NCLN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pentose-phosphate shunt (GO:0006098)4.55449020
2folic acid-containing compound biosynthetic process (GO:0009396)4.22876009
3maternal placenta development (GO:0001893)4.07714236
4NADPH regeneration (GO:0006740)4.01608943
5DNA unwinding involved in DNA replication (GO:0006268)4.00363217
6regulation of mammary gland epithelial cell proliferation (GO:0033599)3.94489410
7protein localization to endosome (GO:0036010)3.88006552
8regulation of translational fidelity (GO:0006450)3.87331138
9hemidesmosome assembly (GO:0031581)3.85473330
10protein maturation by protein folding (GO:0022417)3.81439281
11antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.76277297
12antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.76277297
13viral transcription (GO:0019083)3.72341499
14L-serine metabolic process (GO:0006563)3.61880479
15glycine metabolic process (GO:0006544)3.61825562
16phagocytosis, recognition (GO:0006910)3.55355291
17translational termination (GO:0006415)3.54248400
18cell-substrate junction assembly (GO:0007044)3.53636239
19peptidyl-arginine omega-N-methylation (GO:0035247)3.51160952
20adherens junction assembly (GO:0034333)3.48400948
21cell-substrate adherens junction assembly (GO:0007045)3.43017105
22focal adhesion assembly (GO:0048041)3.43017105
23serine family amino acid biosynthetic process (GO:0009070)3.40708396
24spliceosomal tri-snRNP complex assembly (GO:0000244)3.39891305
25translational elongation (GO:0006414)3.33804872
26pinocytosis (GO:0006907)3.33548048
27regulation of early endosome to late endosome transport (GO:2000641)3.26355314
28folic acid metabolic process (GO:0046655)3.24454083
29activation of Rac GTPase activity (GO:0032863)3.22866898
30GDP-mannose metabolic process (GO:0019673)3.19734919
31retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.17245150
32negative regulation of cell size (GO:0045792)3.14738718
33basement membrane organization (GO:0071711)3.13571654
34ribosomal small subunit assembly (GO:0000028)3.11704192
35planar cell polarity pathway involved in neural tube closure (GO:0090179)3.11283606
36T cell apoptotic process (GO:0070231)3.10752036
37mitotic chromosome condensation (GO:0007076)3.09860067
38mitotic G1 DNA damage checkpoint (GO:0031571)3.09779425
39barbed-end actin filament capping (GO:0051016)3.06923447
40mitotic nuclear envelope reassembly (GO:0007084)3.06749268
41nuclear envelope reassembly (GO:0031468)3.06749268
42regulation of cholesterol homeostasis (GO:2000188)3.05632314
43apoptotic cell clearance (GO:0043277)3.04582355
44tetrahydrofolate metabolic process (GO:0046653)3.04525382
45ncRNA 3-end processing (GO:0043628)3.02636756
46apoptotic process involved in morphogenesis (GO:0060561)3.02081696
47regulation of protein heterodimerization activity (GO:0043497)3.01325154
48glucose catabolic process (GO:0006007)2.99602015
49IMP biosynthetic process (GO:0006188)2.98133470
50histone arginine methylation (GO:0034969)2.97605701
51skin morphogenesis (GO:0043589)2.97484328
524-hydroxyproline metabolic process (GO:0019471)2.97073714
53antigen processing and presentation of endogenous antigen (GO:0019883)2.95397492
54SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.94479291
55nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.94309477
56protein complex localization (GO:0031503)2.93368595
57IMP metabolic process (GO:0046040)2.92840762
58negative regulation of fibrinolysis (GO:0051918)2.92304506
59UV protection (GO:0009650)2.91830536
60negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.91662036
61low-density lipoprotein particle clearance (GO:0034383)2.91653341
62stress fiber assembly (GO:0043149)2.88915245
63negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.88598651
64translational initiation (GO:0006413)2.87402873
65protein targeting to ER (GO:0045047)2.87048089
66positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.86783119
67mitotic G1/S transition checkpoint (GO:0044819)2.86159310
68mannose metabolic process (GO:0006013)2.84569736
69positive regulation of histone deacetylation (GO:0031065)2.82846726
70cellular protein complex localization (GO:0034629)2.81332044
71cotranslational protein targeting to membrane (GO:0006613)2.80991798
72DNA strand elongation involved in DNA replication (GO:0006271)2.80829386
73sulfur amino acid catabolic process (GO:0000098)2.77740983
74pteridine-containing compound biosynthetic process (GO:0042559)2.77266427
75positive regulation of Cdc42 GTPase activity (GO:0043089)2.77141395
76positive regulation of triglyceride biosynthetic process (GO:0010867)2.76234920
77maturation of SSU-rRNA (GO:0030490)2.75905581
78proline metabolic process (GO:0006560)2.75472300
79folic acid-containing compound metabolic process (GO:0006760)2.74754002
80positive regulation of nuclease activity (GO:0032075)2.74442902
81heterochromatin organization (GO:0070828)2.73218773
82regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.73103975
83establishment of protein localization to endoplasmic reticulum (GO:0072599)2.72231760
84serine family amino acid metabolic process (GO:0009069)2.71945383
85activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.71472426
86viral life cycle (GO:0019058)2.71151118
87nucleobase biosynthetic process (GO:0046112)2.70556159
88lysine catabolic process (GO:0006554)2.69355011
89lysine metabolic process (GO:0006553)2.69355011
