NEDD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)4.67047551
2protein localization to kinetochore (GO:0034501)4.51836125
3mitotic chromosome condensation (GO:0007076)4.48459910
4regulation of spindle organization (GO:0090224)4.42772808
5CENP-A containing nucleosome assembly (GO:0034080)4.39953699
6attachment of spindle microtubules to kinetochore (GO:0008608)4.39052535
7DNA strand elongation involved in DNA replication (GO:0006271)4.27094656
8protein localization to chromosome, centromeric region (GO:0071459)4.20276765
9chromatin remodeling at centromere (GO:0031055)4.18757047
10DNA ligation (GO:0006266)4.17363268
11metaphase plate congression (GO:0051310)4.13587245
12DNA strand elongation (GO:0022616)4.06392869
13regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.05391160
14regulation of centriole replication (GO:0046599)4.02616678
15telomere maintenance via semi-conservative replication (GO:0032201)4.02537346
16regulation of DNA endoreduplication (GO:0032875)3.99571926
17DNA replication checkpoint (GO:0000076)3.97750435
18kinetochore organization (GO:0051383)3.92796238
19telomere maintenance via recombination (GO:0000722)3.88140807
20DNA replication initiation (GO:0006270)3.83719102
21meiotic chromosome segregation (GO:0045132)3.83568043
22DNA replication-independent nucleosome organization (GO:0034724)3.82958645
23DNA replication-independent nucleosome assembly (GO:0006336)3.82958645
24mitotic recombination (GO:0006312)3.81645826
25mitotic nuclear envelope disassembly (GO:0007077)3.78212925
26establishment of chromosome localization (GO:0051303)3.76119288
27DNA unwinding involved in DNA replication (GO:0006268)3.76100843
28mitotic sister chromatid segregation (GO:0000070)3.72289374
29synapsis (GO:0007129)3.68455152
30microtubule depolymerization (GO:0007019)3.67896208
31centriole replication (GO:0007099)3.62419976
32regulation of mitotic spindle organization (GO:0060236)3.61830837
33nucleobase biosynthetic process (GO:0046112)3.61639504
34non-recombinational repair (GO:0000726)3.60474892
35double-strand break repair via nonhomologous end joining (GO:0006303)3.60474892
36resolution of meiotic recombination intermediates (GO:0000712)3.59146283
37histone exchange (GO:0043486)3.56491807
38regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.53897733
39purine nucleobase biosynthetic process (GO:0009113)3.52052269
40nuclear pore organization (GO:0006999)3.51365656
41sister chromatid segregation (GO:0000819)3.51137586
42nuclear pore complex assembly (GO:0051292)3.50067161
43DNA double-strand break processing (GO:0000729)3.45216310
44establishment of integrated proviral latency (GO:0075713)3.44232709
45nuclear envelope disassembly (GO:0051081)3.44082354
46membrane disassembly (GO:0030397)3.44082354
47mitotic spindle organization (GO:0007052)3.42915122
48negative regulation of DNA-dependent DNA replication (GO:2000104)3.37443779
49spindle checkpoint (GO:0031577)3.35671584
50positive regulation of chromosome segregation (GO:0051984)3.33104182
51protein K6-linked ubiquitination (GO:0085020)3.32910091
52IMP metabolic process (GO:0046040)3.31407582
53IMP biosynthetic process (GO:0006188)3.29851812
54kinetochore assembly (GO:0051382)3.29448533
55DNA replication-dependent nucleosome organization (GO:0034723)3.26577451
56DNA replication-dependent nucleosome assembly (GO:0006335)3.26577451
57telomere maintenance via telomere lengthening (GO:0010833)3.23855671
58regulation of chromosome segregation (GO:0051983)3.22863113
59protein localization to chromosome (GO:0034502)3.20090496
60sister chromatid cohesion (GO:0007062)3.18801805
61chromosome segregation (GO:0007059)3.18049440
62regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.14666090
63nucleotide-excision repair, DNA gap filling (GO:0006297)3.14515487
64regulation of meiosis I (GO:0060631)3.12142642
65spindle assembly checkpoint (GO:0071173)3.11441103
66mitotic sister chromatid cohesion (GO:0007064)3.09396743
67replication fork processing (GO:0031297)3.08898683
68mitotic spindle checkpoint (GO:0071174)3.08886190
69negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.07949763
70negative regulation of sister chromatid segregation (GO:0033046)3.07949763
71negative regulation of mitotic sister chromatid separation (GO:2000816)3.07949763
72negative regulation of mitotic sister chromatid segregation (GO:0033048)3.07949763
73negative regulation of chromosome segregation (GO:0051985)3.06517538
74regulation of mitotic metaphase/anaphase transition (GO:0030071)3.06082819
75folic acid-containing compound biosynthetic process (GO:0009396)3.06060367
76mitotic spindle assembly checkpoint (GO:0007094)3.04773390
77negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.03903474
78regulation of sister chromatid cohesion (GO:0007063)3.03072516
79regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.02998572
80regulation of centrosome cycle (GO:0046605)2.99333242
81maturation of 5.8S rRNA (GO:0000460)2.98856824
82spindle assembly involved in mitosis (GO:0090307)2.98233622
83histone-serine phosphorylation (GO:0035404)2.98222067
84postreplication repair (GO:0006301)2.97168686
85negative regulation of DNA recombination (GO:0045910)2.93441293
