NEFL

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* neurofilament cytoskeleton organization (GO:0060052)9.06991081
2pyrimidine nucleobase catabolic process (GO:0006208)5.64808146
3neuronal action potential propagation (GO:0019227)5.50884056
4synaptic vesicle maturation (GO:0016188)5.44907139
5cell migration in hindbrain (GO:0021535)5.41284762
6negative regulation of dendrite morphogenesis (GO:0050774)5.38744736
7negative regulation of synaptic transmission, glutamatergic (GO:0051967)5.24108647
8ionotropic glutamate receptor signaling pathway (GO:0035235)5.23820528
9detection of temperature stimulus (GO:0016048)5.14767654
10glutamate secretion (GO:0014047)4.80148661
11synaptic vesicle exocytosis (GO:0016079)4.76844071
12regulation of short-term neuronal synaptic plasticity (GO:0048172)4.72919964
13regulation of synaptic vesicle exocytosis (GO:2000300)4.66589070
14nucleobase catabolic process (GO:0046113)4.60896827
15synaptic transmission, glutamatergic (GO:0035249)4.53840838
16proline transport (GO:0015824)4.53301639
17postsynaptic membrane organization (GO:0001941)4.49450222
18detection of temperature stimulus involved in sensory perception of pain (GO:0050965)4.48920137
19detection of temperature stimulus involved in sensory perception (GO:0050961)4.48920137
20negative regulation of microtubule polymerization (GO:0031115)4.48166845
21regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)4.44219961
22membrane depolarization during action potential (GO:0086010)4.35668243
23positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.29882461
24neuronal action potential (GO:0019228)4.29397113
25neuromuscular process controlling posture (GO:0050884)4.22961034
26neuron-neuron synaptic transmission (GO:0007270)4.22467362
27cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.18862573
28neurotransmitter secretion (GO:0007269)4.18255955
29* axon cargo transport (GO:0008088)4.18243553
30glutamate receptor signaling pathway (GO:0007215)4.11660746
31sodium ion export (GO:0071436)4.07973120
32cellular potassium ion homeostasis (GO:0030007)4.06161757
33regulation of synaptic vesicle transport (GO:1902803)4.04551844
34establishment of mitochondrion localization (GO:0051654)4.01408509
35neurotransmitter-gated ion channel clustering (GO:0072578)4.01407774
36negative regulation of dendrite development (GO:2000171)3.99823610
37positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.99240103
38establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.97830289
39mitochondrion transport along microtubule (GO:0047497)3.97830289
40dendritic spine morphogenesis (GO:0060997)3.95938474
41cell communication by electrical coupling (GO:0010644)3.94564518
42protein localization to synapse (GO:0035418)3.94378052
43presynaptic membrane organization (GO:0097090)3.92110906
44presynaptic membrane assembly (GO:0097105)3.87897544
45cerebellar Purkinje cell differentiation (GO:0021702)3.85392477
46neuron cell-cell adhesion (GO:0007158)3.82826926
47cell communication involved in cardiac conduction (GO:0086065)3.77577813
48regulation of excitatory postsynaptic membrane potential (GO:0060079)3.75040433
49innervation (GO:0060384)3.72449019
50locomotory exploration behavior (GO:0035641)3.71286672
51regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.70315568
52calcium-mediated signaling using intracellular calcium source (GO:0035584)3.68909056
53auditory behavior (GO:0031223)3.68789903
54positive regulation of membrane potential (GO:0045838)3.68614445
55organelle transport along microtubule (GO:0072384)3.65909386
56negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.65708950
57synaptic vesicle docking involved in exocytosis (GO:0016081)3.64251985
58* intermediate filament organization (GO:0045109)3.61366810
59positive regulation of potassium ion transmembrane transport (GO:1901381)3.59366778
60neuromuscular synaptic transmission (GO:0007274)3.59084226
61regulation of postsynaptic membrane potential (GO:0060078)3.58930711
62activation of protein kinase A activity (GO:0034199)3.55752058
63neuronal ion channel clustering (GO:0045161)3.49651860
64regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.48850193
65exploration behavior (GO:0035640)3.48775016
66vesicle transport along microtubule (GO:0047496)3.47749079
67membrane repolarization during cardiac muscle cell action potential (GO:0086013)3.47106362
68regulation of voltage-gated calcium channel activity (GO:1901385)3.45250763
69positive regulation of synapse maturation (GO:0090129)3.44137610
70membrane hyperpolarization (GO:0060081)3.42586785
71layer formation in cerebral cortex (GO:0021819)3.42420713
72regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.40405304
73membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.40164209
74regulation of synaptic transmission, glutamatergic (GO:0051966)3.39297885
