

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | synaptic vesicle maturation (GO:0016188) | 6.83256628 |
| 2 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 6.62858704 |
| 3 | glutamate secretion (GO:0014047) | 5.90672311 |
| 4 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.85507428 |
| 5 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 5.74547946 |
| 6 | synaptic vesicle exocytosis (GO:0016079) | 5.36331366 |
| 7 | regulation of synaptic vesicle exocytosis (GO:2000300) | 5.23200981 |
| 8 | neuronal action potential propagation (GO:0019227) | 5.12686437 |
| 9 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.00455367 |
| 10 | neurotransmitter secretion (GO:0007269) | 4.79106817 |
| 11 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.68054493 |
| 12 | regulation of synaptic vesicle transport (GO:1902803) | 4.66044814 |
| 13 | cellular potassium ion homeostasis (GO:0030007) | 4.56234230 |
| 14 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 4.55100911 |
| 15 | sodium ion export (GO:0071436) | 4.26775362 |
| 16 | proline transport (GO:0015824) | 4.08856221 |
| 17 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 4.04799865 |
| 18 | locomotory exploration behavior (GO:0035641) | 3.96108825 |
| 19 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.90161517 |
| 20 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.89680054 |
| 21 | membrane depolarization during action potential (GO:0086010) | 3.89498388 |
| 22 | dendritic spine morphogenesis (GO:0060997) | 3.86603587 |
| 23 | neuromuscular synaptic transmission (GO:0007274) | 3.85787871 |
| 24 | regulation of cell communication by electrical coupling (GO:0010649) | 3.85459154 |
| 25 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.84018514 |
| 26 | * regulation of neuronal synaptic plasticity (GO:0048168) | 3.83855717 |
| 27 | neurotransmitter transport (GO:0006836) | 3.83325962 |
| 28 | actin-myosin filament sliding (GO:0033275) | 3.80452134 |
| 29 | muscle filament sliding (GO:0030049) | 3.80452134 |
| 30 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 3.78788235 |
| 31 | vocalization behavior (GO:0071625) | 3.71495153 |
| 32 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.69508122 |
| 33 | skeletal muscle contraction (GO:0003009) | 3.68920844 |
| 34 | regulation of skeletal muscle contraction (GO:0014819) | 3.59958425 |
| 35 | cerebellar granule cell differentiation (GO:0021707) | 3.59879799 |
| 36 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.59399251 |
| 37 | * positive regulation of synapse maturation (GO:0090129) | 3.58666327 |
| 38 | regulation of neurotransmitter levels (GO:0001505) | 3.58303251 |
| 39 | exploration behavior (GO:0035640) | 3.58283737 |
| 40 | potassium ion import (GO:0010107) | 3.57258970 |
| 41 | regulation of synapse structural plasticity (GO:0051823) | 3.57258701 |
| 42 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 3.55264997 |
| 43 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.50516132 |
| 44 | synaptic transmission, glutamatergic (GO:0035249) | 3.47662558 |
| 45 | regulation of relaxation of muscle (GO:1901077) | 3.45682809 |
| 46 | * regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.45072000 |
| 47 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.44228635 |
| 48 | creatine metabolic process (GO:0006600) | 3.43308236 |
| 49 | positive regulation of membrane potential (GO:0045838) | 3.43181596 |
| 50 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 3.41599303 |
| 51 | postsynaptic membrane organization (GO:0001941) | 3.41104134 |
| 52 | regulation of neurotransmitter secretion (GO:0046928) | 3.38564935 |
| 53 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 3.37238241 |
| 54 | potassium ion homeostasis (GO:0055075) | 3.35201995 |
| 55 | positive regulation of neurotransmitter transport (GO:0051590) | 3.30202862 |
| 56 | striated muscle contraction (GO:0006941) | 3.28252824 |
| 57 | regulation of ARF protein signal transduction (GO:0032012) | 3.27801711 |
| 58 | protein localization to synapse (GO:0035418) | 3.23306819 |
| 59 | regulation of neurotransmitter transport (GO:0051588) | 3.20954800 |
| 60 | neuron-neuron synaptic transmission (GO:0007270) | 3.20860733 |
| 61 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.16302920 |
| 62 | L-amino acid import (GO:0043092) | 3.15383996 |