86chromatin assembly or disassembly (GO:0006333)2.91755939
87ribosomal small subunit assembly (GO:0000028)2.91430892
88positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.91228378
89positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.91228378
90positive regulation of mitotic sister chromatid separation (GO:1901970)2.91228378
91histone H2A acetylation (GO:0043968)2.88968601
92regulation of sister chromatid segregation (GO:0033045)2.87658023
93regulation of mitotic sister chromatid separation (GO:0010965)2.87658023
94regulation of mitotic sister chromatid segregation (GO:0033047)2.87658023
95chromosome condensation (GO:0030261)2.83678734
96regulation of double-strand break repair via homologous recombination (GO:0010569)2.82184288
97telomere maintenance (GO:0000723)2.78122509
98telomere organization (GO:0032200)2.77285680
99mismatch repair (GO:0006298)2.77226777
100pore complex assembly (GO:0046931)2.72210828
101DNA topological change (GO:0006265)2.69682303
102monoubiquitinated protein deubiquitination (GO:0035520)2.69177474
103nuclear envelope organization (GO:0006998)2.66560334
104ATP-dependent chromatin remodeling (GO:0043044)2.65579310
105* mitotic cell cycle (GO:0000278)2.64784366
106DNA-dependent DNA replication (GO:0006261)2.63826693
107ribosome assembly (GO:0042255)2.63312080
108mitotic G2/M transition checkpoint (GO:0044818)2.62967768
109DNA duplex unwinding (GO:0032508)2.59296521
110DNA geometric change (GO:0032392)2.59184480
111DNA packaging (GO:0006323)2.56634386
112DNA conformation change (GO:0071103)2.52566688
113base-excision repair (GO:0006284)2.50846353
114anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.50047949
115mitotic G2 DNA damage checkpoint (GO:0007095)2.48585022
116histone H2A monoubiquitination (GO:0035518)2.48416062
117cell cycle G1/S phase transition (GO:0044843)2.45595410
118G1/S transition of mitotic cell cycle (GO:0000082)2.45595410
119negative regulation of mitosis (GO:0045839)2.45579974
120formation of translation preinitiation complex (GO:0001731)2.44828636

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.04323360
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.08124467
3* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.03403143
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.65631872
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.22989360
6AR_21909140_ChIP-Seq_LNCAP_Human2.79836788
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.72727436
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.71495387
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.57780090
10* GABP_17652178_ChIP-ChIP_JURKAT_Human2.42825914
11CREB1_15753290_ChIP-ChIP_HEK293T_Human2.35148129
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.21381916
13NELFA_20434984_ChIP-Seq_ESCs_Mouse2.16216500
14E2F1_21310950_ChIP-Seq_MCF-7_Human2.14632255
15MYC_18358816_ChIP-ChIP_MESCs_Mouse2.08425923
16MYC_19079543_ChIP-ChIP_MESCs_Mouse2.01624720
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.00574301
18VDR_23849224_ChIP-Seq_CD4+_Human1.97284116
19* EWS_26573619_Chip-Seq_HEK293_Human1.95148106
20MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.94481708
21ETS1_20019798_ChIP-Seq_JURKAT_Human1.90936819
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.89914717
23EGR1_19374776_ChIP-ChIP_THP-1_Human1.89826308
24SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.87315689
25PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.84652076
26MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.80332750
27KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.79569863
28ELF1_17652178_ChIP-ChIP_JURKAT_Human1.79527065
29POU3F2_20337985_ChIP-ChIP_501MEL_Human1.78086097
30ELK1_19687146_ChIP-ChIP_HELA_Human1.77040867
31FOXP3_21729870_ChIP-Seq_TREG_Human1.75327594
32HOXB4_20404135_ChIP-ChIP_EML_Mouse1.73642703
33XRN2_22483619_ChIP-Seq_HELA_Human1.73277048
34FUS_26573619_Chip-Seq_HEK293_Human1.67336829
35E2F1_18555785_ChIP-Seq_MESCs_Mouse1.64503557
36DCP1A_22483619_ChIP-Seq_HELA_Human1.64426638
37HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.63496940
38MYCN_18555785_ChIP-Seq_MESCs_Mouse1.62243165
39FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.61429490
40MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.56821257
41IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.52205562
42* GABP_19822575_ChIP-Seq_HepG2_Human1.51884269
43ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.49993430
44CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.48855839
45SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.45471978
46NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.43022333
47TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.42686687
48FLI1_27457419_Chip-Seq_LIVER_Mouse1.41221259
49FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.40787533
50VDR_22108803_ChIP-Seq_LS180_Human1.39800504
51IRF8_21731497_ChIP-ChIP_J774_Mouse1.39025088
52ZNF274_21170338_ChIP-Seq_K562_Hela1.38419131
53ERG_20887958_ChIP-Seq_HPC-7_Mouse1.37623671
54SRF_21415370_ChIP-Seq_HL-1_Mouse1.37020768
55HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.37008473
56BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.36533228
57TTF2_22483619_ChIP-Seq_HELA_Human1.34908917
58NANOG_18555785_ChIP-Seq_MESCs_Mouse1.33864973
59SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.33095549
60WT1_19549856_ChIP-ChIP_CCG9911_Human1.32207406
61CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.31180341
62TAF15_26573619_Chip-Seq_HEK293_Human1.29965681
63FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.29903869
64SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.29610344
65KDM5A_27292631_Chip-Seq_BREAST_Human1.29031767
66HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.29028858
67* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.27697138
68YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26940824
69PADI4_21655091_ChIP-ChIP_MCF-7_Human1.26181966
70CIITA_25753668_ChIP-Seq_RAJI_Human1.25076606
71HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.24451329
72IRF8_22096565_ChIP-ChIP_GC-B_Human1.23734931
73MYC_22102868_ChIP-Seq_BL_Human1.22199166
74* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.22113175
75PCGF2_27294783_Chip-Seq_ESCs_Mouse1.21833530
76RBPJ_22232070_ChIP-Seq_NCS_Mouse1.20266318
77POU5F1_16153702_ChIP-ChIP_HESCs_Human1.20222584
78SPI1_23547873_ChIP-Seq_NB4_Human1.19416456
79POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.18257851
80NANOG_16153702_ChIP-ChIP_HESCs_Human1.17716948
81RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.13188217
82GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12816752
83MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.11719616
84* EZH2_27294783_Chip-Seq_NPCs_Mouse1.11211786
85TFEB_21752829_ChIP-Seq_HELA_Human1.10503792
86MYB_21317192_ChIP-Seq_ERMYB_Mouse1.09514969
87* P300_19829295_ChIP-Seq_ESCs_Human1.07057219
88TP63_19390658_ChIP-ChIP_HaCaT_Human1.05764044
89NOTCH1_21737748_ChIP-Seq_TLL_Human1.05581431
90SALL1_21062744_ChIP-ChIP_HESCs_Human1.03024036
91KLF4_18555785_ChIP-Seq_MESCs_Mouse1.02197739
92TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.01051481
93CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.00987604
94E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.00320066
95CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.99725791
96SOX17_20123909_ChIP-Seq_XEN_Mouse0.99314712
97GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.96363387
98SOX2_16153702_ChIP-ChIP_HESCs_Human0.94865354
99SUZ12_27294783_Chip-Seq_NPCs_Mouse0.94100272
100SOX2_18555785_ChIP-Seq_MESCs_Mouse0.93763977
101FOXM1_26456572_ChIP-Seq_MCF-7_Human0.93429222
102POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.93354030
103MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.92776478
104PCGF2_27294783_Chip-Seq_NPCs_Mouse0.92739587
105EGR1_23403033_ChIP-Seq_LIVER_Mouse0.92498488
106SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.92405502
107IGF1R_20145208_ChIP-Seq_DFB_Human0.92276696
108MYB_26560356_Chip-Seq_TH2_Human0.90657786
109* ZFP57_27257070_Chip-Seq_ESCs_Mouse0.88542402
110MYC_18940864_ChIP-ChIP_HL60_Human0.88473828
111CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.88348300
112MYB_26560356_Chip-Seq_TH1_Human0.87792758
113ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.87698224
114NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.86979478
115SMAD_19615063_ChIP-ChIP_OVARY_Human0.86753130
116SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.86167499
117STAT3_1855785_ChIP-Seq_MESCs_Mouse0.86164710
118KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.85288579
119KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.85288579
120KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.85288579
121ER_23166858_ChIP-Seq_MCF-7_Human0.84686682
122NFE2_27457419_Chip-Seq_LIVER_Mouse0.83902576
123* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.83482934
124ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.83411594
125AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.83185146
126GATA2_22383799_ChIP-Seq_G1ME_Mouse0.82777207
127TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.82748950
128* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.81880534
129THAP11_20581084_ChIP-Seq_MESCs_Mouse0.80090686
130HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.79651317
131* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.79468753
132STAT4_19710469_ChIP-ChIP_TH1__Mouse0.79235293
133* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.79156733
134PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.78915550
135FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.78599548
136BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.77925782
137NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.77278254
138VDR_21846776_ChIP-Seq_THP-1_Human0.74725499
139STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.74601417
140GATA1_22383799_ChIP-Seq_G1ME_Mouse0.74020026
141CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.73692471

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.13815540
2MP0010094_abnormal_chromosome_stability3.87570449
3MP0003111_abnormal_nucleus_morphology3.35506394
4MP0003077_abnormal_cell_cycle3.25805370
5MP0004957_abnormal_blastocyst_morpholog3.05981929
6MP0008057_abnormal_DNA_replication3.01860595
