Rank | Gene Set | Z-score |
---|---|---|
1 | neuron cell-cell adhesion (GO:0007158) | 5.30513598 |
2 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.92916639 |
3 | response to pheromone (GO:0019236) | 4.89171176 |
4 | synaptic vesicle exocytosis (GO:0016079) | 4.83147632 |
5 | vocalization behavior (GO:0071625) | 4.64200182 |
6 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.62344553 |
7 | protein localization to synapse (GO:0035418) | 4.52135313 |
8 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.51481976 |
9 | establishment of mitochondrion localization (GO:0051654) | 4.36103199 |
10 | * neuron recognition (GO:0008038) | 4.26264842 |
11 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.22411882 |
12 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.22079504 |
13 | synaptic vesicle maturation (GO:0016188) | 4.12247869 |
14 | locomotory exploration behavior (GO:0035641) | 4.03059759 |
15 | behavioral response to nicotine (GO:0035095) | 4.02019287 |
16 | layer formation in cerebral cortex (GO:0021819) | 4.01336744 |
17 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.95281326 |
18 | glutamate secretion (GO:0014047) | 3.92489087 |
19 | positive regulation of synapse assembly (GO:0051965) | 3.88390006 |
20 | neurotransmitter secretion (GO:0007269) | 3.87913188 |
21 | exploration behavior (GO:0035640) | 3.87399592 |
22 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.86170948 |
23 | regulation of glutamate secretion (GO:0014048) | 3.83136992 |
24 | dendritic spine morphogenesis (GO:0060997) | 3.83065005 |
25 | negative regulation of microtubule polymerization (GO:0031115) | 3.77906274 |
26 | regulation of synaptic vesicle transport (GO:1902803) | 3.76599935 |
27 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.70385830 |
28 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.69103986 |
29 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.64137699 |
30 | mitochondrion transport along microtubule (GO:0047497) | 3.63931043 |
31 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.63931043 |
32 | glutamate receptor signaling pathway (GO:0007215) | 3.61592166 |
33 | proline transport (GO:0015824) | 3.54920784 |
34 | transmission of nerve impulse (GO:0019226) | 3.47983289 |
35 | neuronal action potential propagation (GO:0019227) | 3.46999276 |
36 | * axonal fasciculation (GO:0007413) | 3.45650056 |
37 | neuromuscular process controlling posture (GO:0050884) | 3.45636195 |
38 | mating behavior (GO:0007617) | 3.45396231 |
39 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.44887728 |
40 | neurofilament cytoskeleton organization (GO:0060052) | 3.40760936 |
41 | cell migration in hindbrain (GO:0021535) | 3.36977378 |
42 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.36490072 |
43 | neurotransmitter transport (GO:0006836) | 3.35395419 |
44 | retinal ganglion cell axon guidance (GO:0031290) | 3.35099478 |
45 | nucleobase catabolic process (GO:0046113) | 3.31103342 |
46 | synaptic transmission, glutamatergic (GO:0035249) | 3.29781400 |
47 | regulation of synapse structural plasticity (GO:0051823) | 3.29548179 |
48 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.29297627 |
49 | nonmotile primary cilium assembly (GO:0035058) | 3.28094182 |
50 | axon extension involved in axon guidance (GO:0048846) | 3.27512644 |
51 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.27512644 |
52 | activation of protein kinase A activity (GO:0034199) | 3.26936217 |
53 | neuron-neuron synaptic transmission (GO:0007270) | 3.25819611 |
54 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.24119189 |
55 | postsynaptic membrane organization (GO:0001941) | 3.23902640 |
56 | dendrite morphogenesis (GO:0048813) | 3.22176994 |
57 | regulation of vesicle fusion (GO:0031338) | 3.20539213 |
58 | synaptic vesicle endocytosis (GO:0048488) | 3.17710264 |
59 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.17609658 |
60 | regulation of synapse assembly (GO:0051963) | 3.17493966 |
61 | positive regulation of gastrulation (GO:2000543) | 3.15301235 |
62 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.13985540 |
63 | auditory behavior (GO:0031223) | 3.11401393 |
64 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.10532665 |
65 | synapse assembly (GO:0007416) | 3.09623205 |
66 | * axon extension (GO:0048675) | 3.08754164 |
67 | regulation of neurotransmitter levels (GO:0001505) | 3.07118148 |
68 | negative regulation of amino acid transport (GO:0051956) | 3.02637833 |
69 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.02598013 |
70 | positive regulation of amino acid transport (GO:0051957) | 3.02473325 |
71 | response to histamine (GO:0034776) | 3.02348371 |
72 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.99195117 |
73 | presynaptic membrane assembly (GO:0097105) | 2.98881627 |
74 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.96723398 |
75 | adult feeding behavior (GO:0008343) | 2.96182989 |
76 | short-term memory (GO:0007614) | 2.94271504 |
77 | dendrite development (GO:0016358) | 2.91587531 |
78 | opioid receptor signaling pathway (GO:0038003) | 2.91164479 |
79 | long-term memory (GO:0007616) | 2.90479206 |
80 | intraspecies interaction between organisms (GO:0051703) | 2.89096999 |
81 | social behavior (GO:0035176) | 2.89096999 |
82 | regulation of respiratory system process (GO:0044065) | 2.88288115 |
83 | presynaptic membrane organization (GO:0097090) | 2.88134077 |
84 | regulation of postsynaptic membrane potential (GO:0060078) | 2.86551027 |
85 | cerebellar Purkinje cell layer development (GO:0021680) | 2.86154856 |
86 | regulation of synaptic transmission, GABAergic (GO:0032228) | 2.85489815 |
87 | membrane hyperpolarization (GO:0060081) | 2.84475973 |
