Rank | Gene Set | Z-score |
---|---|---|
1 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.94402705 |
2 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.72734883 |
3 | endothelial cell chemotaxis (GO:0035767) | 3.63104082 |
4 | plasma membrane repair (GO:0001778) | 3.58757688 |
5 | mannose metabolic process (GO:0006013) | 3.46671173 |
6 | positive regulation of histone deacetylation (GO:0031065) | 3.35864939 |
7 | activation of Rac GTPase activity (GO:0032863) | 3.33759829 |
8 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 3.29795879 |
9 | negative regulation of cell size (GO:0045792) | 3.29748691 |
10 | atrioventricular valve morphogenesis (GO:0003181) | 3.27300096 |
11 | cell-cell junction maintenance (GO:0045217) | 3.25897802 |
12 | apoptotic cell clearance (GO:0043277) | 3.24281067 |
13 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.23702007 |
14 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 3.21513411 |
15 | protein heterotrimerization (GO:0070208) | 3.17585761 |
16 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.14743819 |
17 | stress fiber assembly (GO:0043149) | 3.14184540 |
18 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 3.12855316 |
19 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.08559940 |
20 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.06422812 |
21 | axon extension involved in axon guidance (GO:0048846) | 3.06422812 |
22 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 3.03988282 |
23 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.03735296 |
24 | adherens junction assembly (GO:0034333) | 3.03307131 |
25 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.99266968 |
26 | sodium ion export (GO:0071436) | 2.98629812 |
27 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.92746558 |
28 | cell-substrate junction assembly (GO:0007044) | 2.91469787 |
29 | establishment of nucleus localization (GO:0040023) | 2.91458007 |
30 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.91023142 |
31 | positive regulation of receptor recycling (GO:0001921) | 2.90192994 |
32 | negative regulation of fatty acid transport (GO:2000192) | 2.86689339 |
33 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.85629342 |
34 | barbed-end actin filament capping (GO:0051016) | 2.85473598 |
35 | peptidyl-lysine dimethylation (GO:0018027) | 2.83667117 |
36 | NLS-bearing protein import into nucleus (GO:0006607) | 2.82388837 |
37 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.77747216 |
38 | response to laminar fluid shear stress (GO:0034616) | 2.76836472 |
39 | anatomical structure regression (GO:0060033) | 2.75773846 |
40 | gonadal mesoderm development (GO:0007506) | 2.74632351 |
41 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.73199720 |
42 | protein retention in ER lumen (GO:0006621) | 2.72467483 |
43 | establishment of apical/basal cell polarity (GO:0035089) | 2.72399857 |
44 | regulation of extracellular matrix disassembly (GO:0010715) | 2.71468782 |
45 | activation of MAPKKK activity (GO:0000185) | 2.71265854 |
46 | regulation of p38MAPK cascade (GO:1900744) | 2.70155602 |
47 | polarized epithelial cell differentiation (GO:0030859) | 2.68862761 |
48 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.68219567 |
49 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.63754083 |
50 | cardiac myofibril assembly (GO:0055003) | 2.62996163 |
51 | cell-substrate adherens junction assembly (GO:0007045) | 2.62363932 |
52 | focal adhesion assembly (GO:0048041) | 2.62363932 |
53 | hippo signaling (GO:0035329) | 2.61694897 |
54 | cell volume homeostasis (GO:0006884) | 2.59384480 |
55 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.58961280 |
56 | pre-miRNA processing (GO:0031054) | 2.58435054 |
57 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 2.58166675 |
58 | COPI coating of Golgi vesicle (GO:0048205) | 2.57692677 |
59 | Golgi transport vesicle coating (GO:0048200) | 2.57692677 |
60 | hemidesmosome assembly (GO:0031581) | 2.57202425 |
61 | desmosome organization (GO:0002934) | 2.57057410 |
62 | epithelial cell fate commitment (GO:0072148) | 2.56312787 |
63 | regulation of ARF GTPase activity (GO:0032312) | 2.56026360 |
64 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.55767672 |
65 | protein localization to endosome (GO:0036010) | 2.55679312 |
66 | endodermal cell differentiation (GO:0035987) | 2.54555962 |
67 | semaphorin-plexin signaling pathway (GO:0071526) | 2.53528330 |
68 | layer formation in cerebral cortex (GO:0021819) | 2.53505033 |
69 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.52792999 |
70 | stress granule assembly (GO:0034063) | 2.52276772 |
71 | neural tube development (GO:0021915) | 2.51592406 |
72 | cell communication by electrical coupling (GO:0010644) | 2.46267270 |
73 | coronary vasculature morphogenesis (GO:0060977) | 2.46132185 |
74 | positive regulation of glycogen biosynthetic process (GO:0045725) | 2.45782484 |
75 | negative regulation of myotube differentiation (GO:0010832) | 2.45421476 |
76 | protein targeting to plasma membrane (GO:0072661) | 2.43321136 |
77 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.43041702 |
78 | embryonic eye morphogenesis (GO:0048048) | 2.42347472 |
79 | negative regulation of catenin import into nucleus (GO:0035414) | 2.42334603 |
80 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.41789403 |
81 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.41387729 |
82 | activation of JUN kinase activity (GO:0007257) | 2.40411504 |
83 | negative regulation of smooth muscle cell migration (GO:0014912) | 2.39207037 |
84 | heterochromatin organization (GO:0070828) | 2.39186383 |
85 | modulation by virus of host morphology or physiology (GO:0019048) | 2.39073320 |
86 | apoptotic process involved in morphogenesis (GO:0060561) | 2.38933267 |
87 | maternal placenta development (GO:0001893) | 2.38911694 |
88 | endocytic recycling (GO:0032456) | 2.38533486 |