| 63 | glutamate receptor signaling pathway (GO:0007215) | 3.14912709 |
| 64 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.11934841 |
| 65 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.07565914 |
| 66 | membrane depolarization (GO:0051899) | 3.07029077 |
| 67 | neuronal ion channel clustering (GO:0045161) | 3.06914948 |
| 68 | regulation of vesicle fusion (GO:0031338) | 3.05728253 |
| 69 | regulation of calcium ion transmembrane transport (GO:1903169) | 3.05123238 |
| 70 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 3.05123238 |
| 71 | regulation of sodium ion transmembrane transporter activity (GO:2000649) | 3.04706429 |
| 72 | cell communication by electrical coupling (GO:0010644) | 3.04300718 |
| 73 | detection of calcium ion (GO:0005513) | 3.03478930 |
| 74 | regulation of postsynaptic membrane potential (GO:0060078) | 3.02509851 |
| 75 | * regulation of synaptic plasticity (GO:0048167) | 3.02508029 |
| 76 | actin-mediated cell contraction (GO:0070252) | 2.99540284 |
| 77 | gamma-aminobutyric acid transport (GO:0015812) | 2.98952019 |
| 78 | dendritic spine organization (GO:0097061) | 2.96592789 |
| 79 | chemosensory behavior (GO:0007635) | 2.94951357 |
| 80 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.93523234 |
| 81 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 2.93360821 |
| 82 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.91499213 |
| 83 | calcium ion-dependent exocytosis (GO:0017156) | 2.91204213 |
| 84 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.90156018 |
| 85 | auditory behavior (GO:0031223) | 2.89254297 |
| 86 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.87508276 |
| 87 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.84639692 |
| 88 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 2.84587230 |
| 89 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 2.84587230 |
| 90 | * positive regulation of dendritic spine development (GO:0060999) | 2.83045808 |
| 91 | regulation of membrane repolarization (GO:0060306) | 2.83019926 |
| 92 | cellular sodium ion homeostasis (GO:0006883) | 2.82903020 |
| 93 | synaptic vesicle endocytosis (GO:0048488) | 2.82678275 |
| 94 | synaptic transmission (GO:0007268) | 2.82259042 |
| 95 | * regulation of synapse maturation (GO:0090128) | 2.82059630 |
| 96 | regulation of sodium ion transmembrane transport (GO:1902305) | 2.79189923 |
| 97 | signal release (GO:0023061) | 2.78877288 |
| 98 | cellular potassium ion transport (GO:0071804) | 2.77240660 |
| 99 | potassium ion transmembrane transport (GO:0071805) | 2.77240660 |
| 100 | neuromuscular process controlling balance (GO:0050885) | 2.76533462 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.97853182 |
| 2 | DROSHA_22980978_ChIP-Seq_HELA_Human | 3.16445473 |
| 3 | REST_21632747_ChIP-Seq_MESCs_Mouse | 3.06650773 |
| 4 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.99070662 |
| 5 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.93932741 |
| 6 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.68723029 |
| 7 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.68649547 |
| 8 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.60064083 |
| 9 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.45311694 |
| 10 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.43334140 |
| 11 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.40805720 |
| 12 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.39559094 |
| 13 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.35833692 |
| 14 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.30102895 |
| 15 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.26435957 |
| 16 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.20647572 |
| 17 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.18932801 |
| 18 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.08491535 |
| 19 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.08227364 |
| 20 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.04146556 |
| 21 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.02221392 |
| 22 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.02221392 |
| 23 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.98508242 |
| 24 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.97724557 |
| 25 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.84158361 |