88 | neuron fate determination (GO:0048664) | 2.83807483 |
89 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.83786224 |
90 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.83330765 |
91 | synaptic vesicle transport (GO:0048489) | 2.83267857 |
92 | establishment of synaptic vesicle localization (GO:0097480) | 2.83267857 |
93 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.83265781 |
94 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.83203385 |
95 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 2.82604343 |
96 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.82036103 |
97 | synapse organization (GO:0050808) | 2.80765324 |
98 | chaperone-mediated protein transport (GO:0072321) | 2.80297759 |
99 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.80210440 |
100 | gamma-aminobutyric acid transport (GO:0015812) | 2.79906046 |
101 | regulation of synapse organization (GO:0050807) | 2.79755829 |
102 | response to auditory stimulus (GO:0010996) | 2.79583924 |
103 | neuronal ion channel clustering (GO:0045161) | 2.79133781 |
104 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 2.79020978 |
105 | spinal cord development (GO:0021510) | 2.78375567 |
106 | dopamine receptor signaling pathway (GO:0007212) | 2.77844669 |
107 | prepulse inhibition (GO:0060134) | 2.77806690 |
108 | behavioral defense response (GO:0002209) | 2.77583433 |
109 | behavioral fear response (GO:0001662) | 2.77583433 |
110 | somite development (GO:0061053) | 2.76572050 |
111 | regulation of neurotransmitter secretion (GO:0046928) | 2.76514091 |
112 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.75527550 |
113 | spinal cord association neuron differentiation (GO:0021527) | 2.74727099 |
114 | ATP synthesis coupled proton transport (GO:0015986) | 2.74426648 |
115 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.74426648 |
116 | positive regulation of membrane potential (GO:0045838) | 2.73299567 |
117 | positive regulation of synapse maturation (GO:0090129) | 2.72623040 |
118 | fear response (GO:0042596) | 2.71866989 |
119 | substrate-independent telencephalic tangential migration (GO:0021826) | 2.71657521 |
120 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 2.71657521 |
121 | regulation of protein kinase A signaling (GO:0010738) | 2.71310905 |
122 | establishment of vesicle localization (GO:0051650) | 2.71142007 |
123 | hippocampus development (GO:0021766) | 2.71002310 |
124 | negative regulation of axon guidance (GO:1902668) | 2.70818668 |
125 | sequestering of actin monomers (GO:0042989) | 2.69854093 |
126 | negative regulation of axonogenesis (GO:0050771) | 2.69799343 |
127 | mechanosensory behavior (GO:0007638) | 2.69710410 |
128 | glycosphingolipid biosynthetic process (GO:0006688) | 2.68433658 |
129 | startle response (GO:0001964) | 2.66539287 |
130 | negative regulation of axon extension (GO:0030517) | 2.65412591 |
131 | neurotransmitter-gated ion channel clustering (GO:0072578) | 2.63458956 |
132 | head development (GO:0060322) | 2.61973816 |
133 | regulation of axon guidance (GO:1902667) | 2.54065100 |
134 | epithelial cell differentiation involved in kidney development (GO:0035850) | 2.54015232 |
135 | adult walking behavior (GO:0007628) | 2.51386497 |
136 | synaptic transmission, cholinergic (GO:0007271) | 2.49089511 |
137 | cell proliferation in forebrain (GO:0021846) | 2.47442358 |
138 | * neuron projection extension (GO:1990138) | 2.46146920 |
139 | neuromuscular synaptic transmission (GO:0007274) | 2.46066688 |
140 | protein localization to cilium (GO:0061512) | 2.38480067 |
141 | membrane depolarization during action potential (GO:0086010) | 2.38341449 |
142 | response to dietary excess (GO:0002021) | 2.38340755 |
143 | establishment of nucleus localization (GO:0040023) | 2.38326190 |
144 | limb bud formation (GO:0060174) | 2.34372995 |
145 | forebrain neuron differentiation (GO:0021879) | 2.33807153 |
146 | * neuron migration (GO:0001764) | 2.32526310 |
147 | axon cargo transport (GO:0008088) | 2.31730728 |
148 | protein polyglutamylation (GO:0018095) | 2.30806730 |
149 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 2.30272754 |
150 | otic vesicle formation (GO:0030916) | 2.29647402 |
151 | axon ensheathment in central nervous system (GO:0032291) | 2.28254121 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.72877249 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.29940495 |
3 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.11536077 |
4 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.11508676 |
5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.09233846 |
6 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.00221825 |
7 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.89836786 |
8 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.77341868 |
9 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.76713803 |
10 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.76006903 |
11 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.70042280 |
12 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.68033425 |
13 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.62991339 |
14 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.62991339 |
15 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.60101559 |
16 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.54246159 |
17 | * SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.53648391 |
18 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.46742853 |
19 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.40313546 |
20 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.40146125 |
21 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.39581443 |
22 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.38835452 |
