

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 6.59553674 |
| 2 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 6.59553674 |
| 3 | substrate-independent telencephalic tangential migration (GO:0021826) | 5.54505364 |
| 4 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 5.54505364 |
| 5 | resolution of meiotic recombination intermediates (GO:0000712) | 5.38216623 |
| 6 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 5.18877843 |
| 7 | axon extension involved in axon guidance (GO:0048846) | 5.18877843 |
| 8 | protein polyglutamylation (GO:0018095) | 4.95251894 |
| 9 | positive regulation of male gonad development (GO:2000020) | 4.91921770 |
| 10 | axonal fasciculation (GO:0007413) | 4.87062473 |
| 11 | retinal ganglion cell axon guidance (GO:0031290) | 4.85749867 |
| 12 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.63033836 |
| 13 | respiratory chain complex IV assembly (GO:0008535) | 4.54310945 |
| 14 | somite development (GO:0061053) | 4.39107566 |
| 15 | pyrimidine nucleobase catabolic process (GO:0006208) | 4.29985167 |
| 16 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 4.29004708 |
| 17 | sequestering of actin monomers (GO:0042989) | 4.20913556 |
| 18 | response to pheromone (GO:0019236) | 4.15386168 |
| 19 | cardiac left ventricle morphogenesis (GO:0003214) | 4.08250687 |
| 20 | meiotic chromosome segregation (GO:0045132) | 4.06258758 |
| 21 | peripheral nervous system neuron development (GO:0048935) | 3.93723630 |
| 22 | positive regulation of mitochondrial membrane permeability (GO:0035794) | 3.93453302 |
| 23 | DNA damage response, detection of DNA damage (GO:0042769) | 3.89735868 |
| 24 | platelet dense granule organization (GO:0060155) | 3.88598285 |
| 25 | viral transcription (GO:0019083) | 3.85117888 |
| 26 | intraciliary transport (GO:0042073) | 3.84292644 |
| 27 | translational termination (GO:0006415) | 3.79069562 |
| 28 | regulation of male gonad development (GO:2000018) | 3.74470633 |
| 29 | epithelial cilium movement (GO:0003351) | 3.74187128 |
| 30 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.73539501 |
| 31 | positive regulation of mitochondrial fission (GO:0090141) | 3.71519174 |
| 32 | behavioral response to nicotine (GO:0035095) | 3.57676632 |
| 33 | nucleobase catabolic process (GO:0046113) | 3.53891784 |
| 34 | positive regulation of vesicle fusion (GO:0031340) | 3.53269861 |
| 35 | ribosomal small subunit assembly (GO:0000028) | 3.52443685 |
| 36 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 3.51013215 |
| 37 | cytochrome complex assembly (GO:0017004) | 3.48091335 |
| 38 | cotranslational protein targeting to membrane (GO:0006613) | 3.39448045 |
| 39 | neurofilament cytoskeleton organization (GO:0060052) | 3.38895236 |
| 40 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.37700304 |
| 41 | protein targeting to ER (GO:0045047) | 3.32384878 |
| 42 | neuron fate determination (GO:0048664) | 3.24006590 |
| 43 | neuron recognition (GO:0008038) | 3.23097025 |
| 44 | aldehyde catabolic process (GO:0046185) | 3.22326478 |
| 45 | nonmotile primary cilium assembly (GO:0035058) | 3.19819878 |
| 46 | regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902108) | 3.16059357 |
| 47 | protein complex biogenesis (GO:0070271) | 3.15378792 |
| 48 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.14762437 |
| 49 | positive regulation of protein homooligomerization (GO:0032464) | 3.12845611 |
| 50 | protein localization to endoplasmic reticulum (GO:0070972) | 3.11961648 |
| 51 | response to folic acid (GO:0051593) | 3.11759346 |
| 52 | cilium organization (GO:0044782) | 3.11238846 |
| 53 | glycerol metabolic process (GO:0006071) | 3.10262530 |
| 54 | cilium assembly (GO:0042384) | 3.09438311 |
| 55 | regulation of penile erection (GO:0060405) | 3.09042632 |
| 56 | translational elongation (GO:0006414) | 3.08185525 |
| 57 | neuronal stem cell maintenance (GO:0097150) | 3.06034244 |
| 58 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 3.05201262 |
| 59 | proteasome assembly (GO:0043248) | 3.02231444 |
| 60 | anterograde synaptic vesicle transport (GO:0048490) | 3.01150764 |
| 61 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.00803232 |
| 62 | kinetochore organization (GO:0051383) | 2.99239767 |
| 63 | chaperone-mediated protein transport (GO:0072321) | 2.98874329 |
