Rank | Gene Set | Z-score |
---|---|---|
1 | ncRNA 3-end processing (GO:0043628) | 9.63044318 |
2 | ATP synthesis coupled proton transport (GO:0015986) | 9.51152914 |
3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 9.51152914 |
4 | * mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 9.14449824 |
5 | * respiratory electron transport chain (GO:0022904) | 8.46006205 |
6 | * electron transport chain (GO:0022900) | 8.23790680 |
7 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 7.63561701 |
8 | oxidative phosphorylation (GO:0006119) | 5.83698545 |
9 | ATP biosynthetic process (GO:0006754) | 5.37809192 |
10 | sarcomere organization (GO:0045214) | 5.26381569 |
11 | hydrogen ion transmembrane transport (GO:1902600) | 4.96185575 |
12 | GMP metabolic process (GO:0046037) | 4.95383260 |
13 | protein complex biogenesis (GO:0070271) | 4.94002025 |
14 | tricarboxylic acid cycle (GO:0006099) | 4.92463662 |
15 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 4.87935324 |
16 | ribosomal large subunit biogenesis (GO:0042273) | 4.86387034 |
17 | chaperone-mediated protein transport (GO:0072321) | 4.85770079 |
18 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.81368722 |
19 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.81368722 |
20 | NADH dehydrogenase complex assembly (GO:0010257) | 4.81368722 |
21 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 4.80745498 |
22 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.79417204 |
23 | inner mitochondrial membrane organization (GO:0007007) | 4.71789846 |
24 | viral life cycle (GO:0019058) | 4.63840449 |
25 | actin-myosin filament sliding (GO:0033275) | 4.61243952 |
26 | muscle filament sliding (GO:0030049) | 4.61243952 |
27 | heart contraction (GO:0060047) | 4.57064449 |
28 | heart process (GO:0003015) | 4.57064449 |
29 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.56740337 |
30 | cellular component biogenesis (GO:0044085) | 4.55746217 |
31 | protein neddylation (GO:0045116) | 4.46947499 |
32 | cellular protein complex disassembly (GO:0043624) | 4.44617365 |
33 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.37689966 |
34 | regulation of oxidative phosphorylation (GO:0002082) | 4.35912391 |
35 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 4.34118546 |
36 | pyrimidine-containing compound salvage (GO:0008655) | 4.32433122 |
37 | pyrimidine nucleoside salvage (GO:0043097) | 4.32433122 |
38 | proton transport (GO:0015992) | 4.31700934 |
39 | hydrogen transport (GO:0006818) | 4.22932614 |
40 | inositol phosphate dephosphorylation (GO:0046855) | 4.18939920 |
41 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 4.18939920 |
42 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.13094888 |
43 | tricarboxylic acid metabolic process (GO:0072350) | 4.06414395 |
44 | 2-oxoglutarate metabolic process (GO:0006103) | 4.04162429 |
45 | regulation of sister chromatid cohesion (GO:0007063) | 3.98562819 |
46 | quinone biosynthetic process (GO:1901663) | 3.90096642 |
47 | ubiquinone biosynthetic process (GO:0006744) | 3.90096642 |
48 | cardiac myofibril assembly (GO:0055003) | 3.86518270 |
49 | translational initiation (GO:0006413) | 3.85232933 |
50 | myofibril assembly (GO:0030239) | 3.84749514 |
51 | DNA deamination (GO:0045006) | 3.81757862 |
52 | nucleoside salvage (GO:0043174) | 3.81548029 |
53 | ribosomal small subunit biogenesis (GO:0042274) | 3.76766138 |
54 | prostanoid biosynthetic process (GO:0046457) | 3.75761111 |
55 | prostaglandin biosynthetic process (GO:0001516) | 3.75761111 |
56 | nucleoside triphosphate biosynthetic process (GO:0009142) | 3.75356880 |
57 | regulation of mitochondrial translation (GO:0070129) | 3.73732290 |
58 | inositol phosphate catabolic process (GO:0071545) | 3.73107541 |
59 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.72216439 |
60 | regulation of cellular respiration (GO:0043457) | 3.70842820 |
61 | RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502) | 3.70456082 |
62 | protein complex disassembly (GO:0043241) | 3.68845985 |
63 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 3.68500887 |
64 | aerobic respiration (GO:0009060) | 3.67765267 |
65 | mitochondrial transport (GO:0006839) | 3.66897466 |
66 | actin-mediated cell contraction (GO:0070252) | 3.66175476 |
67 | regulation of relaxation of muscle (GO:1901077) | 3.61592751 |
68 | cardiac muscle tissue morphogenesis (GO:0055008) | 3.56333481 |
69 | viral transcription (GO:0019083) | 3.56020646 |
70 | primary alcohol catabolic process (GO:0034310) | 3.55093185 |
71 | intracellular protein transmembrane import (GO:0044743) | 3.54933888 |
72 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 3.54257176 |
73 | ubiquinone metabolic process (GO:0006743) | 3.53653884 |
74 | proteasome assembly (GO:0043248) | 3.50437407 |
75 | protein import into peroxisome matrix (GO:0016558) | 3.50242728 |
76 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 3.47274453 |
77 | cardiac muscle contraction (GO:0060048) | 3.45797310 |
78 | NADH metabolic process (GO:0006734) | 3.45602958 |
79 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 3.45194218 |
80 | sequestering of actin monomers (GO:0042989) | 3.43736149 |
81 | macromolecular complex disassembly (GO:0032984) | 3.41890391 |
82 | purine ribonucleoside monophosphate biosynthetic process (GO:0009168) | 3.40251935 |
83 | purine nucleoside monophosphate biosynthetic process (GO:0009127) | 3.40251935 |
84 | protein targeting to mitochondrion (GO:0006626) | 3.39121823 |
85 | pseudouridine synthesis (GO:0001522) | 3.38790854 |
86 | respiratory chain complex IV assembly (GO:0008535) | 3.37335693 |
87 | response to muscle activity (GO:0014850) | 3.37007264 |
88 | establishment of protein localization to mitochondrion (GO:0072655) | 3.36612007 |
89 | regulation of actin filament-based movement (GO:1903115) | 3.35403382 |
90 | translational termination (GO:0006415) | 3.34708512 |
91 | purine-containing compound salvage (GO:0043101) | 3.34304882 |
92 | regulation of G0 to G1 transition (GO:0070316) | 3.33970719 |
