NDNF

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1glomerular basement membrane development (GO:0032836)8.17556061
2detection of light stimulus involved in sensory perception (GO:0050962)6.09338377
3detection of light stimulus involved in visual perception (GO:0050908)6.09338377
4response to pheromone (GO:0019236)5.97903444
5positive regulation of synapse maturation (GO:0090129)5.72749862
6retinal cone cell development (GO:0046549)5.71292872
7positive regulation of dendritic spine morphogenesis (GO:0061003)5.68747027
8negative regulation of cytosolic calcium ion concentration (GO:0051481)5.51569437
9camera-type eye morphogenesis (GO:0048593)5.42520245
10radial glial cell differentiation (GO:0060019)5.33551660
11retinal rod cell development (GO:0046548)5.27491247
12otic vesicle formation (GO:0030916)5.26391493
13regulation of synapse maturation (GO:0090128)4.95778033
14cellular potassium ion homeostasis (GO:0030007)4.84349735
15regulation of branching involved in prostate gland morphogenesis (GO:0060687)4.67173570
16G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.63007198
17limb bud formation (GO:0060174)4.61590020
18lung epithelium development (GO:0060428)4.58996789
19embryonic camera-type eye development (GO:0031076)4.56617907
20negative regulation of Rho protein signal transduction (GO:0035024)4.55872871
21synaptic vesicle exocytosis (GO:0016079)4.37497932
22protein localization to synapse (GO:0035418)4.37371416
23embryonic retina morphogenesis in camera-type eye (GO:0060059)4.28306369
24neurotransmitter-gated ion channel clustering (GO:0072578)4.26638580
25skeletal muscle adaptation (GO:0043501)4.13849433
26cilium or flagellum-dependent cell motility (GO:0001539)4.11724273
27protein localization to cell surface (GO:0034394)4.05276639
28positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr4.04308633
29positive regulation of CREB transcription factor activity (GO:0032793)4.03716198
30eye photoreceptor cell development (GO:0042462)4.02126418
31induction of positive chemotaxis (GO:0050930)4.00342297
32vocalization behavior (GO:0071625)3.99136830
33neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.98339085
34regulation of bile acid biosynthetic process (GO:0070857)3.97651548
35keratan sulfate catabolic process (GO:0042340)3.97120163
36photoreceptor cell development (GO:0042461)3.93192157
37apical protein localization (GO:0045176)3.92703574
38negative regulation of stress fiber assembly (GO:0051497)3.92483021
39myelination in peripheral nervous system (GO:0022011)3.87806648
40peripheral nervous system axon ensheathment (GO:0032292)3.87806648
41cellular response to nitric oxide (GO:0071732)3.84751336
42regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.81594644
43potassium ion homeostasis (GO:0055075)3.79640377
44innervation (GO:0060384)3.75540995
45regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 3.74140351
46mating behavior (GO:0007617)3.72822291
47genitalia morphogenesis (GO:0035112)3.72540929
48negative regulation of complement activation (GO:0045916)3.71063917
49urinary tract smooth muscle contraction (GO:0014848)3.68210663
50axonemal dynein complex assembly (GO:0070286)3.67609121
51epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.67337187
52regulation of sarcomere organization (GO:0060297)3.57958114
53positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.56316618
54mesenchymal-epithelial cell signaling (GO:0060638)3.56211730
55layer formation in cerebral cortex (GO:0021819)3.56201560
56gonadal mesoderm development (GO:0007506)3.51041760
57regulation of short-term neuronal synaptic plasticity (GO:0048172)3.50674749
58cilium movement (GO:0003341)3.45418789
59lung secretory cell differentiation (GO:0061140)3.45197790
60surfactant homeostasis (GO:0043129)3.41336344
61substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.37052755
62substrate-independent telencephalic tangential migration (GO:0021826)3.37052755
63striatum development (GO:0021756)3.36806398
64cell migration involved in heart development (GO:0060973)3.35186066
65regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.32137650
66axis elongation (GO:0003401)3.32072546
67lymphangiogenesis (GO:0001946)3.30295682
68sequestering of extracellular ligand from receptor (GO:0035581)3.30194283
69organ growth (GO:0035265)3.29645827
70cell differentiation involved in metanephros development (GO:0072202)3.27365015
71muscle cell fate commitment (GO:0042693)3.26867480
72regulation of non-canonical Wnt signaling pathway (GO:2000050)3.26762592
73gamma-aminobutyric acid signaling pathway (GO:0007214)3.26052023
74embryonic digestive tract morphogenesis (GO:0048557)3.25592061
75nonmotile primary cilium assembly (GO:0035058)3.25115115
76negative regulation of protein activation cascade (GO:2000258)3.21645340
77neuron cell-cell adhesion (GO:0007158)3.21149427
78epithelial cilium movement (GO:0003351)3.20789750
79synaptic vesicle endocytosis (GO:0048488)3.20749216
80secondary heart field specification (GO:0003139)3.20631518
81heart field specification (GO:0003128)3.20631518
82bicarbonate transport (GO:0015701)3.19838057
83negative regulation of actin filament bundle assembly (GO:0032232)3.19305426
84regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.16364444
85regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.16364444
86dentate gyrus development (GO:0021542)3.16173186
87branch elongation of an epithelium (GO:0060602)3.16059979
88glomerular filtration (GO:0003094)3.15196061
89atrial cardiac muscle cell action potential (GO:0086014)3.14020962
90one-carbon compound transport (GO:0019755)3.13443950
91lateral ventricle development (GO:0021670)3.13231650
92lung vasculature development (GO:0060426)3.12142319
93cerebellar granule cell differentiation (GO:0021707)3.10602051
94metanephric nephron tubule development (GO:0072234)3.08138446
95metanephric tubule development (GO:0072170)3.08138446