90lymphocyte apoptotic process (GO:0070227)2.69062231
91regulation of fatty acid beta-oxidation (GO:0031998)2.68750974
92pentose metabolic process (GO:0019321)2.68198358
93embryonic process involved in female pregnancy (GO:0060136)2.67616074
94modulation by symbiont of host cellular process (GO:0044068)2.67054112
95cellular protein complex disassembly (GO:0043624)2.66525539
96alpha-linolenic acid metabolic process (GO:0036109)2.65808920
97proline biosynthetic process (GO:0006561)2.65703042
98response to laminar fluid shear stress (GO:0034616)2.65594758
99protein localization to endoplasmic reticulum (GO:0070972)2.65363915
100glucose 6-phosphate metabolic process (GO:0051156)2.64662887
101regulation of translational termination (GO:0006449)2.64354960
102negative regulation of viral release from host cell (GO:1902187)2.63668309
103COPI coating of Golgi vesicle (GO:0048205)2.63427622
104Golgi transport vesicle coating (GO:0048200)2.63427622
105modulation by virus of host process (GO:0019054)2.62947658
1063-UTR-mediated mRNA stabilization (GO:0070935)2.62251832
107peptidyl-arginine N-methylation (GO:0035246)2.60737614
108peptidyl-arginine methylation (GO:0018216)2.60737614
109protein localization to kinetochore (GO:0034501)2.60680092
110negative regulation of erythrocyte differentiation (GO:0045647)2.59963186
111ribosomal small subunit biogenesis (GO:0042274)2.58766811
112myeloid cell homeostasis (GO:0002262)2.58681877
113nucleobase-containing small molecule interconversion (GO:0015949)2.57462066
114DNA strand elongation (GO:0022616)2.57444607
115L-alpha-amino acid transmembrane transport (GO:1902475)2.57331804
116semaphorin-plexin signaling pathway (GO:0071526)2.57330233
117regulation of glucose import in response to insulin stimulus (GO:2001273)2.56899796
118L-phenylalanine metabolic process (GO:0006558)2.56661384
119erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.56661384
120defense response to fungus (GO:0050832)2.55718643
121apoptotic process involved in development (GO:1902742)2.54042891
122protein-lipid complex assembly (GO:0065005)2.53647945
123pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.53391610
124UMP metabolic process (GO:0046049)2.53391610
125pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.53391610
126UMP biosynthetic process (GO:0006222)2.53391610
127negative regulation of RNA splicing (GO:0033119)2.52764910
128nucleotide salvage (GO:0043173)2.51418017
129positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.51129163
130maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.50789330
131amyloid precursor protein catabolic process (GO:0042987)2.50538494
132protein autoprocessing (GO:0016540)2.50185939
133nucleoside salvage (GO:0043174)2.50059380
134positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.49540694
135formation of translation preinitiation complex (GO:0001731)2.49484628
136glyoxylate metabolic process (GO:0046487)2.49168609
137protein complex disassembly (GO:0043241)2.48964009
138rRNA transcription (GO:0009303)2.48911658
139one-carbon metabolic process (GO:0006730)2.48584733
140peptidyl-glutamic acid carboxylation (GO:0017187)2.47176391
141protein carboxylation (GO:0018214)2.47176391
142pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.47169622
143adhesion of symbiont to host (GO:0044406)2.46263542
144positive regulation of blood vessel endothelial cell migration (GO:0043536)2.45998623
145regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.45595825
146regulation of nuclease activity (GO:0032069)2.45345468
147protein retention in ER lumen (GO:0006621)2.43484262
148intracellular estrogen receptor signaling pathway (GO:0030520)2.43056029
149endoplasmic reticulum unfolded protein response (GO:0030968)2.42302762
150DNA deamination (GO:0045006)2.42284038
151endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.41826321
152hyaluronan catabolic process (GO:0030214)2.40973058
153epithelial cell differentiation involved in prostate gland development (GO:0060742)2.40491377
154epithelial cell-cell adhesion (GO:0090136)2.39814010
155NIK/NF-kappaB signaling (GO:0038061)2.33909007
156regulation of extracellular matrix disassembly (GO:0010715)2.33812926
157RNA stabilization (GO:0043489)2.33597493
158mRNA stabilization (GO:0048255)2.33597493
159protein export from nucleus (GO:0006611)2.33082603
160vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.29009147
161ER-nucleus signaling pathway (GO:0006984)2.28941395
162regulation of apoptotic process involved in morphogenesis (GO:1902337)2.28518692
163desmosome organization (GO:0002934)2.28075689
164dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.26926836
165negative regulation of fatty acid transport (GO:2000192)2.26922034
166modulation by virus of host morphology or physiology (GO:0019048)2.26423606
167cytoskeletal anchoring at plasma membrane (GO:0007016)2.24926074
168peptidyl-proline hydroxylation (GO:0019511)2.24045063

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.02544007
2* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.54212911
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.86517051
4ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.82618825
5MYC_22102868_ChIP-Seq_BL_Human2.74208447
6VDR_21846776_ChIP-Seq_THP-1_Human2.57983551
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.47647434
