

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein refolding (GO:0042026) | 8.08840749 |
| 2 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 7.02744065 |
| 3 | negative regulation of inclusion body assembly (GO:0090084) | 6.22128226 |
| 4 | cullin deneddylation (GO:0010388) | 5.81412187 |
| 5 | protein deneddylation (GO:0000338) | 5.34309962 |
| 6 | nuclear pore organization (GO:0006999) | 4.89282399 |
| 7 | maturation of 5.8S rRNA (GO:0000460) | 4.77321894 |
| 8 | DNA damage response, detection of DNA damage (GO:0042769) | 4.67806153 |
| 9 | ribosome assembly (GO:0042255) | 4.48781655 |
| 10 | succinate metabolic process (GO:0006105) | 4.43924619 |
| 11 | nuclear pore complex assembly (GO:0051292) | 4.36970461 |
| 12 | GMP metabolic process (GO:0046037) | 4.35560338 |
| 13 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.24763176 |
| 14 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.24763176 |
| 15 | regulation of translational termination (GO:0006449) | 4.17692927 |
| 16 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.92313368 |
| 17 | oxaloacetate metabolic process (GO:0006107) | 3.90506775 |
| 18 | zinc ion transmembrane transport (GO:0071577) | 3.87471778 |
| 19 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.84442024 |
| 20 | DNA strand elongation (GO:0022616) | 3.84241459 |
| 21 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.84145912 |
| 22 | ubiquinone biosynthetic process (GO:0006744) | 3.82599640 |
| 23 | proteasome assembly (GO:0043248) | 3.79217295 |
| 24 | deoxyribonucleotide biosynthetic process (GO:0009263) | 3.77880641 |
| 25 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.74379699 |
| 26 | formation of translation preinitiation complex (GO:0001731) | 3.66565541 |
| 27 | valine metabolic process (GO:0006573) | 3.59900865 |
| 28 | ubiquinone metabolic process (GO:0006743) | 3.56032741 |
| 29 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.55832749 |
| 30 | de novo protein folding (GO:0006458) | 3.55527194 |
| 31 | regulation of inclusion body assembly (GO:0090083) | 3.52523864 |
| 32 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.52132351 |
| 33 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.52132351 |
| 34 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.50542921 |
| 35 | chromatin remodeling at centromere (GO:0031055) | 3.48844125 |
| 36 | de novo posttranslational protein folding (GO:0051084) | 3.47102960 |
| 37 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.45993971 |
| 38 | DNA replication initiation (GO:0006270) | 3.45160186 |
| 39 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.43282353 |
| 40 | negative regulation of ligase activity (GO:0051352) | 3.43282353 |
| 41 | regulation of coenzyme metabolic process (GO:0051196) | 3.42772412 |
| 42 | regulation of cofactor metabolic process (GO:0051193) | 3.42772412 |
| 43 | DNA topological change (GO:0006265) | 3.41170828 |
| 44 | pore complex assembly (GO:0046931) | 3.40327001 |
| 45 | CENP-A containing nucleosome assembly (GO:0034080) | 3.39112116 |
| 46 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.33062732 |
| 47 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.30223937 |
| 48 | non-recombinational repair (GO:0000726) | 3.30223937 |
| 49 | DNA replication checkpoint (GO:0000076) | 3.29120057 |
| 50 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 3.25535919 |
| 51 | branched-chain amino acid metabolic process (GO:0009081) | 3.23983992 |
| 52 | NADH dehydrogenase complex assembly (GO:0010257) | 3.22631038 |
| 53 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.22631038 |
| 54 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.22631038 |
| 55 | tRNA aminoacylation for protein translation (GO:0006418) | 3.19893684 |
| 56 | protein K11-linked ubiquitination (GO:0070979) | 3.18192857 |
| 57 | amino acid activation (GO:0043038) | 3.13161496 |
| 58 | tRNA aminoacylation (GO:0043039) | 3.13161496 |
| 59 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.11322330 |
| 60 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.11322330 |
| 61 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.11322330 |
| 62 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.10561857 |
| 63 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.10561857 |
| 64 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.09033212 |
