

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of cell killing (GO:0031342) | 6.29172199 |
| 2 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.29172199 |
| 3 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.10537909 |
| 4 | positive regulation by symbiont of host defense response (GO:0052509) | 5.89168215 |
| 5 | modulation by symbiont of host defense response (GO:0052031) | 5.89168215 |
| 6 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.89168215 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.89168215 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.89168215 |
| 9 | modulation by symbiont of host immune response (GO:0052553) | 5.89168215 |
| 10 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.72354413 |
| 11 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.53131848 |
| 12 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.51730416 |
| 13 | neutrophil activation involved in immune response (GO:0002283) | 5.29652535 |
| 14 | detection of other organism (GO:0098543) | 5.22618753 |
| 15 | detection of bacterium (GO:0016045) | 5.06997408 |
| 16 | macrophage activation involved in immune response (GO:0002281) | 5.01130635 |
| 17 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.00826675 |
| 18 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.00667155 |
| 19 | response to peptidoglycan (GO:0032494) | 4.80103258 |
| 20 | leukocyte aggregation (GO:0070486) | 4.55647786 |
| 21 | negative regulation of interleukin-12 production (GO:0032695) | 4.50161266 |
| 22 | detection of external biotic stimulus (GO:0098581) | 4.46531591 |
| 23 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.39157105 |
| 24 | immunoglobulin mediated immune response (GO:0016064) | 4.37718746 |
| 25 | respiratory burst (GO:0045730) | 4.28495247 |
| 26 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.27392795 |
| 27 | detection of molecule of bacterial origin (GO:0032490) | 4.25166715 |
| 28 | neutrophil activation (GO:0042119) | 4.19179977 |
| 29 | cellular extravasation (GO:0045123) | 4.18325983 |
| 30 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.17494720 |
| 31 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.16571423 |
| 32 | regulation of gamma-delta T cell activation (GO:0046643) | 4.10485483 |
| 33 | leukocyte migration involved in inflammatory response (GO:0002523) | 4.09107077 |
| 34 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.08366646 |
| 35 | response to host immune response (GO:0052572) | 4.08366646 |
| 36 | detection of biotic stimulus (GO:0009595) | 3.90251176 |
| 37 | granulocyte activation (GO:0036230) | 3.87952974 |
| 38 | microglial cell activation (GO:0001774) | 3.86094581 |
| 39 | cellular response to type I interferon (GO:0071357) | 3.85965191 |
| 40 | type I interferon signaling pathway (GO:0060337) | 3.85965191 |
| 41 | response to interleukin-15 (GO:0070672) | 3.85869472 |
| 42 | response to type I interferon (GO:0034340) | 3.82927446 |
| 43 | B cell receptor signaling pathway (GO:0050853) | 3.74939916 |
| 44 | neutrophil mediated immunity (GO:0002446) | 3.73789030 |
| 45 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.73738585 |
| 46 | response to host (GO:0075136) | 3.73738585 |
| 47 | response to host defenses (GO:0052200) | 3.73738585 |
| 48 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.70132943 |
| 49 | myeloid cell activation involved in immune response (GO:0002275) | 3.68680756 |
| 50 | regulation of mast cell degranulation (GO:0043304) | 3.66639825 |
| 51 | macrophage activation (GO:0042116) | 3.61598617 |
| 52 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.60393670 |
| 53 | cellular response to interleukin-15 (GO:0071350) | 3.54697356 |
| 54 | negative regulation of T cell mediated immunity (GO:0002710) | 3.52769330 |
| 55 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.50615731 |
| 56 | defense response to protozoan (GO:0042832) | 3.50207577 |
| 57 | B cell mediated immunity (GO:0019724) | 3.48376666 |
| 58 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.47280326 |
| 59 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.46265991 |
| 60 | germinal center formation (GO:0002467) | 3.43782156 |
| 61 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.37242019 |
| 62 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.36529336 |
