NCKAP5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1presynaptic membrane assembly (GO:0097105)5.75781477
2pyrimidine nucleobase catabolic process (GO:0006208)5.10629545
3presynaptic membrane organization (GO:0097090)4.74875549
4postsynaptic membrane organization (GO:0001941)4.65794545
5limb bud formation (GO:0060174)4.30244848
6nucleobase catabolic process (GO:0046113)4.03052042
7cerebral cortex radially oriented cell migration (GO:0021799)3.95365958
8neuron cell-cell adhesion (GO:0007158)3.95197117
9axon ensheathment in central nervous system (GO:0032291)3.94725453
10central nervous system myelination (GO:0022010)3.94725453
11photoreceptor cell differentiation (GO:0046530)3.81177341
12eye photoreceptor cell differentiation (GO:0001754)3.81177341
13behavioral response to nicotine (GO:0035095)3.76821026
14retinal rod cell development (GO:0046548)3.75059609
15response to redox state (GO:0051775)3.72476318
16transmission of nerve impulse (GO:0019226)3.72362147
17nonmotile primary cilium assembly (GO:0035058)3.48714190
18myelination (GO:0042552)3.47596212
19epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.42360361
20L-amino acid import (GO:0043092)3.41516622
21camera-type eye morphogenesis (GO:0048593)3.38606322
22regulation of glutamate receptor signaling pathway (GO:1900449)3.38096705
23negative regulation of neurotransmitter secretion (GO:0046929)3.36295590
24axon ensheathment (GO:0008366)3.36216274
25ensheathment of neurons (GO:0007272)3.36216274
26peripheral nervous system axon ensheathment (GO:0032292)3.33770393
27myelination in peripheral nervous system (GO:0022011)3.33770393
28synaptic transmission, glutamatergic (GO:0035249)3.30775034
29startle response (GO:0001964)3.28657289
30cellular response to epinephrine stimulus (GO:0071872)3.24481979
31response to epinephrine (GO:0071871)3.22609295
32central nervous system neuron axonogenesis (GO:0021955)3.22506124
33oligodendrocyte differentiation (GO:0048709)3.18593607
34membrane assembly (GO:0071709)3.09563376
35regulation of collateral sprouting (GO:0048670)3.06758382
36spinal cord development (GO:0021510)3.05537790
37negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.03977967
38negative regulation of translation, ncRNA-mediated (GO:0040033)3.03977967
39regulation of translation, ncRNA-mediated (GO:0045974)3.03977967
40axon extension (GO:0048675)3.03207187
41negative regulation of myoblast differentiation (GO:0045662)3.01427317
42nucleotide transmembrane transport (GO:1901679)3.00992692
43establishment of mitochondrion localization (GO:0051654)2.96025169
44G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.94540659
45artery development (GO:0060840)2.94454615
46cellular response to hepatocyte growth factor stimulus (GO:0035729)2.91103058
47response to hepatocyte growth factor (GO:0035728)2.91103058
48dendritic spine morphogenesis (GO:0060997)2.90923431
49regulation of phospholipid biosynthetic process (GO:0071071)2.90727336
50appendage development (GO:0048736)2.89677865
51limb development (GO:0060173)2.89677865
52neurotransmitter-gated ion channel clustering (GO:0072578)2.87027788
53retinal cone cell development (GO:0046549)2.86712556
54positive regulation of action potential (GO:0045760)2.86548292
55neuron fate determination (GO:0048664)2.86242984
56virion attachment to host cell (GO:0019062)2.84973524
57adhesion of symbiont to host cell (GO:0044650)2.84973524
58positive regulation of meiosis (GO:0045836)2.83993345
59lateral sprouting from an epithelium (GO:0060601)2.83543483
60amino acid import (GO:0043090)2.83493937
61negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.82920645
62pattern specification involved in kidney development (GO:0061004)2.81036987
63forebrain neuron development (GO:0021884)2.81012337
64neuronal ion channel clustering (GO:0045161)2.80658064
65glycerophospholipid catabolic process (GO:0046475)2.80442037
66positive regulation of vascular permeability (GO:0043117)2.80426808
67neuronal stem cell maintenance (GO:0097150)2.79024873
68righting reflex (GO:0060013)2.78156738
69ganglion development (GO:0061548)2.78047554
70fatty acid elongation (GO:0030497)2.76535361
71retina layer formation (GO:0010842)2.76237932
72photoreceptor cell development (GO:0042461)2.76220907
73surfactant homeostasis (GO:0043129)2.76067193
74calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.74494307
75negative regulation of axon extension (GO:0030517)2.70563336
76positive regulation of meiotic cell cycle (GO:0051446)2.70474562
77neuron projection extension involved in neuron projection guidance (GO:1902284)2.69858116
78axon extension involved in axon guidance (GO:0048846)2.69858116
79cerebellar granule cell differentiation (GO:0021707)2.67940124
80establishment of planar polarity (GO:0001736)2.67622319
81establishment of tissue polarity (GO:0007164)2.67622319
82regulation of timing of cell differentiation (GO:0048505)2.67427391
83protein prenylation (GO:0018342)2.66594822
84prenylation (GO:0097354)2.66594822
85dendrite morphogenesis (GO:0048813)2.66285370
86response to auditory stimulus (GO:0010996)2.64485864
87neuron recognition (GO:0008038)2.64148061
88hindbrain development (GO:0030902)2.63431729
89long-chain fatty acid biosynthetic process (GO:0042759)2.62985160