8MYC_18555785_ChIP-Seq_MESCs_Mouse2.47079212
9FOXM1_23109430_ChIP-Seq_U2OS_Human2.27557774
10EGR1_19374776_ChIP-ChIP_THP-1_Human2.21293532
11TP63_17297297_ChIP-ChIP_HaCaT_Human2.15903033
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.14750100
13TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.09891960
14PPARA_22158963_ChIP-Seq_LIVER_Mouse2.09214721
15NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.02454963
16ELK3_25401928_ChIP-Seq_HUVEC_Human2.01995898
17LXR_22292898_ChIP-Seq_THP-1_Human1.95745704
18RXR_22158963_ChIP-Seq_LIVER_Mouse1.90255229
19RARG_19884340_ChIP-ChIP_MEFs_Mouse1.82980313
20MYC_19079543_ChIP-ChIP_MESCs_Mouse1.81427257
21NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.79152894
22* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.70302657
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.68167011
24ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.64452599
25STAT3_1855785_ChIP-Seq_MESCs_Mouse1.63546436
26KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.61311198
27TCF7_22412390_ChIP-Seq_EML_Mouse1.58744031
28XRN2_22483619_ChIP-Seq_HELA_Human1.58426370
29KDM2B_26808549_Chip-Seq_DND41_Human1.51904199
30RACK7_27058665_Chip-Seq_MCF-7_Human1.51397801
31KDM2B_26808549_Chip-Seq_SUP-B15_Human1.49414970
32UTX_26944678_Chip-Seq_JUKART_Human1.44725786
33TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.44350988
34* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.43241269
35* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.43161042
36* MAF_26560356_Chip-Seq_TH1_Human1.42098194
37ATF3_27146783_Chip-Seq_COLON_Human1.41721118
38* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.40229268
39MYB_21317192_ChIP-Seq_ERMYB_Mouse1.37894697
40* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.36214176
41DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.34919407
42TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.33319971
43KDM2B_26808549_Chip-Seq_K562_Human1.32570318
44RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.31754369
45CLOCK_20551151_ChIP-Seq_293T_Human1.31618934
46CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.31460217
47RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.30842223
48ZNF263_19887448_ChIP-Seq_K562_Human1.30002215
49FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.29996604
50KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.29873503
51SRY_22984422_ChIP-ChIP_TESTIS_Rat1.29670594
52* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.29468817
53VDR_24763502_ChIP-Seq_THP-1_Human1.29211574
54* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.28390677
55KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.27979962
56* ETS1_20019798_ChIP-Seq_JURKAT_Human1.27029446
57ZFP281_18757296_ChIP-ChIP_E14_Mouse1.25818790
58CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.25036309
59* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.22010486
60LXR_22158963_ChIP-Seq_LIVER_Mouse1.20246696
61RUNX1_22412390_ChIP-Seq_EML_Mouse1.20204192
62P68_20966046_ChIP-Seq_HELA_Human1.18425825
63KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.18339563
64CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.18272955
65E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.18215940
66MAF_26560356_Chip-Seq_TH2_Human1.17981963
67THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.17789337
68ZFX_18555785_ChIP-Seq_MESCs_Mouse1.17619655
69NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.17447669
70* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.17351569
71* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.16997637
72MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.16336805
73NELFA_20434984_ChIP-Seq_ESCs_Mouse1.15945607
74CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.14857960
75KLF4_18555785_ChIP-Seq_MESCs_Mouse1.14531573
76ERG_21242973_ChIP-ChIP_JURKAT_Human1.13610904
77SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.13274780
78ELF1_20517297_ChIP-Seq_JURKAT_Human1.12471447
79STAT6_21828071_ChIP-Seq_BEAS2B_Human1.11718466
80SMC4_20622854_ChIP-Seq_HELA_Human1.11080095
81POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.10876113
82KDM2B_26808549_Chip-Seq_JURKAT_Human1.10583823
83* NCOR1_26117541_ChIP-Seq_K562_Human1.10240967
84CIITA_25753668_ChIP-Seq_RAJI_Human1.09392504
85TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08111224
86BCL6_27268052_Chip-Seq_Bcells_Human1.07587192
87CREB1_26743006_Chip-Seq_LNCaP_Human1.07583502
88TFEB_21752829_ChIP-Seq_HELA_Human1.06480312
89SA1_27219007_Chip-Seq_ERYTHROID_Human1.06420971
90JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.06396210
91TP53_22127205_ChIP-Seq_IMR90_Human1.06250961
92E2F1_18555785_ChIP-Seq_MESCs_Mouse1.05651019
93* HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.05601802
94UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.05243326
95BCOR_27268052_Chip-Seq_Bcells_Human1.05048146
96KDM5A_27292631_Chip-Seq_BREAST_Human1.04832139
97P300_27058665_Chip-Seq_ZR-75-30cells_Human1.04436508
98ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.03996679
99TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03924036
100PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03896496
101CTCF_27219007_Chip-Seq_ERYTHROID_Human1.03647508
102NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.03166731
103TET1_21451524_ChIP-Seq_MESCs_Mouse1.03001893
104SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.02358404
105AR_21909140_ChIP-Seq_LNCAP_Human1.01649093
106HIF1A_21447827_ChIP-Seq_MCF-7_Human1.01438652
107* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.01021418
108CTCF_21964334_Chip-Seq_Bcells_Human1.00984433
109GABP_19822575_ChIP-Seq_HepG2_Human1.00440839
110CTCF_18555785_ChIP-Seq_MESCs_Mouse1.00359518
111KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.99421647
112SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.99163508
113* SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.99026913
114UBF1/2_26484160_Chip-Seq_HMECs_Human0.98986237
115PU.1_20513432_ChIP-Seq_Bcells_Mouse0.98972796
116CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.98812190
117SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.97931653
118TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.96972773
119CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.96925568
120FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.96091747
121SPI1_23547873_ChIP-Seq_NB4_Human0.94945305
122ESR1_15608294_ChIP-ChIP_MCF-7_Human0.94849061
123* E2F4_17652178_ChIP-ChIP_JURKAT_Human0.94596813
124* DCP1A_22483619_ChIP-Seq_HELA_Human0.94387999
125NANOG_18555785_ChIP-Seq_MESCs_Mouse0.94155467
126SCL_19346495_ChIP-Seq_HPC-7_Human0.93889186
127CTCF_21964334_ChIP-Seq_BJAB-B_Human0.93266934

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.97068822
2MP0009840_abnormal_foam_cell3.53348540
3MP0005451_abnormal_body_composition3.28645497
4MP0008438_abnormal_cutaneous_collagen2.92316157
5MP0002877_abnormal_melanocyte_morpholog2.86285087
6MP0005360_urolithiasis2.83081034
7MP0003303_peritoneal_inflammation2.46560380
8MP0003806_abnormal_nucleotide_metabolis2.45407235
9MP0008260_abnormal_autophagy2.39295194
10MP0002139_abnormal_hepatobiliary_system2.36682620
11MP0010352_gastrointestinal_tract_polyps2.30329742
12MP0004858_abnormal_nervous_system2.29992975
13MP0003566_abnormal_cell_adhesion2.08417163
14MP0000678_abnormal_parathyroid_gland2.07179533
15MP0004272_abnormal_basement_membrane1.94604928
16MP0005023_abnormal_wound_healing1.91672073
17MP0005257_abnormal_intraocular_pressure1.83555231
18MP0003191_abnormal_cellular_cholesterol1.79491591
19MP0010234_abnormal_vibrissa_follicle1.78898192
20MP0002796_impaired_skin_barrier1.76144335
21MP0002396_abnormal_hematopoietic_system1.73438454
22MP0005058_abnormal_lysosome_morphology1.73195477
23MP0003300_gastrointestinal_ulcer1.73090586
24MP0006054_spinal_hemorrhage1.72706694
25MP0009278_abnormal_bone_marrow1.66392988
26MP0004233_abnormal_muscle_weight1.66076356
27MP0005076_abnormal_cell_differentiation1.65185109
28MP0005365_abnormal_bile_salt1.56828160
29MP0003436_decreased_susceptibility_to1.56372739
30MP0005623_abnormal_meninges_morphology1.54826249
31MP0005083_abnormal_biliary_tract1.54254668
32MP0003279_aneurysm1.53112902
33MP0002254_reproductive_system_inflammat1.47809815
34MP0000537_abnormal_urethra_morphology1.47361559
35MP0005085_abnormal_gallbladder_physiolo1.40827896
36MP0000003_abnormal_adipose_tissue1.39374521
37MP0010329_abnormal_lipoprotein_level1.36329849
38MP0001730_embryonic_growth_arrest1.33359720
39MP0004957_abnormal_blastocyst_morpholog1.32028952
40MP0003111_abnormal_nucleus_morphology1.31773224
41MP0005409_darkened_coat_color1.31490334
42MP0009333_abnormal_splenocyte_physiolog1.28567214
43MP0005464_abnormal_platelet_physiology1.28264506
44MP0010030_abnormal_orbit_morphology1.27718221
45MP0003693_abnormal_embryo_hatching1.27009988
46MP0000490_abnormal_crypts_of1.24209085
47MP0003172_abnormal_lysosome_physiology1.22307790
48MP0000733_abnormal_muscle_development1.22070811
49MP0000609_abnormal_liver_physiology1.20760950
50MP0001348_abnormal_lacrimal_gland1.19254482
51MP0005397_hematopoietic_system_phenotyp1.18321980
52MP0001545_abnormal_hematopoietic_system1.18321980
53MP0005666_abnormal_adipose_tissue1.16503382
54MP0005375_adipose_tissue_phenotype1.16147403
55MP0008932_abnormal_embryonic_tissue1.13354533
56MP0002249_abnormal_larynx_morphology1.13055986
57MP0002269_muscular_atrophy1.12109435
58MP0000685_abnormal_immune_system1.11147585
59MP0003329_amyloid_beta_deposits1.11009731
60MP0000750_abnormal_muscle_regeneration1.08549296
61MP0000598_abnormal_liver_morphology1.07860197
62MP0001216_abnormal_epidermal_layer1.07534792
63MP0003077_abnormal_cell_cycle1.06055971
64MP0001849_ear_inflammation1.05247078
65MP0005621_abnormal_cell_physiology1.04265350
66MP0005275_abnormal_skin_tensile1.04248900
67MP0001666_abnormal_nutrient_absorption1.03052226
68MP0000465_gastrointestinal_hemorrhage1.02963330
69MP0000858_altered_metastatic_potential1.02918745
70MP0004808_abnormal_hematopoietic_stem1.02288075
71MP0001853_heart_inflammation1.01992629
72MP0001958_emphysema1.01014902
73MP0001915_intracranial_hemorrhage1.00942065
74MP0003252_abnormal_bile_duct0.99755569
75MP0003656_abnormal_erythrocyte_physiolo0.99404111
76MP0004947_skin_inflammation0.98406503
77MP0005319_abnormal_enzyme/_coenzyme0.98250652
78MP0000751_myopathy0.97137389
79MP0004185_abnormal_adipocyte_glucose0.96358066
80MP0001243_abnormal_dermal_layer0.96243021
81MP0000762_abnormal_tongue_morphology0.96012357
82MP0002080_prenatal_lethality0.95304479
83MP0002060_abnormal_skin_morphology0.94516484
84MP0002089_abnormal_postnatal_growth/wei0.94413206
85MP0000467_abnormal_esophagus_morphology0.94202708
86MP0000350_abnormal_cell_proliferation0.94065096
