NCKAP5L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1melanin biosynthetic process (GO:0042438)6.83247900
2melanin metabolic process (GO:0006582)6.15242773
3secondary metabolite biosynthetic process (GO:0044550)5.29553904
4semaphorin-plexin signaling pathway (GO:0071526)3.48386162
5atrioventricular valve morphogenesis (GO:0003181)3.47265430
6mannose metabolic process (GO:0006013)3.44111324
7establishment of nucleus localization (GO:0040023)3.31532304
8cell migration involved in heart development (GO:0060973)3.21179580
9positive regulation of receptor recycling (GO:0001921)3.19464967
10axon extension involved in axon guidance (GO:0048846)3.14052485
11neuron projection extension involved in neuron projection guidance (GO:1902284)3.14052485
12regulation of NFAT protein import into nucleus (GO:0051532)3.09321686
13layer formation in cerebral cortex (GO:0021819)3.02096806
14cytoskeletal anchoring at plasma membrane (GO:0007016)3.00264052
15venous blood vessel morphogenesis (GO:0048845)2.97054830
16regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.96251308
17planar cell polarity pathway involved in neural tube closure (GO:0090179)2.94665487
18protein heterotrimerization (GO:0070208)2.92007961
19adherens junction assembly (GO:0034333)2.90357124
20negative regulation of cell size (GO:0045792)2.88826608
21peptidyl-lysine dimethylation (GO:0018027)2.85080680
22pre-miRNA processing (GO:0031054)2.84413003
23cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.83887429
24vascular endothelial growth factor signaling pathway (GO:0038084)2.77813722
25stress fiber assembly (GO:0043149)2.76474670
26protein localization to endosome (GO:0036010)2.75047343
27somatic stem cell division (GO:0048103)2.71617270
28negative regulation of cell killing (GO:0031342)2.69484701
29negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.69484701
30negative regulation of catenin import into nucleus (GO:0035414)2.69367083
31vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.67763619
32positive regulation of myotube differentiation (GO:0010831)2.66174191
33positive regulation of histone deacetylation (GO:0031065)2.62549856
34substrate-dependent cell migration (GO:0006929)2.61683485
35insulin-like growth factor receptor signaling pathway (GO:0048009)2.61100892
36hippo signaling (GO:0035329)2.59709062
37sodium ion export (GO:0071436)2.57470320
38cell junction maintenance (GO:0034331)2.56414786
39plasma membrane repair (GO:0001778)2.56349289
40endothelial cell chemotaxis (GO:0035767)2.51441691
41dosage compensation (GO:0007549)2.51433685
42outer ear morphogenesis (GO:0042473)2.47441925
43chondroitin sulfate biosynthetic process (GO:0030206)2.47187458
44embryonic foregut morphogenesis (GO:0048617)2.45344075
45dermatan sulfate metabolic process (GO:0030205)2.45155108
46negative regulation of fatty acid transport (GO:2000192)2.44059810
47cell migration in hindbrain (GO:0021535)2.43484405
48regulation of ARF GTPase activity (GO:0032312)2.42984361
49apoptotic cell clearance (GO:0043277)2.42445798
50cortical actin cytoskeleton organization (GO:0030866)2.41544277
51regulation of extracellular matrix disassembly (GO:0010715)2.41492958
52basement membrane organization (GO:0071711)2.41173498
53heparan sulfate proteoglycan metabolic process (GO:0030201)2.40914769
54negative regulation of erythrocyte differentiation (GO:0045647)2.39835771
55establishment of apical/basal cell polarity (GO:0035089)2.38686630
56glucocorticoid receptor signaling pathway (GO:0042921)2.37561136
57NLS-bearing protein import into nucleus (GO:0006607)2.36562975
58apoptotic process involved in morphogenesis (GO:0060561)2.36182596
59outflow tract septum morphogenesis (GO:0003148)2.35957368
60histone H3-K9 demethylation (GO:0033169)2.35785923
61response to laminar fluid shear stress (GO:0034616)2.35273204
62response to fluid shear stress (GO:0034405)2.35252043
63cytoplasmic mRNA processing body assembly (GO:0033962)2.35240127
64anatomical structure regression (GO:0060033)2.35088601
65cell-substrate adherens junction assembly (GO:0007045)2.34725564
66focal adhesion assembly (GO:0048041)2.34725564
67tooth mineralization (GO:0034505)2.34032600
68collagen metabolic process (GO:0032963)2.33535981
69endodermal cell differentiation (GO:0035987)2.31689967
70developmental pigmentation (GO:0048066)2.30452319
71regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.30184625
72cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.30114066
73skin morphogenesis (GO:0043589)2.29947132
74negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.29156702
75chondrocyte proliferation (GO:0035988)2.28800817
76phagocytosis, recognition (GO:0006910)2.28377128
77heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.28146157
78retina vasculature morphogenesis in camera-type eye (GO:0061299)2.28137652
79germ cell migration (GO:0008354)2.28025259
80positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.27483883
81negative regulation of granulocyte differentiation (GO:0030853)2.26389314
82cell-substrate junction assembly (GO:0007044)2.25329094
83negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.25277413