89 | regulation of clathrin-mediated endocytosis (GO:2000369) | 2.37398723 |
90 | cortical actin cytoskeleton organization (GO:0030866) | 2.37227695 |
91 | actin filament bundle organization (GO:0061572) | 2.37009676 |
92 | actin filament bundle assembly (GO:0051017) | 2.37009676 |
93 | embryonic foregut morphogenesis (GO:0048617) | 2.36880570 |
94 | cell migration involved in heart development (GO:0060973) | 2.36609596 |
95 | myoblast fusion (GO:0007520) | 2.36016539 |
96 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 2.35781138 |
97 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.35778569 |
98 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.34474955 |
99 | modulation by symbiont of host cellular process (GO:0044068) | 2.34443683 |
100 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.34275554 |
101 | glomerular basement membrane development (GO:0032836) | 2.33537035 |
102 | positive regulation of protein deacetylation (GO:0090312) | 2.33467147 |
103 | epithelial cell-cell adhesion (GO:0090136) | 2.33363108 |
104 | positive regulation of protein dephosphorylation (GO:0035307) | 2.33315459 |
105 | response to fluid shear stress (GO:0034405) | 2.32301851 |
106 | basement membrane organization (GO:0071711) | 2.31697937 |
107 | cell junction maintenance (GO:0034331) | 2.31441684 |
108 | regulation of endothelial cell chemotaxis (GO:2001026) | 2.31229622 |
109 | syncytium formation by plasma membrane fusion (GO:0000768) | 2.31218107 |
110 | regulation of histone H3-K27 methylation (GO:0061085) | 2.30919652 |
111 | locomotory exploration behavior (GO:0035641) | 2.30785109 |
112 | collagen fibril organization (GO:0030199) | 2.30590164 |
113 | apoptotic process involved in development (GO:1902742) | 2.29262358 |
114 | convergent extension (GO:0060026) | 2.29187478 |
115 | embryonic process involved in female pregnancy (GO:0060136) | 2.28866857 |
116 | establishment of monopolar cell polarity (GO:0061162) | 2.28752305 |
117 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.28752305 |
118 | growth hormone secretion (GO:0030252) | 2.28299858 |
119 | eye morphogenesis (GO:0048592) | 2.27971053 |
120 | cardiac muscle cell proliferation (GO:0060038) | 2.27613598 |
121 | endothelial cell morphogenesis (GO:0001886) | 2.27231330 |
122 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.27100818 |
123 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.26764370 |
124 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.26730419 |
125 | * heart morphogenesis (GO:0003007) | 2.26684727 |
126 | synaptic vesicle maturation (GO:0016188) | 2.26665310 |
127 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.26452876 |
128 | venous blood vessel morphogenesis (GO:0048845) | 2.26426377 |
129 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.25961773 |
130 | regulation of establishment of planar polarity (GO:0090175) | 2.25468918 |
131 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 2.25122847 |
132 | bone trabecula formation (GO:0060346) | 2.25019125 |
133 | regulation of hippo signaling (GO:0035330) | 2.24888940 |
134 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.24830698 |
135 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.24787481 |
136 | regulation of fatty acid beta-oxidation (GO:0031998) | 2.24340844 |
137 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition | 2.23470639 |
138 | embryonic camera-type eye morphogenesis (GO:0048596) | 2.23162051 |
139 | skin morphogenesis (GO:0043589) | 2.22589610 |
140 | negative regulation of glial cell proliferation (GO:0060253) | 2.21586917 |
141 | regulation of early endosome to late endosome transport (GO:2000641) | 2.21200814 |
142 | response to muramyl dipeptide (GO:0032495) | 2.20180713 |
143 | regulation of ARF protein signal transduction (GO:0032012) | 2.20162951 |
144 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.19270980 |
145 | heparan sulfate proteoglycan metabolic process (GO:0030201) | 2.18736471 |
146 | corticosteroid receptor signaling pathway (GO:0031958) | 2.18721228 |
147 | glial cell proliferation (GO:0014009) | 2.18289003 |
148 | Rho protein signal transduction (GO:0007266) | 2.18167644 |
149 | camera-type eye morphogenesis (GO:0048593) | 2.18035098 |
150 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.17501025 |
151 | collecting duct development (GO:0072044) | 2.16284459 |
152 | syncytium formation (GO:0006949) | 2.15318724 |
153 | receptor catabolic process (GO:0032801) | 2.15286695 |
154 | positive regulation of osteoblast proliferation (GO:0033690) | 2.15002230 |
155 | renal filtration (GO:0097205) | 2.13781391 |
156 | blood vessel endothelial cell migration (GO:0043534) | 2.13373155 |
157 | negative regulation of nucleotide catabolic process (GO:0030812) | 2.13155916 |
158 | gastrulation with mouth forming second (GO:0001702) | 2.11821216 |
159 | regulation of tight junction assembly (GO:2000810) | 2.11669618 |
160 | adherens junction organization (GO:0034332) | 2.11629388 |
161 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 2.11567099 |
162 | signal complex assembly (GO:0007172) | 2.11324046 |
163 | cortical cytoskeleton organization (GO:0030865) | 2.10830433 |
164 | heparan sulfate proteoglycan biosynthetic process (GO:0015012) | 2.10601758 |
165 | positive regulation of fibroblast migration (GO:0010763) | 2.10204490 |
166 | positive regulation of p38MAPK cascade (GO:1900745) | 2.10188093 |
167 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 2.09017972 |
168 | placenta blood vessel development (GO:0060674) | 2.07512703 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.19947583 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.00031682 |
3 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.94773918 |
4 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.79147467 |
5 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.69829299 |