| 26 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.72876873 |
| 27 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.71033884 |
| 28 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.69047090 |
| 29 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.66448072 |
| 30 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.66253861 |
| 31 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.61398253 |
| 32 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.54077399 |
| 33 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.53147246 |
| 34 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.52928152 |
| 35 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.43997144 |
| 36 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.42119157 |
| 37 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.41499147 |
| 38 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.30110218 |
| 39 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.29533582 |
| 40 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.29274027 |
| 41 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.24251622 |
| 42 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.20312766 |
| 43 | KDM2B_26808549_Chip-Seq_K562_Human | 1.20039358 |
| 44 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.19745783 |
| 45 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.19396908 |
| 46 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.19370063 |
| 47 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.17911001 |
| 48 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.15505153 |
| 49 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.15255588 |
| 50 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.14554910 |
| 51 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.12741709 |
| 52 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.12017434 |
| 53 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.08683634 |
| 54 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.07951780 |
| 55 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.05889747 |
| 56 | P68_20966046_ChIP-Seq_HELA_Human | 1.03003288 |
| 57 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.00538429 |
| 58 | AR_19668381_ChIP-Seq_PC3_Human | 1.00374885 |
| 59 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.98743009 |
| 60 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.98323098 |
| 61 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97309246 |
| 62 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.93840695 |
| 63 | SA1_27219007_Chip-Seq_Bcells_Human | 0.92859630 |
| 64 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.92698749 |
| 65 | DPY_21335234_ChIP-Seq_ESCs_Mouse | 0.92397788 |
| 66 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.89891264 |
| 67 | SMAD4_21741376_ChIP-Seq_ESCs_Human | 0.88167697 |
| 68 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.87941249 |
| 69 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.87840570 |
| 70 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.87295574 |
| 71 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.86298212 |
| 72 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85949614 |
| 73 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.85436221 |
| 74 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.84055965 |
| 75 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.84048418 |
| 76 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.83794015 |
| 77 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.82804808 |
| 78 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.81699243 |
| 79 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.81243639 |
| 80 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.79244027 |
| 81 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.79098819 |
| 82 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.77635552 |
| 83 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.77054407 |
| 84 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.77033233 |
| 85 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.76250105 |
| 86 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.74900424 |
| 87 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.74653660 |
| 88 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.74268055 |