| 65 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.09033212 |
| 66 | ribosome biogenesis (GO:0042254) | 3.08522987 |
| 67 | genitalia morphogenesis (GO:0035112) | 3.08485895 |
| 68 | mitotic spindle checkpoint (GO:0071174) | 3.08203186 |
| 69 | quinone biosynthetic process (GO:1901663) | 3.07426089 |
| 70 | regulation of mitochondrial translation (GO:0070129) | 3.07101260 |
| 71 | mitotic nuclear envelope disassembly (GO:0007077) | 3.05114159 |
| 72 | telomere maintenance via recombination (GO:0000722) | 3.03402078 |
| 73 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.02478763 |
| 74 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.01709885 |
| 75 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.01709885 |
| 76 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.99745180 |
| 77 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.97581956 |
| 78 | DNA unwinding involved in DNA replication (GO:0006268) | 2.97342565 |
| 79 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.96021905 |
| 80 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.94953638 |
| 81 | AMP metabolic process (GO:0046033) | 2.94931137 |
| 82 | spindle checkpoint (GO:0031577) | 2.94877494 |
| 83 | branched-chain amino acid catabolic process (GO:0009083) | 2.93879035 |
| 84 | regulation of sulfur metabolic process (GO:0042762) | 2.92598187 |
| 85 | regulation of translational fidelity (GO:0006450) | 2.91439904 |
| 86 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 2.90782627 |
| 87 | 7-methylguanosine mRNA capping (GO:0006370) | 2.90373811 |
| 88 | negative regulation of striated muscle cell apoptotic process (GO:0010664) | 2.90034602 |
| 89 | spliceosomal snRNP assembly (GO:0000387) | 2.90028509 |
| 90 | positive regulation of transcription regulatory region DNA binding (GO:2000679) | 2.89133321 |
| 91 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.88117617 |
| 92 | termination of RNA polymerase III transcription (GO:0006386) | 2.88117617 |
| 93 | IMP biosynthetic process (GO:0006188) | 2.85260454 |
| 94 | membrane disassembly (GO:0030397) | 2.83610695 |
| 95 | nuclear envelope disassembly (GO:0051081) | 2.83610695 |
| 96 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.83528407 |
| 97 | 7-methylguanosine RNA capping (GO:0009452) | 2.83511318 |
| 98 | RNA capping (GO:0036260) | 2.83511318 |
| 99 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.81919337 |
| 100 | histone exchange (GO:0043486) | 2.77993236 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.83507709 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.07536958 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.64743048 |
| 4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.25884545 |
| 5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.69055730 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.57636504 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.46873306 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.23797387 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.13422314 |
| 10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.97600506 |
| 11 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.79555983 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.79402094 |
| 13 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.74003282 |
| 14 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.70476001 |
| 15 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.63889952 |
| 16 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.52115469 |
| 17 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.51124344 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.48156004 |
| 19 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.46144487 |
| 20 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.35677744 |
| 21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.34479212 |
| 22 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.33847571 |
| 23 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.32896279 |
| 24 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.29221401 |
| 25 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.28846703 |
| 26 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.26163322 |
| 27 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.25481820 |
| 28 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.24502341 |