6 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.56340233 |
7 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.41504899 |
8 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 2.37856874 |
9 | * KDM2B_26808549_Chip-Seq_K562_Human | 2.28427433 |
10 | * MYC_22102868_ChIP-Seq_BL_Human | 2.27604112 |
11 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 2.27263417 |
12 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.17852767 |
13 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 2.17575962 |
14 | * ZFP281_27345836_Chip-Seq_ESCs_Mouse | 2.11136136 |
15 | * LXR_22292898_ChIP-Seq_THP-1_Human | 2.10715772 |
16 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 2.09216595 |
17 | * TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 2.06869351 |
18 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 2.06356106 |
19 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.03204452 |
20 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 2.02451959 |
21 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.02285201 |
22 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.00449569 |
23 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.99253536 |
24 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.95562942 |
25 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.95503367 |
26 | * DROSHA_22980978_ChIP-Seq_HELA_Human | 1.77174414 |
27 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.75120930 |
28 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.74239448 |
29 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.72992995 |
30 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.72740003 |
31 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.71672146 |
32 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.68669060 |
33 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.67865306 |
34 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.64397154 |
35 | * VDR_21846776_ChIP-Seq_THP-1_Human | 1.62751370 |
36 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.59626767 |
37 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.49152495 |
38 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.49087405 |
39 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.49074296 |
40 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.47065570 |
41 | * VDR_24763502_ChIP-Seq_THP-1_Human | 1.46959343 |
42 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.45161992 |
43 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.41833230 |
44 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.41408775 |
45 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.40490318 |
46 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.39686947 |
47 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.37746698 |
48 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.37082084 |
49 | * RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.35089109 |
50 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.34880340 |
51 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.33196199 |
52 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.31714463 |
53 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.31714463 |
54 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.31342305 |
55 | * RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.29813611 |
56 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.28403118 |
57 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.28403118 |
58 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.27482963 |
59 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.26294076 |
60 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.26138021 |
61 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.25423601 |
62 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.25349485 |
63 | * NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.25136312 |
64 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.24247028 |
65 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.23542883 |
66 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.23192124 |
67 | * SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.23130436 |
68 | * SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.18573376 |
69 | ATF3_27146783_Chip-Seq_COLON_Human | 1.16900785 |
70 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.16745148 |
71 | * VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.16303658 |
72 | SPI1_23127762_ChIP-Seq_K562_Human | 1.15327589 |
73 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.15299352 |
74 | * SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.15179163 |
75 | * TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.15047427 |
76 | * TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.13984467 |
77 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.12837997 |
78 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.11622831 |
79 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.10941178 |
80 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.10768025 |
81 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.09447695 |
82 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.07722122 |
83 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.07317690 |
84 | * FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.06711240 |
85 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.06427883 |
86 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.06409000 |
87 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.05290214 |
88 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.05148873 |
89 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.04819773 |
90 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.04732440 |
91 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.04676171 |
92 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.04675685 |
93 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.03556608 |
