromas (HP:0010615)1.47362510
155Acanthosis nigricans (HP:0000956)1.46080167
156Abnormality of the distal phalanges of the toes (HP:0010182)1.43517926
157Round ear (HP:0100830)1.42348157
158Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.41889447
159Hypohidrosis (HP:0000966)1.40728109
160Paralysis (HP:0003470)1.37265416
161Tubular atrophy (HP:0000092)1.36725991
162Hyporeflexia of lower limbs (HP:0002600)1.34608280
163Laryngomalacia (HP:0001601)1.34392576
164Ketoacidosis (HP:0001993)1.29502056
165Late onset (HP:0003584)1.28693720

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK39.98017260
2STK245.95404568
3OXSR15.29433025
4FRK4.70717005
5TGFBR14.35204484
6WNK44.08018572
7TRIB33.54331423
8NEK13.42032755
9EEF2K3.30683201
10PIM23.11446185
11MAPKAPK32.30356860
12STK32.04582646
13PKN21.81372466
14MST1R1.72102089
15MAPK71.66048359
16FER1.61703117
17FGFR21.57696088
18ERN11.53782628
19NUAK11.53465768
20BMPR1B1.45210854
21BCR1.43275079
22ACVR1B1.38975134
23STK101.38826802
24EPHB21.36658655
25WNK11.35864783
26SGK21.34336537
27PINK11.34030277
28PRKCE1.33116162
29TAOK31.32188566
30SGK2231.29517475
31SGK4941.29517475
32LRRK21.27607803
33TXK1.25986149
34CAMK1D1.23820536
35BCKDK1.22375663
36IRAK11.22348300
37ADRBK21.21685383
38SGK31.21356035
39EPHA21.20130993
40ERBB31.19914722
41MAP3K31.19734278
42GRK11.18619102
43NME11.16585863
44TAOK11.15364588
45IKBKB1.15332702
46MET1.12234826
47ADRBK11.12172422
48PTK61.07533982
49STK391.06281466
50NLK0.99889052
51DYRK1B0.99811748
52CAMK1G0.88604395
53DMPK0.88115137
54PDK30.87531959
55PDK40.87531959
56AKT30.85683263
57TTN0.85382220
58FGFR30.80894888
59TESK10.78993627
60MAP3K40.78464570
61TYRO30.78178552
62CASK0.77405215
63PRKAA20.76007196
64TRPM70.74443607
65MST40.74170313
66PRKD30.72705232
67STK380.72186231
68LATS20.71108442
69PAK40.70871741
70RPS6KB10.70516996
71TAF10.68636271
72STK38L0.68386333
73MAP3K90.68033218
74MAP4K20.65733144
75PTK20.65583510
76GRK70.65333476
77CDK60.64305078
78NTRK10.63813812
79EPHB10.63772420
80RIPK10.63563314
81EPHA30.62862700
82PRKCG0.62243705
83RPS6KB20.61881380
84BRSK20.61508323
85BMX0.61345524
86CHUK0.59426552
87KIT0.58275022
88FLT30.57837184
89LATS10.55793666
90PDK20.54959068
91MAP3K20.53007337
92PDGFRA0.52168842
93TESK20.52003383
94PIM10.51168140
95MKNK20.49314664
96LIMK10.48296592
97GRK50.47971283
98SIK30.47866706
99PIK3CA0.47074438
100MAP2K30.45686814
101RPS6KA10.45176016
102MAP3K70.44024317
103PIK3CG0.43962860
104MAP3K110.42771961
105MARK30.42681610
106CDK30.41269827
107ABL10.40209086
108MAP2K10.39709210
109PAK20.39518217
110AKT20.38504728
111MATK0.38074729
112ICK0.38058771
113IKBKE0.37846616
114CDK120.36896776
115CSNK1A1L0.36778481
116RPS6KA40.36082870
117DYRK30.36005398
118MTOR0.35684772
119SGK10.35201596
120ILK0.35072612
121MAP2K20.34815336
122FGFR10.33908531
123GRK60.33783697
124MAPKAPK50.33406095
125INSRR0.33133621
126STK110.33079773
127PRKCI0.32937374
128DAPK30.32590855
129IGF1R0.32339491
130MAP3K80.32207139
131PRKD20.32066763
132SIK10.32004973
133PRKCH0.29021902
134DYRK20.28814261
135KSR20.28666011
136CSNK1D0.28525801
137MAPK130.28459905
138GSK3A0.28334453
139CSNK1A10.27763305
140PRKCQ0.27250470
141PDGFRB0.25671801
142RAF10.25493407
143PLK20.25142784
144DDR20.24587477
145TIE10.24216759
146MAP3K10.22780861
147PDPK10.22775124
148MAPKAPK20.22281143
149FGFR40.22206091
150PRKAA10.20111113
151RET0.19577342
152MAPK120.19329871
153MAP2K60.18754426