90cranial nerve morphogenesis (GO:0021602)2.62555414
91neuron-neuron synaptic transmission (GO:0007270)2.62299220
92negative regulation of systemic arterial blood pressure (GO:0003085)2.61055095
93synaptic transmission, cholinergic (GO:0007271)2.60968575
94axonal fasciculation (GO:0007413)2.60496717
95establishment of nucleus localization (GO:0040023)2.59637818
96adult walking behavior (GO:0007628)2.58772485
97negative regulation of neurotransmitter transport (GO:0051589)2.58593591
98lens morphogenesis in camera-type eye (GO:0002089)2.58424757
99negative regulation of axon extension involved in axon guidance (GO:0048843)2.57828352
100cranial nerve development (GO:0021545)2.57745376
101head development (GO:0060322)2.57454897
102epithelial cilium movement (GO:0003351)2.57348704
103exploration behavior (GO:0035640)2.57166821
104import into cell (GO:0098657)2.56788247
105telencephalon cell migration (GO:0022029)2.56585167
106forebrain cell migration (GO:0021885)2.56399001
107semaphorin-plexin signaling pathway (GO:0071526)2.56005794
108intraciliary transport (GO:0042073)2.54535441
109retinal ganglion cell axon guidance (GO:0031290)2.53185693
110regulation of somitogenesis (GO:0014807)2.52612189
111mechanosensory behavior (GO:0007638)2.51856792
112regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.51178874
113chemical homeostasis within a tissue (GO:0048875)2.49971784
114neuron projection extension (GO:1990138)2.47271669
115positive regulation of neurological system process (GO:0031646)2.47095727
116synapse assembly (GO:0007416)2.47055268
117glutamate receptor signaling pathway (GO:0007215)2.46651282
118regulation of axon extension involved in axon guidance (GO:0048841)2.46384758
119eye photoreceptor cell development (GO:0042462)2.46196163
120locomotory exploration behavior (GO:0035641)2.45770730
121positive regulation of synapse assembly (GO:0051965)2.45666665
122negative regulation of axon guidance (GO:1902668)2.45634656
123synaptic vesicle endocytosis (GO:0048488)2.44889815
124response to monoamine (GO:0071867)2.44539930
125response to catecholamine (GO:0071869)2.44539930
126somite development (GO:0061053)2.44525868
127mechanoreceptor differentiation (GO:0042490)2.43782948
128protein localization to synapse (GO:0035418)2.43155309
129regulation of short-term neuronal synaptic plasticity (GO:0048172)2.42798641
130tongue development (GO:0043586)2.42407200
131negative regulation of protein localization to cell surface (GO:2000009)2.42376240
132cell proliferation in forebrain (GO:0021846)2.41508701
133cell migration in hindbrain (GO:0021535)2.41340104
134regulation of axon guidance (GO:1902667)2.39841024
135detection of light stimulus involved in sensory perception (GO:0050962)2.39685848
136detection of light stimulus involved in visual perception (GO:0050908)2.39685848
137cellular response to catecholamine stimulus (GO:0071870)2.38685923
138cellular response to monoamine stimulus (GO:0071868)2.38685923
139photoreceptor cell maintenance (GO:0045494)2.37940953
140reflex (GO:0060004)2.37517869
141spinal cord motor neuron differentiation (GO:0021522)2.37471162
142female gonad development (GO:0008585)2.37235811
143axoneme assembly (GO:0035082)2.36802392
144adenine nucleotide transport (GO:0051503)2.36724867
145vocalization behavior (GO:0071625)2.35159909
146inner ear receptor stereocilium organization (GO:0060122)2.34558683
147regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.34111462
148specification of organ identity (GO:0010092)2.33810102
149negative regulation of axonogenesis (GO:0050771)2.33324268
150central nervous system projection neuron axonogenesis (GO:0021952)2.33270425
151C4-dicarboxylate transport (GO:0015740)2.33190256
152auditory behavior (GO:0031223)2.32748264
153adhesion of symbiont to host (GO:0044406)2.32593854
154neuron migration (GO:0001764)2.32297260
155auditory receptor cell differentiation (GO:0042491)2.32002894
156regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.31545993
157cerebral cortex cell migration (GO:0021795)2.31417986
158apical protein localization (GO:0045176)2.31373906
159positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.31246318
160gamma-aminobutyric acid signaling pathway (GO:0007214)2.30404481
161ionotropic glutamate receptor signaling pathway (GO:0035235)2.30080338
162kidney morphogenesis (GO:0060993)2.29880534
163Rap protein signal transduction (GO:0032486)2.28683774
164negative regulation of astrocyte differentiation (GO:0048712)2.27861853
165otic vesicle formation (GO:0030916)2.26937237

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.82559286
2RBPJ_22232070_ChIP-Seq_NCS_Mouse3.19367671
3EZH2_22144423_ChIP-Seq_EOC_Human2.92520536
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.31273993
5* ZFP57_27257070_Chip-Seq_ESCs_Mouse2.30371343
6GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.29390846
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.28459187
8NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.25867977
9SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.22104115
10EED_16625203_ChIP-ChIP_MESCs_Mouse2.18639693
11SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.17022936
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.07716364
