NEK5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement (GO:0003351)9.95574303
2left/right axis specification (GO:0070986)9.44052749
3GTP biosynthetic process (GO:0006183)8.30288487
4epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.84134074
5motile cilium assembly (GO:0044458)7.79234687
6nucleoside diphosphate phosphorylation (GO:0006165)7.65583768
7intraciliary transport (GO:0042073)7.46626741
8UTP biosynthetic process (GO:0006228)7.37920561
9UTP metabolic process (GO:0046051)6.82608523
10microtubule bundle formation (GO:0001578)6.58134858
11cilium organization (GO:0044782)5.92867993
12guanosine-containing compound biosynthetic process (GO:1901070)5.59668572
13CTP metabolic process (GO:0046036)5.57748310
14CTP biosynthetic process (GO:0006241)5.57748310
15cilium morphogenesis (GO:0060271)5.55646034
16cilium assembly (GO:0042384)5.53022261
17C21-steroid hormone biosynthetic process (GO:0006700)5.48282168
18behavioral response to nicotine (GO:0035095)5.26605272
19pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)5.08181176
20progesterone metabolic process (GO:0042448)4.84137730
21pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)4.81055859
22cellular component assembly involved in morphogenesis (GO:0010927)4.69442550
23regulation of cilium movement (GO:0003352)4.60514141
24microtubule-based movement (GO:0007018)4.39449416
25nucleotide phosphorylation (GO:0046939)4.23042871
26regulation of glucose import in response to insulin stimulus (GO:2001273)4.11442443
27embryonic retina morphogenesis in camera-type eye (GO:0060059)4.10932755
28cell projection assembly (GO:0030031)4.03157063
29embryonic camera-type eye development (GO:0031076)3.96130927
30pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.95737648
31protein polyglutamylation (GO:0018095)3.87213400
32response to pheromone (GO:0019236)3.74564753
33nucleoside diphosphate metabolic process (GO:0009132)3.66605064
34otic vesicle formation (GO:0030916)3.61819870
35L-fucose catabolic process (GO:0042355)3.59901291
36fucose catabolic process (GO:0019317)3.59901291
37L-fucose metabolic process (GO:0042354)3.59901291
38determination of left/right symmetry (GO:0007368)3.58807209
39oxygen transport (GO:0015671)3.56239360
40regulation of macrophage chemotaxis (GO:0010758)3.52669011
41one-carbon compound transport (GO:0019755)3.49294455
42photoreceptor cell differentiation (GO:0046530)3.46962425
43eye photoreceptor cell differentiation (GO:0001754)3.46962425
44pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.46086547
45determination of bilateral symmetry (GO:0009855)3.44656484
46kidney morphogenesis (GO:0060993)3.41633508
47regulation of mononuclear cell migration (GO:0071675)3.40385989
48lateral ventricle development (GO:0021670)3.39585390
49microtubule severing (GO:0051013)3.38803061
50piRNA metabolic process (GO:0034587)3.38449592
51specification of symmetry (GO:0009799)3.35546630
52pyrimidine ribonucleoside biosynthetic process (GO:0046132)3.26600622
53DNA deamination (GO:0045006)3.24901174
54gamma-aminobutyric acid transport (GO:0015812)3.23332802
55smoothened signaling pathway (GO:0007224)3.21966828
56C21-steroid hormone metabolic process (GO:0008207)3.21948150
57sulfation (GO:0051923)3.21389329
58gas transport (GO:0015669)3.18929706
59urinary tract smooth muscle contraction (GO:0014848)3.18328019
60negative regulation of inclusion body assembly (GO:0090084)3.16821414
61exogenous drug catabolic process (GO:0042738)3.14788983
62neuronal action potential (GO:0019228)3.11493636
63positive regulation of cellular response to insulin stimulus (GO:1900078)3.09347475
64pyrimidine ribonucleotide biosynthetic process (GO:0009220)3.08089180
65cellular ketone body metabolic process (GO:0046950)3.07997895
66protein localization to cilium (GO:0061512)3.05534304
67response to xenobiotic stimulus (GO:0009410)3.01889899
68membrane repolarization during action potential (GO:0086011)3.01807298
69nonmotile primary cilium assembly (GO:0035058)2.99125683
70lung epithelium development (GO:0060428)2.97826340
71regulation of transforming growth factor beta2 production (GO:0032909)2.96969514
72postsynaptic membrane organization (GO:0001941)2.96825588
73drug catabolic process (GO:0042737)2.96648102
74detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.93979467
75cornea development in camera-type eye (GO:0061303)2.92848388
76glomerular epithelial cell development (GO:0072310)2.90325288
77negative regulation of telomere maintenance (GO:0032205)2.89487446
78sperm motility (GO:0030317)2.89357634
79cellular response to ATP (GO:0071318)2.87705538
80hair follicle development (GO:0001942)2.86587537
81regulation of mesoderm development (GO:2000380)2.85970440
82multicellular organism reproduction (GO:0032504)2.83422762
83primary amino compound metabolic process (GO:1901160)2.83178035
84regulation of microtubule-based movement (GO:0060632)2.80252783
85indole-containing compound catabolic process (GO:0042436)2.79916598
86indolalkylamine catabolic process (GO:0046218)2.79916598
87tryptophan catabolic process (GO:0006569)2.79916598
88peristalsis (GO:0030432)2.79566089
89pyrimidine ribonucleotide metabolic process (GO:0009218)2.76228326
90ketone body metabolic process (GO:1902224)2.75680096
91photoreceptor cell maintenance (GO:0045494)2.75633926
92centriole assembly (GO:0098534)2.75026670
93serotonin metabolic process (GO:0042428)2.72705057
94peptide hormone processing (GO:0016486)2.72405514
95indolalkylamine metabolic process (GO:0006586)2.72405034
96regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.72362369