7MP0003890_abnormal_embryonic-extraembry2.58117949
8MP0008007_abnormal_cellular_replicative2.48934035
9MP0002396_abnormal_hematopoietic_system2.36396413
10MP0008058_abnormal_DNA_repair2.26859878
11MP0003941_abnormal_skin_development1.92034140
12MP0008932_abnormal_embryonic_tissue1.86194314
13MP0003718_maternal_effect1.78836611
14MP0001293_anophthalmia1.73573684
15MP0010352_gastrointestinal_tract_polyps1.72451710
16MP0010234_abnormal_vibrissa_follicle1.70796099
17MP0008877_abnormal_DNA_methylation1.64413124
18MP0001730_embryonic_growth_arrest1.59652932
19MP0000350_abnormal_cell_proliferation1.59552774
20MP0004808_abnormal_hematopoietic_stem1.56211717
21MP0010307_abnormal_tumor_latency1.55299701
22MP0009333_abnormal_splenocyte_physiolog1.53608957
23MP0010030_abnormal_orbit_morphology1.50601301
24MP0001545_abnormal_hematopoietic_system1.50282084
25MP0005397_hematopoietic_system_phenotyp1.50282084
26MP0003763_abnormal_thymus_physiology1.49362473
27MP0000490_abnormal_crypts_of1.43402411
28MP0000749_muscle_degeneration1.41992414
29MP0001835_abnormal_antigen_presentation1.41143991
30MP0003646_muscle_fatigue1.38286659
31MP0003786_premature_aging1.37196933
32MP0003950_abnormal_plasma_membrane1.36572693
33MP0004147_increased_porphyrin_level1.32082397
34MP0001672_abnormal_embryogenesis/_devel1.28513863
35MP0005380_embryogenesis_phenotype1.28513863
36MP0002019_abnormal_tumor_incidence1.28048929
37MP0002009_preneoplasia1.28028396
38MP0001853_heart_inflammation1.27804652
39MP0003806_abnormal_nucleotide_metabolis1.27499038
40MP0003123_paternal_imprinting1.27322638
41MP0008789_abnormal_olfactory_epithelium1.26658391
42MP0009697_abnormal_copulation1.25720286
43MP0005360_urolithiasis1.23484880
44MP0001697_abnormal_embryo_size1.23409084
45MP0003705_abnormal_hypodermis_morpholog1.23308368
46MP0001286_abnormal_eye_development1.22619675
47MP0003567_abnormal_fetal_cardiomyocyte1.22547429
48MP0002398_abnormal_bone_marrow1.21391141
49MP0009785_altered_susceptibility_to1.19866563
50MP0003984_embryonic_growth_retardation1.17529881
51MP0004233_abnormal_muscle_weight1.17213530
52MP0006054_spinal_hemorrhage1.16449067
53MP0000689_abnormal_spleen_morphology1.16243954
54MP0001915_intracranial_hemorrhage1.15395404
55MP0002088_abnormal_embryonic_growth/wei1.14553516
56MP0010678_abnormal_skin_adnexa1.13574295
57MP0002722_abnormal_immune_system1.12705232
58MP0002233_abnormal_nose_morphology1.11419188
59MP0005671_abnormal_response_to1.10795246
60MP0006072_abnormal_retinal_apoptosis1.10543359
61MP0000313_abnormal_cell_death1.09867938
62MP0006292_abnormal_olfactory_placode1.08876419
63MP0002080_prenatal_lethality1.08411480
64MP0000427_abnormal_hair_cycle1.08022650
65MP0000685_abnormal_immune_system1.06747462
66MP0002086_abnormal_extraembryonic_tissu1.06312725
67MP0002877_abnormal_melanocyte_morpholog1.06117515
68MP0000428_abnormal_craniofacial_morphol1.05796025
69MP0003186_abnormal_redox_activity1.05651315
70MP0005408_hypopigmentation1.04634135
71MP0002938_white_spotting1.04243407
72MP0000537_abnormal_urethra_morphology1.03338553
73MP0000647_abnormal_sebaceous_gland1.02496170
74MP0002697_abnormal_eye_size1.01993380
75MP0000751_myopathy1.01577598
76MP0001119_abnormal_female_reproductive1.01455172
77MP0001800_abnormal_humoral_immune1.01138078
78MP0004145_abnormal_muscle_electrophysio0.99703191
79MP0004084_abnormal_cardiac_muscle0.99237674
80MP0002085_abnormal_embryonic_tissue0.98341853
81MP0002429_abnormal_blood_cell0.98337399
82MP0002102_abnormal_ear_morphology0.97890847
83MP0002405_respiratory_system_inflammati0.97723371
84MP0002452_abnormal_antigen_presenting0.97641472
85MP0002132_abnormal_respiratory_system0.95892216
86MP0002269_muscular_atrophy0.94953319
87MP0010155_abnormal_intestine_physiology0.94903250
88MP0005451_abnormal_body_composition0.94388119
89MP0009672_abnormal_birth_weight0.93551270
90MP0000716_abnormal_immune_system0.93336216
91MP0005023_abnormal_wound_healing0.93282325
92MP0000703_abnormal_thymus_morphology0.93259863
93MP0000358_abnormal_cell_content/0.92334452
94MP0002210_abnormal_sex_determination0.91542967
95MP0003136_yellow_coat_color0.91288412
96MP0003755_abnormal_palate_morphology0.90391013
97MP0003656_abnormal_erythrocyte_physiolo0.90173150
98MP0005248_abnormal_Harderian_gland0.89586931
99MP0010368_abnormal_lymphatic_system0.88842175
100MP0002420_abnormal_adaptive_immunity0.88573502
101MP0003436_decreased_susceptibility_to0.87889262
102MP0001819_abnormal_immune_cell0.87584870
103MP0005395_other_phenotype0.87102984
104MP0002419_abnormal_innate_immunity0.86454814
105MP0000383_abnormal_hair_follicle0.84677389
106MP0009278_abnormal_bone_marrow0.84446076
107MP0002723_abnormal_immune_serum0.83365119
108MP0002084_abnormal_developmental_patter0.83301815
109MP0002166_altered_tumor_susceptibility0.82836406
110MP0002006_tumorigenesis0.82518606
111MP0002111_abnormal_tail_morphology0.81892363
112MP0003121_genomic_imprinting0.81518518
113MP0005025_abnormal_response_to0.81387358
114MP0003191_abnormal_cellular_cholesterol0.81351205
115MP0000372_irregular_coat_pigmentation0.80448361
116MP0009703_decreased_birth_body0.79916259
117MP0002092_abnormal_eye_morphology0.79844328
118MP0001929_abnormal_gametogenesis0.79794884