13AR_21572438_ChIP-Seq_LNCaP_Human2.06343816
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.04242096
15CBX2_27304074_Chip-Seq_ESCs_Mouse1.97366402
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.93983803
17PIAS1_25552417_ChIP-Seq_VCAP_Human1.91474664
18RNF2_18974828_ChIP-Seq_MESCs_Mouse1.88522639
19EZH2_18974828_ChIP-Seq_MESCs_Mouse1.88522639
20JARID2_20075857_ChIP-Seq_MESCs_Mouse1.86950105
21PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.86531407
22TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.80860189
23TAF15_26573619_Chip-Seq_HEK293_Human1.80307950
24SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.79934139
25POU3F2_20337985_ChIP-ChIP_501MEL_Human1.78829293
26DROSHA_22980978_ChIP-Seq_HELA_Human1.78561838
27* EZH2_27294783_Chip-Seq_ESCs_Mouse1.77477275
28CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.75189986
29CDX2_19796622_ChIP-Seq_MESCs_Mouse1.72977219
30RNF2_27304074_Chip-Seq_ESCs_Mouse1.72339988
31BMI1_23680149_ChIP-Seq_NPCS_Mouse1.70655468
32MTF2_20144788_ChIP-Seq_MESCs_Mouse1.69791998
33* P300_19829295_ChIP-Seq_ESCs_Human1.69249248
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.68462208
35SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.66627425
36* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.65968590
37SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.64303153
38PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.62718966
39FUS_26573619_Chip-Seq_HEK293_Human1.62649917
40ZNF217_24962896_ChIP-Seq_MCF-7_Human1.61805209
41* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.61671938
42CTBP1_25329375_ChIP-Seq_LNCAP_Human1.59300408
43* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.59229584
44* SMAD4_21799915_ChIP-Seq_A2780_Human1.58796905
45RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.58584523
46TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.58396135
47POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.58396135
48* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.54550339
49SMAD3_21741376_ChIP-Seq_EPCs_Human1.54421545
50* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.52881674
51* NANOG_18555785_Chip-Seq_ESCs_Mouse1.52805864
52OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.51771592
53RNF2_27304074_Chip-Seq_NSC_Mouse1.51325207
54FLI1_27457419_Chip-Seq_LIVER_Mouse1.50911371
55* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.46863156
56ER_23166858_ChIP-Seq_MCF-7_Human1.44810189
57AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.42795919
58* E2F1_18555785_Chip-Seq_ESCs_Mouse1.42032478
59EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.40382859
60* PCGF2_27294783_Chip-Seq_NPCs_Mouse1.39998534
61ZNF274_21170338_ChIP-Seq_K562_Hela1.39356303
62SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39304352
63MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.34972086
64STAT3_23295773_ChIP-Seq_U87_Human1.34744443
65* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.34617203
66* P53_22387025_ChIP-Seq_ESCs_Mouse1.34353458
67TP53_16413492_ChIP-PET_HCT116_Human1.33712129
68* NFE2_27457419_Chip-Seq_LIVER_Mouse1.33305737
69* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32078819
70* ARNT_22903824_ChIP-Seq_MCF-7_Human1.31988436
71BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.30725500
72* AHR_22903824_ChIP-Seq_MCF-7_Human1.30315621
73STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.30207514
74* CMYC_18555785_Chip-Seq_ESCs_Mouse1.29520512
75VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.28832172
76BCAT_22108803_ChIP-Seq_LS180_Human1.27815778
77TCF4_23295773_ChIP-Seq_U87_Human1.25919709
78EWS_26573619_Chip-Seq_HEK293_Human1.25150293
79* EZH2_27294783_Chip-Seq_NPCs_Mouse1.24608556
80YAP1_20516196_ChIP-Seq_MESCs_Mouse1.23996490
81* REST_21632747_ChIP-Seq_MESCs_Mouse1.22929083
82TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22226242
83* CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21496590
84* P300_18555785_Chip-Seq_ESCs_Mouse1.21434260
85RUNX2_22187159_ChIP-Seq_PCA_Human1.20887433
86* STAT3_18555785_Chip-Seq_ESCs_Mouse1.20544013
87TRIM28_21343339_ChIP-Seq_HEK293_Human1.20302658
88* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.19036867
89REST_18959480_ChIP-ChIP_MESCs_Mouse1.18338610
90NR3C1_21868756_ChIP-Seq_MCF10A_Human1.17753581
91* NMYC_18555785_Chip-Seq_ESCs_Mouse1.16829161
92TP53_18474530_ChIP-ChIP_U2OS_Human1.16792541
93AR_25329375_ChIP-Seq_VCAP_Human1.16757959
94RING1B_27294783_Chip-Seq_ESCs_Mouse1.16547272
95CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.16505503
96TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16119055
97EP300_21415370_ChIP-Seq_HL-1_Mouse1.15632202
98UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.15615102
99* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.14284235
100SALL1_21062744_ChIP-ChIP_HESCs_Human1.13680149
101RING1B_27294783_Chip-Seq_NPCs_Mouse1.12808311
102* TAL1_26923725_Chip-Seq_HPCs_Mouse1.12318037
103P53_22127205_ChIP-Seq_FIBROBLAST_Human1.11979219
104CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.11905137
105HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.11896199
106SMAD_19615063_ChIP-ChIP_OVARY_Human1.11885931
107* SOX2_18555785_Chip-Seq_ESCs_Mouse1.11478291
108MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.11431888
109OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.11290051
110* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.10972909
111SOX2_21211035_ChIP-Seq_LN229_Gbm1.10490397
112* TCF4_22108803_ChIP-Seq_LS180_Human1.09506609
113* KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.09408768
114* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.07826618
115* OCT4_18555785_Chip-Seq_ESCs_Mouse1.07659004
116MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06961849
117VDR_22108803_ChIP-Seq_LS180_Human1.06624820
118SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.06385712
119AR_19668381_ChIP-Seq_PC3_Human1.05259273
120CBP_20019798_ChIP-Seq_JUKART_Human1.05054208
121IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.05054208
122SMAD3_21741376_ChIP-Seq_ESCs_Human1.04236159
123ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.04235893
124* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03881799
125* ZFX_18555785_Chip-Seq_ESCs_Mouse1.03740319
126ISL1_27105846_Chip-Seq_CPCs_Mouse1.03153895
127* KLF4_18555785_Chip-Seq_ESCs_Mouse1.03054867
128NR3C1_23031785_ChIP-Seq_PC12_Mouse1.01719541

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000566_synostosis4.04840881
2MP0005171_absent_coat_pigmentation2.85295553
3MP0003880_abnormal_central_pattern2.77742412
4MP0002102_abnormal_ear_morphology2.74435966
5MP0001188_hyperpigmentation2.50173835
6MP0001486_abnormal_startle_reflex2.49485488
7MP0006292_abnormal_olfactory_placode2.38044421
8MP0004742_abnormal_vestibular_system2.34207099
9MP0000778_abnormal_nervous_system2.30554543
10MP0003136_yellow_coat_color2.27801299
11MP0005551_abnormal_eye_electrophysiolog2.23811699
12MP0001177_atelectasis2.09567150
13MP0000462_abnormal_digestive_system2.04198509
14MP0001485_abnormal_pinna_reflex2.02662996
15MP0008789_abnormal_olfactory_epithelium1.97768613
16MP0003122_maternal_imprinting1.95604613
17MP0000579_abnormal_nail_morphology1.91355675
18MP0005409_darkened_coat_color1.89193287
19MP0006072_abnormal_retinal_apoptosis1.85748880
20MP0008995_early_reproductive_senescence1.84410875
21MP0000026_abnormal_inner_ear1.82963039
22MP0000383_abnormal_hair_follicle1.80237443
23MP0001346_abnormal_lacrimal_gland1.76565477
24MP0005499_abnormal_olfactory_system1.73510310
25MP0005394_taste/olfaction_phenotype1.73510310
26MP0010030_abnormal_orbit_morphology1.71458300
27MP0001963_abnormal_hearing_physiology1.70516896
28MP0004885_abnormal_endolymph1.66902681
29MP0005646_abnormal_pituitary_gland1.61754460
30MP0004782_abnormal_surfactant_physiolog1.59158864
31MP0003690_abnormal_glial_cell1.58341132
32MP0005253_abnormal_eye_physiology1.56757161
33MP0002272_abnormal_nervous_system1.56359919
34MP0004859_abnormal_synaptic_plasticity1.54069888
35MP0001502_abnormal_circadian_rhythm1.53678218
36MP0003787_abnormal_imprinting1.52402675
37MP0003121_genomic_imprinting1.52112528
38MP0000920_abnormal_myelination1.47506641
39MP0002572_abnormal_emotion/affect_behav1.43785259
40MP0003937_abnormal_limbs/digits/tail_de1.43101768
41MP0001440_abnormal_grooming_behavior1.43067777
42MP0002736_abnormal_nociception_after1.42278628
43MP0000631_abnormal_neuroendocrine_gland1.41806914
44MP0003635_abnormal_synaptic_transmissio1.39748848
45MP0001984_abnormal_olfaction1.39440421
46MP0005187_abnormal_penis_morphology1.39361612
47MP0001970_abnormal_pain_threshold1.39189067
48MP0009745_abnormal_behavioral_response1.39153448
49MP0009384_cardiac_valve_regurgitation1.38240660
50MP0002733_abnormal_thermal_nociception1.38062026
51MP0002752_abnormal_somatic_nervous1.34167159
52MP0002064_seizures1.32475068
53MP0005248_abnormal_Harderian_gland1.32248465
54MP0002067_abnormal_sensory_capabilities1.31717537
55MP0002277_abnormal_respiratory_mucosa1.28808860
56MP0001968_abnormal_touch/_nociception1.28665125
57MP0005377_hearing/vestibular/ear_phenot1.27802164
58MP0003878_abnormal_ear_physiology1.27802164
59MP0009053_abnormal_anal_canal1.26658789
60MP0008004_abnormal_stomach_pH1.25539785
61MP0002557_abnormal_social/conspecific_i1.24946757
62MP0001879_abnormal_lymphatic_vessel1.23567240
63MP0005195_abnormal_posterior_eye1.22823404
64MP0003950_abnormal_plasma_membrane1.21849252
65MP0009250_abnormal_appendicular_skeleto1.21844847
66MP0000534_abnormal_ureter_morphology1.21431759
67MP0003938_abnormal_ear_development1.19306740
68MP0002063_abnormal_learning/memory/cond1.18874638
69MP0002184_abnormal_innervation1.18516979
70MP0002882_abnormal_neuron_morphology1.18495900
71MP0001501_abnormal_sleep_pattern1.18331937
72MP0004133_heterotaxia1.17455087
73MP0003942_abnormal_urinary_system1.16992211
74MP0002938_white_spotting1.16698587
75MP0004381_abnormal_hair_follicle1.16193797
76MP0002638_abnormal_pupillary_reflex1.15748391
77MP0003879_abnormal_hair_cell1.15236123
78MP0004134_abnormal_chest_morphology1.15152743
79MP0004270_analgesia1.14979344
80MP0009780_abnormal_chondrocyte_physiolo1.14046323
81MP0001905_abnormal_dopamine_level1.13394922
82MP0001529_abnormal_vocalization1.12775535
83MP0002653_abnormal_ependyma_morphology1.12436778
84MP0002133_abnormal_respiratory_system1.11952808
85MP0005388_respiratory_system_phenotype1.11952808
86MP0002234_abnormal_pharynx_morphology1.11095938
87MP0002295_abnormal_pulmonary_circulatio1.10322274