| 63 | response to muramyl dipeptide (GO:0032495) | 3.33688256 |
| 64 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.32390486 |
| 65 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.31824208 |
| 66 | regulation of T cell tolerance induction (GO:0002664) | 3.30933691 |
| 67 | positive regulation of mast cell activation (GO:0033005) | 3.30908058 |
| 68 | regulation of B cell differentiation (GO:0045577) | 3.24888783 |
| 69 | regulation of leukocyte degranulation (GO:0043300) | 3.21804524 |
| 70 | regulation of mast cell activation (GO:0033003) | 3.21128202 |
| 71 | myeloid leukocyte mediated immunity (GO:0002444) | 3.21079957 |
| 72 | positive regulation of interferon-alpha production (GO:0032727) | 3.18338413 |
| 73 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.17953776 |
| 74 | negative regulation of phagocytosis (GO:0050765) | 3.17509209 |
| 75 | positive regulation of B cell differentiation (GO:0045579) | 3.17493573 |
| 76 | regulation of tolerance induction (GO:0002643) | 3.17091999 |
| 77 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.16377772 |
| 78 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.12282121 |
| 79 | response to protozoan (GO:0001562) | 3.12066793 |
| 80 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.11032278 |
| 81 | leukocyte degranulation (GO:0043299) | 3.09343562 |
| 82 | regulation of interferon-alpha production (GO:0032647) | 3.05348749 |
| 83 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.04771962 |
| 84 | positive thymic T cell selection (GO:0045059) | 3.04437912 |
| 85 | regulation of antigen processing and presentation (GO:0002577) | 3.01922756 |
| 86 | negative regulation of innate immune response (GO:0045824) | 2.97138142 |
| 87 | T cell migration (GO:0072678) | 2.97044731 |
| 88 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.96969175 |
| 89 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.96698439 |
| 90 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.96698439 |
| 91 | negative thymic T cell selection (GO:0045060) | 2.96652757 |
| 92 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.95121503 |
| 93 | negative regulation of alpha-beta T cell activation (GO:0046636) | 2.93539145 |
| 94 | negative regulation of interleukin-6 production (GO:0032715) | 2.93428035 |
| 95 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.91581594 |
| 96 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.91581594 |
| 97 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.90414846 |
| 98 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.89034444 |
| 99 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.88933910 |
| 100 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.88390590 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.89273521 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.54092201 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.51615228 |
| 4 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.71603874 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.71304465 |
| 6 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.27861800 |
| 7 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.25866774 |
| 8 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.25596753 |
| 9 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.11277791 |
| 10 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.09342007 |
| 11 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.87771877 |
| 12 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.84244378 |
| 13 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.79681680 |
| 14 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.71283780 |
| 15 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.71112959 |
| 16 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.68657854 |
| 17 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.59463808 |
| 18 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.55935773 |
| 19 | * SPI1_23127762_ChIP-Seq_K562_Human | 2.54222044 |
| 20 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.51022800 |
| 21 | MAF_26560356_Chip-Seq_TH1_Human | 2.45644086 |
| 22 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.40965952 |
| 23 | MYC_22102868_ChIP-Seq_BL_Human | 2.40582191 |
| 24 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.40548782 |