97detection of light stimulus involved in sensory perception (GO:0050962)2.71456234
98detection of light stimulus involved in visual perception (GO:0050908)2.71456234
99positive regulation of meiosis (GO:0045836)2.70482346
100DNA methylation involved in gamete generation (GO:0043046)2.67446930
101retinal cone cell development (GO:0046549)2.65885985
102kynurenine metabolic process (GO:0070189)2.62564966
103negative regulation of astrocyte differentiation (GO:0048712)2.62270478
104cardiovascular system development (GO:0072358)2.59163835
105spinal cord motor neuron differentiation (GO:0021522)2.55537060
106glandular epithelial cell differentiation (GO:0002067)2.55144160
107reflex (GO:0060004)2.54284196
108tongue development (GO:0043586)2.54108914
109brain morphogenesis (GO:0048854)2.53016269
110negative regulation of humoral immune response (GO:0002921)2.52664165
111regulation of mesenchymal cell apoptotic process (GO:2001053)2.51941421
112platelet dense granule organization (GO:0060155)2.51506711
113indole-containing compound metabolic process (GO:0042430)2.51496520
114positive regulation of meiotic cell cycle (GO:0051446)2.50781528
115negative regulation of T cell differentiation in thymus (GO:0033085)2.50569238
116pyrimidine ribonucleoside metabolic process (GO:0046131)2.50484083
117embryonic digestive tract development (GO:0048566)2.50403296
118S-adenosylmethionine metabolic process (GO:0046500)2.50303145
119phosphatidylcholine acyl-chain remodeling (GO:0036151)2.50050438
120notochord development (GO:0030903)2.49904352
121muscle organ morphogenesis (GO:0048644)2.48991705
122limb bud formation (GO:0060174)2.48219063
123G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.46589410
124rRNA catabolic process (GO:0016075)2.46501288
125multicellular organismal aging (GO:0010259)2.46405542
126lateral sprouting from an epithelium (GO:0060601)2.44450436
127neurotransmitter metabolic process (GO:0042133)2.43174586
128limb development (GO:0060173)2.42610727
129appendage development (GO:0048736)2.42610727
130auditory behavior (GO:0031223)2.42066394
131Sertoli cell development (GO:0060009)2.41891029
132atrial cardiac muscle cell action potential (GO:0086014)2.41222758
133centriole replication (GO:0007099)2.41087420
134regulation of meiosis I (GO:0060631)2.39548416
135tryptophan metabolic process (GO:0006568)2.39504337
136nephron tubule morphogenesis (GO:0072078)2.38784753
137nephron epithelium morphogenesis (GO:0072088)2.38784753
138regulation of action potential (GO:0098900)2.38206244
139left/right pattern formation (GO:0060972)2.38040508
140SMAD protein signal transduction (GO:0060395)2.37981492
141detection of calcium ion (GO:0005513)2.37668585
142vocalization behavior (GO:0071625)2.37225761
143regulation of hippo signaling (GO:0035330)2.36234068
144photoreceptor cell development (GO:0042461)2.36162069
145potassium ion export (GO:0071435)2.36095945
146transmission of nerve impulse (GO:0019226)2.35262933
147nonribosomal peptide biosynthetic process (GO:0019184)2.34161763
148regulation of collateral sprouting (GO:0048670)2.34020941
149hindbrain development (GO:0030902)2.33555347
150neural tube formation (GO:0001841)2.32656926
151preassembly of GPI anchor in ER membrane (GO:0016254)2.32253257
152detection of mechanical stimulus involved in sensory perception (GO:0050974)2.32133510
153negative regulation of oligodendrocyte differentiation (GO:0048715)2.32007241
154positive regulation of oligodendrocyte differentiation (GO:0048714)2.30586636
155adaptation of signaling pathway (GO:0023058)2.28941198
156cartilage condensation (GO:0001502)2.28734083
157cell aggregation (GO:0098743)2.28734083
158axon ensheathment in central nervous system (GO:0032291)2.27920681
159central nervous system myelination (GO:0022010)2.27920681
160oligodendrocyte differentiation (GO:0048709)2.27655827
161purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.27250155
162cellular response to nicotine (GO:0071316)2.26188467
163protein palmitoylation (GO:0018345)2.26157646
164keratinocyte development (GO:0003334)2.25356290
165endocardial cushion morphogenesis (GO:0003203)2.25314541
166cilium movement (GO:0003341)16.5748916
167axonemal dynein complex assembly (GO:0070286)15.3831242
168axoneme assembly (GO:0035082)13.3533231
169cilium or flagellum-dependent cell motility (GO:0001539)12.2109347
170ventricular system development (GO:0021591)10.0505884

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human3.83968409
2ZNF274_21170338_ChIP-Seq_K562_Hela3.61408764
3VDR_22108803_ChIP-Seq_LS180_Human3.36568910
4EZH2_22144423_ChIP-Seq_EOC_Human3.13236022
5CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.93852426
6GBX2_23144817_ChIP-Seq_PC3_Human2.83998762
7SMAD_19615063_ChIP-ChIP_OVARY_Human2.65089355
8TRIM28_21343339_ChIP-Seq_HEK293_Human2.62762353
9RBPJ_22232070_ChIP-Seq_NCS_Mouse2.60729863
10TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.58158730
11PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.51794406
12AR_21572438_ChIP-Seq_LNCaP_Human2.34365983
13BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.33440357
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.31563349
15PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.24069332
16GATA1_22025678_ChIP-Seq_K562_Human2.20775140
17FUS_26573619_Chip-Seq_HEK293_Human2.11297199
18PIAS1_25552417_ChIP-Seq_VCAP_Human2.09818756
19EWS_26573619_Chip-Seq_HEK293_Human1.96335363
20IGF1R_20145208_ChIP-Seq_DFB_Human1.94725451
21PCGF2_27294783_Chip-Seq_NPCs_Mouse1.90706493
22ER_23166858_ChIP-Seq_MCF-7_Human1.86287938
23SALL1_21062744_ChIP-ChIP_HESCs_Human1.83438429
24SUZ12_27294783_Chip-Seq_NPCs_Mouse1.81129828