| 64 | negative regulation of mast cell activation (GO:0033004) | 2.98195693 |
| 65 | forebrain neuron differentiation (GO:0021879) | 2.94706669 |
| 66 | spinal cord association neuron differentiation (GO:0021527) | 2.93160704 |
| 67 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.91462348 |
| 68 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.91462348 |
| 69 | NADH dehydrogenase complex assembly (GO:0010257) | 2.91462348 |
| 70 | cellular protein complex disassembly (GO:0043624) | 2.86989452 |
| 71 | negative regulation of neurotransmitter transport (GO:0051589) | 2.85946877 |
| 72 | translesion synthesis (GO:0019985) | 2.82434584 |
| 73 | centriole replication (GO:0007099) | 2.80154454 |
| 74 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.78583682 |
| 75 | myoblast migration (GO:0051451) | 2.78419207 |
| 76 | ribosomal small subunit biogenesis (GO:0042274) | 2.77095463 |
| 77 | rRNA catabolic process (GO:0016075) | 2.76258498 |
| 78 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.75296499 |
| 79 | negative regulation of axon guidance (GO:1902668) | 2.74422447 |
| 80 | regulation of synapse structural plasticity (GO:0051823) | 2.74203845 |
| 81 | cilium movement (GO:0003341) | 2.74078329 |
| 82 | positive regulation of gastrulation (GO:2000543) | 2.72697330 |
| 83 | postsynaptic membrane organization (GO:0001941) | 2.71078086 |
| 84 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.70992500 |
| 85 | diacylglycerol metabolic process (GO:0046339) | 2.68495227 |
| 86 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 2.68050580 |
| 87 | retinal rod cell development (GO:0046548) | 2.67905959 |
| 88 | regulation of glycogen (starch) synthase activity (GO:2000465) | 2.67613422 |
| 89 | phasic smooth muscle contraction (GO:0014821) | 2.66757067 |
| 90 | protein K48-linked ubiquitination (GO:0070936) | 2.66240986 |
| 91 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 2.65773931 |
| 92 | anterograde axon cargo transport (GO:0008089) | 2.62410606 |
| 93 | regulation of mitochondrial fission (GO:0090140) | 2.61048621 |
| 94 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.59733040 |
| 95 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.59733040 |
| 96 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.59341715 |
| 97 | negative regulation of amino acid transport (GO:0051956) | 2.58256877 |
| 98 | DNA double-strand break processing (GO:0000729) | 2.57436971 |
| 99 | photoreceptor cell development (GO:0042461) | 2.57126891 |
| 100 | synapse assembly (GO:0007416) | 2.56089834 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.40541960 |
| 2 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.75519074 |
| 3 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.13652304 |
| 4 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.00168642 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.85968133 |
| 6 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.64029993 |
| 7 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.61331794 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.59633604 |
| 9 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.57393460 |
| 10 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.54557443 |
| 11 | EWS_26573619_Chip-Seq_HEK293_Human | 2.41820325 |
| 12 | RNF2_27304074_Chip-Seq_NSC_Mouse | 2.40791240 |
| 13 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.38106517 |
| 14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.35327915 |
| 15 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.34307323 |
| 16 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.33378099 |
| 17 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.31271142 |
| 18 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.26563798 |
| 19 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.20331610 |
| 20 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.07872474 |
| 21 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.01047414 |
| 22 | FUS_26573619_Chip-Seq_HEK293_Human | 1.97020560 |
| 23 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.95926038 |
| 24 | P300_19829295_ChIP-Seq_ESCs_Human | 1.93403505 |
| 25 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.84795042 |
| 26 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.81106260 |
| 27 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.80822827 |