| 25 | MYB_26560356_Chip-Seq_TH2_Human | 2.34957114 |
| 26 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.31944554 |
| 27 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.24742805 |
| 28 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.16783291 |
| 29 | UTX_26944678_Chip-Seq_JUKART_Human | 2.16699280 |
| 30 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.13146810 |
| 31 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.12754569 |
| 32 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.09760964 |
| 33 | MYB_26560356_Chip-Seq_TH1_Human | 2.04044867 |
| 34 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.98754251 |
| 35 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.96785613 |
| 36 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.95762739 |
| 37 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.91640101 |
| 38 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.88785763 |
| 39 | MAF_26560356_Chip-Seq_TH2_Human | 1.82124330 |
| 40 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.80927659 |
| 41 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.71104930 |
| 42 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.69186958 |
| 43 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.64925396 |
| 44 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.63886910 |
| 45 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.63144664 |
| 46 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.63003606 |
| 47 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.59308052 |
| 48 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.57203766 |
| 49 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.55691665 |
| 50 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.54106789 |
| 51 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.53960741 |
| 52 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.52065016 |
| 53 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.51549449 |
| 54 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.49029352 |
| 55 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.48592538 |
| 56 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.41113268 |
| 57 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.37919916 |
| 58 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.35276445 |
| 59 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.34501751 |
| 60 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.33803626 |
| 61 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.32871059 |
| 62 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.30997991 |
| 63 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.30182104 |
| 64 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.29632039 |
| 65 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.29558306 |
| 66 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.28465469 |
| 67 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.27445522 |
| 68 | * GATA3_26560356_Chip-Seq_TH2_Human | 1.27162841 |
| 69 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.26633079 |
| 70 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.26228268 |
| 71 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.24559487 |
| 72 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.23778486 |
| 73 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.20780347 |
| 74 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.18333876 |
| 75 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.16125919 |
| 76 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.15587187 |
| 77 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.15498535 |
| 78 | * BCL6_27268052_Chip-Seq_Bcells_Human | 1.14968284 |
| 79 | GATA1_22025678_ChIP-Seq_K562_Human | 1.14599537 |
| 80 | GATA1_19941826_ChIP-Seq_K562_Human | 1.14434179 |
| 81 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12656002 |
| 82 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.10752340 |
| 83 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.10324103 |
| 84 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.06874280 |
| 85 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.06801416 |
| 86 | * BCOR_27268052_Chip-Seq_Bcells_Human | 1.06108921 |
| 87 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.05276555 |
| 88 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.04336969 |