25TAF15_26573619_Chip-Seq_HEK293_Human1.75402386
26SMAD4_21799915_ChIP-Seq_A2780_Human1.71066769
27GATA1_26923725_Chip-Seq_HPCs_Mouse1.62587227
28RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.59811955
29LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.57038814
30TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.56147614
31PCGF2_27294783_Chip-Seq_ESCs_Mouse1.55770851
32NFE2_27457419_Chip-Seq_LIVER_Mouse1.55400379
33ARNT_22903824_ChIP-Seq_MCF-7_Human1.54302158
34RNF2_27304074_Chip-Seq_NSC_Mouse1.52427190
35REST_21632747_ChIP-Seq_MESCs_Mouse1.51985371
36SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.51403712
37STAT3_23295773_ChIP-Seq_U87_Human1.51366659
38BCAT_22108803_ChIP-Seq_LS180_Human1.51078320
39GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.50630746
40HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.49932621
41FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.49145503
42CBX2_27304074_Chip-Seq_ESCs_Mouse1.48148909
43AR_25329375_ChIP-Seq_VCAP_Human1.47238594
44NR3C1_21868756_ChIP-Seq_MCF10A_Human1.46495169
45STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.46431183
46ZNF217_24962896_ChIP-Seq_MCF-7_Human1.44252032
47UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.44094238
48TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42117677
49FOXM1_26456572_ChIP-Seq_MCF-7_Human1.40827105
50IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.38213586
51CBP_20019798_ChIP-Seq_JUKART_Human1.38213586
52SALL4_18804426_ChIP-ChIP_XEN_Mouse1.36372929
53P300_19829295_ChIP-Seq_ESCs_Human1.36184540
54NANOG_18555785_Chip-Seq_ESCs_Mouse1.35992618
55CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.35895031
56FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.33046468
57EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.31213018
58TP53_18474530_ChIP-ChIP_U2OS_Human1.30515376
59FLI1_27457419_Chip-Seq_LIVER_Mouse1.29473580
60IRF1_19129219_ChIP-ChIP_H3396_Human1.28996665
61TCF4_22108803_ChIP-Seq_LS180_Human1.28002469
62CJUN_26792858_Chip-Seq_BT549_Human1.27798574
63NANOG_19829295_ChIP-Seq_ESCs_Human1.27586238
64SOX2_19829295_ChIP-Seq_ESCs_Human1.27586238
65TOP2B_26459242_ChIP-Seq_MCF-7_Human1.27516748
66MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.26096251
67CTBP2_25329375_ChIP-Seq_LNCAP_Human1.26040135
68SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.25843725
69POU3F2_20337985_ChIP-ChIP_501MEL_Human1.25708551
70EZH2_27294783_Chip-Seq_ESCs_Mouse1.25113357
71AHR_22903824_ChIP-Seq_MCF-7_Human1.24826303
72EED_16625203_ChIP-ChIP_MESCs_Mouse1.24255313
73E2F1_18555785_Chip-Seq_ESCs_Mouse1.24094930
74CTBP1_25329375_ChIP-Seq_LNCAP_Human1.24056012
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.24027095
76HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.23825450
77STAT3_18555785_Chip-Seq_ESCs_Mouse1.22532066
78EZH2_27294783_Chip-Seq_NPCs_Mouse1.22206096
79GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.20780131
80SMAD3_21741376_ChIP-Seq_EPCs_Human1.20620786
81SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.19981414
82TP53_22573176_ChIP-Seq_HFKS_Human1.19815104
83KAP1_22055183_ChIP-Seq_ESCs_Mouse1.19808665
84CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19483642
85MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.19349212
86GATA3_21878914_ChIP-Seq_MCF-7_Human1.19280398
87DROSHA_22980978_ChIP-Seq_HELA_Human1.19101189
88BMI1_23680149_ChIP-Seq_NPCS_Mouse1.19030148
89P53_22387025_ChIP-Seq_ESCs_Mouse1.18183419
90WDR5_24793694_ChIP-Seq_LNCAP_Human1.17916622
91PRDM14_20953172_ChIP-Seq_ESCs_Human1.17050142
92TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16726809
93RXR_22108803_ChIP-Seq_LS180_Human1.16359663
94AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.16266869
95* LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.16085700
96HOXB7_26014856_ChIP-Seq_BT474_Human1.15071581
97FOXA1_21572438_ChIP-Seq_LNCaP_Human1.14906547
98ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.14018238
99KLF5_20875108_ChIP-Seq_MESCs_Mouse1.13866588
100NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.12145568
101NRF2_20460467_ChIP-Seq_MEFs_Mouse1.11062784
102NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.11062784
103CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.09585678
104CMYC_18555785_Chip-Seq_ESCs_Mouse1.09169634
105SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.09101933
106SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08944133
107SOX2_18555785_Chip-Seq_ESCs_Mouse1.08691281
108ZFX_18555785_Chip-Seq_ESCs_Mouse1.08508633
109TP53_16413492_ChIP-PET_HCT116_Human1.07780206
110SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.07413624
111OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07396041
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06831130
113POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.06831130
114WT1_19549856_ChIP-ChIP_CCG9911_Human1.06760688
115FLI1_21867929_ChIP-Seq_TH2_Mouse1.06434112
116MYC_19829295_ChIP-Seq_ESCs_Human1.06074204
117* EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.05275653
118STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.05107619
119MYC_18940864_ChIP-ChIP_HL60_Human1.05077343
120P300_18555785_Chip-Seq_ESCs_Mouse1.04950629
121AR_20517297_ChIP-Seq_VCAP_Human1.04461650
122CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04454638
123* NCOR_22424771_ChIP-Seq_293T_Human1.04007267
124CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.03882400
125TBL1_22424771_ChIP-Seq_293T_Human1.03700043
126ZFP57_27257070_Chip-Seq_ESCs_Mouse1.03245103
127SOX2_20726797_ChIP-Seq_SW620_Human1.03118916
128SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.03095667
129TAL1_26923725_Chip-Seq_HPCs_Mouse1.03015873
130DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.02470853
131LXR_22158963_ChIP-Seq_LIVER_Mouse1.02260040
132EZH2_27304074_Chip-Seq_ESCs_Mouse1.01855008
133ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.01480550
134TCF4_23295773_ChIP-Seq_U87_Human1.00824998
135SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.00761909
136OCT4_21477851_ChIP-Seq_ESCs_Mouse0.99940743
137EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.99455956
138PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.98815271
139RUNX2_22187159_ChIP-Seq_PCA_Human0.98663859
140GATA4_25053715_ChIP-Seq_YYC3_Human0.98195712
141SMAD4_21741376_ChIP-Seq_EPCs_Human0.97820984
142SOX9_24532713_ChIP-Seq_HFSC_Mouse0.97755359
143ETV2_25802403_ChIP-Seq_MESCs_Mouse0.97720064
144EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.97631272
145OCT4_18555785_Chip-Seq_ESCs_Mouse0.97404105
146PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.97128097
147SOX2_21211035_ChIP-Seq_LN229_Gbm0.97075100
148ERA_21632823_ChIP-Seq_H3396_Human0.96790801
149BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.96416907
150FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.96195615
151FOXA1_25329375_ChIP-Seq_VCAP_Human0.96130446
152FOXA1_27270436_Chip-Seq_PROSTATE_Human0.96130446

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008004_abnormal_stomach_pH9.22384444
2MP0003136_yellow_coat_color5.46447343
3MP0002653_abnormal_ependyma_morphology4.10897354
4MP0002928_abnormal_bile_duct3.91944253
5MP0004133_heterotaxia3.25193516
6MP0004147_increased_porphyrin_level3.00540580
7MP0003195_calcinosis2.81194170
8MP0004043_abnormal_pH_regulation2.77176580
9MP0002735_abnormal_chemical_nociception2.66557037
10MP0005623_abnormal_meninges_morphology2.51772887
11MP0005379_endocrine/exocrine_gland_phen2.30620031
12MP0004885_abnormal_endolymph2.29242391
13MP0003646_muscle_fatigue2.21954069
14MP0001968_abnormal_touch/_nociception2.20480283
15MP0000613_abnormal_salivary_gland2.18538169
16MP0009780_abnormal_chondrocyte_physiolo2.18451252
17MP0008872_abnormal_physiological_respon2.14859488
18MP0008877_abnormal_DNA_methylation2.13821885
19MP0009046_muscle_twitch2.11109766
20MP0009745_abnormal_behavioral_response2.03796129
21MP0009384_cardiac_valve_regurgitation2.01416841
22MP0001958_emphysema1.95089383
23MP0005646_abnormal_pituitary_gland1.94565838
24MP0002102_abnormal_ear_morphology1.93278192
25MP0005645_abnormal_hypothalamus_physiol1.91685080
26MP0002160_abnormal_reproductive_system1.89445235
27MP0002909_abnormal_adrenal_gland1.89102790
28MP0002139_abnormal_hepatobiliary_system1.84196693
29MP0002638_abnormal_pupillary_reflex1.79867764
30MP0001944_abnormal_pancreas_morphology1.77925735
31MP0001177_atelectasis1.74291620
32MP0000569_abnormal_digit_pigmentation1.74279419
33MP0001486_abnormal_startle_reflex1.74253297
34MP0004742_abnormal_vestibular_system1.73554677
35MP0002272_abnormal_nervous_system1.68411393
36MP0002168_other_aberrant_phenotype1.66915055
37MP0002295_abnormal_pulmonary_circulatio1.65257930
38MP0002837_dystrophic_cardiac_calcinosis1.60738619
39MP0003937_abnormal_limbs/digits/tail_de1.59009681
40MP0005377_hearing/vestibular/ear_phenot1.58988665
41MP0003878_abnormal_ear_physiology1.58988665
42MP0002736_abnormal_nociception_after1.57153554
43MP0002249_abnormal_larynx_morphology1.56971422
44MP0001984_abnormal_olfaction1.56724571
45MP0002282_abnormal_trachea_morphology1.56382763
46MP0001970_abnormal_pain_threshold1.52079607
47MP0005647_abnormal_sex_gland1.51593687
48MP0002733_abnormal_thermal_nociception1.51146883
49MP0005389_reproductive_system_phenotype1.48410848
50MP0008875_abnormal_xenobiotic_pharmacok1.46147002
51MP0004782_abnormal_surfactant_physiolog1.44674821
52MP0003186_abnormal_redox_activity1.44127187
53MP0005220_abnormal_exocrine_pancreas1.43643904
54MP0005388_respiratory_system_phenotype1.41726094
55MP0002133_abnormal_respiratory_system1.41726094
56MP0004019_abnormal_vitamin_homeostasis1.36926994
57MP0002064_seizures1.36908590
58MP0002572_abnormal_emotion/affect_behav1.34483239
59MP0000427_abnormal_hair_cycle1.33920570
60MP0006276_abnormal_autonomic_nervous1.31995814
61MP0001765_abnormal_ion_homeostasis1.31651425
62MP0004142_abnormal_muscle_tone1.26155594
63MP0002557_abnormal_social/conspecific_i1.25209508
64MP0006072_abnormal_retinal_apoptosis1.24243619
65MP0003718_maternal_effect1.23647276
66MP0002234_abnormal_pharynx_morphology1.23604564
67MP0010386_abnormal_urinary_bladder1.22996379
68MP0006292_abnormal_olfactory_placode1.22849301
69MP0001879_abnormal_lymphatic_vessel1.22600801
70MP0002067_abnormal_sensory_capabilities1.21168542
71MP0003880_abnormal_central_pattern1.20956408
72MP0002089_abnormal_postnatal_growth/wei1.17760816
73MP0000372_irregular_coat_pigmentation1.16069889
74MP0005395_other_phenotype1.14966819
75MP0001873_stomach_inflammation1.14795729
76MP0003635_abnormal_synaptic_transmissio1.14618071
77MP0004924_abnormal_behavior1.13585594
78MP0005386_behavior/neurological_phenoty1.13585594
79MP0005248_abnormal_Harderian_gland1.12384720
80MP0002693_abnormal_pancreas_physiology1.11943164
81MP0002277_abnormal_respiratory_mucosa1.11830506
82MP0000428_abnormal_craniofacial_morphol1.10669492
83MP0000462_abnormal_digestive_system1.08469326
84MP0000470_abnormal_stomach_morphology1.08354403
85MP0005410_abnormal_fertilization1.06761854
86MP0003283_abnormal_digestive_organ1.06252933
87MP0000013_abnormal_adipose_tissue1.05979096
88MP0005174_abnormal_tail_pigmentation1.04453529
89MP0000383_abnormal_hair_follicle1.03112403