88MP0000762_abnormal_tongue_morphology1.10267380
89MP0002152_abnormal_brain_morphology1.08299199
90MP0001293_anophthalmia1.07701143
91MP0002233_abnormal_nose_morphology1.07260242
92MP0002735_abnormal_chemical_nociception1.06883407
93MP0010368_abnormal_lymphatic_system1.03725908
94MP0005367_renal/urinary_system_phenotyp1.03466219
95MP0000516_abnormal_urinary_system1.03466219
96MP0003634_abnormal_glial_cell1.03266100
97MP0010678_abnormal_skin_adnexa1.03253229
98MP0009046_muscle_twitch1.02329956
99MP0005423_abnormal_somatic_nervous1.02271485
100MP0005257_abnormal_intraocular_pressure1.01557300
101MP0002697_abnormal_eye_size1.00744027
102MP0003890_abnormal_embryonic-extraembry1.00520989
103MP0001986_abnormal_taste_sensitivity1.00174823
104MP0003119_abnormal_digestive_system0.98949403
105MP0005174_abnormal_tail_pigmentation0.98075529
106MP0003941_abnormal_skin_development0.97895299
107MP0001299_abnormal_eye_distance/0.97869542
108MP0003385_abnormal_body_wall0.97782789
109MP0000049_abnormal_middle_ear0.97524418
110MP0002282_abnormal_trachea_morphology0.97308972
111MP0001324_abnormal_eye_pigmentation0.97270300
112MP0002734_abnormal_mechanical_nocicepti0.97155039
113MP0009379_abnormal_foot_pigmentation0.97131831
114MP0002090_abnormal_vision0.97131147
115MP0002928_abnormal_bile_duct0.96774916
116MP0000569_abnormal_digit_pigmentation0.95975208
117MP0005645_abnormal_hypothalamus_physiol0.94713296
118MP0002098_abnormal_vibrissa_morphology0.93242654
119MP0000538_abnormal_urinary_bladder0.92600190
120MP0003861_abnormal_nervous_system0.92226093
121MP0005503_abnormal_tendon_morphology0.90907286
122MP0001286_abnormal_eye_development0.90713213
123MP0006276_abnormal_autonomic_nervous0.90201498
124MP0002229_neurodegeneration0.89762443
125MP0004142_abnormal_muscle_tone0.89307596
126MP0002249_abnormal_larynx_morphology0.87261788
127MP0002876_abnormal_thyroid_physiology0.84810608
128MP0004924_abnormal_behavior0.82741278
129MP0005386_behavior/neurological_phenoty0.82741278
130MP0004272_abnormal_basement_membrane0.82551402
131MP0010386_abnormal_urinary_bladder0.81951306
132MP0000955_abnormal_spinal_cord0.80597592
133MP0003755_abnormal_palate_morphology0.76666970

Predicted human phenotypes

RankGene SetZ-score
1Split foot (HP:0001839)3.82580176
2Congenital sensorineural hearing impairment (HP:0008527)3.48885696
3Aplasia involving bones of the upper limbs (HP:0009823)3.45619788
4Aplasia of the phalanges of the hand (HP:0009802)3.45619788
5Aplasia involving bones of the extremities (HP:0009825)3.45619788
6Abnormality of the labia minora (HP:0012880)3.41698293
7Tubulointerstitial nephritis (HP:0001970)3.17962535
8Abnormality of incisor morphology (HP:0011063)3.16569630
9Mixed hearing impairment (HP:0000410)3.06602897
10Sensory axonal neuropathy (HP:0003390)3.05552946
11Hepatoblastoma (HP:0002884)3.03043283
12Febrile seizures (HP:0002373)2.99453561
13Alacrima (HP:0000522)2.96125533
14Septo-optic dysplasia (HP:0100842)2.94287546
15Anomalous pulmonary venous return (HP:0010772)2.90096075
16Cupped ear (HP:0000378)2.83315108
17Congenital stationary night blindness (HP:0007642)2.81636391
18Abnormality of the pulmonary veins (HP:0011718)2.81397626
19Gait imbalance (HP:0002141)2.80577115
20Decreased lacrimation (HP:0000633)2.79292424
21Parakeratosis (HP:0001036)2.76371523
22Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.76282485
23Short 4th metacarpal (HP:0010044)2.76282485
24Entropion (HP:0000621)2.70825657
25Growth hormone deficiency (HP:0000824)2.64490408
26Focal seizures (HP:0007359)2.62670535
27Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.61691445
28Megalencephaly (HP:0001355)2.61435326
29Humeroradial synostosis (HP:0003041)2.57260668
30Synostosis involving the elbow (HP:0003938)2.57260668
31Oligodactyly (hands) (HP:0001180)2.56413184
32Myokymia (HP:0002411)2.55619314
33Decreased central vision (HP:0007663)2.53852444
34Medial flaring of the eyebrow (HP:0010747)2.50123189
35Atonic seizures (HP:0010819)2.49884123
36Abnormality of DNA repair (HP:0003254)2.47150063
37Pancreatic fibrosis (HP:0100732)2.46096379
38Abnormal ciliary motility (HP:0012262)2.43266419
39Cutaneous finger syndactyly (HP:0010554)2.42468676
40Abnormality of macular pigmentation (HP:0008002)2.41487482
41Polyphagia (HP:0002591)2.39548980
42Congenital primary aphakia (HP:0007707)2.36662640
43Thyroid-stimulating hormone excess (HP:0002925)2.35611190
44Conical tooth (HP:0000698)2.29279358
45Hemiparesis (HP:0001269)2.28906606
46Abnormality of the diencephalon (HP:0010662)2.28294898
47Abnormality of the 4th metacarpal (HP:0010012)2.27077594
48Abnormality of the lacrimal duct (HP:0011481)2.26862589
49Thickened helices (HP:0000391)2.25579076
50Optic nerve hypoplasia (HP:0000609)2.25066025
51Aplasia/Hypoplasia of the fovea (HP:0008060)2.24960705
52Hypoplasia of the fovea (HP:0007750)2.24960705
53Abnormal respiratory motile cilium physiology (HP:0012261)2.23690820
54Hypoplasia of the ulna (HP:0003022)2.23422629
55Midline defect of the nose (HP:0004122)2.23215137
56Chronic hepatic failure (HP:0100626)2.23071792
57Aplasia cutis congenita (HP:0001057)2.21926284
58Partial duplication of thumb phalanx (HP:0009944)2.21865390
59Abnormality of the nasolacrimal system (HP:0000614)2.19858483