75plasma membrane repair (GO:0001778)3.32691600
76vocalization behavior (GO:0071625)3.31127503
77membrane repolarization (GO:0086009)3.30873495
78regulation of neuronal synaptic plasticity (GO:0048168)3.28955333
79gamma-aminobutyric acid signaling pathway (GO:0007214)3.28446900
80response to auditory stimulus (GO:0010996)3.28019161
81positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.27822636
82peripheral nervous system neuron development (GO:0048935)3.26627116
83neurotransmitter transport (GO:0006836)3.26575271
84positive regulation of dendritic spine morphogenesis (GO:0061003)3.25570400
85regulation of long-term neuronal synaptic plasticity (GO:0048169)3.25470498
86regulation of dendritic spine morphogenesis (GO:0061001)3.23597334
87synaptic vesicle endocytosis (GO:0048488)3.23318016
88regulation of translational termination (GO:0006449)3.23047323
89positive regulation of potassium ion transport (GO:0043268)3.22519866
90synapse assembly (GO:0007416)3.21184794
91positive regulation of dendritic spine development (GO:0060999)3.20038031
92cerebellar Purkinje cell layer development (GO:0021680)3.18208345
93positive regulation of neurotransmitter transport (GO:0051590)3.18100464
94regulation of neurotransmitter transport (GO:0051588)3.17807220
95positive regulation of axon extension (GO:0045773)3.17187329
96cerebellar granule cell differentiation (GO:0021707)3.14003149
97positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.13077483
98regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.12156548
99long-term memory (GO:0007616)3.11460723
100negative regulation of synaptic transmission, GABAergic (GO:0032229)3.10658129
101regulation of synaptic transmission, GABAergic (GO:0032228)3.10086428
102regulation of sodium ion transmembrane transporter activity (GO:2000649)3.09710961
103membrane repolarization during action potential (GO:0086011)3.08681570
104regulation of synapse structural plasticity (GO:0051823)3.08062241
105regulation of respiratory system process (GO:0044065)3.07565630
106regulation of glutamate receptor signaling pathway (GO:1900449)3.05448461
107behavioral response to cocaine (GO:0048148)3.05422168
108regulation of neurotransmitter levels (GO:0001505)3.02263683
109G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.00330904
110positive regulation of neurotransmitter secretion (GO:0001956)3.00180327
111regulation of synaptic plasticity (GO:0048167)2.99776540
112positive regulation of amino acid transport (GO:0051957)2.98343855
113glycine transport (GO:0015816)2.98177253
114response to acidic pH (GO:0010447)2.97723569
115dendrite morphogenesis (GO:0048813)2.97434533
116positive regulation of synaptic transmission, GABAergic (GO:0032230)2.97362765
117adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.95771939
118cellular sodium ion homeostasis (GO:0006883)2.94818787
119* intermediate filament cytoskeleton organization (GO:0045104)2.93480193
120neuron recognition (GO:0008038)2.91227350
121action potential (GO:0001508)2.90687982
122* intermediate filament-based process (GO:0045103)2.90533894
123calcium ion-dependent exocytosis (GO:0017156)2.90448805
124regulation of axon extension (GO:0030516)2.87712377
125membrane depolarization (GO:0051899)2.87618103
126axonal fasciculation (GO:0007413)2.86446901
127regulation of vesicle fusion (GO:0031338)2.86353929
128potassium ion homeostasis (GO:0055075)2.84106803
129* neuromuscular process controlling balance (GO:0050885)2.84049296
130axon extension (GO:0048675)2.82798452
131* cytoskeleton-dependent intracellular transport (GO:0030705)2.81947018
132* microtubule-based transport (GO:0010970)2.81433337
133sodium ion transmembrane transport (GO:0035725)2.81120144
134* neuromuscular process (GO:0050905)2.79597812
135regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.79174040
136regulation of NFAT protein import into nucleus (GO:0051532)2.78253095
137mating behavior (GO:0007617)2.77921190
138retinal ganglion cell axon guidance (GO:0031290)2.77527107
139transmission of nerve impulse (GO:0019226)2.77499848
140regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.77097759
141negative regulation of potassium ion transmembrane transport (GO:1901380)2.75514049
142adult walking behavior (GO:0007628)2.74238835
143regulation of neurotransmitter secretion (GO:0046928)2.73698725
144gamma-aminobutyric acid transport (GO:0015812)2.73282646
145regulation of membrane repolarization (GO:0060306)2.73172041

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.17967520
2* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.22709670
3GBX2_23144817_ChIP-Seq_PC3_Human3.11991185
4* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.11892233
5* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.94852650
6* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.93155304
7* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.83894608
8* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.83894608
9* REST_21632747_ChIP-Seq_MESCs_Mouse2.81266630
10* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.64187043
11* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.60173714
12* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.57880049
13* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.45673416
14* REST_18959480_ChIP-ChIP_MESCs_Mouse2.39185088
15* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.33779640
16EZH2_27294783_Chip-Seq_ESCs_Mouse2.29640163
17* EZH2_27304074_Chip-Seq_ESCs_Mouse2.28841976
18* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.21206629
19TAF15_26573619_Chip-Seq_HEK293_Human2.16798119
20RARB_27405468_Chip-Seq_BRAIN_Mouse2.16772741
21* RNF2_27304074_Chip-Seq_ESCs_Mouse2.11785162
22NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.08476860
23* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.03233002
24* EED_16625203_ChIP-ChIP_MESCs_Mouse1.97686544
25IKZF1_21737484_ChIP-ChIP_HCT116_Human1.95607381
26DROSHA_22980978_ChIP-Seq_HELA_Human1.95347371
27* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.87014131
28AR_21572438_ChIP-Seq_LNCaP_Human1.77540809
29* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.70008043
30IGF1R_20145208_ChIP-Seq_DFB_Human1.69975968
31SMAD4_21799915_ChIP-Seq_A2780_Human1.69842003
32RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.69834200
33MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.69517280
34ERG_21242973_ChIP-ChIP_JURKAT_Human1.69470485
35* NR3C1_23031785_ChIP-Seq_PC12_Mouse1.69451050
36ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.63726285
37ZNF274_21170338_ChIP-Seq_K562_Hela1.59689866
38CTBP2_25329375_ChIP-Seq_LNCAP_Human1.57542861
39CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.55248396
40CDX2_19796622_ChIP-Seq_MESCs_Mouse1.50415210
41* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.45475744
42PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.42176276
43HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.41449068
44* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.40060362
45KDM2B_26808549_Chip-Seq_K562_Human1.40010593
46SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39395509
47CTBP1_25329375_ChIP-Seq_LNCAP_Human1.33322682
48GATA1_26923725_Chip-Seq_HPCs_Mouse1.29169555
49* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.28255898
50SOX2_21211035_ChIP-Seq_LN229_Gbm1.28013611
51GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.27935029
52SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.27820560
53* RING1B_27294783_Chip-Seq_ESCs_Mouse1.27818723
54* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.26794236
55RBPJ_22232070_ChIP-Seq_NCS_Mouse1.24964596
56ESR2_21235772_ChIP-Seq_MCF-7_Human1.24732308
57P300_19829295_ChIP-Seq_ESCs_Human1.23433582
58TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.22558398
59DNAJC2_21179169_ChIP-ChIP_NT2_Human1.21109207
60* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.20943396
61FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.17452600
62STAT3_23295773_ChIP-Seq_U87_Human1.17175706
63ESR1_20079471_ChIP-ChIP_T-47D_Human1.17149395
64OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16400480
65AHR_22903824_ChIP-Seq_MCF-7_Human1.16294560
66AR_25329375_ChIP-Seq_VCAP_Human1.15827071
67EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.15173197
68* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.13724098
69TET1_21490601_ChIP-Seq_MESCs_Mouse1.13639864
70TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13428429
71* AR_19668381_ChIP-Seq_PC3_Human1.11776155
72RNF2_27304074_Chip-Seq_NSC_Mouse1.11613602
73* CTCF_27219007_Chip-Seq_Bcells_Human1.11370993
74THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.11020266
75CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.10837501
76* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.09758467
77TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.09253169
78RING1B_27294783_Chip-Seq_NPCs_Mouse1.07123244
79TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.05821468
80SMAD3_21741376_ChIP-Seq_ESCs_Human1.03774613
81WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.03741444
82SMAD3_21741376_ChIP-Seq_EPCs_Human1.03626219
83* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.02904494
84ZFP57_27257070_Chip-Seq_ESCs_Mouse1.02680905
85SMAD4_21741376_ChIP-Seq_HESCs_Human0.99093268
86TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97243932
87ARNT_22903824_ChIP-Seq_MCF-7_Human0.97013250
88LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96931372
89PRDM14_20953172_ChIP-Seq_ESCs_Human0.96215274
90MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95665675
91POU3F2_20337985_ChIP-ChIP_501MEL_Human0.95629509
92YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94104490
93MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.92697993
94VDR_22108803_ChIP-Seq_LS180_Human0.92576951
95CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.91436836
96FUS_26573619_Chip-Seq_HEK293_Human0.90853777
97* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.90709529
98SOX9_26525672_Chip-Seq_HEART_Mouse0.90426417
99ZNF217_24962896_ChIP-Seq_MCF-7_Human0.90134121
100KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.89582403
101MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.89447370
102POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.88612043
103TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88612043
104TCF4_23295773_ChIP-Seq_U87_Human0.88205193
105SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.87919823
106PIAS1_25552417_ChIP-Seq_VCAP_Human0.87651614
107KLF5_20875108_ChIP-Seq_MESCs_Mouse0.87336692
108AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.87018881
109JUN_21703547_ChIP-Seq_K562_Human0.86199992
110P53_22127205_ChIP-Seq_FIBROBLAST_Human0.86089246
111CBX2_27304074_Chip-Seq_ESCs_Mouse0.85991802
112BCAT_22108803_ChIP-Seq_LS180_Human0.85895561
113KDM2B_26808549_Chip-Seq_REH_Human0.85512331
114SMAD4_21741376_ChIP-Seq_EPCs_Human0.85181680
115CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.84256954
116MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.83912982
117REST_19997604_ChIP-ChIP_NEURONS_Mouse0.83335982
118* TP53_20018659_ChIP-ChIP_R1E_Mouse0.82686089
119STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.82466779
120CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.81366601
121CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80815569
122TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.80170248
123* KLF4_19829295_ChIP-Seq_ESCs_Human0.79747518

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002735_abnormal_chemical_nociception5.40648411
2MP0001968_abnormal_touch/_nociception4.91785573
3MP0002736_abnormal_nociception_after4.62912889
4MP0004859_abnormal_synaptic_plasticity4.58562003
5MP0004270_analgesia4.51554391
6MP0004858_abnormal_nervous_system4.03463833
7MP0003880_abnormal_central_pattern3.88200377
8MP0002734_abnormal_mechanical_nocicepti3.60973172
9MP0006276_abnormal_autonomic_nervous3.58130915
10MP0002733_abnormal_thermal_nociception3.42407724
11MP0003635_abnormal_synaptic_transmissio3.12258279
12MP0001970_abnormal_pain_threshold2.90417555
13MP0009046_muscle_twitch2.88343558
14MP0002272_abnormal_nervous_system2.68852500
15MP0002184_abnormal_innervation2.55146904
16MP0005423_abnormal_somatic_nervous2.44906848
17MP0002063_abnormal_learning/memory/cond2.39842891
18MP0009745_abnormal_behavioral_response2.33973801
19MP0002064_seizures2.32726040
20MP0003329_amyloid_beta_deposits2.31881051
21MP0000955_abnormal_spinal_cord2.31073093
22MP0001986_abnormal_taste_sensitivity2.25098052
23MP0002067_abnormal_sensory_capabilities2.24936920
24MP0004811_abnormal_neuron_physiology2.12459553
25MP0001348_abnormal_lacrimal_gland1.94955290
26MP0002572_abnormal_emotion/affect_behav1.90291562
27MP0001188_hyperpigmentation1.89690966
28MP0001486_abnormal_startle_reflex1.84251435
29MP0004142_abnormal_muscle_tone1.75478531
30MP0002638_abnormal_pupillary_reflex1.75303830
31MP0000778_abnormal_nervous_system1.71659592
32MP0008569_lethality_at_weaning1.56861951
33MP0004147_increased_porphyrin_level1.56727278
34MP0002751_abnormal_autonomic_nervous1.54077870
35MP0001440_abnormal_grooming_behavior1.53628146
36* MP0002882_abnormal_neuron_morphology1.51117711
37MP0002909_abnormal_adrenal_gland1.47918552
38MP0003121_genomic_imprinting1.40184825
39MP0005386_behavior/neurological_phenoty1.38641424
40MP0004924_abnormal_behavior1.38641424
41MP0002066_abnormal_motor_capabilities/c1.31825797
42* MP0002229_neurodegeneration1.28275749
43MP0002557_abnormal_social/conspecific_i1.27815342
44MP0000751_myopathy1.26969049
45MP0001501_abnormal_sleep_pattern1.26808431
46MP0000604_amyloidosis1.19258238
47MP0008877_abnormal_DNA_methylation1.14326161
48MP0001177_atelectasis1.12625662
49MP0001299_abnormal_eye_distance/1.09025549
50* MP0002752_abnormal_somatic_nervous1.08233531
51MP0003634_abnormal_glial_cell1.07554328
52MP0003879_abnormal_hair_cell1.07496096
53MP0001984_abnormal_olfaction1.04979355
54MP0009780_abnormal_chondrocyte_physiolo1.04082268
55* MP0003633_abnormal_nervous_system1.01109563
56MP0003123_paternal_imprinting1.00216698
57MP0004145_abnormal_muscle_electrophysio1.00064771
58MP0000534_abnormal_ureter_morphology0.99304968
59MP0005083_abnormal_biliary_tract0.97306453
60MP0001346_abnormal_lacrimal_gland0.96462445
61MP0005551_abnormal_eye_electrophysiolog0.91408078
62* MP0003631_nervous_system_phenotype0.90194156
63MP0005623_abnormal_meninges_morphology0.90008668
64MP0000920_abnormal_myelination0.87804377