84glial cell migration (GO:0008347)2.24465424
85collagen catabolic process (GO:0030574)2.24346398
86atrial septum morphogenesis (GO:0060413)2.24089497
87polarized epithelial cell differentiation (GO:0030859)2.23249798
88positive regulation of odontogenesis (GO:0042482)2.23058356
89establishment or maintenance of monopolar cell polarity (GO:0061339)2.22813946
90establishment of monopolar cell polarity (GO:0061162)2.22813946
91regulation of early endosome to late endosome transport (GO:2000641)2.22422820
92intracellular estrogen receptor signaling pathway (GO:0030520)2.22377360
93heart morphogenesis (GO:0003007)2.22256669
94lymph vessel development (GO:0001945)2.21972329
95bone trabecula formation (GO:0060346)2.21814722
96chondroitin sulfate catabolic process (GO:0030207)2.21781424
97cardiac myofibril assembly (GO:0055003)2.21598536
98negative regulation of smooth muscle cell migration (GO:0014912)2.20794770
99gastrulation with mouth forming second (GO:0001702)2.20615943
100paraxial mesoderm development (GO:0048339)2.20168474
101positive regulation of dendrite morphogenesis (GO:0050775)2.18714502
102protein targeting to plasma membrane (GO:0072661)2.18352477
103positive regulation of epithelial to mesenchymal transition (GO:0010718)2.17700805
104heterochromatin organization (GO:0070828)2.17689651
105endothelial cell morphogenesis (GO:0001886)2.16874840
106Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.16859839
107regulation of SMAD protein import into nucleus (GO:0060390)2.16642259
108cell migration involved in sprouting angiogenesis (GO:0002042)2.16588739
109extracellular matrix assembly (GO:0085029)2.16576502
110regulation of axon extension involved in axon guidance (GO:0048841)2.14771317
111adherens junction organization (GO:0034332)2.14490970
112positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.14397484
113extracellular matrix disassembly (GO:0022617)2.13795589
114cell-cell junction maintenance (GO:0045217)2.13794587
115positive regulation of RNA splicing (GO:0033120)2.13460085
116convergent extension (GO:0060026)2.13424169
117dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.13325143
118positive regulation of axon extension (GO:0045773)2.12252487
119myotube differentiation (GO:0014902)2.12177972
120endothelial tube morphogenesis (GO:0061154)2.12014501
121morphogenesis of an endothelium (GO:0003159)2.12014501
122heart valve morphogenesis (GO:0003179)2.11806611
123barbed-end actin filament capping (GO:0051016)2.11708661
124neural tube development (GO:0021915)2.11571003
125cardiac muscle cell proliferation (GO:0060038)2.11284091
126fibroblast migration (GO:0010761)2.11170462
127positive thymic T cell selection (GO:0045059)2.10961595
128regulation of translational fidelity (GO:0006450)2.10920642
129cerebellar Purkinje cell layer development (GO:0021680)2.10521779
130wound healing, spreading of epidermal cells (GO:0035313)2.10084121
131glomerular filtration (GO:0003094)2.09677698
132regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.09638277
133epithelial cell-cell adhesion (GO:0090136)2.09513153
134stress granule assembly (GO:0034063)2.09475837
135positive regulation of protein dephosphorylation (GO:0035307)2.08874629
136cellular response to monoamine stimulus (GO:0071868)2.08699870
137cellular response to catecholamine stimulus (GO:0071870)2.08699870
138Golgi transport vesicle coating (GO:0048200)2.08504613
139COPI coating of Golgi vesicle (GO:0048205)2.08504613
140protein-DNA complex disassembly (GO:0032986)2.08346186
141nucleosome disassembly (GO:0006337)2.08346186
142multicellular organismal macromolecule metabolic process (GO:0044259)2.08297430
143mitotic G1 DNA damage checkpoint (GO:0031571)2.08087898
144regulation of establishment of planar polarity (GO:0090175)2.07534542
145dermatan sulfate biosynthetic process (GO:0030208)2.07030643
146glomerular basement membrane development (GO:0032836)2.06998527
147negative regulation of chondrocyte differentiation (GO:0032331)2.06937568
148maternal placenta development (GO:0001893)2.06832755
149endocardial cushion morphogenesis (GO:0003203)2.06681720
150G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.06648064
151glial cell proliferation (GO:0014009)2.06513957
152apoptotic process involved in development (GO:1902742)2.06479243
153receptor catabolic process (GO:0032801)2.06365285
154mRNA stabilization (GO:0048255)2.05825049
155RNA stabilization (GO:0043489)2.05825049
156epithelial cell differentiation involved in prostate gland development (GO:0060742)2.05054849
157collagen fibril organization (GO:0030199)2.04907588
158positive regulation of SMAD protein import into nucleus (GO:0060391)2.03974554
159syncytium formation by plasma membrane fusion (GO:0000768)2.03963959
160neural tube closure (GO:0001843)2.03661934
161positive regulation of blood vessel endothelial cell migration (GO:0043536)2.03604104

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EGR1_19374776_ChIP-ChIP_THP-1_Human3.95466899
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.91565605
3MYC_22102868_ChIP-Seq_BL_Human3.21581369
4KDM2B_26808549_Chip-Seq_SUP-B15_Human3.04823738