| 89 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.03974474 |
| 90 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.03693017 |
| 91 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.94393054 |
| 92 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.89651341 |
| 93 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.88902417 |
| 94 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88420851 |
| 95 | GATA2_19941826_ChIP-Seq_K562_Human | 0.86469597 |
| 96 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.84178053 |
| 97 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.83662227 |
| 98 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.82950481 |
| 99 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.81453995 |
| 100 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.79960898 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 4.73698969 |
| 2 | MP0003436_decreased_susceptibility_to | 4.31544505 |
| 3 | MP0003303_peritoneal_inflammation | 4.06643956 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.90541192 |
| 5 | MP0002419_abnormal_innate_immunity | 3.22493694 |
| 6 | MP0005671_abnormal_response_to | 3.17761944 |
| 7 | MP0001790_abnormal_immune_system | 3.13936809 |
| 8 | MP0005387_immune_system_phenotype | 3.13936809 |
| 9 | MP0009785_altered_susceptibility_to | 3.11475821 |
| 10 | MP0001800_abnormal_humoral_immune | 3.09194348 |
| 11 | MP0000685_abnormal_immune_system | 3.02868754 |
| 12 | MP0005025_abnormal_response_to | 3.01020066 |
| 13 | MP0005000_abnormal_immune_tolerance | 3.00925349 |
| 14 | MP0002723_abnormal_immune_serum | 2.73188274 |
| 15 | MP0002452_abnormal_antigen_presenting | 2.67056287 |
| 16 | MP0006082_CNS_inflammation | 2.66961582 |
| 17 | MP0002420_abnormal_adaptive_immunity | 2.63637617 |
| 18 | MP0001819_abnormal_immune_cell | 2.60969297 |
| 19 | MP0002148_abnormal_hypersensitivity_rea | 2.49911402 |
| 20 | MP0003300_gastrointestinal_ulcer | 2.40559688 |
| 21 | MP0003191_abnormal_cellular_cholesterol | 2.23556822 |
| 22 | MP0001533_abnormal_skeleton_physiology | 2.18478411 |
| 23 | MP0003763_abnormal_thymus_physiology | 2.11686991 |
| 24 | MP0002405_respiratory_system_inflammati | 2.03919136 |
| 25 | MP0002398_abnormal_bone_marrow | 1.97432000 |
| 26 | MP0000716_abnormal_immune_system | 1.95860983 |
| 27 | MP0008260_abnormal_autophagy | 1.93218946 |
| 28 | MP0005464_abnormal_platelet_physiology | 1.91509402 |
| 29 | MP0001845_abnormal_inflammatory_respons | 1.85551463 |
| 30 | MP0010155_abnormal_intestine_physiology | 1.85275465 |
| 31 | MP0003172_abnormal_lysosome_physiology | 1.82929100 |
| 32 | MP0003183_abnormal_peptide_metabolism | 1.74892261 |
| 33 | MP0009278_abnormal_bone_marrow | 1.74124003 |
| 34 | MP0004947_skin_inflammation | 1.70796998 |
| 35 | MP0002132_abnormal_respiratory_system | 1.66442207 |
| 36 | MP0000689_abnormal_spleen_morphology | 1.64007791 |
| 37 | MP0009764_decreased_sensitivity_to | 1.59556115 |
| 38 | MP0002722_abnormal_immune_system | 1.58655446 |
| 39 | MP0005451_abnormal_body_composition | 1.57633797 |
| 40 | MP0009333_abnormal_splenocyte_physiolog | 1.56447541 |
| 41 | MP0004510_myositis | 1.55325989 |
| 42 | MP0000465_gastrointestinal_hemorrhage | 1.55209392 |
| 43 | MP0002429_abnormal_blood_cell | 1.54307804 |
| 44 | MP0008469_abnormal_protein_level | 1.53816267 |
| 45 | MP0005310_abnormal_salivary_gland | 1.52572582 |
| 46 | MP0003828_pulmonary_edema | 1.49936215 |
| 47 | MP0002396_abnormal_hematopoietic_system | 1.47703301 |
| 48 | MP0003866_abnormal_defecation | 1.46932664 |
| 49 | MP0002277_abnormal_respiratory_mucosa | 1.34326096 |
| 50 | MP0000703_abnormal_thymus_morphology | 1.33812041 |
| 51 | MP0003075_altered_response_to | 1.32361618 |
| 52 | MP0000858_altered_metastatic_potential | 1.32101053 |
| 53 | MP0004883_abnormal_blood_vessel | 1.31803012 |
| 54 | MP0004381_abnormal_hair_follicle | 1.26262926 |
| 55 | MP0001545_abnormal_hematopoietic_system | 1.24327764 |
| 56 | MP0005397_hematopoietic_system_phenotyp | 1.24327764 |
| 57 | MP0005058_abnormal_lysosome_morphology | 1.20097162 |
| 58 | MP0002998_abnormal_bone_remodeling | 1.19735620 |
| 59 | MP0001851_eye_inflammation | 1.15804004 |
| 60 | MP0003690_abnormal_glial_cell | 1.05223780 |
| 61 | MP0000343_altered_response_to | 1.03277768 |
| 62 | MP0005164_abnormal_response_to | 1.02914036 |