94 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.03483001 |
95 | * SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.03440484 |
96 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.03156015 |
97 | * NCOR1_26117541_ChIP-Seq_K562_Human | 1.01935896 |
98 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.01567858 |
99 | * CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.00976710 |
100 | P68_20966046_ChIP-Seq_HELA_Human | 1.00802195 |
101 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.00241142 |
102 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.00112473 |
103 | UTX_26944678_Chip-Seq_JUKART_Human | 1.00099553 |
104 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.99209566 |
105 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.98912213 |
106 | * HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.98677387 |
107 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.98614037 |
108 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.98503116 |
109 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.98258286 |
110 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.97672386 |
111 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.97422860 |
112 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.96049396 |
113 | MAF_26560356_Chip-Seq_TH1_Human | 0.95448766 |
114 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.95415908 |
115 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.95308567 |
116 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.95162477 |
117 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.94756344 |
118 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.94172273 |
119 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.93783926 |
120 | * NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.93681432 |
121 | * NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.93393453 |
122 | MAF_26560356_Chip-Seq_TH2_Human | 0.93026905 |
123 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.92455225 |
124 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.92205209 |
125 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.91457259 |
126 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.90955276 |
127 | GATA1_19941826_ChIP-Seq_K562_Human | 0.90768123 |
128 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.90527914 |
129 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.89577188 |
130 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.89512284 |
131 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.87716423 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 4.26178230 |
2 | MP0008438_abnormal_cutaneous_collagen | 3.25503421 |
3 | MP0005623_abnormal_meninges_morphology | 3.03206895 |
4 | MP0000751_myopathy | 2.63835306 |
5 | MP0005409_darkened_coat_color | 2.45604975 |
6 | MP0003283_abnormal_digestive_organ | 2.42363067 |
7 | MP0008961_abnormal_basal_metabolism | 2.40671702 |
8 | MP0005058_abnormal_lysosome_morphology | 2.32089416 |
9 | MP0004858_abnormal_nervous_system | 2.26758788 |
10 | MP0009278_abnormal_bone_marrow | 2.22974562 |
11 | MP0003045_fibrosis | 2.14646809 |
12 | MP0000733_abnormal_muscle_development | 2.14080318 |
13 | MP0003566_abnormal_cell_adhesion | 2.11121209 |
14 | * MP0005076_abnormal_cell_differentiation | 2.08007756 |
15 | MP0003300_gastrointestinal_ulcer | 2.07391015 |
16 | MP0003279_aneurysm | 2.07313644 |
17 | MP0003453_abnormal_keratinocyte_physiol | 2.00011892 |
18 | MP0005275_abnormal_skin_tensile | 1.99296085 |
19 | MP0010352_gastrointestinal_tract_polyps | 1.98527892 |
20 | MP0004859_abnormal_synaptic_plasticity | 1.98324167 |
21 | MP0005451_abnormal_body_composition | 1.93734557 |
22 | MP0000569_abnormal_digit_pigmentation | 1.91234713 |
23 | MP0004233_abnormal_muscle_weight | 1.89548526 |
24 | MP0004084_abnormal_cardiac_muscle | 1.84823031 |
25 | MP0001849_ear_inflammation | 1.81494660 |
26 | MP0004272_abnormal_basement_membrane | 1.80791764 |
27 | MP0003091_abnormal_cell_migration | 1.77464885 |
28 | MP0004087_abnormal_muscle_fiber | 1.63066909 |
29 | MP0001958_emphysema | 1.61978426 |
30 | MP0010030_abnormal_orbit_morphology | 1.60656676 |
31 | MP0003115_abnormal_respiratory_system | 1.59496520 |
32 | MP0000678_abnormal_parathyroid_gland | 1.54574882 |
33 | MP0002234_abnormal_pharynx_morphology | 1.49675696 |
34 | MP0005503_abnormal_tendon_morphology | 1.49556518 |
35 | MP0004510_myositis | 1.46255734 |
36 | MP0000534_abnormal_ureter_morphology | 1.44788245 |
37 | MP0010630_abnormal_cardiac_muscle | 1.44747488 |
38 | MP0008260_abnormal_autophagy | 1.44592952 |
39 | MP0000428_abnormal_craniofacial_morphol | 1.43520293 |
40 | MP0000750_abnormal_muscle_regeneration | 1.40400664 |
41 | MP0002653_abnormal_ependyma_morphology | 1.40187129 |
42 | MP0009780_abnormal_chondrocyte_physiolo | 1.39745073 |
43 | MP0004947_skin_inflammation | 1.36937159 |
44 | MP0002796_impaired_skin_barrier | 1.36197840 |
45 | MP0009840_abnormal_foam_cell | 1.35613147 |
46 | MP0002877_abnormal_melanocyte_morpholog | 1.35143530 |
47 | MP0000003_abnormal_adipose_tissue | 1.35134227 |
48 | MP0002998_abnormal_bone_remodeling | 1.32031437 |
49 | MP0002108_abnormal_muscle_morphology | 1.30562388 |
50 | MP0004185_abnormal_adipocyte_glucose | 1.29421892 |
51 | MP0002269_muscular_atrophy | 1.26938978 |
52 | MP0000759_abnormal_skeletal_muscle | 1.26859701 |
53 | MP0002089_abnormal_postnatal_growth/wei | 1.26381513 |
54 | MP0004145_abnormal_muscle_electrophysio | 1.23501422 |
55 | MP0001299_abnormal_eye_distance/ | 1.23430791 |
56 | MP0005023_abnormal_wound_healing | 1.22237486 |
57 | MP0005257_abnormal_intraocular_pressure | 1.18862192 |
58 | MP0001348_abnormal_lacrimal_gland | 1.16560588 |
59 | MP0002896_abnormal_bone_mineralization | 1.16114811 |
60 | MP0003385_abnormal_body_wall | 1.15015662 |
61 | MP0004197_abnormal_fetal_growth/weight/ | 1.14184388 |
62 | MP0003942_abnormal_urinary_system | 1.13101582 |