| 28 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.79599671 |
| 29 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.78865257 |
| 30 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.76549906 |
| 31 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.73071565 |
| 32 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.72672705 |
| 33 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.68153054 |
| 34 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.67350484 |
| 35 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.64834590 |
| 36 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.63539776 |
| 37 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.59778496 |
| 38 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.56767684 |
| 39 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.54075479 |
| 40 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.52649743 |
| 41 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.44719829 |
| 42 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.40193427 |
| 43 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.39636919 |
| 44 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.38540298 |
| 45 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.37620843 |
| 46 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.36767826 |
| 47 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.35881946 |
| 48 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.35480400 |
| 49 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.34654825 |
| 50 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.34550709 |
| 51 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.33889457 |
| 52 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.33510397 |
| 53 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.33384706 |
| 54 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.33311251 |
| 55 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.33230056 |
| 56 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.33035214 |
| 57 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.32096154 |
| 58 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.31952293 |
| 59 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.30326075 |
| 60 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.29387194 |
| 61 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.24505425 |
| 62 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.24393385 |
| 63 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.24123169 |
| 64 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.23802451 |
| 65 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.23596049 |
| 66 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.22925610 |
| 67 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.21227423 |
| 68 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.19180791 |
| 69 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.19144086 |
| 70 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.19018132 |
| 71 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.19018132 |
| 72 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.17439501 |
| 73 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.16643365 |
| 74 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.14849211 |
| 75 | STAT3_23295773_ChIP-Seq_U87_Human | 1.14320752 |
| 76 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.14098954 |
| 77 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.13896879 |
| 78 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.10821411 |
| 79 | AR_25329375_ChIP-Seq_VCAP_Human | 1.10525539 |
| 80 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.10498778 |
| 81 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.09444088 |
| 82 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.08119392 |
| 83 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.08055464 |
| 84 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.07981182 |
| 85 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.07784869 |
| 86 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.04495646 |
| 87 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.01281565 |
| 88 | JUN_21703547_ChIP-Seq_K562_Human | 1.01219848 |
| 89 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.99962809 |
| 90 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.99568897 |