65MP0005187_abnormal_penis_morphology0.87436639
66MP0002653_abnormal_ependyma_morphology0.84807889
67MP0001529_abnormal_vocalization0.83202964
68MP0002822_catalepsy0.83104189
69MP0003122_maternal_imprinting0.82795506
70MP0000569_abnormal_digit_pigmentation0.82791831
71MP0003690_abnormal_glial_cell0.82592113
72MP0001963_abnormal_hearing_physiology0.78930804
73MP0002152_abnormal_brain_morphology0.77940996
74MP0000747_muscle_weakness0.76292054
75MP0005394_taste/olfaction_phenotype0.75652784
76MP0005499_abnormal_olfactory_system0.75652784
77MP0000631_abnormal_neuroendocrine_gland0.75157298
78MP0002102_abnormal_ear_morphology0.74074272
79MP0000026_abnormal_inner_ear0.72023443
80MP0004885_abnormal_endolymph0.71994280
81MP0004085_abnormal_heartbeat0.70374191
82MP0004742_abnormal_vestibular_system0.70133063
83MP0003632_abnormal_nervous_system0.70038758
84MP0002837_dystrophic_cardiac_calcinosis0.70014682
85MP0008874_decreased_physiological_sensi0.69671677
86MP0003283_abnormal_digestive_organ0.67337920
87MP0000566_synostosis0.66753150
88MP0001485_abnormal_pinna_reflex0.66274263
89MP0001905_abnormal_dopamine_level0.66220014
90MP0003183_abnormal_peptide_metabolism0.66110985
91MP0005409_darkened_coat_color0.66051353
92MP0008260_abnormal_autophagy0.65986252
93MP0004133_heterotaxia0.65461422
94MP0001270_distended_abdomen0.64975549
95MP0000538_abnormal_urinary_bladder0.64222603
96MP0008872_abnormal_physiological_respon0.64059458
97MP0010768_mortality/aging0.63020620
98MP0003119_abnormal_digestive_system0.62144252
99MP0003938_abnormal_ear_development0.61732994
100MP0005645_abnormal_hypothalamus_physiol0.61603401
101MP0001502_abnormal_circadian_rhythm0.61425253
102MP0005535_abnormal_body_temperature0.61417707
103MP0002081_perinatal_lethality0.59678249
104MP0000537_abnormal_urethra_morphology0.59655082
105MP0002069_abnormal_eating/drinking_beha0.58832206
106MP0005248_abnormal_Harderian_gland0.55619517
107MP0003656_abnormal_erythrocyte_physiolo0.55377528
108MP0002269_muscular_atrophy0.55085253
109MP0004883_abnormal_blood_vessel0.55050110
110MP0001943_abnormal_respiration0.54264337
111MP0006072_abnormal_retinal_apoptosis0.54243649
112MP0000749_muscle_degeneration0.54163504
113MP0003956_abnormal_body_size0.51729841
114MP0010386_abnormal_urinary_bladder0.51146506
115MP0000759_abnormal_skeletal_muscle0.51141903
116MP0001664_abnormal_digestion0.49743619
117MP0003861_abnormal_nervous_system0.49341764
118MP0005646_abnormal_pituitary_gland0.47329439
119MP0003787_abnormal_imprinting0.46767395
120MP0004036_abnormal_muscle_relaxation0.46621125
121MP0004215_abnormal_myocardial_fiber0.46592198
122MP0003137_abnormal_impulse_conducting0.46082788
123MP0004233_abnormal_muscle_weight0.45833856
124MP0010769_abnormal_survival0.45385542
125MP0004484_altered_response_of0.44315366
126MP0010770_preweaning_lethality0.44299000
127MP0002082_postnatal_lethality0.44299000

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)7.67556245
2Action tremor (HP:0002345)5.57526870
3Supranuclear gaze palsy (HP:0000605)5.21192620
4Focal motor seizures (HP:0011153)4.96322582
5Pheochromocytoma (HP:0002666)4.92525420
6Termporal pattern (HP:0011008)4.89041759
7Insidious onset (HP:0003587)4.89041759
8Focal seizures (HP:0007359)4.58296778
9Atonic seizures (HP:0010819)4.41357994
10Neuroendocrine neoplasm (HP:0100634)4.40663615
11* Ulnar claw (HP:0001178)4.30397251
12Ankle clonus (HP:0011448)4.19126782
13Febrile seizures (HP:0002373)4.18159820
14Progressive cerebellar ataxia (HP:0002073)3.96217689
15Urinary urgency (HP:0000012)3.56566060
16Polyphagia (HP:0002591)3.55038945
17Visual hallucinations (HP:0002367)3.51129041
18Abnormality of pain sensation (HP:0010832)3.46196186
19Impaired pain sensation (HP:0007328)3.46196186
20Absence seizures (HP:0002121)3.23181934
21Abnormality of the corticospinal tract (HP:0002492)3.22589366
22Failure to thrive in infancy (HP:0001531)3.18684783
23Ventricular fibrillation (HP:0001663)3.18437956
24Decreased number of large peripheral myelinated nerve fibers (HP:0003387)3.18199389
25Spastic gait (HP:0002064)3.18037434
26Epileptic encephalopathy (HP:0200134)3.12321388
27Abnormality of binocular vision (HP:0011514)3.09946947
28Diplopia (HP:0000651)3.09946947
29Truncal ataxia (HP:0002078)3.03450292
30Gait imbalance (HP:0002141)3.02946363
31Abnormality of the lower motor neuron (HP:0002366)3.02632945
32Neoplasm of the peripheral nervous system (HP:0100007)3.00657929
33Generalized tonic-clonic seizures (HP:0002069)3.00021224
34Amyotrophic lateral sclerosis (HP:0007354)2.99277473
35Abnormality of the vocal cords (HP:0008777)2.98699423
36Hypercortisolism (HP:0001578)2.98202241
37Urinary bladder sphincter dysfunction (HP:0002839)2.97044059
38Epileptiform EEG discharges (HP:0011182)2.95563653
39Dialeptic seizures (HP:0011146)2.90554944