154PRKD10.18194908
155MAP3K60.18032152
156PAK30.17947611
157EPHA40.17077674
158SRC0.16753980
159MINK10.16449261
160MAP3K50.12838697
161HIPK20.12642851
162TGFBR20.12439516

Predicted pathways (KEGG)

RankGene SetZ-score
1alpha-Linolenic acid metabolism_Homo sapiens_hsa005926.55071472
2Linoleic acid metabolism_Homo sapiens_hsa005915.43820598
3Ether lipid metabolism_Homo sapiens_hsa005654.08129879
4Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049643.94837135
52-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.72340273
6Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049603.45342747
7Circadian rhythm_Homo sapiens_hsa047102.83847683
8Phototransduction_Homo sapiens_hsa047442.79680842
9Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.55645226
10Phenylalanine metabolism_Homo sapiens_hsa003602.53503360
11Sphingolipid metabolism_Homo sapiens_hsa006002.50081839
12Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.36814237
13Cyanoamino acid metabolism_Homo sapiens_hsa004602.35033590
14Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.23768589
15Ovarian steroidogenesis_Homo sapiens_hsa049132.10126738
16Dorso-ventral axis formation_Homo sapiens_hsa043201.96887129
17Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.94117028
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.91269706
19Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.89663506
20Propanoate metabolism_Homo sapiens_hsa006401.87599300
21Sulfur metabolism_Homo sapiens_hsa009201.81357430
22Bile secretion_Homo sapiens_hsa049761.77091863
23Serotonergic synapse_Homo sapiens_hsa047261.76328281
24Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.74744949
25Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.74548459
26Histidine metabolism_Homo sapiens_hsa003401.66341848
27Bladder cancer_Homo sapiens_hsa052191.64998408
28Fatty acid degradation_Homo sapiens_hsa000711.64274898
29Butanoate metabolism_Homo sapiens_hsa006501.63931871
30Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.63520293
31Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.61425399
32Carbon metabolism_Homo sapiens_hsa012001.61305271
33Long-term depression_Homo sapiens_hsa047301.58270257
34beta-Alanine metabolism_Homo sapiens_hsa004101.57622774
35Biosynthesis of amino acids_Homo sapiens_hsa012301.48672941
36Fatty acid elongation_Homo sapiens_hsa000621.40633627
37Vascular smooth muscle contraction_Homo sapiens_hsa042701.40581841
38GnRH signaling pathway_Homo sapiens_hsa049121.40383078
39Arginine biosynthesis_Homo sapiens_hsa002201.39379761
40Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.35368753
41Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.34853186
42Gastric acid secretion_Homo sapiens_hsa049711.32539415
43Glycerophospholipid metabolism_Homo sapiens_hsa005641.29981833
44Steroid hormone biosynthesis_Homo sapiens_hsa001401.24222047
45Pyruvate metabolism_Homo sapiens_hsa006201.24086590
46Tight junction_Homo sapiens_hsa045301.21548271
47Fatty acid metabolism_Homo sapiens_hsa012121.19969945
48Renin secretion_Homo sapiens_hsa049241.15658718
49ECM-receptor interaction_Homo sapiens_hsa045121.13684755
50Tyrosine metabolism_Homo sapiens_hsa003501.11470033
51ABC transporters_Homo sapiens_hsa020101.10436286
52Glutathione metabolism_Homo sapiens_hsa004801.07628336
53Ras signaling pathway_Homo sapiens_hsa040141.04237088
54Nitrogen metabolism_Homo sapiens_hsa009101.03679774