87MP0003091_abnormal_cell_migration0.93036903
88MP0001533_abnormal_skeleton_physiology0.91038367
89MP0008875_abnormal_xenobiotic_pharmacok0.90838378
90MP0004197_abnormal_fetal_growth/weight/0.89958301
91MP0010307_abnormal_tumor_latency0.89418190
92MP0000689_abnormal_spleen_morphology0.89107763
93MP0009643_abnormal_urine_homeostasis0.88400864
94MP0003984_embryonic_growth_retardation0.87852913
95MP0000579_abnormal_nail_morphology0.87333452
96MP0000747_muscle_weakness0.87316428
97MP0002722_abnormal_immune_system0.87265216
98MP0002088_abnormal_embryonic_growth/wei0.87049034
99MP0001661_extended_life_span0.86070155
100MP0008007_abnormal_cellular_replicative0.85921473
101MP0009384_cardiac_valve_regurgitation0.85385129
102MP0000358_abnormal_cell_content/0.84877964
103MP0002086_abnormal_extraembryonic_tissu0.83572508
104MP0000767_abnormal_smooth_muscle0.83395665
105MP0004264_abnormal_extraembryonic_tissu0.83128491
106MP0005025_abnormal_response_to0.82567829
107MP0005332_abnormal_amino_acid0.82394690
108MP0005330_cardiomyopathy0.82068045
109MP0001672_abnormal_embryogenesis/_devel0.82013972
110MP0005380_embryogenesis_phenotype0.82013972
111MP0002019_abnormal_tumor_incidence0.81207834
112MP0002419_abnormal_innate_immunity0.81036682
113MP0005670_abnormal_white_adipose0.81020658
114MP0000477_abnormal_intestine_morphology0.80326973
115MP0010155_abnormal_intestine_physiology0.80042860
116MP0000759_abnormal_skeletal_muscle0.80008158
117MP0003453_abnormal_keratinocyte_physiol0.79880470
118MP0002398_abnormal_bone_marrow0.79570378
119MP0004087_abnormal_muscle_fiber0.79563118
120MP0001697_abnormal_embryo_size0.79194215
121MP0005501_abnormal_skin_physiology0.78993149
122MP0002970_abnormal_white_adipose0.78825680
123MP0009672_abnormal_birth_weight0.78393079
124MP0004510_myositis0.78316228
125MP0008469_abnormal_protein_level0.78014635
126MP0002429_abnormal_blood_cell0.77517383
127MP0002118_abnormal_lipid_homeostasis0.77423808
128MP0000681_abnormal_thyroid_gland0.76729867
129MP0009053_abnormal_anal_canal0.76175331
130MP0001873_stomach_inflammation0.75808328
131MP0003763_abnormal_thymus_physiology0.75691870
132MP0005384_cellular_phenotype0.75418736
133MP0008961_abnormal_basal_metabolism0.75127917
134MP0004782_abnormal_surfactant_physiolog0.75084566
135MP0002998_abnormal_bone_remodeling0.74844850
136MP0002933_joint_inflammation0.74547965
137MP0000604_amyloidosis0.74530032
138MP0000313_abnormal_cell_death0.74182459
139MP0003186_abnormal_redox_activity0.73632747
140MP0009931_abnormal_skin_appearance0.73385406
141MP0003448_altered_tumor_morphology0.73067947
142MP0010094_abnormal_chromosome_stability0.71028178
143MP0003315_abnormal_perineum_morphology0.70167423

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)4.70678915
2Premature rupture of membranes (HP:0001788)3.82250566
3Cerebral aneurysm (HP:0004944)3.47191015
4Peritonitis (HP:0002586)3.24371984
5Deep venous thrombosis (HP:0002625)3.07258842
6Distal lower limb amyotrophy (HP:0008944)2.94988857
7Upper limb amyotrophy (HP:0009129)2.94396273
8Distal upper limb amyotrophy (HP:0007149)2.94396273
9Cervical subluxation (HP:0003308)2.83282937
10Xanthomatosis (HP:0000991)2.79215061
11Abnormality of the Achilles tendon (HP:0005109)2.75812734
12Achilles tendon contracture (HP:0001771)2.72467577
13Shallow orbits (HP:0000586)2.68364936
14Biconcave vertebral bodies (HP:0004586)2.67850241
15Hand muscle atrophy (HP:0009130)2.66294764
16Thrombocytosis (HP:0001894)2.63413333
17Ankle contracture (HP:0006466)2.62990060
18Ulnar bowing (HP:0003031)2.62048173
19Spinal rigidity (HP:0003306)2.55390361
20Vertebral compression fractures (HP:0002953)2.53775079
21Stridor (HP:0010307)2.50012319
22Increased connective tissue (HP:0009025)2.47186696
23Nonimmune hydrops fetalis (HP:0001790)2.44693342
24Spastic diplegia (HP:0001264)2.43169229
25Long palpebral fissure (HP:0000637)2.39764833
26Centrally nucleated skeletal muscle fibers (HP:0003687)2.36633335
27Distal lower limb muscle weakness (HP:0009053)2.34329465
28Abnormality of monocarboxylic acid metabolism (HP:0010996)2.32596566
29Increased serum ferritin (HP:0003281)2.31134997
30Elbow flexion contracture (HP:0002987)2.28305332
31Premature skin wrinkling (HP:0100678)2.28255590
32Insomnia (HP:0100785)2.28204193
33Increased density of long bones (HP:0006392)2.27404491
34Short nail (HP:0001799)2.24897957
35Increased mean platelet volume (HP:0011877)2.24257129
36Abnormality of cells of the erythroid lineage (HP:0012130)2.24013545
37Broad distal phalanx of finger (HP:0009836)2.21743122
38Abnormal platelet volume (HP:0011876)2.19467464
39Hyperacusis (HP:0010780)2.19116607
40Genu recurvatum (HP:0002816)2.18816521
41Abnormality of the distal phalanges of the toes (HP:0010182)2.17957698
42Abnormal number of erythroid precursors (HP:0012131)2.17647409
43Increased variability in muscle fiber diameter (HP:0003557)2.16443163
44Aortic dissection (HP:0002647)2.14782627
45Selective tooth agenesis (HP:0001592)2.14001353
46Impaired platelet aggregation (HP:0003540)2.12118259
47Abnormal platelet function (HP:0011869)2.12118259
48Multiple enchondromatosis (HP:0005701)2.10085914
49Difficulty climbing stairs (HP:0003551)2.09486397
50Mitral valve prolapse (HP:0001634)2.09090512
51Dilatation of the ascending aorta (HP:0005111)2.08514437
52Abnormality of the peritoneum (HP:0002585)2.08195686
53Abnormality of iron homeostasis (HP:0011031)2.05183185