5KDM2B_26808549_Chip-Seq_DND41_Human2.91794266
6EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.86218968
7ZFP281_18757296_ChIP-ChIP_E14_Mouse2.79268011
8STAT6_21828071_ChIP-Seq_BEAS2B_Human2.66576971
9TCF7_22412390_ChIP-Seq_EML_Mouse2.58917450
10EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.46340359
11WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.46154629
12KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.44052120
13ELK3_25401928_ChIP-Seq_HUVEC_Human2.43520397
14ZFP281_27345836_Chip-Seq_ESCs_Mouse2.42646001
15VDR_21846776_ChIP-Seq_THP-1_Human2.36402029
16ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.36048843
17KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.30417217
18KDM2B_26808549_Chip-Seq_K562_Human2.23742919
19KDM2B_26808549_Chip-Seq_JURKAT_Human2.19762021
20* DMRT1_23473982_ChIP-Seq_TESTES_Mouse2.16818496
21LXR_22292898_ChIP-Seq_THP-1_Human2.07637744
22TP63_17297297_ChIP-ChIP_HaCaT_Human2.00701643
23TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.87379760
24SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.83004013
25* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.81717861
26P300_27058665_Chip-Seq_ZR-75-30cells_Human1.79446000
27FOXM1_23109430_ChIP-Seq_U2OS_Human1.76584395
28STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.74880368
29MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.70887766
30TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.68077836
31EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.65660613
32STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.65192111
33RARG_19884340_ChIP-ChIP_MEFs_Mouse1.61267780
34HIF1A_21447827_ChIP-Seq_MCF-7_Human1.60299070
35UTX_26944678_Chip-Seq_JUKART_Human1.54063028
36PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.53842163
37RACK7_27058665_Chip-Seq_MCF-7_Human1.50722188
38THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.50473244
39CLOCK_20551151_ChIP-Seq_293T_Human1.50173033
40KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.48589396
41* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.47022318
42TRIM28_21343339_ChIP-Seq_HEK293_Human1.45727339
43* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.45271800
44* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.43670616
45VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.43110927
46SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.42830479
47ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.42424657
48CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.42328250
49MAF_26560356_Chip-Seq_TH1_Human1.40489280
50SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.36382684
51* TET1_21451524_ChIP-Seq_MESCs_Mouse1.35984810
52NFIB_24661679_ChIP-Seq_LUNG_Mouse1.34815444
53DROSHA_22980978_ChIP-Seq_HELA_Human1.34075462
54VDR_24763502_ChIP-Seq_THP-1_Human1.33905296
55ESR1_21235772_ChIP-Seq_MCF-7_Human1.32921041
56* CTCF_27219007_Chip-Seq_Bcells_Human1.28042280
57DNAJC2_21179169_ChIP-ChIP_NT2_Human1.27155409
58SPI1_23127762_ChIP-Seq_K562_Human1.26316384
59CREB1_26743006_Chip-Seq_LNCaP_Human1.26095534
60ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.24890418
61TP53_22127205_ChIP-Seq_IMR90_Human1.24028725
62ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.21470653
63SMC1_22415368_ChIP-Seq_MEFs_Mouse1.20563333
64IKZF1_21737484_ChIP-ChIP_HCT116_Human1.20088292
65TET1_21490601_ChIP-Seq_MESCs_Mouse1.20079316
66ISL1_27105846_Chip-Seq_CPCs_Mouse1.19814799
67GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.19016103
68KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.18926350
69FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.18533200
70FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.18246731
71TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.18087414
72ATF3_27146783_Chip-Seq_COLON_Human1.17955921
73SMC3_22415368_ChIP-Seq_MEFs_Mouse1.16794210
74TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.14103028
75CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.13681994
76PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.13218519
77SOX9_24532713_ChIP-Seq_HFSC_Mouse1.13208413
78OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.13087691
79RARB_27405468_Chip-Seq_BRAIN_Mouse1.12983666
80CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.12367628
81GATA1_19941827_ChIP-Seq_MEL_Mouse1.12093562
82ELF1_20517297_ChIP-Seq_JURKAT_Human1.12061859
83ESR2_21235772_ChIP-Seq_MCF-7_Human1.11815671
84E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.10840872
85SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.10495777
86WT1_25993318_ChIP-Seq_PODOCYTE_Human1.08449213
87TP63_22573176_ChIP-Seq_HFKS_Human1.08231119
88JARID2_20075857_ChIP-Seq_MESCs_Mouse1.07908780
89MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.07206669
90FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.07157010
91NCOR1_26117541_ChIP-Seq_K562_Human1.06897901
92* TP53_23651856_ChIP-Seq_MEFs_Mouse1.06696231
93SUZ12_27294783_Chip-Seq_ESCs_Mouse1.06354543
94RING1B_27294783_Chip-Seq_NPCs_Mouse1.06302257
95RUNX1_27514584_Chip-Seq_MCF-7_Human1.05693454
96TP53_20018659_ChIP-ChIP_R1E_Mouse1.05690256
97CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.03397625
98EZH2_18974828_ChIP-Seq_MESCs_Mouse1.03204473
99RNF2_18974828_ChIP-Seq_MESCs_Mouse1.03204473
100GATA2_21666600_ChIP-Seq_HMVEC_Human1.03086339
101ZNF263_19887448_ChIP-Seq_K562_Human1.02692296
102RNF2_27304074_Chip-Seq_ESCs_Mouse1.02260574
103CTCF_27219007_Chip-Seq_ERYTHROID_Human1.02014941
104PKCTHETA_26484144_Chip-Seq_BREAST_Human1.00950609
105SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.00574107
106UBF1/2_26484160_Chip-Seq_HMECs_Human1.00560467
107EED_16625203_ChIP-ChIP_MESCs_Mouse1.00473525
108BCOR_27268052_Chip-Seq_Bcells_Human0.99974519
109RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.98969059
110TBX20_22080862_ChIP-Seq_HEART_Mouse0.98621790
111TBX20_22328084_ChIP-Seq_HEART_Mouse0.98621790
112CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.97575828
113EZH2_27294783_Chip-Seq_ESCs_Mouse0.97188124
114SA1_27219007_Chip-Seq_ERYTHROID_Human0.97176802
115SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.95816873
116MTF2_20144788_ChIP-Seq_MESCs_Mouse0.94892434
117SMC4_20622854_ChIP-Seq_HELA_Human0.94807875
118RUNX1_22412390_ChIP-Seq_EML_Mouse0.94279194
119ERG_21242973_ChIP-ChIP_JURKAT_Human0.93843278
120ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.92920905
121P68_20966046_ChIP-Seq_HELA_Human0.92372682
122NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.92352663
123DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.91619932
124NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.91460310
125* RING1B_27294783_Chip-Seq_ESCs_Mouse0.91095296
126MAF_26560356_Chip-Seq_TH2_Human0.89556484
127ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.89483139
128* BRD4_27068464_Chip-Seq_AML-cells_Mouse0.89194821
129* MITF_21258399_ChIP-Seq_MELANOMA_Human0.87536600

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000372_irregular_coat_pigmentation4.35625253
2MP0005171_absent_coat_pigmentation3.40612730
3MP0003705_abnormal_hypodermis_morpholog3.38527027
4MP0005257_abnormal_intraocular_pressure2.96522338
5MP0005058_abnormal_lysosome_morphology2.95797461
6MP0008438_abnormal_cutaneous_collagen2.71433930
7MP0000569_abnormal_digit_pigmentation2.46409935
8MP0005623_abnormal_meninges_morphology2.43862210
9MP0000371_diluted_coat_color2.40895056
10MP0000733_abnormal_muscle_development2.24474144
11MP0005409_darkened_coat_color2.03235842
12MP0005076_abnormal_cell_differentiation2.00740453
13MP0010368_abnormal_lymphatic_system1.92150422
14MP0008961_abnormal_basal_metabolism1.87900475
15MP0010030_abnormal_orbit_morphology1.86778897
16MP0003279_aneurysm1.86215880
17MP0003122_maternal_imprinting1.83727592
18MP0009278_abnormal_bone_marrow1.81964732
19MP0009840_abnormal_foam_cell1.75540126
20MP0001849_ear_inflammation1.73204623
21MP0001348_abnormal_lacrimal_gland1.67317274
22MP0003878_abnormal_ear_physiology1.66597285
23MP0005377_hearing/vestibular/ear_phenot1.66597285
24MP0003172_abnormal_lysosome_physiology1.66023173
25MP0002653_abnormal_ependyma_morphology1.65282388
26MP0000003_abnormal_adipose_tissue1.63251666
27MP0003283_abnormal_digestive_organ1.60191995
28MP0002108_abnormal_muscle_morphology1.55998251
29MP0003385_abnormal_body_wall1.53005218
30MP0003091_abnormal_cell_migration1.52291126
31MP0003828_pulmonary_edema1.51882137
32MP0002254_reproductive_system_inflammat1.50894488
33MP0003566_abnormal_cell_adhesion1.50324906
34MP0004858_abnormal_nervous_system1.49478174
35MP0004272_abnormal_basement_membrane1.47589662
36MP0010352_gastrointestinal_tract_polyps1.45298692
37MP0002075_abnormal_coat/hair_pigmentati1.45227598
38MP0000537_abnormal_urethra_morphology1.44960859
39MP0003329_amyloid_beta_deposits1.44628950
40MP0000013_abnormal_adipose_tissue1.41757787
41MP0002089_abnormal_postnatal_growth/wei1.41705606
42MP0008260_abnormal_autophagy1.39466566
43MP0000534_abnormal_ureter_morphology1.39255098
44MP0000759_abnormal_skeletal_muscle1.34943309
45MP0003300_gastrointestinal_ulcer1.33103808
46MP0003303_peritoneal_inflammation1.32943236
47MP0006054_spinal_hemorrhage1.32159008
48MP0004808_abnormal_hematopoietic_stem1.31384190
49MP0002877_abnormal_melanocyte_morpholog1.30882195
50MP0002896_abnormal_bone_mineralization1.30664075
51MP0003115_abnormal_respiratory_system1.29352555
52MP0005248_abnormal_Harderian_gland1.28311104
53MP0004233_abnormal_muscle_weight1.28054486
54MP0004084_abnormal_cardiac_muscle1.27658158
55MP0009053_abnormal_anal_canal1.26230526
56MP0002933_joint_inflammation1.22242358
57MP0005023_abnormal_wound_healing1.21653796
58MP0001958_emphysema1.19380552
59MP0005595_abnormal_vascular_smooth1.18748783
60MP0005503_abnormal_tendon_morphology1.17970692
61MP0002060_abnormal_skin_morphology1.17403874
62MP0004197_abnormal_fetal_growth/weight/1.16283397
63MP0003942_abnormal_urinary_system1.15827613
64MP0005375_adipose_tissue_phenotype1.15578925
65MP0000428_abnormal_craniofacial_morphol1.14946358
66MP0005390_skeleton_phenotype1.14219283
67MP0003436_decreased_susceptibility_to1.13938284
68MP0002998_abnormal_bone_remodeling1.13445058
69MP0004859_abnormal_synaptic_plasticity1.12968671
70MP0002925_abnormal_cardiovascular_devel1.10330488
71MP0005408_hypopigmentation1.07913160