| 89 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.73961394 |
| 90 | TCF4_23295773_ChIP-Seq_U87_Human | 0.73846084 |
| 91 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.73259138 |
| 92 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.73071894 |
| 93 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.73003916 |
| 94 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.72986378 |
| 95 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.72513499 |
| 96 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.72188369 |
| 97 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.72119219 |
| 98 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.71333545 |
| 99 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.70555967 |
| 100 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.69102634 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004859_abnormal_synaptic_plasticity | 5.18415720 |
| 2 | MP0004270_analgesia | 4.48306069 |
| 3 | MP0003880_abnormal_central_pattern | 4.07870979 |
| 4 | MP0005423_abnormal_somatic_nervous | 3.38447629 |
| 5 | MP0003635_abnormal_synaptic_transmissio | 3.29036906 |
| 6 | MP0004145_abnormal_muscle_electrophysio | 3.22735263 |
| 7 | MP0002064_seizures | 2.99322022 |
| 8 | MP0009745_abnormal_behavioral_response | 2.85775068 |
| 9 | MP0003646_muscle_fatigue | 2.68213562 |
| 10 | MP0003879_abnormal_hair_cell | 2.67416634 |
| 11 | MP0002734_abnormal_mechanical_nocicepti | 2.62754438 |
| 12 | MP0002272_abnormal_nervous_system | 2.61848433 |
| 13 | MP0002063_abnormal_learning/memory/cond | 2.58299818 |
| 14 | MP0009046_muscle_twitch | 2.58057901 |
| 15 | MP0001486_abnormal_startle_reflex | 2.38696602 |
| 16 | MP0000751_myopathy | 2.30942048 |
| 17 | MP0001501_abnormal_sleep_pattern | 2.29188411 |
| 18 | MP0002572_abnormal_emotion/affect_behav | 2.22875447 |
| 19 | MP0003787_abnormal_imprinting | 2.21131589 |
| 20 | MP0001968_abnormal_touch/_nociception | 2.16682520 |
| 21 | MP0002822_catalepsy | 2.13237014 |
| 22 | MP0000749_muscle_degeneration | 2.11364136 |
| 23 | MP0009780_abnormal_chondrocyte_physiolo | 2.09256582 |
| 24 | MP0008569_lethality_at_weaning | 1.94650537 |
| 25 | MP0004130_abnormal_muscle_cell | 1.74803087 |
| 26 | MP0001970_abnormal_pain_threshold | 1.74280707 |
| 27 | MP0002733_abnormal_thermal_nociception | 1.72168294 |
| 28 | MP0004147_increased_porphyrin_level | 1.66355323 |
| 29 | MP0002735_abnormal_chemical_nociception | 1.65992253 |
| 30 | MP0004036_abnormal_muscle_relaxation | 1.65578922 |
| 31 | MP0006276_abnormal_autonomic_nervous | 1.57663784 |
| 32 | MP0003329_amyloid_beta_deposits | 1.52822814 |
| 33 | MP0000747_muscle_weakness | 1.52048415 |
| 34 | MP0002067_abnormal_sensory_capabilities | 1.51883103 |
| 35 | MP0002106_abnormal_muscle_physiology | 1.50609966 |
| 36 | MP0001502_abnormal_circadian_rhythm | 1.46811651 |
| 37 | MP0002638_abnormal_pupillary_reflex | 1.43584331 |
| 38 | MP0001440_abnormal_grooming_behavior | 1.41167579 |
| 39 | MP0002557_abnormal_social/conspecific_i | 1.38361161 |
| 40 | MP0003122_maternal_imprinting | 1.37630491 |
| 41 | MP0005646_abnormal_pituitary_gland | 1.36575134 |
| 42 | MP0005645_abnormal_hypothalamus_physiol | 1.36268146 |
| 43 | MP0003123_paternal_imprinting | 1.36160787 |
| 44 | MP0004924_abnormal_behavior | 1.35517099 |
| 45 | MP0005386_behavior/neurological_phenoty | 1.35517099 |
| 46 | MP0002736_abnormal_nociception_after | 1.33488196 |
| 47 | MP0002066_abnormal_motor_capabilities/c | 1.30645781 |
| 48 | MP0000759_abnormal_skeletal_muscle | 1.28332668 |
| 49 | MP0003633_abnormal_nervous_system | 1.26146808 |
| 50 | MP0004811_abnormal_neuron_physiology | 1.26117463 |
| 51 | MP0002909_abnormal_adrenal_gland | 1.25325657 |
| 52 | MP0002837_dystrophic_cardiac_calcinosis | 1.21255872 |
| 53 | MP0005369_muscle_phenotype | 1.19646018 |
| 54 | MP0001905_abnormal_dopamine_level | 1.17652170 |
| 55 | MP0006036_abnormal_mitochondrial_physio | 1.15882832 |
| 56 | MP0008877_abnormal_DNA_methylation | 1.14432783 |
| 57 | MP0004087_abnormal_muscle_fiber | 1.12878093 |
| 58 | MP0004885_abnormal_endolymph | 1.12572053 |
| 59 | MP0000013_abnormal_adipose_tissue | 1.12550817 |
| 60 | MP0005620_abnormal_muscle_contractility | 1.11970329 |
| 61 | MP0005535_abnormal_body_temperature | 1.10262520 |
| 62 | MP0002229_neurodegeneration | 1.08903231 |