| 91 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.99473332 |
| 92 | TCF4_23295773_ChIP-Seq_U87_Human | 0.99167200 |
| 93 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.99114366 |
| 94 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.98784519 |
| 95 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.97828375 |
| 96 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.94702410 |
| 97 | AR_20517297_ChIP-Seq_VCAP_Human | 0.91659998 |
| 98 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.91212337 |
| 99 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.90666344 |
| 100 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.90613837 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003880_abnormal_central_pattern | 4.84413668 |
| 2 | MP0003136_yellow_coat_color | 4.47210957 |
| 3 | MP0003123_paternal_imprinting | 3.93484844 |
| 4 | MP0006276_abnormal_autonomic_nervous | 3.82821317 |
| 5 | MP0003122_maternal_imprinting | 3.81431677 |
| 6 | MP0005171_absent_coat_pigmentation | 3.81173923 |
| 7 | MP0003121_genomic_imprinting | 3.77343208 |
| 8 | MP0002653_abnormal_ependyma_morphology | 3.63564165 |
| 9 | MP0002163_abnormal_gland_morphology | 3.38867388 |
| 10 | MP0005423_abnormal_somatic_nervous | 3.34462731 |
| 11 | MP0003787_abnormal_imprinting | 2.60520123 |
| 12 | MP0001348_abnormal_lacrimal_gland | 2.26413544 |
| 13 | MP0004147_increased_porphyrin_level | 2.23141986 |
| 14 | MP0000569_abnormal_digit_pigmentation | 2.22056975 |
| 15 | MP0005379_endocrine/exocrine_gland_phen | 2.16678311 |
| 16 | MP0006292_abnormal_olfactory_placode | 2.04547072 |
| 17 | MP0000778_abnormal_nervous_system | 2.00707215 |
| 18 | MP0006054_spinal_hemorrhage | 2.00165784 |
| 19 | MP0001984_abnormal_olfaction | 1.91677891 |
| 20 | MP0002254_reproductive_system_inflammat | 1.90849848 |
| 21 | MP0004142_abnormal_muscle_tone | 1.88629061 |
| 22 | MP0002638_abnormal_pupillary_reflex | 1.71768330 |
| 23 | MP0003646_muscle_fatigue | 1.68559428 |
| 24 | MP0004133_heterotaxia | 1.63989484 |
| 25 | MP0002876_abnormal_thyroid_physiology | 1.62567812 |
| 26 | MP0008058_abnormal_DNA_repair | 1.59961188 |
| 27 | MP0001346_abnormal_lacrimal_gland | 1.59682171 |
| 28 | MP0005248_abnormal_Harderian_gland | 1.48169725 |
| 29 | MP0002184_abnormal_innervation | 1.47114071 |
| 30 | MP0000955_abnormal_spinal_cord | 1.35995132 |
| 31 | MP0003011_delayed_dark_adaptation | 1.29932827 |
| 32 | MP0004145_abnormal_muscle_electrophysio | 1.28812185 |
| 33 | MP0002751_abnormal_autonomic_nervous | 1.25901027 |
| 34 | MP0005551_abnormal_eye_electrophysiolog | 1.25046144 |
| 35 | MP0001293_anophthalmia | 1.23705232 |
| 36 | MP0001529_abnormal_vocalization | 1.22863791 |
| 37 | MP0005645_abnormal_hypothalamus_physiol | 1.21637299 |
| 38 | MP0002095_abnormal_skin_pigmentation | 1.20271993 |
| 39 | MP0002928_abnormal_bile_duct | 1.19484143 |
| 40 | MP0002938_white_spotting | 1.19091236 |
| 41 | MP0002752_abnormal_somatic_nervous | 1.17382860 |
| 42 | MP0001286_abnormal_eye_development | 1.15292843 |
| 43 | MP0000013_abnormal_adipose_tissue | 1.13091525 |
| 44 | MP0005253_abnormal_eye_physiology | 1.12396433 |
| 45 | MP0001986_abnormal_taste_sensitivity | 1.12060294 |
| 46 | MP0005085_abnormal_gallbladder_physiolo | 1.11381861 |
| 47 | MP0005167_abnormal_blood-brain_barrier | 1.09459336 |
| 48 | MP0000647_abnormal_sebaceous_gland | 1.07615520 |
| 49 | MP0003937_abnormal_limbs/digits/tail_de | 1.07428732 |
| 50 | MP0005646_abnormal_pituitary_gland | 1.07053282 |
| 51 | MP0002736_abnormal_nociception_after | 1.05792116 |
| 52 | MP0010030_abnormal_orbit_morphology | 1.05578435 |
| 53 | MP0002557_abnormal_social/conspecific_i | 1.04182889 |
| 54 | MP0004859_abnormal_synaptic_plasticity | 1.01863352 |
| 55 | MP0003186_abnormal_redox_activity | 0.99780124 |
| 56 | MP0005195_abnormal_posterior_eye | 0.95253905 |
| 57 | MP0002233_abnormal_nose_morphology | 0.94734755 |
| 58 | MP0000049_abnormal_middle_ear | 0.94719039 |
| 59 | MP0002272_abnormal_nervous_system | 0.93292271 |
| 60 | MP0009046_muscle_twitch | 0.90148548 |
| 61 | MP0004484_altered_response_of | 0.87093598 |
| 62 | MP0005084_abnormal_gallbladder_morpholo | 0.85795007 |
| 63 | MP0005174_abnormal_tail_pigmentation | 0.84479582 |
| 64 | MP0002063_abnormal_learning/memory/cond | 0.84479544 |
| 65 | MP0002837_dystrophic_cardiac_calcinosis | 0.83998244 |