| 63 | MP0005166_decreased_susceptibility_to | 1.02339700 |
| 64 | MP0002138_abnormal_hepatobiliary_system | 1.01631237 |
| 65 | MP0001853_heart_inflammation | 0.97911636 |
| 66 | MP0002166_altered_tumor_susceptibility | 0.96862566 |
| 67 | MP0008004_abnormal_stomach_pH | 0.94374610 |
| 68 | MP0003806_abnormal_nucleotide_metabolis | 0.93467770 |
| 69 | MP0001873_stomach_inflammation | 0.90113079 |
| 70 | MP0003448_altered_tumor_morphology | 0.88866714 |
| 71 | MP0009763_increased_sensitivity_to | 0.86803689 |
| 72 | MP0005390_skeleton_phenotype | 0.86612465 |
| 73 | MP0001663_abnormal_digestive_system | 0.86136475 |
| 74 | MP0000604_amyloidosis | 0.84480132 |
| 75 | MP0000490_abnormal_crypts_of | 0.79743843 |
| 76 | MP0005075_abnormal_melanosome_morpholog | 0.76862044 |
| 77 | MP0003656_abnormal_erythrocyte_physiolo | 0.76046687 |
| 78 | MP0003045_fibrosis | 0.75739168 |
| 79 | MP0004808_abnormal_hematopoietic_stem | 0.74618514 |
| 80 | MP0002933_joint_inflammation | 0.70711794 |
| 81 | MP0008874_decreased_physiological_sensi | 0.69005691 |
| 82 | MP0009765_abnormal_xenobiotic_induced | 0.67887945 |
| 83 | MP0002332_abnormal_exercise_endurance | 0.67200587 |
| 84 | MP0009840_abnormal_foam_cell | 0.64470538 |
| 85 | MP0003795_abnormal_bone_structure | 0.63447663 |
| 86 | MP0001986_abnormal_taste_sensitivity | 0.63131804 |
| 87 | MP0000249_abnormal_blood_vessel | 0.62282386 |
| 88 | MP0003221_abnormal_cardiomyocyte_apopto | 0.59964955 |
| 89 | MP0002006_tumorigenesis | 0.59627917 |
| 90 | MP0000015_abnormal_ear_pigmentation | 0.56697321 |
| 91 | MP0005319_abnormal_enzyme/_coenzyme | 0.56269771 |
| 92 | MP0002928_abnormal_bile_duct | 0.53234553 |
| 93 | MP0003091_abnormal_cell_migration | 0.52371739 |
| 94 | MP0002693_abnormal_pancreas_physiology | 0.48236743 |
| 95 | MP0002019_abnormal_tumor_incidence | 0.47472299 |
| 96 | MP0000609_abnormal_liver_physiology | 0.46079635 |
| 97 | MP0005381_digestive/alimentary_phenotyp | 0.45918086 |
| 98 | MP0003453_abnormal_keratinocyte_physiol | 0.45547167 |
| 99 | MP0005167_abnormal_blood-brain_barrier | 0.44418751 |
| 100 | MP0005083_abnormal_biliary_tract | 0.43866434 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 7.10942246 |
| 2 | Recurrent bacterial skin infections (HP:0005406) | 6.31251116 |
| 3 | Recurrent abscess formation (HP:0002722) | 6.31245069 |
| 4 | Myositis (HP:0100614) | 5.77680560 |
| 5 | Abnormality of macrophages (HP:0004311) | 5.72266267 |
| 6 | Orchitis (HP:0100796) | 5.52725776 |
| 7 | Recurrent gram-negative bacterial infections (HP:0005420) | 5.36526579 |
| 8 | Retrobulbar optic neuritis (HP:0100654) | 5.26176313 |
| 9 | Optic neuritis (HP:0100653) | 5.26176313 |
| 10 | Stomatitis (HP:0010280) | 4.85619681 |
| 11 | Mediastinal lymphadenopathy (HP:0100721) | 4.64034001 |
| 12 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.44480672 |
| 13 | Chronic obstructive pulmonary disease (HP:0006510) | 4.42202701 |
| 14 | Obstructive lung disease (HP:0006536) | 4.42202701 |
| 15 | Meningitis (HP:0001287) | 4.37610966 |
| 16 | Recurrent fungal infections (HP:0002841) | 4.26846781 |
| 17 | Gastrointestinal infarctions (HP:0005244) | 4.22056153 |
| 18 | Recurrent skin infections (HP:0001581) | 4.04421613 |
| 19 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.00619402 |
| 20 | Hypochromic microcytic anemia (HP:0004840) | 3.84186061 |
| 21 | Keratoconjunctivitis sicca (HP:0001097) | 3.79966819 |
| 22 | Encephalitis (HP:0002383) | 3.76990287 |
| 23 | Vasculitis (HP:0002633) | 3.74759583 |
| 24 | Urticaria (HP:0001025) | 3.70202824 |
| 25 | Cellulitis (HP:0100658) | 3.66579370 |
| 26 | Increased IgE level (HP:0003212) | 3.62727432 |
| 27 | Gingivitis (HP:0000230) | 3.62690824 |
| 28 | Spontaneous hematomas (HP:0007420) | 3.59388935 |
| 29 | Keratoconjunctivitis (HP:0001096) | 3.51415613 |
| 30 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.50941948 |
| 31 | Recurrent cutaneous fungal infections (HP:0011370) | 3.50941948 |
| 32 | Hypochromic anemia (HP:0001931) | 3.35223820 |
| 33 | Chest pain (HP:0100749) | 3.15208471 |
| 34 | Pulmonary infiltrates (HP:0002113) | 3.13098415 |
| 35 | Prolonged bleeding time (HP:0003010) | 3.09535931 |
| 36 | Hemoptysis (HP:0002105) | 3.07213404 |
| 37 | Episodic fever (HP:0001954) | 2.95370722 |
| 38 | Recurrent viral infections (HP:0004429) | 2.90879008 |