72MP0001915_intracranial_hemorrhage1.07191760
73MP0005508_abnormal_skeleton_morphology1.06953219
74MP0000751_myopathy1.06861914
75MP0004130_abnormal_muscle_cell1.06836968
76MP0003121_genomic_imprinting1.06364425
77MP0001542_abnormal_bone_strength1.04871289
78MP0000767_abnormal_smooth_muscle1.04280608
79MP0001299_abnormal_eye_distance/1.03977999
80MP0002932_abnormal_joint_morphology1.03020087
81MP0002084_abnormal_developmental_patter1.02389154
82MP0004510_myositis1.02381336
83MP0005174_abnormal_tail_pigmentation1.01387426
84MP0002938_white_spotting1.00860144
85MP0005275_abnormal_skin_tensile1.00523328
86MP0004036_abnormal_muscle_relaxation1.00233481
87MP0000749_muscle_degeneration0.99184488
88MP0005197_abnormal_uvea_morphology0.98890697
89MP0005451_abnormal_body_composition0.98530438
90MP0000747_muscle_weakness0.98053691
91MP0002295_abnormal_pulmonary_circulatio0.97324918
92MP0001324_abnormal_eye_pigmentation0.96451046
93MP0003935_abnormal_craniofacial_develop0.96242212
94MP0003191_abnormal_cellular_cholesterol0.96175717
95MP0000678_abnormal_parathyroid_gland0.95337793
96MP0002095_abnormal_skin_pigmentation0.94519232
97MP0003634_abnormal_glial_cell0.94454541
98MP0000015_abnormal_ear_pigmentation0.92948190
99MP0002092_abnormal_eye_morphology0.92588946
100MP0003567_abnormal_fetal_cardiomyocyte0.91871908
101MP0002396_abnormal_hematopoietic_system0.89117365
102MP0010630_abnormal_cardiac_muscle0.88821874
103MP0002697_abnormal_eye_size0.87289786
104MP0002085_abnormal_embryonic_tissue0.87250439
105MP0001533_abnormal_skeleton_physiology0.87151810
106MP0006138_congestive_heart_failure0.86454377
107MP0001186_pigmentation_phenotype0.85696481
108MP0003123_paternal_imprinting0.84473332
109MP0004087_abnormal_muscle_fiber0.84179320
110MP0010307_abnormal_tumor_latency0.83438237
111MP0003045_fibrosis0.83222954
112MP0003119_abnormal_digestive_system0.82577906
113MP0005369_muscle_phenotype0.81864400
114MP0002116_abnormal_craniofacial_bone0.81756775
115MP0005167_abnormal_blood-brain_barrier0.80686370
116MP0000350_abnormal_cell_proliferation0.79732403
117MP0003984_embryonic_growth_retardation0.79246018
118MP0002088_abnormal_embryonic_growth/wei0.79113460
119MP0000266_abnormal_heart_morphology0.78882191
120MP0002113_abnormal_skeleton_development0.78822978
121MP0002106_abnormal_muscle_physiology0.77425740
122MP0002269_muscular_atrophy0.77296416
123MP0002090_abnormal_vision0.77040695
124MP0005330_cardiomyopathy0.76817341
125MP0003861_abnormal_nervous_system0.76681523
126MP0000750_abnormal_muscle_regeneration0.75911814
127MP0005397_hematopoietic_system_phenotyp0.75222839
128MP0001545_abnormal_hematopoietic_system0.75222839
129MP0005670_abnormal_white_adipose0.75127739
130MP0002282_abnormal_trachea_morphology0.75022201
131MP0002249_abnormal_larynx_morphology0.74237479
132MP0002086_abnormal_extraembryonic_tissu0.74081500
133MP0008007_abnormal_cellular_replicative0.73804723
134MP0001175_abnormal_lung_morphology0.73264195
135MP0000163_abnormal_cartilage_morphology0.73066922
136MP0009384_cardiac_valve_regurgitation0.72239202
137MP0001614_abnormal_blood_vessel0.72092951
138MP0008770_decreased_survivor_rate0.71179177
139MP0005380_embryogenesis_phenotype0.70924789
140MP0001672_abnormal_embryogenesis/_devel0.70924789
141MP0000604_amyloidosis0.69894289
142MP0002127_abnormal_cardiovascular_syste0.69758477
143MP0002128_abnormal_blood_circulation0.69287901
144MP0001697_abnormal_embryo_size0.69059389
145MP0001730_embryonic_growth_arrest0.68868507
146MP0002114_abnormal_axial_skeleton0.67705404
147MP0005666_abnormal_adipose_tissue0.67325634
148MP0003453_abnormal_keratinocyte_physiol0.67214643
149MP0009250_abnormal_appendicular_skeleto0.66551068
150MP0000049_abnormal_middle_ear0.65676973
151MP0001243_abnormal_dermal_layer0.64853556

Predicted human phenotypes

RankGene SetZ-score
1Cerebral aneurysm (HP:0004944)4.12593287
2Hyperacusis (HP:0010780)3.71830543
3Protrusio acetabuli (HP:0003179)3.55977818
4Shallow orbits (HP:0000586)3.55372070
5Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.23277791
6Short 4th metacarpal (HP:0010044)3.23277791
7Bladder diverticulum (HP:0000015)3.21233509
8Cervical subluxation (HP:0003308)3.12864801
9Premature rupture of membranes (HP:0001788)3.04735747
10Renal duplication (HP:0000075)3.00017140
11Aortic aneurysm (HP:0004942)2.97975175
12Ulnar bowing (HP:0003031)2.83798237
13Spinal rigidity (HP:0003306)2.79888819
14Broad face (HP:0000283)2.75050719
15Obstructive sleep apnea (HP:0002870)2.73871095
16Round ear (HP:0100830)2.69927426
17Upper limb amyotrophy (HP:0009129)2.66841476
18Distal upper limb amyotrophy (HP:0007149)2.66841476
19Ankle contracture (HP:0006466)2.63400014
20Bowel diverticulosis (HP:0005222)2.60484455
21Elfin facies (HP:0004428)2.58073419
22Subacute progressive viral hepatitis (HP:0006572)2.54527459
23Vertebral compression fractures (HP:0002953)2.53193865
24Aortic dissection (HP:0002647)2.52075078
25Mitral valve prolapse (HP:0001634)2.51037883
26Hand muscle atrophy (HP:0009130)2.50944011
27Abnormality of the 4th metacarpal (HP:0010012)2.48124484
28Renovascular hypertension (HP:0100817)2.47178214
29Abnormality of dentin (HP:0010299)2.42129199