| 66 | MP0008877_abnormal_DNA_methylation | 0.83779723 |
| 67 | MP0001324_abnormal_eye_pigmentation | 0.83360249 |
| 68 | MP0003635_abnormal_synaptic_transmissio | 0.82865120 |
| 69 | MP0001970_abnormal_pain_threshold | 0.82666556 |
| 70 | MP0002882_abnormal_neuron_morphology | 0.81818338 |
| 71 | MP0009745_abnormal_behavioral_response | 0.79895545 |
| 72 | MP0006072_abnormal_retinal_apoptosis | 0.78155990 |
| 73 | MP0001963_abnormal_hearing_physiology | 0.77946224 |
| 74 | MP0002067_abnormal_sensory_capabilities | 0.76972937 |
| 75 | MP0001919_abnormal_reproductive_system | 0.76473407 |
| 76 | MP0004858_abnormal_nervous_system | 0.75950724 |
| 77 | MP0000026_abnormal_inner_ear | 0.75483071 |
| 78 | MP0005499_abnormal_olfactory_system | 0.72771023 |
| 79 | MP0005394_taste/olfaction_phenotype | 0.72771023 |
| 80 | MP0002152_abnormal_brain_morphology | 0.72283805 |
| 81 | MP0001119_abnormal_female_reproductive | 0.70553617 |
| 82 | MP0004270_analgesia | 0.69716393 |
| 83 | MP0001968_abnormal_touch/_nociception | 0.68190625 |
| 84 | MP0003755_abnormal_palate_morphology | 0.67605373 |
| 85 | MP0003936_abnormal_reproductive_system | 0.67002204 |
| 86 | MP0001270_distended_abdomen | 0.66671616 |
| 87 | MP0004811_abnormal_neuron_physiology | 0.66194329 |
| 88 | MP0002210_abnormal_sex_determination | 0.65863270 |
| 89 | MP0008932_abnormal_embryonic_tissue | 0.63615108 |
| 90 | MP0000653_abnormal_sex_gland | 0.63189521 |
| 91 | MP0003567_abnormal_fetal_cardiomyocyte | 0.62203828 |
| 92 | MP0009250_abnormal_appendicular_skeleto | 0.62007733 |
| 93 | MP0002734_abnormal_mechanical_nocicepti | 0.61842868 |
| 94 | MP0005377_hearing/vestibular/ear_phenot | 0.61593754 |
| 95 | MP0003878_abnormal_ear_physiology | 0.61593754 |
| 96 | MP0001879_abnormal_lymphatic_vessel | 0.61333407 |
| 97 | MP0005391_vision/eye_phenotype | 0.60058498 |
| 98 | MP0001486_abnormal_startle_reflex | 0.59506575 |
| 99 | MP0002116_abnormal_craniofacial_bone | 0.58524621 |
| 100 | MP0008875_abnormal_xenobiotic_pharmacok | 0.58497217 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | True hermaphroditism (HP:0010459) | 6.05602180 |
| 2 | Pancreatic cysts (HP:0001737) | 4.17988776 |
| 3 | Metaphyseal dysplasia (HP:0100255) | 4.02555389 |
| 4 | Molar tooth sign on MRI (HP:0002419) | 4.01575062 |
| 5 | Abnormality of midbrain morphology (HP:0002418) | 4.01575062 |
| 6 | Pancreatic fibrosis (HP:0100732) | 3.92855662 |
| 7 | Polyphagia (HP:0002591) | 3.85793619 |
| 8 | Medial flaring of the eyebrow (HP:0010747) | 3.81442847 |
| 9 | Congenital stationary night blindness (HP:0007642) | 3.73998499 |
| 10 | Stenosis of the external auditory canal (HP:0000402) | 3.68425569 |
| 11 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 3.67804180 |
| 12 | Asplenia (HP:0001746) | 3.65337594 |
| 13 | Chronic hepatic failure (HP:0100626) | 3.36656786 |
| 14 | Congenital primary aphakia (HP:0007707) | 3.30803020 |
| 15 | Gait imbalance (HP:0002141) | 3.27178576 |
| 16 | Male pseudohermaphroditism (HP:0000037) | 3.24802041 |
| 17 | Abnormality of glycolysis (HP:0004366) | 3.22782135 |
| 18 | Abnormal sex determination (HP:0012244) | 3.18066491 |
| 19 | Sex reversal (HP:0012245) | 3.18066491 |
| 20 | Papilledema (HP:0001085) | 2.90344399 |
| 21 | Nephrogenic diabetes insipidus (HP:0009806) | 2.89512424 |
| 22 | Nephronophthisis (HP:0000090) | 2.82493014 |
| 23 | Cystic liver disease (HP:0006706) | 2.80977755 |
| 24 | Occipital encephalocele (HP:0002085) | 2.74840810 |
| 25 | Reticulocytopenia (HP:0001896) | 2.73909433 |
| 26 | Fair hair (HP:0002286) | 2.73517497 |
| 27 | Failure to thrive in infancy (HP:0001531) | 2.64971815 |
| 28 | Acute necrotizing encephalopathy (HP:0006965) | 2.62106377 |
| 29 | Exotropia (HP:0000577) | 2.57910822 |
| 30 | Mitochondrial inheritance (HP:0001427) | 2.54549442 |
| 31 | Birth length less than 3rd percentile (HP:0003561) | 2.53291646 |
| 32 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.52790492 |
| 33 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.49118980 |
| 34 | Abnormality of the labia minora (HP:0012880) | 2.48988080 |
| 35 | Anencephaly (HP:0002323) | 2.48548925 |
| 36 | Gonadotropin excess (HP:0000837) | 2.47946333 |
| 37 | Vaginal atresia (HP:0000148) | 2.47801497 |
| 38 | Concave nail (HP:0001598) | 2.43676118 |
| 39 | Impaired proprioception (HP:0010831) | 2.43174684 |