60Poikiloderma (HP:0001029)2.19397438
61Anophthalmia (HP:0000528)2.18941706
62Pachygyria (HP:0001302)2.16625491
63Abnormality of the parathyroid morphology (HP:0011766)2.16575150
64Nephrogenic diabetes insipidus (HP:0009806)2.15491042
65Abnormality of the renal medulla (HP:0100957)2.14008700
66Degeneration of the lateral corticospinal tracts (HP:0002314)2.13600621
67Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.13600621
68White forelock (HP:0002211)2.13576665
69Pancreatic cysts (HP:0001737)2.12607110
70Nephronophthisis (HP:0000090)2.12266333
71Nasolacrimal duct obstruction (HP:0000579)2.11191854
72Rib fusion (HP:0000902)2.10920457
73Absent septum pellucidum (HP:0001331)2.10780571
74Adrenal hypoplasia (HP:0000835)2.10730632
75Overgrowth (HP:0001548)2.09014038
76Bell-shaped thorax (HP:0001591)2.08538274
77Cutaneous syndactyly (HP:0012725)2.08516428
78Absent/shortened dynein arms (HP:0200106)2.07537224
79Dynein arm defect of respiratory motile cilia (HP:0012255)2.07537224
80Labial hypoplasia (HP:0000066)2.06698078
81Abnormality of the ischium (HP:0003174)2.06105610
82Abnormality of the fovea (HP:0000493)2.04663959
83Aplasia/Hypoplasia of the ulna (HP:0006495)2.04369772
84Hyperventilation (HP:0002883)2.03761112
85Renal hypoplasia (HP:0000089)2.03600626
86Broad-based gait (HP:0002136)2.02599986
87Focal motor seizures (HP:0011153)2.02550976
88Postaxial hand polydactyly (HP:0001162)2.00727218
89Turricephaly (HP:0000262)2.00687324
90Patchy hypopigmentation of hair (HP:0011365)2.00065591
91Hypoplastic nipples (HP:0002557)1.99751983
92Xerostomia (HP:0000217)1.99255648
93Oligodactyly (HP:0012165)1.99124960
94Renal dysplasia (HP:0000110)1.98046685
95Action tremor (HP:0002345)1.97881620
96Aplasia/Hypoplasia of the tongue (HP:0010295)1.97527711
97Esophageal atresia (HP:0002032)1.96707839
98Lissencephaly (HP:0001339)1.95008907
99Drooling (HP:0002307)1.94463580
100Neonatal short-limb short stature (HP:0008921)1.94434285
101Fetal akinesia sequence (HP:0001989)1.93090389
102Myelomeningocele (HP:0002475)1.92915791
103True hermaphroditism (HP:0010459)1.92856559
104Hip dysplasia (HP:0001385)1.92598424
105Preaxial hand polydactyly (HP:0001177)1.91431793
106Adactyly (HP:0009776)1.91085590
107Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.90897440
108Duplication of thumb phalanx (HP:0009942)1.89764985
109Akinesia (HP:0002304)1.86979341
110Bifid tongue (HP:0010297)1.86544566
111Meningocele (HP:0002435)1.86352588
112Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.85528489
113Genetic anticipation (HP:0003743)1.85477655
114Epileptic encephalopathy (HP:0200134)1.85073852
115Abnormality of the septum pellucidum (HP:0007375)1.85002538
116Renal agenesis (HP:0000104)1.80725032
117Poor coordination (HP:0002370)1.79886920
118Atelectasis (HP:0100750)1.79535048
119Shawl scrotum (HP:0000049)1.78558692
120Coronal craniosynostosis (HP:0004440)1.78385384
121Maternal diabetes (HP:0009800)1.78323276
122Vaginal atresia (HP:0000148)1.77804483
123Hyperkalemia (HP:0002153)1.77584561
124Postaxial foot polydactyly (HP:0001830)1.76983608
125Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.76940247
126Hypoplastic female external genitalia (HP:0012815)1.76536979
127Specific learning disability (HP:0001328)1.76526041
128Abnormality of midbrain morphology (HP:0002418)1.76298612
129Molar tooth sign on MRI (HP:0002419)1.76298612
130Supernumerary spleens (HP:0009799)1.76275517
131Abnormality of the metopic suture (HP:0005556)1.76164547
132Stenosis of the external auditory canal (HP:0000402)1.75963899
133Intellectual disability, moderate (HP:0002342)1.75643949
134Genital tract atresia (HP:0001827)1.75635981
135Long nose (HP:0003189)1.75330595
136Central scotoma (HP:0000603)1.75133519
137Cone-rod dystrophy (HP:0000548)1.75038302
138Down-sloping shoulders (HP:0200021)1.74589725
139Abnormality of molar (HP:0011077)1.74573314
140Abnormality of molar morphology (HP:0011070)1.74573314
141Abnormality of the dental pulp (HP:0006479)1.74328709
142Hypoplastic pelvis (HP:0008839)1.74227115
143Narrow forehead (HP:0000341)1.74167870
144Intestinal atresia (HP:0011100)1.73149339
145Tubulointerstitial abnormality (HP:0001969)1.72738494
146Severe Myopia (HP:0011003)1.72686319
147Morphological abnormality of the middle ear (HP:0008609)1.72250239
148Hyperactive renin-angiotensin system (HP:0000841)1.72124308
149Keratoconus (HP:0000563)1.72096515
150Increased corneal curvature (HP:0100692)1.72096515
151Bifid scrotum (HP:0000048)1.71731653
152Tubular atrophy (HP:0000092)1.71355037
153Partial duplication of the phalanx of hand (HP:0009999)1.71125126
154Anencephaly (HP:0002323)1.70988470
155Overfolded helix (HP:0000396)1.70685682
156Hypoplastic ischia (HP:0003175)1.68401206
157Retinal dysplasia (HP:0007973)1.68091392
158Excessive salivation (HP:0003781)1.66037191
159Absent speech (HP:0001344)1.65134964
160Gastrointestinal atresia (HP:0002589)1.65044726
161Vitreoretinal degeneration (HP:0000655)1.64774725
162Type II lissencephaly (HP:0007260)1.63225818
163Micropenis (HP:0000054)1.62993763
164Epileptiform EEG discharges (HP:0011182)1.62973873
165Morphological abnormality of the inner ear (HP:0011390)1.62919848
166Fibular hypoplasia (HP:0003038)1.62717548
167Abnormality of the antihelix (HP:0009738)1.62096848