119MP0001346_abnormal_lacrimal_gland0.79730503
120MP0003221_abnormal_cardiomyocyte_apopto0.79715992
121MP0004215_abnormal_myocardial_fiber0.79009972
122MP0002234_abnormal_pharynx_morphology0.78503862
123MP0005000_abnormal_immune_tolerance0.78377011
124MP0000569_abnormal_digit_pigmentation0.78073448
125MP0000858_altered_metastatic_potential0.77291222
126MP0005464_abnormal_platelet_physiology0.77266387
127MP0004197_abnormal_fetal_growth/weight/0.76873028
128MP0003935_abnormal_craniofacial_develop0.76181379
129MP0000653_abnormal_sex_gland0.75532370
130MP0000762_abnormal_tongue_morphology0.75174741
131MP0003119_abnormal_digestive_system0.73111633
132MP0001873_stomach_inflammation0.72952941
133MP0003943_abnormal_hepatobiliary_system0.72198973
134MP0000598_abnormal_liver_morphology0.72042629
135MP0000613_abnormal_salivary_gland0.71017979
136MP0000465_gastrointestinal_hemorrhage0.70961976
137MP0001145_abnormal_male_reproductive0.70831012
138MP0000432_abnormal_head_morphology0.70638520
139MP0005076_abnormal_cell_differentiation0.70392866
140MP0009840_abnormal_foam_cell0.70247471
141MP0002148_abnormal_hypersensitivity_rea0.69634320
142MP0003385_abnormal_body_wall0.69061257
143MP0005394_taste/olfaction_phenotype0.68822881
144MP0005499_abnormal_olfactory_system0.68822881
145MP0000733_abnormal_muscle_development0.68784151
146MP0003698_abnormal_male_reproductive0.68435932
147MP0003937_abnormal_limbs/digits/tail_de0.68232561
148MP0003699_abnormal_female_reproductive0.67776587
149MP0003828_pulmonary_edema0.67598561
150MP0005391_vision/eye_phenotype0.67119720
151MP0006035_abnormal_mitochondrial_morpho0.65715975
152MP0003448_altered_tumor_morphology0.65263391
153MP0005187_abnormal_penis_morphology0.63795972
154MP0004272_abnormal_basement_membrane0.63587985

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.39890961
2Birth length less than 3rd percentile (HP:0003561)4.28394274
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.08347215
4Abnormality of the labia minora (HP:0012880)3.84404617
5Volvulus (HP:0002580)3.70292463
6Abnormality of chromosome stability (HP:0003220)3.41418688
7Nemaline bodies (HP:0003798)3.13264471
8Breast hypoplasia (HP:0003187)2.99034614
9Muscle fiber inclusion bodies (HP:0100299)2.95868749
10Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.88657409
11Papillary thyroid carcinoma (HP:0002895)2.81944091
12Increased nuchal translucency (HP:0010880)2.80075164
13Meckel diverticulum (HP:0002245)2.75733289
14Thrombocytosis (HP:0001894)2.72863266
15Reticulocytopenia (HP:0001896)2.70325653
16Patellar aplasia (HP:0006443)2.67896759
17Abnormality of the preputium (HP:0100587)2.66919289
18Colon cancer (HP:0003003)2.66629109
19Aplasia/Hypoplasia of the uvula (HP:0010293)2.61373787
20Selective tooth agenesis (HP:0001592)2.61295060
21Ectopic kidney (HP:0000086)2.59752284
22Abnormality of the ileum (HP:0001549)2.54164560
23Myelodysplasia (HP:0002863)2.53709109
24Abnormal auditory evoked potentials (HP:0006958)2.53325761
25Acute myeloid leukemia (HP:0004808)2.52333383
26Abnormality of the ischium (HP:0003174)2.49643641
27Exercise-induced muscle cramps (HP:0003710)2.47005461
28Aplasia/Hypoplasia of the patella (HP:0006498)2.46087312
29Degeneration of anterior horn cells (HP:0002398)2.44436523
30Abnormality of the anterior horn cell (HP:0006802)2.44436523
31Oral leukoplakia (HP:0002745)2.44068577
32Aplastic anemia (HP:0001915)2.38899412
33Type I transferrin isoform profile (HP:0003642)2.38748193
34Abnormality of pyrimidine metabolism (HP:0004353)2.38471058
35Abnormal lung lobation (HP:0002101)2.33808887
36Cystic hygroma (HP:0000476)2.28652145
37Small intestinal stenosis (HP:0012848)2.28071791
38Duodenal stenosis (HP:0100867)2.28071791
39Impulsivity (HP:0100710)2.25892329
4011 pairs of ribs (HP:0000878)2.25698584
41Bone marrow hypocellularity (HP:0005528)2.22866819
42Medulloblastoma (HP:0002885)2.22179274
43Abnormal spermatogenesis (HP:0008669)2.21323794
44Hypoplastic ischia (HP:0003175)2.20650873
45Ovarian neoplasm (HP:0100615)2.16408582
46Pulmonary fibrosis (HP:0002206)2.16348646
47Sloping forehead (HP:0000340)2.16324718
48Agnosia (HP:0010524)2.16313438
49Cutaneous melanoma (HP:0012056)2.15595519
50Neoplasm of the colon (HP:0100273)2.13897984
51Oligodactyly (hands) (HP:0001180)2.13299867
52Intestinal atresia (HP:0011100)2.11653826
53Pustule (HP:0200039)2.11400894
54Gonadotropin excess (HP:0000837)2.09812830
55Abnormality of DNA repair (HP:0003254)2.08089309
56Thyroid carcinoma (HP:0002890)2.08079306
57Clubbing of toes (HP:0100760)2.05505025
58Supernumerary spleens (HP:0009799)2.02240625
59Neoplasm of the oral cavity (HP:0100649)2.02060606
60Microglossia (HP:0000171)1.99996497
61Abnormal number of erythroid precursors (HP:0012131)1.99098320
62Short 4th metacarpal (HP:0010044)1.97618343
63Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.97618343
64Embryonal neoplasm (HP:0002898)1.97095794
65Triphalangeal thumb (HP:0001199)1.96440425
66Lymphoma (HP:0002665)1.96279619
67Gastrointestinal atresia (HP:0002589)1.95859735
68Osteolytic defects of the phalanges of the hand (HP:0009771)1.94403261
69Osteolytic defects of the hand bones (HP:0009699)1.94403261