| 29 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.19904311 |
| 30 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.18373891 |
| 31 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.13981102 |
| 32 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.04557183 |
| 33 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 2.03000404 |
| 34 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.01934013 |
| 35 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.01390071 |
| 36 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.99240485 |
| 37 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.91258154 |
| 38 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.90818948 |
| 39 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.86773251 |
| 40 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.83072547 |
| 41 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.79850984 |
| 42 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.75245273 |
| 43 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.67429681 |
| 44 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.64363644 |
| 45 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.59876423 |
| 46 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.58809637 |
| 47 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.58456500 |
| 48 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.57830768 |
| 49 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.54819055 |
| 50 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.54188851 |
| 51 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.51640958 |
| 52 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.39404969 |
| 53 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.24593761 |
| 54 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.23964766 |
| 55 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.21625317 |
| 56 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.20952365 |
| 57 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.19942299 |
| 58 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.19107567 |
| 59 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.18994359 |
| 60 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.18230925 |
| 61 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.18038810 |
| 62 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.16505555 |
| 63 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.13955117 |
| 64 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.13857755 |
| 65 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.13560711 |
| 66 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.13320499 |
| 67 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.11290882 |
| 68 | EWS_26573619_Chip-Seq_HEK293_Human | 1.10749219 |
| 69 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.10369928 |
| 70 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.05026162 |
| 71 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.02736157 |
| 72 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.00201809 |
| 73 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.99401061 |
| 74 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.98782578 |
| 75 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.98223479 |
| 76 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.97692618 |
| 77 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93802752 |
| 78 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.93449938 |
| 79 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.90438133 |
| 80 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.87718284 |
| 81 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.85719635 |
| 82 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.84729125 |
| 83 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.84694208 |
| 84 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.83293736 |
| 85 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.82950079 |
| 86 | VDR_22108803_ChIP-Seq_LS180_Human | 0.81769063 |
| 87 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.78588382 |
| 88 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.77293328 |
| 89 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.77109099 |
| 90 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.76487358 |
| 91 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.74998233 |