55Glutamatergic synapse_Homo sapiens_hsa047241.01268764
56Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.01128727
57Retinol metabolism_Homo sapiens_hsa008301.01026260
58Chemical carcinogenesis_Homo sapiens_hsa052041.00481950
59Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.00344655
60Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.98639743
61Tryptophan metabolism_Homo sapiens_hsa003800.97857332
62Carbohydrate digestion and absorption_Homo sapiens_hsa049730.97122659
63Mineral absorption_Homo sapiens_hsa049780.92980683
64Glioma_Homo sapiens_hsa052140.91363584
65Focal adhesion_Homo sapiens_hsa045100.91183397
66Collecting duct acid secretion_Homo sapiens_hsa049660.89427017
67Choline metabolism in cancer_Homo sapiens_hsa052310.88617613
68Protein digestion and absorption_Homo sapiens_hsa049740.87674951
69Central carbon metabolism in cancer_Homo sapiens_hsa052300.86977094
70p53 signaling pathway_Homo sapiens_hsa041150.82792126
71Thyroid cancer_Homo sapiens_hsa052160.82374489
72Leukocyte transendothelial migration_Homo sapiens_hsa046700.82330251
73Staphylococcus aureus infection_Homo sapiens_hsa051500.82271907
74Small cell lung cancer_Homo sapiens_hsa052220.81241637
75Acute myeloid leukemia_Homo sapiens_hsa052210.80918100
76PPAR signaling pathway_Homo sapiens_hsa033200.78673516
77Adherens junction_Homo sapiens_hsa045200.77951386
78Arginine and proline metabolism_Homo sapiens_hsa003300.77350006
79Hippo signaling pathway_Homo sapiens_hsa043900.76443436
80Peroxisome_Homo sapiens_hsa041460.75638477
81Oxytocin signaling pathway_Homo sapiens_hsa049210.71923367
82Proteoglycans in cancer_Homo sapiens_hsa052050.71034037
83Lysine degradation_Homo sapiens_hsa003100.69891760
84Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.69854438
85Adipocytokine signaling pathway_Homo sapiens_hsa049200.67931264
86Notch signaling pathway_Homo sapiens_hsa043300.65755791
87Vitamin digestion and absorption_Homo sapiens_hsa049770.65575000
88Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.65432961
89Cardiac muscle contraction_Homo sapiens_hsa042600.65306402
90Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.65115428
91Olfactory transduction_Homo sapiens_hsa047400.63849625
92Circadian entrainment_Homo sapiens_hsa047130.62317955
93Endometrial cancer_Homo sapiens_hsa052130.62290389
94NOD-like receptor signaling pathway_Homo sapiens_hsa046210.61247180
95HIF-1 signaling pathway_Homo sapiens_hsa040660.60910983
96Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.60162149
97Salivary secretion_Homo sapiens_hsa049700.59224870
98Insulin resistance_Homo sapiens_hsa049310.57600052
99Chronic myeloid leukemia_Homo sapiens_hsa052200.57151399
100VEGF signaling pathway_Homo sapiens_hsa043700.56196491
101Phosphatidylinositol signaling system_Homo sapiens_hsa040700.55916441
102Taste transduction_Homo sapiens_hsa047420.55017040
103Hedgehog signaling pathway_Homo sapiens_hsa043400.54719555
104Amoebiasis_Homo sapiens_hsa051460.54667247
105Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.53999619
106Alzheimers disease_Homo sapiens_hsa050100.53447219
107Melanogenesis_Homo sapiens_hsa049160.53174186
108Hepatitis C_Homo sapiens_hsa051600.52777301
109Glucagon signaling pathway_Homo sapiens_hsa049220.52563304
110Regulation of actin cytoskeleton_Homo sapiens_hsa048100.52027121
111MicroRNAs in cancer_Homo sapiens_hsa052060.51211280