| 63 | MP0002332_abnormal_exercise_endurance | 1.06252371 |
| 64 | MP0002882_abnormal_neuron_morphology | 1.05515672 |
| 65 | MP0002876_abnormal_thyroid_physiology | 1.04669219 |
| 66 | MP0001984_abnormal_olfaction | 1.02694777 |
| 67 | MP0003631_nervous_system_phenotype | 1.00279109 |
| 68 | MP0001986_abnormal_taste_sensitivity | 1.00022528 |
| 69 | MP0003690_abnormal_glial_cell | 0.97683420 |
| 70 | MP0002269_muscular_atrophy | 0.97543574 |
| 71 | MP0005551_abnormal_eye_electrophysiolog | 0.96175259 |
| 72 | MP0008872_abnormal_physiological_respon | 0.95489887 |
| 73 | MP0002184_abnormal_innervation | 0.94534834 |
| 74 | MP0000955_abnormal_spinal_cord | 0.92529263 |
| 75 | MP0004484_altered_response_of | 0.92445223 |
| 76 | MP0001485_abnormal_pinna_reflex | 0.92141265 |
| 77 | MP0004215_abnormal_myocardial_fiber | 0.91407183 |
| 78 | MP0000750_abnormal_muscle_regeneration | 0.85851695 |
| 79 | MP0004510_myositis | 0.85472219 |
| 80 | MP0000920_abnormal_myelination | 0.85169370 |
| 81 | MP0001963_abnormal_hearing_physiology | 0.85089177 |
| 82 | MP0004043_abnormal_pH_regulation | 0.84553686 |
| 83 | MP0001765_abnormal_ion_homeostasis | 0.83059555 |
| 84 | MP0002078_abnormal_glucose_homeostasis | 0.82987780 |
| 85 | MP0004142_abnormal_muscle_tone | 0.82407023 |
| 86 | MP0003137_abnormal_impulse_conducting | 0.81384502 |
| 87 | MP0005451_abnormal_body_composition | 0.80957851 |
| 88 | MP0004085_abnormal_heartbeat | 0.80672127 |
| 89 | MP0008874_decreased_physiological_sensi | 0.79181629 |
| 90 | MP0003283_abnormal_digestive_organ | 0.79124129 |
| 91 | MP0003045_fibrosis | 0.76707256 |
| 92 | MP0002693_abnormal_pancreas_physiology | 0.75365633 |
| 93 | MP0000778_abnormal_nervous_system | 0.73418611 |
| 94 | MP0002069_abnormal_eating/drinking_beha | 0.71500082 |
| 95 | MP0003075_altered_response_to | 0.71185440 |
| 96 | MP0003172_abnormal_lysosome_physiology | 0.69282433 |
| 97 | MP0004742_abnormal_vestibular_system | 0.69171710 |
| 98 | MP0003183_abnormal_peptide_metabolism | 0.68123313 |
| 99 | MP0005330_cardiomyopathy | 0.67609131 |
| 100 | MP0002971_abnormal_brown_adipose | 0.67216261 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Muscle fiber inclusion bodies (HP:0100299) | 6.45766442 |
| 2 | Nemaline bodies (HP:0003798) | 6.42991581 |
| 3 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 6.18832020 |
| 4 | Exercise-induced myalgia (HP:0003738) | 5.40033944 |
| 5 | Myokymia (HP:0002411) | 5.02431331 |
| 6 | Focal motor seizures (HP:0011153) | 4.92904243 |
| 7 | Type 1 muscle fiber predominance (HP:0003803) | 4.35846200 |
| 8 | Exercise-induced muscle cramps (HP:0003710) | 4.27239138 |
| 9 | Focal seizures (HP:0007359) | 4.03442802 |
| 10 | Febrile seizures (HP:0002373) | 4.00060023 |
| 11 | Muscle hypertrophy of the lower extremities (HP:0008968) | 3.95920361 |
| 12 | Distal arthrogryposis (HP:0005684) | 3.91991086 |
| 13 | Ankle clonus (HP:0011448) | 3.88311638 |
| 14 | Myopathic facies (HP:0002058) | 3.78645132 |
| 15 | Fetal akinesia sequence (HP:0001989) | 3.63896315 |
| 16 | Calf muscle hypertrophy (HP:0008981) | 3.54536842 |
| 17 | Epileptic encephalopathy (HP:0200134) | 3.49102274 |
| 18 | EMG: myopathic abnormalities (HP:0003458) | 3.43535675 |
| 19 | Round ear (HP:0100830) | 3.34802677 |
| 20 | Visual hallucinations (HP:0002367) | 3.32755258 |
| 21 | Abnormality of binocular vision (HP:0011514) | 3.29994303 |
| 22 | Diplopia (HP:0000651) | 3.29994303 |
| 23 | Atonic seizures (HP:0010819) | 3.26383638 |
| 24 | Action tremor (HP:0002345) | 3.21970857 |
| 25 | Generalized tonic-clonic seizures (HP:0002069) | 3.16879572 |
| 26 | Muscle fiber splitting (HP:0003555) | 3.00277718 |
| 27 | Hyporeflexia of lower limbs (HP:0002600) | 2.98506260 |
| 28 | Rhabdomyolysis (HP:0003201) | 2.96896043 |
| 29 | Myoglobinuria (HP:0002913) | 2.96857603 |
| 30 | Difficulty running (HP:0009046) | 2.96419252 |
| 31 | Bundle branch block (HP:0011710) | 2.93350598 |
| 32 | Limb dystonia (HP:0002451) | 2.87830530 |
| 33 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.84492619 |
| 34 | Absence seizures (HP:0002121) | 2.83610609 |
| 35 | Progressive cerebellar ataxia (HP:0002073) | 2.82970680 |
| 36 | Supranuclear gaze palsy (HP:0000605) | 2.80062162 |
| 37 | Akinesia (HP:0002304) | 2.79924377 |
| 38 | Muscle stiffness (HP:0003552) | 2.77680995 |
| 39 | Rimmed vacuoles (HP:0003805) | 2.71972442 |