54Myocardial infarction (HP:0001658)2.05109200
55Bladder diverticulum (HP:0000015)2.03973119
56Blue sclerae (HP:0000592)2.03906640
57Aneurysm (HP:0002617)2.03568924
58Slender long bone (HP:0003100)2.03483060
59Thin bony cortex (HP:0002753)2.03049511
60Dysostosis multiplex (HP:0000943)2.00518003
61Ragged-red muscle fibers (HP:0003200)1.99517820
62Natal tooth (HP:0000695)1.99223249
63Polygenic inheritance (HP:0010982)1.98667566
64Abnormality of skeletal muscle fiber size (HP:0012084)1.98539036
65Back pain (HP:0003418)1.98168716
66Lower limb amyotrophy (HP:0007210)1.95191533
67Reticulocytopenia (HP:0001896)1.94400361
68Gastrointestinal dysmotility (HP:0002579)1.92564228
69Lymphangioma (HP:0100764)1.92371056
70Flat acetabular roof (HP:0003180)1.92339043
71Myopathic facies (HP:0002058)1.90888216
72Aortic aneurysm (HP:0004942)1.90451463
73Wormian bones (HP:0002645)1.90018828
74Abnormality of aromatic amino acid family metabolism (HP:0004338)1.89814100
75Trismus (HP:0000211)1.88641142
76Mesangial abnormality (HP:0001966)1.88490429
77Mildly elevated creatine phosphokinase (HP:0008180)1.88371641
78Nasal polyposis (HP:0100582)1.87872160
79Reduced subcutaneous adipose tissue (HP:0003758)1.85890064
80Ulnar deviation of the wrist (HP:0003049)1.85401884
81Generalized amyotrophy (HP:0003700)1.85106215
82Abnormality of the umbilical cord (HP:0010881)1.85074986
83Patellar dislocation (HP:0002999)1.84990925
84Neonatal death (HP:0003811)1.83910088
85Upper motor neuron abnormality (HP:0002127)1.83278882
86Rough bone trabeculation (HP:0100670)1.83112425
87Cholecystitis (HP:0001082)1.83062847
88Abnormal gallbladder physiology (HP:0012438)1.83062847
89Abnormality of the calcaneus (HP:0008364)1.82875883
90Abnormality of the nasal mucosa (HP:0000433)1.82822432
91Abnormality of transition element cation homeostasis (HP:0011030)1.82222667
92Bowed forearm bones (HP:0003956)1.82162366
93Bowing of the arm (HP:0006488)1.82162366
94Increased cerebral lipofuscin (HP:0011813)1.80901656
95Abnormal ossification of hand bones (HP:0005921)1.80126496
96Mucopolysacchariduria (HP:0008155)1.79898354
97Urinary glycosaminoglycan excretion (HP:0003541)1.79898354
98Abnormality of reticulocytes (HP:0004312)1.78317892
99Abnormality of pyrimidine metabolism (HP:0004353)1.78185305
100Abnormality of the distal phalanx of the thumb (HP:0009617)1.77216761
101Fragile skin (HP:0001030)1.76693045
102Osteolytic defects of the hand bones (HP:0009699)1.76342078
103Osteolytic defects of the phalanges of the hand (HP:0009771)1.76342078
104Abnormality of complement system (HP:0005339)1.75108832
105Abnormality of oral frenula (HP:0000190)1.75064562
106Mitral regurgitation (HP:0001653)1.74924724
107Disproportionate tall stature (HP:0001519)1.74270739
108Cellulitis (HP:0100658)1.73262653
109Abnormality of carpal bone ossification (HP:0006257)1.73149183
110Chondrocalcinosis (HP:0000934)1.73007404
111J-shaped sella turcica (HP:0002680)1.72465031
112Short clavicles (HP:0000894)1.72424585
113Interstitial pulmonary disease (HP:0006530)1.72097180
114Hypobetalipoproteinemia (HP:0003563)1.71811473
115Late onset (HP:0003584)1.71533940
116Fragile nails (HP:0001808)1.71306748
117Hypertensive crisis (HP:0100735)1.71289370
118Hemorrhage of the eye (HP:0011885)1.70114469
119Pseudobulbar signs (HP:0002200)1.69808936
120Joint stiffness (HP:0001387)1.69513312
121Abnormality of glycolipid metabolism (HP:0010969)1.69351557
122Abnormality of liposaccharide metabolism (HP:0010968)1.69351557
123Abnormality of glycosphingolipid metabolism (HP:0004343)1.69351557
124Reticulocytosis (HP:0001923)1.69271504
125Slender build (HP:0001533)1.69205016
126Pustule (HP:0200039)1.68969343
127Increased neuronal autofluorescent lipopigment (HP:0002074)1.68697333
128Syringomyelia (HP:0003396)1.67333814
129Spinal cord lesions (HP:0100561)1.67333814
130Broad face (HP:0000283)1.66396068
131Intrahepatic cholestasis (HP:0001406)1.65901527
132Abnormal cartilage morphology (HP:0002763)1.64884137
133Ankyloglossia (HP:0010296)1.64733624
134Ectopia lentis (HP:0001083)1.64593930
135Broad metatarsal (HP:0001783)1.64480575
136Abnormality of the acetabulum (HP:0003170)1.64420532
137Atrophic scars (HP:0001075)1.63671989
138Petechiae (HP:0000967)1.63442956
139Advanced eruption of teeth (HP:0006288)1.63366270
140Obstructive sleep apnea (HP:0002870)1.61898835
141Milia (HP:0001056)1.61671947
142Truncus arteriosus (HP:0001660)1.60916013
143Epistaxis (HP:0000421)1.60651243
144Hyperammonemia (HP:0001987)1.59795555
145Abnormality of the thoracic spine (HP:0100711)1.59654566
146Progressive muscle weakness (HP:0003323)1.59518085
147Bowel diverticulosis (HP:0005222)1.59361092
148Hyperparathyroidism (HP:0000843)1.59332716
149Renal duplication (HP:0000075)1.59118809
150Ileus (HP:0002595)1.59080571
151Hallux valgus (HP:0001822)1.58751902
152Thoracic kyphosis (HP:0002942)1.58210491
153Aplasia/Hypoplasia of the clavicles (HP:0006710)1.57682266
154Pointed chin (HP:0000307)1.57416594
155Abnormality of polysaccharide metabolism (HP:0011012)1.56854443
156Abnormality of glycosaminoglycan metabolism (HP:0004371)1.56854443
157Abnormality of mucopolysaccharide metabolism (HP:0011020)1.56854443
158Bulbar palsy (HP:0001283)1.56813289
159Axonal loss (HP:0003447)1.56776586
160Nail dystrophy (HP:0008404)1.56664645

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SMG14.74351307
2TRIB34.72734791