96phosphate ion transmembrane transport (GO:0035435)3.06858881
97kidney morphogenesis (GO:0060993)3.05517470
98motile cilium assembly (GO:0044458)3.04535638
99endocrine hormone secretion (GO:0060986)3.01025226
100negative regulation of humoral immune response (GO:0002921)3.00372043
101synaptic vesicle maturation (GO:0016188)3.00333354
102synapse assembly (GO:0007416)2.99629850
103phosphate ion homeostasis (GO:0055062)2.96747349
104trivalent inorganic anion homeostasis (GO:0072506)2.96747349
105myoblast fusion (GO:0007520)2.96399330
106positive regulation of dendritic spine development (GO:0060999)2.95763255
107cerebellar Purkinje cell differentiation (GO:0021702)2.95528603
108prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.92659004
109organ induction (GO:0001759)2.92559741
110non-canonical Wnt signaling pathway (GO:0035567)2.91764709
111auditory behavior (GO:0031223)2.91247846
112neuronal ion channel clustering (GO:0045161)2.90725777
113regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.89626335
114response to histamine (GO:0034776)2.88918966
115establishment of nucleus localization (GO:0040023)2.88890398
116behavioral response to ethanol (GO:0048149)2.88677634
117collagen catabolic process (GO:0030574)2.88583827
118left/right axis specification (GO:0070986)2.87941690
119regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.87728021
120glutamate secretion (GO:0014047)2.87412675
121positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.84838595
122mesenchymal cell differentiation (GO:0048762)2.84373805
123positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.82811918
124regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.82745999
125renal filtration (GO:0097205)2.82650397
126mesonephros development (GO:0001823)2.82367287
127prepulse inhibition (GO:0060134)2.81386019
128collagen metabolic process (GO:0032963)2.80931177
129catecholamine transport (GO:0051937)2.80758078
130regulation of synaptic vesicle exocytosis (GO:2000300)2.78423041
131smooth muscle cell differentiation (GO:0051145)2.78231230
132negative regulation of systemic arterial blood pressure (GO:0003085)2.78121255
133positive regulation of endothelial cell differentiation (GO:0045603)2.78023822
134sodium ion homeostasis (GO:0055078)2.77618690
135chemical homeostasis within a tissue (GO:0048875)2.77410233
136metanephric nephron epithelium development (GO:0072243)2.77263086
137neuron projection extension involved in neuron projection guidance (GO:1902284)2.76952566
138axon extension involved in axon guidance (GO:0048846)2.76952566
139regulation of synaptic transmission, glutamatergic (GO:0051966)2.76777727
140membrane hyperpolarization (GO:0060081)2.76638509
141positive regulation of cell junction assembly (GO:1901890)2.76401306
142positive regulation of focal adhesion assembly (GO:0051894)2.76401306
143synaptic vesicle docking involved in exocytosis (GO:0016081)2.75517298
144cell proliferation involved in kidney development (GO:0072111)2.74298645
145branching involved in prostate gland morphogenesis (GO:0060442)2.73138424
146lung alveolus development (GO:0048286)2.72679797
147phosphate ion transport (GO:0006817)2.72334019
148positive regulation of gastrulation (GO:2000543)2.72135114
149lung-associated mesenchyme development (GO:0060484)2.71188741
150photoreceptor cell maintenance (GO:0045494)2.71092892
151lateral sprouting from an epithelium (GO:0060601)2.71079856
152collagen fibril organization (GO:0030199)2.70275577
153cellular response to reactive nitrogen species (GO:1902170)2.69873020
154positive regulation of dendrite morphogenesis (GO:0050775)2.69030820
155hyperosmotic salinity response (GO:0042538)2.68975260
156establishment of synaptic vesicle localization (GO:0097480)2.68491191
157synaptic vesicle transport (GO:0048489)2.68491191
158righting reflex (GO:0060013)2.68386751
159multicellular organismal macromolecule metabolic process (GO:0044259)2.67162389
160relaxation of smooth muscle (GO:0044557)2.67108330
161multicellular organismal catabolic process (GO:0044243)2.66838659
162calcium ion import (GO:0070509)2.65946921
163eye morphogenesis (GO:0048592)2.65739005
164regulation of vasculogenesis (GO:2001212)2.65433907
165presynaptic membrane assembly (GO:0097105)2.64721834
166organ formation (GO:0048645)2.64680970
167lymph vessel development (GO:0001945)2.63376950
168blood vessel remodeling (GO:0001974)2.63179125
169white fat cell differentiation (GO:0050872)2.62972281
170outflow tract septum morphogenesis (GO:0003148)2.60801429
171axoneme assembly (GO:0035082)2.60254412
172homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.59196370
173rhodopsin mediated signaling pathway (GO:0016056)2.58343471
174metanephric epithelium development (GO:0072207)2.57277408
175specification of organ identity (GO:0010092)2.57036412
176asymmetric protein localization (GO:0008105)2.56947172
177multicellular organismal metabolic process (GO:0044236)2.54717212
178regulation of dendritic spine morphogenesis (GO:0061001)2.54385636
179peristalsis (GO:0030432)2.54171547
180regulation of neurotransmitter uptake (GO:0051580)2.53709909
181venous blood vessel morphogenesis (GO:0048845)2.53211378
182respiratory gaseous exchange (GO:0007585)2.53014243
183positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.52764042
184negative regulation of osteoblast proliferation (GO:0033689)2.52397342
185positive regulation of adherens junction organization (GO:1903393)2.51182797
186postsynaptic membrane organization (GO:0001941)2.51131342
187regulation of organ formation (GO:0003156)2.51100176
188glutamate receptor signaling pathway (GO:0007215)2.50351619
189neurotransmitter secretion (GO:0007269)2.48719786
190negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.48062706
191cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.47972032
192potassium ion export (GO:0071435)2.47525163

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human4.14927374
2GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.65512183
3GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.24227035
4AR_21572438_ChIP-Seq_LNCaP_Human2.72006923
5IGF1R_20145208_ChIP-Seq_DFB_Human2.63603248
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.40279218
7SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.32166695
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.30107103
9SMAD_19615063_ChIP-ChIP_OVARY_Human2.30090165
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.29410789
11EED_16625203_ChIP-ChIP_MESCs_Mouse2.22267211
12SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.10461296
13PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human2.07367799
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.03030287
15ZFP57_27257070_Chip-Seq_ESCs_Mouse2.01681351
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.01208315
17PIAS1_25552417_ChIP-Seq_VCAP_Human1.98408603
18EZH2_22144423_ChIP-Seq_EOC_Human1.97692734
19CTBP1_25329375_ChIP-Seq_LNCAP_Human1.97615072
20EZH2_18974828_ChIP-Seq_MESCs_Mouse1.96719259
21RNF2_18974828_ChIP-Seq_MESCs_Mouse1.96719259
22SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.96181010
23SMAD4_21799915_ChIP-Seq_A2780_Human1.95645240
24ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.95344530
25CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.94228314
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.93548457
27MTF2_20144788_ChIP-Seq_MESCs_Mouse1.90315017
28DROSHA_22980978_ChIP-Seq_HELA_Human1.86938769
29SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.85480218
30SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.82196687
31RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.80850809
32RNF2_27304074_Chip-Seq_ESCs_Mouse1.80509968
33FUS_26573619_Chip-Seq_HEK293_Human1.80048912
34POU3F2_20337985_ChIP-ChIP_501MEL_Human1.79681936
35BMI1_23680149_ChIP-Seq_NPCS_Mouse1.78396648
36P300_19829295_ChIP-Seq_ESCs_Human1.74041565
37PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.68310469
38EZH2_27294783_Chip-Seq_ESCs_Mouse1.64371079
39TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.63390498
40VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.62735308
41AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.54094749
42ZNF217_24962896_ChIP-Seq_MCF-7_Human1.53849401
43SUZ12_27294783_Chip-Seq_ESCs_Mouse1.53349799
44SMAD3_21741376_ChIP-Seq_EPCs_Human1.50132479
45STAT3_23295773_ChIP-Seq_U87_Human1.49891103
46TAF15_26573619_Chip-Seq_HEK293_Human1.49152281
47ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.48414158
48CJUN_26792858_Chip-Seq_BT549_Human1.47664113
49REST_21632747_ChIP-Seq_MESCs_Mouse1.44619391
50TOP2B_26459242_ChIP-Seq_MCF-7_Human1.42982399
51CBX2_27304074_Chip-Seq_ESCs_Mouse1.41381057
52TCF4_23295773_ChIP-Seq_U87_Human1.38585784
53AHR_22903824_ChIP-Seq_MCF-7_Human1.37608476
54OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35995699
55IKZF1_21737484_ChIP-ChIP_HCT116_Human1.35523372
56CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.35412857
57SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35165770
58CDX2_19796622_ChIP-Seq_MESCs_Mouse1.34416600
59AR_25329375_ChIP-Seq_VCAP_Human1.34204564
60P53_22127205_ChIP-Seq_FIBROBLAST_Human1.32753803
61ESR1_21235772_ChIP-Seq_MCF-7_Human1.32356787
62EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.29907406
63NR3C1_21868756_ChIP-Seq_MCF10A_Human1.29599326
64ER_23166858_ChIP-Seq_MCF-7_Human1.29047565
65BCAT_22108803_ChIP-Seq_LS180_Human1.28766192
66TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.28521718
67ARNT_22903824_ChIP-Seq_MCF-7_Human1.28363203
68TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.27188442
69RBPJ_22232070_ChIP-Seq_NCS_Mouse1.26639747
70NFIB_24661679_ChIP-Seq_LUNG_Mouse1.25268399
71RARG_19884340_ChIP-ChIP_MEFs_Mouse1.25136354
72FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.24315852
73SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24222690
74NANOG_18555785_Chip-Seq_ESCs_Mouse1.23827340
75FLI1_27457419_Chip-Seq_LIVER_Mouse1.23719978
76SMAD3_21741376_ChIP-Seq_HESCs_Human1.23188541
77SOX2_21211035_ChIP-Seq_LN229_Gbm1.23021062
78POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.21219810
79TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21219810
80TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.20121107
81MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.19083656
82TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.18857383
83EWS_26573619_Chip-Seq_HEK293_Human1.18709446
84FOXM1_26456572_ChIP-Seq_MCF-7_Human1.18692487
85TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.18432640
86SMAD4_21741376_ChIP-Seq_HESCs_Human1.17897235
87YAP1_20516196_ChIP-Seq_MESCs_Mouse1.17104730
88ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.17028117
89UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.16331129
90CTNNB1_20460455_ChIP-Seq_HCT116_Human1.15983291
91SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.14784098
92PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.14133710
93ISL1_27105846_Chip-Seq_CPCs_Mouse1.12330618
94NRF2_20460467_ChIP-Seq_MEFs_Mouse1.11909966
95NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.11909966
96TP53_16413492_ChIP-PET_HCT116_Human1.11052487
97RXR_22108803_ChIP-Seq_LS180_Human1.09914836
98SALL1_21062744_ChIP-ChIP_HESCs_Human1.09377373
99EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.09320828
100PCGF2_27294783_Chip-Seq_ESCs_Mouse1.09037235
101E2F1_18555785_Chip-Seq_ESCs_Mouse1.09019279
102EP300_21415370_ChIP-Seq_HL-1_Mouse1.08633076
103SOX9_24532713_ChIP-Seq_HFSC_Mouse1.08080148
104AR_19668381_ChIP-Seq_PC3_Human1.07560585
105FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.07024798
106RUNX2_22187159_ChIP-Seq_PCA_Human1.05948669
107MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05854270
108LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05510111
109SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05389409
110WT1_25993318_ChIP-Seq_PODOCYTE_Human1.05349876
111TRIM28_21343339_ChIP-Seq_HEK293_Human1.05271812
112RING1B_27294783_Chip-Seq_NPCs_Mouse1.05050785
113TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04234683
114STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.04098564
115HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.03799254
116BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.02871161
117BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.02476770
118TP53_18474530_ChIP-ChIP_U2OS_Human1.02413078
119TP53_20018659_ChIP-ChIP_R1E_Mouse1.02233123
120IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.02100454
121CBP_20019798_ChIP-Seq_JUKART_Human1.02100454
122RNF2_27304074_Chip-Seq_NSC_Mouse1.01063953
123PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.00842968
124PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00749928
125CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.00548302
126RING1B_27294783_Chip-Seq_ESCs_Mouse0.99733092
127NR3C1_23031785_ChIP-Seq_PC12_Mouse0.99716197
128KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.99621679
129TBL1_22424771_ChIP-Seq_293T_Human0.99531031
130HIF1A_21447827_ChIP-Seq_MCF-7_Human0.98973920
131CMYC_18555785_Chip-Seq_ESCs_Mouse0.97334096
132CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.96727156
133TCF4_18268006_ChIP-ChIP_LS174T_Human0.95822830

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003878_abnormal_ear_physiology5.64940273
2MP0005377_hearing/vestibular/ear_phenot5.64940273
3MP0005551_abnormal_eye_electrophysiolog4.71703700
4MP0010368_abnormal_lymphatic_system3.87050712
5MP0001188_hyperpigmentation3.85634111
6MP0002090_abnormal_vision3.44980889
7MP0001984_abnormal_olfaction3.40408257
8MP0008438_abnormal_cutaneous_collagen3.21952469
9MP0003880_abnormal_central_pattern2.88845605
10MP0005248_abnormal_Harderian_gland2.75701598
11MP0005275_abnormal_skin_tensile2.73807663
12MP0006072_abnormal_retinal_apoptosis2.69694992
13MP0004782_abnormal_surfactant_physiolog2.60487693
14MP0005409_darkened_coat_color2.50036811
15MP0002132_abnormal_respiratory_system2.47413469
16MP0005253_abnormal_eye_physiology2.34234027
17MP0001502_abnormal_circadian_rhythm2.27696961
18MP0002295_abnormal_pulmonary_circulatio2.18363289
19MP0005187_abnormal_penis_morphology2.17610304
20MP0003950_abnormal_plasma_membrane2.12096097
21MP0010386_abnormal_urinary_bladder2.10814323
22MP0005423_abnormal_somatic_nervous2.09948507
23MP0004233_abnormal_muscle_weight2.09289164
24MP0001486_abnormal_startle_reflex2.03694026
25MP0009046_muscle_twitch1.99318027
26MP0000566_synostosis1.99201159
27MP0004885_abnormal_endolymph1.98150765
28MP0001879_abnormal_lymphatic_vessel1.97928090
29MP0001177_atelectasis1.88923456
30MP0004272_abnormal_basement_membrane1.86776456
31MP0001346_abnormal_lacrimal_gland1.84693584
32MP0005503_abnormal_tendon_morphology1.79655163
33MP0008004_abnormal_stomach_pH1.78261303
34MP0005195_abnormal_posterior_eye1.78141672
35MP0006292_abnormal_olfactory_placode1.77084204
36MP0008775_abnormal_heart_ventricle1.73688184
37MP0000516_abnormal_urinary_system1.72926093
38MP0005367_renal/urinary_system_phenotyp1.72926093
39MP0003635_abnormal_synaptic_transmissio1.72379030
40MP0001542_abnormal_bone_strength1.62955693
41MP0008995_early_reproductive_senescence1.62562592
42MP0005595_abnormal_vascular_smooth1.60643182
43MP0005257_abnormal_intraocular_pressure1.58215311
44MP0000534_abnormal_ureter_morphology1.56375739
45MP0002572_abnormal_emotion/affect_behav1.48840645
46MP0002822_catalepsy1.45059891
47MP0001756_abnormal_urination1.44359024
48MP0002064_seizures1.43675522
49MP0002184_abnormal_innervation1.41495940
50MP0000569_abnormal_digit_pigmentation1.41429181
51MP0002272_abnormal_nervous_system1.40853969
52MP0005508_abnormal_skeleton_morphology1.39681007
53MP0002063_abnormal_learning/memory/cond1.38957325
54MP0009780_abnormal_chondrocyte_physiolo1.38774383
55MP0002557_abnormal_social/conspecific_i1.37184513
56MP0003115_abnormal_respiratory_system1.34740140
57MP0002067_abnormal_sensory_capabilities1.33116376
58MP0000026_abnormal_inner_ear1.31113312
59MP0001968_abnormal_touch/_nociception1.30777262
60MP0005391_vision/eye_phenotype1.29723893
61MP0009745_abnormal_behavioral_response1.28880904
62MP0002752_abnormal_somatic_nervous1.28290647
63MP0002909_abnormal_adrenal_gland1.26507892
64MP0000631_abnormal_neuroendocrine_gland1.25895985
65MP0003890_abnormal_embryonic-extraembry1.25742098
66MP0004742_abnormal_vestibular_system1.25436530
67MP0002882_abnormal_neuron_morphology1.25128280
68MP0002282_abnormal_trachea_morphology1.23543942
69MP0002229_neurodegeneration1.21057441
70MP0002108_abnormal_muscle_morphology1.20840210
71MP0001299_abnormal_eye_distance/1.18749608
72MP0010030_abnormal_orbit_morphology1.15866970
73MP0004043_abnormal_pH_regulation1.14131721
74MP0002734_abnormal_mechanical_nocicepti1.11836599
75MP0002938_white_spotting1.10505045
76MP0004859_abnormal_synaptic_plasticity1.10288686
77MP0004133_heterotaxia1.05975865
78MP0003091_abnormal_cell_migration1.04774089
79MP0009250_abnormal_appendicular_skeleto1.04446818
80MP0003279_aneurysm1.04005665
81MP0002102_abnormal_ear_morphology1.02325315
82MP0000767_abnormal_smooth_muscle1.01292841
83MP0003937_abnormal_limbs/digits/tail_de1.00761554
84MP0004215_abnormal_myocardial_fiber0.99951285
85MP0005410_abnormal_fertilization0.99812780
86MP0009384_cardiac_valve_regurgitation0.99744263
87MP0003938_abnormal_ear_development0.99737604
88MP0008569_lethality_at_weaning0.98465012
89MP0004924_abnormal_behavior0.98094891
90MP0005386_behavior/neurological_phenoty0.98094891
91MP0001958_emphysema0.97707165
92MP0001293_anophthalmia0.97463344
93MP0005646_abnormal_pituitary_gland0.97405144
94MP0002277_abnormal_respiratory_mucosa0.97328423
95MP0005193_abnormal_anterior_eye0.95963103
96MP0003385_abnormal_body_wall0.94260421
97MP0003941_abnormal_skin_development0.93800623