93 | protein targeting to membrane (GO:0006612) | 3.32878186 |
94 | cytochrome complex assembly (GO:0017004) | 3.31781486 |
95 | maturation of SSU-rRNA (GO:0030490) | 3.29734410 |
96 | * generation of precursor metabolites and energy (GO:0006091) | 3.24929488 |
97 | ribosomal small subunit assembly (GO:0000028) | 3.22766192 |
98 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 3.21887116 |
99 | cytidine catabolic process (GO:0006216) | 3.21828864 |
100 | cytidine deamination (GO:0009972) | 3.21828864 |
101 | cytidine metabolic process (GO:0046087) | 3.21828864 |
102 | rRNA processing (GO:0006364) | 3.21251252 |
103 | regulation of skeletal muscle contraction (GO:0014819) | 3.20826508 |
104 | cardiac muscle cell development (GO:0055013) | 3.20768303 |
105 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 3.20702721 |
106 | muscle tissue morphogenesis (GO:0060415) | 3.20419321 |
107 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 3.18980697 |
108 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.16673322 |
109 | cotranslational protein targeting to membrane (GO:0006613) | 3.16610781 |
110 | adult heart development (GO:0007512) | 3.15289590 |
111 | regulation of cell communication by electrical coupling (GO:0010649) | 3.15247234 |
112 | protein targeting to ER (GO:0045047) | 3.13674804 |
113 | GTP biosynthetic process (GO:0006183) | 3.13376784 |
114 | protein maturation by protein folding (GO:0022417) | 3.12411506 |
115 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.12096786 |
116 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 3.11610977 |
117 | negative regulation of protein localization to cell surface (GO:2000009) | 3.10468245 |
118 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 3.08339191 |
119 | phosphatidylglycerol biosynthetic process (GO:0006655) | 3.08275642 |
120 | protein localization to mitochondrion (GO:0070585) | 3.07091256 |
121 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.05820302 |
122 | negative regulation of B cell apoptotic process (GO:0002903) | 3.03838322 |
123 | rRNA metabolic process (GO:0016072) | 3.03768879 |
124 | protein localization to endoplasmic reticulum (GO:0070972) | 3.02356768 |
125 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.01834344 |
126 | termination of RNA polymerase III transcription (GO:0006386) | 3.01834344 |
127 | succinate metabolic process (GO:0006105) | 3.01037222 |
128 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.00936921 |
129 | heart trabecula formation (GO:0060347) | 2.99945861 |
130 | translational elongation (GO:0006414) | 2.95961533 |
131 | cardiac cell development (GO:0055006) | 2.94880569 |
132 | purine ribonucleoside biosynthetic process (GO:0046129) | 2.93626435 |
133 | purine nucleoside biosynthetic process (GO:0042451) | 2.93626435 |
134 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.92693448 |
135 | negative regulation of Ras GTPase activity (GO:0034261) | 2.91789755 |
136 | creatine metabolic process (GO:0006600) | 2.91070512 |
137 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.90368173 |
138 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 2.90331507 |
139 | regulation of coenzyme metabolic process (GO:0051196) | 2.90121164 |
140 | regulation of cofactor metabolic process (GO:0051193) | 2.90121164 |
141 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.86842308 |
142 | striated muscle contraction (GO:0006941) | 2.86370345 |
143 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 2.86284188 |
144 | deoxyribonucleotide catabolic process (GO:0009264) | 2.82413706 |
145 | translation (GO:0006412) | 2.82275578 |
146 | regulation of cholesterol biosynthetic process (GO:0045540) | 2.82001908 |
147 | iron-sulfur cluster assembly (GO:0016226) | 2.81694366 |
148 | metallo-sulfur cluster assembly (GO:0031163) | 2.81694366 |
149 | mitochondrion morphogenesis (GO:0070584) | 2.81616482 |
150 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 2.81265635 |
151 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.76026370 |
152 | mRNA catabolic process (GO:0006402) | 2.71018550 |
153 | intracellular protein transmembrane transport (GO:0065002) | 2.69615449 |
154 | negative regulation of ligase activity (GO:0051352) | 2.69000340 |
155 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 10.1440825 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 5.00368365 |
2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.33707729 |
3 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.00376881 |
4 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.83401674 |
5 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.71630854 |
6 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.71281546 |
7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.55603569 |
8 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.50726656 |
9 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.42742701 |
10 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 3.36036950 |
11 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.33050272 |
12 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.24458025 |
13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.06478883 |
14 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.77120307 |
15 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.74928569 |
16 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.74926344 |
17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.57048725 |
18 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.55721336 |
19 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 2.52876006 |
20 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.48637532 |
21 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.43609133 |
22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.24256923 |
23 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.11779473 |
24 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.03305620 |
25 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.90173086 |