3PKN24.11959731
4ERN13.92537170
5EEF2K3.28537150
6IRAK33.12312800
7MAP3K102.88080670
8TTN2.84890040
9PRPF4B2.79026485
10MAP4K12.32766379
11TESK21.95957663
12LRRK21.89447709
13PTK61.81381721
14BCKDK1.77668880
15NME21.76658248
16STK101.74040982
17SIK11.71880308
18MST1R1.68720486
19VRK21.67138497
20SCYL21.64285230
21BMX1.59369794
22PAK41.57270604
23RPS6KA41.52190904
24ARAF1.52181302
25PRKD31.49613072
26EPHB11.45295269
27MAP3K111.45129618
28ICK1.42555852
29CDK121.40722280
30FGFR41.34975659
31KDR1.34852210
32MAP2K31.33897997
33EPHA21.29432874
34MAP3K81.23545296
35GRK61.20841043
36BLK1.20366868
37PDGFRA1.19760816
38TESK11.19497964
39RIPK11.18369028
40PIM21.14905967
41TYK21.12534642
42PAK21.08092848
43ZAP701.07990252
44MTOR1.05053638
45TSSK61.04277776
46DDR21.02597843
47PRKD21.02104674
48CDK41.01059267
49RPS6KB21.00166448
50NEK20.99316626
51MAP2K20.96843676
52BRAF0.95534994
53FLT30.95309093
54NEK10.92630246
55TLK10.91302839
56LMTK20.90560403
57ALK0.89714692
58MAP3K130.88535294
59BUB10.87832154
60TBK10.85805173
61BTK0.82934761
62TGFBR20.82583112
63IRAK20.82186417
64KSR20.81564916
65PTK20.80636906
66CDK70.79732996
67TAF10.79162421
68NTRK10.78781457
69CDC42BPA0.78727785
70CSK0.76177716
71MAP3K10.75384876
72TAOK10.74835327
73PAK10.73653178
74MAPKAPK30.73450776
75MET0.72956257
76ILK0.70451910
77CDC70.69951049
78MAPK110.69239608
79RPS6KC10.68070386
80RPS6KL10.68070386
81RPS6KA60.67990921
82KIT0.67076543
83RPS6KA20.66777690
84PDPK10.65707723
85CSF1R0.63012291
86ABL20.62116840
87JAK30.60183290
88MARK20.59074421
89HCK0.57068982
90DAPK10.56681983
91MAP3K60.55844245
92EIF2AK10.55572719
93CDK80.55337861
94TTK0.53701182
95WEE10.52500213
96PIM10.50910588
97FES0.50245509
98PASK0.49624343
99CDK90.49616008
100EPHB20.49173444
101HIPK20.48134735
102CHEK20.48093246
103MATK0.47571708
104AKT20.47124519
105MAPKAPK20.46677530
106JAK20.44137248
107DYRK1B0.43884727
108IRAK40.42316040
109LIMK10.41519962
110DAPK30.41386288
111MOS0.41286862
112ITK0.41079248
113AURKA0.40659457
114LATS10.40353548
115LATS20.40274683
116TAOK20.40214223
117AURKB0.39465987
118ATR0.38933754
119MELK0.38636353
120CAMK1D0.38355853
121STK40.38093809
122CHEK10.37949556
123CDK60.37805444
124CLK10.37719112
125MAP3K140.37009130
126PRKCI0.36971227
127MAP3K70.36527800
128PRKG20.36509040
129RPS6KA10.35915383
130MAP3K30.35052402
131MAPK40.34985322
132BRSK10.34366295
133PRKD10.34049867

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030302.96757307
2One carbon pool by folate_Homo sapiens_hsa006702.61154965
3Sulfur relay system_Homo sapiens_hsa041222.22026461
42-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.16194111
5Selenocompound metabolism_Homo sapiens_hsa004502.05436720
6Biosynthesis of amino acids_Homo sapiens_hsa012302.04981762
7Ribosome_Homo sapiens_hsa030102.01943342
8Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.92126130
9Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.90464675
10Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.86156950
11Cyanoamino acid metabolism_Homo sapiens_hsa004601.83963467
12Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.78932644
13Pentose phosphate pathway_Homo sapiens_hsa000301.77936415
14Carbon metabolism_Homo sapiens_hsa012001.65502458
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.61140909
16Primary bile acid biosynthesis_Homo sapiens_hsa001201.60779917
17Fatty acid degradation_Homo sapiens_hsa000711.53477200
18Non-small cell lung cancer_Homo sapiens_hsa052231.51784747
19Drug metabolism - other enzymes_Homo sapiens_hsa009831.51023996
20Pancreatic cancer_Homo sapiens_hsa052121.46393998
21Nitrogen metabolism_Homo sapiens_hsa009101.43596914
22Arginine biosynthesis_Homo sapiens_hsa002201.41826145
23Thyroid cancer_Homo sapiens_hsa052161.38273263
24Folate biosynthesis_Homo sapiens_hsa007901.36462090
25Lysine degradation_Homo sapiens_hsa003101.35482345
26Prion diseases_Homo sapiens_hsa050201.32682268
27Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.29904917
28Galactose metabolism_Homo sapiens_hsa000521.26305528
29Cysteine and methionine metabolism_Homo sapiens_hsa002701.25440266
30Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.24872425
31Base excision repair_Homo sapiens_hsa034101.23903944
32Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.23458558
33Glycosaminoglycan degradation_Homo sapiens_hsa005311.21165225
34Complement and coagulation cascades_Homo sapiens_hsa046101.16726663
35Mismatch repair_Homo sapiens_hsa034301.16691408
36Fat digestion and absorption_Homo sapiens_hsa049751.15683178
37Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.15257793
38Spliceosome_Homo sapiens_hsa030401.14062474
39Pentose and glucuronate interconversions_Homo sapiens_hsa000401.13373504
40Other glycan degradation_Homo sapiens_hsa005111.13130014
41Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.10786260
42Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.10517402
43Vitamin B6 metabolism_Homo sapiens_hsa007501.09580668
44Tryptophan metabolism_Homo sapiens_hsa003801.08357557
45Chronic myeloid leukemia_Homo sapiens_hsa052201.08015271
46Staphylococcus aureus infection_Homo sapiens_hsa051501.07146352
47Bladder cancer_Homo sapiens_hsa052191.06695603
48Endometrial cancer_Homo sapiens_hsa052131.06331531
49Vibrio cholerae infection_Homo sapiens_hsa051101.05721703
50PPAR signaling pathway_Homo sapiens_hsa033200.99455356
51Caffeine metabolism_Homo sapiens_hsa002320.98458518