40Impaired vibration sensation in the lower limbs (HP:0002166)2.85082397
41* Hammertoe (HP:0001765)2.84357249
42Aplasia/Hypoplasia of the brainstem (HP:0007362)2.81292297
43Hypoplasia of the brainstem (HP:0002365)2.81292297
44Drooling (HP:0002307)2.79818736
45Status epilepticus (HP:0002133)2.77002513
46Amblyopia (HP:0000646)2.76637136
47Neurofibrillary tangles (HP:0002185)2.75804277
48Lower limb asymmetry (HP:0100559)2.73876948
49EEG with generalized epileptiform discharges (HP:0011198)2.69744258
50Hemiparesis (HP:0001269)2.67635577
51Dysautonomia (HP:0002459)2.61570668
52Hypsarrhythmia (HP:0002521)2.61433124
53Lower limb muscle weakness (HP:0007340)2.58391740
54Abnormal eating behavior (HP:0100738)2.57922976
55Depression (HP:0000716)2.56829464
56Excessive salivation (HP:0003781)2.56771222
57* Distal sensory impairment (HP:0002936)2.55530856
58Intention tremor (HP:0002080)2.54588173
59Sleep apnea (HP:0010535)2.54373521
60Broad-based gait (HP:0002136)2.53892860
61Scanning speech (HP:0002168)2.51096575
62Hypoventilation (HP:0002791)2.50433033
63Spastic tetraplegia (HP:0002510)2.50349179
64* Foot dorsiflexor weakness (HP:0009027)2.48772283
65Insomnia (HP:0100785)2.45786696
66Hemiplegia (HP:0002301)2.41248959
67Paraplegia (HP:0010550)2.39207073
68Annular pancreas (HP:0001734)2.33324725
69Peripheral hypomyelination (HP:0007182)2.31556429
70Fetal akinesia sequence (HP:0001989)2.30646896
71* Decreased number of peripheral myelinated nerve fibers (HP:0003380)2.29210760
72Myotonia (HP:0002486)2.27906134
73Spastic paraplegia (HP:0001258)2.25321329
74Cortical dysplasia (HP:0002539)2.24843472
75Dysmetria (HP:0001310)2.24503911
76Congenital primary aphakia (HP:0007707)2.24215279
77Hyporeflexia of lower limbs (HP:0002600)2.23325930
78Specific learning disability (HP:0001328)2.22391317
79* Abnormality of the foot musculature (HP:0001436)2.21910483
80Mutism (HP:0002300)2.21733760
81Cerebral hypomyelination (HP:0006808)2.19778731
82Anxiety (HP:0000739)2.17992906
83* Steppage gait (HP:0003376)2.17249906
84Genetic anticipation (HP:0003743)2.17148757
85Nephrogenic diabetes insipidus (HP:0009806)2.17146117
86Clonus (HP:0002169)2.14145128
87Slow saccadic eye movements (HP:0000514)2.13577848
88Gaze-evoked nystagmus (HP:0000640)2.12762986
89Lower limb amyotrophy (HP:0007210)2.12674808
90Cerebral inclusion bodies (HP:0100314)2.12273429
91Postural instability (HP:0002172)2.10710339
92Torticollis (HP:0000473)2.10153759
93Progressive inability to walk (HP:0002505)2.09954877
94Rapidly progressive (HP:0003678)2.08015169
95Postural tremor (HP:0002174)2.04599632
96Cerebral hemorrhage (HP:0001342)2.00626099
97Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.00059039
98Degeneration of the lateral corticospinal tracts (HP:0002314)2.00059039
99Distal arthrogryposis (HP:0005684)1.99037952
100Apathy (HP:0000741)1.98932244
101Thyroid carcinoma (HP:0002890)1.98589464
102Aqueductal stenosis (HP:0002410)1.98290952
103* Decreased motor nerve conduction velocity (HP:0003431)1.98076674
104Atrophy/Degeneration involving motor neurons (HP:0007373)1.97987323
105Akinesia (HP:0002304)1.97284017
106Medial flaring of the eyebrow (HP:0010747)1.97246298
107Morphological abnormality of the pyramidal tract (HP:0002062)1.95893783
108CNS hypomyelination (HP:0003429)1.95438431
109Vaginal atresia (HP:0000148)1.95415038
110Impaired social interactions (HP:0000735)1.93683476
111Abnormal social behavior (HP:0012433)1.93683476
112Poor suck (HP:0002033)1.93630928
113Bradykinesia (HP:0002067)1.92910502
114Muscle stiffness (HP:0003552)1.92473463
115Bradycardia (HP:0001662)1.92185602
116Genital tract atresia (HP:0001827)1.91413106
117Hypoplasia of the corpus callosum (HP:0002079)1.91370399
118Delusions (HP:0000746)1.90686201
119Impaired smooth pursuit (HP:0007772)1.90270136
120Agitation (HP:0000713)1.90164419
121Dysdiadochokinesis (HP:0002075)1.88680658
122Poor eye contact (HP:0000817)1.88201257
123Pointed chin (HP:0000307)1.88019483
124Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.87403329
125Impaired vibratory sensation (HP:0002495)1.87197740
126Hyperventilation (HP:0002883)1.87046186
127Abnormality of calcium-phosphate metabolism (HP:0100530)1.86014500
128Anosmia (HP:0000458)1.86014299
129Abnormality of the labia minora (HP:0012880)1.85801483
130Incomplete penetrance (HP:0003829)1.85420367
131Pachygyria (HP:0001302)1.84700134
132Lissencephaly (HP:0001339)1.83351492
133Craniofacial dystonia (HP:0012179)1.81219042
134* Onion bulb formation (HP:0003383)1.80345875
135Neuronal loss in central nervous system (HP:0002529)1.78823920
136Focal dystonia (HP:0004373)1.78743831
137Slow progression (HP:0003677)1.78649082
138Limb dystonia (HP:0002451)1.78394486
139Unsteady gait (HP:0002317)1.76240412
140Spastic tetraparesis (HP:0001285)1.71844896
141Muscular hypotonia of the trunk (HP:0008936)1.71065007