26 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.86010133 |
27 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.82988573 |
28 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.76070820 |
29 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.70665570 |
30 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.70505909 |
31 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.68930702 |
32 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.65925742 |
33 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.52897535 |
34 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.51993926 |
35 | * CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.49124859 |
36 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.46088034 |
37 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.45748365 |
38 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.44951831 |
39 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.43962519 |
40 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.43637778 |
41 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.41300728 |
42 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.40542750 |
43 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.39087630 |
44 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.38101473 |
45 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.37509102 |
46 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.37398890 |
47 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.37104121 |
48 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34263757 |
49 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.33999483 |
50 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.32905954 |
51 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.31215195 |
52 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.29520813 |
53 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.27384482 |
54 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.27027623 |
55 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.26179846 |
56 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.26045593 |
57 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.25718425 |
58 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.25648362 |
59 | P68_20966046_ChIP-Seq_HELA_Human | 1.25302778 |
60 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.24172690 |
61 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.23634173 |
62 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.21554228 |
63 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.20824119 |
64 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.20808260 |
65 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.20357599 |
66 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.20350852 |
67 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.18715977 |
68 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.17927523 |
69 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.17867076 |
70 | VDR_22108803_ChIP-Seq_LS180_Human | 1.17068880 |
71 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.12905274 |
72 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.12701271 |
73 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.12485339 |
74 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.09633390 |
75 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.09612282 |
76 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.08553643 |
77 | * SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.07984639 |
78 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06265785 |
79 | P300_27268052_Chip-Seq_Bcells_Human | 1.05798187 |
80 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.05269984 |
81 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.04889169 |
82 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.04336598 |
83 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.02205746 |
84 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.02047204 |
85 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.00884877 |
86 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 1.00795567 |
87 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.00432262 |
88 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.00250116 |
89 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.00088957 |
90 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.99035652 |
91 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.98828362 |
92 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.98344433 |
93 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 0.98229473 |
94 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.98212089 |
95 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.97144219 |
96 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.97032639 |
97 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96810175 |
98 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.96473122 |
99 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.96023642 |
100 | ERA_21632823_ChIP-Seq_H3396_Human | 0.95600327 |
101 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.95020728 |
102 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.91842341 |
103 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.91473050 |
104 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.90315054 |
105 | LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.88923740 |
106 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.88875064 |
107 | * CTCF_27219007_Chip-Seq_Bcells_Human | 0.87851408 |
108 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 0.87685594 |
109 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.87452546 |
110 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.87373621 |
111 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.87135568 |
112 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.87125957 |
113 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.86619905 |
114 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.86355296 |
115 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.85995806 |