23 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.23805975 |
24 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.18870077 |
25 | * BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.16073811 |
26 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.14542958 |
27 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.13596709 |
28 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.08650086 |
29 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.02726467 |
30 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.97918344 |
31 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.97517274 |
32 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.90959635 |
33 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.90507827 |
34 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.86684924 |
35 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.83450922 |
36 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.79507686 |
37 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.78838576 |
38 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.75945964 |
39 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.69838740 |
40 | * RNF2_27304074_Chip-Seq_NSC_Mouse | 1.66360886 |
41 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.55680875 |
42 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.55534938 |
43 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.55422912 |
44 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.55032716 |
45 | P300_19829295_ChIP-Seq_ESCs_Human | 1.54374188 |
46 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.50570584 |
47 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.42713858 |
48 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.39750739 |
49 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.39408493 |
50 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.33432919 |
51 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.33158030 |
52 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.28299179 |
53 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.27362298 |
54 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.25029829 |
55 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.23832034 |
56 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.22806796 |
57 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.22278947 |
58 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.21760971 |
59 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.21572265 |
60 | VDR_22108803_ChIP-Seq_LS180_Human | 1.20737527 |
61 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.20670761 |
62 | AR_25329375_ChIP-Seq_VCAP_Human | 1.20394487 |
63 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.18433273 |
64 | FUS_26573619_Chip-Seq_HEK293_Human | 1.17933122 |
65 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.16638229 |
66 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.16591925 |
67 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.15700129 |
68 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.12495314 |
69 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.09505006 |
70 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.09316048 |
71 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.09046571 |
72 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.09037300 |
73 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.08525056 |
74 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.05228491 |
75 | JUN_21703547_ChIP-Seq_K562_Human | 1.03817792 |
76 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.03705250 |
77 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.03535844 |
78 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.02555268 |
79 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.01907859 |
80 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.01578922 |
81 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.01303683 |
82 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.00567320 |
83 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.00248567 |
84 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.99641441 |
85 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.99057680 |
86 | AR_19668381_ChIP-Seq_PC3_Human | 0.98676111 |
87 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.98430328 |
88 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.96708001 |
89 | STAT3_23295773_ChIP-Seq_U87_Human | 0.95750715 |
90 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95637501 |
91 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.95556433 |
92 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.94686765 |
93 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.94061956 |
94 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.93854366 |
95 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.93854366 |
96 | * CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.93260864 |
97 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.91903563 |
98 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 0.91526030 |
99 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.90232803 |
100 | * SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.90166157 |
101 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.89332172 |
102 | EWS_26573619_Chip-Seq_HEK293_Human | 0.89161511 |
103 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.88957975 |
104 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.88847992 |
105 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.88014836 |
106 | * TCF4_23295773_ChIP-Seq_U87_Human | 0.86314302 |
107 | * YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.85117831 |
108 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.85027382 |