63 | MP0002909_abnormal_adrenal_gland | 1.12209729 |
64 | MP0003303_peritoneal_inflammation | 1.12195019 |
65 | MP0000537_abnormal_urethra_morphology | 1.11145046 |
66 | MP0000749_muscle_degeneration | 1.10680016 |
67 | MP0005508_abnormal_skeleton_morphology | 1.09385576 |
68 | * MP0002925_abnormal_cardiovascular_devel | 1.09165499 |
69 | MP0010234_abnormal_vibrissa_follicle | 1.08596329 |
70 | MP0000747_muscle_weakness | 1.07628401 |
71 | MP0002168_other_aberrant_phenotype | 1.07150977 |
72 | MP0003122_maternal_imprinting | 1.06546188 |
73 | MP0003436_decreased_susceptibility_to | 1.06434304 |
74 | MP0009384_cardiac_valve_regurgitation | 1.04699398 |
75 | MP0003329_amyloid_beta_deposits | 1.03168628 |
76 | MP0009053_abnormal_anal_canal | 1.00567682 |
77 | MP0000767_abnormal_smooth_muscle | 0.99441811 |
78 | MP0000858_altered_metastatic_potential | 0.99057208 |
79 | MP0006138_congestive_heart_failure | 0.98984405 |
80 | MP0002106_abnormal_muscle_physiology | 0.98963369 |
81 | MP0000467_abnormal_esophagus_morphology | 0.97867069 |
82 | MP0002249_abnormal_larynx_morphology | 0.97380363 |
83 | MP0005330_cardiomyopathy | 0.97169008 |
84 | * MP0000266_abnormal_heart_morphology | 0.96490425 |
85 | MP0003634_abnormal_glial_cell | 0.96128972 |
86 | * MP0003935_abnormal_craniofacial_develop | 0.95667350 |
87 | MP0004036_abnormal_muscle_relaxation | 0.95413858 |
88 | MP0005369_muscle_phenotype | 0.93746429 |
89 | MP0005501_abnormal_skin_physiology | 0.92775976 |
90 | MP0005595_abnormal_vascular_smooth | 0.92406814 |
91 | MP0002837_dystrophic_cardiac_calcinosis | 0.92052906 |
92 | MP0002060_abnormal_skin_morphology | 0.91924288 |
93 | MP0005248_abnormal_Harderian_gland | 0.91206219 |
94 | MP0004808_abnormal_hematopoietic_stem | 0.90867580 |
95 | MP0002932_abnormal_joint_morphology | 0.90257234 |
96 | * MP0005621_abnormal_cell_physiology | 0.89163714 |
97 | MP0000566_synostosis | 0.88600873 |
98 | MP0002084_abnormal_developmental_patter | 0.88181141 |
99 | MP0004130_abnormal_muscle_cell | 0.87388135 |
100 | MP0001915_intracranial_hemorrhage | 0.85629464 |
101 | MP0002116_abnormal_craniofacial_bone | 0.85096090 |
102 | MP0002128_abnormal_blood_circulation | 0.85004156 |
103 | MP0010368_abnormal_lymphatic_system | 0.84794097 |
104 | MP0005390_skeleton_phenotype | 0.84712244 |
105 | * MP0005375_adipose_tissue_phenotype | 0.84523554 |
106 | MP0002697_abnormal_eye_size | 0.83450910 |
107 | MP0003075_altered_response_to | 0.83336758 |
108 | MP0003172_abnormal_lysosome_physiology | 0.82108932 |
109 | MP0006054_spinal_hemorrhage | 0.81786431 |
110 | MP0004381_abnormal_hair_follicle | 0.81687288 |
111 | MP0002933_joint_inflammation | 0.78908532 |
112 | MP0003191_abnormal_cellular_cholesterol | 0.78078701 |
113 | MP0000013_abnormal_adipose_tissue | 0.78049663 |
114 | * MP0005666_abnormal_adipose_tissue | 0.76939168 |
115 | MP0003119_abnormal_digestive_system | 0.76450583 |
116 | MP0003828_pulmonary_edema | 0.76073293 |
117 | MP0001784_abnormal_fluid_regulation | 0.75794324 |
118 | MP0004264_abnormal_extraembryonic_tissu | 0.75556546 |
119 | MP0003879_abnormal_hair_cell | 0.75022992 |
120 | MP0002254_reproductive_system_inflammat | 0.74897794 |
121 | MP0009703_decreased_birth_body | 0.73952972 |
122 | MP0002092_abnormal_eye_morphology | 0.73780426 |
123 | MP0001614_abnormal_blood_vessel | 0.73766349 |
124 | MP0009931_abnormal_skin_appearance | 0.73071873 |
125 | MP0002085_abnormal_embryonic_tissue | 0.72768755 |
126 | MP0003984_embryonic_growth_retardation | 0.72378704 |
127 | MP0002088_abnormal_embryonic_growth/wei | 0.71563794 |
128 | MP0000432_abnormal_head_morphology | 0.71276430 |
129 | MP0009672_abnormal_birth_weight | 0.71225186 |
130 | MP0000579_abnormal_nail_morphology | 0.70445643 |
131 | MP0008770_decreased_survivor_rate | 0.70355529 |
132 | MP0000462_abnormal_digestive_system | 0.67525678 |
133 | MP0000762_abnormal_tongue_morphology | 0.67520678 |
134 | MP0002113_abnormal_skeleton_development | 0.67487984 |
135 | MP0003690_abnormal_glial_cell | 0.66550557 |
136 | MP0001216_abnormal_epidermal_layer | 0.65716195 |
137 | MP0005397_hematopoietic_system_phenotyp | 0.65226552 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Obstructive sleep apnea (HP:0002870) | 4.28895144 |
2 | Cerebral aneurysm (HP:0004944) | 4.15768973 |
3 | Protrusio acetabuli (HP:0003179) | 4.07203400 |
4 | Shallow orbits (HP:0000586) | 4.04749639 |
5 | Broad face (HP:0000283) | 3.78773534 |
6 | Hyperacusis (HP:0010780) | 3.50594225 |
7 | Ankle contracture (HP:0006466) | 3.36119020 |
8 | Premature rupture of membranes (HP:0001788) | 3.25681854 |
9 | Broad metatarsal (HP:0001783) | 3.10615600 |
10 | Bladder diverticulum (HP:0000015) | 3.06791524 |
11 | Increased connective tissue (HP:0009025) | 2.97094466 |
12 | Distal upper limb amyotrophy (HP:0007149) | 2.96639898 |
13 | Upper limb amyotrophy (HP:0009129) | 2.96639898 |
14 | Atrophic scars (HP:0001075) | 2.78848210 |
15 | Mitral valve prolapse (HP:0001634) | 2.77194641 |
16 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.76835539 |
17 | Short 4th metacarpal (HP:0010044) | 2.76835539 |
18 | Macroorchidism (HP:0000053) | 2.66149011 |
19 | Type 1 muscle fiber predominance (HP:0003803) | 2.64900462 |
20 | Hand muscle atrophy (HP:0009130) | 2.61539417 |
21 | Renal duplication (HP:0000075) | 2.59972635 |
22 | Bowel diverticulosis (HP:0005222) | 2.57742258 |
23 | Cervical subluxation (HP:0003308) | 2.56954534 |
24 | Aortic aneurysm (HP:0004942) | 2.51784111 |
25 | Genu recurvatum (HP:0002816) | 2.50893986 |
26 | Renovascular hypertension (HP:0100817) | 2.50578375 |
27 | Aneurysm (HP:0002617) | 2.48825539 |
28 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.48523248 |
29 | Neoplasm of the heart (HP:0100544) | 2.48070912 |
30 | Dilatation of the ascending aorta (HP:0005111) | 2.47136774 |
31 | Increased variability in muscle fiber diameter (HP:0003557) | 2.44135421 |