116 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 0.85599053 |
117 | SA1_27219007_Chip-Seq_Bcells_Human | 0.85256424 |
118 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.85225915 |
119 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.84937196 |
120 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.83434712 |
121 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.83084561 |
122 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.82715231 |
123 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.82629009 |
124 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.80897059 |
125 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.80295857 |
126 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.80055093 |
127 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.79757893 |
128 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.79215278 |
129 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.78820509 |
130 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.76887910 |
131 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.75597872 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002837_dystrophic_cardiac_calcinosis | 6.69691493 |
2 | MP0003646_muscle_fatigue | 6.26187972 |
3 | MP0003879_abnormal_hair_cell | 4.26954511 |
4 | MP0006082_CNS_inflammation | 4.23022163 |
5 | MP0000751_myopathy | 4.05777503 |
6 | MP0001873_stomach_inflammation | 4.00748121 |
7 | MP0000749_muscle_degeneration | 3.99132290 |
8 | MP0004084_abnormal_cardiac_muscle | 3.95984542 |
9 | MP0004036_abnormal_muscle_relaxation | 3.74689480 |
10 | MP0004215_abnormal_myocardial_fiber | 3.53926570 |
11 | MP0006036_abnormal_mitochondrial_physio | 3.22654450 |
12 | MP0005330_cardiomyopathy | 3.21446504 |
13 | MP0003121_genomic_imprinting | 2.76068931 |
14 | MP0003137_abnormal_impulse_conducting | 2.49106379 |
15 | MP0009780_abnormal_chondrocyte_physiolo | 2.46541737 |
16 | MP0001529_abnormal_vocalization | 2.46334106 |
17 | MP0002972_abnormal_cardiac_muscle | 2.46247701 |
18 | MP0003806_abnormal_nucleotide_metabolis | 2.39049085 |
19 | MP0000750_abnormal_muscle_regeneration | 2.18215781 |
20 | MP0006035_abnormal_mitochondrial_morpho | 2.12292512 |
21 | MP0002106_abnormal_muscle_physiology | 2.11331623 |
22 | MP0009379_abnormal_foot_pigmentation | 2.11315843 |
23 | MP0004087_abnormal_muscle_fiber | 2.10544855 |
24 | MP0005620_abnormal_muscle_contractility | 2.06223142 |
25 | MP0005075_abnormal_melanosome_morpholog | 2.04668010 |
26 | MP0006292_abnormal_olfactory_placode | 2.02109696 |
27 | MP0005385_cardiovascular_system_phenoty | 1.94882668 |
28 | MP0001544_abnormal_cardiovascular_syste | 1.94882668 |
29 | MP0002332_abnormal_exercise_endurance | 1.91282775 |
30 | MP0008775_abnormal_heart_ventricle | 1.89661326 |
31 | MP0009333_abnormal_splenocyte_physiolog | 1.83500725 |
32 | MP0002933_joint_inflammation | 1.81691307 |
33 | MP0001905_abnormal_dopamine_level | 1.78623885 |
34 | MP0002269_muscular_atrophy | 1.78125298 |
35 | MP0004145_abnormal_muscle_electrophysio | 1.77125588 |
36 | MP0003693_abnormal_embryo_hatching | 1.66558503 |
37 | MP0006138_congestive_heart_failure | 1.65905588 |
38 | MP0005369_muscle_phenotype | 1.64652054 |
39 | MP0004130_abnormal_muscle_cell | 1.61596996 |
40 | MP0000747_muscle_weakness | 1.56870180 |
41 | MP0004085_abnormal_heartbeat | 1.56550675 |
42 | MP0004484_altered_response_of | 1.54590450 |
43 | MP0000759_abnormal_skeletal_muscle | 1.51438701 |
44 | MP0003186_abnormal_redox_activity | 1.51205218 |
45 | MP0000015_abnormal_ear_pigmentation | 1.45142292 |
46 | MP0006276_abnormal_autonomic_nervous | 1.42766543 |
47 | MP0003950_abnormal_plasma_membrane | 1.41986958 |
48 | MP0005379_endocrine/exocrine_gland_phen | 1.41606725 |
49 | MP0010630_abnormal_cardiac_muscle | 1.38124470 |
50 | MP0005451_abnormal_body_composition | 1.36659014 |
51 | MP0003828_pulmonary_edema | 1.34029350 |
52 | MP0003221_abnormal_cardiomyocyte_apopto | 1.32236903 |
53 | MP0004510_myositis | 1.31991017 |
54 | MP0003011_delayed_dark_adaptation | 1.28162935 |
55 | MP0005266_abnormal_metabolism | 1.26515721 |
56 | MP0003123_paternal_imprinting | 1.23316518 |
57 | MP0004142_abnormal_muscle_tone | 1.20234960 |
58 | MP0004043_abnormal_pH_regulation | 1.18679324 |
59 | MP0005174_abnormal_tail_pigmentation | 1.16572332 |
60 | MP0004147_increased_porphyrin_level | 1.16389439 |
61 | MP0002127_abnormal_cardiovascular_syste | 1.13060493 |
62 | MP0005646_abnormal_pituitary_gland | 1.11753891 |
63 | MP0001727_abnormal_embryo_implantation | 1.11004259 |
64 | MP0000343_altered_response_to | 1.09542303 |
65 | MP0003195_calcinosis | 1.06075814 |
66 | MP0003880_abnormal_central_pattern | 1.05616303 |
67 | MP0001968_abnormal_touch/_nociception | 1.04991526 |
68 | MP0005083_abnormal_biliary_tract | 1.04830531 |
69 | MP0005165_increased_susceptibility_to | 0.99448037 |
70 | MP0002095_abnormal_skin_pigmentation | 0.98877838 |
71 | MP0000230_abnormal_systemic_arterial | 0.93575119 |
72 | MP0005381_digestive/alimentary_phenotyp | 0.92905209 |
73 | MP0005332_abnormal_amino_acid | 0.92219202 |
74 | MP0003786_premature_aging | 0.92051585 |
75 | MP0005535_abnormal_body_temperature | 0.88973647 |
76 | MP0005670_abnormal_white_adipose | 0.86822263 |
77 | MP0003136_yellow_coat_color | 0.86750987 |
78 | MP0005671_abnormal_response_to | 0.85527196 |
79 | MP0002277_abnormal_respiratory_mucosa | 0.85360521 |
80 | MP0005551_abnormal_eye_electrophysiolog | 0.85179134 |
81 | MP0009765_abnormal_xenobiotic_induced | 0.83740056 |
82 | MP0002822_catalepsy | 0.82615210 |
83 | MP0001851_eye_inflammation | 0.82493706 |
84 | MP0005636_abnormal_mineral_homeostasis | 0.80636305 |
85 | MP0002234_abnormal_pharynx_morphology | 0.78560735 |
86 | MP0005084_abnormal_gallbladder_morpholo | 0.78409493 |
87 | MP0000372_irregular_coat_pigmentation | 0.77615882 |
88 | MP0002160_abnormal_reproductive_system | 0.77040457 |
89 | MP0009785_altered_susceptibility_to | 0.75871389 |
90 | MP0005376_homeostasis/metabolism_phenot | 0.75097987 |
91 | MP0008058_abnormal_DNA_repair | 0.73916173 |