98MP0001963_abnormal_hearing_physiology0.93373163
99MP0002233_abnormal_nose_morphology0.92228888
100MP0001661_extended_life_span0.92194682
101MP0003119_abnormal_digestive_system0.91263468
102MP0000428_abnormal_craniofacial_morphol0.90487360
103MP0000778_abnormal_nervous_system0.90305015
104MP0001175_abnormal_lung_morphology0.89469591
105MP0004134_abnormal_chest_morphology0.88595429
106MP0000613_abnormal_salivary_gland0.88145120
107MP0004085_abnormal_heartbeat0.85036560
108MP0000579_abnormal_nail_morphology0.83390013
109MP0002653_abnormal_ependyma_morphology0.82775849
110MP0000751_myopathy0.82396861
111MP0005388_respiratory_system_phenotype0.81759843
112MP0002133_abnormal_respiratory_system0.81759843
113MP0000013_abnormal_adipose_tissue0.80928131
114MP0000647_abnormal_sebaceous_gland0.80857792
115MP0006054_spinal_hemorrhage0.80611998
116MP0005220_abnormal_exocrine_pancreas0.79502434
117MP0002092_abnormal_eye_morphology0.79034321
118MP0003943_abnormal_hepatobiliary_system0.78734701
119MP0003868_abnormal_feces_composition0.78026555
120MP0000762_abnormal_tongue_morphology0.77696454
121MP0002332_abnormal_exercise_endurance0.77534322
122MP0000537_abnormal_urethra_morphology0.77509559
123MP0004811_abnormal_neuron_physiology0.76897597
124MP0001664_abnormal_digestion0.76842003
125MP0006276_abnormal_autonomic_nervous0.76794574
126MP0002234_abnormal_pharynx_morphology0.76117351
127MP0003942_abnormal_urinary_system0.76102759
128MP0003011_delayed_dark_adaptation0.75755750
129MP0000955_abnormal_spinal_cord0.74806540
130MP0001324_abnormal_eye_pigmentation0.74005437
131MP0002109_abnormal_limb_morphology0.73737347
132MP0002932_abnormal_joint_morphology0.73700879
133MP0004084_abnormal_cardiac_muscle0.73104110
134MP0005083_abnormal_biliary_tract0.73092532
135MP0003755_abnormal_palate_morphology0.72734990
136MP0001849_ear_inflammation0.72342043
137MP0001614_abnormal_blood_vessel0.71742455
138MP0002249_abnormal_larynx_morphology0.71475166
139MP0002697_abnormal_eye_size0.71474292
140MP0001943_abnormal_respiration0.71196399
141MP0002128_abnormal_blood_circulation0.71109276
142MP0000462_abnormal_digestive_system0.71037924
143MP0002115_abnormal_skeleton_extremities0.70989472
144MP0001851_eye_inflammation0.70621942
145MP0000230_abnormal_systemic_arterial0.70384921
146MP0001501_abnormal_sleep_pattern0.70037545
147MP0003935_abnormal_craniofacial_develop0.69586202
148MP0000427_abnormal_hair_cycle0.69444639
149MP0005394_taste/olfaction_phenotype0.67594824
150MP0002135_abnormal_kidney_morphology0.67566003
151MP0003136_yellow_coat_color0.66053472
152MP0000049_abnormal_middle_ear0.65544793
153MP0002896_abnormal_bone_mineralization0.65405063
154MP0002925_abnormal_cardiovascular_devel0.65310575
155MP0000163_abnormal_cartilage_morphology0.64388484
156MP0005623_abnormal_meninges_morphology0.63052850
157MP0003879_abnormal_hair_cell0.62090304
158MP0002116_abnormal_craniofacial_bone0.61379810
159MP0002136_abnormal_kidney_physiology0.61041467
160MP0000681_abnormal_thyroid_gland0.60699734
161MP0005197_abnormal_uvea_morphology0.60285334
162MP0002127_abnormal_cardiovascular_syste0.59714247
163MP0000733_abnormal_muscle_development0.59109136

Predicted human phenotypes

RankGene SetZ-score
1Interstitial pulmonary disease (HP:0006530)6.14010253
2Febrile seizures (HP:0002373)5.59103323
3Glomerulonephritis (HP:0000099)5.16682969
4Epileptic encephalopathy (HP:0200134)5.00959091
5Central scotoma (HP:0000603)4.61322715
6Partial duplication of thumb phalanx (HP:0009944)4.59886291
7Abnormality of macular pigmentation (HP:0008002)4.55152680
8Partial duplication of the phalanx of hand (HP:0009999)4.46686482
9Nephritis (HP:0000123)4.46338178
10Severe visual impairment (HP:0001141)4.39040183
11Midline defect of the nose (HP:0004122)3.97229721
12Decreased central vision (HP:0007663)3.78204906
13Hyperkalemia (HP:0002153)3.75222757
14Absent/shortened dynein arms (HP:0200106)3.59748809
15Dynein arm defect of respiratory motile cilia (HP:0012255)3.59748809
16Hyperactive renin-angiotensin system (HP:0000841)3.55358054
17Recurrent corneal erosions (HP:0000495)3.51792911
18Abnormality of the parietal bone (HP:0002696)3.41078803
19Abnormal ciliary motility (HP:0012262)3.29469988
20Tubulointerstitial fibrosis (HP:0005576)3.19057051
21Conical tooth (HP:0000698)3.17587137
22Septo-optic dysplasia (HP:0100842)3.13328002
23Mixed hearing impairment (HP:0000410)3.12595318
24Abnormal respiratory motile cilium morphology (HP:0005938)3.11780362
25Abnormal respiratory epithelium morphology (HP:0012253)3.11780362
26Aplasia of the musculature (HP:0100854)3.02404788
27Stage 5 chronic kidney disease (HP:0003774)2.97136605
28Absence seizures (HP:0002121)2.96256556
29Scotoma (HP:0000575)2.95762103
30Respiratory distress (HP:0002098)2.93857272
31Progressive cerebellar ataxia (HP:0002073)2.91255955
32Abnormality of the nasal septum (HP:0000419)2.88816114
33Abnormal rod and cone electroretinograms (HP:0008323)2.88587828
34Corneal erosion (HP:0200020)2.86225179
35Aortic aneurysm (HP:0004942)2.85192043
36Hyperventilation (HP:0002883)2.84588244
37Mesomelia (HP:0003027)2.84319308
38Abnormal respiratory motile cilium physiology (HP:0012261)2.81186436
39Humeroradial synostosis (HP:0003041)2.80321790
40Synostosis involving the elbow (HP:0003938)2.80321790
41Nonprogressive disorder (HP:0003680)2.75770553
42Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.69036568
43Increased corneal curvature (HP:0100692)2.65050739
44Keratoconus (HP:0000563)2.65050739
45Vascular tortuosity (HP:0004948)2.64560922
46Bell-shaped thorax (HP:0001591)2.63600555
47Tubulointerstitial abnormality (HP:0001969)2.63527952
48Tachypnea (HP:0002789)2.60432303
49Chronic bronchitis (HP:0004469)2.58095690
50Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.58049220
51Abnormality of the dental pulp (HP:0006479)2.57461943
52Absent speech (HP:0001344)2.55333520
53Abnormality of molar (HP:0011077)2.54510495