| 92 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.73165448 |
| 93 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.71680221 |
| 94 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.69046615 |
| 95 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.68046934 |
| 96 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.66349475 |
| 97 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.65861303 |
| 98 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.63689703 |
| 99 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.61268615 |
| 100 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.60754629 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 3.87471160 |
| 2 | MP0009697_abnormal_copulation | 3.72083868 |
| 3 | MP0008058_abnormal_DNA_repair | 3.70642688 |
| 4 | MP0003806_abnormal_nucleotide_metabolis | 3.48527780 |
| 5 | MP0006292_abnormal_olfactory_placode | 3.35173517 |
| 6 | MP0004957_abnormal_blastocyst_morpholog | 3.24647496 |
| 7 | MP0003693_abnormal_embryo_hatching | 2.91974322 |
| 8 | MP0003111_abnormal_nucleus_morphology | 2.86345018 |
| 9 | MP0002102_abnormal_ear_morphology | 2.75080026 |
| 10 | MP0003077_abnormal_cell_cycle | 2.71156981 |
| 11 | MP0003221_abnormal_cardiomyocyte_apopto | 2.68678830 |
| 12 | MP0003718_maternal_effect | 2.61524816 |
| 13 | MP0002822_catalepsy | 2.54440853 |
| 14 | MP0001661_extended_life_span | 2.41785421 |
| 15 | MP0008932_abnormal_embryonic_tissue | 2.26747264 |
| 16 | MP0001529_abnormal_vocalization | 2.21184554 |
| 17 | MP0005187_abnormal_penis_morphology | 2.17568170 |
| 18 | MP0008057_abnormal_DNA_replication | 2.08494297 |
| 19 | MP0001730_embryonic_growth_arrest | 1.90577118 |
| 20 | MP0000749_muscle_degeneration | 1.87298189 |
| 21 | MP0003122_maternal_imprinting | 1.85459419 |
| 22 | MP0003786_premature_aging | 1.84637572 |
| 23 | MP0003121_genomic_imprinting | 1.78755559 |
| 24 | MP0002132_abnormal_respiratory_system | 1.74453064 |
| 25 | MP0008007_abnormal_cellular_replicative | 1.73413312 |
| 26 | MP0002938_white_spotting | 1.68467201 |
| 27 | MP0006035_abnormal_mitochondrial_morpho | 1.65995682 |
| 28 | MP0003890_abnormal_embryonic-extraembry | 1.62651821 |
| 29 | MP0001697_abnormal_embryo_size | 1.58771156 |
| 30 | MP0003937_abnormal_limbs/digits/tail_de | 1.56061333 |
| 31 | MP0009672_abnormal_birth_weight | 1.51158162 |
| 32 | MP0001293_anophthalmia | 1.51006353 |
| 33 | MP0004147_increased_porphyrin_level | 1.50656549 |
| 34 | MP0003567_abnormal_fetal_cardiomyocyte | 1.47844845 |
| 35 | MP0005380_embryogenesis_phenotype | 1.47473563 |
| 36 | MP0001672_abnormal_embryogenesis/_devel | 1.47473563 |
| 37 | MP0000350_abnormal_cell_proliferation | 1.41917705 |
| 38 | MP0000358_abnormal_cell_content/ | 1.39230785 |
| 39 | MP0000428_abnormal_craniofacial_morphol | 1.37726016 |
| 40 | MP0003828_pulmonary_edema | 1.34201426 |
| 41 | MP0008995_early_reproductive_senescence | 1.32604548 |
| 42 | MP0008877_abnormal_DNA_methylation | 1.31163076 |
| 43 | MP0003984_embryonic_growth_retardation | 1.26674306 |
| 44 | MP0003315_abnormal_perineum_morphology | 1.24934331 |
| 45 | MP0006036_abnormal_mitochondrial_physio | 1.22908593 |
| 46 | MP0002080_prenatal_lethality | 1.22492010 |
| 47 | MP0001727_abnormal_embryo_implantation | 1.22460764 |
| 48 | MP0002210_abnormal_sex_determination | 1.20712027 |
| 49 | MP0002088_abnormal_embryonic_growth/wei | 1.20586417 |
| 50 | MP0002084_abnormal_developmental_patter | 1.19182586 |
| 51 | MP0005645_abnormal_hypothalamus_physiol | 1.17050076 |
| 52 | MP0004197_abnormal_fetal_growth/weight/ | 1.16642908 |
| 53 | MP0001929_abnormal_gametogenesis | 1.13795957 |
| 54 | MP0005636_abnormal_mineral_homeostasis | 1.13209022 |
| 55 | MP0000372_irregular_coat_pigmentation | 1.10468708 |
| 56 | MP0002396_abnormal_hematopoietic_system | 1.08356188 |
| 57 | MP0001286_abnormal_eye_development | 1.06965021 |
| 58 | MP0003123_paternal_imprinting | 1.04940466 |
| 59 | MP0002111_abnormal_tail_morphology | 1.03433310 |
| 60 | MP0001145_abnormal_male_reproductive | 1.02826921 |
| 61 | MP0002085_abnormal_embryonic_tissue | 1.01628883 |
| 62 | MP0000490_abnormal_crypts_of | 1.00197106 |
| 63 | MP0001915_intracranial_hemorrhage | 0.99517783 |
| 64 | MP0001764_abnormal_homeostasis | 0.99107577 |
| 65 | MP0000647_abnormal_sebaceous_gland | 0.98414904 |
| 66 | MP0000653_abnormal_sex_gland | 0.96871106 |
| 67 | MP0010307_abnormal_tumor_latency | 0.96368579 |