| 40 | Myotonia (HP:0002486) | 2.71265399 |
| 41 | Frequent falls (HP:0002359) | 2.69965216 |
| 42 | Dialeptic seizures (HP:0011146) | 2.63812164 |
| 43 | Postural instability (HP:0002172) | 2.61153021 |
| 44 | Spastic gait (HP:0002064) | 2.60894726 |
| 45 | Epileptiform EEG discharges (HP:0011182) | 2.60695338 |
| 46 | Poor eye contact (HP:0000817) | 2.60663671 |
| 47 | Subaortic stenosis (HP:0001682) | 2.60558774 |
| 48 | Abnormality of the left ventricular outflow tract (HP:0011103) | 2.60558774 |
| 49 | Sudden death (HP:0001699) | 2.57215019 |
| 50 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.54817676 |
| 51 | Abnormality of the calf musculature (HP:0001430) | 2.53709980 |
| 52 | Abnormal eating behavior (HP:0100738) | 2.48702667 |
| 53 | Ulnar deviation of the wrist (HP:0003049) | 2.48073263 |
| 54 | Ventricular fibrillation (HP:0001663) | 2.45178133 |
| 55 | EEG with generalized epileptiform discharges (HP:0011198) | 2.42720332 |
| 56 | EMG: neuropathic changes (HP:0003445) | 2.41190676 |
| 57 | Obstructive sleep apnea (HP:0002870) | 2.34795324 |
| 58 | Papilledema (HP:0001085) | 2.34583347 |
| 59 | Hypsarrhythmia (HP:0002521) | 2.31131126 |
| 60 | Tetraplegia (HP:0002445) | 2.29906736 |
| 61 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.29439404 |
| 62 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.26921998 |
| 63 | Neck muscle weakness (HP:0000467) | 2.26040231 |
| 64 | Hemiparesis (HP:0001269) | 2.25507413 |
| 65 | Anxiety (HP:0000739) | 2.25294186 |
| 66 | Torticollis (HP:0000473) | 2.25023681 |
| 67 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.23944299 |
| 68 | Heart block (HP:0012722) | 2.23282876 |
| 69 | Depression (HP:0000716) | 2.22243116 |
| 70 | Cerebral hypomyelination (HP:0006808) | 2.18599543 |
| 71 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.16979689 |
| 72 | Broad-based gait (HP:0002136) | 2.16301739 |
| 73 | Clonus (HP:0002169) | 2.12521964 |
| 74 | Asymmetric septal hypertrophy (HP:0001670) | 2.10579758 |
| 75 | Hyperkalemia (HP:0002153) | 2.10343868 |
| 76 | Lower limb muscle weakness (HP:0007340) | 2.09620482 |
| 77 | Focal dystonia (HP:0004373) | 2.08651716 |
| 78 | Abnormal EKG (HP:0003115) | 2.07806122 |
| 79 | Urinary urgency (HP:0000012) | 2.07326936 |
| 80 | Prolonged QT interval (HP:0001657) | 2.06919743 |
| 81 | Rigidity (HP:0002063) | 2.06595338 |
| 82 | Bradykinesia (HP:0002067) | 2.06149233 |
| 83 | Status epilepticus (HP:0002133) | 2.03401375 |
| 84 | Abnormal social behavior (HP:0012433) | 2.02251097 |
| 85 | Impaired social interactions (HP:0000735) | 2.02251097 |
| 86 | Truncal ataxia (HP:0002078) | 2.00950441 |
| 87 | Distal lower limb muscle weakness (HP:0009053) | 2.00393688 |
| 88 | Mutism (HP:0002300) | 1.99342092 |
| 89 | Intention tremor (HP:0002080) | 1.99130178 |
| 90 | Annular pancreas (HP:0001734) | 1.96472511 |
| 91 | Sleep apnea (HP:0010535) | 1.95975970 |
| 92 | Hemiplegia (HP:0002301) | 1.95870500 |
| 93 | Dysmetria (HP:0001310) | 1.95866320 |
| 94 | Abnormal atrioventricular conduction (HP:0005150) | 1.95720182 |
| 95 | Calcaneovalgus deformity (HP:0001848) | 1.94913363 |
| 96 | Malignant hyperthermia (HP:0002047) | 1.93935277 |
| 97 | Lower limb amyotrophy (HP:0007210) | 1.93817423 |
| 98 | Delusions (HP:0000746) | 1.90502812 |
| 99 | Nonprogressive disorder (HP:0003680) | 1.88623047 |
| 100 | Rapidly progressive (HP:0003678) | 1.87737869 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PHKG2 | 4.49989582 |
| 2 | PHKG1 | 4.49989582 |
| 3 | OBSCN | 4.42168818 |
| 4 | DAPK2 | 3.89387851 |
| 5 | EPHA4 | 3.83730993 |
| 6 | MARK1 | 3.54253189 |
| 7 | NTRK3 | 3.24003329 |
| 8 | PAK6 | 2.66336118 |
| 9 | PINK1 | 2.26076568 |
| 10 | UHMK1 | 2.02290156 |
| 11 | MAP3K9 | 1.92806012 |
| 12 | PRKD3 | 1.84541206 |
| 13 | NTRK2 | 1.71601659 |
| 14 | CAMKK1 | 1.65599987 |
| 15 | MAPK12 | 1.59057307 |
| 16 | TTN | 1.58325572 |
| 17 | MAPK13 | 1.56831040 |
| 18 | CAMK1 | 1.44072939 |
| 19 | CASK | 1.43595677 |
| 20 | MINK1 | 1.39779866 |
| 21 | RIPK4 | 1.29963146 |
| 22 | DAPK1 | 1.22494989 |
| 23 | MAP2K6 | 1.22209431 |
| 24 | CDK19 | 1.22044937 |
| 25 | CDK5 | 1.21684893 |
| 26 | MAP2K4 | 1.17366470 |
| 27 | SGK223 | 1.15360635 |
| 28 | SGK494 | 1.15360635 |
| 29 | ARAF | 1.12800401 |
| 30 | STK11 | 1.07828826 |
| 31 | SIK2 | 1.06935743 |
| 32 | PRKCH | 1.05893305 |