142Papilledema (HP:0001085)1.70360084
143Dyskinesia (HP:0100660)1.69435910

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.70810307
2MINK14.60342689
3MAP3K94.15184494
4LMTK24.13964614
5LATS22.92572821
6KSR22.82709715
7MAP3K42.80863106
8MAP3K122.74417781
9MARK12.70614664
10NTRK12.65855913
11LIMK12.41140806
12MAP2K42.24326898
13MAP2K72.20679875
14PHKG12.15212940
15PHKG22.15212940
16PAK62.09384422
17MAP3K21.86726649
18WNK11.79572099
19RET1.75946945
20SCYL21.51148986
21CAMKK11.42462449
22MAPK131.42331247
23MAPKAPK31.32303472
24RIPK41.32112280
25CASK1.28129045
26WNK31.22329050
27ARAF1.20696220
28STK391.17603349
29EPHA41.17102067
30GRK51.16778391
31DYRK1A1.14549654
32DAPK21.12652301
33WNK41.11132729
34MAP4K21.10692749
35PRKCG1.09302418
36STK381.08760275
37KSR11.08407824
38NEK11.06967079
39BMPR1B1.04756771
40* CDK51.03867910
41CSNK1G31.00183608
42FER0.99895494
43TNIK0.98649276
44CAMK2B0.98258248
45SGK4940.94181242
46SGK2230.94181242
47CAMKK20.92870787
48CSNK1A1L0.92543630
49MAP2K10.92112541
50CDK190.91481620
51RPS6KA20.88369813
52UHMK10.86739582
53PRKD30.86431520
54MATK0.84649171
55MAP3K10.83479814
56TRIM280.83311737
57CDK140.77983545
58NTRK20.77626394
59PNCK0.75911586
60MAP3K110.74596253
61CAMK10.73250399
62PAK30.70907451
63CSNK1G10.68358308
64PINK10.67888147
65CDK180.65493452
66PKN10.62025155
67DAPK10.61978547
68ADRBK10.61813869
69CDK150.61365663
70PDPK10.60683500
71CSNK1G20.59908865
72TAOK10.59338463
73MAPK120.58648035
74SGK20.58384347
75PDK10.58346096
76EPHA30.56414089
77CAMK2G0.55402170
78PRKCZ0.55293264
79CDC42BPA0.54795421
80PLK20.54793751
81ROCK20.54468179
82CAMK1G0.53820469
83FES0.53209436
84CDK11A0.51538189
85GRK70.49814716
86SGK30.48398810
87PRKCH0.47988100
88ROCK10.47230713
89SGK10.46619279
90ALK0.44358889
91MAPK100.43996167
92PRKCE0.43281984
93SIK20.42478888
94TNK20.41075953
95CSNK1D0.40812288
96* CAMK2A0.40811054
97STK110.40204357
98FYN0.39675111
99DYRK20.38719940
100ERBB30.37746433
101RAF10.37547274
102PRKG20.37482889
103CAMK2D0.36689748
104CSNK1A10.36124024
105* PRKACA0.35968797
106PRKCA0.34598354
107* CSNK1E0.34477411
108SIK30.34460397
109BRSK10.33783645
110PDK40.33248452
111PDK30.33248452
112CAMK1D0.33224092
113MAPK90.32550333
114ADRBK20.32426397
115MAPK40.32307780
116TESK10.30660789
117ERBB20.30619315
118PTK2B0.30581610
119PTK20.30259004
120OXSR10.30123398
121CAMK40.30103597
122PRKG10.29685237
123RPS6KA30.29531188
124MAPK80.29253765
125MAP2K60.29027576
126MARK20.28999451
127BCR0.26544176
128PRKCB0.25459458
129TYRO30.23792328

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.86784541
2Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049613.19668088
3Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.95865252
4Olfactory transduction_Homo sapiens_hsa047402.47662449
5Nicotine addiction_Homo sapiens_hsa050332.34361581
6Long-term potentiation_Homo sapiens_hsa047202.16303483
7Dopaminergic synapse_Homo sapiens_hsa047282.01925594
8Circadian entrainment_Homo sapiens_hsa047131.95698256
9* Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.92779336
10Cholinergic synapse_Homo sapiens_hsa047251.92672325
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.80507026
12Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.80063926
13Insulin secretion_Homo sapiens_hsa049111.77619224
14Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.74571244
15Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.73815970
16GABAergic synapse_Homo sapiens_hsa047271.73008054
17Taste transduction_Homo sapiens_hsa047421.72833467
18Salivary secretion_Homo sapiens_hsa049701.72010187
19Glutamatergic synapse_Homo sapiens_hsa047241.71995692
20Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.67900233
21Gastric acid secretion_Homo sapiens_hsa049711.66962012
22Amphetamine addiction_Homo sapiens_hsa050311.64753335
23GnRH signaling pathway_Homo sapiens_hsa049121.48659205
24Dorso-ventral axis formation_Homo sapiens_hsa043201.44753151
25Morphine addiction_Homo sapiens_hsa050321.43833581
26Collecting duct acid secretion_Homo sapiens_hsa049661.39407323
27Gap junction_Homo sapiens_hsa045401.38088580
28Aldosterone synthesis and secretion_Homo sapiens_hsa049251.33858335
29Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.29000173
30Glioma_Homo sapiens_hsa052141.28854781
31Oxytocin signaling pathway_Homo sapiens_hsa049211.28133637
32Neurotrophin signaling pathway_Homo sapiens_hsa047221.27208386
33Serotonergic synapse_Homo sapiens_hsa047261.24144941
34Oocyte meiosis_Homo sapiens_hsa041141.22224737
35Long-term depression_Homo sapiens_hsa047301.22195054
36Renin secretion_Homo sapiens_hsa049241.20959682
37Cardiac muscle contraction_Homo sapiens_hsa042601.19531607
38Axon guidance_Homo sapiens_hsa043601.18044920
39ErbB signaling pathway_Homo sapiens_hsa040121.18025769
40Phosphatidylinositol signaling system_Homo sapiens_hsa040701.17802667