| 68 | MP0002086_abnormal_extraembryonic_tissu | 0.94675782 |
| 69 | MP0003119_abnormal_digestive_system | 0.92525613 |
| 70 | MP0002160_abnormal_reproductive_system | 0.91220979 |
| 71 | MP0000313_abnormal_cell_death | 0.89532980 |
| 72 | MP0009703_decreased_birth_body | 0.88720730 |
| 73 | MP0003698_abnormal_male_reproductive | 0.88674698 |
| 74 | MP0001849_ear_inflammation | 0.86428310 |
| 75 | MP0001986_abnormal_taste_sensitivity | 0.86131060 |
| 76 | MP0000631_abnormal_neuroendocrine_gland | 0.85144441 |
| 77 | MP0001299_abnormal_eye_distance/ | 0.85112578 |
| 78 | MP0002697_abnormal_eye_size | 0.84855503 |
| 79 | MP0003938_abnormal_ear_development | 0.83032828 |
| 80 | MP0006072_abnormal_retinal_apoptosis | 0.82459544 |
| 81 | MP0002233_abnormal_nose_morphology | 0.80775002 |
| 82 | MP0006054_spinal_hemorrhage | 0.80666018 |
| 83 | MP0002638_abnormal_pupillary_reflex | 0.75255213 |
| 84 | MP0002751_abnormal_autonomic_nervous | 0.75201250 |
| 85 | MP0005220_abnormal_exocrine_pancreas | 0.73765672 |
| 86 | MP0010234_abnormal_vibrissa_follicle | 0.73418976 |
| 87 | MP0000569_abnormal_digit_pigmentation | 0.73017313 |
| 88 | MP0002876_abnormal_thyroid_physiology | 0.71916472 |
| 89 | MP0002161_abnormal_fertility/fecundity | 0.69114042 |
| 90 | MP0002269_muscular_atrophy | 0.68919171 |
| 91 | MP0005647_abnormal_sex_gland | 0.68585389 |
| 92 | MP0010630_abnormal_cardiac_muscle | 0.67767077 |
| 93 | MP0005253_abnormal_eye_physiology | 0.67702271 |
| 94 | MP0005391_vision/eye_phenotype | 0.63811501 |
| 95 | MP0002282_abnormal_trachea_morphology | 0.63650202 |
| 96 | MP0005451_abnormal_body_composition | 0.62221161 |
| 97 | MP0000613_abnormal_salivary_gland | 0.61907656 |
| 98 | MP0005395_other_phenotype | 0.61628447 |
| 99 | MP0000639_abnormal_adrenal_gland | 0.60923428 |
| 100 | MP0005334_abnormal_fat_pad | 0.59077101 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased serum pyruvate (HP:0003542) | 5.80001524 |
| 2 | Abnormality of glycolysis (HP:0004366) | 5.31220173 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.56184095 |
| 4 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.55649639 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.53234593 |
| 6 | Chromsome breakage (HP:0040012) | 4.34261395 |
| 7 | Diaphragmatic weakness (HP:0009113) | 4.04797832 |
| 8 | Pendular nystagmus (HP:0012043) | 3.99122543 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.85452348 |
| 10 | Acute encephalopathy (HP:0006846) | 3.78879566 |
| 11 | Cerebral edema (HP:0002181) | 3.68559146 |
| 12 | Abnormality of methionine metabolism (HP:0010901) | 3.54646438 |
| 13 | Increased CSF lactate (HP:0002490) | 3.38508889 |
| 14 | Meckel diverticulum (HP:0002245) | 3.24033710 |
| 15 | Abnormality of the ileum (HP:0001549) | 3.10127233 |
| 16 | Mitochondrial inheritance (HP:0001427) | 3.07548988 |
| 17 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.93147771 |
| 18 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.93147771 |
| 19 | Exercise intolerance (HP:0003546) | 2.87001202 |
| 20 | Absent radius (HP:0003974) | 2.84420851 |
| 21 | Increased serum lactate (HP:0002151) | 2.76990552 |
| 22 | Septo-optic dysplasia (HP:0100842) | 2.73023519 |
| 23 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.66059633 |
| 24 | Absent forearm bone (HP:0003953) | 2.64733579 |
| 25 | Aplasia involving forearm bones (HP:0009822) | 2.64733579 |
| 26 | Hepatocellular necrosis (HP:0001404) | 2.62536389 |
| 27 | Axonal loss (HP:0003447) | 2.58573097 |
| 28 | Abnormality of the preputium (HP:0100587) | 2.57672697 |
| 29 | Microvesicular hepatic steatosis (HP:0001414) | 2.57465391 |
| 30 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.54814066 |
| 31 | Abnormality of alanine metabolism (HP:0010916) | 2.54814066 |
| 32 | Hyperalaninemia (HP:0003348) | 2.54814066 |
| 33 | Lactic acidosis (HP:0003128) | 2.54387598 |
| 34 | Duplicated collecting system (HP:0000081) | 2.53852068 |
| 35 | Unilateral renal agenesis (HP:0000122) | 2.50517366 |
| 36 | Hepatic necrosis (HP:0002605) | 2.46995487 |
| 37 | Reticulocytopenia (HP:0001896) | 2.45627889 |
| 38 | Abnormality of the anterior horn cell (HP:0006802) | 2.43679926 |
| 39 | Degeneration of anterior horn cells (HP:0002398) | 2.43679926 |
| 40 | Progressive external ophthalmoplegia (HP:0000590) | 2.43585520 |