90MP0002063_abnormal_learning/memory/cond1.03062520
91MP0003634_abnormal_glial_cell1.03053165
92MP0000026_abnormal_inner_ear1.02963448
93MP0005195_abnormal_posterior_eye1.00096784
94MP0001270_distended_abdomen0.99793897
95MP0003698_abnormal_male_reproductive0.97141880
96MP0001963_abnormal_hearing_physiology0.97002870
97MP0001286_abnormal_eye_development0.96900411
98MP0005084_abnormal_gallbladder_morpholo0.96661909
99MP0003950_abnormal_plasma_membrane0.96018518
100MP0002896_abnormal_bone_mineralization0.95851365
101MP0001440_abnormal_grooming_behavior0.95714078
102MP0009250_abnormal_appendicular_skeleto0.94922946
103MP0003119_abnormal_digestive_system0.94747261
104MP0000163_abnormal_cartilage_morphology0.94382056
105MP0000049_abnormal_middle_ear0.94295710
106MP0002132_abnormal_respiratory_system0.93379978
107MP0001324_abnormal_eye_pigmentation0.92449140
108MP0004272_abnormal_basement_membrane0.91958063
109MP0003011_delayed_dark_adaptation0.91385097
110MP0001346_abnormal_lacrimal_gland0.90554417
111MP0010368_abnormal_lymphatic_system0.90162811
112MP0002876_abnormal_thyroid_physiology0.90037696
113MP0001529_abnormal_vocalization0.89970365
114MP0001293_anophthalmia0.88993324
115MP0001485_abnormal_pinna_reflex0.88433583
116MP0008775_abnormal_heart_ventricle0.88376536
117MP0001929_abnormal_gametogenesis0.88145661
118MP0004145_abnormal_muscle_electrophysio0.87386615
119MP0000230_abnormal_systemic_arterial0.87143348
120MP0002109_abnormal_limb_morphology0.86410260
121MP0005083_abnormal_biliary_tract0.86306865
122MP0004381_abnormal_hair_follicle0.85102861
123MP0002938_white_spotting0.84634598
124MP0005551_abnormal_eye_electrophysiolog0.83835756
125MP0000631_abnormal_neuroendocrine_gland0.83547563
126MP0003137_abnormal_impulse_conducting0.83203287
127MP0002115_abnormal_skeleton_extremities0.81974411
128MP0010678_abnormal_skin_adnexa0.81553959
129MP0004215_abnormal_myocardial_fiber0.81216191
130MP0002116_abnormal_craniofacial_bone0.80143320
131MP0002752_abnormal_somatic_nervous0.79685948
132MP0001756_abnormal_urination0.78893087
133MP0003890_abnormal_embryonic-extraembry0.78785584
134MP0001502_abnormal_circadian_rhythm0.78119125
135MP0005381_digestive/alimentary_phenotyp0.77619713
136MP0000778_abnormal_nervous_system0.76640593
137MP0000566_synostosis0.75862030
138MP0002229_neurodegeneration0.75542210
139MP0001664_abnormal_digestion0.75430167
140MP0009643_abnormal_urine_homeostasis0.75365134
141MP0002751_abnormal_autonomic_nervous0.75300161
142MP0001905_abnormal_dopamine_level0.75285992
143MP0001986_abnormal_taste_sensitivity0.74285900
144MP0003690_abnormal_glial_cell0.72892843
145MP0003755_abnormal_palate_morphology0.72738465
146MP0005408_hypopigmentation0.71854525
147MP0005636_abnormal_mineral_homeostasis0.71174845
148MP0001919_abnormal_reproductive_system0.70876469
149MP0003953_abnormal_hormone_level0.70537632
150MP0005253_abnormal_eye_physiology0.69975353
151MP0005167_abnormal_blood-brain_barrier0.68377419
152MP0002108_abnormal_muscle_morphology0.65588731
153MP0003045_fibrosis0.65421149
154MP0002138_abnormal_hepatobiliary_system0.64084717
155MP0001501_abnormal_sleep_pattern0.63972240
156MP0003943_abnormal_hepatobiliary_system0.63895598
157MP0000762_abnormal_tongue_morphology0.63247322
158MP0003942_abnormal_urinary_system0.61338220
159MP0005085_abnormal_gallbladder_physiolo0.61280133
160MP0002078_abnormal_glucose_homeostasis0.61249217
161MP0002734_abnormal_mechanical_nocicepti0.61004436
162MP0002136_abnormal_kidney_physiology0.60415888
163MP0001663_abnormal_digestive_system0.60035576
164MP0003938_abnormal_ear_development0.59933036
165MP0003252_abnormal_bile_duct0.59120586
166MP0001851_eye_inflammation0.56931419
167MP0002098_abnormal_vibrissa_morphology0.56779068

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)8.63841403
2Abnormal respiratory motile cilium morphology (HP:0005938)8.63841403
3Chronic bronchitis (HP:0004469)7.32703805
4Bronchiectasis (HP:0002110)6.05084783
5Dynein arm defect of respiratory motile cilia (HP:0012255)5.33846008
6Absent/shortened dynein arms (HP:0200106)5.33846008
7Pancreatic fibrosis (HP:0100732)4.84467702
8True hermaphroditism (HP:0010459)4.68972956
9Male infertility (HP:0003251)4.11507072
10Nasal polyposis (HP:0100582)3.95154564
11Occipital encephalocele (HP:0002085)3.94589486
12Birth length less than 3rd percentile (HP:0003561)3.52864257
13Abnormal biliary tract physiology (HP:0012439)3.51235368
14Bile duct proliferation (HP:0001408)3.51235368
15Pancreatic cysts (HP:0001737)3.42055538
16Abnormality of dentin (HP:0010299)3.38420921
17Infertility (HP:0000789)3.35335160
18Abnormality of the nasal mucosa (HP:0000433)3.31838717
19Bronchitis (HP:0012387)3.22553750
20Cystic liver disease (HP:0006706)3.21829739
21Tubulointerstitial nephritis (HP:0001970)3.17278158
22Type II lissencephaly (HP:0007260)3.12420442
23Recurrent sinusitis (HP:0011108)3.12174197
24Median cleft lip (HP:0000161)3.07035026
25Congenital stationary night blindness (HP:0007642)3.02505867
26Chronic sinusitis (HP:0011109)2.97159367
27Supernumerary spleens (HP:0009799)2.94287587
28Abnormality of the renal cortex (HP:0011035)2.93186830
29Hyperventilation (HP:0002883)2.90910284
30Gait imbalance (HP:0002141)2.72825861
31Congenital primary aphakia (HP:0007707)2.72173243
32Medial flaring of the eyebrow (HP:0010747)2.71605142
33Abnormality of permanent molar morphology (HP:0011071)2.71364345
34Abnormality of the dental root (HP:0006486)2.71364345
35Taurodontia (HP:0000679)2.71364345
36Postaxial foot polydactyly (HP:0001830)2.71281357
37Back pain (HP:0003418)2.64690357
38Abnormality of midbrain morphology (HP:0002418)2.63385268