| 39 | Inflammation of the large intestine (HP:0002037) | 2.90728020 |
| 40 | T lymphocytopenia (HP:0005403) | 2.90533617 |
| 41 | Osteomyelitis (HP:0002754) | 2.86365121 |
| 42 | Abnormality of T cell number (HP:0011839) | 2.83067192 |
| 43 | Gastrointestinal inflammation (HP:0004386) | 2.80145326 |
| 44 | Increased IgM level (HP:0003496) | 2.78806566 |
| 45 | Anorexia (HP:0002039) | 2.76832911 |
| 46 | Gingival bleeding (HP:0000225) | 2.75146684 |
| 47 | Arterial thrombosis (HP:0004420) | 2.74623908 |
| 48 | Leukocytosis (HP:0001974) | 2.73905256 |
| 49 | Lymphopenia (HP:0001888) | 2.66653409 |
| 50 | Petechiae (HP:0000967) | 2.65668526 |
| 51 | Pulmonary embolism (HP:0002204) | 2.65555103 |
| 52 | Peritonitis (HP:0002586) | 2.63624837 |
| 53 | Agammaglobulinemia (HP:0004432) | 2.62553510 |
| 54 | Sepsis (HP:0100806) | 2.61991406 |
| 55 | Panhypogammaglobulinemia (HP:0003139) | 2.61680872 |
| 56 | Epistaxis (HP:0000421) | 2.58426054 |
| 57 | Abnormality of T cells (HP:0002843) | 2.57305913 |
| 58 | Pustule (HP:0200039) | 2.57124845 |
| 59 | Gastrointestinal stroma tumor (HP:0100723) | 2.50635992 |
| 60 | Amyloidosis (HP:0011034) | 2.50436646 |
| 61 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.49619373 |
| 62 | Abnormality of the pleura (HP:0002103) | 2.44162387 |
| 63 | Granulocytopenia (HP:0001913) | 2.43449572 |
| 64 | Colitis (HP:0002583) | 2.43392784 |
| 65 | Microcytic anemia (HP:0001935) | 2.42029022 |
| 66 | Gangrene (HP:0100758) | 2.41064939 |
| 67 | Recurrent pneumonia (HP:0006532) | 2.38970722 |
| 68 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.36905462 |
| 69 | Recurrent bronchitis (HP:0002837) | 2.33477709 |
| 70 | Hypergammaglobulinemia (HP:0010702) | 2.31015759 |
| 71 | Abnormality of T cell physiology (HP:0011840) | 2.26316045 |
| 72 | Abnormality of the peritoneum (HP:0002585) | 2.24989585 |
| 73 | Recurrent sinusitis (HP:0011108) | 2.20072185 |
| 74 | Purpura (HP:0000979) | 2.19826941 |
| 75 | IgM deficiency (HP:0002850) | 2.19748144 |
| 76 | Skin ulcer (HP:0200042) | 2.15778041 |
| 77 | Abnormality of glycolipid metabolism (HP:0010969) | 2.12851220 |
| 78 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.12851220 |
| 79 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.12851220 |
| 80 | Glomerulopathy (HP:0100820) | 2.12055332 |
| 81 | Hepatosplenomegaly (HP:0001433) | 2.12022626 |
| 82 | Recurrent lower respiratory tract infections (HP:0002783) | 2.11576198 |
| 83 | Abnormality of the endocardium (HP:0004306) | 2.11525257 |
| 84 | Premature loss of primary teeth (HP:0006323) | 2.10364856 |
| 85 | Chronic otitis media (HP:0000389) | 2.10045008 |
| 86 | Loss of speech (HP:0002371) | 2.09497035 |
| 87 | Increased cerebral lipofuscin (HP:0011813) | 2.09383302 |
| 88 | Abnormality of the pericardium (HP:0001697) | 2.05845360 |
| 89 | Eosinophilia (HP:0001880) | 2.04189203 |
| 90 | Increased serum ferritin (HP:0003281) | 2.03160880 |
| 91 | Restrictive lung disease (HP:0002091) | 2.02358400 |
| 92 | Slow saccadic eye movements (HP:0000514) | 1.98846936 |
| 93 | Acne (HP:0001061) | 1.96563599 |
| 94 | Keratitis (HP:0000491) | 1.95936688 |
| 95 | Skin rash (HP:0000988) | 1.95771988 |
| 96 | Vertigo (HP:0002321) | 1.92705022 |
| 97 | Polyneuropathy (HP:0001271) | 1.92177261 |
| 98 | Viral hepatitis (HP:0006562) | 1.91922093 |
| 99 | Abnormality of iron homeostasis (HP:0011031) | 1.91852792 |
| 100 | Verrucae (HP:0200043) | 1.91065235 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.94987111 |
| 2 | IRAK4 | 3.79252557 |
| 3 | MAP4K1 | 3.78850824 |
| 4 | BLK | 3.43994670 |
| 5 | ERN1 | 2.95106969 |
| 6 | TYK2 | 2.84095915 |
| 7 | MAP2K3 | 2.79025071 |
| 8 | CSK | 2.70594803 |
| 9 | FES | 2.39363683 |
| 10 | TNK2 | 2.35214919 |
| 11 | GRK6 | 2.23124191 |
| 12 | PRPF4B | 2.12513739 |
| 13 | ZAP70 | 1.90186875 |
| 14 | TAOK1 | 1.89822970 |
| 15 | FGR | 1.88956991 |
| 16 | BTK | 1.86445561 |
| 17 | EPHB1 | 1.84988995 |
| 18 | JAK3 | 1.84878570 |
| 19 | TXK | 1.82929062 |
| 20 | MAP3K14 | 1.81316462 |
| 21 | SYK | 1.80265672 |
| 22 | MAP3K11 | 1.78219679 |
| 23 | IKBKE | 1.75900218 |
| 24 | HCK | 1.73432892 |
| 25 | MAP3K3 | 1.72419929 |
| 26 | TBK1 | 1.62192594 |
| 27 | SIK3 | 1.50782646 |
| 28 | LYN | 1.49350795 |
| 29 | MAP3K13 | 1.40011960 |
| 30 | JAK2 | 1.36222383 |