| 41 | Type I transferrin isoform profile (HP:0003642) | 2.42603855 |
| 42 | Submucous cleft hard palate (HP:0000176) | 2.39797131 |
| 43 | Acanthocytosis (HP:0001927) | 2.39385133 |
| 44 | Abnormality of chromosome stability (HP:0003220) | 2.38498883 |
| 45 | Median cleft lip (HP:0000161) | 2.29427515 |
| 46 | Triphalangeal thumb (HP:0001199) | 2.25995000 |
| 47 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.20190835 |
| 48 | X-linked dominant inheritance (HP:0001423) | 2.19971940 |
| 49 | Birth length less than 3rd percentile (HP:0003561) | 2.19845169 |
| 50 | Supernumerary spleens (HP:0009799) | 2.19552216 |
| 51 | Abnormality of the renal collecting system (HP:0004742) | 2.18830964 |
| 52 | Leukodystrophy (HP:0002415) | 2.18105960 |
| 53 | Respiratory failure (HP:0002878) | 2.18001965 |
| 54 | Optic disc pallor (HP:0000543) | 2.16747809 |
| 55 | High anterior hairline (HP:0009890) | 2.15681693 |
| 56 | Ragged-red muscle fibers (HP:0003200) | 2.14586630 |
| 57 | Increased hepatocellular lipid droplets (HP:0006565) | 2.13556577 |
| 58 | Increased intramyocellular lipid droplets (HP:0012240) | 2.09874045 |
| 59 | Small intestinal stenosis (HP:0012848) | 2.05761867 |
| 60 | Duodenal stenosis (HP:0100867) | 2.05761867 |
| 61 | Lipid accumulation in hepatocytes (HP:0006561) | 2.01924976 |
| 62 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.00573131 |
| 63 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.00179912 |
| 64 | Ectopic kidney (HP:0000086) | 1.99581780 |
| 65 | Hypobetalipoproteinemia (HP:0003563) | 1.97763026 |
| 66 | Abnormality of the duodenum (HP:0002246) | 1.94935379 |
| 67 | Alacrima (HP:0000522) | 1.94436296 |
| 68 | Abnormality of DNA repair (HP:0003254) | 1.94369729 |
| 69 | Cerebral hypomyelination (HP:0006808) | 1.93853940 |
| 70 | Absent thumb (HP:0009777) | 1.92968945 |
| 71 | Nasal speech (HP:0001611) | 1.90130719 |
| 72 | Progressive muscle weakness (HP:0003323) | 1.90051626 |
| 73 | Decreased lacrimation (HP:0000633) | 1.89105853 |
| 74 | Abnormal protein glycosylation (HP:0012346) | 1.88904862 |
| 75 | Abnormal glycosylation (HP:0012345) | 1.88904862 |
| 76 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.88904862 |
| 77 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.88904862 |
| 78 | Proximal tubulopathy (HP:0000114) | 1.86357391 |
| 79 | Tubulointerstitial nephritis (HP:0001970) | 1.85755561 |
| 80 | Posterior subcapsular cataract (HP:0007787) | 1.85065262 |
| 81 | Methylmalonic acidemia (HP:0002912) | 1.85017644 |
| 82 | Abnormal gallbladder physiology (HP:0012438) | 1.84110080 |
| 83 | Cholecystitis (HP:0001082) | 1.84110080 |
| 84 | Embryonal renal neoplasm (HP:0011794) | 1.82809029 |
| 85 | Renal agenesis (HP:0000104) | 1.82154147 |
| 86 | Abnormality of the carotid arteries (HP:0005344) | 1.79716205 |
| 87 | Abnormal number of incisors (HP:0011064) | 1.79661755 |
| 88 | Duplication of thumb phalanx (HP:0009942) | 1.76605993 |
| 89 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.76563415 |
| 90 | Abnormal lung lobation (HP:0002101) | 1.75691271 |
| 91 | Bifid tongue (HP:0010297) | 1.75211326 |
| 92 | Ureteral duplication (HP:0000073) | 1.75181409 |
| 93 | Dysphonia (HP:0001618) | 1.74296655 |
| 94 | Increased muscle lipid content (HP:0009058) | 1.73595763 |
| 95 | Lethargy (HP:0001254) | 1.73306814 |
| 96 | Myelodysplasia (HP:0002863) | 1.72938971 |
| 97 | Neuroblastic tumors (HP:0004376) | 1.71571845 |
| 98 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 1.71571845 |
| 99 | Neuroblastoma (HP:0003006) | 1.71571845 |
| 100 | Primitive neuroectodermal tumor (HP:0030065) | 1.71571845 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAPKAPK5 | 6.36955654 |
| 2 | MKNK2 | 3.44942762 |
| 3 | EIF2AK3 | 3.40537264 |
| 4 | TSSK6 | 3.32725613 |
| 5 | BCKDK | 3.08473151 |
| 6 | BUB1 | 3.05851693 |
| 7 | MKNK1 | 3.02596273 |
| 8 | PKN2 | 2.71332562 |
| 9 | CDC7 | 2.69749420 |
| 10 | PLK4 | 2.55178113 |
| 11 | WNK3 | 2.42852196 |
| 12 | NEK1 | 2.30792333 |
| 13 | SRPK1 | 2.30065466 |
| 14 | ZAK | 2.19058640 |
| 15 | FLT3 | 2.09790075 |
| 16 | TTK | 2.03231238 |
| 17 | NME1 | 1.97937237 |
| 18 | BRD4 | 1.97716757 |
| 19 | PDK2 | 1.96583460 |
| 20 | PLK3 | 1.92666081 |
| 21 | PBK | 1.92582282 |
| 22 | TNIK | 1.83015204 |
| 23 | PLK2 | 1.74195453 |
| 24 | EIF2AK1 | 1.70762441 |
| 25 | TRIM28 | 1.67596793 |
| 26 | BCR | 1.56247613 |
| 27 | FGFR1 | 1.42368824 |