39Molar tooth sign on MRI (HP:0002419)2.63385268
40Male pseudohermaphroditism (HP:0000037)2.58684108
41Aplasia/Hypoplasia of the tongue (HP:0010295)2.55843786
42Abnormality of molar (HP:0011077)2.55743096
43Abnormality of molar morphology (HP:0011070)2.55743096
44Chronic hepatic failure (HP:0100626)2.52014864
45Abnormality of the dental pulp (HP:0006479)2.50201615
46Congenital hepatic fibrosis (HP:0002612)2.48814719
47Nephrogenic diabetes insipidus (HP:0009806)2.40585279
48Genital tract atresia (HP:0001827)2.27660501
49Nephronophthisis (HP:0000090)2.27556528
50Decreased central vision (HP:0007663)2.26750704
51Large for gestational age (HP:0001520)2.25640980
52Abnormal rod and cone electroretinograms (HP:0008323)2.23012944
53Abolished electroretinogram (ERG) (HP:0000550)2.17412164
54Attenuation of retinal blood vessels (HP:0007843)2.14469513
55Chronic otitis media (HP:0000389)2.12617214
56Recurrent otitis media (HP:0000403)2.11230683
57Facial cleft (HP:0002006)2.09772894
58Abnormal drinking behavior (HP:0030082)2.08596955
59Polydipsia (HP:0001959)2.08596955
60Lissencephaly (HP:0001339)2.07821372
61Preaxial hand polydactyly (HP:0001177)2.06178629
62Progressive cerebellar ataxia (HP:0002073)2.04477263
63Poor coordination (HP:0002370)2.02682674
64Neonatal short-limb short stature (HP:0008921)2.01876667
65Broad-based gait (HP:0002136)2.01697361
66Pendular nystagmus (HP:0012043)2.01275203
67Protruding tongue (HP:0010808)2.01266931
68Short nail (HP:0001799)2.01232175
69Vaginal atresia (HP:0000148)2.01185955
70Abnormal respiratory motile cilium physiology (HP:0012261)12.5153957
71Abnormal ciliary motility (HP:0012262)12.1823888
72Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.2263949
73Rhinitis (HP:0012384)10.3987731
74Decreased circulating renin level (HP:0003351)1.99762843
75Abnormal umbilical cord blood vessels (HP:0011403)1.98486643
76Single umbilical artery (HP:0001195)1.98486643
77Abnormality of the fetal cardiovascular system (HP:0010948)1.98486643
78Broad distal phalanx of finger (HP:0009836)1.98175900
79Patellar aplasia (HP:0006443)1.98058434
80Congenital, generalized hypertrichosis (HP:0004540)1.97115209
81Inability to walk (HP:0002540)1.97066594
82Anencephaly (HP:0002323)1.96255909
83Furrowed tongue (HP:0000221)1.94420345
84Asplenia (HP:0001746)1.93330943
85Absent rod-and cone-mediated responses on ERG (HP:0007688)1.92048224
86Aplasia/Hypoplasia of the patella (HP:0006498)1.90690432
87Cerebellar dysplasia (HP:0007033)1.90386221
88Aplasia/Hypoplasia of the sternum (HP:0006714)1.90034048
89Breast hypoplasia (HP:0003187)1.89725715
90Microretrognathia (HP:0000308)1.88352207
91Chorioretinal atrophy (HP:0000533)1.86174340
92Tubulointerstitial abnormality (HP:0001969)1.85795706
93Gaze-evoked nystagmus (HP:0000640)1.84842549
94Abnormality of the renal medulla (HP:0100957)1.84731126
95Aplasia/Hypoplasia of the spleen (HP:0010451)1.83900476
96Abdominal situs inversus (HP:0003363)1.82497149
97Abnormality of abdominal situs (HP:0011620)1.82497149
98Increased corneal curvature (HP:0100692)1.81827149
99Keratoconus (HP:0000563)1.81827149
100Postaxial hand polydactyly (HP:0001162)1.77976858
101Fibular hypoplasia (HP:0003038)1.77205586
102Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.72659429
103Degeneration of the lateral corticospinal tracts (HP:0002314)1.72659429
104Aplasia/Hypoplasia of the lens (HP:0008063)1.72565177
105Polyuria (HP:0000103)1.71699685
106Hyperglycinuria (HP:0003108)1.71339784
107Optic nerve hypoplasia (HP:0000609)1.68752642
108Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.68278015
109Bony spicule pigmentary retinopathy (HP:0007737)1.67481696
110Concave nail (HP:0001598)1.66093950
111Stage 5 chronic kidney disease (HP:0003774)1.65477897
112Sclerocornea (HP:0000647)1.65418132
113Natal tooth (HP:0000695)1.64335608
114Absent speech (HP:0001344)1.62737785
115Progressive inability to walk (HP:0002505)1.61394802
116Fair hair (HP:0002286)1.61295925
117Scrotal hypoplasia (HP:0000046)1.60796258
118Anophthalmia (HP:0000528)1.58408028
119Retinitis pigmentosa (HP:0000510)1.57243125
120Dandy-Walker malformation (HP:0001305)1.56564360
121Aplasia/Hypoplasia of the tibia (HP:0005772)1.56348602
122Adrenal hypoplasia (HP:0000835)1.55431018
123Clumsiness (HP:0002312)1.54796025
124Renal cortical cysts (HP:0000803)1.53741585
125Tubular atrophy (HP:0000092)1.53410671
126Prominent nasal bridge (HP:0000426)1.52017384
127Sex reversal (HP:0012245)1.51436802
128Abnormal sex determination (HP:0012244)1.51436802
129Ventricular fibrillation (HP:0001663)1.50040933
130Hyperactive renin-angiotensin system (HP:0000841)1.49896065
131Arterial tortuosity (HP:0005116)1.48658900
132Oculomotor apraxia (HP:0000657)1.48260611
133Bifid tongue (HP:0010297)1.47443602
134Nephropathy (HP:0000112)1.47306321
135Genetic anticipation (HP:0003743)1.45686258
136Hypotelorism (HP:0000601)1.44205539
137Megalencephaly (HP:0001355)1.37205826
138Termporal pattern (HP:0011008)1.35940174
139Insidious onset (HP:0003587)1.35940174
140Epiphyseal dysplasia (HP:0002656)1.35187810
141Breech presentation (HP:0001623)1.34480432
142Aplasia involving bones of the extremities (HP:0009825)1.33862390
143Aplasia involving bones of the upper limbs (HP:0009823)1.33862390
144Aplasia of the phalanges of the hand (HP:0009802)1.33862390
145Abnormality of glycine metabolism (HP:0010895)1.32486161
146Abnormality of serine family amino acid metabolism (HP:0010894)1.32486161
147Hypodontia (HP:0000668)1.32261223
148Atelectasis (HP:0100750)1.31788426

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK159.58680493