92 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.73531014 |
93 | MP0001853_heart_inflammation | 0.73080756 |
94 | MP0002638_abnormal_pupillary_reflex | 0.72356435 |
95 | MP0000026_abnormal_inner_ear | 0.72352172 |
96 | MP0000920_abnormal_myelination | 0.71731670 |
97 | MP0008995_early_reproductive_senescence | 0.71478969 |
98 | MP0003656_abnormal_erythrocyte_physiolo | 0.70940317 |
99 | MP0005645_abnormal_hypothalamus_physiol | 0.69784853 |
100 | MP0001986_abnormal_taste_sensitivity | 0.68791015 |
101 | MP0008872_abnormal_physiological_respon | 0.68755635 |
102 | MP0001764_abnormal_homeostasis | 0.68443353 |
103 | MP0003718_maternal_effect | 0.68105054 |
104 | MP0001661_extended_life_span | 0.68001979 |
105 | MP0002272_abnormal_nervous_system | 0.67800242 |
106 | MP0002148_abnormal_hypersensitivity_rea | 0.67640858 |
107 | MP0004924_abnormal_behavior | 0.67441734 |
108 | MP0005386_behavior/neurological_phenoty | 0.67441734 |
109 | MP0002108_abnormal_muscle_morphology | 0.66712708 |
110 | MP0001984_abnormal_olfaction | 0.66701427 |
111 | MP0003938_abnormal_ear_development | 0.65545829 |
112 | MP0005409_darkened_coat_color | 0.65496870 |
113 | MP0000678_abnormal_parathyroid_gland | 0.64738313 |
114 | MP0009764_decreased_sensitivity_to | 0.63895148 |
115 | MP0000538_abnormal_urinary_bladder | 0.62944834 |
116 | MP0010030_abnormal_orbit_morphology | 0.62343431 |
117 | MP0001485_abnormal_pinna_reflex | 0.61313111 |
118 | MP0009643_abnormal_urine_homeostasis | 0.61079274 |
119 | MP0000049_abnormal_middle_ear | 0.60458150 |
120 | MP0005319_abnormal_enzyme/_coenzyme | 0.59732164 |
121 | MP0003567_abnormal_fetal_cardiomyocyte | 0.59715616 |
122 | MP0000681_abnormal_thyroid_gland | 0.57777947 |
123 | MP0008469_abnormal_protein_level | 0.57721136 |
124 | MP0001963_abnormal_hearing_physiology | 0.57144475 |
125 | MP0006072_abnormal_retinal_apoptosis | 0.56333105 |
126 | MP0002736_abnormal_nociception_after | 0.55785068 |
127 | MP0002163_abnormal_gland_morphology | 0.54761449 |
128 | MP0003329_amyloid_beta_deposits | 0.53814926 |
129 | MP0008789_abnormal_olfactory_epithelium | 0.53462376 |
130 | MP0001533_abnormal_skeleton_physiology | 0.52909345 |
131 | MP0005666_abnormal_adipose_tissue | 0.52638399 |
132 | MP0001756_abnormal_urination | 0.51545486 |
133 | MP0002229_neurodegeneration | 0.50069447 |
134 | MP0001970_abnormal_pain_threshold | 0.49670669 |
135 | MP0002132_abnormal_respiratory_system | 0.49430994 |
136 | MP0008875_abnormal_xenobiotic_pharmacok | 0.48838228 |
137 | MP0001440_abnormal_grooming_behavior | 0.48257132 |
138 | MP0002139_abnormal_hepatobiliary_system | 0.48218961 |
139 | MP0001663_abnormal_digestive_system | 0.47405287 |
140 | MP0001664_abnormal_digestion | 0.47007991 |
141 | MP0009840_abnormal_foam_cell | 0.46954166 |
142 | MP0002735_abnormal_chemical_nociception | 0.45727542 |
143 | MP0003724_increased_susceptibility_to | 0.45604722 |
144 | MP0004133_heterotaxia | 0.44846278 |
145 | MP0000013_abnormal_adipose_tissue | 0.44448995 |
146 | MP0005085_abnormal_gallbladder_physiolo | 0.44434082 |
147 | MP0002876_abnormal_thyroid_physiology | 0.44255229 |
148 | MP0002078_abnormal_glucose_homeostasis | 0.43340649 |
149 | MP0005408_hypopigmentation | 0.42607033 |
150 | MP0000358_abnormal_cell_content/ | 0.42034890 |
151 | MP0005410_abnormal_fertilization | 0.38695989 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Round ear (HP:0100830) | 7.28550487 |
2 | Acute necrotizing encephalopathy (HP:0006965) | 7.04127061 |
3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 6.58560755 |
4 | Mitochondrial inheritance (HP:0001427) | 6.33210700 |
5 | Abnormality of macular pigmentation (HP:0008002) | 6.07460568 |
6 | Acute encephalopathy (HP:0006846) | 5.98719996 |
7 | Constricted visual fields (HP:0001133) | 5.82736821 |
8 | Progressive macrocephaly (HP:0004481) | 5.75320906 |
9 | Metaphyseal cupping (HP:0003021) | 5.66555615 |
10 | Hepatocellular necrosis (HP:0001404) | 5.64506035 |
11 | Hepatic necrosis (HP:0002605) | 5.50669497 |
12 | Striae distensae (HP:0001065) | 5.47173429 |
13 | Increased CSF lactate (HP:0002490) | 5.43317922 |
14 | Cupped ribs (HP:0000887) | 4.87609610 |
15 | Sudden death (HP:0001699) | 4.81410780 |
16 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 4.69113291 |
17 | Cerebral edema (HP:0002181) | 4.59736230 |
18 | Increased hepatocellular lipid droplets (HP:0006565) | 4.58438851 |
19 | Toxemia of pregnancy (HP:0100603) | 4.51081094 |
20 | Lipid accumulation in hepatocytes (HP:0006561) | 4.49610994 |
21 | Volvulus (HP:0002580) | 4.39702961 |
22 | Increased intramyocellular lipid droplets (HP:0012240) | 4.36064268 |
23 | Cone-rod dystrophy (HP:0000548) | 4.29897961 |
24 | Ventricular tachycardia (HP:0004756) | 4.24482694 |
25 | Increased muscle lipid content (HP:0009058) | 4.22265037 |
26 | Calf muscle hypertrophy (HP:0008981) | 4.21257000 |
27 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 4.13059214 |
28 | Muscle hypertrophy of the lower extremities (HP:0008968) | 4.11343854 |
29 | Exercise intolerance (HP:0003546) | 4.11197251 |
30 | Respiratory failure (HP:0002878) | 3.99294886 |
31 | Lactic acidosis (HP:0003128) | 3.97951620 |
32 | Increased serum pyruvate (HP:0003542) | 3.90127927 |
33 | Abnormality of glycolysis (HP:0004366) | 3.90127927 |
34 | Optic disc pallor (HP:0000543) | 3.84575353 |
35 | Renal Fanconi syndrome (HP:0001994) | 3.84412574 |
36 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.75944296 |
37 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.75944296 |
38 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.63816370 |
39 | Attenuation of retinal blood vessels (HP:0007843) | 3.61440740 |
40 | Muscle fiber splitting (HP:0003555) | 3.45437393 |
41 | Increased serum lactate (HP:0002151) | 3.43999558 |
42 | Palpitations (HP:0001962) | 3.41304938 |
43 | Leukodystrophy (HP:0002415) | 3.39349259 |
44 | Exercise-induced myalgia (HP:0003738) | 3.37625456 |
45 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.35817499 |