109 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.84691662 |
110 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 0.84376727 |
111 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.83843574 |
112 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.83314799 |
113 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.82802538 |
114 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.82694024 |
115 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.82694024 |
116 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.82139559 |
117 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.80925512 |
118 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.80910522 |
119 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 0.80512631 |
120 | KDM2B_26808549_Chip-Seq_REH_Human | 0.80140678 |
121 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.78236133 |
122 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.78114121 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 5.07642138 |
2 | MP0004859_abnormal_synaptic_plasticity | 4.20280692 |
3 | MP0003635_abnormal_synaptic_transmissio | 3.44007811 |
4 | MP0005423_abnormal_somatic_nervous | 3.32570997 |
5 | * MP0006276_abnormal_autonomic_nervous | 3.26526506 |
6 | MP0005645_abnormal_hypothalamus_physiol | 3.21045093 |
7 | MP0001968_abnormal_touch/_nociception | 3.16255673 |
8 | * MP0003122_maternal_imprinting | 3.13229059 |
9 | MP0009745_abnormal_behavioral_response | 2.86877865 |
10 | MP0004270_analgesia | 2.85148457 |
11 | * MP0002063_abnormal_learning/memory/cond | 2.82075973 |
12 | MP0002064_seizures | 2.70061569 |
13 | MP0002572_abnormal_emotion/affect_behav | 2.57079894 |
14 | MP0009046_muscle_twitch | 2.50280971 |
15 | MP0002734_abnormal_mechanical_nocicepti | 2.48108853 |
16 | MP0001529_abnormal_vocalization | 2.48006206 |
17 | MP0002736_abnormal_nociception_after | 2.38250532 |
18 | MP0000778_abnormal_nervous_system | 2.37816367 |
19 | MP0002735_abnormal_chemical_nociception | 2.32001373 |
20 | * MP0002272_abnormal_nervous_system | 2.14795838 |
21 | MP0002653_abnormal_ependyma_morphology | 2.13624358 |
22 | MP0001486_abnormal_startle_reflex | 2.08044099 |
23 | * MP0001440_abnormal_grooming_behavior | 2.06520685 |
24 | * MP0002733_abnormal_thermal_nociception | 2.05051094 |
25 | MP0001501_abnormal_sleep_pattern | 2.03415283 |
26 | MP0002067_abnormal_sensory_capabilities | 1.95205911 |
27 | * MP0002184_abnormal_innervation | 1.94250568 |
28 | MP0002557_abnormal_social/conspecific_i | 1.94248788 |
29 | MP0001984_abnormal_olfaction | 1.92829896 |
30 | * MP0001970_abnormal_pain_threshold | 1.88488507 |
31 | MP0006292_abnormal_olfactory_placode | 1.83280941 |
32 | MP0003123_paternal_imprinting | 1.82190799 |
33 | MP0001905_abnormal_dopamine_level | 1.80670166 |
34 | MP0005386_behavior/neurological_phenoty | 1.80183195 |
35 | MP0004924_abnormal_behavior | 1.80183195 |
36 | MP0001502_abnormal_circadian_rhythm | 1.65609728 |
37 | MP0000566_synostosis | 1.65493577 |
38 | MP0003329_amyloid_beta_deposits | 1.62316972 |
39 | MP0000751_myopathy | 1.60038254 |
40 | MP0000049_abnormal_middle_ear | 1.51584057 |
41 | MP0002822_catalepsy | 1.50683478 |
42 | MP0003136_yellow_coat_color | 1.50232214 |
43 | MP0004811_abnormal_neuron_physiology | 1.50057355 |
44 | MP0000955_abnormal_spinal_cord | 1.49709387 |
45 | * MP0003121_genomic_imprinting | 1.49685155 |
46 | MP0005646_abnormal_pituitary_gland | 1.49662454 |
47 | MP0008789_abnormal_olfactory_epithelium | 1.49548838 |
48 | MP0002909_abnormal_adrenal_gland | 1.47570833 |
49 | MP0003787_abnormal_imprinting | 1.45524460 |
50 | * MP0002882_abnormal_neuron_morphology | 1.41646395 |
51 | MP0003890_abnormal_embryonic-extraembry | 1.39517350 |
52 | MP0008877_abnormal_DNA_methylation | 1.37131686 |
53 | MP0002638_abnormal_pupillary_reflex | 1.34701259 |
54 | MP0000631_abnormal_neuroendocrine_gland | 1.34352077 |
55 | MP0004858_abnormal_nervous_system | 1.33450072 |
56 | * MP0002066_abnormal_motor_capabilities/c | 1.31580951 |
57 | MP0002938_white_spotting | 1.30166554 |
58 | MP0003011_delayed_dark_adaptation | 1.30047526 |
59 | MP0003942_abnormal_urinary_system | 1.28949038 |
60 | MP0001188_hyperpigmentation | 1.26817997 |
61 | MP0002837_dystrophic_cardiac_calcinosis | 1.26022923 |
62 | MP0010386_abnormal_urinary_bladder | 1.23828072 |
63 | MP0006072_abnormal_retinal_apoptosis | 1.17590958 |
64 | MP0008569_lethality_at_weaning | 1.16382460 |
65 | * MP0004142_abnormal_muscle_tone | 1.15892231 |
66 | * MP0002152_abnormal_brain_morphology | 1.15813245 |
67 | MP0010030_abnormal_orbit_morphology | 1.11691167 |
68 | MP0004742_abnormal_vestibular_system | 1.09674219 |
69 | MP0000534_abnormal_ureter_morphology | 1.05485469 |
70 | MP0001293_anophthalmia | 1.04658747 |
71 | MP0002069_abnormal_eating/drinking_beha | 1.03040866 |
72 | MP0003938_abnormal_ear_development | 1.01307006 |
73 | MP0005503_abnormal_tendon_morphology | 1.01214600 |
74 | MP0001485_abnormal_pinna_reflex | 0.99654824 |
75 | MP0003119_abnormal_digestive_system | 0.99610088 |
76 | MP0005551_abnormal_eye_electrophysiolog | 0.99333498 |
77 | MP0002233_abnormal_nose_morphology | 0.97270313 |
78 | MP0008961_abnormal_basal_metabolism | 0.95403641 |
79 | MP0002751_abnormal_autonomic_nervous | 0.95272654 |
80 | MP0004145_abnormal_muscle_electrophysio | 0.95065741 |
81 | * MP0002752_abnormal_somatic_nervous | 0.93236570 |
82 | MP0000013_abnormal_adipose_tissue | 0.93201581 |
83 | MP0005195_abnormal_posterior_eye | 0.90910366 |
84 | MP0000569_abnormal_digit_pigmentation | 0.90609396 |
85 | MP0009780_abnormal_chondrocyte_physiolo | 0.86755546 |
86 | MP0005084_abnormal_gallbladder_morpholo | 0.86108306 |
87 | MP0002876_abnormal_thyroid_physiology | 0.84320623 |