2PNCK5.07288053
3GRK14.18102197
4ACVR1B4.09809975
5BMPR1B4.08513902
6CASK3.38230981
7MST42.90414938
8ADRBK22.79808852
9TLK12.70477190
10MAP3K92.62201102
11ZAK2.33182969
12LATS12.26575505
13DAPK22.14201506
14STK38L1.88507643
15TGFBR11.84818078
16CDC42BPA1.82294460
17MAP4K21.76106383
18PINK11.74497335
19FRK1.67421332
20MAP3K41.65211686
21WNK41.51894648
22SIK11.49402124
23INSRR1.47757874
24ERBB31.42482593
25MKNK21.41328455
26STK101.39021506
27STK391.31948608
28VRK11.31601848
29BCR1.30036128
30BMPR21.29923522
31PRKD31.27222536
32EEF2K1.24202903
33WEE11.22657198
34NTRK21.17639074
35OXSR11.17339492
36MAP3K21.15408729
37PRKCG1.14936261
38NEK21.13500289
39WNK31.11526798
40TRPM71.11418817
41MAP3K31.09260383
42LRRK21.06953752
43EPHA21.06397894
44PASK1.05851745
45CAMKK11.04189576
46SIK21.04176588
47PTK61.01146924
48CDK30.99332235
49PTK20.92520268
50NTRK30.91958764
51MAPKAPK50.90278202
52MAP2K70.90036508
53GSK3A0.89957848
54PAK30.89257448
55LATS20.88149504
56MARK10.87925678
57TNIK0.87405153
58PRKCE0.86976638
59HIPK20.84475579
60NLK0.81455306
61PLK40.79687045
62MAPK70.79393733
63MAP2K20.78021053
64TXK0.76782373
65ITK0.75023395
66EIF2AK30.72254656
67MAP2K60.72189522
68RPS6KA20.71987027
69PIK3CA0.71082855
70MAP3K70.70003772
71ROCK10.68803920
72ROCK20.64617703
73TIE10.64598341
74PRKAA20.64019959
75PIK3CG0.63932606
76NME10.63709083
77MUSK0.62733577
78LMTK20.62313962
79PLK20.61262483
80CAMK2A0.60186801
81DYRK20.60170676
82LIMK10.60160881
83CAMKK20.58487095
84STK240.58073858
85ARAF0.57003053
86PRKCI0.56981992
87NUAK10.56622030
88PRKG20.55768776
89CAMK10.54363771
90AURKA0.53641291
91TEC0.53378552
92MAPKAPK30.52919673
93MKNK10.52629992
94CSNK1G10.51071301
95CSNK1G20.50962132
96PAK20.50166717
97NEK60.49812837
98MAP2K10.49329036
99PKN10.49124770
100RPS6KB20.49113771
101DYRK1A0.48785368
102MAPK120.48475998
103IRAK10.47808161
104PHKG10.46948649
105PHKG20.46948649
106STK30.45872685
107RPS6KA50.44609040
108PRKACA0.43793486
109TRIM280.43023971
110CHUK0.41160034
111TGFBR20.40642378
112PRKACG0.39762101
113EPHB10.38777712
114MAP2K40.38356633
115JAK10.37691620
116GRK70.36640986
117BCKDK0.36494448
118PTK2B0.35937930
119PRKG10.35494320
120WNK10.35160137
121MAPK130.35033001
122STK110.34070485
123CAMK2B0.33987996
124RIPK10.33605988
125ADRBK10.33567750
126MAPK100.32360739
127PRKCZ0.32272351
128MAPKAPK20.32166161
129CAMK1D0.32027261
130BRSK20.31835749
131NEK90.31659690
132BRSK10.31533843
133TAOK30.31405817
134CAMK2D0.31331462
135ERBB40.31209449
136EPHA40.31017722
137DMPK0.30986446
138ABL10.30899782
139PRKAA10.30596029
140PLK30.30358553
141CSNK1A10.30296288
142KIT0.30254892
143MELK0.29685256
144MAPK40.29088161
145PRKCQ0.28147185
146PRKDC0.27717280
147PRKCA0.27491238
148PRKD20.27265167
149PLK10.27190094
150ERBB20.27078794
151EIF2AK20.26637443
152IKBKB0.26595165
153CAMK1G0.26127187
154TSSK60.26002896
155SRC0.25810880
156CSNK1G30.25361938
157CAMK40.22954586

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000725.47152550
2Maturity onset diabetes of the young_Homo sapiens_hsa049504.32105279
3Vitamin B6 metabolism_Homo sapiens_hsa007503.22120510
4Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.87340443
5Nicotine addiction_Homo sapiens_hsa050332.72938574
6Huntingtons disease_Homo sapiens_hsa050162.58020975
7Ovarian steroidogenesis_Homo sapiens_hsa049132.50344271
8Butanoate metabolism_Homo sapiens_hsa006502.45206108
9Sulfur metabolism_Homo sapiens_hsa009202.45070660
10Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.24681567
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.02998169
12Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.87743058
13Insulin secretion_Homo sapiens_hsa049111.84352231
14Protein export_Homo sapiens_hsa030601.83503371
15ABC transporters_Homo sapiens_hsa020101.79201913
16Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.74036944
17Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.71726738
18Tyrosine metabolism_Homo sapiens_hsa003501.68080237
19Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.65634323
20Propanoate metabolism_Homo sapiens_hsa006401.65303723
21Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.58982539
22Glutathione metabolism_Homo sapiens_hsa004801.58641896
23PPAR signaling pathway_Homo sapiens_hsa033201.57571154
24Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.55779295
25Phenylalanine metabolism_Homo sapiens_hsa003601.53785491
26Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.52768331
27Circadian rhythm_Homo sapiens_hsa047101.50412237
28Histidine metabolism_Homo sapiens_hsa003401.47945253
29Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.47579724
30Sphingolipid metabolism_Homo sapiens_hsa006001.33661394
31Mineral absorption_Homo sapiens_hsa049781.28508229
32Hippo signaling pathway_Homo sapiens_hsa043901.25740971
33Fanconi anemia pathway_Homo sapiens_hsa034601.24878467
34Serotonergic synapse_Homo sapiens_hsa047261.22233871
35Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.22103990
36Cocaine addiction_Homo sapiens_hsa050301.21004749
37Pentose and glucuronate interconversions_Homo sapiens_hsa000401.20893450
38Homologous recombination_Homo sapiens_hsa034401.16006968
39Glutamatergic synapse_Homo sapiens_hsa047241.15772912
40Thyroid hormone synthesis_Homo sapiens_hsa049181.15600672
41GABAergic synapse_Homo sapiens_hsa047271.14304481
42Gastric acid secretion_Homo sapiens_hsa049711.13483360
43Morphine addiction_Homo sapiens_hsa050321.13054820
44Tryptophan metabolism_Homo sapiens_hsa003801.12086525
45Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.11044837
46Retinol metabolism_Homo sapiens_hsa008301.09261109
47Arachidonic acid metabolism_Homo sapiens_hsa005901.08126155