30Arterial tortuosity (HP:0005116)2.42104829
31Vascular tortuosity (HP:0004948)2.40532758
32Hypopigmentation of the fundus (HP:0007894)2.39918389
33Flat cornea (HP:0007720)2.38862058
34Joint stiffness (HP:0001387)2.38707660
35Dilatation of the ascending aorta (HP:0005111)2.38312100
36Stridor (HP:0010307)2.37516761
37Pointed chin (HP:0000307)2.36469454
38Ocular albinism (HP:0001107)2.35048872
39Abnormality of polysaccharide metabolism (HP:0011012)2.32898150
40Abnormality of glycosaminoglycan metabolism (HP:0004371)2.32898150
41Abnormality of mucopolysaccharide metabolism (HP:0011020)2.32898150
42Insomnia (HP:0100785)2.32254254
43Genu recurvatum (HP:0002816)2.29308361
44Overriding aorta (HP:0002623)2.29211378
45Dysostosis multiplex (HP:0000943)2.28758161
46Biconcave vertebral bodies (HP:0004586)2.28040988
47Urinary glycosaminoglycan excretion (HP:0003541)2.27797035
48Mucopolysacchariduria (HP:0008155)2.27797035
49Distal lower limb amyotrophy (HP:0008944)2.23435664
50Broad metatarsal (HP:0001783)2.20605234
51Spondylolisthesis (HP:0003302)2.19071457
52Aneurysm (HP:0002617)2.17215799
53Abnormality of skeletal muscle fiber size (HP:0012084)2.17111500
54Distal lower limb muscle weakness (HP:0009053)2.15623979
55Urethral obstruction (HP:0000796)2.14920499
56Turricephaly (HP:0000262)2.12966390
57Deviation of the hallux (HP:0010051)2.12811251
58Iris hypopigmentation (HP:0007730)2.11390276
59Hallux valgus (HP:0001822)2.11318600
60Disproportionate tall stature (HP:0001519)2.10108808
61Neoplasm of the heart (HP:0100544)2.08570809
62Peritonitis (HP:0002586)2.06981500
63Macroorchidism (HP:0000053)2.06660006
64Difficulty climbing stairs (HP:0003551)2.05264636
65Ulnar deviation of the wrist (HP:0003049)2.03749548
66Striae distensae (HP:0001065)2.01749488
67Enlarged penis (HP:0000040)2.01629484
68Aplasia/Hypoplasia of the macula (HP:0008059)2.01617443
69Scapular winging (HP:0003691)2.00140259
70Aortic regurgitation (HP:0001659)1.99982228
71J-shaped sella turcica (HP:0002680)1.98917482
72Narrow palate (HP:0000189)1.97571917
73Lymphangioma (HP:0100764)1.97278963
74Blue irides (HP:0000635)1.96867600
75Aplasia/Hypoplasia affecting the retina (HP:0008061)1.93940511
76Arnold-Chiari malformation (HP:0002308)1.93449288
77Atrophic scars (HP:0001075)1.90112588
78Blue sclerae (HP:0000592)1.89833826
79Wrist flexion contracture (HP:0001239)1.89506227
80Abnormality of glycolipid metabolism (HP:0010969)1.89143772
81Abnormality of liposaccharide metabolism (HP:0010968)1.89143772
82Abnormality of glycosphingolipid metabolism (HP:0004343)1.89143772
83Increased density of long bones (HP:0006392)1.88218211
84Persistence of primary teeth (HP:0006335)1.86289930
85Hyperextensible skin (HP:0000974)1.85371274
86Easy fatigability (HP:0003388)1.81375698
87Absent frontal sinuses (HP:0002688)1.81071706
88Trigonocephaly (HP:0000243)1.81071257
89Centrally nucleated skeletal muscle fibers (HP:0003687)1.79692244
90Ectopia lentis (HP:0001083)1.79575717
91Aortic valve stenosis (HP:0001650)1.78775610
92Neonatal short-limb short stature (HP:0008921)1.78154830
93Thin ribs (HP:0000883)1.77908808
94Increased cerebral lipofuscin (HP:0011813)1.77897335
95Bicuspid aortic valve (HP:0001647)1.77702212
96Asymmetry of the thorax (HP:0001555)1.77034260
97Increased nuchal translucency (HP:0010880)1.76788039
98Asymmetric septal hypertrophy (HP:0001670)1.76655858
99Wide anterior fontanel (HP:0000260)1.76345026
100Supernumerary ribs (HP:0005815)1.75047182
101Generalized amyotrophy (HP:0003700)1.74090241
102Abnormality of the lower motor neuron (HP:0002366)1.73946575
103Broad thumb (HP:0011304)1.73880116
104Soft skin (HP:0000977)1.73777496
105Joint laxity (HP:0001388)1.70367466
106Thin bony cortex (HP:0002753)1.69763026
107Inguinal hernia (HP:0000023)1.68952674
108Deformed sella turcica (HP:0002681)1.67483119
109Elbow flexion contracture (HP:0002987)1.67139904
110Slender build (HP:0001533)1.67119407
111Long toe (HP:0010511)1.66799877
112Infantile muscular hypotonia (HP:0008947)1.66140960
113Mitral regurgitation (HP:0001653)1.65759816
114Hypoplasia of the iris (HP:0007676)1.64907452
115Narrow nasal bridge (HP:0000446)1.64544323
116Astrocytoma (HP:0009592)1.64089874
117Abnormality of the astrocytes (HP:0100707)1.64089874
118Wormian bones (HP:0002645)1.63982939
119Natal tooth (HP:0000695)1.63902736
120Short nail (HP:0001799)1.63716755
121Flexion contracture of toe (HP:0005830)1.63160478
122Joint contractures involving the joints of the feet (HP:0100492)1.63160478
123Annular pancreas (HP:0001734)1.63089792
124Pulmonary artery stenosis (HP:0004415)1.63071138
125Aplasia of the musculature (HP:0100854)1.62486369
126Abnormality of the radial head (HP:0003995)1.62009504
127Exostoses (HP:0100777)1.61634254
128Type 1 muscle fiber predominance (HP:0003803)1.60928689
129Camptodactyly of toe (HP:0001836)1.59836495
130Sacral dimple (HP:0000960)1.59479044
131Mildly elevated creatine phosphokinase (HP:0008180)1.59350993
132Spinal muscular atrophy (HP:0007269)1.57060916
133Long eyelashes (HP:0000527)1.56147894
134Dislocated radial head (HP:0003083)1.56040317
135Generalized hypotonia (HP:0001290)1.53928168