| 40 | Narrow forehead (HP:0000341) | 2.42211026 |
| 41 | Abnormal auditory evoked potentials (HP:0006958) | 2.42043604 |
| 42 | Genital tract atresia (HP:0001827) | 2.39998635 |
| 43 | Postaxial foot polydactyly (HP:0001830) | 2.39627778 |
| 44 | Abnormality of the renal medulla (HP:0100957) | 2.38785582 |
| 45 | Tubular atrophy (HP:0000092) | 2.37191899 |
| 46 | Exercise-induced muscle cramps (HP:0003710) | 2.32175766 |
| 47 | Poor coordination (HP:0002370) | 2.31447775 |
| 48 | Supernumerary spleens (HP:0009799) | 2.29198284 |
| 49 | Progressive cerebellar ataxia (HP:0002073) | 2.28372179 |
| 50 | Large for gestational age (HP:0001520) | 2.28056970 |
| 51 | Abnormal hemoglobin (HP:0011902) | 2.26845857 |
| 52 | Specific learning disability (HP:0001328) | 2.23158774 |
| 53 | Small hand (HP:0200055) | 2.22332765 |
| 54 | Hypoplasia of the uterus (HP:0000013) | 2.20001801 |
| 55 | Focal motor seizures (HP:0011153) | 2.19103566 |
| 56 | Increased CSF lactate (HP:0002490) | 2.18656706 |
| 57 | Hepatocellular necrosis (HP:0001404) | 2.18195978 |
| 58 | Hip dysplasia (HP:0001385) | 2.16755123 |
| 59 | Broad-based gait (HP:0002136) | 2.16089272 |
| 60 | Shawl scrotum (HP:0000049) | 2.15487663 |
| 61 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.10500623 |
| 62 | Acute encephalopathy (HP:0006846) | 2.10460251 |
| 63 | Progressive macrocephaly (HP:0004481) | 2.08794945 |
| 64 | Primary amenorrhea (HP:0000786) | 2.04516487 |
| 65 | Oligomenorrhea (HP:0000876) | 2.04181498 |
| 66 | Abnormal tarsal ossification (HP:0008369) | 2.03298756 |
| 67 | Fibular aplasia (HP:0002990) | 2.02402756 |
| 68 | Sclerocornea (HP:0000647) | 2.00176986 |
| 69 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.97328465 |
| 70 | Abnormal eating behavior (HP:0100738) | 1.96652897 |
| 71 | Meckel diverticulum (HP:0002245) | 1.94558559 |
| 72 | Growth hormone deficiency (HP:0000824) | 1.93994959 |
| 73 | Postaxial hand polydactyly (HP:0001162) | 1.90907456 |
| 74 | Cerebral edema (HP:0002181) | 1.90696985 |
| 75 | Oligodactyly (hands) (HP:0001180) | 1.90678986 |
| 76 | Poor head control (HP:0002421) | 1.90173288 |
| 77 | Broad foot (HP:0001769) | 1.89719032 |
| 78 | Micropenis (HP:0000054) | 1.87847883 |
| 79 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.87702729 |
| 80 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 1.86842459 |
| 81 | Congenital hepatic fibrosis (HP:0002612) | 1.85621369 |
| 82 | Astigmatism (HP:0000483) | 1.84336004 |
| 83 | Short foot (HP:0001773) | 1.83116738 |
| 84 | Irregular epiphyses (HP:0010582) | 1.82783411 |
| 85 | Abnormality of the ileum (HP:0001549) | 1.82743794 |
| 86 | Breast aplasia (HP:0100783) | 1.82556508 |
| 87 | Generalized hypopigmentation of hair (HP:0011358) | 1.81211522 |
| 88 | Adrenal hypoplasia (HP:0000835) | 1.81101399 |
| 89 | Hepatic necrosis (HP:0002605) | 1.80685857 |
| 90 | Dandy-Walker malformation (HP:0001305) | 1.80338548 |
| 91 | Increased serum pyruvate (HP:0003542) | 1.78496890 |
| 92 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.78187506 |
| 93 | Aganglionic megacolon (HP:0002251) | 1.77128694 |
| 94 | Neoplasm of the adrenal cortex (HP:0100641) | 1.76909200 |
| 95 | Protruding tongue (HP:0010808) | 1.76463138 |
| 96 | Type II lissencephaly (HP:0007260) | 1.75595243 |
| 97 | Scrotal hypoplasia (HP:0000046) | 1.74505978 |
| 98 | Depressed nasal ridge (HP:0000457) | 1.72522361 |
| 99 | Genetic anticipation (HP:0003743) | 1.72264358 |
| 100 | Holoprosencephaly (HP:0001360) | 1.71621235 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 5.09141914 |
| 2 | ZAK | 3.02779831 |
| 3 | NEK1 | 2.98607471 |
| 4 | MKNK2 | 2.89031044 |
| 5 | BCR | 2.81994223 |
| 6 | DYRK2 | 2.77639172 |
| 7 | MINK1 | 2.72618593 |
| 8 | TRIM28 | 2.68298923 |
| 9 | PIK3CA | 2.39759059 |
| 10 | PINK1 | 2.39263948 |
| 11 | MKNK1 | 2.15690262 |
| 12 | NTRK2 | 1.95672771 |
| 13 | ERBB3 | 1.90269340 |
| 14 | MAP2K7 | 1.89710338 |
| 15 | BCKDK | 1.84354625 |
| 16 | EPHB2 | 1.84089312 |
| 17 | BMPR2 | 1.82471482 |
| 18 | GRK1 | 1.64590655 |
| 19 | TIE1 | 1.63270482 |
| 20 | DYRK3 | 1.58057567 |
| 21 | BMPR1B | 1.57350162 |
| 22 | SIK3 | 1.56235036 |
| 23 | STK16 | 1.50681117 |
| 24 | NTRK3 | 1.35078348 |
| 25 | MST1R | 1.33500361 |
| 26 | KSR1 | 1.26731732 |
| 27 | TGFBR1 | 1.22349267 |
| 28 | CASK | 1.19032687 |
| 29 | AKT3 | 1.14663001 |