88 | MP0003385_abnormal_body_wall | 0.84031986 |
89 | MP0003879_abnormal_hair_cell | 0.83045636 |
90 | MP0005535_abnormal_body_temperature | 0.82937686 |
91 | MP0002229_neurodegeneration | 0.82890195 |
92 | MP0005499_abnormal_olfactory_system | 0.81566898 |
93 | MP0005394_taste/olfaction_phenotype | 0.81566898 |
94 | MP0001963_abnormal_hearing_physiology | 0.80604902 |
95 | MP0003937_abnormal_limbs/digits/tail_de | 0.79330353 |
96 | MP0002928_abnormal_bile_duct | 0.79023847 |
97 | MP0003755_abnormal_palate_morphology | 0.79008184 |
98 | MP0003283_abnormal_digestive_organ | 0.78495143 |
99 | MP0003861_abnormal_nervous_system | 0.78326892 |
100 | MP0003634_abnormal_glial_cell | 0.78312695 |
101 | MP0002102_abnormal_ear_morphology | 0.77883712 |
102 | MP0004885_abnormal_endolymph | 0.77529355 |
103 | MP0008872_abnormal_physiological_respon | 0.77359101 |
104 | MP0009384_cardiac_valve_regurgitation | 0.76868488 |
105 | MP0008995_early_reproductive_senescence | 0.76486798 |
106 | MP0002234_abnormal_pharynx_morphology | 0.75860759 |
107 | MP0003959_abnormal_lean_body | 0.75504760 |
108 | MP0003137_abnormal_impulse_conducting | 0.75354615 |
109 | MP0003633_abnormal_nervous_system | 0.74116329 |
110 | MP0000538_abnormal_urinary_bladder | 0.73370875 |
111 | MP0004085_abnormal_heartbeat | 0.73305414 |
112 | MP0001986_abnormal_taste_sensitivity | 0.73004341 |
113 | MP0004133_heterotaxia | 0.71934503 |
114 | MP0002116_abnormal_craniofacial_bone | 0.71749726 |
115 | MP0002249_abnormal_larynx_morphology | 0.71194408 |
116 | MP0002163_abnormal_gland_morphology | 0.71188453 |
117 | MP0001286_abnormal_eye_development | 0.71022367 |
118 | MP0003631_nervous_system_phenotype | 0.70953196 |
119 | MP0000026_abnormal_inner_ear | 0.70185624 |
120 | MP0009379_abnormal_foot_pigmentation | 0.70069461 |
121 | MP0001299_abnormal_eye_distance/ | 0.69678060 |
122 | MP0005253_abnormal_eye_physiology | 0.69598563 |
123 | MP0000537_abnormal_urethra_morphology | 0.68080521 |
124 | MP0005448_abnormal_energy_balance | 0.68027249 |
125 | MP0005379_endocrine/exocrine_gland_phen | 0.67686111 |
126 | MP0001664_abnormal_digestion | 0.65817263 |
127 | MP0005623_abnormal_meninges_morphology | 0.62091923 |
128 | MP0005409_darkened_coat_color | 0.61546686 |
129 | MP0000462_abnormal_digestive_system | 0.61112236 |
130 | * MP0001943_abnormal_respiration | 0.60924068 |
131 | MP0000604_amyloidosis | 0.56496481 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 5.88800433 |
2 | Myokymia (HP:0002411) | 5.18788430 |
3 | Focal seizures (HP:0007359) | 4.89617354 |
4 | Visual hallucinations (HP:0002367) | 4.57090543 |
5 | Atonic seizures (HP:0010819) | 4.48761764 |
6 | Limb dystonia (HP:0002451) | 4.20751555 |
7 | Absence seizures (HP:0002121) | 3.85854112 |
8 | Epileptic encephalopathy (HP:0200134) | 3.85483429 |
9 | Progressive cerebellar ataxia (HP:0002073) | 3.75759678 |
10 | Febrile seizures (HP:0002373) | 3.67175955 |
11 | Supranuclear gaze palsy (HP:0000605) | 3.58593177 |
12 | * Polyphagia (HP:0002591) | 3.48354287 |
13 | Dialeptic seizures (HP:0011146) | 3.45310709 |
14 | Generalized tonic-clonic seizures (HP:0002069) | 3.29501289 |
15 | Molar tooth sign on MRI (HP:0002419) | 3.18987830 |
16 | Abnormality of midbrain morphology (HP:0002418) | 3.18987830 |
17 | Agitation (HP:0000713) | 3.15404298 |
18 | Ankle clonus (HP:0011448) | 3.10826724 |
19 | True hermaphroditism (HP:0010459) | 3.06802659 |
20 | Gait imbalance (HP:0002141) | 3.03692009 |
21 | Progressive inability to walk (HP:0002505) | 2.99808738 |
22 | Mutism (HP:0002300) | 2.95232046 |
23 | * Abnormal eating behavior (HP:0100738) | 2.92470638 |
24 | Pheochromocytoma (HP:0002666) | 2.90999934 |
25 | Broad-based gait (HP:0002136) | 2.89495133 |
26 | Nephronophthisis (HP:0000090) | 2.86473181 |
27 | Amblyopia (HP:0000646) | 2.85322013 |
28 | Anxiety (HP:0000739) | 2.83997259 |
29 | Septo-optic dysplasia (HP:0100842) | 2.82649501 |
30 | Drooling (HP:0002307) | 2.80610229 |
31 | Excessive salivation (HP:0003781) | 2.80610229 |
32 | Pancreatic fibrosis (HP:0100732) | 2.77277579 |
33 | Neurofibrillary tangles (HP:0002185) | 2.74104850 |
34 | Pachygyria (HP:0001302) | 2.71923159 |
35 | Truncal ataxia (HP:0002078) | 2.69104305 |
36 | Hemiparesis (HP:0001269) | 2.63478287 |
37 | Depression (HP:0000716) | 2.62517551 |
38 | Cerebral inclusion bodies (HP:0100314) | 2.61308151 |
39 | Neuroendocrine neoplasm (HP:0100634) | 2.60171965 |
40 | Lissencephaly (HP:0001339) | 2.57714492 |
41 | Acute necrotizing encephalopathy (HP:0006965) | 2.54228493 |
42 | Hypoplasia of the brainstem (HP:0002365) | 2.52233910 |
43 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.52233910 |
44 | Pancreatic cysts (HP:0001737) | 2.49478710 |
45 | * Failure to thrive in infancy (HP:0001531) | 2.49459966 |
46 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.47091556 |
47 | Congenital primary aphakia (HP:0007707) | 2.42717664 |
48 | Abnormality of the corticospinal tract (HP:0002492) | 2.41756903 |
49 | Medial flaring of the eyebrow (HP:0010747) | 2.39294341 |
50 | Amyotrophic lateral sclerosis (HP:0007354) | 2.36386298 |
51 | Abnormal ciliary motility (HP:0012262) | 2.35249482 |
52 | Spastic gait (HP:0002064) | 2.34606716 |
53 | Hyperthyroidism (HP:0000836) | 2.34199041 |
54 | Urinary urgency (HP:0000012) | 2.33118251 |
55 | Shoulder girdle muscle weakness (HP:0003547) | 2.32660171 |
56 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.30243047 |
57 | EEG with generalized epileptiform discharges (HP:0011198) | 2.30222150 |
58 | Spastic tetraplegia (HP:0002510) | 2.30169203 |
59 | Poor coordination (HP:0002370) | 2.29745308 |
60 | Epileptiform EEG discharges (HP:0011182) | 2.29280175 |
61 | Hyperventilation (HP:0002883) | 2.28717226 |
62 | Retinal dysplasia (HP:0007973) | 2.27572988 |