| 33 | PLK2 | 1.04621372 |
| 34 | GRK5 | 1.01245858 |
| 35 | PAK3 | 1.00288274 |
| 36 | CAMK2B | 1.00008252 |
| 37 | MAP3K7 | 0.99879692 |
| 38 | RIPK1 | 0.99171422 |
| 39 | MARK2 | 0.98711635 |
| 40 | OXSR1 | 0.97333341 |
| 41 | CAMK2G | 0.96037417 |
| 42 | CAMK2A | 0.94044593 |
| 43 | SGK2 | 0.92924544 |
| 44 | CAMK4 | 0.90145402 |
| 45 | PRKCG | 0.89229340 |
| 46 | TNK2 | 0.88297076 |
| 47 | LIMK1 | 0.87796288 |
| 48 | PIK3CG | 0.87239034 |
| 49 | KSR2 | 0.85535421 |
| 50 | FRK | 0.84609506 |
| 51 | LATS2 | 0.83432758 |
| 52 | MAP3K11 | 0.83260367 |
| 53 | PDK1 | 0.82443793 |
| 54 | INSRR | 0.81958076 |
| 55 | SGK3 | 0.81877565 |
| 56 | STK38 | 0.81250182 |
| 57 | MAP3K4 | 0.80917621 |
| 58 | SGK1 | 0.80895597 |
| 59 | PDPK1 | 0.80521762 |
| 60 | CCNB1 | 0.77928143 |
| 61 | MAP3K1 | 0.75834131 |
| 62 | PKN1 | 0.75246049 |
| 63 | PRPF4B | 0.73227492 |
| 64 | CAMKK2 | 0.70413838 |
| 65 | MAP3K13 | 0.69176777 |
| 66 | MUSK | 0.68636076 |
| 67 | CAMK2D | 0.67877009 |
| 68 | NEK6 | 0.64505922 |
| 69 | DYRK1A | 0.63702658 |
| 70 | NME1 | 0.61753995 |
| 71 | PRKAA1 | 0.61699249 |
| 72 | TESK1 | 0.57635651 |
| 73 | RPS6KA3 | 0.56064605 |
| 74 | MAPK10 | 0.55575467 |
| 75 | CDK15 | 0.54320522 |
| 76 | PRKG1 | 0.50910974 |
| 77 | CDK18 | 0.50749784 |
| 78 | CDK11A | 0.50341829 |
| 79 | PRKG2 | 0.50014605 |
| 80 | ALK | 0.49157494 |
| 81 | MAP2K7 | 0.48157653 |
| 82 | CDK14 | 0.47533582 |
| 83 | PRKACA | 0.44403409 |
| 84 | MAP2K1 | 0.41913194 |
| 85 | PRKCZ | 0.39224837 |
| 86 | DAPK3 | 0.38623094 |
| 87 | PRKCA | 0.38586362 |
| 88 | NTRK1 | 0.38067162 |
| 89 | BRAF | 0.38018782 |
| 90 | BMPR2 | 0.35418783 |
| 91 | MAP3K2 | 0.35370800 |
| 92 | WNK4 | 0.35290994 |
| 93 | PRKAA2 | 0.34751926 |
| 94 | ROCK1 | 0.33294327 |
| 95 | TYRO3 | 0.33029756 |
| 96 | MAPK4 | 0.32563515 |
| 97 | RPS6KB1 | 0.31475430 |
| 98 | AKT2 | 0.29435641 |
| 99 | FGFR2 | 0.28660427 |
| 100 | MAPK8 | 0.27836070 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.45851461 |
| 2 | Nicotine addiction_Homo sapiens_hsa05033 | 3.33741745 |
| 3 | Insulin secretion_Homo sapiens_hsa04911 | 2.84807992 |
| 4 | Circadian entrainment_Homo sapiens_hsa04713 | 2.58296784 |
| 5 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.54366475 |
| 6 | Long-term potentiation_Homo sapiens_hsa04720 | 2.52749146 |
| 7 | GABAergic synapse_Homo sapiens_hsa04727 | 2.35245657 |
| 8 | Morphine addiction_Homo sapiens_hsa05032 | 2.20951529 |
| 9 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.19424979 |
| 10 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.16172915 |
| 11 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.15362213 |
| 12 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.13406541 |
| 13 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 2.11313022 |
| 14 | Gastric acid secretion_Homo sapiens_hsa04971 | 2.04349091 |
| 15 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 2.01424463 |
| 16 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 2.00919386 |
| 17 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.95943488 |
| 18 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.91702741 |
| 19 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.85718585 |
| 20 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.69783285 |
| 21 | Salivary secretion_Homo sapiens_hsa04970 | 1.69138071 |
| 22 | Renin secretion_Homo sapiens_hsa04924 | 1.63816135 |
| 23 | Cocaine addiction_Homo sapiens_hsa05030 | 1.62514051 |
| 24 | Circadian rhythm_Homo sapiens_hsa04710 | 1.53966361 |
| 25 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.40459025 |
| 26 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.30183828 |
| 27 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.29673387 |
| 28 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.28861163 |
| 29 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.28437569 |
| 30 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.27353645 |
| 31 | Long-term depression_Homo sapiens_hsa04730 | 1.27081363 |
| 32 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.26878128 |
| 33 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.26750057 |
| 34 | Phototransduction_Homo sapiens_hsa04744 | 1.19574274 |
| 35 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.17668443 |
| 36 | Olfactory transduction_Homo sapiens_hsa04740 | 1.17453805 |