112Sphingolipid signaling pathway_Homo sapiens_hsa040710.50356809
113Calcium signaling pathway_Homo sapiens_hsa040200.48615945
114Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.46817540
115Platelet activation_Homo sapiens_hsa046110.46740064
116cAMP signaling pathway_Homo sapiens_hsa040240.46253072
117Pentose phosphate pathway_Homo sapiens_hsa000300.46004070
118Thyroid hormone signaling pathway_Homo sapiens_hsa049190.45338195
119Thyroid hormone synthesis_Homo sapiens_hsa049180.43778055
120Melanoma_Homo sapiens_hsa052180.43317033
121Arachidonic acid metabolism_Homo sapiens_hsa005900.41993540
122Inositol phosphate metabolism_Homo sapiens_hsa005620.41038684
123Primary bile acid biosynthesis_Homo sapiens_hsa001200.40894018
124ErbB signaling pathway_Homo sapiens_hsa040120.40233651
125Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.39923751
126MAPK signaling pathway_Homo sapiens_hsa040100.39608708
127Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.38930420
128Cysteine and methionine metabolism_Homo sapiens_hsa002700.38896714
129Regulation of autophagy_Homo sapiens_hsa041400.37712275
130Non-small cell lung cancer_Homo sapiens_hsa052230.37193984
131Fructose and mannose metabolism_Homo sapiens_hsa000510.37115462
132Intestinal immune network for IgA production_Homo sapiens_hsa046720.36748633
133Renal cell carcinoma_Homo sapiens_hsa052110.36123624
134Dilated cardiomyopathy_Homo sapiens_hsa054140.35892461
135Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.35208853
136Caffeine metabolism_Homo sapiens_hsa002320.35203927
137Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.34941349
138Dopaminergic synapse_Homo sapiens_hsa047280.34831099
139Pertussis_Homo sapiens_hsa051330.34595864
140Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.33180529
141AMPK signaling pathway_Homo sapiens_hsa041520.33126555
142Phospholipase D signaling pathway_Homo sapiens_hsa040720.33091765
143Fat digestion and absorption_Homo sapiens_hsa049750.32749803
144Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.32636599
145Toxoplasmosis_Homo sapiens_hsa051450.32531315
146TGF-beta signaling pathway_Homo sapiens_hsa043500.31853410
147Rap1 signaling pathway_Homo sapiens_hsa040150.31836631
148Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.31602045
149Basal cell carcinoma_Homo sapiens_hsa052170.29638965
150Oxidative phosphorylation_Homo sapiens_hsa001900.28722661
151Wnt signaling pathway_Homo sapiens_hsa043100.28716141
152Pancreatic secretion_Homo sapiens_hsa049720.28475252
153Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.28100559
154Endocytosis_Homo sapiens_hsa041440.28028310
155Axon guidance_Homo sapiens_hsa043600.28016846
156Glycerolipid metabolism_Homo sapiens_hsa005610.27192097
157Rheumatoid arthritis_Homo sapiens_hsa053230.25384108
158Tuberculosis_Homo sapiens_hsa051520.25045620
159Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.24437364
160Pentose and glucuronate interconversions_Homo sapiens_hsa000400.24081105
161Transcriptional misregulation in cancer_Homo sapiens_hsa052020.21792374
162Jak-STAT signaling pathway_Homo sapiens_hsa046300.21365819
163Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.20501029
164Amphetamine addiction_Homo sapiens_hsa050310.19254135
165Aldosterone synthesis and secretion_Homo sapiens_hsa049250.19031450

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