| 30 | CDK19 | 1.14318375 |
| 31 | EPHA4 | 1.14185219 |
| 32 | DYRK1B | 1.13789611 |
| 33 | PASK | 1.13605227 |
| 34 | MAPK15 | 1.08095930 |
| 35 | PHKG2 | 1.05055937 |
| 36 | PHKG1 | 1.05055937 |
| 37 | MAP3K4 | 1.01622852 |
| 38 | TNIK | 0.99187463 |
| 39 | FRK | 0.95605637 |
| 40 | FGFR1 | 0.95024779 |
| 41 | PRKCG | 0.93582637 |
| 42 | TYRO3 | 0.92416096 |
| 43 | NUAK1 | 0.88970103 |
| 44 | MAPK7 | 0.86769483 |
| 45 | EIF2AK3 | 0.86215659 |
| 46 | MAP3K12 | 0.85990777 |
| 47 | WNK4 | 0.85143114 |
| 48 | WNK3 | 0.84241428 |
| 49 | FER | 0.81014377 |
| 50 | PLK4 | 0.79970252 |
| 51 | PDK2 | 0.74796324 |
| 52 | ADRBK2 | 0.73974563 |
| 53 | AURKB | 0.72179473 |
| 54 | CSNK1G2 | 0.71881930 |
| 55 | MARK1 | 0.70642349 |
| 56 | VRK1 | 0.70213561 |
| 57 | ADRBK1 | 0.69136817 |
| 58 | NLK | 0.67900816 |
| 59 | CAMKK2 | 0.67886154 |
| 60 | SRPK1 | 0.65853549 |
| 61 | TEC | 0.64021347 |
| 62 | CCNB1 | 0.63031730 |
| 63 | ERBB4 | 0.61176239 |
| 64 | TNK2 | 0.59964092 |
| 65 | DAPK3 | 0.55811119 |
| 66 | CSNK1G1 | 0.54885438 |
| 67 | PLK1 | 0.51405869 |
| 68 | DYRK1A | 0.50925513 |
| 69 | CSNK1A1L | 0.50842888 |
| 70 | PRKACA | 0.50275587 |
| 71 | CAMK2A | 0.50250921 |
| 72 | ICK | 0.50057334 |
| 73 | PAK3 | 0.49178851 |
| 74 | GRK7 | 0.47448140 |
| 75 | RPS6KA5 | 0.47377942 |
| 76 | PIM1 | 0.47234665 |
| 77 | PRKCE | 0.43445453 |
| 78 | AKT2 | 0.43001920 |
| 79 | CSNK1A1 | 0.42904460 |
| 80 | INSR | 0.42194681 |
| 81 | CHEK2 | 0.41681379 |
| 82 | CSNK1G3 | 0.40323805 |
| 83 | WEE1 | 0.40048991 |
| 84 | MET | 0.39808676 |
| 85 | SGK223 | 0.39509886 |
| 86 | SGK494 | 0.39509886 |
| 87 | ITK | 0.39341136 |
| 88 | MAPK13 | 0.38099675 |
| 89 | PLK3 | 0.37485672 |
| 90 | CDK8 | 0.37292343 |
| 91 | AURKA | 0.37206753 |
| 92 | PRKCQ | 0.34679223 |
| 93 | OBSCN | 0.34344238 |
| 94 | CSNK1E | 0.33538427 |
| 95 | SRC | 0.32235767 |
| 96 | IGF1R | 0.32073915 |
| 97 | EGFR | 0.31479585 |
| 98 | LRRK2 | 0.31247934 |
| 99 | ERBB2 | 0.31206863 |
| 100 | INSRR | 0.28549827 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.44833696 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.76754075 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.17410423 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.03345713 |
| 5 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.97767178 |
| 6 | Basal transcription factors_Homo sapiens_hsa03022 | 2.84594517 |
| 7 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.50969961 |
| 8 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.18255541 |
| 9 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.16559930 |
| 10 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.08536049 |
| 11 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.00970429 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 1.75706928 |
| 13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.68372895 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 1.66215475 |
| 15 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.64352882 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 1.60856464 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.58717353 |
| 18 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.55432674 |
| 19 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.53474879 |
| 20 | Phototransduction_Homo sapiens_hsa04744 | 1.51328475 |
| 21 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.49080511 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.47620583 |
| 23 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.43053899 |
| 24 | Morphine addiction_Homo sapiens_hsa05032 | 1.38779833 |
| 25 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.35399256 |
| 26 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.35041964 |
| 27 | GABAergic synapse_Homo sapiens_hsa04727 | 1.33416129 |
| 28 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.28061131 |
| 29 | Alcoholism_Homo sapiens_hsa05034 | 1.26810087 |
| 30 | Homologous recombination_Homo sapiens_hsa03440 | 1.20576122 |
| 31 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.17104047 |
| 32 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.16174322 |
| 33 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.15774587 |
| 34 | Nicotine addiction_Homo sapiens_hsa05033 | 1.14924333 |
| 35 | Taste transduction_Homo sapiens_hsa04742 | 1.12496707 |