| 37 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.17253312 |
| 38 | Taste transduction_Homo sapiens_hsa04742 | 1.14775031 |
| 39 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.12428522 |
| 40 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.12406625 |
| 41 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.11532998 |
| 42 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.10945878 |
| 43 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.10735483 |
| 44 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.09986941 |
| 45 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.08311445 |
| 46 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.05498852 |
| 47 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.04858464 |
| 48 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.99050055 |
| 49 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.97988830 |
| 50 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.97917628 |
| 51 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.97005600 |
| 52 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.92239921 |
| 53 | Alzheimers disease_Homo sapiens_hsa05010 | 0.81048337 |
| 54 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.80883880 |
| 55 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.79728134 |
| 56 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.79321941 |
| 57 | Bile secretion_Homo sapiens_hsa04976 | 0.78875376 |
| 58 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.78201292 |
| 59 | Melanogenesis_Homo sapiens_hsa04916 | 0.74550812 |
| 60 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.73946940 |
| 61 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.73554563 |
| 62 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.72374281 |
| 63 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.67919755 |
| 64 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.63798711 |
| 65 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.63214662 |
| 66 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.61898183 |
| 67 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.61450335 |
| 68 | Glioma_Homo sapiens_hsa05214 | 0.60741562 |
| 69 | Gap junction_Homo sapiens_hsa04540 | 0.60612124 |
| 70 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.59372214 |
| 71 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.57665643 |
| 72 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.56726216 |
| 73 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.55077741 |
| 74 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.53850877 |
| 75 | Mineral absorption_Homo sapiens_hsa04978 | 0.53555321 |
| 76 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.53403292 |
| 77 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.49194318 |
| 78 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.49110974 |
| 79 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.49015262 |
| 80 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.44887399 |
| 81 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.44785214 |
| 82 | Parkinsons disease_Homo sapiens_hsa05012 | 0.44485927 |
| 83 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.42971978 |
| 84 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.42810723 |
| 85 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.41986288 |
| 86 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.40379760 |
| 87 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.40104763 |
| 88 | Histidine metabolism_Homo sapiens_hsa00340 | 0.39432132 |
| 89 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.38981314 |
| 90 | Axon guidance_Homo sapiens_hsa04360 | 0.36465614 |
| 91 | Insulin resistance_Homo sapiens_hsa04931 | 0.35969420 |
| 92 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.35242325 |
| 93 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.34730039 |
| 94 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.34233791 |
| 95 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.32312773 |
| 96 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.32061900 |
| 97 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.29721799 |
| 98 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.29432583 |
| 99 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.29046295 |
| 100 | Tight junction_Homo sapiens_hsa04530 | 0.28309221 |