46 | Lipoatrophy (HP:0100578) | 3.25669300 |
47 | Hyperthyroidism (HP:0000836) | 3.23193613 |
48 | Exercise-induced muscle cramps (HP:0003710) | 3.19296726 |
49 | Exertional dyspnea (HP:0002875) | 3.15264285 |
50 | Myoglobinuria (HP:0002913) | 3.14521988 |
51 | Atrial fibrillation (HP:0005110) | 3.10629138 |
52 | Severe visual impairment (HP:0001141) | 3.05852659 |
53 | 3-Methylglutaconic aciduria (HP:0003535) | 3.04162264 |
54 | Abnormality of the calf musculature (HP:0001430) | 3.01225360 |
55 | Supraventricular tachycardia (HP:0004755) | 2.98745513 |
56 | Large earlobe (HP:0009748) | 2.91370461 |
57 | Primary atrial arrhythmia (HP:0001692) | 2.91278464 |
58 | Supraventricular arrhythmia (HP:0005115) | 2.90555853 |
59 | Rhabdomyolysis (HP:0003201) | 2.88781892 |
60 | Dilated cardiomyopathy (HP:0001644) | 2.85158232 |
61 | Neoplasm of head and neck (HP:0012288) | 2.82788995 |
62 | Esophageal neoplasm (HP:0100751) | 2.82788995 |
63 | Decreased muscle mass (HP:0003199) | 2.77606560 |
64 | Dicarboxylic aciduria (HP:0003215) | 2.75765970 |
65 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.75765970 |
66 | Respiratory difficulties (HP:0002880) | 2.74970243 |
67 | Neuroendocrine neoplasm (HP:0100634) | 2.71293828 |
68 | Pheochromocytoma (HP:0002666) | 2.66697664 |
69 | Lethargy (HP:0001254) | 2.64688766 |
70 | Abnormality of urine glucose concentration (HP:0011016) | 2.62605677 |
71 | Glycosuria (HP:0003076) | 2.62605677 |
72 | Myotonia (HP:0002486) | 2.61776801 |
73 | CNS demyelination (HP:0007305) | 2.57550154 |
74 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.55174394 |
75 | Prolonged QT interval (HP:0001657) | 2.50812947 |
76 | Syncope (HP:0001279) | 2.49735771 |
77 | Abnormality of renal resorption (HP:0011038) | 2.46885656 |
78 | Brushfield spots (HP:0001088) | 2.46748174 |
79 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.42214176 |
80 | Generalized aminoaciduria (HP:0002909) | 2.42187104 |
81 | Oligodontia (HP:0000677) | 2.41998448 |
82 | EMG: myopathic abnormalities (HP:0003458) | 2.41381338 |
83 | Subaortic stenosis (HP:0001682) | 2.40008797 |
84 | Abnormality of the left ventricular outflow tract (HP:0011103) | 2.40008797 |
85 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 2.37912939 |
86 | Lack of skin elasticity (HP:0100679) | 2.33911913 |
87 | Ovoid vertebral bodies (HP:0003300) | 2.33583406 |
88 | Muscle stiffness (HP:0003552) | 2.29627536 |
89 | Broad nasal tip (HP:0000455) | 2.26388743 |
90 | Concave nail (HP:0001598) | 2.22607522 |
91 | Hyporeflexia of lower limbs (HP:0002600) | 2.21497814 |
92 | Emotional lability (HP:0000712) | 2.20929615 |
93 | Femoral bowing (HP:0002980) | 2.19877433 |
94 | Conjunctival hamartoma (HP:0100780) | 2.19835580 |
95 | Abnormal number of erythroid precursors (HP:0012131) | 2.16712846 |
96 | Small hand (HP:0200055) | 2.15994059 |
97 | X-linked dominant inheritance (HP:0001423) | 2.14143238 |
98 | Aplastic anemia (HP:0001915) | 2.13674859 |
99 | Ragged-red muscle fibers (HP:0003200) | 2.11726710 |
100 | Vomiting (HP:0002013) | 2.10953862 |
101 | Hyperphosphaturia (HP:0003109) | 2.09795419 |
102 | Macrocytic anemia (HP:0001972) | 2.08260552 |
103 | Muscle fiber inclusion bodies (HP:0100299) | 2.07054119 |
104 | Tibial bowing (HP:0002982) | 2.05486395 |
105 | Prominent supraorbital ridges (HP:0000336) | 2.04296904 |
106 | Ventricular arrhythmia (HP:0004308) | 2.01104801 |
107 | Nemaline bodies (HP:0003798) | 2.00858749 |
108 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.98983887 |
109 | Testicular atrophy (HP:0000029) | 1.98502129 |
110 | Right ventricular cardiomyopathy (HP:0011663) | 1.97589193 |
111 | Abnormality of lateral ventricle (HP:0030047) | 1.97048384 |
112 | Asymmetric septal hypertrophy (HP:0001670) | 1.96353143 |
113 | Coxa vara (HP:0002812) | 1.95419257 |
114 | Left ventricular hypertrophy (HP:0001712) | 1.94242455 |
115 | Hepatosplenomegaly (HP:0001433) | 1.90188719 |
116 | Ketoacidosis (HP:0001993) | 1.89450697 |
117 | Hyperglycinemia (HP:0002154) | 1.89164578 |
118 | Nausea (HP:0002018) | 1.86306472 |
119 | Hypoglycemic coma (HP:0001325) | 1.85649125 |
120 | IgM deficiency (HP:0002850) | 1.83708681 |
121 | Methylmalonic aciduria (HP:0012120) | 1.83148335 |
122 | Reticulocytopenia (HP:0001896) | 1.82295337 |
123 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.82267415 |
124 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.82230231 |
125 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.82031018 |
126 | Myokymia (HP:0002411) | 1.81689852 |
127 | Palmoplantar keratoderma (HP:0000982) | 1.80841655 |
128 | Gliosis (HP:0002171) | 1.80196897 |
129 | Abnormal urine phosphate concentration (HP:0012599) | 1.77237432 |
130 | Oral leukoplakia (HP:0002745) | 1.76674252 |
131 | Abnormal EKG (HP:0003115) | 1.75050169 |
132 | Epiphyseal stippling (HP:0010655) | 1.75014024 |
133 | Multiple enchondromatosis (HP:0005701) | 1.74533780 |
134 | Recurrent otitis media (HP:0000403) | 1.74325858 |
135 | Cerebral hemorrhage (HP:0001342) | 1.72168102 |
136 | Blindness (HP:0000618) | 1.72074444 |
137 | Hypoplastic left heart (HP:0004383) | 1.71124442 |
138 | Neck muscle weakness (HP:0000467) | 1.70471986 |
139 | Proximal tubulopathy (HP:0000114) | 1.69153694 |
140 | Prenatal maternal abnormality (HP:0002686) | 1.67874969 |
141 | Ventricular fibrillation (HP:0001663) | 1.67150670 |
142 | Heart block (HP:0012722) | 1.66742932 |
143 | Abnormality of alanine metabolism (HP:0010916) | 1.66486348 |
144 | Hyperalaninemia (HP:0003348) | 1.66486348 |
145 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.66486348 |
146 | Progressive visual loss (HP:0000529) | 1.64911185 |
147 | Sparse eyelashes (HP:0000653) | 1.62752162 |
148 | Type I transferrin isoform profile (HP:0003642) | 1.62668469 |
149 | Proximal placement of thumb (HP:0009623) | 1.61823919 |
150 | Rough bone trabeculation (HP:0100670) | 1.60216540 |
151 | Muscle fiber atrophy (HP:0100295) | 1.59780424 |
152 | Cerebral palsy (HP:0100021) | 1.59713823 |
153 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.59696431 |