32 | Elfin facies (HP:0004428) | 2.43944444 |
33 | Abnormality of the lower motor neuron (HP:0002366) | 2.42534514 |
34 | Aortic dissection (HP:0002647) | 2.42497752 |
35 | Difficulty running (HP:0009046) | 2.41963263 |
36 | Fragile skin (HP:0001030) | 2.36677183 |
37 | Insomnia (HP:0100785) | 2.36224305 |
38 | Distal lower limb muscle weakness (HP:0009053) | 2.33024460 |
39 | Abnormality of the 4th metacarpal (HP:0010012) | 2.31877179 |
40 | Enlarged penis (HP:0000040) | 2.30221177 |
41 | Difficulty climbing stairs (HP:0003551) | 2.18439442 |
42 | Lymphangioma (HP:0100764) | 2.17507778 |
43 | Long palpebral fissure (HP:0000637) | 2.16878801 |
44 | Urethral obstruction (HP:0000796) | 2.15771870 |
45 | Hyporeflexia of lower limbs (HP:0002600) | 2.15206352 |
46 | Flat cornea (HP:0007720) | 2.14630110 |
47 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.11883809 |
48 | Pointed chin (HP:0000307) | 2.11418460 |
49 | Overriding aorta (HP:0002623) | 2.10185854 |
50 | Turricephaly (HP:0000262) | 2.09353083 |
51 | Stridor (HP:0010307) | 2.08293608 |
52 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.07489154 |
53 | Deviation of the hallux (HP:0010051) | 2.07393864 |
54 | Flat acetabular roof (HP:0003180) | 2.07373547 |
55 | Vertebral compression fractures (HP:0002953) | 2.06984542 |
56 | Wormian bones (HP:0002645) | 2.05794390 |
57 | Peritonitis (HP:0002586) | 2.04614564 |
58 | Nuclear cataract (HP:0100018) | 2.02993932 |
59 | Striae distensae (HP:0001065) | 2.02941138 |
60 | Hallux valgus (HP:0001822) | 2.01994847 |
61 | Advanced eruption of teeth (HP:0006288) | 2.01579868 |
62 | Milia (HP:0001056) | 2.00938696 |
63 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.00057367 |
64 | Biconcave vertebral bodies (HP:0004586) | 1.98873343 |
65 | Disproportionate tall stature (HP:0001519) | 1.97915089 |
66 | J-shaped sella turcica (HP:0002680) | 1.97425739 |
67 | Narrow palate (HP:0000189) | 1.97364127 |
68 | Spinal rigidity (HP:0003306) | 1.92355268 |
69 | Spondylolisthesis (HP:0003302) | 1.89422493 |
70 | Trigonocephaly (HP:0000243) | 1.87718630 |
71 | Achilles tendon contracture (HP:0001771) | 1.86350928 |
72 | Blue sclerae (HP:0000592) | 1.86317234 |
73 | Ankyloglossia (HP:0010296) | 1.86280521 |
74 | Scapular winging (HP:0003691) | 1.85932243 |
75 | Premature skin wrinkling (HP:0100678) | 1.85464779 |
76 | Natal tooth (HP:0000695) | 1.85442273 |
77 | Hypoventilation (HP:0002791) | 1.85316691 |
78 | Slender build (HP:0001533) | 1.83976046 |
79 | Axonal loss (HP:0003447) | 1.83201452 |
80 | Cerebral inclusion bodies (HP:0100314) | 1.82863967 |
81 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.82634987 |
82 | Broad thumb (HP:0011304) | 1.80676097 |
83 | Hemorrhage of the eye (HP:0011885) | 1.79332743 |
84 | Dislocated radial head (HP:0003083) | 1.78770950 |
85 | Long eyelashes (HP:0000527) | 1.78607800 |
86 | Neurofibrillary tangles (HP:0002185) | 1.78430351 |
87 | Thin ribs (HP:0000883) | 1.78421917 |
88 | Arnold-Chiari malformation (HP:0002308) | 1.78114028 |
89 | Abnormality of the thoracic spine (HP:0100711) | 1.77745019 |
90 | Lower limb amyotrophy (HP:0007210) | 1.76600153 |
91 | Distal lower limb amyotrophy (HP:0008944) | 1.75214790 |
92 | Persistence of primary teeth (HP:0006335) | 1.74825379 |
93 | Bronchomalacia (HP:0002780) | 1.74815995 |
94 | Thin bony cortex (HP:0002753) | 1.74414807 |
95 | Hypoplastic ischia (HP:0003175) | 1.74314046 |
96 | Wrist flexion contracture (HP:0001239) | 1.73755950 |
97 | Short nail (HP:0001799) | 1.73479823 |
98 | Asymmetry of the thorax (HP:0001555) | 1.73405828 |
99 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.73307324 |
100 | Osteolytic defects of the hand bones (HP:0009699) | 1.73307324 |
101 | Joint laxity (HP:0001388) | 1.73068138 |
102 | Abnormality of the fingertips (HP:0001211) | 1.72823992 |
103 | Rectal prolapse (HP:0002035) | 1.72483834 |
104 | Patellar dislocation (HP:0002999) | 1.71448507 |
105 | Ulnar bowing (HP:0003031) | 1.71371640 |
106 | Hypercortisolism (HP:0001578) | 1.70717451 |
107 | Dysmetric saccades (HP:0000641) | 1.70108963 |
108 | Precocious puberty (HP:0000826) | 1.70079557 |
109 | Aortic regurgitation (HP:0001659) | 1.70032303 |
110 | Hyperextensible skin (HP:0000974) | 1.69476526 |
111 | Astrocytoma (HP:0009592) | 1.68118795 |
112 | Abnormality of the astrocytes (HP:0100707) | 1.68118795 |
113 | Abnormality of the radial head (HP:0003995) | 1.67760583 |
114 | Vertebral arch anomaly (HP:0008438) | 1.66791386 |
115 | Easy fatigability (HP:0003388) | 1.66769990 |
116 | Arterial tortuosity (HP:0005116) | 1.65908323 |
117 | Abnormality of oral frenula (HP:0000190) | 1.65880909 |
118 | Increased nuchal translucency (HP:0010880) | 1.65124237 |
119 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.64564069 |
120 | Interstitial pulmonary disease (HP:0006530) | 1.64415061 |
121 | Abnormality of the Achilles tendon (HP:0005109) | 1.62737883 |
122 | Genetic anticipation (HP:0003743) | 1.61979715 |
123 | Buphthalmos (HP:0000557) | 1.61720257 |
124 | Sudden death (HP:0001699) | 1.60526470 |
125 | Long toe (HP:0010511) | 1.60405298 |
126 | Selective tooth agenesis (HP:0001592) | 1.59814336 |
127 | Increased density of long bones (HP:0006392) | 1.59400439 |
128 | Right ventricular cardiomyopathy (HP:0011663) | 1.59225391 |
129 | Annular pancreas (HP:0001734) | 1.59211331 |
130 | Vascular tortuosity (HP:0004948) | 1.58998506 |
131 | Neonatal short-limb short stature (HP:0008921) | 1.58734170 |
132 | Emphysema (HP:0002097) | 1.58051781 |
133 | Dysostosis multiplex (HP:0000943) | 1.57595858 |
134 | Muscle fiber splitting (HP:0003555) | 1.56809446 |
135 | Obsessive-compulsive behavior (HP:0000722) | 1.56674009 |
136 | Generalized amyotrophy (HP:0003700) | 1.55743904 |
137 | Fibroma (HP:0010614) | 1.55517783 |
138 | Mitral regurgitation (HP:0001653) | 1.55210864 |
139 | Venous abnormality (HP:0002624) | 1.54936309 |
140 | Round ear (HP:0100830) | 1.54053889 |