| 28 | CHEK2 | 1.30665233 |
| 29 | STK16 | 1.22027919 |
| 30 | WEE1 | 1.19058546 |
| 31 | ATR | 1.12992908 |
| 32 | VRK1 | 1.06999249 |
| 33 | PLK1 | 1.04319716 |
| 34 | AKT3 | 1.02585626 |
| 35 | EEF2K | 0.98605163 |
| 36 | NUAK1 | 0.96505770 |
| 37 | BRAF | 0.95905336 |
| 38 | LATS1 | 0.94800031 |
| 39 | ERBB3 | 0.88935144 |
| 40 | CLK1 | 0.88559320 |
| 41 | RPS6KB2 | 0.88101183 |
| 42 | MST4 | 0.86599884 |
| 43 | STK38L | 0.86394731 |
| 44 | NME2 | 0.83593882 |
| 45 | VRK2 | 0.83187874 |
| 46 | BRSK2 | 0.75613199 |
| 47 | ATM | 0.75395005 |
| 48 | EPHA4 | 0.75201695 |
| 49 | SCYL2 | 0.71801791 |
| 50 | CHEK1 | 0.71549527 |
| 51 | CSNK1A1L | 0.68648705 |
| 52 | AURKB | 0.67336735 |
| 53 | PASK | 0.66636571 |
| 54 | CSNK1G3 | 0.66570822 |
| 55 | PNCK | 0.66378044 |
| 56 | WNK4 | 0.63684002 |
| 57 | ARAF | 0.58766218 |
| 58 | CSNK2A2 | 0.58280377 |
| 59 | PAK4 | 0.51753306 |
| 60 | CDK1 | 0.51583467 |
| 61 | CSNK1G2 | 0.50321632 |
| 62 | CDK14 | 0.50017274 |
| 63 | CDK8 | 0.49648701 |
| 64 | CDK2 | 0.49576291 |
| 65 | CSNK1E | 0.49537082 |
| 66 | CDK7 | 0.47763008 |
| 67 | MINK1 | 0.46640782 |
| 68 | CSNK2A1 | 0.45970067 |
| 69 | CCNB1 | 0.44529528 |
| 70 | CSNK1G1 | 0.44379294 |
| 71 | RAF1 | 0.41820293 |
| 72 | FGR | 0.41340347 |
| 73 | BMPR1B | 0.40475750 |
| 74 | CDK18 | 0.40049828 |
| 75 | BRSK1 | 0.39714863 |
| 76 | ALK | 0.39189752 |
| 77 | PAK1 | 0.36318538 |
| 78 | RPS6KA5 | 0.36112136 |
| 79 | MAP3K4 | 0.34632121 |
| 80 | AKT2 | 0.33913365 |
| 81 | CDK11A | 0.33720916 |
| 82 | TLK1 | 0.32187577 |
| 83 | CDK15 | 0.32071317 |
| 84 | TESK2 | 0.31042995 |
| 85 | KDR | 0.30698949 |
| 86 | MAPKAPK3 | 0.30619714 |
| 87 | MAP3K8 | 0.30292098 |
| 88 | CDK12 | 0.29857862 |
| 89 | SIK3 | 0.28353383 |
| 90 | EIF2AK2 | 0.28337776 |
| 91 | FRK | 0.27589682 |
| 92 | MAP2K4 | 0.27216873 |
| 93 | AURKA | 0.26680643 |
| 94 | CSNK1D | 0.26024713 |
| 95 | STK3 | 0.25324703 |
| 96 | CDK4 | 0.24624064 |
| 97 | MAP3K5 | 0.24381969 |
| 98 | OBSCN | 0.24290814 |
| 99 | STK39 | 0.24238897 |
| 100 | INSRR | 0.22597963 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.93903848 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.70157788 |
| 3 | DNA replication_Homo sapiens_hsa03030 | 3.67773539 |
| 4 | Mismatch repair_Homo sapiens_hsa03430 | 3.11314305 |
| 5 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 3.00842120 |
| 6 | Spliceosome_Homo sapiens_hsa03040 | 2.92351659 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.57093243 |
| 8 | RNA transport_Homo sapiens_hsa03013 | 2.52890975 |
| 9 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.45089198 |
| 10 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.39658260 |
| 11 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.34464032 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 2.29403375 |
| 13 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.20422687 |
| 14 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.20386882 |
| 15 | Protein export_Homo sapiens_hsa03060 | 2.18856321 |
| 16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.11643437 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 2.08024213 |
| 18 | Base excision repair_Homo sapiens_hsa03410 | 2.00497537 |
| 19 | Parkinsons disease_Homo sapiens_hsa05012 | 1.97004733 |
| 20 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.95573380 |
| 21 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.89309097 |
| 22 | Cell cycle_Homo sapiens_hsa04110 | 1.79291363 |
| 23 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.70901337 |
| 24 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.64246086 |
| 25 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.64048638 |
| 26 | Basal transcription factors_Homo sapiens_hsa03022 | 1.59156535 |
| 27 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.57717595 |
| 28 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.56745369 |
| 29 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.56638787 |
| 30 | Ribosome_Homo sapiens_hsa03010 | 1.54137937 |
| 31 | Huntingtons disease_Homo sapiens_hsa05016 | 1.47980937 |
| 32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.47326323 |
| 33 | Carbon metabolism_Homo sapiens_hsa01200 | 1.46990255 |
| 34 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.45581126 |
| 35 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.43325464 |