63 | Progressive macrocephaly (HP:0004481) | 2.27276470 |
64 | * Esotropia (HP:0000565) | 2.26106560 |
65 | Termporal pattern (HP:0011008) | 2.25473544 |
66 | Insidious onset (HP:0003587) | 2.25473544 |
67 | Rib fusion (HP:0000902) | 2.25185713 |
68 | Action tremor (HP:0002345) | 2.24631130 |
69 | Nephrogenic diabetes insipidus (HP:0009806) | 2.24044175 |
70 | Anophthalmia (HP:0000528) | 2.21053094 |
71 | Hypsarrhythmia (HP:0002521) | 2.18573432 |
72 | Inability to walk (HP:0002540) | 2.15495204 |
73 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.15306110 |
74 | Poor eye contact (HP:0000817) | 2.12357006 |
75 | Papilledema (HP:0001085) | 2.12262357 |
76 | Exotropia (HP:0000577) | 2.12164356 |
77 | Abnormality of the renal medulla (HP:0100957) | 2.12066301 |
78 | * Specific learning disability (HP:0001328) | 2.12026398 |
79 | Sclerocornea (HP:0000647) | 2.09288956 |
80 | Dysdiadochokinesis (HP:0002075) | 2.08910796 |
81 | Dysmetria (HP:0001310) | 2.08163724 |
82 | Genital tract atresia (HP:0001827) | 2.07359462 |
83 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.07256266 |
84 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.07256266 |
85 | Vaginal atresia (HP:0000148) | 2.06955010 |
86 | Hypothermia (HP:0002045) | 2.04978010 |
87 | Menstrual irregularities (HP:0000858) | 2.04242652 |
88 | Chronic hepatic failure (HP:0100626) | 2.03374579 |
89 | Lower limb muscle weakness (HP:0007340) | 2.03057557 |
90 | Cortical dysplasia (HP:0002539) | 1.97962322 |
91 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.97606352 |
92 | Absent speech (HP:0001344) | 1.97177006 |
93 | Type II lissencephaly (HP:0007260) | 1.96935594 |
94 | Genetic anticipation (HP:0003743) | 1.96815835 |
95 | Mitochondrial inheritance (HP:0001427) | 1.96732103 |
96 | Optic nerve hypoplasia (HP:0000609) | 1.96229892 |
97 | Postaxial hand polydactyly (HP:0001162) | 1.96131188 |
98 | Hepatoblastoma (HP:0002884) | 1.94402834 |
99 | Fetal akinesia sequence (HP:0001989) | 1.93643300 |
100 | * Narrow forehead (HP:0000341) | 1.93346396 |
101 | Occipital encephalocele (HP:0002085) | 1.93062230 |
102 | Anencephaly (HP:0002323) | 1.92949044 |
103 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.92413721 |
104 | Open mouth (HP:0000194) | 1.92348148 |
105 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.90422041 |
106 | Torticollis (HP:0000473) | 1.90216873 |
107 | Bradykinesia (HP:0002067) | 1.89810235 |
108 | Protruding tongue (HP:0010808) | 1.89083768 |
109 | Impaired social interactions (HP:0000735) | 1.89059310 |
110 | Abnormal social behavior (HP:0012433) | 1.89059310 |
111 | Scanning speech (HP:0002168) | 1.89004420 |
112 | Left ventricular hypertrophy (HP:0001712) | 1.87422593 |
113 | Delayed gross motor development (HP:0002194) | 1.87085682 |
114 | Broad foot (HP:0001769) | 1.87045446 |
115 | Oligodactyly (hands) (HP:0001180) | 1.85998247 |
116 | Cystic liver disease (HP:0006706) | 1.85581823 |
117 | Absent septum pellucidum (HP:0001331) | 1.85315062 |
118 | Maternal diabetes (HP:0009800) | 1.84917168 |
119 | Akinesia (HP:0002304) | 1.84789062 |
120 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.84010923 |
121 | Anomalous pulmonary venous return (HP:0010772) | 1.83060754 |
122 | Abnormality of salivation (HP:0100755) | 1.82643719 |
123 | * Hypoventilation (HP:0002791) | 1.82593768 |
124 | Shawl scrotum (HP:0000049) | 1.82143601 |
125 | Generalized myoclonic seizures (HP:0002123) | 1.82068301 |
126 | Male pseudohermaphroditism (HP:0000037) | 1.80923611 |
127 | * Psychosis (HP:0000709) | 1.80849162 |
128 | Focal dystonia (HP:0004373) | 1.80126052 |
129 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.80002188 |
130 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.80002188 |
131 | Megalencephaly (HP:0001355) | 1.79412554 |
132 | Diplopia (HP:0000651) | 1.77232093 |
133 | Abnormality of binocular vision (HP:0011514) | 1.77232093 |
134 | Myotonia (HP:0002486) | 1.76902422 |
135 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.76599439 |
136 | Congenital stationary night blindness (HP:0007642) | 1.73891118 |
137 | Status epilepticus (HP:0002133) | 1.73071177 |
138 | Humeroradial synostosis (HP:0003041) | 1.71362904 |
139 | Synostosis involving the elbow (HP:0003938) | 1.71362904 |
140 | Hypoplasia of the corpus callosum (HP:0002079) | 1.67816071 |
141 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.66843602 |
142 | Abnormality of the pulmonary veins (HP:0011718) | 1.66226342 |
143 | Acute encephalopathy (HP:0006846) | 1.65973279 |
144 | * Poor suck (HP:0002033) | 1.62892757 |
145 | Ulnar claw (HP:0001178) | 1.62181227 |
146 | Increased corneal curvature (HP:0100692) | 1.62145936 |
147 | Keratoconus (HP:0000563) | 1.62145936 |
148 | Morphological abnormality of the middle ear (HP:0008609) | 1.61228157 |
149 | * Micropenis (HP:0000054) | 1.60224912 |
150 | Hyperglycinemia (HP:0002154) | 1.59153358 |
151 | Abnormality of the aortic arch (HP:0012303) | 1.58390670 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MARK1 | 4.45284355 |
2 | MAP3K9 | 4.00454155 |
3 | NTRK3 | 3.74956465 |
4 | MAP3K12 | 3.34258777 |
5 | MAP3K4 | 2.95366199 |
6 | NTRK2 | 2.90917244 |
7 | MINK1 | 2.73058654 |
8 | MAP2K7 | 2.49856101 |
9 | PINK1 | 2.48991060 |
10 | PNCK | 2.42656317 |
11 | CASK | 2.26171647 |
12 | MAPK13 | 2.14133298 |
13 | UHMK1 | 2.01292925 |
14 | MAP2K4 | 1.97613345 |
15 | EPHA4 | 1.97607871 |
16 | MAPK15 | 1.93692792 |
17 | KSR1 | 1.88240917 |
18 | ARAF | 1.86349437 |
19 | MAP4K2 | 1.85927418 |
20 | WNK3 | 1.74042335 |
21 | TNIK | 1.73605988 |
22 | PAK6 | 1.72751973 |
23 | PHKG1 | 1.52308033 |
24 | PHKG2 | 1.52308033 |
25 | BCR | 1.49828397 |
26 | CDK19 | 1.48444169 |
27 | SIK2 | 1.48367763 |
28 | NTRK1 | 1.45987383 |