52Central carbon metabolism in cancer_Homo sapiens_hsa052300.97271697
53Neurotrophin signaling pathway_Homo sapiens_hsa047220.96460840
54Fructose and mannose metabolism_Homo sapiens_hsa000510.95929741
55Arginine and proline metabolism_Homo sapiens_hsa003300.94936987
56Fatty acid metabolism_Homo sapiens_hsa012120.93475368
57Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.93457427
58Acute myeloid leukemia_Homo sapiens_hsa052210.93295914
59N-Glycan biosynthesis_Homo sapiens_hsa005100.90377492
60Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.90108530
61Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.89092610
62Pyruvate metabolism_Homo sapiens_hsa006200.89054701
63Insulin signaling pathway_Homo sapiens_hsa049100.86770110
64Small cell lung cancer_Homo sapiens_hsa052220.86024049
65RNA transport_Homo sapiens_hsa030130.85899257
66Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.85555048
67Glioma_Homo sapiens_hsa052140.85406951
68Thyroid hormone signaling pathway_Homo sapiens_hsa049190.81785544
69Notch signaling pathway_Homo sapiens_hsa043300.81557258
70Glutathione metabolism_Homo sapiens_hsa004800.81251993
71Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80822331
72Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.79238022
73Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.78902263
74Hepatitis C_Homo sapiens_hsa051600.78651244
75Starch and sucrose metabolism_Homo sapiens_hsa005000.77640807
76ABC transporters_Homo sapiens_hsa020100.77202074
77Shigellosis_Homo sapiens_hsa051310.76191906
78Pyrimidine metabolism_Homo sapiens_hsa002400.75820925
79Colorectal cancer_Homo sapiens_hsa052100.75186923
80Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.74760431
81Lysosome_Homo sapiens_hsa041420.74586317
82Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.74235243
83Renal cell carcinoma_Homo sapiens_hsa052110.73817696
84Salmonella infection_Homo sapiens_hsa051320.73121462
85Antigen processing and presentation_Homo sapiens_hsa046120.73031521
86Leishmaniasis_Homo sapiens_hsa051400.72244194
87Apoptosis_Homo sapiens_hsa042100.72103763
88Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.71008602
89Bile secretion_Homo sapiens_hsa049760.70773392
90ErbB signaling pathway_Homo sapiens_hsa040120.70359346
91p53 signaling pathway_Homo sapiens_hsa041150.68576063
92AMPK signaling pathway_Homo sapiens_hsa041520.67780988
93Prostate cancer_Homo sapiens_hsa052150.67086196
94Longevity regulating pathway - mammal_Homo sapiens_hsa042110.65723978
95Insulin resistance_Homo sapiens_hsa049310.65458411
96Toll-like receptor signaling pathway_Homo sapiens_hsa046200.65299840
97Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.65292275
98Osteoclast differentiation_Homo sapiens_hsa043800.65169207
99Viral carcinogenesis_Homo sapiens_hsa052030.64983652
100Toxoplasmosis_Homo sapiens_hsa051450.63396964
101Leukocyte transendothelial migration_Homo sapiens_hsa046700.62974324
102Cell cycle_Homo sapiens_hsa041100.62918150
103Renin-angiotensin system_Homo sapiens_hsa046140.62569609
104Proteoglycans in cancer_Homo sapiens_hsa052050.61895867
105beta-Alanine metabolism_Homo sapiens_hsa004100.60667944
106Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.60330999
107Endocytosis_Homo sapiens_hsa041440.60323269
108Epstein-Barr virus infection_Homo sapiens_hsa051690.59333904
109Adherens junction_Homo sapiens_hsa045200.58795308
110Legionellosis_Homo sapiens_hsa051340.58427159
111Peroxisome_Homo sapiens_hsa041460.57442758
112Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.57339796
113HTLV-I infection_Homo sapiens_hsa051660.57073260
114Regulation of actin cytoskeleton_Homo sapiens_hsa048100.56948947
115Histidine metabolism_Homo sapiens_hsa003400.56778696
116TNF signaling pathway_Homo sapiens_hsa046680.56125068
117Focal adhesion_Homo sapiens_hsa045100.55914081
118Influenza A_Homo sapiens_hsa051640.52529442
119Nucleotide excision repair_Homo sapiens_hsa034200.52249410
120Sphingolipid signaling pathway_Homo sapiens_hsa040710.52214205
121mRNA surveillance pathway_Homo sapiens_hsa030150.51533678
122Adipocytokine signaling pathway_Homo sapiens_hsa049200.50951395
123HIF-1 signaling pathway_Homo sapiens_hsa040660.48894450
124Amoebiasis_Homo sapiens_hsa051460.48729476
125B cell receptor signaling pathway_Homo sapiens_hsa046620.48657005
126Herpes simplex infection_Homo sapiens_hsa051680.46857115
127Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.46647088
128Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.46576561
129ECM-receptor interaction_Homo sapiens_hsa045120.46167611
130Sulfur metabolism_Homo sapiens_hsa009200.45543091
131Phospholipase D signaling pathway_Homo sapiens_hsa040720.45534312
132VEGF signaling pathway_Homo sapiens_hsa043700.45410391
133Melanoma_Homo sapiens_hsa052180.44941292
134Hepatitis B_Homo sapiens_hsa051610.44121105
135RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.44084215
136MicroRNAs in cancer_Homo sapiens_hsa052060.43491805
137AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.43465110
138GnRH signaling pathway_Homo sapiens_hsa049120.43379934
139Basal cell carcinoma_Homo sapiens_hsa052170.42604222
140mTOR signaling pathway_Homo sapiens_hsa041500.42139043
141Propanoate metabolism_Homo sapiens_hsa006400.41574464
142Glycerolipid metabolism_Homo sapiens_hsa005610.41166301

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