154 | Abnormality of magnesium homeostasis (HP:0004921) | 1.59486665 |
Rank | Gene Set | Z-score |
---|---|---|
1 | KIT | 5.94141476 |
2 | MYLK | 4.88863827 |
3 | NME2 | 3.95648195 |
4 | VRK2 | 3.36858209 |
5 | OBSCN | 3.33005537 |
6 | FES | 3.17456285 |
7 | BCKDK | 3.12322337 |
8 | NME1 | 3.08073196 |
9 | MAP3K12 | 2.98226829 |
10 | TTN | 2.58787003 |
11 | STK16 | 2.50136216 |
12 | PHKG1 | 2.36712805 |
13 | PHKG2 | 2.36712805 |
14 | MUSK | 2.31694115 |
15 | TEC | 2.29625006 |
16 | PIK3CA | 2.23023016 |
17 | LMTK2 | 2.16645081 |
18 | PBK | 2.16501883 |
19 | GRK7 | 2.04236900 |
20 | LIMK1 | 2.02534575 |
21 | STK39 | 1.89838110 |
22 | PDK3 | 1.80821781 |
23 | PDK4 | 1.80821781 |
24 | CDK19 | 1.72076262 |
25 | IKBKB | 1.70691763 |
26 | WNK4 | 1.68652202 |
27 | TLK1 | 1.68362685 |
28 | BUB1 | 1.66091239 |
29 | DAPK3 | 1.63724123 |
30 | ARAF | 1.54137410 |
31 | ILK | 1.49742620 |
32 | KDR | 1.44139894 |
33 | TESK2 | 1.42212773 |
34 | TIE1 | 1.38815243 |
35 | MAP4K2 | 1.32915456 |
36 | CAMK2D | 1.31400062 |
37 | PIM2 | 1.27836256 |
38 | SIK2 | 1.24637620 |
39 | MAP3K11 | 1.21210947 |
40 | PINK1 | 1.12725550 |
41 | MAP4K1 | 1.08608122 |
42 | ABL2 | 1.05095596 |
43 | PDK2 | 1.03685492 |
44 | MST4 | 1.03406553 |
45 | OXSR1 | 1.02894940 |
46 | GRK5 | 0.99515173 |
47 | ROCK2 | 0.98593265 |
48 | TBK1 | 0.97888396 |
49 | TESK1 | 0.95277634 |
50 | PRPF4B | 0.94312035 |
51 | ZAK | 0.93755180 |
52 | SYK | 0.93283650 |
53 | PKN1 | 0.92918001 |
54 | RPS6KB2 | 0.91340859 |
55 | EIF2AK1 | 0.91229720 |
56 | VRK1 | 0.90260517 |
57 | BLK | 0.85634560 |
58 | ROCK1 | 0.85152743 |
59 | RPS6KL1 | 0.85040167 |
60 | RPS6KC1 | 0.85040167 |
61 | UHMK1 | 0.82594726 |
62 | TAOK2 | 0.80575700 |
63 | STK24 | 0.80439584 |
64 | SRPK1 | 0.77973061 |
65 | ADRBK2 | 0.77826328 |
66 | BRAF | 0.76969265 |
67 | RPS6KA6 | 0.76568903 |
68 | CDK3 | 0.76484458 |
69 | DYRK2 | 0.75180816 |
70 | STK4 | 0.74989479 |
71 | MST1R | 0.72890613 |
72 | RPS6KA5 | 0.72148924 |
73 | GRK1 | 0.69039667 |
74 | CAMK2G | 0.67280646 |
75 | BCR | 0.66413263 |
76 | CAMK2A | 0.64955273 |
77 | MAP2K7 | 0.64657394 |
78 | CSK | 0.64243753 |
79 | TYRO3 | 0.63418693 |
80 | CAMK2B | 0.61036402 |
81 | MAP2K2 | 0.60347619 |
82 | EIF2AK3 | 0.59210250 |
83 | MAPK12 | 0.58789821 |
84 | IKBKE | 0.58326418 |
85 | PRKACA | 0.56762757 |
86 | CCNB1 | 0.55898537 |
87 | IRAK4 | 0.55813699 |
88 | CSF1R | 0.55388727 |
89 | CDC7 | 0.55180742 |
90 | MAP2K6 | 0.53568788 |
91 | DAPK1 | 0.53018054 |
92 | IRAK3 | 0.52235558 |
93 | CSNK1G1 | 0.52184301 |
94 | WNK3 | 0.51742865 |
95 | WEE1 | 0.50990942 |
96 | PTK2B | 0.50565461 |
97 | PAK3 | 0.50224226 |
98 | CDC42BPA | 0.50146216 |
99 | INSRR | 0.49736304 |
100 | ADRBK1 | 0.49665757 |
101 | PRKD1 | 0.47779653 |
102 | NEK1 | 0.46644952 |
103 | EPHB2 | 0.46577669 |
104 | PRKCI | 0.46459177 |
105 | CSNK1G2 | 0.43896349 |
106 | NUAK1 | 0.43056888 |
107 | MAPK4 | 0.42839809 |
108 | AURKA | 0.42376122 |
109 | TNIK | 0.41458269 |
110 | RET | 0.41195314 |
111 | CASK | 0.40426110 |
112 | RPS6KA4 | 0.40338828 |
113 | MAPKAPK5 | 0.40058242 |
114 | INSR | 0.39345240 |
115 | PAK1 | 0.38881180 |
116 | PLK1 | 0.38783508 |
117 | PRKCE | 0.38614517 |
118 | PRKACB | 0.37749103 |
119 | SRC | 0.37727338 |
120 | GRK6 | 0.37542858 |
121 | CSNK2A2 | 0.37487187 |
122 | PRKCA | 0.37253772 |
123 | PIK3CG | 0.37136880 |
124 | AURKB | 0.36287110 |
125 | MAPKAPK3 | 0.35893832 |
126 | PAK4 | 0.35841773 |
127 | RPS6KA2 | 0.34970654 |
128 | TXK | 0.34712720 |
129 | PNCK | 0.34457084 |
130 | EPHA2 | 0.34129475 |
131 | PRKCQ | 0.32921958 |
132 | LRRK2 | 0.32227416 |
133 | CDK11A | 0.32204534 |
134 | DMPK | 0.32201320 |
135 | CSNK1A1L | 0.31988835 |
136 | FGR | 0.31496766 |
137 | CSNK2A1 | 0.31490454 |
138 | PRKCG | 0.31006990 |
139 | IRAK2 | 0.30743507 |
140 | IRAK1 | 0.30164382 |
141 | CSNK1G3 | 0.29919847 |
142 | CSNK1A1 | 0.29559785 |
143 | PRKACG | 0.27928115 |
144 | CDK8 | 0.26937234 |
145 | AKT2 | 0.24713040 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Oxidative phosphorylation_Homo sapiens_hsa00190 | 6.41934719 |
2 | Parkinsons disease_Homo sapiens_hsa05012 | 5.73637156 |
3 | Alzheimers disease_Homo sapiens_hsa05010 | 4.20553057 |
4 | Huntingtons disease_Homo sapiens_hsa05016 | 3.88821332 |
5 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.81593036 |
6 | * Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 3.76633188 |
7 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 3.40321769 |
8 | Ribosome_Homo sapiens_hsa03010 | 3.24422980 |
9 | Proteasome_Homo sapiens_hsa03050 | 3.05078813 |
10 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.15149452 |
11 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.06202873 |
12 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.89945299 |
13 | RNA polymerase_Homo sapiens_hsa03020 | 1.85798174 |
14 | Protein export_Homo sapiens_hsa03060 | 1.71851863 |
15 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.68960598 |
16 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.64354881 |
17 | Carbon metabolism_Homo sapiens_hsa01200 | 1.63347100 |
18 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.58771573 |
19 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.58341642 |
20 | Phototransduction_Homo sapiens_hsa04744 | 1.51942803 |
21 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.45667562 |
22 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.31055614 |
23 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.30178399 |
24 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.25662405 |
25 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.16561897 |
26 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.15228861 |
27 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.12383233 |
28 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.11582165 |
29 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.06476016 |
30 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.06304084 |
31 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.01100932 |
32 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.98685121 |