29 | DYRK2 | 1.43190971 |
30 | CDK5 | 1.38847978 |
31 | KSR2 | 1.32420923 |
32 | GRK5 | 1.32263093 |
33 | PLK2 | 1.26363153 |
34 | SIK3 | 1.25822165 |
35 | PAK3 | 1.25324256 |
36 | DYRK3 | 1.16900562 |
37 | NME1 | 1.15980438 |
38 | DAPK2 | 1.15880549 |
39 | LATS2 | 1.15769133 |
40 | TYRO3 | 1.14685672 |
41 | CSNK1G2 | 1.12456900 |
42 | STK16 | 1.10625122 |
43 | CDK14 | 1.09637938 |
44 | CDK18 | 1.08961944 |
45 | TRIM28 | 1.07807272 |
46 | GRK7 | 1.06002664 |
47 | CAMK2A | 1.04508925 |
48 | LIMK1 | 1.02632745 |
49 | PRKCG | 1.01743904 |
50 | CDK15 | 1.01697713 |
51 | GRK1 | 1.01282605 |
52 | DYRK1B | 1.00615221 |
53 | CSNK1G3 | 0.98516548 |
54 | DYRK1A | 0.92815370 |
55 | BCKDK | 0.90750777 |
56 | CDK11A | 0.89997965 |
57 | TIE1 | 0.83166373 |
58 | OXSR1 | 0.82745584 |
59 | FES | 0.80958759 |
60 | ERBB3 | 0.80599119 |
61 | ADRBK2 | 0.80538403 |
62 | EPHA3 | 0.80073648 |
63 | CAMK2B | 0.80012071 |
64 | ADRBK1 | 0.76861018 |
65 | FER | 0.76844009 |
66 | EPHB2 | 0.72034975 |
67 | CAMKK2 | 0.71576665 |
68 | DMPK | 0.71336264 |
69 | DAPK1 | 0.71074465 |
70 | LMTK2 | 0.70869598 |
71 | PRKCH | 0.68880165 |
72 | CAMK1G | 0.68799452 |
73 | IRAK2 | 0.68654609 |
74 | MAP3K11 | 0.67580752 |
75 | BMPR1B | 0.67573824 |
76 | FGFR2 | 0.64231850 |
77 | BRAF | 0.63344326 |
78 | SGK494 | 0.63106792 |
79 | SGK223 | 0.63106792 |
80 | PRKD3 | 0.62937369 |
81 | CAMKK1 | 0.62519624 |
82 | RET | 0.59649893 |
83 | SGK2 | 0.59495833 |
84 | PRKCE | 0.57628632 |
85 | PRPF4B | 0.57318772 |
86 | PRKCZ | 0.57258956 |
87 | CSNK1G1 | 0.56681162 |
88 | MAP3K13 | 0.56248790 |
89 | TNK2 | 0.55302027 |
90 | CAMK1 | 0.54839935 |
91 | CAMK2G | 0.54117946 |
92 | RIPK4 | 0.52969045 |
93 | MKNK2 | 0.51495480 |
94 | CAMK2D | 0.51310063 |
95 | CSNK1A1L | 0.50935068 |
96 | STK11 | 0.49087510 |
97 | FGR | 0.49053177 |
98 | PRKG1 | 0.48401043 |
99 | PKN1 | 0.48031294 |
100 | MARK2 | 0.47432835 |
101 | CSNK1A1 | 0.47176486 |
102 | ROCK2 | 0.47117525 |
103 | DDR2 | 0.45680914 |
104 | RPS6KA2 | 0.44858413 |
105 | WNK4 | 0.44349524 |
106 | RAF1 | 0.42048370 |
107 | VRK1 | 0.42015710 |
108 | MAP3K2 | 0.41636212 |
109 | INSRR | 0.39915709 |
110 | ABL2 | 0.39400993 |
111 | RPS6KA3 | 0.39218039 |
112 | MAPKAPK5 | 0.38765376 |
113 | PRKAA1 | 0.38105066 |
114 | ERBB2 | 0.37652309 |
115 | PRKACB | 0.37619687 |
116 | SGK1 | 0.37553366 |
117 | PRKD2 | 0.36681567 |
118 | PRKACA | 0.35977689 |
119 | CSNK1D | 0.34360009 |
120 | MAP3K1 | 0.34074573 |
121 | MAPK9 | 0.33312857 |
122 | FYN | 0.32834882 |
123 | MAP2K1 | 0.32010555 |
124 | STK39 | 0.31953440 |
125 | ROCK1 | 0.31894990 |
126 | STK38 | 0.31361819 |
127 | PTK2B | 0.30838511 |
128 | CSNK1E | 0.30801299 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 4.20507497 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.41707751 |
3 | GABAergic synapse_Homo sapiens_hsa04727 | 2.83105462 |
4 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.63826512 |
5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.51172849 |
6 | Morphine addiction_Homo sapiens_hsa05032 | 2.38101713 |
7 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.27486876 |
8 | Circadian entrainment_Homo sapiens_hsa04713 | 2.27132230 |
9 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.25982486 |
10 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.20832897 |
11 | Parkinsons disease_Homo sapiens_hsa05012 | 2.16505635 |
12 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.16096088 |
13 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.16074462 |
14 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 2.14880615 |
15 | Olfactory transduction_Homo sapiens_hsa04740 | 2.11729520 |
16 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.07388619 |
17 | Cocaine addiction_Homo sapiens_hsa05030 | 2.06369549 |
18 | Taste transduction_Homo sapiens_hsa04742 | 2.02836874 |
19 | Long-term potentiation_Homo sapiens_hsa04720 | 2.02728818 |
20 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.99977523 |
21 | Insulin secretion_Homo sapiens_hsa04911 | 1.83082339 |
22 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.80098719 |
23 | Alzheimers disease_Homo sapiens_hsa05010 | 1.76830682 |
24 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.76624005 |
25 | Long-term depression_Homo sapiens_hsa04730 | 1.70326328 |
26 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.70189967 |
27 | Salivary secretion_Homo sapiens_hsa04970 | 1.57176480 |
28 | Renin secretion_Homo sapiens_hsa04924 | 1.54791651 |
29 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.53679394 |
30 | Axon guidance_Homo sapiens_hsa04360 | 1.53172612 |
31 | Gap junction_Homo sapiens_hsa04540 | 1.49143619 |
32 | Huntingtons disease_Homo sapiens_hsa05016 | 1.48885273 |
33 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.41435598 |
34 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.41433173 |
35 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.41011025 |
36 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.40948909 |
37 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.40679227 |
38 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.35722215 |
39 | Protein export_Homo sapiens_hsa03060 | 1.29327197 |
40 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.28949725 |
41 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.28943083 |
42 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.24169901 |
43 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.23796014 |
44 | Ribosome_Homo sapiens_hsa03010 | 1.15453410 |
45 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.13286582 |
46 | Melanogenesis_Homo sapiens_hsa04916 | 1.08716789 |
47 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.05831497 |
48 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.03971828 |