54Abnormality of molar morphology (HP:0011070)2.54510495
55Broad metatarsal (HP:0001783)2.54142515
56Gait imbalance (HP:0002141)2.52056328
57Aortic dissection (HP:0002647)2.50990026
58Abnormality of the dental root (HP:0006486)2.49567227
59Taurodontia (HP:0000679)2.49567227
60Abnormality of permanent molar morphology (HP:0011071)2.49567227
61Decreased circulating renin level (HP:0003351)2.46878139
62Neoplasm of the heart (HP:0100544)2.46349012
63Rhinitis (HP:0012384)2.46329780
64Abnormality of the phalanges of the 2nd finger (HP:0009541)2.45245821
65Trigonocephaly (HP:0000243)2.45063195
66Medial flaring of the eyebrow (HP:0010747)2.44305977
67Duplication of thumb phalanx (HP:0009942)2.43986405
68Congenital primary aphakia (HP:0007707)2.41831611
69Chorioretinal atrophy (HP:0000533)2.41077961
70Premature rupture of membranes (HP:0001788)2.34623224
71Action tremor (HP:0002345)2.33901640
72Short 4th metacarpal (HP:0010044)2.31758800
73Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.31758800
74Corneal dystrophy (HP:0001131)2.29814066
75Focal motor seizures (HP:0011153)2.28634544
76Broad toe (HP:0001837)2.28271999
77Aplasia/Hypoplasia of the tongue (HP:0010295)2.26737719
78Hypoplasia of the iris (HP:0007676)2.26450508
79Coronal craniosynostosis (HP:0004440)2.26327649
80Arterial tortuosity (HP:0005116)2.26212430
81Preaxial foot polydactyly (HP:0001841)2.25410131
82Severe Myopia (HP:0011003)2.23728080
83Dialeptic seizures (HP:0011146)2.23008724
84Nephrogenic diabetes insipidus (HP:0009806)2.20822906
85Vaginal atresia (HP:0000148)2.20386288
86Abnormality of the sella turcica (HP:0002679)2.20112251
87Cutaneous finger syndactyly (HP:0010554)2.19892010
88Generalized tonic-clonic seizures (HP:0002069)2.19011467
89Hyperextensible skin (HP:0000974)2.15578082
90Hyperaldosteronism (HP:0000859)2.15346129
91Protrusio acetabuli (HP:0003179)2.15326836
92Prolonged QT interval (HP:0001657)2.12910356
93Genital tract atresia (HP:0001827)2.12758287
94Bony spicule pigmentary retinopathy (HP:0007737)2.12352587
95Nasolacrimal duct obstruction (HP:0000579)2.11987179
96Narrow nasal bridge (HP:0000446)2.10942726
97Abnormality of the middle phalanges of the toes (HP:0010183)2.10726035
98Short phalanx of the thumb (HP:0009660)2.10114115
99Aqueductal stenosis (HP:0002410)2.08009867
100Blue irides (HP:0000635)2.07581456
101Occipital encephalocele (HP:0002085)2.07247413
102Hypoplasia of the fovea (HP:0007750)2.07182769
103Aplasia/Hypoplasia of the fovea (HP:0008060)2.07182769
104Camptodactyly of toe (HP:0001836)2.06005959
105Drooling (HP:0002307)2.05324197
106Excessive salivation (HP:0003781)2.05324197
107True hermaphroditism (HP:0010459)2.05032240
108Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.01936311
109Congenital sensorineural hearing impairment (HP:0008527)2.01624399
110Congenital stationary night blindness (HP:0007642)12.0066415
111Abnormality of the nasolacrimal system (HP:0000614)1.99465582
112Aplasia/Hypoplasia of the lens (HP:0008063)1.99410413
113Aplasia involving bones of the extremities (HP:0009825)1.98488615
114Aplasia involving bones of the upper limbs (HP:0009823)1.98488615
115Aplasia of the phalanges of the hand (HP:0009802)1.98488615
116Absent septum pellucidum (HP:0001331)1.98191937
117Anophthalmia (HP:0000528)1.97766187
118Soft skin (HP:0000977)1.97707556
119Turricephaly (HP:0000262)1.97464344
120Abnormality of the ischium (HP:0003174)1.97436185
121Xerostomia (HP:0000217)1.97156910
122Shallow orbits (HP:0000586)1.96760467
123Congenital glaucoma (HP:0001087)1.96368494
124Aplasia cutis congenita (HP:0001057)1.96085487
125Neonatal short-limb short stature (HP:0008921)1.95618429
126Hypoventilation (HP:0002791)1.95494194
127Cupped ear (HP:0000378)1.94041534
128Hyponatremia (HP:0002902)1.93567845
129Abnormal gallbladder physiology (HP:0012438)1.93089346
130Cholecystitis (HP:0001082)1.93089346
131Depressed nasal tip (HP:0000437)1.92000424
132Renal salt wasting (HP:0000127)1.91717449
133Bladder diverticulum (HP:0000015)1.91148430
134Metaphyseal dysplasia (HP:0100255)1.91045640
135Anteriorly placed anus (HP:0001545)1.90883869
136Long toe (HP:0010511)1.90323387
137Alacrima (HP:0000522)1.87819001
138Abnormality of abdominal situs (HP:0011620)1.87532722
139Abdominal situs inversus (HP:0003363)1.87532722
140Widely spaced teeth (HP:0000687)1.86406587
141Abnormality of the lacrimal duct (HP:0011481)1.85524642
142Fibular aplasia (HP:0002990)1.85420485
143Bicornuate uterus (HP:0000813)1.83701471
144Anterior segment dysgenesis (HP:0007700)1.83619762
145Abnormality of incisor morphology (HP:0011063)1.83323499
146Hypoplasia of the ulna (HP:0003022)1.83231125
147Tubulointerstitial nephritis (HP:0001970)1.82951130
148Tubular atrophy (HP:0000092)1.82658372
149Facial shape deformation (HP:0011334)1.82254269
150Potter facies (HP:0002009)1.82254269
151Vitreoretinal degeneration (HP:0000655)1.81781906
152Genetic anticipation (HP:0003743)1.81741709
153Poor coordination (HP:0002370)1.80895223
154Abnormality of the musculature of the hand (HP:0001421)1.80749818
155Cone-rod dystrophy (HP:0000548)1.78688581
156Absent phalangeal crease (HP:0006109)1.78298078
157Truncal ataxia (HP:0002078)1.77697904
158Narrow palate (HP:0000189)1.77557933
159Abnormality of the septum pellucidum (HP:0007375)1.77243220
160Pulmonary artery stenosis (HP:0004415)1.77238952
161Cutaneous syndactyly (HP:0012725)1.77080641
162Polar cataract (HP:0010696)1.76864188
163Abnormality of the diencephalon (HP:0010662)1.76505207
164Abnormality of chloride homeostasis (HP:0011422)1.75775443
165Chronic hepatic failure (HP:0100626)1.75300921
166Wide anterior fontanel (HP:0000260)1.73875629
167Short metatarsal (HP:0010743)1.73387117
168Aplasia/Hypoplasia of metatarsal bones (HP:0001964)1.73254241
169Abnormality of the distal phalanx of the thumb (HP:0009617)1.71251377
170Decreased lacrimation (HP:0000633)1.68525303
171Abnormality of the incisor (HP:0000676)1.68186098