136Hypoventilation (HP:0002791)1.53835018
137Increased connective tissue (HP:0009025)1.53236599
138Fragile skin (HP:0001030)1.52695863
139Megalocornea (HP:0000485)1.52399975
140Broad ribs (HP:0000885)1.51939240
141Broad phalanges of the hand (HP:0009768)1.51633816
142Lower limb amyotrophy (HP:0007210)1.51047300
143Fibroma (HP:0010614)1.50953266
144Increased variability in muscle fiber diameter (HP:0003557)1.50712545
145Long palpebral fissure (HP:0000637)1.50167606
146Broad palm (HP:0001169)1.50050878
147Supranuclear gaze palsy (HP:0000605)1.49379173
148Skin tags (HP:0010609)1.48975144
149Hematochezia (HP:0002573)1.47136617

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.65257009
2PKN24.53796016
3MAP3K103.37785965
4EEF2K3.19247749
5RIPK13.01091394
6SMG12.33324674
7PDGFRA2.28135258
8CDK122.24115396
9BMX2.16666089
10ICK2.12330579
11TGFBR21.80925269
12PTK61.79289863
13CAMK1G1.72461571
14PRPF4B1.71740969
15SIK21.71380078
16KSR11.69200668
17MAP2K31.67574192
18TTN1.66481136
19TYRO31.66106756
20CAMK1D1.65004045
21EPHB21.62945918
22MST1R1.60375894
23DDR21.58645840
24LATS21.53828909
25PAK61.50842694
26PAK41.50775361
27MAP3K111.49007142
28PAK21.41084605
29PRKD31.37733807
30EPHA31.37311821
31MTOR1.36473792
32ERN11.35475778
33MAP4K11.24293627
34TAOK11.23132541
35MAP3K61.20725359
36DMPK1.19972802
37SIK11.19775464
38ALK1.18737988
39IRAK31.18313080
40MAP3K31.18159758
41SCYL21.12205050
42MARK31.10385003
43CAMKK11.06886914
44RET1.05267356
45MAP3K91.04332120
46TESK11.03607651
47SIK31.02770930
48PDGFRB1.02760291
49RPS6KL11.01941490
50RPS6KC11.01941490
51PTK21.01639009
52KSR20.98421422
53BRD40.96509762
54MAPK70.95424225
55PDPK10.93298039
56MOS0.90763446
57MET0.90756448
58MUSK0.86699822
59LRRK20.84851610
60MAPK120.84624480
61RPS6KA60.84113364
62MAP2K20.82511373
63FGFR10.81907214
64FGFR40.80461228
65MARK20.80419951
66LIMK10.79573439
67MAP3K70.77149144
68TNK20.75768480
69NTRK10.74379999
70LATS10.73261636
71MARK10.73013865
72CLK10.72342402
73NTRK20.71815351
74PRKCH0.70880807
75HIPK20.69564446
76ERBB20.66356479
77EPHB10.65659618
78BLK0.63651528
79MINK10.62998510
80ZAP700.62646096
81FGFR20.62502246
82NEK10.62480802
83ILK0.62388220
84HCK0.60801205
85CDK90.60469913
86PRKD20.60364015
87ROCK10.60220499
88KIT0.59966318
89MYLK0.58548406
90CDC42BPA0.58495775
91STK100.57372382
92KDR0.56223633
93MAP3K10.55682356
94TSSK60.55089050
95CAMK40.55035412
96CDK60.54388849
97TAOK20.53864671
98ITK0.53846681
99FGFR30.53610597
100PAK30.53197629
101MAPKAPK30.53059199
102EPHA20.52386309
103NEK20.52250009
104RPS6KA20.49305899
105PRKD10.49134691
106MAP3K130.48879596
107PRKAA10.48787632
108PRKG20.48425699
109UHMK10.47427670
110CSF1R0.47125521
111MAPK40.47057253
112MAP2K10.46956199
113DYRK1B0.46197164
114CHUK0.45456625
115MAPK110.45398835
116PDK10.45227472
117RPS6KB20.43461883
118SRC0.43443057
119TBK10.42701530
120TYK20.41214207
121CSNK1A1L0.40628643
122CAMK10.40428991
123RPS6KA10.40398021
124PTK2B0.40370970
125TGFBR10.40321199
126JAK30.40046641
127STK380.39771560
128PRKAA20.39366288
129PIM20.39291856
130MAPK10.38711403
131FLT30.37878217
132CDK40.37630133
133MAPK80.37018991
134TIE10.37018632
135MAPK150.35747402
136STK110.35046384
137AKT20.34578913
138MAPK90.34122543
139CDK180.33477831
140CDK70.32472450
141MAP3K80.31895187
142INSR0.31528190
143CDK150.31264536
144CDK11A0.30191999

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005112.50323154
2Chronic myeloid leukemia_Homo sapiens_hsa052201.92419317
3Notch signaling pathway_Homo sapiens_hsa043301.84179559
4Glycosaminoglycan degradation_Homo sapiens_hsa005311.77302707
5Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.74053925
6Basal cell carcinoma_Homo sapiens_hsa052171.61195130
7Colorectal cancer_Homo sapiens_hsa052101.59947097
8Glioma_Homo sapiens_hsa052141.49978688
9Focal adhesion_Homo sapiens_hsa045101.48427253
10Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.45601383
11Adherens junction_Homo sapiens_hsa045201.45535975
12Endometrial cancer_Homo sapiens_hsa052131.44298036
13Neurotrophin signaling pathway_Homo sapiens_hsa047221.43931281
14Proteoglycans in cancer_Homo sapiens_hsa052051.43607217
15Renal cell carcinoma_Homo sapiens_hsa052111.40710910
16Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.39546044
17mTOR signaling pathway_Homo sapiens_hsa041501.34919174
18Melanogenesis_Homo sapiens_hsa049161.34546185
19Axon guidance_Homo sapiens_hsa043601.32094137
20MicroRNAs in cancer_Homo sapiens_hsa052061.30740542
21AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.30176337
22Estrogen signaling pathway_Homo sapiens_hsa049151.27422043
23Hippo signaling pathway_Homo sapiens_hsa043901.27242228
24Hedgehog signaling pathway_Homo sapiens_hsa043401.27130571
25Central carbon metabolism in cancer_Homo sapiens_hsa052301.25808249
26Thyroid hormone signaling pathway_Homo sapiens_hsa049191.24421975
27Non-small cell lung cancer_Homo sapiens_hsa052231.24119388
28VEGF signaling pathway_Homo sapiens_hsa043701.23510776
29Viral myocarditis_Homo sapiens_hsa054161.21485618
30Pancreatic cancer_Homo sapiens_hsa052121.19710036
31Dilated cardiomyopathy_Homo sapiens_hsa054141.18353920
32Osteoclast differentiation_Homo sapiens_hsa043801.17921696