| 36 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.10503513 |
| 37 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.08666041 |
| 38 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.06206865 |
| 39 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.03881633 |
| 40 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.99853984 |
| 41 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.98838231 |
| 42 | Circadian entrainment_Homo sapiens_hsa04713 | 0.97793406 |
| 43 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.91527348 |
| 44 | Proteasome_Homo sapiens_hsa03050 | 0.91274190 |
| 45 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.91104210 |
| 46 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.89747091 |
| 47 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.89665130 |
| 48 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.89521941 |
| 49 | Axon guidance_Homo sapiens_hsa04360 | 0.89323320 |
| 50 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.87183666 |
| 51 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.86261104 |
| 52 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.82405875 |
| 53 | Retinol metabolism_Homo sapiens_hsa00830 | 0.80955609 |
| 54 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.80170519 |
| 55 | Long-term depression_Homo sapiens_hsa04730 | 0.80135845 |
| 56 | Gap junction_Homo sapiens_hsa04540 | 0.79903801 |
| 57 | RNA polymerase_Homo sapiens_hsa03020 | 0.77807577 |
| 58 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.75625035 |
| 59 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.75391215 |
| 60 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.74473703 |
| 61 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.74108512 |
| 62 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.73882457 |
| 63 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.73813984 |
| 64 | Melanogenesis_Homo sapiens_hsa04916 | 0.72949960 |
| 65 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.68794311 |
| 66 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.67605123 |
| 67 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.66182421 |
| 68 | Bile secretion_Homo sapiens_hsa04976 | 0.65835624 |
| 69 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.65344889 |
| 70 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.63445388 |
| 71 | Insulin secretion_Homo sapiens_hsa04911 | 0.63347031 |
| 72 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.63003236 |
| 73 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.62531854 |
| 74 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.61861958 |
| 75 | Carbon metabolism_Homo sapiens_hsa01200 | 0.60454172 |
| 76 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.60367609 |
| 77 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.59617826 |
| 78 | Metabolic pathways_Homo sapiens_hsa01100 | 0.57626267 |
| 79 | Purine metabolism_Homo sapiens_hsa00230 | 0.55708583 |
| 80 | Peroxisome_Homo sapiens_hsa04146 | 0.53460683 |
| 81 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.52619915 |
| 82 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.52468467 |
| 83 | Mismatch repair_Homo sapiens_hsa03430 | 0.50862002 |
| 84 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.50783873 |
| 85 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.50324202 |
| 86 | Tight junction_Homo sapiens_hsa04530 | 0.48211139 |
| 87 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.47538659 |
| 88 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.47426967 |
| 89 | RNA transport_Homo sapiens_hsa03013 | 0.46428438 |
| 90 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.44185584 |
| 91 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.43794878 |
| 92 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.43423126 |
| 93 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.43413271 |
| 94 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.43151144 |
| 95 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.42513078 |
| 96 | Olfactory transduction_Homo sapiens_hsa04740 | 0.42365240 |
| 97 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.41918457 |
| 98 | Salivary secretion_Homo sapiens_hsa04970 | 0.37736235 |
| 99 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.37575962 |
| 100 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.37287619 |