172Growth hormone deficiency (HP:0000824)1.65046787
173Broad hallux (HP:0010055)1.64605654
174EEG with generalized epileptiform discharges (HP:0011198)1.63176448
175Abnormality of salivation (HP:0100755)1.62245211
176Short foot (HP:0001773)1.60524771
177Thickened helices (HP:0000391)1.60016318
178Abnormality of the proximal phalanges of the hand (HP:0009834)1.59531832
179Pancreatic fibrosis (HP:0100732)1.59518682

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE14.76783064
2MAPK154.31457798
3CASK3.31941810
4EPHA33.14689967
5CAMK1D2.94223950
6CAMK1G2.81774436
7TGFBR22.59139883
8INSRR2.36164917
9FGFR22.33788022
10EPHB22.13876366
11PBK2.11207354
12PRPF4B2.07144336
13MAP2K71.86996927
14RIPK11.86862243
15EPHB11.84050751
16EPHA41.83070513
17MOS1.77570864
18AKT31.72569725
19CDK31.69767465
20TESK11.65204722
21ERBB31.63256862
22GRK11.59212197
23TNIK1.54279746
24MAP3K41.50826812
25NLK1.46669096
26NTRK11.46165942
27MARK11.44959977
28IRAK11.43486222
29YES11.42000265
30NME11.40028405
31DAPK21.39964907
32LATS11.37853035
33MYLK1.37337065
34TRPM71.36334212
35PDGFRA1.35255569
36FRK1.32826288
37DYRK1A1.32506336
38BRD41.31883600
39GRK51.30274495
40PRKCE1.26915458
41LATS21.26564586
42PAK61.25772380
43MAP3K131.25292812
44STK381.23888570
45OBSCN1.23113569
46LRRK21.22515981
47MET1.21268610
48SGK21.20637144
49NTRK31.20548100
50TAOK21.20187815
51MAP3K61.17202060
52DYRK1B1.17144329
53ADRBK21.14271219
54CAMK11.11733258
55BMX1.11573730
56SGK4941.08876341
57SGK2231.08876341
58GRK71.08498500
59PHKG11.05865534
60PHKG21.05865534
61CLK11.04211297
62PDGFRB1.03584747
63MAP3K71.03263063
64NEK91.02347346
65MINK11.01505791
66PINK10.97026846
67FER0.96831805
68CAMK2D0.92704771
69STK38L0.92085038
70FGFR40.92004078
71TEC0.91834897
72RET0.90425073
73FGFR10.86360945
74FGFR30.85764853
75RPS6KA20.85021007
76LIMK10.83269233
77PKN20.81301622
78SGK30.80948314
79PLK20.80300659
80EIF2AK20.79652375
81PLK40.78337244
82BMPR1B0.78021977
83CAMK2B0.77633712
84MAPK70.77488377
85PIK3CA0.76749986
86PKN10.76329553
87TGFBR10.76287277
88MAPK130.74403381
89NTRK20.72651561
90STK390.71734618
91MAP4K20.71014500
92PRKCZ0.70954608
93DDR20.68978913
94IRAK20.68391247
95CAMK40.68245734
96ADRBK10.67367377
97PRKD10.66380919
98MAP3K90.66031357
99PAK20.66000485
100ROCK10.64921113
101PRKG10.64513619
102LMTK20.63941613
103WNK30.62506892
104SGK10.62109163
105ERBB20.62011706
106PRKCG0.61405329
107MST1R0.61188410
108PDPK10.60731768
109RPS6KA60.60593123
110HIPK20.60270209
111CAMK2A0.59999000
112CDK50.59403950
113RPS6KC10.56024080
114RPS6KL10.56024080
115PRKAA10.55693555
116PRKAA20.54288354
117PNCK0.52169286
118PAK30.51872805
119AKT20.51104862
120GSK3B0.48910084
121ROCK20.48774580
122FES0.48669085
123TNK20.48661819
124KIT0.48555810
125STK240.48372720
126MAPK100.47624200
127CDK80.47258332
128PRKCA0.47019618
129STK110.45460640
130STK30.45345175
131PDK20.44840613
132IGF1R0.44334777
133MAP3K120.44180081
134MAPKAPK50.42468908
135PIK3CG0.42116845
136MKNK10.41961566
137PRKCB0.41497512
138PRKCH0.41068481
139DMPK0.40849834
140MARK20.40610365
141PRKACA0.40552770
142INSR0.40116904
143MAPK40.40087587
144ZAK0.39953670
145FLT30.39536010
146PRKD20.37695953
147MAP2K40.36943093
148RPS6KA30.36935286
149GSK3A0.36810443
150MAPK80.36740666
151CDK90.36338093
152BCR0.35978573
153CHUK0.35252591
154NUAK10.34893019
155NEK10.34835274
156IRAK40.34516507
157CDC42BPA0.34326684
158SRC0.34134268

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.51768909
2Nitrogen metabolism_Homo sapiens_hsa009103.42649223
3GABAergic synapse_Homo sapiens_hsa047273.34450163
4Morphine addiction_Homo sapiens_hsa050323.06934438
5Synaptic vesicle cycle_Homo sapiens_hsa047212.87561772
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.67135161
7Circadian entrainment_Homo sapiens_hsa047132.40637435
8Phototransduction_Homo sapiens_hsa047442.15051610
9Circadian rhythm_Homo sapiens_hsa047102.11982734
10Insulin secretion_Homo sapiens_hsa049112.04372165
11Olfactory transduction_Homo sapiens_hsa047402.00538893
12Salivary secretion_Homo sapiens_hsa049701.93868930
13Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.93604768
14Renin secretion_Homo sapiens_hsa049241.89770741
15Glutamatergic synapse_Homo sapiens_hsa047241.85925553
16Taste transduction_Homo sapiens_hsa047421.84119105
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.78149584
18Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.77422596
19Cholinergic synapse_Homo sapiens_hsa047251.73963252
20Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.67327404
21Glycosaminoglycan degradation_Homo sapiens_hsa005311.66533772
22Serotonergic synapse_Homo sapiens_hsa047261.61783798
23Dilated cardiomyopathy_Homo sapiens_hsa054141.59467431
24Tryptophan metabolism_Homo sapiens_hsa003801.58075266
25Aldosterone synthesis and secretion_Homo sapiens_hsa049251.47708038
26Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.46427306
27Histidine metabolism_Homo sapiens_hsa003401.45009622
28Fructose and mannose metabolism_Homo sapiens_hsa000511.42552962
29Dopaminergic synapse_Homo sapiens_hsa047281.41562404
30Oxytocin signaling pathway_Homo sapiens_hsa049211.40763634
31Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.39621782
32Amoebiasis_Homo sapiens_hsa051461.38682592
33Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.36415447
34Basal cell carcinoma_Homo sapiens_hsa052171.32287585
35Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.30968756
36Tight junction_Homo sapiens_hsa045301.30445970
37ECM-receptor interaction_Homo sapiens_hsa045121.28308461
38Complement and coagulation cascades_Homo sapiens_hsa046101.26160988
39Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.23600317
40Hedgehog signaling pathway_Homo sapiens_hsa043401.22560649
41Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.20111964
42cGMP-PKG signaling pathway_Homo sapiens_hsa040221.18446020
43Mineral absorption_Homo sapiens_hsa049781.18426686
44Calcium signaling pathway_Homo sapiens_hsa040201.16808583