33Small cell lung cancer_Homo sapiens_hsa052221.17036299
34ECM-receptor interaction_Homo sapiens_hsa045121.16755444
35Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.14232371
36Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.13692263
37Prion diseases_Homo sapiens_hsa050201.12749082
38ErbB signaling pathway_Homo sapiens_hsa040121.12527952
39Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.11350269
40Acute myeloid leukemia_Homo sapiens_hsa052211.10078797
41Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.09042216
42Dorso-ventral axis formation_Homo sapiens_hsa043201.09025761
43Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.07205510
44Rap1 signaling pathway_Homo sapiens_hsa040151.06039819
45HTLV-I infection_Homo sapiens_hsa051661.03764237
46Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.01327039
47T cell receptor signaling pathway_Homo sapiens_hsa046600.99845820
48B cell receptor signaling pathway_Homo sapiens_hsa046620.99389930
49Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.97957380
50HIF-1 signaling pathway_Homo sapiens_hsa040660.97442328
51Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.96429664
52Phospholipase D signaling pathway_Homo sapiens_hsa040720.95638050
53Pathways in cancer_Homo sapiens_hsa052000.95236982
54Wnt signaling pathway_Homo sapiens_hsa043100.95088024
55Amoebiasis_Homo sapiens_hsa051460.94622818
56Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.94040056
57AMPK signaling pathway_Homo sapiens_hsa041520.93999234
58Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.92604499
59Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.92145249
60Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.91929993
61Gap junction_Homo sapiens_hsa045400.91929183
62Aldosterone synthesis and secretion_Homo sapiens_hsa049250.90537795
63Regulation of actin cytoskeleton_Homo sapiens_hsa048100.90495369
64Endocytosis_Homo sapiens_hsa041440.89756917
65Leukocyte transendothelial migration_Homo sapiens_hsa046700.89617064
66Platelet activation_Homo sapiens_hsa046110.89617062
67Inositol phosphate metabolism_Homo sapiens_hsa005620.88802443
68Toxoplasmosis_Homo sapiens_hsa051450.87077645
69Prolactin signaling pathway_Homo sapiens_hsa049170.87007030
70MAPK signaling pathway_Homo sapiens_hsa040100.85336400
71GnRH signaling pathway_Homo sapiens_hsa049120.85305673
72Bladder cancer_Homo sapiens_hsa052190.84829151
73Hepatitis B_Homo sapiens_hsa051610.84697474
74Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.84688620
75Melanoma_Homo sapiens_hsa052180.83188040
76Ovarian steroidogenesis_Homo sapiens_hsa049130.82366256
77Prostate cancer_Homo sapiens_hsa052150.82316656
78Longevity regulating pathway - mammal_Homo sapiens_hsa042110.81627142
79Lysine degradation_Homo sapiens_hsa003100.80774181
80TNF signaling pathway_Homo sapiens_hsa046680.80738212
81Malaria_Homo sapiens_hsa051440.79631965
82Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.79003441
83Oxytocin signaling pathway_Homo sapiens_hsa049210.77398106
84Adipocytokine signaling pathway_Homo sapiens_hsa049200.77014993
85Type II diabetes mellitus_Homo sapiens_hsa049300.76629371
86Insulin signaling pathway_Homo sapiens_hsa049100.75015214
87TGF-beta signaling pathway_Homo sapiens_hsa043500.74996462
88Sphingolipid signaling pathway_Homo sapiens_hsa040710.73655112
89cGMP-PKG signaling pathway_Homo sapiens_hsa040220.73542568
90Shigellosis_Homo sapiens_hsa051310.73233745
91Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.73075579
92Choline metabolism in cancer_Homo sapiens_hsa052310.71905722
93Apoptosis_Homo sapiens_hsa042100.70909635
94PI3K-Akt signaling pathway_Homo sapiens_hsa041510.70767049
95Chemokine signaling pathway_Homo sapiens_hsa040620.69919782
96Transcriptional misregulation in cancer_Homo sapiens_hsa052020.68454254
97Salmonella infection_Homo sapiens_hsa051320.68439844
98Protein digestion and absorption_Homo sapiens_hsa049740.67866560
99Toll-like receptor signaling pathway_Homo sapiens_hsa046200.67673038
100Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.67285657
101Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.67189145
102Lysosome_Homo sapiens_hsa041420.67096443
103Phosphatidylinositol signaling system_Homo sapiens_hsa040700.66755780
104Viral carcinogenesis_Homo sapiens_hsa052030.66751531
105Leishmaniasis_Homo sapiens_hsa051400.66215042
106Ras signaling pathway_Homo sapiens_hsa040140.65952021
107Carbohydrate digestion and absorption_Homo sapiens_hsa049730.65583180
108Cholinergic synapse_Homo sapiens_hsa047250.65192534
109mRNA surveillance pathway_Homo sapiens_hsa030150.64901640
110Thyroid cancer_Homo sapiens_hsa052160.62664708
111Vascular smooth muscle contraction_Homo sapiens_hsa042700.61894792
112FoxO signaling pathway_Homo sapiens_hsa040680.61590952
113Tuberculosis_Homo sapiens_hsa051520.60703735
114Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.60677591
115Insulin resistance_Homo sapiens_hsa049310.60598703
116cAMP signaling pathway_Homo sapiens_hsa040240.57577117
117Pertussis_Homo sapiens_hsa051330.55032005
118Phagosome_Homo sapiens_hsa041450.54348104

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