48Chemical carcinogenesis_Homo sapiens_hsa052041.07884208
49Protein digestion and absorption_Homo sapiens_hsa049741.05248806
50Intestinal immune network for IgA production_Homo sapiens_hsa046721.04026170
51Cardiac muscle contraction_Homo sapiens_hsa042601.02142729
52Basal transcription factors_Homo sapiens_hsa030221.01951444
53Parkinsons disease_Homo sapiens_hsa050121.01423942
54Calcium signaling pathway_Homo sapiens_hsa040201.00200476
55Ether lipid metabolism_Homo sapiens_hsa005650.99430775
56Tight junction_Homo sapiens_hsa045300.98280689
57Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.97903064
58Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.96107392
59Primary bile acid biosynthesis_Homo sapiens_hsa001200.92877155
60Peroxisome_Homo sapiens_hsa041460.89782823
61Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88934363
62Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.87720152
63Selenocompound metabolism_Homo sapiens_hsa004500.87237891
64RNA polymerase_Homo sapiens_hsa030200.84327268
65Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81854010
66Amphetamine addiction_Homo sapiens_hsa050310.80156352
67Prolactin signaling pathway_Homo sapiens_hsa049170.80057365
68Vitamin digestion and absorption_Homo sapiens_hsa049770.79348758
69Aldosterone synthesis and secretion_Homo sapiens_hsa049250.78579342
70Fatty acid elongation_Homo sapiens_hsa000620.77793075
71Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.75801323
72Starch and sucrose metabolism_Homo sapiens_hsa005000.73872690
73Olfactory transduction_Homo sapiens_hsa047400.72041567
74Alzheimers disease_Homo sapiens_hsa050100.70937277
75Dorso-ventral axis formation_Homo sapiens_hsa043200.70619861
76GnRH signaling pathway_Homo sapiens_hsa049120.70531943
77Regulation of autophagy_Homo sapiens_hsa041400.69894507
78Glycerolipid metabolism_Homo sapiens_hsa005610.69849444
79Estrogen signaling pathway_Homo sapiens_hsa049150.67979670
80Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.67741127
81Bile secretion_Homo sapiens_hsa049760.67210241
82Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.66744801
83Purine metabolism_Homo sapiens_hsa002300.66109488
84ECM-receptor interaction_Homo sapiens_hsa045120.65892115
85Fatty acid biosynthesis_Homo sapiens_hsa000610.65671294
86cGMP-PKG signaling pathway_Homo sapiens_hsa040220.61993545
87TGF-beta signaling pathway_Homo sapiens_hsa043500.61669696
88Wnt signaling pathway_Homo sapiens_hsa043100.60856409
89Hedgehog signaling pathway_Homo sapiens_hsa043400.59894006
90Prion diseases_Homo sapiens_hsa050200.59510431
91Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.59453069
92cAMP signaling pathway_Homo sapiens_hsa040240.59346201
93RNA degradation_Homo sapiens_hsa030180.59219064
94Asthma_Homo sapiens_hsa053100.59043873
95Dopaminergic synapse_Homo sapiens_hsa047280.58601735
96Carbohydrate digestion and absorption_Homo sapiens_hsa049730.57580115
97Long-term depression_Homo sapiens_hsa047300.57534810
98Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.56168604
99Vibrio cholerae infection_Homo sapiens_hsa051100.56076078
100Phototransduction_Homo sapiens_hsa047440.55137471
101Basal cell carcinoma_Homo sapiens_hsa052170.54871527
102Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.54725791
103Nitrogen metabolism_Homo sapiens_hsa009100.53831632
104Fat digestion and absorption_Homo sapiens_hsa049750.50770384
105Nucleotide excision repair_Homo sapiens_hsa034200.48765542
106Complement and coagulation cascades_Homo sapiens_hsa046100.47945219
107Rheumatoid arthritis_Homo sapiens_hsa053230.47707871
108Arginine and proline metabolism_Homo sapiens_hsa003300.47421402
109alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.46862264
110Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.46219244
111Melanogenesis_Homo sapiens_hsa049160.45745978
112beta-Alanine metabolism_Homo sapiens_hsa004100.44220329
113Type I diabetes mellitus_Homo sapiens_hsa049400.43989682
114Metabolic pathways_Homo sapiens_hsa011000.43989338
115Pancreatic secretion_Homo sapiens_hsa049720.43774790
116Glycerophospholipid metabolism_Homo sapiens_hsa005640.42848534
117SNARE interactions in vesicular transport_Homo sapiens_hsa041300.42460650
118Oxytocin signaling pathway_Homo sapiens_hsa049210.41770699
119Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.41523033
120Fatty acid degradation_Homo sapiens_hsa000710.41251224
121Circadian entrainment_Homo sapiens_hsa047130.40364527
122Linoleic acid metabolism_Homo sapiens_hsa005910.39997315
123Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.39982880
124One carbon pool by folate_Homo sapiens_hsa006700.39860451
125Vascular smooth muscle contraction_Homo sapiens_hsa042700.39124553
126Taste transduction_Homo sapiens_hsa047420.38447684
127Salivary secretion_Homo sapiens_hsa049700.37832674
128Collecting duct acid secretion_Homo sapiens_hsa049660.36855633
129Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.35179289
130Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.33763417
131Cholinergic synapse_Homo sapiens_hsa047250.32898151
132Steroid hormone biosynthesis_Homo sapiens_hsa001400.32265958
133Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.31236664
134Gap junction_Homo sapiens_hsa045400.30871560
135Phagosome_Homo sapiens_hsa041450.30866078
136Oxidative phosphorylation_Homo sapiens_hsa001900.30182310
137Galactose metabolism_Homo sapiens_hsa000520.29199885
138Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.28967111
139Caffeine metabolism_Homo sapiens_hsa002320.27933185

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