168EEG with generalized epileptiform discharges (HP:0011198)1.59353710

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK168.20086122
2TNIK6.27710164
3CASK4.29367408
4STK393.31543710
5PNCK2.58116098
6MAPK132.15047949
7PRPF4B2.15009472
8INSRR2.13989260
9NTRK32.13327739
10OXSR12.07846890
11BCR1.87491989
12IRAK21.85642859
13EPHA41.84962726
14PKN11.84626804
15WNK41.80561484
16EPHB11.74777144
17CDK31.58148834
18IRAK11.57876528
19NEK61.50640687
20MUSK1.48542274
21NTRK11.47338439
22GRK11.39561225
23MAP4K21.36519837
24AKT31.35340682
25NTRK21.34942455
26FRK1.34671141
27PDK21.28798665
28MARK11.25865517
29IRAK41.25643057
30FGFR21.23079315
31EPHB21.20000634
32BMPR1B1.17295675
33TGFBR11.12081253
34ICK1.07880341
35LATS11.07858422
36TIE11.03796220
37MKNK21.03676739
38SGK2231.02692444
39SGK4941.02692444
40NME11.02052615
41YES11.01892529
42WNK11.00792204
43EIF2AK21.00227563
44FGR1.00191909
45NLK0.99325194
46GRK70.99063787
47NUAK10.98064863
48PRKCE0.95863340
49MAP2K70.95058669
50MST40.92594786
51MAP3K40.90829446
52WEE10.90486950
53CAMK1G0.90187137
54FES0.89481443
55PHKG20.88739081
56PHKG10.88739081
57SIK20.85649187
58ERBB40.84462122
59MAP3K90.84404560
60ROCK10.84260107
61DDR20.82371176
62EPHA30.81615725
63SGK20.81182118
64MAP3K130.81143884
65CAMK2A0.80770713
66PAK60.80454094
67UHMK10.76877347
68PRKD30.76788395
69DYRK20.76051762
70ROCK20.72574863
71MAPK150.70867340
72BRSK20.70394473
73ADRBK20.68982603
74DYRK1A0.68326947
75ILK0.68236339
76MINK10.65827400
77DYRK1B0.65178328
78PRKCQ0.64928235
79RAF10.64722318
80SGK10.63466782
81BMPR20.63341616
82CAMK2B0.63181200
83PAK30.62870478
84PBK0.62840219
85STK240.60136675
86CAMK2D0.59827996
87BRD40.59662661
88IRAK30.58099525
89PINK10.57947860
90CAMK10.57832533
91LMTK20.57429686
92ZAK0.55539114
93PRKAA20.55373778
94CAMK1D0.55079323
95MET0.54823313
96PRKCZ0.54041426
97CDK190.53704780
98MAPK70.53386137
99STK38L0.52846876
100PRKG10.52215344
101CSNK1A1L0.51858421
102CSNK1E0.50701378
103CLK10.50129923
104MKNK10.49413926
105BCKDK0.49154679
106PRKACA0.48557036
107CDK80.47256325
108CDK50.46845039
109PLK20.46670546
110TYRO30.44980102
111ERBB20.43850048
112MARK20.43683992
113ADRBK10.40563696
114PDGFRB0.40200989
115PAK20.39884072
116CSNK1G20.39029602
117WNK30.38430614
118DMPK0.37531282
119PTK20.37418688
120PRKCG0.37019303
121PRKDC0.36073235
122MAPK140.36053535
123TXK0.35535971
124CSNK1D0.35007612
125RPS6KA30.34767784
126CSNK1G10.34688077
127ERBB30.34558045
128PRKACB0.34355403
129SRPK10.33845160
130SGK30.33371021
131CSNK1A10.33182382
132PIK3CA0.32080102
133MAP2K40.31527611
134CDK90.31463627
135GRK50.31314120
136GSK3B0.31222780
137FYN0.31197490
138CCNB10.30666446
139PRKD20.29980461
140CAMK2G0.29879998
141OBSCN0.28797015

Predicted pathways (KEGG)

RankGene SetZ-score
1Steroid biosynthesis_Homo sapiens_hsa001002.87755042
2Nicotine addiction_Homo sapiens_hsa050332.62270378
3Axon guidance_Homo sapiens_hsa043602.51632416
4Ether lipid metabolism_Homo sapiens_hsa005652.49977784
5Cell adhesion molecules (CAMs)_Homo sapiens_hsa045142.34928027
6Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.30710024
7Sphingolipid metabolism_Homo sapiens_hsa006001.96263393
8Glutamatergic synapse_Homo sapiens_hsa047241.91990721
9Serotonergic synapse_Homo sapiens_hsa047261.88038673
10Fatty acid elongation_Homo sapiens_hsa000621.82875830
11Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.78942842
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.76471375
13Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.76323913
14Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.66194556
15Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.66079880
16Taste transduction_Homo sapiens_hsa047421.63032153
17Morphine addiction_Homo sapiens_hsa050321.61067141
18Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.60744138
19Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.41290182
20GABAergic synapse_Homo sapiens_hsa047271.40772316
21Ovarian steroidogenesis_Homo sapiens_hsa049131.38982894
22Collecting duct acid secretion_Homo sapiens_hsa049661.36401923
23Notch signaling pathway_Homo sapiens_hsa043301.34560606
24Mineral absorption_Homo sapiens_hsa049781.30784084
25Circadian entrainment_Homo sapiens_hsa047131.30635486
26Phototransduction_Homo sapiens_hsa047441.30213566
27Rheumatoid arthritis_Homo sapiens_hsa053231.29566942
28Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.27520382
29Nucleotide excision repair_Homo sapiens_hsa034201.26752291
30Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.24263363
31ECM-receptor interaction_Homo sapiens_hsa045121.23598888
32Fatty acid biosynthesis_Homo sapiens_hsa000611.21080649
33Basal cell carcinoma_Homo sapiens_hsa052171.20746888
34Butanoate metabolism_Homo sapiens_hsa006501.19493071
35Salivary secretion_Homo sapiens_hsa049701.18919746
36Long-term depression_Homo sapiens_hsa047301.16322303
37Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.13184291
38Cholinergic synapse_Homo sapiens_hsa047251.10677311
39alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.09641066
40Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.08666937
41Cardiac muscle contraction_Homo sapiens_hsa042601.08591836
42Circadian rhythm_Homo sapiens_hsa047101.05551564
43Choline metabolism in cancer_Homo sapiens_hsa052311.02099858