141 | Overgrowth (HP:0001548) | 1.52584881 |
142 | Bundle branch block (HP:0011710) | 1.51503756 |
143 | Follicular hyperkeratosis (HP:0007502) | 1.51449768 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 4.41227031 |
2 | CDK12 | 3.70371086 |
3 | PKN2 | 2.98976630 |
4 | PRPF4B | 2.83828162 |
5 | MAP3K10 | 2.72992865 |
6 | RIPK1 | 2.70292003 |
7 | SMG1 | 2.69919483 |
8 | EEF2K | 2.60448722 |
9 | TTN | 2.53439026 |
10 | IRAK3 | 2.53435317 |
11 | ICK | 2.49697320 |
12 | SIK1 | 2.47349053 |
13 | ERN1 | 2.44602125 |
14 | EPHA2 | 2.29280380 |
15 | PDGFRA | 2.26346890 |
16 | MST1R | 1.96091578 |
17 | PRKD3 | 1.94807791 |
18 | CAMK1G | 1.91553709 |
19 | TYRO3 | 1.82099747 |
20 | PTK6 | 1.79417979 |
21 | DMPK | 1.75668005 |
22 | CAMK1D | 1.68858588 |
23 | DDR2 | 1.68101517 |
24 | BMX | 1.62041030 |
25 | MTOR | 1.56244929 |
26 | SIK2 | 1.51421354 |
27 | NTRK1 | 1.49914501 |
28 | LATS1 | 1.42191552 |
29 | EPHB1 | 1.40272490 |
30 | TAOK1 | 1.37777722 |
31 | PTK2 | 1.37541660 |
32 | BRD4 | 1.33352396 |
33 | PAK6 | 1.32732160 |
34 | LATS2 | 1.31796340 |
35 | ALK | 1.24697101 |
36 | MAP3K7 | 1.21293069 |
37 | EPHB2 | 1.17590113 |
38 | PAK2 | 1.14456762 |
39 | MAP3K13 | 1.12918210 |
40 | CDC42BPA | 1.11197208 |
41 | PAK4 | 1.09120224 |
42 | MAP3K9 | 1.05414364 |
43 | PDGFRB | 1.01708633 |
44 | PRKCH | 1.01398411 |
45 | RET | 0.99144726 |
46 | TESK1 | 0.94906361 |
47 | MET | 0.94554428 |
48 | KSR2 | 0.92938501 |
49 | MARK2 | 0.92925199 |
50 | TNK2 | 0.91567638 |
51 | STK38 | 0.88217364 |
52 | IRAK2 | 0.88130136 |
53 | NTRK2 | 0.87666318 |
54 | CAMKK1 | 0.87602622 |
55 | TAOK2 | 0.85388358 |
56 | KSR1 | 0.84187244 |
57 | MAP2K3 | 0.83719387 |
58 | LMTK2 | 0.83419479 |
59 | FGFR1 | 0.83250492 |
60 | PRKD2 | 0.81502615 |
61 | MAP3K3 | 0.81192879 |
62 | RPS6KL1 | 0.80002237 |
63 | RPS6KC1 | 0.80002237 |
64 | NME2 | 0.79432717 |
65 | DAPK2 | 0.77252593 |
66 | WNK1 | 0.76834802 |
67 | TGFBR2 | 0.76536019 |
68 | LRRK2 | 0.76379165 |
69 | FER | 0.76273904 |
70 | ERBB2 | 0.75795650 |
71 | PAK3 | 0.73915485 |
72 | FGFR4 | 0.72979053 |
73 | PDPK1 | 0.72315718 |
74 | MAP3K6 | 0.70778596 |
75 | CAMK4 | 0.67669665 |
76 | NTRK3 | 0.67663004 |
77 | MAPK7 | 0.66870974 |
78 | MAP3K11 | 0.66542047 |
79 | DYRK1B | 0.66076676 |
80 | PRKD1 | 0.64591939 |
81 | CDK6 | 0.63455244 |
82 | PTK2B | 0.62836096 |
83 | MAP3K2 | 0.61281477 |
84 | FGFR3 | 0.60417967 |
85 | RPS6KA6 | 0.58546958 |
86 | MAPK12 | 0.58342234 |
87 | SGK3 | 0.57396262 |
88 | MAPK11 | 0.56842225 |
89 | SCYL2 | 0.56820564 |
90 | ARAF | 0.56178308 |
91 | HIPK2 | 0.56098153 |
92 | STK11 | 0.54445588 |
93 | SIK3 | 0.53544931 |
94 | PHKG1 | 0.53249981 |
95 | PHKG2 | 0.53249981 |
96 | RIPK4 | 0.52867682 |
97 | ROCK1 | 0.52664662 |
98 | MAP4K1 | 0.51444805 |
99 | TBK1 | 0.51278275 |
100 | NEK1 | 0.50806972 |
101 | MAP3K1 | 0.49841260 |
102 | MOS | 0.49672263 |
103 | ZAP70 | 0.47202488 |
104 | TRPM7 | 0.47189157 |
105 | PRKG2 | 0.46873732 |
106 | RPS6KA2 | 0.46816432 |
107 | FGFR2 | 0.45493236 |
108 | JAK1 | 0.45373063 |
109 | MAP2K2 | 0.44078637 |
110 | UHMK1 | 0.42335705 |
111 | MAP3K14 | 0.41787270 |
112 | MAPK8 | 0.41749266 |
113 | SRC | 0.41523297 |
114 | IRAK4 | 0.41424005 |
115 | CDK9 | 0.39709463 |
116 | ROCK2 | 0.38940496 |
117 | HCK | 0.38388046 |
118 | ILK | 0.37722909 |
119 | MINK1 | 0.36879776 |
120 | RPS6KA1 | 0.36638096 |
121 | CDK4 | 0.34993937 |
122 | MAPKAPK2 | 0.34170161 |
123 | MAP3K8 | 0.34006660 |
124 | * MAPK1 | 0.33893211 |
125 | STK10 | 0.33146572 |
126 | PDK1 | 0.32605669 |
127 | MAPK10 | 0.32507775 |
128 | RPS6KA3 | 0.32186610 |
129 | CAMK1 | 0.31928091 |
130 | MAP3K4 | 0.31868289 |
131 | BLK | 0.30323682 |
132 | MATK | 0.30251078 |
133 | STK3 | 0.29965324 |
134 | CSF1R | 0.29599404 |
135 | MELK | 0.29479887 |
136 | MAPK4 | 0.29448780 |
137 | FYN | 0.28604134 |
138 | CDK5 | 0.28498173 |
139 | EPHA3 | 0.28276124 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Other glycan degradation_Homo sapiens_hsa00511 | 1.96883677 |
2 | Focal adhesion_Homo sapiens_hsa04510 | 1.69276226 |
3 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.66727162 |
4 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.64543322 |
5 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.61399087 |
6 | Lysine degradation_Homo sapiens_hsa00310 | 1.58134836 |
7 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.53196300 |
8 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.52550417 |
9 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.49404494 |
10 | Adherens junction_Homo sapiens_hsa04520 | 1.49167253 |
11 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.48308963 |
12 | Glioma_Homo sapiens_hsa05214 | 1.47085666 |
13 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.45560452 |
14 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.45051152 |
15 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.42010135 |
16 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.40751681 |
17 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.39260237 |
18 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.36699292 |
19 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.35805759 |
20 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.31402318 |
21 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.31364378 |
22 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.31076875 |
23 | Prion diseases_Homo sapiens_hsa05020 | 1.30370284 |
24 | * Notch signaling pathway_Homo sapiens_hsa04330 | 1.29837641 |
25 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.28732115 |
26 | Amoebiasis_Homo sapiens_hsa05146 | 1.28077614 |
27 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.27533477 |
28 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.27031909 |
29 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.23229574 |
30 | Endometrial cancer_Homo sapiens_hsa05213 | 1.23226983 |
31 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.17975528 |