49 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.03841027 |
50 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.00659071 |
51 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.00278581 |
52 | Phototransduction_Homo sapiens_hsa04744 | 0.97571795 |
53 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.92109079 |
54 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.90176735 |
55 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.85870976 |
56 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.85135527 |
57 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.85114340 |
58 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.84604770 |
59 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.83394785 |
60 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.82356754 |
61 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.78997140 |
62 | Alcoholism_Homo sapiens_hsa05034 | 0.78808747 |
63 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.77701963 |
64 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.76169620 |
65 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.75664370 |
66 | Prion diseases_Homo sapiens_hsa05020 | 0.71578621 |
67 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.70569762 |
68 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.70468645 |
69 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.68929386 |
70 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.66990377 |
71 | Glioma_Homo sapiens_hsa05214 | 0.66456261 |
72 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.64338837 |
73 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.64102392 |
74 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.62938835 |
75 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.62373586 |
76 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.61519514 |
77 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.61335850 |
78 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.61111346 |
79 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.60468619 |
80 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.60285456 |
81 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.59600632 |
82 | Sulfur relay system_Homo sapiens_hsa04122 | 0.59095236 |
83 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.58245088 |
84 | Peroxisome_Homo sapiens_hsa04146 | 0.56626382 |
85 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.56133857 |
86 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.55511570 |
87 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.55304972 |
88 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.54453220 |
89 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.53639976 |
90 | Phagosome_Homo sapiens_hsa04145 | 0.52754679 |
91 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.52156930 |
92 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.51435830 |
93 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.51298670 |
94 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.50544303 |
95 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.50306731 |
96 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.49744594 |
97 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.48934367 |
98 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.48724666 |
99 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.48420989 |
100 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.48224740 |
101 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.47483920 |
102 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.47050889 |
103 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.46233815 |
104 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.45805803 |
105 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.45179764 |
106 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.44928516 |
107 | Tight junction_Homo sapiens_hsa04530 | 0.44884965 |
108 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.44691067 |
109 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.42200910 |
110 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.41731726 |
111 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.41627884 |
112 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.41292276 |
113 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.40960902 |
114 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.40648419 |
115 | Bile secretion_Homo sapiens_hsa04976 | 0.39773929 |
116 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.38586276 |
117 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.36977779 |
118 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.36443704 |
119 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.36077335 |
120 | Metabolic pathways_Homo sapiens_hsa01100 | 0.35669612 |
121 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.35622008 |
122 | Circadian rhythm_Homo sapiens_hsa04710 | 0.34626661 |
123 | Colorectal cancer_Homo sapiens_hsa05210 | 0.34575055 |
124 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.33775287 |
125 | Endometrial cancer_Homo sapiens_hsa05213 | 0.33240106 |
126 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.32559379 |
127 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.30941921 |
128 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.27906849 |
129 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.27522992 |
130 | Endocytosis_Homo sapiens_hsa04144 | 0.25545981 |
131 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.22647611 |
132 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.22068963 |
133 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.21107280 |
134 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.20014134 |