| 31 | JAK1 | 1.31067326 |
| 32 | CSF1R | 1.27336695 |
| 33 | MAP3K1 | 1.20546828 |
| 34 | KSR2 | 1.19382343 |
| 35 | KIT | 1.18455059 |
| 36 | TESK2 | 1.18089200 |
| 37 | LCK | 1.16885884 |
| 38 | SIK2 | 1.13497799 |
| 39 | MARK3 | 1.11226976 |
| 40 | MATK | 1.10596479 |
| 41 | YES1 | 1.08458603 |
| 42 | TAOK2 | 1.06486879 |
| 43 | TAOK3 | 1.06274200 |
| 44 | IKBKB | 1.02210893 |
| 45 | MARK2 | 0.95855307 |
| 46 | ITK | 0.95142404 |
| 47 | BMPR2 | 0.95072571 |
| 48 | IRAK1 | 0.94972271 |
| 49 | IRAK2 | 0.91993569 |
| 50 | PRKD2 | 0.89211500 |
| 51 | CDK19 | 0.89052778 |
| 52 | STK10 | 0.88071182 |
| 53 | PDK1 | 0.83099277 |
| 54 | TEC | 0.82572296 |
| 55 | TRIB3 | 0.81012940 |
| 56 | PTK6 | 0.80142908 |
| 57 | SMG1 | 0.75272459 |
| 58 | PDPK1 | 0.70817713 |
| 59 | TGFBR2 | 0.69226953 |
| 60 | CDC42BPA | 0.69022777 |
| 61 | FYN | 0.68342236 |
| 62 | MAP3K6 | 0.63200213 |
| 63 | LRRK2 | 0.62584277 |
| 64 | IRAK3 | 0.61280538 |
| 65 | MAPK12 | 0.57585000 |
| 66 | SIK1 | 0.57145090 |
| 67 | MAP3K5 | 0.56531628 |
| 68 | MAP3K7 | 0.56496500 |
| 69 | PRKCQ | 0.56486180 |
| 70 | GRK7 | 0.56248207 |
| 71 | FGFR4 | 0.56133698 |
| 72 | PTK2B | 0.54096727 |
| 73 | DYRK1B | 0.52904489 |
| 74 | STK11 | 0.51451991 |
| 75 | PIM1 | 0.51156651 |
| 76 | MAPK7 | 0.49045822 |
| 77 | HIPK2 | 0.48154135 |
| 78 | MAP2K4 | 0.48097300 |
| 79 | FGFR3 | 0.47792630 |
| 80 | MAP3K2 | 0.44862842 |
| 81 | RAF1 | 0.44378548 |
| 82 | RPS6KC1 | 0.43039474 |
| 83 | RPS6KL1 | 0.43039474 |
| 84 | EPHA3 | 0.42384970 |
| 85 | MAP2K6 | 0.40302654 |
| 86 | MAPKAPK2 | 0.39218957 |
| 87 | SGK3 | 0.38021608 |
| 88 | RPS6KA6 | 0.35946194 |
| 89 | DAPK2 | 0.35928423 |
| 90 | KSR1 | 0.35464185 |
| 91 | PIK3CG | 0.35185768 |
| 92 | PRKCZ | 0.32124056 |
| 93 | NLK | 0.31744507 |
| 94 | STK38 | 0.31688311 |
| 95 | RET | 0.30807722 |
| 96 | PRKG2 | 0.30778108 |
| 97 | CAMKK1 | 0.30462178 |
| 98 | PRKCD | 0.29926942 |
| 99 | MAP3K8 | 0.27986141 |
| 100 | MOS | 0.26934205 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Leishmaniasis_Homo sapiens_hsa05140 | 3.16415052 |
| 2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 3.03365146 |
| 3 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.92768061 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.76264522 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.71052577 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.53350602 |
| 7 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.44689465 |
| 8 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.33434332 |
| 9 | Tuberculosis_Homo sapiens_hsa05152 | 2.22807109 |
| 10 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.20761186 |
| 11 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.17384926 |
| 12 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.05825804 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.04613041 |
| 14 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.03471063 |
| 15 | Malaria_Homo sapiens_hsa05144 | 1.96969983 |
| 16 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.87420072 |
| 17 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.82960492 |
| 18 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.80153734 |
| 19 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.78371717 |
| 20 | Measles_Homo sapiens_hsa05162 | 1.77292856 |
| 21 | Asthma_Homo sapiens_hsa05310 | 1.73275924 |
| 22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.71765648 |
| 23 | Viral myocarditis_Homo sapiens_hsa05416 | 1.70805425 |
| 24 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.67412607 |
| 25 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.60432388 |
| 26 | Influenza A_Homo sapiens_hsa05164 | 1.60383773 |
| 27 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.60341158 |
| 28 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.57694106 |
| 29 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.55349473 |
| 30 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.53186426 |
| 31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.51873711 |
| 32 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.51151219 |
| 33 | Legionellosis_Homo sapiens_hsa05134 | 1.48627239 |
| 34 | Phagosome_Homo sapiens_hsa04145 | 1.45174377 |
| 35 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.44956945 |
| 36 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.36367375 |