32 | Bladder cancer_Homo sapiens_hsa05219 | 1.17344623 |
33 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.16456835 |
34 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.15927282 |
35 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.15775727 |
36 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.15498886 |
37 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.14589120 |
38 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.14152175 |
39 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.13470269 |
40 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.11737488 |
41 | Insulin resistance_Homo sapiens_hsa04931 | 1.10007843 |
42 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.07277843 |
43 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.06806190 |
44 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.06590086 |
45 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.05334815 |
46 | Axon guidance_Homo sapiens_hsa04360 | 1.05289580 |
47 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.05153821 |
48 | Viral myocarditis_Homo sapiens_hsa05416 | 1.04948352 |
49 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.03677810 |
50 | Colorectal cancer_Homo sapiens_hsa05210 | 1.02842295 |
51 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.01378169 |
52 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.00328988 |
53 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.00263175 |
54 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.00152659 |
55 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.00072420 |
56 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.99960886 |
57 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.99252611 |
58 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.97337024 |
59 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.97173892 |
60 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.96431052 |
61 | Melanogenesis_Homo sapiens_hsa04916 | 0.94688250 |
62 | Insulin secretion_Homo sapiens_hsa04911 | 0.94005149 |
63 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.93581088 |
64 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.93171187 |
65 | Circadian entrainment_Homo sapiens_hsa04713 | 0.93119996 |
66 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.92761427 |
67 | Gap junction_Homo sapiens_hsa04540 | 0.89828620 |
68 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.89387462 |
69 | Long-term potentiation_Homo sapiens_hsa04720 | 0.88246791 |
70 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.88233657 |
71 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.87648126 |
72 | Platelet activation_Homo sapiens_hsa04611 | 0.86779102 |
73 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.85212680 |
74 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.85178810 |
75 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.84923163 |
76 | Salivary secretion_Homo sapiens_hsa04970 | 0.82824248 |
77 | Hepatitis B_Homo sapiens_hsa05161 | 0.82199028 |
78 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.82123363 |
79 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.81140306 |
80 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.81006836 |
81 | Hepatitis C_Homo sapiens_hsa05160 | 0.80735847 |
82 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.79976641 |
83 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.79684446 |
84 | Tight junction_Homo sapiens_hsa04530 | 0.79473597 |
85 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.79259058 |
86 | Renin secretion_Homo sapiens_hsa04924 | 0.79046909 |
87 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.78845365 |
88 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.78790386 |
89 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.78734961 |
90 | Pathways in cancer_Homo sapiens_hsa05200 | 0.78481870 |
91 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.77763323 |
92 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.77117360 |
93 | Lysosome_Homo sapiens_hsa04142 | 0.75718685 |
94 | Endocytosis_Homo sapiens_hsa04144 | 0.75352423 |
95 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.75172757 |
96 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.74468460 |
97 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.74208470 |
98 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.73797649 |
99 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.72054906 |
100 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.70609026 |
101 | Prostate cancer_Homo sapiens_hsa05215 | 0.70308574 |
102 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.70065775 |
103 | HTLV-I infection_Homo sapiens_hsa05166 | 0.69635367 |
104 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.69545412 |
105 | Cocaine addiction_Homo sapiens_hsa05030 | 0.68431930 |
106 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.67100550 |
107 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.67015763 |
108 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.66913397 |
109 | Influenza A_Homo sapiens_hsa05164 | 0.66434377 |
110 | Salmonella infection_Homo sapiens_hsa05132 | 0.65824109 |
111 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.65077248 |
112 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.64730283 |
113 | Apoptosis_Homo sapiens_hsa04210 | 0.64586799 |
114 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.63735139 |
115 | Thyroid cancer_Homo sapiens_hsa05216 | 0.63116414 |
116 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.62342536 |
117 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.61580830 |
118 | Galactose metabolism_Homo sapiens_hsa00052 | 0.60147818 |
119 | Olfactory transduction_Homo sapiens_hsa04740 | 0.59960620 |
120 | Leishmaniasis_Homo sapiens_hsa05140 | 0.59592823 |
121 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.59320392 |
122 | Malaria_Homo sapiens_hsa05144 | 0.57750195 |