70Amaurosis fugax (HP:0100576)1.93657999
71Abnormality of the prostate (HP:0008775)1.93598412
72Squamous cell carcinoma (HP:0002860)1.93531217
73Nonimmune hydrops fetalis (HP:0001790)1.92160285
74Multiple enchondromatosis (HP:0005701)1.91951100
75Short tibia (HP:0005736)1.90693574
76Abnormality of cells of the erythroid lineage (HP:0012130)1.90368549
77Abnormal protein glycosylation (HP:0012346)1.90308741
78Abnormal glycosylation (HP:0012345)1.90308741
79Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.90308741
80Abnormal protein N-linked glycosylation (HP:0012347)1.90308741
81Rimmed vacuoles (HP:0003805)1.89698561
82Abnormality of the fingertips (HP:0001211)1.89226755
83Duplicated collecting system (HP:0000081)1.89143067
84Microretrognathia (HP:0000308)1.88885127
85Blepharitis (HP:0000498)1.88824860
86Absent radius (HP:0003974)1.86796412
87Entropion (HP:0000621)1.86732133
88Microvesicular hepatic steatosis (HP:0001414)1.86115113
89Abnormality of the duodenum (HP:0002246)1.86051885
90High pitched voice (HP:0001620)1.84969218
91Abnormality of the calcaneus (HP:0008364)1.84474794
92Methylmalonic acidemia (HP:0002912)1.81552841
93Choanal atresia (HP:0000453)1.79431705
94Nausea (HP:0002018)1.78957355
95Recurrent abscess formation (HP:0002722)1.78486544
96Abnormality of methionine metabolism (HP:0010901)1.77442786
97Autoimmune thrombocytopenia (HP:0001973)1.76205671
98Neoplasm of the adrenal gland (HP:0100631)1.76112655
99Rough bone trabeculation (HP:0100670)1.75734269
100Combined immunodeficiency (HP:0005387)1.75347845
101Abnormality of the pons (HP:0007361)1.73191346
102IgM deficiency (HP:0002850)1.73035165
103Abnormal platelet volume (HP:0011876)1.71772614
104Clitoromegaly (HP:0000057)1.71771902
105Abnormality of chromosome segregation (HP:0002916)1.71033633
106Aplasia/Hypoplasia of the tibia (HP:0005772)1.70184588
107Cellular immunodeficiency (HP:0005374)1.69810922
108Short thumb (HP:0009778)1.69667645
109Increased mean platelet volume (HP:0011877)1.69248592
110Hypoplasia of the pons (HP:0012110)1.68695718
111Abnormality of the renal collecting system (HP:0004742)1.68364215
112Absent forearm bone (HP:0003953)1.68048286
113Aplasia involving forearm bones (HP:0009822)1.68048286
114Facial hemangioma (HP:0000329)1.67725068
115Abnormality of the carotid arteries (HP:0005344)1.67436845
116Abnormality of T cells (HP:0002843)1.67120115
117Glioma (HP:0009733)1.67051319
118Transitional cell carcinoma of the bladder (HP:0006740)1.67025762
119Shoulder girdle muscle weakness (HP:0003547)1.66441542
120Neoplasm of the pancreas (HP:0002894)1.66193791
121Cleft eyelid (HP:0000625)1.65963484
122Cafe-au-lait spot (HP:0000957)1.65878823
123Premature graying of hair (HP:0002216)1.65799376
124Nephroblastoma (Wilms tumor) (HP:0002667)1.65755459
125Arteriovenous malformation (HP:0100026)1.64378420
126Biliary tract neoplasm (HP:0100574)1.63954519
127Abnormality of T cell physiology (HP:0011840)1.63501854
128Recurrent viral infections (HP:0004429)1.63492184
129Secondary amenorrhea (HP:0000869)1.63048684
130IgG deficiency (HP:0004315)1.62684565
131Stillbirth (HP:0003826)1.61660189
132Breast carcinoma (HP:0003002)1.61557198
133Reduced subcutaneous adipose tissue (HP:0003758)1.61378035
134Embryonal renal neoplasm (HP:0011794)1.61319519
135Ankle contracture (HP:0006466)1.61264035
136Median cleft lip (HP:0000161)1.61219650
137Abnormality of the heme biosynthetic pathway (HP:0010472)1.60844580
138Abnormality of the septum pellucidum (HP:0007375)1.60537855
139Carpal bone hypoplasia (HP:0001498)1.60237830
140Capillary hemangiomas (HP:0005306)1.60237547
141Uterine leiomyosarcoma (HP:0002891)1.60094621
142Leiomyosarcoma (HP:0100243)1.60094621
143Long clavicles (HP:0000890)1.59742667
144Glucose intolerance (HP:0000833)1.59665510
145Abnormality of placental membranes (HP:0011409)1.59564035
146Amniotic constriction ring (HP:0009775)1.59564035
147Pancytopenia (HP:0001876)1.59247389
148Abnormality of the left ventricular outflow tract (HP:0011103)1.59234716
149Subaortic stenosis (HP:0001682)1.59234716
150Rhabdomyosarcoma (HP:0002859)1.58959451
151Aplasia/Hypoplasia of the sternum (HP:0006714)1.58325459
152Abnormality of the musculature of the pelvis (HP:0001469)1.57709080
153Abnormality of the hip-girdle musculature (HP:0001445)1.57709080
154Neoplasm of the small intestine (HP:0100833)1.57626359
155Prominent nose (HP:0000448)1.57597389
156Abnormality of the lower motor neuron (HP:0002366)1.57332186
157Hyperglycinemia (HP:0002154)1.56180231
158Deep philtrum (HP:0002002)1.55534438
159Slender long bone (HP:0003100)1.55450416
160Leukopenia (HP:0001882)1.54799209
161Reduced antithrombin III activity (HP:0001976)1.54743204
162Esophageal atresia (HP:0002032)1.54556801
163Ureteral duplication (HP:0000073)1.54363961

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC73.66818538
2WEE13.53760552
3BUB13.32527884
4PLK42.64839237
5ACVR1B2.60861823
6EIF2AK12.60386172
7NEK22.59810735
8BRSK22.54287764
9MST42.47837621
10TTK2.43649417
11TRIM282.38869146
12PNCK2.12655648
13BCR2.07677615
14STK102.04827848
15OBSCN1.98375914
16ERBB31.80257586
17* PLK11.80173537
18MKNK11.77832714
19STK31.77493335
20AURKB1.72068986
21EEF2K1.69859408