33 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.94480567 |
34 | * Metabolic pathways_Homo sapiens_hsa01100 | 0.94170125 |
35 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.91353405 |
36 | Peroxisome_Homo sapiens_hsa04146 | 0.87607729 |
37 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.87301658 |
38 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.86955473 |
39 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.84528842 |
40 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.80801781 |
41 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.78269210 |
42 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.77426366 |
43 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.76546901 |
44 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.73508727 |
45 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.73489573 |
46 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.71537559 |
47 | Sulfur relay system_Homo sapiens_hsa04122 | 0.69123714 |
48 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.64483138 |
49 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.62158307 |
50 | Purine metabolism_Homo sapiens_hsa00230 | 0.61176166 |
51 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.61072208 |
52 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.60616118 |
53 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.57464937 |
54 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.55131327 |
55 | DNA replication_Homo sapiens_hsa03030 | 0.54704764 |
56 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.54377892 |
57 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.54027688 |
58 | Galactose metabolism_Homo sapiens_hsa00052 | 0.53338554 |
59 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.52388523 |
60 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.51934517 |
61 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.51549023 |
62 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.51221454 |
63 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.49952588 |
64 | Alcoholism_Homo sapiens_hsa05034 | 0.49639069 |
65 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.49458710 |
66 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.49375555 |
67 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.49372923 |
68 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.48555910 |
69 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.45993130 |
70 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.44518066 |
71 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.41675859 |
72 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.41178670 |
73 | Viral myocarditis_Homo sapiens_hsa05416 | 0.40738869 |
74 | Histidine metabolism_Homo sapiens_hsa00340 | 0.37959320 |
75 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.37864299 |
76 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.37309327 |
77 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.35530306 |
78 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.35442819 |
79 | Spliceosome_Homo sapiens_hsa03040 | 0.34094598 |
80 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.33997219 |
81 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.33350817 |
82 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.33304210 |
83 | Olfactory transduction_Homo sapiens_hsa04740 | 0.33123048 |
84 | RNA degradation_Homo sapiens_hsa03018 | 0.32999993 |
85 | Base excision repair_Homo sapiens_hsa03410 | 0.31526314 |
86 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.30648912 |
87 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.30353017 |
88 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.29241995 |
89 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.28849350 |
90 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.28634634 |
91 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.28017739 |
92 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.26588152 |
93 | Mismatch repair_Homo sapiens_hsa03430 | 0.25183481 |
94 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.24080503 |
95 | Homologous recombination_Homo sapiens_hsa03440 | 0.23937287 |
96 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.23477957 |
97 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.21563972 |
98 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.21396827 |
99 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.19986332 |
100 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.18028383 |
101 | Lysosome_Homo sapiens_hsa04142 | 0.17232713 |
102 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.17159459 |
103 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.16288389 |
104 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.16173456 |
105 | Allograft rejection_Homo sapiens_hsa05330 | 0.15755859 |
106 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.15145054 |
107 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.14575918 |
108 | Phagosome_Homo sapiens_hsa04145 | 0.12757457 |
109 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.10774838 |
110 | Other glycan degradation_Homo sapiens_hsa00511 | 0.10294693 |
111 | Asthma_Homo sapiens_hsa05310 | 0.08426588 |
112 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.07990534 |
113 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.05712157 |
114 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.05019071 |
115 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.03468544 |
116 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.03366109 |
117 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.02201315 |
118 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.01610632 |
119 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.00661443 |
120 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.00609215 |
121 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.00162783 |
122 | Retinol metabolism_Homo sapiens_hsa00830 | -0.0210537 |
123 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | -0.0146965 |