41Calcium signaling pathway_Homo sapiens_hsa040201.13077466
42Estrogen signaling pathway_Homo sapiens_hsa049151.09807586
43Vibrio cholerae infection_Homo sapiens_hsa051101.07224479
44Type II diabetes mellitus_Homo sapiens_hsa049301.05697254
45VEGF signaling pathway_Homo sapiens_hsa043700.94240945
46Insulin signaling pathway_Homo sapiens_hsa049100.93831035
47Melanogenesis_Homo sapiens_hsa049160.90410419
48cAMP signaling pathway_Homo sapiens_hsa040240.90381508
49Central carbon metabolism in cancer_Homo sapiens_hsa052300.87896231
50Thyroid cancer_Homo sapiens_hsa052160.83662240
51Cocaine addiction_Homo sapiens_hsa050300.83473844
52Phospholipase D signaling pathway_Homo sapiens_hsa040720.81825047
53Endometrial cancer_Homo sapiens_hsa052130.77601797
54Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.77160177
55Choline metabolism in cancer_Homo sapiens_hsa052310.77109871
56Sphingolipid signaling pathway_Homo sapiens_hsa040710.76798917
57Salmonella infection_Homo sapiens_hsa051320.76678916
58Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.75736908
59Endocytosis_Homo sapiens_hsa041440.75339893
60Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.74767786
61Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.73907494
62Glucagon signaling pathway_Homo sapiens_hsa049220.73471805
63SNARE interactions in vesicular transport_Homo sapiens_hsa041300.73398722
64Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.73158522
65Parkinsons disease_Homo sapiens_hsa050120.73140033
66Alzheimers disease_Homo sapiens_hsa050100.72387628
67Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.72113718
68Phototransduction_Homo sapiens_hsa047440.69330407
69mTOR signaling pathway_Homo sapiens_hsa041500.68934424
70Vascular smooth muscle contraction_Homo sapiens_hsa042700.68565654
71MAPK signaling pathway_Homo sapiens_hsa040100.68204982
72Carbohydrate digestion and absorption_Homo sapiens_hsa049730.67890614
73Oxidative phosphorylation_Homo sapiens_hsa001900.67805221
74cGMP-PKG signaling pathway_Homo sapiens_hsa040220.67756698
75Alcoholism_Homo sapiens_hsa050340.65103097
76Thyroid hormone synthesis_Homo sapiens_hsa049180.64648698
77Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.63522559
78Melanoma_Homo sapiens_hsa052180.63195488
79Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.62598148
80Prion diseases_Homo sapiens_hsa050200.62162935
81Ras signaling pathway_Homo sapiens_hsa040140.61324185
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.61149646
83Bile secretion_Homo sapiens_hsa049760.61054695
84Rap1 signaling pathway_Homo sapiens_hsa040150.60533627
85Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.58169686
86Pancreatic secretion_Homo sapiens_hsa049720.57956499
87Thyroid hormone signaling pathway_Homo sapiens_hsa049190.56694246
88Prolactin signaling pathway_Homo sapiens_hsa049170.55787621
89Phagosome_Homo sapiens_hsa041450.53213939
90Circadian rhythm_Homo sapiens_hsa047100.52849789
91Inositol phosphate metabolism_Homo sapiens_hsa005620.48512534
92Hippo signaling pathway_Homo sapiens_hsa043900.47744157
93Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.46064041
94Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.46006961
95Non-small cell lung cancer_Homo sapiens_hsa052230.44173061
96Nitrogen metabolism_Homo sapiens_hsa009100.43726436
97Dilated cardiomyopathy_Homo sapiens_hsa054140.42338244
98Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.41474250
99Wnt signaling pathway_Homo sapiens_hsa043100.41072465
100Regulation of autophagy_Homo sapiens_hsa041400.39288026
101Colorectal cancer_Homo sapiens_hsa052100.39201262
102Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.38971884
103Huntingtons disease_Homo sapiens_hsa050160.38818853
104Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.37468861
105Vitamin B6 metabolism_Homo sapiens_hsa007500.37347620
106Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.37212616
107Longevity regulating pathway - mammal_Homo sapiens_hsa042110.36838583
108AMPK signaling pathway_Homo sapiens_hsa041520.35852454
109Pyruvate metabolism_Homo sapiens_hsa006200.34137435
110Protein export_Homo sapiens_hsa030600.34041595
111Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.33184795
112Tight junction_Homo sapiens_hsa045300.32184340
113Renal cell carcinoma_Homo sapiens_hsa052110.31344252
114Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.31236298
115Ovarian steroidogenesis_Homo sapiens_hsa049130.29373006
116Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.29067442
117Fatty acid biosynthesis_Homo sapiens_hsa000610.28017592
118Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.27894513
119Arginine and proline metabolism_Homo sapiens_hsa003300.25191289
120Ether lipid metabolism_Homo sapiens_hsa005650.24017816

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