22TAF11.68269569
23SRPK11.64877958
24RPS6KA41.54924353
25PASK1.51650829
26LATS11.49889635
27EIF2AK31.43785436
28STK41.42323342
29NEK11.40475519
30TGFBR11.39408422
31BRD41.37297505
32PLK31.36220926
33MKNK21.35335818
34MAP4K11.34403071
35ZAK1.34058654
36VRK11.33743487
37TNIK1.33283968
38MAP3K81.32781759
39ATR1.31179644
40BRSK11.30968331
41CDK41.28352521
42NME21.25243930
43CHEK21.24995905
44MELK1.24367887
45STK38L1.22984486
46RPS6KB21.16977638
47PLK21.11618731
48PIM11.11500426
49JAK31.11121329
50SCYL21.09750856
51CDK81.08532094
52CDK71.06807990
53FLT31.03392027
54CHEK11.01859226
55TAOK31.01058858
56CCNB11.00279374
57MAP3K130.98830245
58PKN20.98022916
59BMPR1B0.97667331
60DYRK30.96448234
61STK160.96431413
62CLK10.94923587
63VRK20.93090897
64IRAK40.92594445
65YES10.91855937
66NUAK10.89721973
67TYK20.88564063
68TXK0.88437244
69MET0.88152586
70TSSK60.87573153
71KIT0.87546317
72EIF2AK20.87016116
73MARK30.86705375
74CDK60.86033792
75TEC0.84080119
76CDK90.81739747
77TESK20.81456638
78ATM0.79423293
79WNK30.79116415
80TLK10.78211700
81MAP3K90.78108594
82MAP3K140.76880640
83STK390.76252195
84TRPM70.75610994
85IRAK30.74972496
86PBK0.74579294
87AURKA0.74287306
88LRRK20.72485820
89NLK0.71667066
90SIK30.70434972
91PIM20.68836562
92PIK3CA0.68315837
93KDR0.67393381
94BRAF0.65687047
95TTN0.65036871
96KSR10.64138927
97ERBB40.63558314
98CHUK0.63352088
99CSNK1G10.63308762
100PAK40.60286036
101BTK0.60120026
102IKBKB0.57589026
103MAPK110.56365589
104NEK60.56082661
105STK240.55678106
106CDK120.53665126
107MAP2K30.53510961
108CDK20.52605040
109MUSK0.51875055
110MAP3K40.50903899
111MAPKAPK30.50666624
112FGFR10.50543759
113BLK0.50429166
114ZAP700.48613964
115CSNK2A10.47899908
116MAP3K100.46068053
117CSNK1G30.45411346
118* CDK10.45152660
119MOS0.44718696
120CDK30.44693448
121RPS6KA50.44666255
122FRK0.44383613
123PIK3CG0.43961833
124FGFR20.43259016
125CSNK1G20.42885284
126TIE10.41105054
127MAP3K120.39768688
128CSF1R0.38490886
129CSNK1A1L0.37298085
130RAF10.37145990
131EPHA20.36903316
132DMPK0.36819986
133ABL20.36445631
134NME10.32648392
135PRKDC0.30047552
136CSNK2A20.28826755
137RPS6KB10.26278737
138CSNK1E0.25972773
139MST1R0.24078747
140PHKG20.21346601

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.41029763
2Mismatch repair_Homo sapiens_hsa034303.59818035
3Cell cycle_Homo sapiens_hsa041103.02345339
4Base excision repair_Homo sapiens_hsa034103.00138505
5Homologous recombination_Homo sapiens_hsa034402.90649691
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.69727004
7Nucleotide excision repair_Homo sapiens_hsa034202.45803067
8RNA transport_Homo sapiens_hsa030132.42599074
9One carbon pool by folate_Homo sapiens_hsa006702.33577526
10RNA polymerase_Homo sapiens_hsa030202.28794031
11Spliceosome_Homo sapiens_hsa030402.22465586
12Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.19667925
13Vitamin B6 metabolism_Homo sapiens_hsa007502.19656023
14Fanconi anemia pathway_Homo sapiens_hsa034602.17973448
15Proteasome_Homo sapiens_hsa030502.06198814
16Pyrimidine metabolism_Homo sapiens_hsa002402.01487183
17RNA degradation_Homo sapiens_hsa030181.97183416
18Non-homologous end-joining_Homo sapiens_hsa034501.95657112
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.89565096
20p53 signaling pathway_Homo sapiens_hsa041151.87806269
21Basal transcription factors_Homo sapiens_hsa030221.87766055
22Ribosome_Homo sapiens_hsa030101.65512579
23Steroid biosynthesis_Homo sapiens_hsa001001.63123584
24Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.43534866
25Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.38463454
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.21961142
27Folate biosynthesis_Homo sapiens_hsa007901.19320575
28Herpes simplex infection_Homo sapiens_hsa051681.18376908
29Antigen processing and presentation_Homo sapiens_hsa046121.14116473
30Systemic lupus erythematosus_Homo sapiens_hsa053221.11380551
31NF-kappa B signaling pathway_Homo sapiens_hsa040641.09577028
32Pyruvate metabolism_Homo sapiens_hsa006201.09261612
33Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.08694675
34Purine metabolism_Homo sapiens_hsa002301.08395892
35mRNA surveillance pathway_Homo sapiens_hsa030151.08359441
36Selenocompound metabolism_Homo sapiens_hsa004501.07952307
37Epstein-Barr virus infection_Homo sapiens_hsa051691.06402033
38Drug metabolism - other enzymes_Homo sapiens_hsa009831.05646116
39Adherens junction_Homo sapiens_hsa045200.99154596
40Small cell lung cancer_Homo sapiens_hsa052220.98756211
41Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.97227046
42Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.95624362
43Viral carcinogenesis_Homo sapiens_hsa052030.95318741
44Pentose phosphate pathway_Homo sapiens_hsa000300.89523662
45Cysteine and methionine metabolism_Homo sapiens_hsa002700.87190767
46Biosynthesis of amino acids_Homo sapiens_hsa012300.83215181
47Measles_Homo sapiens_hsa051620.83205436
48Fatty acid elongation_Homo sapiens_hsa000620.83073117
49Circadian rhythm_Homo sapiens_hsa047100.81607747
50HTLV-I infection_Homo sapiens_hsa051660.80383211
51Legionellosis_Homo sapiens_hsa051340.77180576
52Hippo signaling pathway_Homo sapiens_hsa043900.76923973
53Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.75261412