45Small cell lung cancer_Homo sapiens_hsa052221.15310752
46Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.14537552
47Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.11834971
48Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.08242574
49cAMP signaling pathway_Homo sapiens_hsa040241.07453422
50Vascular smooth muscle contraction_Homo sapiens_hsa042701.06735361
51Central carbon metabolism in cancer_Homo sapiens_hsa052301.02795217
52Collecting duct acid secretion_Homo sapiens_hsa049661.01212362
53Cocaine addiction_Homo sapiens_hsa050300.99885626
54Melanoma_Homo sapiens_hsa052180.98990839
55Long-term depression_Homo sapiens_hsa047300.98628193
56Gap junction_Homo sapiens_hsa045400.98551522
57Bile secretion_Homo sapiens_hsa049760.96765161
58Amphetamine addiction_Homo sapiens_hsa050310.96717956
59Gastric acid secretion_Homo sapiens_hsa049710.95609798
60Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.92439564
61Axon guidance_Homo sapiens_hsa043600.90928316
62beta-Alanine metabolism_Homo sapiens_hsa004100.88960788
63Wnt signaling pathway_Homo sapiens_hsa043100.88664040
64Rheumatoid arthritis_Homo sapiens_hsa053230.88302438
65Thyroid hormone signaling pathway_Homo sapiens_hsa049190.88167702
66Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.87989669
67Fatty acid degradation_Homo sapiens_hsa000710.87386010
68Proteoglycans in cancer_Homo sapiens_hsa052050.87320679
69Primary bile acid biosynthesis_Homo sapiens_hsa001200.87283775
70Cardiac muscle contraction_Homo sapiens_hsa042600.84260504
71Ovarian steroidogenesis_Homo sapiens_hsa049130.83622994
72Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.83132121
73MAPK signaling pathway_Homo sapiens_hsa040100.79875234
74Adherens junction_Homo sapiens_hsa045200.78186344
75Pertussis_Homo sapiens_hsa051330.77489817
76Type II diabetes mellitus_Homo sapiens_hsa049300.76298859
77Regulation of actin cytoskeleton_Homo sapiens_hsa048100.75220627
78Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.75119139
79Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.72746797
80Sphingolipid metabolism_Homo sapiens_hsa006000.72518508
81Galactose metabolism_Homo sapiens_hsa000520.72277614
82Pentose phosphate pathway_Homo sapiens_hsa000300.71836411
83Lysosome_Homo sapiens_hsa041420.71449134
84Linoleic acid metabolism_Homo sapiens_hsa005910.70963976
85Arachidonic acid metabolism_Homo sapiens_hsa005900.69631871
86Chemical carcinogenesis_Homo sapiens_hsa052040.69341147
87ErbB signaling pathway_Homo sapiens_hsa040120.68493327
88Long-term potentiation_Homo sapiens_hsa047200.68466435
89Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.68037164
90Ras signaling pathway_Homo sapiens_hsa040140.67905940
91SNARE interactions in vesicular transport_Homo sapiens_hsa041300.67682838
92GnRH signaling pathway_Homo sapiens_hsa049120.67231335
93Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.66518682
94Rap1 signaling pathway_Homo sapiens_hsa040150.66054265
95Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.65985641
96Hippo signaling pathway_Homo sapiens_hsa043900.65296010
97Melanogenesis_Homo sapiens_hsa049160.65167942
98alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.64262991
99Notch signaling pathway_Homo sapiens_hsa043300.61589512
100PI3K-Akt signaling pathway_Homo sapiens_hsa041510.61497853
101Phagosome_Homo sapiens_hsa041450.59848670
102TGF-beta signaling pathway_Homo sapiens_hsa043500.58374981
103Pathways in cancer_Homo sapiens_hsa052000.57720214
104Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.57074496
105Malaria_Homo sapiens_hsa051440.56875013
106Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.56195893
107HIF-1 signaling pathway_Homo sapiens_hsa040660.55887992
108Vibrio cholerae infection_Homo sapiens_hsa051100.53566578
109Phenylalanine metabolism_Homo sapiens_hsa003600.53137863
110Phosphatidylinositol signaling system_Homo sapiens_hsa040700.52474198
111Ether lipid metabolism_Homo sapiens_hsa005650.51880546
112Renin-angiotensin system_Homo sapiens_hsa046140.51778069
113Retinol metabolism_Homo sapiens_hsa008300.50454458
114Endometrial cancer_Homo sapiens_hsa052130.50325405
115Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.49973282
116Pancreatic secretion_Homo sapiens_hsa049720.49907018
117Choline metabolism in cancer_Homo sapiens_hsa052310.49183358
118Focal adhesion_Homo sapiens_hsa045100.49136177
119Propanoate metabolism_Homo sapiens_hsa006400.48958023
120Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.48756302
121Colorectal cancer_Homo sapiens_hsa052100.48691526
122African trypanosomiasis_Homo sapiens_hsa051430.47953279
123Arginine and proline metabolism_Homo sapiens_hsa003300.47863186
124Glioma_Homo sapiens_hsa052140.45173250
125Tyrosine metabolism_Homo sapiens_hsa003500.44819130
126Inositol phosphate metabolism_Homo sapiens_hsa005620.43783574
127AMPK signaling pathway_Homo sapiens_hsa041520.43435790
128Butanoate metabolism_Homo sapiens_hsa006500.41662328
129Steroid hormone biosynthesis_Homo sapiens_hsa001400.41585114
130Lysine degradation_Homo sapiens_hsa003100.40752724
131Phospholipase D signaling pathway_Homo sapiens_hsa040720.40716311
132Thyroid hormone synthesis_Homo sapiens_hsa049180.39822511
133Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.37535371
134Protein digestion and absorption_Homo sapiens_hsa049740.36322096
135Alcoholism_Homo sapiens_hsa050340.34831543
136Dorso-ventral axis formation_Homo sapiens_hsa043200.34631314
137ABC transporters_Homo sapiens_hsa020100.33992978
138Estrogen signaling pathway_Homo sapiens_hsa049150.33609517
139AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.33292747
140Carbohydrate digestion and absorption_Homo sapiens_hsa049730.33076744
141Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.30190308
142Renal cell carcinoma_Homo sapiens_hsa052110.30082892
143mTOR signaling pathway_Homo sapiens_hsa041500.30035295

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