44Renin secretion_Homo sapiens_hsa049241.01803060
45Steroid hormone biosynthesis_Homo sapiens_hsa001401.01652735
46Linoleic acid metabolism_Homo sapiens_hsa005911.00459301
47Insulin secretion_Homo sapiens_hsa049110.99915680
48Dorso-ventral axis formation_Homo sapiens_hsa043200.99888705
49Calcium signaling pathway_Homo sapiens_hsa040200.98641899
50Propanoate metabolism_Homo sapiens_hsa006400.96638692
51Protein export_Homo sapiens_hsa030600.93119893
52Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.90812197
53Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.89831829
54Ras signaling pathway_Homo sapiens_hsa040140.89807614
55Arachidonic acid metabolism_Homo sapiens_hsa005900.89088833
56Primary bile acid biosynthesis_Homo sapiens_hsa001200.88914485
57Autoimmune thyroid disease_Homo sapiens_hsa053200.88280739
58Nitrogen metabolism_Homo sapiens_hsa009100.86429357
59Estrogen signaling pathway_Homo sapiens_hsa049150.86065317
60Vitamin digestion and absorption_Homo sapiens_hsa049770.85879696
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.85479848
62cAMP signaling pathway_Homo sapiens_hsa040240.84178665
63Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.83590882
64Sulfur metabolism_Homo sapiens_hsa009200.83394913
65Vascular smooth muscle contraction_Homo sapiens_hsa042700.83038439
66Hedgehog signaling pathway_Homo sapiens_hsa043400.82337114
67Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.81293380
68Basal transcription factors_Homo sapiens_hsa030220.80968919
69Vibrio cholerae infection_Homo sapiens_hsa051100.80863051
70Aldosterone synthesis and secretion_Homo sapiens_hsa049250.80451364
71Tight junction_Homo sapiens_hsa045300.79672413
72Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.79223125
73Protein digestion and absorption_Homo sapiens_hsa049740.79121069
74Olfactory transduction_Homo sapiens_hsa047400.77946651
75Cocaine addiction_Homo sapiens_hsa050300.77189199
76Synaptic vesicle cycle_Homo sapiens_hsa047210.77004378
77Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.76937634
78Dilated cardiomyopathy_Homo sapiens_hsa054140.76539859
79Phosphatidylinositol signaling system_Homo sapiens_hsa040700.75503250
80Lysine degradation_Homo sapiens_hsa003100.75373037
81Renal cell carcinoma_Homo sapiens_hsa052110.75221809
82Bile secretion_Homo sapiens_hsa049760.74557422
83Dopaminergic synapse_Homo sapiens_hsa047280.74070071
84Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70570965
85GnRH signaling pathway_Homo sapiens_hsa049120.69559997
86Chemical carcinogenesis_Homo sapiens_hsa052040.68231268
87TGF-beta signaling pathway_Homo sapiens_hsa043500.68077624
88Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.67355440
89beta-Alanine metabolism_Homo sapiens_hsa004100.66715921
90Pancreatic secretion_Homo sapiens_hsa049720.66284196
91Amphetamine addiction_Homo sapiens_hsa050310.65558110
92Hippo signaling pathway_Homo sapiens_hsa043900.64618471
93Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.64127673
94Adherens junction_Homo sapiens_hsa045200.64080714
95Oxytocin signaling pathway_Homo sapiens_hsa049210.63764932
96ErbB signaling pathway_Homo sapiens_hsa040120.63404661
97Melanogenesis_Homo sapiens_hsa049160.63001303
98Glycerophospholipid metabolism_Homo sapiens_hsa005640.62854870
99Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.61594778
100Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.60610512
101Caffeine metabolism_Homo sapiens_hsa002320.60519336
102Gastric acid secretion_Homo sapiens_hsa049710.60311955
103Malaria_Homo sapiens_hsa051440.59997014
104Wnt signaling pathway_Homo sapiens_hsa043100.59927781
105Melanoma_Homo sapiens_hsa052180.59310306
106Endometrial cancer_Homo sapiens_hsa052130.59279104
107Fanconi anemia pathway_Homo sapiens_hsa034600.58961099
108Gap junction_Homo sapiens_hsa045400.57635829
109MAPK signaling pathway_Homo sapiens_hsa040100.56767511
110Tryptophan metabolism_Homo sapiens_hsa003800.55617008
111Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.54598047
112Parkinsons disease_Homo sapiens_hsa050120.53842125
113Focal adhesion_Homo sapiens_hsa045100.53455940
114PPAR signaling pathway_Homo sapiens_hsa033200.52123488
115Oxidative phosphorylation_Homo sapiens_hsa001900.51833736
116Huntingtons disease_Homo sapiens_hsa050160.50717123
117Regulation of actin cytoskeleton_Homo sapiens_hsa048100.50458518
118Alcoholism_Homo sapiens_hsa050340.50149170
119Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.49871036
120Fatty acid metabolism_Homo sapiens_hsa012120.49563267
121cGMP-PKG signaling pathway_Homo sapiens_hsa040220.47925599
122Inositol phosphate metabolism_Homo sapiens_hsa005620.46928722
123Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.45131127
124Rap1 signaling pathway_Homo sapiens_hsa040150.44879254
125Vitamin B6 metabolism_Homo sapiens_hsa007500.44689417
126ABC transporters_Homo sapiens_hsa020100.42339635
127Retinol metabolism_Homo sapiens_hsa008300.42223668
128Long-term potentiation_Homo sapiens_hsa047200.42182491
129Maturity onset diabetes of the young_Homo sapiens_hsa049500.40996223
130Sphingolipid signaling pathway_Homo sapiens_hsa040710.40530619
131Phagosome_Homo sapiens_hsa041450.40132660

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