54Basal cell carcinoma_Homo sapiens_hsa052170.74573685
55Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.74350512
56Intestinal immune network for IgA production_Homo sapiens_hsa046720.73845081
57Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.72670014
58Apoptosis_Homo sapiens_hsa042100.71078173
59Wnt signaling pathway_Homo sapiens_hsa043100.70552632
60Primary immunodeficiency_Homo sapiens_hsa053400.70074216
61MicroRNAs in cancer_Homo sapiens_hsa052060.70065273
62N-Glycan biosynthesis_Homo sapiens_hsa005100.68688209
63Hedgehog signaling pathway_Homo sapiens_hsa043400.66153058
64Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.65897528
65Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.60984275
66Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.60842010
67Transcriptional misregulation in cancer_Homo sapiens_hsa052020.60021920
68Protein export_Homo sapiens_hsa030600.58478461
69Oocyte meiosis_Homo sapiens_hsa041140.58033210
70Glutathione metabolism_Homo sapiens_hsa004800.57226538
71Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.57159798
72Leishmaniasis_Homo sapiens_hsa051400.55989841
73Hepatitis B_Homo sapiens_hsa051610.55298618
74Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.55277230
75Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.55111730
76Hematopoietic cell lineage_Homo sapiens_hsa046400.54877910
77Influenza A_Homo sapiens_hsa051640.54510204
78Sulfur relay system_Homo sapiens_hsa041220.54386733
79Viral myocarditis_Homo sapiens_hsa054160.54341580
80Carbon metabolism_Homo sapiens_hsa012000.54280446
81NOD-like receptor signaling pathway_Homo sapiens_hsa046210.53612228
82Staphylococcus aureus infection_Homo sapiens_hsa051500.52310976
83TGF-beta signaling pathway_Homo sapiens_hsa043500.51578258
84Thyroid cancer_Homo sapiens_hsa052160.50878716
85Pancreatic cancer_Homo sapiens_hsa052120.50492609
86Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.49660658
87Jak-STAT signaling pathway_Homo sapiens_hsa046300.47370490
88Lysine degradation_Homo sapiens_hsa003100.46781990
89Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.44257105
90Toxoplasmosis_Homo sapiens_hsa051450.43750783
91Chronic myeloid leukemia_Homo sapiens_hsa052200.43514165
92Tight junction_Homo sapiens_hsa045300.42450890
93Huntingtons disease_Homo sapiens_hsa050160.42245769
94Shigellosis_Homo sapiens_hsa051310.41992942
95Allograft rejection_Homo sapiens_hsa053300.40608997
96Malaria_Homo sapiens_hsa051440.40008306
97Complement and coagulation cascades_Homo sapiens_hsa046100.38901292
98RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.38487342
99Alcoholism_Homo sapiens_hsa050340.38072216
100Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37570350
101Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.35757684
102Proteoglycans in cancer_Homo sapiens_hsa052050.35283476
103Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.33236126
104Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.32604985
105Butanoate metabolism_Homo sapiens_hsa006500.32595435
106Arachidonic acid metabolism_Homo sapiens_hsa005900.31803055
1072-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.30154676
108Pentose and glucuronate interconversions_Homo sapiens_hsa000400.30084697
109Fatty acid degradation_Homo sapiens_hsa000710.29840805
110Parkinsons disease_Homo sapiens_hsa050120.28866994
111Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.28526955
112Notch signaling pathway_Homo sapiens_hsa043300.28371269
113Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.28230931
114Pathways in cancer_Homo sapiens_hsa052000.26856216
115Linoleic acid metabolism_Homo sapiens_hsa005910.25885746
116Metabolic pathways_Homo sapiens_hsa011000.25705920
117Vitamin digestion and absorption_Homo sapiens_hsa049770.25165070
118Retinol metabolism_Homo sapiens_hsa008300.24876439
119Fatty acid metabolism_Homo sapiens_hsa012120.24254009
120Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.24056878
121Propanoate metabolism_Homo sapiens_hsa006400.24020085
122Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.23985401
123Leukocyte transendothelial migration_Homo sapiens_hsa046700.23669521
124Primary bile acid biosynthesis_Homo sapiens_hsa001200.23411311
125Arginine and proline metabolism_Homo sapiens_hsa003300.23252664
126Other glycan degradation_Homo sapiens_hsa005110.22620335
127TNF signaling pathway_Homo sapiens_hsa046680.22318126
128Colorectal cancer_Homo sapiens_hsa052100.21834091
129Prostate cancer_Homo sapiens_hsa052150.20728892
130beta-Alanine metabolism_Homo sapiens_hsa004100.20174449
131Regulation of actin cytoskeleton_Homo sapiens_hsa048100.19097070
132Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.17866488
133Melanoma_Homo sapiens_hsa052180.17317859
134Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.16351566
135Peroxisome_Homo sapiens_hsa041460.15111941
136FoxO signaling pathway_Homo sapiens_hsa040680.14873431
137Renal cell carcinoma_Homo sapiens_hsa052110.13457640
138PI3K-Akt signaling pathway_Homo sapiens_hsa041510.10224171
139Central carbon metabolism in cancer_Homo sapiens_hsa052300.10110135

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