| 36 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.40967793 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 1.35683034 |
| 38 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.27911312 |
| 39 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.25179777 |
| 40 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.21374330 |
| 41 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.18466210 |
| 42 | Legionellosis_Homo sapiens_hsa05134 | 1.15885271 |
| 43 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.09256455 |
| 44 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.03992837 |
| 45 | Alzheimers disease_Homo sapiens_hsa05010 | 0.96457470 |
| 46 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.94697008 |
| 47 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.92968889 |
| 48 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.92574060 |
| 49 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.91531123 |
| 50 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.87793665 |
| 51 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.82993053 |
| 52 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.78113225 |
| 53 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.77390898 |
| 54 | Sulfur relay system_Homo sapiens_hsa04122 | 0.71788660 |
| 55 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.70440869 |
| 56 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.67690162 |
| 57 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.66726642 |
| 58 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.63911398 |
| 59 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.62772156 |
| 60 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.56222985 |
| 61 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.52219299 |
| 62 | Metabolic pathways_Homo sapiens_hsa01100 | 0.51190603 |
| 63 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.50495735 |
| 64 | Nicotine addiction_Homo sapiens_hsa05033 | 0.48911590 |
| 65 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.47745547 |
| 66 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.45658488 |
| 67 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.44563525 |
| 68 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.38422105 |
| 69 | Adherens junction_Homo sapiens_hsa04520 | 0.37821962 |
| 70 | Thyroid cancer_Homo sapiens_hsa05216 | 0.37335721 |
| 71 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.36225252 |
| 72 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.35449303 |
| 73 | Taste transduction_Homo sapiens_hsa04742 | 0.33029391 |
| 74 | Alcoholism_Homo sapiens_hsa05034 | 0.32817304 |
| 75 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.32748516 |
| 76 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.31317688 |
| 77 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.31153543 |
| 78 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.30954734 |
| 79 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.29781683 |
| 80 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.28625724 |
| 81 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.28397606 |
| 82 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.28212937 |
| 83 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.25897928 |
| 84 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.24627131 |
| 85 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.22704671 |
| 86 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.21891136 |
| 87 | Measles_Homo sapiens_hsa05162 | 0.21432263 |
| 88 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.19900492 |
| 89 | Lysine degradation_Homo sapiens_hsa00310 | 0.18017160 |
| 90 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.17664394 |
| 91 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.15988529 |
| 92 | Influenza A_Homo sapiens_hsa05164 | 0.14877857 |
| 93 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.14606067 |
| 94 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.13930754 |
| 95 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.11161832 |
| 96 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.10564428 |
| 97 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.10414062 |
| 98 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.10292607 |
| 99 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.10023118 |
| 100 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.08506583 |