| 37 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.31999088 |
| 38 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.31040147 |
| 39 | Other glycan degradation_Homo sapiens_hsa00511 | 1.25188154 |
| 40 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.24255683 |
| 41 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.15024214 |
| 42 | Hepatitis B_Homo sapiens_hsa05161 | 1.12738120 |
| 43 | Hepatitis C_Homo sapiens_hsa05160 | 1.11062676 |
| 44 | Pertussis_Homo sapiens_hsa05133 | 1.08455187 |
| 45 | Salmonella infection_Homo sapiens_hsa05132 | 1.03528026 |
| 46 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.00773578 |
| 47 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.00421941 |
| 48 | Shigellosis_Homo sapiens_hsa05131 | 1.00316681 |
| 49 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.99210785 |
| 50 | Platelet activation_Homo sapiens_hsa04611 | 0.97804654 |
| 51 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.94778782 |
| 52 | Apoptosis_Homo sapiens_hsa04210 | 0.91787545 |
| 53 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.85765373 |
| 54 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.83629177 |
| 55 | Lysosome_Homo sapiens_hsa04142 | 0.82570308 |
| 56 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.82407836 |
| 57 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.79583474 |
| 58 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.78937791 |
| 59 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.77350761 |
| 60 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.72994652 |
| 61 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.71091459 |
| 62 | Endocytosis_Homo sapiens_hsa04144 | 0.70952590 |
| 63 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.68071900 |
| 64 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.66460240 |
| 65 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.66386011 |
| 66 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.65818703 |
| 67 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.64735423 |
| 68 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.60691971 |
| 69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.60144261 |
| 70 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.58057361 |
| 71 | HTLV-I infection_Homo sapiens_hsa05166 | 0.57684396 |
| 72 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.57242412 |
| 73 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.57218882 |
| 74 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.55839271 |
| 75 | Amoebiasis_Homo sapiens_hsa05146 | 0.53924939 |
| 76 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.48596648 |
| 77 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.48465356 |
| 78 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.47895012 |
| 79 | Endometrial cancer_Homo sapiens_hsa05213 | 0.46302345 |
| 80 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.45629606 |
| 81 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.45549609 |
| 82 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.44930871 |
| 83 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.44674284 |
| 84 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.43042567 |
| 85 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.42496934 |
| 86 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.42355094 |
| 87 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.41919423 |
| 88 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.40171090 |
| 89 | Insulin resistance_Homo sapiens_hsa04931 | 0.39951609 |
| 90 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.38058616 |
| 91 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.37967088 |
| 92 | Colorectal cancer_Homo sapiens_hsa05210 | 0.37930088 |
| 93 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.37239209 |
| 94 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.35098453 |
| 95 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.34853191 |
| 96 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.34581393 |
| 97 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.32745230 |
| 98 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.32512188 |
| 99 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.27151794 |
| 100 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.25315692 |

